t-coffee-examples 11.00.8cbe486-6 / usr / share / doc / t-coffee-examples / kinases.aln

CLUSTAL FORMAT for T-COFFEE Version_1.89, CPU=328.10 sec, SCORE=26, Nseq=522, Len=1432

DYRK1A          ----------------YEIDSLIGKGS-------FGQVVK----AYDR-- 21
DYRK1B          ----------------YEIDSLIGKGS-------FGQVVK----AYDH-- 21
DYRK2           ----------------YEVLKVIGKGS-------FGQVVK----AYDH-- 21
DYRK3           ----------------YEVLKIIGKGS-------FGQVAR----VYDH-- 21
DYRK4           ----------------YEVLETIGKGS-------FGQVAK----CLDH-- 21
HIPK1           ----------------YEVLEFLGRGT-------FGQVAK----CWKR-- 21
HIPK2           ----------------YEVLEFLGRGT-------FGQVVK----CWKR-- 21
HIPK3           ----------------YEVLDFLGRGT-------FGQVVK----CWKR-- 21
HIPK4           ----------------YDIIEVLGKGT-------FGEVAK----GWRR-- 21
PRP4            ----------------YNVYGYTGQGV-------FSNVVR----ARDNA- 22
MOK             ----------------YKAIGKIGEGT-------FSEVMK----MQSL-- 21
1A6O            ----------------YEVVRKVGRGK-------YSEVFE----GINV-- 21
1LPUA           ----------------YEVVRKVGRGK-------YSEVFE----GINV-- 21
CK2A1           ----------------YQLVRKLGRGK-------YSEVFE----AINI-- 21
CK2A1-RS        ----------------YQLVRKLGRGK-------YSEVFE----AINI-- 21
CK2A2           ----------------YQLVRKLGRGK-------YSEVFE----AINI-- 21
HSER            ----------------LKIDDDKRRDT-------IQRLRQ----C----- 18
SLOB            ----------------VEPLKDIGWRI-------RKKYFL----MK--IK 21
CDC7            ----------------FKIEDKIGEGT-------FSSVYL----ATAQLQ 23
1CSN            ----------------YKVGRRIGEGS-------FGVIFE----GTNL-- 21
CK1G1           ----------------FRVGKKIGCGN-------FGELRL----GKNL-- 21
CK1G3           ----------------FRVGKKIGCGN-------FGELRL----GKNL-- 21
CK1G2           ----------------FRVGKKIGCGN-------FGELRL----GKNL-- 21
CK1A            ----------------YKLVRKIGSGS-------FGDIYL----AINI-- 21
CK1A2           ----------------YKLVRKIGSGS-------FGDVYL----GITT-- 21
1CKJA           ----------------YRLGRKIGSGS-------FGDIYL----GTDI-- 21
CK1D            ----------------YRLGRKIGSGS-------FGDIYL----GTDI-- 21
CK1E            ----------------YRLGRKIGSGS-------FGDIYL----GANI-- 21
TTBK1           ----------------WKVLKKIGGGG-------FGEIYE----AMDL-- 21
TTBK2           ----------------WKVLRKIGGGG-------FGEIYD----ALDM-- 21
TLK1            ----------------YLLLHLLGRGG-------FSEVYK----AFDL-- 21
TLK2            ----------------YLLLHLLGRGG-------FSEVYK----AFDL-- 21
GPRK4           ----------------FRHYRVLGKGG-------FGEVCA----CQVR-- 21
GPRK6           ----------------FRQYRVLGKGG-------FGEVCA----CQVR-- 21
GPRK5           ----------------FRQYRVLGKGG-------FGEVCA----CQVR-- 21
RHOK            ----------------FLDFRVLGKGG-------FGEVSA----CQMK-- 21
GPRK7           ----------------FTEFRVLGKGG-------FGEVCA----VQVK-- 21
BARK1           ----------------FSVHRIIGRGG-------FGEVYG----CRKA-- 21
BARK2           ----------------FSVHRIIGRGG-------FGEVYG----CRKA-- 21
TTK             ----------------YSILKQIGSGG-------SSKVFQ----VLNEK- 22
RIPK1           ----------------FLESAELDSGG-------FGKVSL----CFHR-- 21
HASPIN          ----------------LQRCEKIGEGV-------FGEVFQ----TIAD-- 21
GCN2            ----------------FEELQLLGKGA-------FGAVIK----VQNKL- 22
HRI             ----------------FEELVILGKGG-------YGRVYK----VRNKL- 22
KIS             ----------------WQVQSRLGSGS-------SASVYR----VRCCG- 22
PDK1            ----------------FKFGKILGEGS-------FSTVVL----ARELA- 22
PKR             ----------------FKEIELIGSGG-------FGQVFK----AKHRI- 22
PEK             ----------------FEPIQCLGRGG-------FGVVFE----AKNKV- 22
PRPK            ----------------LSGLELVKQGA-------EARVFR----G--RF- 20
DOMAIN2_OBSCN   ----------------FAFQTQIQRGR-------FSVV--RQ--CWEKA- 22
DOMAIN2_SPEG    ----------------YTFLEEKARGR-------FGVV--RA--CRENA- 22
LMR1            ----------------LLYLKEIGRGW-------FGKVFLGE--VNSGI- 24
LMR2            ----------------LNYIQEIGNGW-------FGKVLLGE--IYTGT- 24
LMR3            ----------------LSYLQEIGSGW-------FGKVILGE--IFSDY- 24
SGK307          -------------------------------------------------- 0
STLK5           ----------------YELLTVIGKGF-------EDLMTVNL--ARYKP- 24
STLK6           ----------------YELQVEIGRGF-------DNLTSVHL--ARHTP- 24
STLK6-RS        ----------------YELQVETGRGF-------DNLTSVHL--AWHTP- 24
OBSCN           ----------------YEVKEEIGRGV-------FGFV--KR--VQHKG- 22
SPEG            ----------------YDIHQEIGRGA-------FSYL--RR--IVERS- 22
TRAD            ----------------YTELNEIGRGR-------FSIV--KK--CIHKA- 22
TRIO            ----------------YSEVAELGRGR-------FSVV--KK--CDQKG- 22
SGK223          GSTYAVKICKAPEPKTVSYCSPSVPVH-------FNIQ--QD--CGHFV- 38
SGK269          L---------------TSDKPCCEAGD-------AVYY--TA--SYAKD- 23
ALK1            ----------------VALVECVGKGR-------YGEVWR----GLWHG- 22
ALK2            ----------------ITLLECVGKGR-------YGEVWR----GSWQG- 22
IRAK4           ----------------SVGGNKMGEGG-------FGVVYK----GYVNN- 22
BMPR2           ----------------LKLLELIGRGR-------YGAVYK----GSLDE- 22
TGFBR2          ----------------IELDTLVGKGR-------FAEVYK----AKLKQN 23
ACTR2           ----------------LQLLEVKARGR-------FGCVWK----AQLLN- 22
ACTR2B          ----------------LQLLEIKARGR-------FGCVWK----AQLMN- 22
1B6CB           ----------------IVLQESIGKGR-------FGEVWR----GKWRG- 22
TGFBR1          ----------------IVLQESIGKGR-------FGEVWR----GKWRG- 22
ALK4            ----------------IVLQEIIGKGR-------FGEVWR----GRWRG- 22
ALK7            ----------------IVLQEIVGKGR-------FGEVWH----GRWCG- 22
BMPR1A          ----------------IQMVRQVGKGR-------YGEVWM----GKWRG- 22
BMPR1B          ----------------IQMVKQIGKGR-------YGEVWM----GKWRG- 22
IRAK1           ----------------FSEELKIGEGG-------FGCVYR----AVMRN- 22
IRAK2           ----------------FNQNRKISQGT-------FADVYR----GHRH-- 21
IRAK3           ----------------FHKDFLIGEGE-------IFEVYR----VEIQN- 22
MISR2           ----------------LCFSQVIREGG-------HAVVWA----GQ--L- 20
MYT1            ----------------FQRLSRLGHGS-------YGEVFK----VRSKE- 22
SBK             ----------------YELVRELGKGT-------YGKVDL----VVYKG- 22
SGK110          ----------------YHLIRKLGSGS-------YGRVLL----AQPHQ- 22
SGK069          ----------------YEEVRPLGQGR-------YGRVLL----VTHRQ- 22
SGK496          ----------------PKLGQELGRGQ-------YGVVYL----CDNWG- 22
NIK             ----------------ATHQLRLGRGS-------FGEVHR----MEDKQ- 22
SGK424          -------------------------------------------------- 0
SURTK106        ----------------SEVLEQICSGS-------CGPIFR----ANMNT- 22
IKKE            -----W--HTDDLLGQ---------GA-------TASVYK----ARNKK- 22
TBK1            -----W--LLSDILGQ---------GA-------TANVFR----GRHKK- 22
MOS             -----V--CLLQRLGA---------GG-------FGSVYK----ATY--- 20
LKB1            -----Y--LMGDLLGE---------GS-------YGKVKE----VLDSE- 22
CAMKK1          -----Y--KLQSEIGKVGLTDAYLQGA-------YGVVRL----AYNES- 31
CAMKK2          -----Y--TLKDEIGK---------GS-------YGVVKL----AYNEN- 22
PASK            -----Y--STMSPLGS---------GA-------FGFVWT----AVDKE- 22
PIM1            -----Y--QVGPLLGS---------GG-------FGSVYS----GIRVS- 22
PIM3            -----Y--QVGAVLGS---------GG-------FGTVYA----GSRIA- 22
PIM2            -----Y--RLGPLLGK---------GG-------FGTVFA----GHRLT- 22
COT             -----YRNIGSDFIPR---------GA-------FGKVYL----AQDIK- 24
SCYL2           -----F--DVGRHIASG------GNGL-------AWKIFN----GTKKS- 25
FUSED           ----------------YHVLEMIGEGS-------FGR-VY----K----- 17
ULK1            ----------------FSRKDLIGHGA-------FAV-VF----K----- 17
ULK2            ----------------YSKRDLVGHGA-------FAV-VF----R----- 17
ULK3            ----------------FILTERLGSGT-------YAT-VY----K----- 17
ULK4            ----------------FILYEEIGRGS-------KTV-VY----K----- 17
IRE1            ----------------FCPKDVLGHGA-------EGTIVY----R----- 18
IRE2            ----------------FNPKDVLGRGA-------GGTFVF----R----- 18
RNASEL          ----------------Y----KIADTS-------EGG-IY----L----- 13
MPSK1           ----------------YLFIQKLGEGG-------FSY-VD----LV---- 18
PINK1           ----------------YLIGQSIGKGC-------SAA-VY----EATMPT 22
