This file is indexed.

/usr/share/perl5/Bio/SearchIO/hmmer3.pm is in libbio-perl-perl 1.6.901-3.

This file is owned by root:root, with mode 0o644.

The actual contents of the file can be viewed below.

  1
  2
  3
  4
  5
  6
  7
  8
  9
 10
 11
 12
 13
 14
 15
 16
 17
 18
 19
 20
 21
 22
 23
 24
 25
 26
 27
 28
 29
 30
 31
 32
 33
 34
 35
 36
 37
 38
 39
 40
 41
 42
 43
 44
 45
 46
 47
 48
 49
 50
 51
 52
 53
 54
 55
 56
 57
 58
 59
 60
 61
 62
 63
 64
 65
 66
 67
 68
 69
 70
 71
 72
 73
 74
 75
 76
 77
 78
 79
 80
 81
 82
 83
 84
 85
 86
 87
 88
 89
 90
 91
 92
 93
 94
 95
 96
 97
 98
 99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
# $Id: bioperl.lisp 15559 2009-02-23 12:11:20Z maj $
#
# BioPerl module for Bio::SearchIO::hmmer3
#
# Please direct questions and support issues to <bioperl-l@bioperl.org>
#
# Cared for by Thomas Sharpton <thomas.sharpton@gmail.com>
#
# Copyright Thomas Sharpton
#
# You may distribute this module under the same terms as perl itself

# POD documentation - main docs before the code

=head1 NAME

Bio::SearchIO::hmmer3 - DESCRIPTION of Object

=head1 SYNOPSIS

Give standard usage here

=head1 DESCRIPTION

Describe the object here

=head1 FEEDBACK

=head2 Mailing Lists

User feedback is an integral part of the evolution of this and other
Bioperl modules. Send your comments and suggestions preferably to
the Bioperl mailing list.  Your participation is much appreciated.

  bioperl-l@bioperl.org                  - General discussion
  http://bioperl.org/wiki/Mailing_lists  - About the mailing lists

=head2 Support

Please direct usage questions or support issues to the mailing list:

L<bioperl-l@bioperl.org>

rather than to the module maintainer directly. Many experienced and
reponsive experts will be able look at the problem and quickly
address it. Please include a thorough description of the problem
with code and data examples if at all possible.

=head2 Reporting Bugs

Report bugs to the Bioperl bug tracking system to help us keep track
of the bugs and their resolution. Bug reports can be submitted via
the web:

  https://redmine.open-bio.org/projects/bioperl/

=head1 AUTHOR - Thomas Sharpton

Email thomas.sharpton@gmail.com

Describe contact details here

=head1 CONTRIBUTORS

Additional contributors names and emails here

=head1 APPENDIX

The rest of the documentation details each of the object methods.
Internal methods are usually preceded with a _

=cut


# Let the code begin...

package Bio::SearchIO::hmmer3;

use strict;
use Data::Dumper;
use Bio::Factory::ObjectFactory;
use vars qw(%MAPPING %MODEMAP);
use base qw(Bio::SearchIO::hmmer);

BEGIN {

    # mapping of HMMER items to Bioperl hash keys
    %MODEMAP = (
        'HMMER_Output' => 'result',
        'Hit'          => 'hit',
        'Hsp'          => 'hsp'
    );

    %MAPPING = (
        'Hsp_bit-score'   => 'HSP-bits',
        'Hsp_score'       => 'HSP-score',
        'Hsp_evalue'      => 'HSP-evalue',
        'Hsp_query-from'  => 'HSP-query_start',
        'Hsp_query-to'    => 'HSP-query_end',
        'Hsp_hit-from'    => 'HSP-hit_start',
        'Hsp_hit-to'      => 'HSP-hit_end',
        'Hsp_positive'    => 'HSP-conserved',
        'Hsp_identity'    => 'HSP-identical',
        'Hsp_gaps'        => 'HSP-hsp_gaps',
        'Hsp_hitgaps'     => 'HSP-hit_gaps',
        'Hsp_querygaps'   => 'HSP-query_gaps',
        'Hsp_qseq'        => 'HSP-query_seq',
        'Hsp_hseq'        => 'HSP-hit_seq',
        'Hsp_midline'     => 'HSP-homology_seq',
        'Hsp_align-len'   => 'HSP-hsp_length',
        'Hsp_query-frame' => 'HSP-query_frame',
        'Hsp_hit-frame'   => 'HSP-hit_frame',

