/usr/share/a11y-profile-manager/profiles/blindness/profile.manifest is in liba11y-profile-manager-data 0.1.11-0ubuntu4.
This file is owned by root:root, with mode 0o644.
The actual contents of the file can be viewed below.
1 2 3 4 5 6 | [profile]
name=Screen reader with speech
description=This profile configures the desktop environment to best suit the use of Orca with text to speech
monitor-schema=org.gnome.desktop.a11y.applications
monitor-key=screen-reader-enabled
at-command=orca
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