ALK             ----------------ITLIRGLGHGA-------FGEVYE----GQVSGM 23
LTK             ----------------VTLLRALGHGA-------FGEVYE----GLVIGL 23
ROS             ----------------LTLRLLLGSGA-------FGEVYE----GTAVDI 23
IGF1R           ----------------ITMSRELGQGS-------FGMVYE----GVAKGV 23
1IR3A           ----------------ITLLRELGQGS-------FGMVYE----GNARDI 23
INSR            ----------------ITLLRELGQGS-------FGMVYE----GNARDI 23
IRR             ----------------ISIIRELGQGS-------FGMVYE----GLARGL 23
1M14A           ----------------FKKIKVLGSGA-------FGTVYK----GLWIP- 22
EGFR            ----------------FKKIKVLGSGA-------FGTVYK----GLWIP- 22
HER2/ERBB2      ----------------LRKVKVLGSGA-------FGTVYK----GIWIP- 22
HER4/ERBB4      ----------------LKRVKVLGSGA-------FGTVYK----GIWVP- 22
HER3/ERBB3      ----------------LRKLKVLGSGV-------FGTVHK----GVWIP- 22
ITK             ----------------LTFVQEIGSGQ-------FGLVHL----GYWLN- 22
TEC             ----------------LTFMRELGSGL-------FGVVRL----GKW--- 20
TXK             ----------------LAFIKEIGSGQ-------FGVVHL----GEW--- 20
BMX             ----------------ITLLKELGSGQ-------FGVVQL----GKWK-- 21
1K2PA           ----------------LTFLKELGTGQ-------FGVVKY----GKWR-- 21
BTK             ----------------LTFLKELGTGQ-------FGVVKY----GKWR-- 21
CCK4            ----------------LQPITTLGKSE-------FGEVFL----AKAQGL 23
ROR1            ----------------VRFMEELGECA-------FGKIYK----GHLYLP 23
ROR2            ----------------VRFMEELGEDR-------FGKVYK----GHLFGP 23
MUSK            ----------------IEYVRDIGEGA-------FGRVFQ----ARAPGL 23
TRKA            ----------------IVLKWELGEGA-------FGKVFL----AECHNL 23
TRKB            ----------------IVLKRELGEGA-------FGKVFL----AECYNL 23
TRKC            ----------------IVLKRELGEGA-------FGKVFL----AECYNL 23
DDR1            ----------------LRFKEKLGEGQ-------FGEVHL----CEVDSP 23
DDR2            ----------------LTFKEKLGEGQ-------FGEVHL----CEVEGM 23
RYK             ----------------ITLKDVLQEGT-------FGRIFH----GILIDE 23
JAK1            ----------------LKRIRDLGEGH-------FGKVEL----CRYDP- 22
JAK2            ----------------LKFLQQLGKGN-------FGSVEM----CRYDPL 23
JAK3            ----------------LKYISQLGKGN-------FGSVEL----CRYDPL 23
ACK             ----------------LRLLEKLGDGS-------FGVVRR----GEWDAP 23
TYK2            ----------------LKKIRDLGEGH-------FGKVSL----YCYDPT 23
TNK1            ----------------VCRGELLGSGC-------FGVVHR----GLWTL- 22
EPHA1           ----------------LMVDTVIGEGE-------FGEVYR----GTLRLP 23
EPHA10          ----------------VTLERSLGGGR-------FGELCC----GCLQLP 23
FAK             ----------------IELGRCIGEGQ-------FGDVHQ----GIYMSP 23
EPHB6           ----------------IKIEEVIGTGS-------FGEVRQ----GRLQPR 23
EPHA2           ----------------VTRQKVIGAGE-------FGEVYK----GMLKTS 23
EPHA8           ----------------IHIEKIIGSGD-------SGEVCY----GRLRVP 23
EPHA6           ----------------IRIERVIGAGE-------FGEVCS----GRLKTP 23
EPHB1           ----------------VKIEEVIGAGE-------FGEVYK----GRLKLP 23
EPHB2           ----------------VKIEQVIGAGE-------FGEVCS----GHLKLP 23
EPHB3           ----------------VKIEEVIGAGE-------FGEVCR----GRLKQP 23
EPHB4           ----------------VKIEEVIGAGE-------FGEVCR----GRLKAP 23
EPHA7           ----------------IKIERVIGAGE-------FGEVCS----GRLKLP 23
EPHA4           ----------------IKIEKVIGVGE-------FGEVCS----GRLKVP 23
EPHA3           ----------------ISIDKVVGAGE-------FGEVCS----GRLKLP 23
EPHA5           ----------------ITIERVIGAGE-------FGEVCS----GRLKLP 23
PYK2            ----------------VVLNRILGEGL-------FGEVYE----GVYTNH 23
CSK             ----------------LKLLQTIGKGE-------FGDVML----GDYRG- 22
CTK             ----------------LTLGAQIGEGE-------FGAVLQ----GEYLG- 22
1IEPA           ----------------ITMKHKLGGGQ-------YGEVYE----GVWKK- 22
ABL             ----------------ITMKHKLGGGQ-------YGEVYE----GVWKK- 22
ARG             ----------------ITMKHKLGGGQ-------YGEVYV----GVWKK- 22
BRK             ----------------FTLCRKLGSGY-------FGEVFE----GLWKD- 22
SRM             ----------------FALGRKLGEGY-------FGEVWE----GLWLG- 22
FRK             ----------------IQLLKRLGSGQ-------FGEVWE----GLWNN- 22
FGR             ----------------ITLERRLGTGC-------FGDVWL----GTWNG- 22
FYN             ----------------LQLIKRLGNGQ-------FGEVWM----GTWNG- 22
SRC             ----------------LRLEVKLGQGC-------FGEVWM----GTWNG- 22
YES             ----------------LRLEVKLGQGC-------FGEVWM----GTWNG- 22
HCK             ----------------LKLEKKLGAGQ-------FGEVWM----ATYNK- 22
LYN             ----------------IKLVKRLGAGQ-------FGEVWM----GYYNN- 22
3LCK            ----------------LKLVERLGAGQ-------FGEVWM----GYYNG- 22
LCK             ----------------LKLVERLGAGQ-------FGEVWM----GYYNG- 22
BLK             ----------------LRLVRKLGSGQ-------FGEVWM----GYYKN- 22
FER             ----------------VILGELLGKGN-------FGEVYK----GTLKD- 22
FES             ----------------LVLGEQIGRGN-------FGEVFS----GRLRA- 22
SYK             ----------------TLEDKELGSGN-------FGTVKK----GYYQMK 23
ZAP70           ----------------LIADIELGCGN-------FGSVRQ----GVYRMR 23
FGFR1           ----------------LVLGKPLGEGC-------FGQVVL----AEAIGL 23
FGFR2           ----------------LTLGKPLGEGC-------FGQVVM----AEAVGI 23
FGFR3           ----------------LTLGKPLGEGC-------FGQVVM----AEAIGI 23
FGFR4           ----------------LVLGKPLGEGC-------FGQVVR----AEAFGM 23
RET             ----------------LVLGKTLGEGE-------FGKVVK----ATAFHL 23
TIE1            ----------------ITFEDLIGEGN-------FGQVIR----AM---I 20
1FVRA           ----------------IKFQDVIGEGN-------FGQVLK----AR---I 20
TIE2            ----------------IKFQDVIGEGN-------FGQVLK----AR---I 20
FLT1            ----------------LKLGKSLGRGA-------FGKVVQ----ASAFGI 23
KDR             ----------------LKLGKPLGRGA-------FGQVIE----ADAFGI 23
KDR_AVE         ----------------LKLGKPLGRGA-------FGQVIE----ADAFGI 23
FLT4            ----------------LHLGRVLGYGA-------FGKVVE----ASAFGI 23
FMS             ----------------LQFGKTLGAGA-------FGKVVE----ATAFGL 23
FLT3            ----------------LEFGKVLGSGA-------FGKVMN----ATAYGI 23
KIT             ----------------LSFGKTLGAGA-------FGKVVE----ATAYGL 23
PDGFRA          ----------------LVLGRVLGSGA-------FGKVVE----GTAYGL 23
PDGFRB          ----------------LVLGRTLGSGA-------FGQVVE----ATAHGL 23
MER             ----------------LILGKILGEGE-------FGSVME----GNLK-- 21
AXL             ----------------VALGKTLGEGE-------FGAVME----GQ---L 20
TYRO3           ----------------FTLGRMLGKGE-------FGSVRE----AQLK-- 21
MET             ----------------VHFNEVIGRGH-------FGCVYH----GTL--L 21
RON             ----------------THSDRVIGKGH-------FGVVYH----GEY--I 21
HH498           ----------------IEFHEIIGSG-------SFGKVYK--------GR 19
LZK             ----------------ISELQWLGSG-------AQGAVFL--------GK 19
DLK             ----------------ILDLQWVGSG-------AQGAVFL--------GR 19
MLK1            ----------------LTLEEIIGIG-------GFGKVYR--------AF 19
MLK3            ----------------LRLEEVIGIG-------GFGKVYR--------GS 19
MLK2            ----------------LQLEEIIGVG-------GFGKVYR--------AL 19
MLK4            ----------------LELKELIGAG-------GFGQVYR--------AT 19
ZAK             ----------------LQFFENCGGG-------SFGSVYR--------AK 19
TAK1            ----------------IEVEEVVGRG-------AFGVVCK--------AK 19
KSR1            ----------------VELGEPIGQG-------RWGRVHR--------GR 19
KSR2            ----------------LEIGELIGKG-------RFGQVYH--------GR 19
ARAF            ----------------VQLLKRIGTG-------SFGTVFR--------GR 19
RAF1            ----------------VMLSTRIGSG-------SFGTVYK--------GK 19
BRAF            ----------------ITVGQRIGSG-------SFGTVYK--------GK 19
LRRK2           ----------------TVHGADHGDG-------SFGSVYR--------AA 19
ANKRD3          ----------------FTGWEKVGSG-------GFGQVYK--------VR 19
SGK288          -------------------WRLVASG-------GFSQVFQ--------AR 16
RIPK2           ----------------LADLRYLSRG-------ASGTVSS--------AR 19
RIPK3           ----------------LENQELVGKD-------GFGTVFR--------AQ 19
MLKL            ---------------------LLREN-------EVSTLYK--------GE 14
ANPA            -------------GRGSNYGSLLTTE-GQFQ------------VFAKTAY 24