        'Hit_id'        => 'HIT-name',
        'Hit_len'       => 'HIT-length',
        'Hit_accession' => 'HIT-accession',
        'Hit_desc'      => 'HIT-description',
        'Hit_signif'    => 'HIT-significance',
        'Hit_score'     => 'HIT-score',

        'HMMER_program'   => 'RESULT-algorithm_name',
        'HMMER_version'   => 'RESULT-algorithm_version',
        'HMMER_query-def' => 'RESULT-query_name',
        'HMMER_query-len' => 'RESULT-query_length',
        'HMMER_query-acc' => 'RESULT-query_accession',
        'HMMER_querydesc' => 'RESULT-query_description',
        'HMMER_hmm'       => 'RESULT-hmm_name',
        'HMMER_seqfile'   => 'RESULT-sequence_file',
        'HMMER_db'        => 'RESULT-database_name',
    );
}

=head2 new

 Title   : new
 Usage   : my $obj = new Bio::SearchIO::Hmmer3->new();
 Function: Builds a new Bio::SearchIO::Hmmer3 object
 Returns : an instance of Bio::SearchIO::Hmmer3
 Args    : -fh/-file => HMMER filename
           -format   => 'hmmer3'

=cut

sub _initialize {
  my( $self,@args ) = @_;
  $self->SUPER::_initialize(@args);
  $self->{'_hmmidline'} = 'HMMER 3.0b placeholder';
  $self->{'_alnreport'} = 1; #does report include alignments
}

=head2 next_result

 Title   : next_result
 Usage   : my $hit = $searchio->next_result;
 Function: Returns the next Result from a search
 Returns : Bio::Search::Result::ResultI object
 Args    : none

=cut

sub next_result{
   my ($self)  = @_;
   my $seentop = 0; #Placeholder for when we deal with multi-query reports
   my $reporttype;
   my ( $last, @hit_list, @hsp_list, %hspinfo, %hitinfo, %domaincounter );
   local $/ = "\n";
   local $_;

