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format: html
page-title: Genomes to Life: Putting Microbes to Work
crumb: Microbes
/restindex
<div align="right">
<table width="100%">
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<td><img src="sidebar2.jpg" height="1200" width="90" /></td>
<td align="left" valign="top">
<div align="right"><b><font face="Book Antiqua"><font
color="#800040"><font size="+3">Genomes to Life: Putting Microbes
to Work</font></font></font></b><br />
<hr align="right" width="80%" />
<b><font face="Arial,Helvetica"><font color="#000000"><font
size="-1">Genomics and Its Impact on Science and Society: The Human
Genome Project and Beyond</font></font></font></b></div>
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<td><a href="glossary.html"><img src="next.jpg" height="9"
width="15" border="0" /></a></td>
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<div align="center"><a href="1.html"><font size="-1"
face="Arial,Helvetica">Primer</font></a> <font size="-1">- <a
href="2.html"><font face="Arial,Helvetica">History</font></a> - <a
href="4.html"><font face="Arial,Helvetica">Insights</font></a> -
<a href="6.html"><font face="Arial,Helvetica">Medicine</font></a>
- <a href="7.html"><font
face="Arial,Helvetica">Benefits</font></a> - <a
href="8.html"><font face="Arial,Helvetica">Concerns</font></a> -
<a href="5.html"><font
face="Arial, Helvetica, sans-serif">Beyond</font></a> - <a
href="3.html"><font
face="Arial, Helvetica, sans-serif">Systems</font></a> - <a
href="9.html"><font
face="Arial, Helvetica, sans-serif">Microbes</font></a> - <a
href="glossary.html"><font
face="Arial,Helvetica">Dictionary</font></a> - <a
href="index.html"><font
face="Arial, Helvetica, sans-serif">Home</font></a></font></div>
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<table width="100%" border="0" cellspacing="3" cellpadding="3">
<tr>
<td><img src="methanococcus.jpg" width="150" height="150"
align="left" /><font color="#800040"
face="Arial, Helvetica, sans-serif"><em><strong>Methanococcus
jannaschii</strong></em></font><font
face="Arial, Helvetica, sans-serif"><br />
Produces methane, an important energy source; contains enzymes that
withstand high temperatures and pressures; possibly useful for
industrial processes.</font></td>
</tr>
<tr>
<td><font face="Arial, Helvetica, sans-serif"><em><font
face="Arial, Helvetica, sans-serif"><img src="deinococcus.jpg"
width="126" height="150" align="right" /></font><font
color="#800040"><strong>Deinococcus
radiodurans</strong></font></em><br />
Survives extremely high levels of radiation and has high potential
for radioactive waste cleanup.</font></td>
</tr>
<tr>
<td><img src="thalassiosira.jpg" width="150" height="124"
align="left" /><font face="Arial, Helvetica, sans-serif"><em><font
color="#800040"><strong>Thalassiosira
pseudonana</strong></font></em><br />
Ocean diatom that is major participant in biological pumping of
carbon to ocean depths and has potential for mitigating global
climate change.</font></td>
</tr>
<tr>
<td><font face="Arial, Helvetica, sans-serif">The DOE <font
color="#800040"><strong><em>Microbial Genome
Program</em></strong></font><br />
(MGP) studies the DNA of microbes that may be useful in helping
DOE fulfill its missions in energy production, environmental waste
cleanup, and mitigation of the effects of global climate change.
(For more information, see MGP Web site (<a
href="http://www.ornl.gov/microbialgenomes/">www.ornl.gov/microbialgenomes/</a>).</font></td>
</tr>
</table>
<p> </p>
<p><b><font face="Arial,Helvetica"><font color="#800040"><font
size="+1">A Potential Application of Knowledge Gained in GTL
Research</font><font size="+2"><br />
<img src="OPHmembrane.jpg" width="250" height="200"
align="left" /></font></font></font></b> <font
face="Arial,Helvetica"><font color="#800040">Learning about the
inner workings of microbes can lead to discovery of ways to isolate
and use their components to develop new, synthetic nanostructures
that carry out some of the functions of living cells. <b><br />
</b></font></font></p>
<p><font face="Arial, Helvetica, sans-serif">In this figure, an
enzyme (green) has been embedded in a synthetic membrane that
enhances its activity and stability. The enzyme transforms toxic
substances (purple molecules at left) to harmless by-products
(yellow and red molecules at right). [C. Lei, Y. Shin, J. Liu, and
E. J. Ackerman (Pacific Northwest National Laboratory), J. Am.
Chem. Soc. 124, 11242–43 (2002)]</font></p>
<p><font face="Arial,Helvetica"><font
face="Arial, Helvetica, sans-serif">The knowledge gained from
Genomes to Life research could enable others to develop efficient
enzyme-based ways to produce energy, remove or inactivate
contaminants, and store carbon to mitigate global climate change.
Other potential highly useful applications are food processing,
pharmaceuticals, separations, and the production of industrial
chemicals.</font></font></p>
<center>
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<td>
<div align="right"><a href="5.html"><img src="previous.jpg"
height="9" width="15" border="0" /></a></div>
</td>
<td>
<div align="right"><a href="index.html"><img src="atcg.jpg"
height="30" width="30" border="0" /></a></div>
</td>
<td><a href="glossary.html"><img src="next.jpg" height="9"
width="15" border="0" /></a></td>
</tr>
</table>
<div align="center"><a href="1.html"><font size="-1"
face="Arial,Helvetica">Primer</font></a> <font size="-1">- <a
href="2.html"><font face="Arial,Helvetica">History</font></a> - <a
href="4.html"><font face="Arial,Helvetica">Insights</font></a> -
<a href="6.html"><font face="Arial,Helvetica">Medicine</font></a>
- <a href="7.html"><font
face="Arial,Helvetica">Benefits</font></a> - <a
href="8.html"><font face="Arial,Helvetica">Concerns</font></a> -
<a href="5.html"><font
face="Arial, Helvetica, sans-serif">Beyond</font></a> - <a
href="3.html"><font
face="Arial, Helvetica, sans-serif">Systems</font></a> - <a
href="9.html"><font
face="Arial, Helvetica, sans-serif">Microbes</font></a> - <a
href="glossary.html"><font
face="Arial,Helvetica">Dictionary</font></a> - <a
href="index.html"><font
face="Arial, Helvetica, sans-serif">Home</font></a></font></div>
</center>
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</table>
</div>
<table border="1" width="100%">
<tr>
<td><a href="http://www.ornl.gov/TechResources/Human_Genome/"><img
src="HGPlogo1.jpg" border="0" height="107" width="108" /></a></td>
<td>The online presentation of this publication is a special
feature of the <a
href="http://www.ornl.gov/TechResources/Human_Genome/">Human Genome
Project Information Web site</a>.</td>
</tr>
</table>
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