ANPB            -------------LRGSSYGSLMTAH-GKYQ------------IFANTGH 24
CYGD            ----------------ARSMSDIRSGPSQHL------------DSPNIGV 22
CYGF            ----------------FQITSEVQSGRSPRLSFSSGSLTPATYENSNIAI 34
TBCK            ------------------ALPHDVCGS-------NGLPLTP--------- 16
ERK1            ---------------Y-TQLQYIGEGA-------YGMVSS----AY--DH 21
3ERK            ---------------Y-TNLSYIGEGA-------YGMVCS----AY--DN 21
ERK2            ---------------Y-TNLSYIGEGA-------YGMVCS----AY--DN 21
ERK5            ---------------Y-EIIETIGNGA-------YGVVSS----AR--RR 21
1JNK            ---------------Y-QNLKPIGSGA-------QGIVCA----AY--DA 21
1PMNA           ---------------Y-QNLKPIGSGA-------QGIVCA----AY--DA 21
JNK3            ---------------Y-QNLKPIGSGA-------QGIVCA----AY--DA 21
JNK1            ---------------Y-QNLKPIGSGA-------QGIVCA----AY--DA 21
JNK2            ---------------Y-QQLKPIGSGA-------QGIVCA----AF--DT 21
1P38            ---------------Y-QNLSPVGSGA-------YGSVCA----AF--DT 21
P38A            ---------------Y-QNLSPVGSGA-------YGSVCA----AF--DT 21
P38B            ---------------L-QGLRPVGSGA-------YGSVCS----AY--DA 21
P38D            ---------------Y-VSPTHVGSGA-------YGSVCS----AI--DK 21
P38G            ---------------Y-RDLQPVGSGA-------YGAVCS----AV--DG 21
NLK             ---------------I-EPDRPIGYGA-------FGVVWS----VT--DP 21
ERK7            ---------------Y-LLRRQLGQGA-------YGIVWK----AV--DR 21
ERK3            ---------------Y-MDLKPLGCGG-------NGLVFS----AV--DN 21
ERK4            ---------------F-VDFQPLGFGV-------NGLVLS----AV--DS 21
ICK             ---------------Y-TTIRQLGDGT-------YGSVLL----GR--SI 21
MAK             ---------------Y-TTMRQLGDGT-------YGSVLM----GK--SN 21
PCTAIRE1        ---------------Y-IKLDKLGEGT-------YATVYK----GK--SK 21
PCTAIRE2        ---------------Y-IKLEKLGEGT-------YATVYK----GR--SK 21
PCTAIRE3        ---------------Y-VKLDKLGEGT-------YATVFK----GR--SK 21
PFTAIRE1        ---------------Y-EKLEKLGEGS-------YATVYK----GK--SK 21
PFTAIRE2        ---------------Y-LNLEKLGEGS-------YATVYK----GI--SR 21
CDC2            ---------------Y-TKIEKIGEGT-------YGVVYK----GR--HK 21
1HCL            ---------------F-QKVEKIGEGT-------YGVVYK----AR--NK 21
CDK2            ---------------F-QKVEKIGEGT-------YGVVYK----AR--NK 21
CDK3            ---------------F-QKVEKIGEGT-------YGVVYK----AK--NR 21
CDK5            ---------------Y-EKLEKIGEGT-------YGTVFK----AK--NR 21
CDK7            ---------------Y-EKLDFLGEGQ-------FATVYK----AR--DK 21
CDK4            ---------------Y-EPVAEIGVGA-------YGTVYK----AR--DP 21
1BLXA           ---------------Y-ECVAEIGEGA-------YGKVFK----AR--DL 21
CDK6            ---------------Y-ECVAEIGEGA-------YGKVFK----AR--DL 21
PITSLRE         ---------------F-QCLNRIEEGT-------YGVVYR----AK--DK 21
CDK10           ---------------F-EKLNRIGEGT-------YGIVYR----AR--DT 21
CDK9            ---------------Y-EKLAKIGQGT-------FGEVFK----AR--HR 21
CHED            ---------------F-DIIGIIGEGT-------YGQVYK----AR--DK 21
CRK7            ---------------F-DIIGIIGEGT-------YGQVYK----AR--DK 21
CCRK            ---------------Y-CILGRIGEGA-------HGIVFK----AK--HV 21
CDK11           ---------------FEYEGCKVGRGT-------YGHVYK----ARRKDG 24
CDK8            ---------------FEYEGCKVGRGT-------YGHVYK----AKRKDG 24
IKKA            ----------------WEMRERLGTGG-------FGNVCLY---Q-HRE- 22
IKKB            ----------------WEMKERLGTGG-------FGNVIRW---H-NQE- 22
1PHK            ----------------YEPKEILGRGV-------SSVVRRC---I-HKP- 22
PHKG1           ----------------YEPKEILGRGV-------SSVVRRC---I-HKP- 22
PHKG2           ----------------YDPKDVIGRGV-------SSVVRRC---V-HRA- 22
CAMK2A          ----------------YQLFEELGKGA-------FSVVRRC---V-KVL- 22
CAMK2B          ----------------YQLYEDIGKGA-------FSVVRRC---V-KLC- 22
CAMK2G          ----------------YQLFEELGKGA-------FSVVRRC---V-KKT- 22
CAMK2D          ----------------YQLFEELGKGA-------FSVVRRC---M-KIP- 22
CASK            ----------------YELCEVIGKGP-------FSVVRRC---I-NRE- 22
1IA8A           ----------------WDLVQTLGEGA-------YGEVQLA---V-NRV- 22
CHK1            ----------------WDLVQTLGEGA-------YGEVQLA---V-NRV- 22
CLK1            ----------------YEIVDTLGEGA-------FGKVVEC---IDHKA- 23
CLK4            -----------------EIVDTLGEGA-------FGKVVEC---IDHGM- 22
CLK2            ----------------YEIVSTLGEGT-------FGRVVQC---VDHRR- 23
CLK3            ----------------YEIVGNLGEGT-------FGKVVEC---LDHAR- 23
MAP2K5          ----------------IRYRDTLGHGN-------GGTVYK----AYHVP- 22
MAP2K3          ----------------LVTISELGRGA-------YGVVEK----VRHAQ- 22
MAP2K6          ----------------LEPIMELGRGA-------YGVVEK----MRHVP- 22
MAP2K4          ----------------LKDLGEIGRGA-------YGSVNK----MVHKP- 22
MAP2K7          ----------------LENLGEMGSGT-------CGQVWK----MRFRK- 22
MAP2K1          ----------------FEKISELGAGN-------GGVVFK----VSHKP- 22
MAP2K2          ----------------FERISELGAGN-------GGVVTK----VQHRP- 22
CDKL5           ----------------FEILGVVGEGA-------YGVVLK----CRHKE- 22
CDKL1           ----------------YEKIGKIGEGS-------YGVVFK----CRNRD- 22
CDKL4           ----------------YEKLAKTGEGS-------YGVVFK----CRNKT- 22
CDKL2           ----------------YENLGLVGEGS-------YGMVMK----CRNKD- 22
CDKL3           ----------------YETLGKVGEGS-------YGTVMK----CKHKN- 22
1I09B           ----------------YTDTKVIGNGS-------FGVVYQ----AKLCD- 22
GSK3B           ----------------YTDTKVIGNGS-------FGVVYQ----AKLCD- 22
1J1BA           ----------------YTDTKVIGNGS-------FGVVYQ----AKLCD- 22
GSK3A           ----------------YTDIKVIGNGS-------FGVVYQ----ARLAE- 22
LATS1           ----------------FVKIKTLGIGA-------FGEVCL----ARKVD- 22
LATS2           ----------------FVKIKTLGIGA-------FGEVCL----ACKVD- 22
NDR1            ----------------FESLKVIGRGA-------FGEVRL----VQKKD- 22
NDR2            ----------------FESLKVIGRGA-------FGEVRL----VQKKD- 22
MAST1           ----------------FDTIKLISNGA-------YGAVYL----VRHRD- 22
MAST4           ----------------FETIKLISNGA-------YGAVYF----VRHKE- 22
MAST2           ----------------FETIKLISNGA-------YGAVFL----VRHKS- 22
MAST3           ----------------FETIKLISNGA-------YGAVYL----VRHRD- 22
MRCKA           ----------------FEILKVIGRGA-------FGEVAV----VKLKN- 22
MRCKB           ----------------FEIIKVIGRGA-------FGEVAV----VKMKN- 22
DMPK2           ----------------FEILKVIGRGA-------FGEVTV----VRQRD- 22
DMPK1           ----------------FEILKVIGRGA-------FSEVAV----VKMKQ- 22
ROCK1           ----------------YEVVKVIGRGA-------FGEVQL----VRHKS- 22
ROCK2           ----------------YDVVKVIGRGA-------FGEVQL----VRHKA- 22
CRIK            ----------------FEVRSLVGCGH-------FAEVQV----VREKA- 22
MASTL           ----------------FSIVKPISRGA-------FGKVYL----GQK--- 20
1O6LA           ----------------FDYLKLLGKGT-------FGKVIL----VRE--- 20
AKT2            ----------------FDYLKLLGKGT-------FGKVIL----VRE--- 20
AKT1            ----------------FEYLKLLGKGT-------FGKVIL----VKE--- 20
AKT3            ----------------FDYLKLLGKGT-------FGKVIL----VRE--- 20
MSK1            ----------------FELLKVLGTGA-------YGKVFL----VRKISG 23
MSK2            ----------------FELLKVLGTGA-------YGKVFL----VRKAGG 23
P70S6K          ----------------FELLRVLGKGG-------YGKVFQ----VRKVTG 23
P70S6KB         ----------------FELLRVLGKGG-------YGKVFQ----VRKVQG 23
RSK1            ----------------FELLKVLGQGS-------YGKVFL----VRKVKG 23
RSK3            ----------------FELLKVLGQGS-------FGKVFL----VRKVTR 23
RSK2            ----------------FELLKVLGQGS-------FGKVFL----VKKISG 23
RSK4            ----------------FELLKVLGQGS-------FGKVFL----VRKKTG 23
1FOTA           ----------------FQILRTLGTGS-------FGRVHL----IRS--- 20
1CDKA           ----------------FERIKTLGTGS-------FGRVML----VKH--- 20
PKACA           ----------------FERIKTLGTGS-------FGRVML----VKH--- 20
PKACB           ----------------FERKKTLGTGS-------FGRVML----VKH--- 20
PKACG           ----------------FERLRTLGMGS-------FGRVML----VRH--- 20
PRKX            ----------------FDTLATVGTGT-------FGRVHL----VKE--- 20
PRKY            ----------------CDALVTMGTGT-------FGRVHL----VKE--- 20