   my $verbose = $self->verbose;  # cache for speed? JES's idea in hmmer.pm
   $self->start_document();
   local ($_);
   #This is here to ensure that next_result doesn't produce infinite loop
   if(!defined( $_ = $self->_readline) ) {
       return undef;
   }
   else{
       $self->_pushback($_);
   }
   #Regex goes here for HMMER3
   #Start with hmmsearch processing
   while ( defined( $_ = $self->_readline ) ) {
       my $lineorig = $_;
       chomp;
       #Grab the program name.
       if ( $_ =~ m/^\#\s(\S+)\s\:\:\s/ ){
	   my $prog = $1;
	   #TO DO LATER: customize the above regex to adapt to other
	   #program types!!! (hmmscan, etc)
	   $self->start_element( { 'Name' => 'HMMER_Output' } );
	   $self->{'_result_count'}++; #Might need to move to another block
	   $self->element(
	       {
		   'Name' => 'HMMER_program',
		   'Data' => uc($prog)
	       }
	   );
       }
       #Get the HMMER package version and release date
       elsif ( $_ =~ m/^\#\sHMMER\s+(\S+)\s+\((.+)\)/ ) {
	   my $version     = $1;
	   my $versiondate = $2;
	   $self->{'_hmmidline'} = $_;
	   $self->element(
	       {
		   'Name' => 'HMMER_version',
		   'Data' => $version
	       }
           );
       }
       #Get the query info
       elsif( $_ =~ /^\#\squery \w+ file\:\s+(\S+)/ ){
	   if( $self->{'_reporttype'} eq 'HMMSEARCH') {
	       $self->{'_hmmfileline'} = $lineorig;
	       $self->element(
		   {
		       'Name' => 'HMMER_hmm',
		       'Data' => $1
		   }
	       );
	   }
	   elsif( $self->{'_reporttype'} eq 'HMMSCAN' ) {
	       $self->{'_hmmseqline'} = $lineorig;
	       $self->element(
		   {
		       'Name' => 'HMMER_seqfile',
		       'Data' => $1
		   }
	      );
	   }
       }
       #If this is a report without alignments
       elsif( $_ =~ m/^\#\sshow\salignments\sin\soutput/ ){
	   $self->{'_alnreport'} = 0;
       }
       #Get the database info
       elsif( $_ =~ m/^\#\starget\s\S+\sdatabase\:\s+(\S+)/ ){
#	   $self->{'_hmmseqline'} = $lineorig;
#	   $self->element(
#	       {
#		   'Name' => 'HMMER_seqfile',
#		   'Data' => $1
#	       }
#	   );
	   if( $self->{'_reporttype'} eq 'HMMSEARCH') {
	       $self->{'_hmmseqline'} = $lineorig;
	       $self->element(
		   {
		       'Name' => 'HMMER_seqfile',
		       'Data' => $1
		   }
	       );
	   }
	   elsif( $self->{'_reporttype'} eq 'HMMSCAN' ) {
	       $self->{'_hmmfileline'} = $lineorig;
	       $self->element(
		   {
		       'Name' => 'HMMER_hmm',
		       'Data' => $1
		   }
	      );
	   }
       }
       #Get query data
       elsif( $_ =~ s/^Query:\s+// ) {
           #TODO Code to deal with multi query report
	   unless( s/\s+\[[L|M]\=(\d+)\]$// ){
	       warn "Error parsing length for query, offending line $_\n";
	       exit(0);
	   }
	   my $querylen = $1;
	   $self->element(
	       {
		   'Name' => 'HMMER_query-len',
		   'Data' => $querylen
	       }
	   );
	   $self->element(
	       {
		   'Name' => 'HMMER_query-def',
		   'Data' => $_
	       }
	   );
       }
       #Get Accession data
       elsif( $_ =~ s/^Accession:\s+// ){
	   s/\s+$//;
	   $self->element(
	       {
		   'Name' => 'HMMER_query-acc',
		   'Data' => $_
	       }
	   );
       }
       #Get description data
       elsif( $_ =~ s/^Description:\s+// ){
	   s/\s+$//;
	   $self->element(
	       {
		   'Name' => 'HMMER_querydesc',
		   'Data' => $_
	       }
	   );
       }
       #PROCESS HMMSEARCH AND HMMSCAN RESULTS SPECIFIC FORMATTING HERE
       elsif( defined $self->{'_reporttype'} &&
	      (
	       $self->{'_reporttype'} eq 'HMMSEARCH' ||
	       $self->{'_reporttype'} eq 'HMMSCAN'
	      )
	   ){
	   #Complete sequence table data above inclusion threshold
	   if( $_ =~ m/Scores for complete sequence/){
	       while (defined( $_ = $self->_readline ) ) {
		   if ($_ =~ m/inclusion threshold/ || m/Domain( and alignment)? annotation for each/ ||
                       m/\[No hits detected/ || m!^//! ){
		       $self->_pushback($_);
		       last;
		   }
		   #grab table data
		   next if ( m/\-\-\-/ || m/^\s+E\-value\s+score/ || m/^$/);
		   my (
		       $eval_full, $score_full, $bias_full,
		       $eval_best, $score_best, $bias_best,
		       $exp, $n, $hitid, $desc, @hitline
		       );
                   @hitline = split(" ", $_);
                   $eval_full  = shift @hitline;
                   $score_full = shift @hitline;
                   $bias_full  = shift @hitline;
                   $eval_best  = shift @hitline;
                   $score_best = shift @hitline;
                   $bias_best  = shift @hitline;
                   $exp        = shift @hitline;
                   $n          = shift @hitline;
                   $hitid      = shift @hitline;
                   $desc       = join " ", @hitline;

