/usr/share/doc/setserial/serial.conf is in setserial 2.17-50.
This file is owned by root:root, with mode 0o644.
The actual contents of the file can be viewed below.
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###AUTOSAVE###
#
# If you want AUTOSAVE switched on, make the AUTOSAVE line above the
# FIRST line of the file.
#
# AUTOSAVE-ONCE, if it is first, will save the port status and then move
# itself to the second line of the file (thus effectively stopping further
# AUTOSAVEs).
#
# This is a sample serial.conf file. You should uncomment out and modify
# the relevant lines as necessary.
#
# These are the standard COM1 through COM4 devices
#
#/dev/ttyS0 uart 16450 port 0x3F8 irq 4
#/dev/ttyS1 uart 16450 port 0x2F8 irq 3
#/dev/ttyS2 uart 16450 port 0x3E8 irq 4
#/dev/ttyS3 uart 16450 port 0x2E8 irq 3
# These are the first set of AST Fourport ports
#
#/dev/ttyS4 uart 16450 port 0x1A0 irq 9 fourport
#/dev/ttyS5 uart 16450 port 0x1A8 irq 9 fourport
#/dev/ttyS6 uart 16450 port 0x1B0 irq 9 fourport
#/dev/ttyS7 uart 16450 port 0x1B8 irq 9 fourport
# This enables the new multiport masking feature, which is highly recommened
# for AST FourPort boards.
#
#/dev/ttyS4 set_multiport port1 0x1BF mask1 0xf match1 0xf
# These are the second set of AST Fourport ports
#
#/dev/ttyS8 uart 16450 port 0x2A0 irq 5 fourport
#/dev/ttyS9 uart 16450 port 0x2A8 irq 5 fourport
#/dev/ttyS10 uart 16450 port 0x2B0 irq 5 fourport
#/dev/ttyS11 uart 16450 port 0x2B8 irq 5 fourport
# This enables the new multiport masking feature, which is highly recommened
# for AST FourPort boards.
#
#/dev/ttyS8 set_multiport port1 0x2BF mask1 0xf match1 0xf
# These are the 3rd and 4th ports on the Accent Async board.
#
#/dev/ttyS12 uart 16450 port 0x330 irq 4
#/dev/ttyS13 uart 16450 port 0x338 irq 4
# These are two spare devices you can use to customize for
# some board which is not supported above....
#
#/dev/ttyS14 uart XXXXX port XXXX irq X
#/dev/ttyS15 uart XXXXX port XXXX irq X
# These are the ports used for either the Usenet Serial II
# board, or the Boca Board 4, 8, or 16 port boards.
#
# Uncomment only the first 4 lines for the Usenet Serial II board,
# and uncomment the first 4, 8, or all 16 lines for the
# Boca Board BB-1004, BB-1008, and BB-2016 respectively.
#
#/dev/ttyS16 uart 16550A port 0x100 irq 12
#/dev/ttyS17 uart 16550A port 0x108 irq 12
#/dev/ttyS18 uart 16550A port 0x110 irq 12
#/dev/ttyS19 uart 16550A port 0x118 irq 12
#/dev/ttyS20 uart 16550A port 0x120 irq 12
#/dev/ttyS21 uart 16550A port 0x128 irq 12
#/dev/ttyS22 uart 16550A port 0x130 irq 12
#/dev/ttyS23 uart 16550A port 0x138 irq 12
#/dev/ttyS24 uart 16550A port 0x140 irq 12
#/dev/ttyS25 uart 16550A port 0x148 irq 12
#/dev/ttyS26 uart 16550A port 0x150 irq 12
#/dev/ttyS27 uart 16550A port 0x158 irq 12
#/dev/ttyS28 uart 16550A port 0x160 irq 12
#/dev/ttyS29 uart 16550A port 0x168 irq 12
#/dev/ttyS30 uart 16550A port 0x170 irq 12
#/dev/ttyS31 uart 16550A port 0x178 irq 12
# This enables the new multiport masking feature, which is highly recommened
# for Bocaboard ports. Uncomment only the first line if you have a
# BB-1004 or BB-1008. Uncomment both lines if you have a BB-2016.
# These numbers assume the Bocaboard is located at address 0x100. If you
# change this, remember to change the port1 and port2 addresses.
#
#/dev/ttyS16 set_multiport port1 0x107 mask1 0xff match1 0
#/dev/ttyS16 set_multiport port2 0x147 mask2 0xff match2 0
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