PKCA            ----------------FNFLMVLGKGS-------FGKVML----ADR--- 20
PKCB            ----------------FNFLMVLGKGS-------FGKVML----SER--- 20
PKCG            ----------------FSFLMVLGKGS-------FGKVML----AER--- 20
PKCE            ----------------FNFIKVLGKGS-------FGKVML----AEL--- 20
PKCH            ----------------FEFIRVLGKGS-------FGKVML----ARV--- 20
PKCD            ----------------FIFHKVLGKGS-------FGKVLL----GEL--- 20
PKCT            ----------------FILHKMLGKGS-------FGKVFL----AEF--- 20
PKCI            ----------------FDLLRVIGRGS-------YAKVLL----VRL--- 20
PKCZ            ----------------FDLIRVIGRGS-------YAKVLL----VRL--- 20
PKN1            ----------------FKFLAVLGRGH-------FGKVLL----SEF--- 20
PKN2            ----------------FRCCAVLGRGH-------FGKVLL----AEY--- 20
PKN3            ----------------FRCLAVLGRGH-------FGKVLL----VQF--- 20
SGK             ----------------FHFLKVIGKGS-------FGKVLL----ARH--- 20
SGK2            ----------------FDFLKVIGKGN-------YGKVLL----AKR--- 20
SGK3            ----------------FDFLKVIGKGS-------FGKVLL----AKR--- 20
PKG1            ----------------FNIIDTLGVGG-------FGRVEL----VQL--- 20
PKG2            ----------------LEIIATLGVGG-------FGRVEL----VKV--- 20
AURB            ----------------FEIGRPLGKGK-------FGNVYL----AREKK- 22
AURC            ----------------FEIGRPLGKGK-------FGNVYL----ARLKE- 22
AURA            ----------------FEIGRPLGKGK-------FGNVYL----AREKQ- 22
AURORA2_AVE     ----------------FEIGRPLGKGK-------FGNVYL----AREKQ- 22
PLK1            ----------------YVRGRLLSKGG-------FAKCFE----ISDAD- 22
PLK2            ----------------YCRGKVLGKGG-------FAKCYE----MTDLT- 22
PLK3            ----------------YLKGRLLGKGG-------FARCYE----ATDTE- 22
PLK4            ----------------FKVGNLLGKGS-------FAGVYR----AESIH- 22
NEK11           ----------------YVLQQKLGSGS-------FGTVYL----VSDKK- 22
YANK1           ----------------FEILRAIGKGS-------FGKVCI----VQKND- 22
YANK2           ----------------FQILRAIGKGS-------FGKVCI----VQKRD- 22
YANK3           ----------------FQILRAIGKGS-------FGKVCI----VQKRD- 22
SGK494          ----------------LKILGLVAKGS-------FGTVLK----VLDCT- 22
DOMAIN2_MSK1    ----------------DLKDKPLGEGS-------FSICRK----CVHKK- 22
DOMAIN2_MSK2    ----------------------LGQGS-------FSVCRR----CRQRQ- 16
DOMAIN2_RSK1    ----------------YEIKEDIGVGS-------YSVCKR----CVHKA- 22
DOMAIN2_RSK2    ----------------YEVKEDIGVGS-------YSVCKR----CIHKA- 22
DOMAIN2_RSK3    ----------------YVVKETIGVGS-------YSECKR----CVHKA- 22
DOMAIN2_RSK4    ----------------YELKEDIGVGS-------YSVCKR----CIHAT- 22
DRAK1           ----------------LCPGRELGRGK-------FAVVRK----CIKKD- 22
DRAK2           ----------------ILTSKELGRGK-------FAVVRQ----CISKS- 22
1JKSA           ----------------YDTGEELGSGQ-------FAVVKK----CREKS- 22
DAPK1           ----------------YDTGEELGSGQ-------FAVVKK----CREKS- 22
DAPK3           ----------------YEMGEELGSGQ-------FAIVRK----CRQKG- 22
DAPK2           ----------------YDIGEELGSGQ-------FAIVKK----CREKS- 22
SGK085          ----------------VSKTEILGGGR-------FGQVHK----CEETA- 22
CAMLCK          ----------------VCQHEVLGGGR-------FGQVHR----CTEKS- 22
SKMLCK          ----------------MNSKEALGGGK-------FGAVCT----CMEKA- 22
SMMLCK          ----------------YDIEERLGSGK-------FGQVFR----LVEKK- 22
1KOBA           ----------------YDILEELGSGA-------FGVVHR----CVEKA- 22
1TKIA           ----------------YMIAEDLGRGE-------FGIVHR----CVETS- 22
TTN             ----------------YMIAEDLGRGE-------FGIVHR----CVETS- 22
PKD1            ----------------IFPDEVLGSGQ-------FGIVYG----GKHRK- 22
PKD3            ----------------IFADEVLGSGQ-------FGIVYG----GKHRK- 22
PKD2            ----------------IFPDEVLGSGQ-------FGVVYG----GKHRK- 22
PSKH1           ----------------YDIKALIGRGS-------FSRVVR----VEHRA- 22
PSKH2           ----------------YDIKALIGTGS-------FSRVVR----VEQKT- 22
CAMK1A          ----------------YDFRDVLGTGA-------FSEVIL----AEDKR- 22
CAMK1D          ----------------FEFKETLGTGA-------FSEVVL----AEEKA- 22
CAMK1B          ----------------YEIRERLGSGA-------FSEVVL----AQERG- 22
CAMK1G          ----------------FIFMEVLGSGA-------FSEVFL----VKQRL- 22
CAMK4           ----------------FEVESELGRGA-------TSIVYR----CKQKG- 22
DCAMKL1         ----------------YKVGRTIGDGN-------FAVVKE----CVERS- 22
DCAMKL2         ----------------YKIGKVIGDGN-------FAVVKE----CIDRS- 22
DCAMKL3         ----------------YETGRVIGDGN-------FAVVKE----CRHRE- 22
CHK2            ----------------YIMSKTLGSGA-------CGEVKL----AFERK- 22
MAPKAPK2        ----------------KVTSQVLGLGI-------NGKVLQ----IFNKR- 22
MAPKAPK3        ----------------QLSKQVLGLGV-------NGKVLE----CFHRR- 22
MAPKAPK5        ----------------INWTQKLGAGI-------SGPVRV----CVKKS- 22
MNK1            ---------------YKLTSELLGEGA-------YAKVQG----AVSLQ- 23
MNK2            ----------------QLQEDVLGEGA-------HARVQT----CINLI- 22
VACAMKL         ----------------YDLGQVIKTEE-------FCEIFR----AKDKT- 22
GCK             -----------FEL-----LQRVGAGT-------YGDVYK----ARDTV- 22
KHS1            -----------YEL-----VQRVGSGT-------YGDVYK----ARNVH- 22
KHS2            -----------FEL-----IQRIGSGT-------YGDVYK----ARNVN- 22
HPK1            -----------YDL-----LQRLGGGT-------YGEVFK----ARDKV- 22
MST1            -----------FDV-----LEKLGEGS-------YGSVYK----AIHKE- 22
MST2            -----------FDV-----LEKLGEGS-------YGSVFK----AIHKE- 22
MST3            -----------FTK-----LEKIGKGS-------FGEVFK----GIDNR- 22
YSK1            -----------FTK-----LDRIGKGS-------FGEVYK----GIDNH- 22
MST4            -----------FTK-----LQRIGKGS-------FGEVFK----GIDNR- 22
LOK             -----------WEI-----VGELGDGA-------FGKVYK----AKNKE- 22
SLK             -----------WEI-----IGELGDGA-------FGKVYK----AQNKE- 22
MAP3K4          -----------WQR-----GNKIGEGQ-------YGKVYT----CISVD- 22
MAP3K2          -----------WRL-----GKLLGQGA-------FGRVYL----CYDVD- 22
MAP3K3          -----------WRR-----GKLLGQGA-------FGRVYL----CYDVD- 22
MAP3K8          -----------WTK-----GEILGKGA-------YGTVYC----GLTSQ- 22
MAP3K5          -----------YEYDENGDRVVLGKGT-------YGIVYA----GRDLS- 27
MAP3K7          ------------------ERVVLGKGT-------YGIVYA----GRDLS- 20
MAP3K6          ---------------------VLGKGT-------YGVVYA----GRDRH- 17
PAK1            -----------YTR-----FEKIGQGA-------SGTVYT----AMDVA- 22
PAK3            -----------YTR-----FEKIGQGA-------SGTVYT----ALDIA- 22
PAK2            -----------YTR-----YEKIGQGA-------SGTVFT----ATDVA- 22
PAK4            -----------LDN-----FIKIGEGS-------TGIVCI----ATVRS- 22
PAK5            -----------LAN-----FIKIGEGS-------TGIVCI----ATEKH- 22
PAK6            -----------LDS-----YVKIGEGS-------TGIVCL----AREKH- 22
OSR1            -----------YEL-----QEVIGSGA-------TAVVQA----AYCAP- 22
STLK3           -----------YEL-----QEVIGSGA-------TAVVQA----ALCKP- 22
TAO1            -----------FTD-----LREIGHGS-------FGAVYF----ARDVR- 22
TAO3            -----------FIG-----LHEIGHGS-------FGAVYF----ATNAH- 22
TAO2            -----------FSD-----LREIGHGS-------FGAVYF----ARDVR- 22
MYO3A           -----------WEI-----TETIGKGT-------YGKVFK----VLNKK- 22
MYO3B           -----------WEI-----IETIGKGT-------YGKVYK----VTNKR- 22
ZC1/HGK         -----------FEL-----VEVVGNGT-------YGQVYK----GRHVK- 22
ZC3/MINK        -----------FEL-----VEVVGNGT-------YGQVYK----GRHVK- 22
ZC2/TNIK        -----------FEL-----VELVGNGT-------YGQVYK----GRHVK- 22
ZC4/NRK         -----------FSL-----DKTIGLGT-------YGRIYL----GLHEK- 22
MAP3K1          -----------WLK-----GQQIGLGA-------FSSCYQ----AQDVG- 22
GAK             ---------------LRVR-RVLAEGG-------FAFVYE----AQDVG- 22
SGK495          -------------------------------------------------- 0
TRB1            ------------------------LAE-------REHVSR----ALCIH- 14
TRB2            ---------------YLLL-EPLE----------GDHVFR----AVHLH- 19
TRB3            ---------------------LLEPEE-------GGRAYQ----ALHCP- 17
SSTK            ---------------YKLG-RTIGEGS-------YSKVKV----ATSKK- 22
TSSK3           ---------------YQLG-KTIGEGT-------YSKVKE----AFSKK- 22
TSSK1           ---------------YLLG-INLGEGS-------YAKVKS----AYSER- 22
TSSK2           ---------------YIVG-INLGKGS-------YAKVKS----AYSER- 22