		   if( !defined( $desc ) ){
		       $desc = "";
		   }
		   push @hit_list, [ $hitid, $desc, $eval_full, $score_full ];
		   $hitinfo{$hitid}= $#hit_list;
	       }
	   }
	   #Complete sequence table data below inclusion threshold
	   #not currently fully implemented
	   elsif( $_ =~ m/inclusion threshold/ ){
	       while( defined( $_ = $self->_readline ) ) {
		   if( $_ =~ m/Domain( and alignment)? annotation for each/ ||
                       m/Internal pipeline statistics summary/ ){
		       $self->_pushback($_);
		       last;
		   }
		   next if( $_ =~ m/^$/ );
		   my (
		       $eval_full, $score_full, $bias_full,
		       $eval_best, $score_best, $bias_best,
		       $exp, $n, $hitid, $desc, @hitline
		       );
                   @hitline = split(" ", $_);
                   $eval_full  = shift @hitline;
                   $score_full = shift @hitline;
                   $bias_full  = shift @hitline;
                   $eval_best  = shift @hitline;
                   $score_best = shift @hitline;
                   $bias_best  = shift @hitline;
                   $exp        = shift @hitline;
                   $n          = shift @hitline;
                   $hitid      = shift @hitline;
                   $desc       = join " ", @hitline;

		   $hitinfo{$hitid} = "below_inclusion";
	       }
	   }
	   #Domain annotation for each sequence table data
	   elsif( $_ =~ m/Domain( and alignment)? annotation for each/){
	       @hsp_list = (); #here for multi-query reports
	       my $name;

	       while( defined( $_ = $self->_readline ) ) {
 		   if ($_ =~ m/Internal pipeline statistics/ || m/\[No targets detected/ ){
		       $self->_pushback($_);
		       last;
		   }
		   if( $_ =~ m/^\>\>\s(.*?)\s+/ ) {
 		       $name = $1;
		       #skip hits below inclusion threshold
		       next if( $hitinfo{$name} eq "below_inclusion");
                       $domaincounter{$name} = 0;

		       while( defined( $_ = $self->_readline ) ) {
			   #grab table data for sequence
			   if ($_ =~ m/Internal pipeline statistics/ ||
			       $_ =~ m/^\>\>/                        ){
			       $self->_pushback($_);
			       last;
			   }
			   if ( $_ =~ m/Alignments for each domain/ ) {
			       $self->_pushback($_);
			       last;
			   }
			   if ( $_ =~ m/^\s+\#\s+score/ ||
			        $_ =~ m/^\s\-\-\-\s+/   ||
#			        $_ =~ m/^\>\>/          ||
			        $_ =~ m/^$/             ){
			       next;
			   }

#			   grab hsp data from table, push into @hsp;
			   if(
			       my ($domain_num, $score, $bias, $ceval,
				   $ieval, $hmmstart, $hmmstop,
				   $qalistart, $qalistop, $envstart,
				   $envstop, $envbound, $acc) =
			       m!^\s+(\d+)\s\!*\?*\s+       #domain num
                                   (\S+)\s+(\S+)\s+             #score, bias
                                   (\S+)\s+(\S+)\s+             #c-eval, i-eval
                                   (\d+)\s+(\d+).+?             #hmm start, stop
                                   (\d+)\s+(\d+).+?             #query start, stop
                                   (\d+)\s+(\d+).+?             #env start, stop
                                   (\S+)                        #acc
                                   \s*$!ox
			       ){
			       #keeping simple for now. let's customize later
			       my @vals = ($hmmstart, $hmmstop, $qalistart, $qalistop, $score, $ceval, '', '', '');
			       my $info = $hit_list[ $hitinfo{$name} ];
			       if( !defined $info ){
				   $self->warn(
				       "Incomplete sequence information; can't find $name, hitinfo says $hitinfo{$name}\n"
				       );
				   next;
			       }
			       $domaincounter{$name}++;
                               my $hsp_key = $name . "_" . $domaincounter{$name};
			       push @hsp_list, [ $name, @vals ];
                               $hspinfo{$hsp_key} = $#hsp_list;
			   }
			   else{
			       print "missed this line: $_\n";
			   }
		       }
		   }
		   elsif ($_ =~ m/Alignments for each domain/ ) {
		       my $domain_count = 0;
                       #line counter
                       my $count = 0;
                       # There's an optional block, so we sometimes need to
                       # count to 3, and sometimes to 4.
                       my $max_count = 3;
		       my $lastdomain;
                       my $hsp;
                       my ($hline, $midline, $qline);