TSSK4           ---------------YEVG-KAIGHGS-------YGSVYE----AFYTK- 22
HUNK            ---------------YLIGSRKLGEGS-------FAKVRE----GLHVL- 23
SNRK            ---------------YDLD-KTLGRGH-------FACGTC----SRHVF- 22
NIM1            ---------------YRIR-GEIGSGN-------FSQVKL----GIHSL- 22
MELK            ---------------YELH-ETIGTGG-------FAKVKL----ACHIL- 22
BRSK1           ---------------YRLE-KTLGKGQ-------TGLVKL----GVHCI- 22
BRSK2           ---------------YRLE-KTLGKGQ-------TGLVKL----GVHCV- 22
MARK1           ---------------YRLQ-KTIGKGN-------FAKVKL----ARHVL- 22
MARK2           ---------------YRLL-KTIGKGN-------FAKVKL----ARHIL- 22
MARK3           ---------------YRLL-KTIGKGN-------FAKVKL----ARHIL- 22
MARK4           ---------------YRLL-RTIGKGN-------FAKVKL----ARHIL- 22
QIK             ---------------YDIE-GTLGKGN-------FAVVKL----GRHRI- 22
SIK             ---------------YDIE-RTLGKGN-------FAVVKL----ARHRV- 22
QSK             ---------------YEID-RTIGKGN-------FAVVKR----ATHLV- 22
AMPKA1          ---------------YILG-DTLGVGT-------FGKVKV----GKHEL- 22
AMPKA2          ---------------YVLG-DTLGVGT-------FGKVKI----GEHQL- 22
NUAK1           ---------------YELQ-ETLGKGT-------YGKVKR----ATERF- 22
NUAK2           ---------------YEFL-ETLGKGT-------YGKVKK----ARES-- 21
BIKE            ---------------VTLE-ESLAEGG-------FSTVFL----VR-TH- 21
AAK1            ---------------VTVD-EVLAEGG-------FAIVFL----VR-TS- 21
LIMK1           ----------------LIHGEVLGKGC-------FGQAIK----VTHRE- 22
LIMK2           ----------------LIHGEVLGKGF-------FGQAIK----VTHKA- 22
TESK1           ----------------FHCAEKIGAGF-------FSEVYK----VRHRQ- 22
TESK2           --------------------EKIGSGF-------FSEVFK----VRHRA- 18
WNK1            ----------------LKFDIEIGRGS-------FKTVYK----GLDTE- 22
WNK3            ----------------LKFDIELGRGA-------FKTVYK----GLDTE- 22
WNK2            ----------------LKFDIELGRGS-------FKTVYK----GLDTE- 22
WNK4            ----------------LKFDIEIGRGS-------FKTVYR----GLDTD- 22
NEK10           ----------------YAILDHLGSGA-------FGCVYK----VRKHS- 22
NEK6            ----------------FQIEKKIGRGQ-------FSEVYK----ATCLL- 22
NEK7            ----------------FRIEKKIGRGQ-------FSEVYR----AACLL- 22
NEK2            ----------------YEVLYTIGTGS-------YGRCQK----IRRKS- 22
NEK1            ----------------YVRLQKIGEGS-------FGKAIL----VKSTE- 22
NEK5            ----------------YDVIKAIGQGA-------FGKAYL----AKGKS- 22
NEK3            ----------------YMVLRMIGEGS-------FGRALL----VQHES- 22
NEK4            ----------------YCYLRVVGKGS-------YGEVTL----VKHRR- 22
NEK8            ----------------YERIRVVGRGA-------FGIVHL----CLRKA- 22
NEK9            ----------------YIPIRVLGRGA-------FGEATL----YRRTE- 22
NRBP1           ----------------QKRREEVNQRNVP----GIDSAYL----AMDTE- 25
NRBP2           ----------------QKRREQVNQGNMP----GLQSTFL----AMDTE- 25
CLIK1           ----------------YSLLAEIGRGS-------YGVVYE----AVAGR- 22
CLIK1L          ----------------YDLIREVGRGS-------YGVVYE----AVIRK- 22
STK33           ----------------YTFGRILGKGS-------FGIVIE----ATDKE- 22
DOMAIN2_GCN2    ----------------VHKGKCIGSDE-------Q-------------LG 14
SCYL1           --------------WALHRGRKKATGS-------PVSIFV---------- 19
SCYL3           ----------------AVYPAVLQDGK-------FASVFV---------- 17
DOMAIN2_JAK1    ----------------LVQGEHLGRGT-------RTHIYS---------- 17
DOMAIN2_TYK2    ----------------ITQLSHLGQGT-------RTNVYE---------- 17
DOMAIN2_JAK2    ----------------LIFNESLGQGT-------FTKIFK---------- 17
DOMAIN2_JAK3    ----------------LEWHENLGHGS-------FTKIYR---------- 17
ILK             ----------------LNFLTKLNENH-------SGELWK---------- 17
LRRK1           ----------------EDEGSVLGQGG-------SGTVIY---------- 17
PBK             ----------------SPFMQKLGFGT-------GVNVYL---------- 17
WEE1            ----------------FHELEKIGSGE-------FGSVFK---------- 17
WEE1B           ----------------FLEVEKIGVGE-------FGTVYK---------- 17
SGK071          ----------------YQVLYQLNPGA-------LGVNLV---------- 17
PIK3R4          ----------------FEYDKSLGSTR-------FFKVAR---------- 17
MSSK1           ----------------YHVVRKLGWGH-------FSTVWL---------- 17
SRPK1           ----------------YHVIRKLGWGH-------FSTVWL---------- 17
SRPK2           ----------------YHVIRKLGWGH-------FSTVWL---------- 17
RSKL1           ---------------------------------------C----SPLSGA 7
RSKL2           ----------CRVVGVIEKVQLVQ--------------------DPATGG 20
SGK396          -------------------AEPMKELS-------SKRPLV---------- 14
VRK1            ----------------WKVGLPIGQGG-------FGCIYL---------- 17
VRK2            ----------------WVLGKKIGSGG-------FGLIYL---------- 17
VRK3            -------------------------------------------------- 0
BUB1            ----------------VYVHHLLGEGA-------FAQVYE---------- 17
BUBR1           ----------------LEIEKEIELGN-------EDYCIK---------- 17
SGK196          ----------------VRQLKRVGEGA-------VKRVFL---------- 17
SGK493          -------------------AQYMGSGY-------TKAVYR---------- 14
                                                                  

DYRK1A          --VEQ-----------------------------EW--VAIKIIK-NKKA 37
DYRK1B          --QTQ-----------------------------EL--VAIKIIK-NKKA 37
DYRK2           --KVH-----------------------------QH--VALKMVR-NEKR 37
DYRK3           --KLR-----------------------------QY--VALKMVR-NEKR 37
DYRK4           --KNN-----------------------------EL--VALKIIR-NKKR 37
HIPK1           --STK-----------------------------EI--VAIKILK-NHPS 37
HIPK2           --GTN-----------------------------EI--VAIKILK-NHPS 37
HIPK3           --GTN-----------------------------EI--VAIKILK-NHPS 37
HIPK4           --STG-----------------------------EM--VAIKILK-NDAY 37
PRP4            --RAN-----------------------------QE--VAVKIIR-NNEL 38
MOK             --RDG-----------------------------NY--YACKQMK-QRFE 37
1A6O            --NNN-----------------------------EK--CIIKILK-PV-- 35
1LPUA           --NNN-----------------------------EK--CIIKILK-PV-- 35
CK2A1           --TNN-----------------------------EK--VVVKILK-PV-- 35
CK2A1-RS        --TNN-----------------------------EK--VVVKILK-PV-- 35
CK2A2           --TNN-----------------------------ER--VVVKILK-PV-- 35
HSER            K-YDK-----------------------------KR--VILKDLKHNDGN 36
SLOB            N-QPK-----------------------------ER--LVLSWADL-GPD 38
CDC7            V-GPE-----------------------------EK--IALKHLI-PTSH 40
1CSN            --LNN-----------------------------QQ--VAIKF-E-PRRS 36
CK1G1           --YTN-----------------------------EY--VAIKL-E-PIKS 36
CK1G3           --YTN-----------------------------EY--VAIKL-E-PMKS 36
CK1G2           --YTN-----------------------------EY--VAIKL-E-PIKS 36
CK1A            --TNG-----------------------------EE--VAVKL-E-SQKA 36
CK1A2           --TNG-----------------------------ED--VAVKL-E-SQKV 36
1CKJA           --AAG-----------------------------EE--VAIKL-E-CVKT 36
CK1D            --AAG-----------------------------EE--VAIKL-E-CVKT 36
CK1E            --ASG-----------------------------EE--VAIKL-E-CVKT 36
TTBK1           --LTR-----------------------------EN--VALKV-E-SAQQ 36
TTBK2           --LTR-----------------------------EN--VALKV-E-SAQQ 36
TLK1            --YEQ-----------------------------RY--AAVKIHQ-LNKS 37
TLK2            --TEQ-----------------------------RY--VAVKIHQ-LNKN 37
GPRK4           --ATG-----------------------------KM--YACKKLQ-KKRI 37
GPRK6           --ATG-----------------------------KM--YACKKLE-KKRI 37
GPRK5           --ATG-----------------------------KM--YACKRLE-KKRI 37
RHOK            --ATG-----------------------------KL--YACKKLN-KKRL 37
GPRK7           --NTG-----------------------------KM--YACKKLD-KKRL 37
BARK1           --DTG-----------------------------KM--YAMKCLD-KKRI 37
BARK2           --DTG-----------------------------KM--YAMKCLD-KKRI 37
TTK             ----K-----------------------------QI--YAIKYVN-LEEA 36
RIPK1           --TQG-----------------------------LM--I-MKTVY-KGPN 36
HASPIN          ----H-----------------------------TP--VAIKIIA-IEGP 35
GCN2            ---DG-------------------------------CCYAVKRIPINPAS 38
HRI             ---DG-------------------------------QYYAIKKILIKGAT 38
KIS             ---NP-----------------------------GSPPGALKQFLPPGTT 40
PDK1            ---TS-------------------------------REYAIKILEKRHII 38
PKR             ---DG-------------------------------KTYVIKRVKYNN-- 36
PEK             ---DD-------------------------------CNYAIKRIRLPNR- 37
PRPK            ---QG-------------------------------RAAVIKHRFPKGYR 36
DOMAIN2_OBSCN   ---SG-----------------------------RA--LAAKIIPYHPKD 38
DOMAIN2_SPEG    ---TG-----------------------------RT--FVAKIVPYAAEG 38
LMR1            ---SS-----------------------------AQ--VVVKELQASASV 40
LMR2            ---SV-----------------------------AR--VIVKELKASANP 40
LMR3            ---TP-----------------------------AQ--VVVKELRASAGP 40
SGK307          -------------------------------------------------- 0
STLK5           ---TG-----------------------------EY--VTVRRINLEACS 40
STLK6           ---TG-----------------------------TL--VTIKITNLENCN 40
STLK6-RS        ---TG-----------------------------TL--VTIKITNLENCN 40
OBSCN           ---NK-----------------------------IL--CAAKFIPLRSRT 38
SPEG            ---SG-----------------------------LE--FAAKFIPSQAKP 38
TRAD            ---TR-----------------------------KD--VAVKFVSKKMKK 38
TRIO            ---TK-----------------------------RA--VATKFVNKKLMK 38
SGK223          ---AS-----------------------------VP--SSMLSSPDAP-- 52
SGK269          ---PL-----------------------------NN--YAVKICKSKAKE 39
ALK1            ----------------------------------ES--VAVKIFS----- 31
ALK2            ----------------------------------EN--VAVKIFS----- 31
IRAK4           ----------------------------------TT--VAVKKLAAMVDI 36
BMPR2           ----------------------------------RP--VAVKVFS----- 31
TGFBR2          TSEQF-----------------------------ET--VAVKIFP----- 37
ACTR2           ----------------------------------EY--VAVKIFP----- 31
ACTR2B          ----------------------------------DF--VAVKIFP----- 31
1B6CB           ----------------------------------EE--VAVKIFS----- 31
TGFBR1          ----------------------------------EE--VAVKIFS----- 31
ALK4            ----------------------------------GD--VAVKIFS----- 31
ALK7            ----------------------------------ED--VAVKIFS----- 31
BMPR1A          ----------------------------------EK--VAVKVFF----- 31
BMPR1B          ----------------------------------EK--VAVKVFF----- 31
IRAK1           ----------------------------------TV--YAVKRLKEN--- 33
IRAK2           ----G-----------------------------KP--FVFKKLRETAC- 35
IRAK3           ---LT-----------------------------Y----AVKLFKQEKK- 35
MISR2           ---QG-----------------------------KL--VAIKAFPPRSV- 35
MYT1            ---DG-----------------------------RL--YAVKRSM----S 34
SBK             ---TG-----------------------------TK--MALKFVN----K 34
SGK110          ---GG-----------------------------PA--VALKLLR----R 34
SGK069          ---KG-----------------------------TP--LALKQLP----K 34
SGK496          ---GH-----------------------------FP--CALKSVV----- 33
NIK             ---TG-----------------------------FQ--CAVKKVR----- 33
SGK424          -------------------------------------------------- 0
SURTK106        ---GD-----------------------------PS--K-PKSVILKALK 37
IKKE            ---SG-----------------------------EL--VAVKVFNTTSYL 38
TBK1            ---TG-----------------------------DL--FAIKVFNNISFL 38
MOS             ---RG-----------------------------VP--VAIKQVNK---- 32
LKB1            ---TL-----------------------------CR--RAVKILKKKKLR 38
CAMKK1          ---ED-----------------------------RH--YAMKVLSKKKLL 47
CAMKK2          ---DN-----------------------------TY--YAMKVLSKKKLI 38
PASK            ---KN-----------------------------KE--VVVKFIKKEKVL 38
PIM1            ---DN-----------------------------LP--VAIKHVEKDRIS 38
PIM3            ---DG-----------------------------LP--VAVKHVVKERVT 38
PIM2            ---DR-----------------------------LQ--VAIKVIPRNRVL 38
COT             ---TK-----------------------------KR--MACKLIPVDQFK 40
SCYL2           ---TK-----------------------------QE--VAVFVFDKKLID 41
FUSED           --------------------------GRRKYS---AQVVALKFIPK---L 35
ULK1            --------------------------GRHREKH--DLEVAVKCINK---K 36
ULK2            --------------------------GRHRQKT--DWEVAIKSINK---K 36
ULK3            --------------------------AYAKKDT--REVVAIKCVAK---K 36
ULK4            --------------------------GRRKGT---INFVAILCT------ 32
IRE1            --------------------------GMFDNR-----DVAVKRILPE--- 34
IRE2            --------------------------GQFEGR-----AVAVKRLLRE--- 34
RNASEL          --------------------------GFYEKQ-----EVAVKTFCEGSP- 31
MPSK1           -------------------------EGLHDGH-----FYALKRIL----- 33
PINK1           LPQNLEVTKSTGLLPGRGPGTSAPGEGQERAPGAPAFPLAIKMMWNISAG 72
ALK             PN-----------DP-------------------SPLQVAVKTLPEVCSE 43
LTK             PG-----------DS-------------------SPLQVAIKTLPELCSP 43
ROS             LG----------VGS-------------------GEIKVAVKTLKKGSTD 44
IGF1R           VK-----------DE-------------------PETRVAIKTVNEAASM 43
1IR3A           IK-----------GE-------------------AETRVAVKTVNESASL 43
INSR            IK-----------GE-------------------AETRVAVKTVNESASL 43
IRR             EA-----------GE-------------------ESTPVALKTVNELASP 43
1M14A           EG-----------EK-------------------VKIPVAIKELREATSP 42
EGFR            EG-----------EK-------------------VKIPVAIKELREATSP 42
HER2/ERBB2      DG-----------EN-------------------VKIPVAIKVLRENTSP 42
HER4/ERBB4      EG-----------ET-------------------VKIPVAIKILNETTGP 42
HER3/ERBB3      EG-----------ES-------------------IKIPVCIKVIEDKSGR 42
ITK             -----------------------------------KDKVAIKTIREGAM- 36
TEC             --------------R-------------------AQYKVAIKAIREGAM- 36
TXK             --------------R-------------------SHIQVAIKAINEGSM- 36
BMX             ----------------------------------GQYDVAVKMIKEGSM- 36
1K2PA           ----------------------------------GQYDVAIKMIKEGSM- 36
BTK             ----------------------------------GQYDVAIKMIKEGSM- 36
CCK4            EE-----------GV-------------------AETLVLVKSLQS-KDE 42
ROR1            G------------MD-------------------HAQLVAIKTLKDYNNP 42
ROR2            AP-----------GE-------------------QTQAVAIKTLKDKAEG 43
MUSK            LP-----------YE-------------------PFTMVAVKMLKEEASA 43
TRKA            LP-----------EQ-------------------DKMLVAVKALKEA-SE 42
TRKB            CP-----------EQ-------------------DKILVAVKTLKDA-SD 42
TRKC            SP-----------TK-------------------DKMLVAVKALKDPTLA 43
DDR1            QDLVSLDFPLNVRKG-------------------HPLLVAVKILRPDATK 54
DDR2            EKFKDKDFALDVSAN-------------------QPVLVAVKMLRADANK 54
RYK             KD-----------PN-------------------KEKQAFVKTVKDQASE 43
JAK1            EDNTG-----------------------------EQ--VAVKSLK--PE- 38
JAK2            QDNTG-----------------------------EV--VAVKKLQ--H-- 38
JAK3            AHNTG-----------------------------AL--VAVKQLQ--H-- 38
ACK             S-GKT-----------------------------VS--VAVKCLK--PDV 39
TYK2            NDGTG-----------------------------EM--VAVKALK--ADC 40
TNK1            PSGKS-----------------------------VP--VAVKSLRVGPEG 41
EPHA1           -SQDCKT-------------------------------VAIKTLKDTSPG 41
EPHA10          -GRQELL-------------------------------VAVHMLRDSASD 41
FAK             -ENPALA-------------------------------VAIKTCKNCTSD 41
EPHB6           -GRREQT-------------------------------VAIQALWAGGAE 41
EPHA2           SGKKEVP-------------------------------VAIKTLKAGYTE 42
EPHA8           -GQRDVP-------------------------------VAIKALKAGYTE 41
EPHA6           -GKREIP-------------------------------VAIKTLKGGHMD 41
EPHB1           -GKREIY-------------------------------VAIKTLKAGYSE 41
EPHB2           -GKREIF-------------------------------VAIKTLKSGYTE 41
EPHB3           -GRREVF-------------------------------VAIKTLKVGYTE 41
EPHB4           -GKKESC-------------------------------VAIKTLKGGYTE 41