		       while( defined( $_ = $self->_readline ) ) {
			   if( $_ =~ m/^\>\>/ ||
			       $_ =~ m/Internal pipeline statistics/){
			       $self->_pushback($_);
			       last;
			   }
			   elsif( $hitinfo{$name} eq "below_inclusion" ||
			           $_ =~ m/^$/ ) {
			       next;
			   }
			   elsif( $_ =~ /\s\s\=\=\sdomain\s(\d+)\s+/){
			       my $domainnum = $1;
			       $count = 0;
                               my $key = $name . "_" . $domainnum;
                               $hsp = $hsp_list[ $hspinfo{$key} ];
                               $hline = $$hsp[-3];
                               $midline = $$hsp[-2];
                               $qline = $$hsp[-1];
			       $lastdomain = $name;
			   }
                           # model data track, some reports don't have
                           elsif( $_ =~ m/\s+\S+\sCS$/ ){
			       my $modeltrack = $_;
                               $max_count++;
			       $count++;
			       next;
			   }
			   elsif( $count == $max_count - 3 ){
			       #hit sequence
			       my @data = split(" ", $_);
			       my $seq = $data[-2];
                               $hline .= $seq;
			       $count++;
			       next;
			   }
			   elsif( $count == $max_count - 2 ){
			       #conservation track
			       #storage isn't quite right - need to remove
			       #leading/lagging whitespace while preserving
			       #gap data (latter isn't done, former is)
			       $_ =~ s/^\s+//;
			       $_ =~ s/\s+$//;
                               $midline .= $_;
			       $count++;
			       next;
			   }
			   elsif( $count == $max_count - 1 ){
			       #query track
			       my @data = split(" ", $_);
			       my $seq = $data[-2];
                               $qline .= $seq;
			       $count++;
			       next;
			   }
			   elsif( $count == $max_count ){
			       #pval track
			       my $pvals = $_;
			       $count = 0;
                               $max_count = 3;
                               $$hsp[-3] = $hline;
                               $$hsp[-2] = $midline;
                               $$hsp[-1] = $qline;
			       next;
			   }
			   else{
                               print "missed $_\n";
			   }
		       }
		   }
	       }
	   }
	   elsif( m/Internal pipeline statistics/ || m!^//! ){
#	       if within hit, hsp close;
	       if ( $self->within_element('hit') ) {
		   if ( $self->within_element('hsp') ) {
		       $self->end_element( { 'Name' => 'Hsp' } );
		   }
		   $self->end_element( { 'Name' => 'Hit' } );
	       }
	       #grab summary statistics of run
	       while( defined( $_ = $self->_readline ) ) {
                   last if ( $_ =~ m/^\/\/$/ );
	       }

	       #Jason does a lot of processing of hits/hsps here;
	       while( my $hit = shift @hit_list ) {
                   my $hit_name = shift @$hit;
                   my $hit_desc = shift @$hit;
                   my $hit_signif = shift @$hit;
                   my $hit_score = shift @$hit;
                   my $num_domains = $domaincounter{$hit_name} || 0;