EPHA7           -GKRDVA-------------------------------VAIKTLKVGYTE 41
EPHA4           -GKREIC-------------------------------VAIKTLKAGYTD 41
EPHA3           -SKKEIS-------------------------------VAIKTLKVGYTE 41
EPHA5           -GKRELP-------------------------------VAIKTLKVGYTE 41
PYK2            -KGEKIN-------------------------------VAVKTCKKDCTL 41
CSK             ----N------------------------------K--VAVKCIKN---- 32
CTK             ----Q------------------------------K--VAVKNIKC---- 32
1IEPA           ---YS-----------------------------LT--VAVKTLKED--- 35
ABL             ---YS-----------------------------LT--VAVKTLKED--- 35
ARG             ---YS-----------------------------LT--VAVKTLKED--- 35
BRK             ----R-----------------------------VQ--VAIKVISRD--- 34
SRM             ----S-----------------------------LP--VAIKVIKSA--- 34
FRK             ----T-----------------------------TP--VAVKTLKPG--- 34
FGR             ----S-----------------------------TK--VAVKTLKPG--- 34
FYN             ----N-----------------------------TK--VAIKTLKPG--- 34
SRC             ----T-----------------------------TR--VAIKTLKPG--- 34
YES             ----T-----------------------------TK--VAIKTLKPG--- 34
HCK             ----H-----------------------------TK--VAVKTMKPG--- 34
LYN             ----S-----------------------------TK--VAVKTLKPG--- 34
3LCK            ----H-----------------------------TK--VAVKSLKQG--- 34
LCK             ----H-----------------------------TK--VAVKSLKQG--- 34
BLK             ----N-----------------------------MK--VAIKTLKEG--- 34
FER             ----K-----------------------------TS--VAVKTCKEDLPQ 37
FES             ---DN-----------------------------TL--VAVKSCRETLPP 38
SYK             --KVV-----------------------------KT--VAVKILKNEAND 40
ZAP70           --KKQ-----------------------------ID--VAIKVLK-QGTE 39
FGFR1           DKDKPNRV--------------------------TK--VAVKMLK-SDAT 44
FGFR2           DKDKPKEA--------------------------VT--VAVKMLK-DDAT 44
FGFR3           DKDRAAKP--------------------------VT--VAVKMLK-DDAT 44
FGFR4           DPARPDQA--------------------------ST--VAVKMLK-DNAS 44
RET             KGRA--GY--------------------------TT--VAVKMLK-ENAS 42
TIE1            KKDG--LK--------------------------MN--AAIKMLK-EYAS 39
1FVRA           KKDG--LR--------------------------MD--AAIKRMK-EYAS 39
TIE2            KKDG--LR--------------------------MD--AAIKRMK-EYAS 39
FLT1            KKSP--TC--------------------------RT--VAVKMLK-EGAT 42
KDR             DKTA--TC--------------------------RT--VAVKMLK-EGAT 42
KDR_AVE         DKTA--TC--------------------------RT--VAVKMLK-EGAT 42
FLT4            HKGS--SC--------------------------DT--VAVKMLK-EGAT 42
FMS             GKED--AV--------------------------LK--VAVKMLK-STAH 42
FLT3            SKTG--VS--------------------------IQ--VAVKMLK-EKAD 42
KIT             IKSD--AA--------------------------MT--VAVKMLK-PSAH 42
PDGFRA          SRSQ--PV--------------------------MK--VAVKMLK-PTAR 42
PDGFRB          SHSQ--AT--------------------------MK--VAVKMLK-STAR 42
MER             QEDG--TS--------------------------LK--VAVKTMKLDNSS 41
AXL             NQDD--SI--------------------------LK--VAVKTMKIAICT 40
TYRO3           QEDG--SF--------------------------VK--VAVKMLKADIIA 41
MET             DNDG--KK--------------------------IH--CAVKSLN-RITD 40
RON             DQAQ--NR--------------------------IQ--CAIKSLS-RITE 40
HH498           CRN-------------------------------KI--VAIKRYRANTYC 36
LZK             FRA-------------------------------EE--VAIKKVREQNET 36
DLK             FHG-------------------------------EE--VAVKKVRDLKET 36
MLK1            WIG-------------------------------DE--VAVKAARHDPDE 36
MLK3            WRG-------------------------------EL--VAVKAARQDPDE 36
MLK2            WRG-------------------------------EE--VAVKAARLDPEK 36
MLK4            WQG-------------------------------QE--VAVKAARQDPEQ 36
ZAK             WISQD-----------------------------KE--VAVKKLL----- 33
TAK1            WRA-------------------------------KD--VAIKQIES---- 32
KSR1            WHG-------------------------------E---VAIRLLEMDGHN 35
KSR2            WHG-------------------------------E---VAIRLIDIERDN 35
ARAF            WHG-------------------------------D---VAVKVLKVSQPT 35
RAF1            WHG-------------------------------D---VAVKILKVVDPT 35
BRAF            WHG-------------------------------D---VAVKMLNVTAPT 35
LRRK2           YEG-------------------------------EE--VAVKIFNKH--- 33
ANKRD3          HVHWK-----------------------------TW--LAIKCSPSLHVD 38
SGK288          HRRWR-----------------------------TE--YAIKCAPCLPPD 35
RIPK2           HADWR-----------------------------VQ--VAVKHLHIHTP- 37
RIPK3           HRKWG-----------------------------YD--VAVKIVNS---- 34
MLKL            YHR-------------------------------AP--VAIKVFKKLQAG 31
ANPA            YKG-------------------------------NL--VAVKRVNRKRIE 41
ANPB            FKG-------------------------------NV--VAIKHVNKKRIE 41
CYGD            YEG-------------------------------DR--VWLKKFPGDQHI 39
CYGF            YEG-------------------------------DW--VWLKKFSLGDFG 51
TBCK            --------------------------------------NSIKIL------ 22
ERK1            V--RK-----------------------------TR--VAIKKIS-PFEH 37
3ERK            L--NK-----------------------------VR--VAIKKIS-PFEH 37
ERK2            V--NK-----------------------------VR--VAIKKIS-PFEH 37
ERK5            L--TG-----------------------------QQ--VAIKKIPNAFDV 38
1JNK            V--LD-----------------------------RN--VAIKKLSRPFQN 38
1PMNA           V--LD-----------------------------RN--VAIKKLSRPFQN 38
JNK3            V--LD-----------------------------RN--VAIKKLSRPFQN 38
JNK1            I--LE-----------------------------RN--VAIKKLSRPFQN 38
JNK2            V--LG-----------------------------IN--VAVKKLSRPFQN 38
1P38            K--TG-----------------------------HR--VAVKKLSRPFQS 38
P38A            K--TG-----------------------------LR--VAVKKLSRPFQS 38
P38B            R--LR-----------------------------QK--VAVKKLSRPFQS 38
P38D            R--SG-----------------------------EK--VAIKKLSRPFQS 38
P38G            R--TG-----------------------------AK--VAIKKLYRPFQS 38
NLK             R--DG-----------------------------KR--VALKKMPNVFQN 38
ERK7            R--TG-----------------------------EV--VAIKKIFDAFRD 38
ERK3            D--CD-----------------------------KR--VAIKKIVLTDPQ 38
ERK4            R--AC-----------------------------RK--VAVKKIALSDAR 38
ICK             E--SG-----------------------------EL--IAIKKMKRKFYS 38
MAK             E--SG-----------------------------EL--VAIKRMKRKFYS 38
PCTAIRE1        L--TD-----------------------------NL--VALKEIRLEHE- 37
PCTAIRE2        L--TE-----------------------------NL--VALKEIRLEHE- 37
PCTAIRE3        L--TE-----------------------------NL--VALKEIRLEHE- 37
PFTAIRE1        V--NG-----------------------------KL--VALKVIRLQEE- 37
PFTAIRE2        I--NG-----------------------------QL--VALKVISMNAE- 37
CDC2            T--TG-----------------------------QV--VAMKKIRLESEE 38
1HCL            L--TG-----------------------------EV--VALKKIR----T 34
CDK2            L--TG-----------------------------EV--VALKKIRLDTET 38
CDK3            E--TG-----------------------------QL--VALKKIRLDLEM 38
CDK5            E--TH-----------------------------EI--VALKRVRLDDDD 38
CDK7            N--TN-----------------------------QI--VAIKKIKLGHRS 38
CDK4            H--SG-----------------------------HF--VALKSVRVPNGG 38
1BLXA           K-NGG-----------------------------RF--VALKRVRVQTGE 39
CDK6            K-NGG-----------------------------RF--VALKRVRVQTGE 39
PITSLRE         K--TD-----------------------------EI--VALKRLKMEKEK 38
CDK10           Q--TD-----------------------------EI--VALKKVRMDKEK 38
CDK9            K--TG-----------------------------QK--VALKKVLMENEK 38
CHED            D--TG-----------------------------EM--VALKKVRLDNEK 38
CRK7            D--TG-----------------------------EL--VALKKVRLDNEK 38
CCRK            E--TG-----------------------------EI--VALKKVALRRLE 38
CDK11           K--DE-----------------------------KE--YALKQI----EG 37