                   $self->start_element( { 'Name' => 'Hit' } );
                   $self->element(
                       {
                           'Name' => 'Hit_id',
                           'Data' => $hit_name
                       }
                   );
                   $self->element(
                       {
                           'Name' => 'Hit_desc',
                           'Data' => $hit_desc
                       }
                   );
                   $self->element(
                       {
                           'Name' => 'Hit_signif',
                           'Data' => $hit_signif
                       }
                   );
                   $self->element(
                       {
                           'Name' => 'Hit_score',
                           'Data' => $hit_score
                       }
                   );
                   for my $i (1..$num_domains) {
                       my $key = $hit_name . "_" . $i;
                       my $hsp = $hsp_list[ $hspinfo{$key} ];
                       if(defined $hsp) {
                           my $hsp_name = shift @$hsp;
                           $self->start_element( { 'Name' => 'Hsp' } );
                           $self->element( {
                                   'Name' => 'Hsp_identity',
                                   'Data' => 0
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_positive',
                                   'Data' => 0
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_hit-from',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_hit-to',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_query-from',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_query-to',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_score',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_evalue',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_hseq',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_midline',
                                   'Data' => shift @$hsp
                               } );
                           $self->element( {
                                   'Name' => 'Hsp_qseq',
                                   'Data' => shift @$hsp
                               } );
                           $self->end_element( { 'Name' => 'Hsp' } );
                       }
                   }
                   $self->end_element( { 'Name' => 'Hit' } );
	       }
	       @hit_list = ();
	       %hitinfo = ();
	       last;
	   }
       }
       else{
	   print "missed: $_\n";
	   $self->debug($_);
       }
       $last = $_;
   }
   $self->end_element( { 'Name' => 'HMMER_Output' } );
   my $result = $self->end_document();
   return $result;
}



=head2 start_element

 Title   : start_element
 Usage   : $eventgenerator->start_element
 Function: Handles a start event
 Returns : none
 Args    : hashref with at least 2 keys 'Data' and 'Name'

=cut

sub start_element{

    my ( $self, $data ) = @_;

    # we currently don't care about attributes
    my $nm   = $data->{'Name'};
    my $type = $MODEMAP{$nm};
    if ($type) {
        if ( $self->_eventHandler->will_handle($type) ) {
            my $func = sprintf( "start_%s", lc $type );
            $self->_eventHandler->$func( $data->{'Attributes'} );
        }
        unshift @{ $self->{'_elements'} }, $type;
    }
    if ( defined $type
        && $type eq 'result' )
    {
        $self->{'_values'} = {};
        $self->{'_result'} = undef;
    }
}

=head2 end_element

 Title   : end_element
 Usage   : $eventgeneartor->end_element
 Function: Handles and end element event
 Returns : none
 Args    : hashref with at least 2 keys 'Data' and 'Name'

=cut

sub end_element{

    my ( $self, $data ) = @_;
    my $nm   = $data->{'Name'};
    my $type = $MODEMAP{$nm};
    my $rc;

    if ( $nm eq 'HMMER_program' ) {
        if ( $self->{'_last_data'} =~ /(HMM\S+)/i ) {
            $self->{'_reporttype'} = uc $1;
        }
    }

    # Hsp are sort of weird, in that they end when another
    # object begins so have to detect this in end_element for now
    if ( $nm eq 'Hsp' ) {
        foreach (qw(Hsp_qseq Hsp_midline Hsp_hseq)) {
            my $data = $self->{'_last_hspdata'}->{$_};
            if ($data && $_ eq 'Hsp_hseq') {
                # replace hmm '.' gap symbol by '-'
                $data =~ s/\./-/g;
            }
            $self->element(
                {
                    'Name' => $_,
                    'Data' => $data
                }
            );
        }
        $self->{'_last_hspdata'} = {};
    }
    if ($type) {
        if ( $self->_eventHandler->will_handle($type) ) {
            my $func = sprintf( "end_%s", lc $type );
            $rc = $self->_eventHandler->$func( $self->{'_reporttype'},
                $self->{'_values'} );
	}
        my $lastelem = shift @{ $self->{'_elements'} };
    }
    elsif ( $MAPPING{$nm} ) {
       if ( ref( $MAPPING{$nm} ) =~ /hash/i ) {
            my $key = ( keys %{ $MAPPING{$nm} } )[0];
            $self->{'_values'}->{$key}->{ $MAPPING{$nm}->{$key} } =
              $self->{'_last_data'};
        }
        else {
            $self->{'_values'}->{ $MAPPING{$nm} } = $self->{'_last_data'};
#	    print "lastdata is " . $self->{'_last_data'} . "\n";
        }
    }
    else {
        $self->debug("unknown nm $nm, ignoring\n");
    }
    $self->{'_last_data'} = '';    # remove read data if we are at
                                   # end of an element
    $self->{'_result'} = $rc if ( defined $type && $type eq 'result' );
    return $rc;
}

=head2 element

 Title   : element
 Usage   : $eventhandler->element({'Name' => $name, 'Data' => $str});
 Function: Convienence method that calls start_element, characters, end_element
 Returns : none
 Args    : Hash ref with the keys 'Name' and 'Data'

=cut

sub element{
    my ( $self, $data ) = @_;
    $self->start_element($data);
    $self->characters($data);
    $self->end_element($data);
}

=head2 characters

 Title   : characters
 Usage   : $eventgenerator->characters($str)
 Function: Send a character events
 Returns : none
 Args    : string

=cut

sub characters{
    my ( $self, $data ) = @_;

    if (   $self->in_element('hsp')
        && $data->{'Name'} =~ /Hsp\_(qseq|hseq|midline)/o
        && defined $data->{'Data'} )
    {
        $self->{'_last_hspdata'}->{ $data->{'Name'} } .= $data->{'Data'};
    }
    return unless ( defined $data->{'Data'} && $data->{'Data'} !~ /^\s+$/o );

    $self->{'_last_data'} = $data->{'Data'};
}

=head2 within_element

 Title   : within_element
 Usage   : if( $eventgenerator->within_element( $element ) ) {}
 Function: Test if we are within a particular element
           This is different than 'in' because within can be tested for
           a whole block
 Returns : boolean
 Args    : string element name

=cut

sub within_element{
    my ( $self, $name ) = @_;
    return 0
      if ( !defined $name
        || !defined $self->{'_elements'}
        || scalar @{ $self->{'_elements'} } == 0 );
    foreach ( @{ $self->{'_elements'} } ) {
        return 1 if ( $_ eq $name );
    }
    return 0;
}

=head2 in_element

 Title   : in_element
 Usage   : if( $eventgenerator->in_element( $element ) ) {}
 Function: Test if we are in a particular element
           This is different than 'within' because 'in' only
           tests its immediate parent
 Returns : boolean
 Args    : string element name

=cut

sub in_element{
    my ( $self, $name ) = @_;
    return 0 if !defined $self->{'_elements'}->[0];
    return ( $self->{'_elements'}->[0] eq $name );
}

=head2 start_document

 Title   : start_document
 Usage   : $eventgenerator->start_document
 Function: Handle a start document event
 Returns : none
 Args    : none

=cut

sub start_document{
   my ($self) = @_;
   $self->{'_lasttype'} = '';
   $self->{'_values'}   = {};
   $self->{'_result'}   = undef;
   $self->{'_elements'} = [];
}

=head2 end_document

 Title   : end_document
 Usage   : $eventgenerator->end_document
 Function: Handles an end document event
 Returns : Bio::Search::Result::ResultI object
 Args    : none

=cut

sub end_document{
   my ($self) = @_;
   return $self->{'_result'};
}

=head2 result_count

 Title   : result_count
 Usage   : my $count = $searchio->result_count
 Function: Returns the number of results processed
 Returns : interger
 Args    : none

=cut

sub result_count{
   my $self = shift;
   return $self->{'_result_count'};
}


1;