CDK8            K--DD-----------------------------KD--YALKQI----EG 37
IKKA            ---LD-----------------------------LK--IAIKSCRLELST 38
IKKB            ---TG-----------------------------EQ--IAIKQCRQELSP 38
1PHK            ---TC-----------------------------KE--YAVKIIDVTGGG 38
PHKG1           ---TS-----------------------------QE--YAVKVIDVTGGG 38
PHKG2           ---TG-----------------------------HE--FAVKIMEVTAER 38
CAMK2A          ---AG-----------------------------QE--YAAKIINTKK-- 36
CAMK2B          ---TG-----------------------------HE--YAAKIINTKK-- 36
CAMK2G          ---ST-----------------------------QE--YAAKIINTKK-- 36
CAMK2D          ---TG-----------------------------QG--YAAKIINTKK-- 36
CASK            ---TG-----------------------------QQ--FAVKIVDVAKFT 38
1IA8A           ---TE-----------------------------EA--VAVKIVDMKR-- 36
CHK1            ---TE-----------------------------EA--VAVKIVDMKRAV 38
CLK1            ---GG-----------------------------RH--VAVKIVK----- 34
CLK4            ---DG-----------------------------MH--VAVKIVK----- 33
CLK2            ---GG-----------------------------AR--VALKIIK----- 34
CLK3            ---GK-----------------------------SQ--VALKIIR----- 34
MAP2K5          ---SG-----------------------------KI--LAVKVILLDITL 38
MAP2K3          ---SG-----------------------------TI--MAVKRIRATVNS 38
MAP2K6          ---SG-----------------------------QI--MAVKRIRATVNS 38
MAP2K4          ---SG-----------------------------QI--MAVKRIRSTVDE 38
MAP2K7          ---TG-----------------------------HV--IAVKQMRRSGNK 38
MAP2K1          ---SG-----------------------------LV--MARKLIHLEIKP 38
MAP2K2          ---SG-----------------------------LI--MARKLIHLEIKP 38
CDKL5           ---TH-----------------------------EI--VAIKKFKDSEEN 38
CDKL1           ---TG-----------------------------QI--VAIKKFLESEDD 38
CDKL4           ---SG-----------------------------QV--VAVKKFVESEDD 38
CDKL2           ---TG-----------------------------RI--VAIKKFLESDDD 38
CDKL3           ---TG-----------------------------QI--VAIKIFYERPEQ 38
1I09B           ---SG-----------------------------EL--VAIKKVLQD--- 35
GSK3B           ---SG-----------------------------EL--VAIKKVLQD--- 35
1J1BA           ---SG-----------------------------EL--VAIKKVLQD--- 35
GSK3A           ---TR-----------------------------EL--VAIKKVLQD--- 35
LATS1           ---TK-----------------------------AL--YATKTLRKKDVL 38
LATS2           ---TH-----------------------------AL--YAMKTLRKKDVL 38
NDR1            ---TG-----------------------------HV--YAMKILRKADML 38
NDR2            ---TG-----------------------------HI--YAMKILRKSDML 38
MAST1           ---TR-----------------------------QR--FAMKKINKQNLI 38
MAST4           ---SR-----------------------------QR--FAMKKINKQNLI 38
MAST2           ---TR-----------------------------QR--FAMKKINKQNLI 38
MAST3           ---TR-----------------------------QR--FAIKKINKQNLI 38
MRCKA           ---AD-----------------------------KV--FAMKILNKWEML 38
MRCKB           ---TE-----------------------------RI--YAMKILNKWEML 38
DMPK2           ---TG-----------------------------QI--FAMKMLHKWEML 38
DMPK1           ---TG-----------------------------QV--YAMKIMNKWDML 38
ROCK1           ---TR-----------------------------KV--YAMKLLSKFEMI 38
ROCK2           ---SQ-----------------------------KV--YAMKLLSKFEMI 38
CRIK            ---TG-----------------------------DI--YAMKVMKKKALL 38
MASTL           ---GG-----------------------------KL--YAVKVVKKADMI 36
1O6LA           KAT-G-----------------------------RY--YAMKILRKEVII 38
AKT2            KAT-G-----------------------------RY--YAMKILRKEVII 38
AKT1            KAT-G-----------------------------RY--YAMKILKKEVIV 38
AKT3            KAS-G-----------------------------KY--YAMKILKKEVII 38
MSK1            HDT-G-----------------------------KL--YAMKVLKKATIV 41
MSK2            HDA-G-----------------------------KL--YAMKVLRKAALV 41
P70S6K          ANT-G-----------------------------KI--FAMKVLKKAMIV 41
P70S6KB         TNL-G-----------------------------KI--YAMKVLRKAKIV 41
RSK1            SDA-G-----------------------------QL--YAMKVLKKATLK 41
RSK3            PDS-G-----------------------------HL--YAMKVLKKATLK 41
RSK2            SDA-R-----------------------------QL--YAMKVLKKATLK 41
RSK4            PDA-G-----------------------------QL--YAMKVLKKASLK 41
1FOTA           RHN-G-----------------------------RY--YAMKVLKKEIVV 38
1CDKA           KET-G-----------------------------NH--FAMKILDKQKVV 38
PKACA           KET-G-----------------------------NH--YAMKILDKQKVV 38
PKACB           KAT-E-----------------------------QY--YAMKILDKQKVV 38
PKACG           QET-G-----------------------------GH--YAMKILNKQKVV 38
PRKX            KTA-K-----------------------------HF--FALKVMSIPDVI 38
PRKY            KTA-K-----------------------------HF--FALKVMSIPDVI 38
PKCA            KGT-E-----------------------------EL--YAIKILKKDVVI 38
PKCB            KGT-D-----------------------------EL--YAVKILKKDVVI 38
PKCG            RGS-D-----------------------------EL--YAIKILKKDVIV 38
PKCE            KGK-D-----------------------------EV--YAVKVLKKDVIL 38
PKCH            KET-G-----------------------------DL--YAVKVLKKDVIL 38
PKCD            KGR-G-----------------------------EY--FAIKALKKDVVL 38
PKCT            KKT-N-----------------------------QF--FAIKALKKDVVL 38
PKCI            KKT-D-----------------------------RI--YAMKVVKKELVN 38
PKCZ            KKN-D-----------------------------QI--YAMKVVKKELVH 38
PKN1            RPS-G-----------------------------EL--FAIKALKKGDIV 38
PKN2            KNT-N-----------------------------EM--FAIKALKKGDIV 38
PKN3            KGT-G-----------------------------KY--YAIKALKKQEVL 38
SGK             KAE-E-----------------------------VF--YAVKVLQKKAIL 38
SGK2            KSD-G-----------------------------AF--YAVKVLQKKSIL 38
SGK3            KLD-G-----------------------------KF--YAVKVLQKKIVL 38
PKG1            KSEES-----------------------------KT--FAMKILKKRHIV 39
PKG2            KNE-N-----------------------------VA--FAMKCIRKKHIV 38
AURB            ---SH-----------------------------FI--VALKVLFKSQIE 38
AURC            ---SH-----------------------------FI--VALKVLFKSQIE 38
AURA            ---SK-----------------------------FI--LALKVLFKAQLE 38
AURORA2_AVE     ---SK-----------------------------FI--LALKVLFKAQLE 38
PLK1            ---TK-----------------------------EV--FAGKIVPKSLLL 38
PLK2            ---NN-----------------------------KV--YAAKIIPHSRVA 38
PLK3            ---TG-----------------------------SA--YAVKVIPQSRVA 38
PLK4            ---TG-----------------------------LE--VAIKMIDKKAMY 38
NEK11           ---AK-----------------------------RG--EELKVLKEISVG 38
YANK1           ---TK-----------------------------KM--YAMKYMNKQKCV 38
YANK2           ---TK-----------------------------KM--YAMKYMNKQKCI 38
YANK3           ---TE-----------------------------KM--YAMKYMNKQQCI 38
SGK494          ---QK-----------------------------AV--FAVKVVPKVKVL 38
DOMAIN2_MSK1    ---SN-----------------------------QA--FAVKIISKRME- 37
DOMAIN2_MSK2    ---SG-----------------------------QE--FAVKILSRRLE- 31
DOMAIN2_RSK1    ---TD-----------------------------TE--YAVKIIDKSKR- 37
DOMAIN2_RSK2    ---TN-----------------------------ME--FAVKIIDKSKR- 37
DOMAIN2_RSK3    ---TN-----------------------------ME--YAVKVIDKSKR- 37
DOMAIN2_RSK4    ---TN-----------------------------ME--FAVKIIDKSKR- 37
DRAK1           ---SG-----------------------------KE--FAAKFMRKRRKG 38
DRAK2           ---TG-----------------------------QE--YAAKFLKKRRRG 38
1JKSA           ---TG-----------------------------LQ--YAAKFIKKRRTK 38
DAPK1           ---TG-----------------------------LQ--YAAKFIKKRRTK 38
DAPK3           ---TG-----------------------------KE--YAAKFIKKRRLS 38
DAPK2           ---TG-----------------------------LE--YAAKFIKKRQSR 38
SGK085          ---TG-----------------------------LK--LAAKIIKTRGMK 38
CAMLCK          ---TG-----------------------------LP--LAAKIIKVKSAK 38
SKMLCK          ---TG-----------------------------LK--LAAKVIKKQTPK 38
SMMLCK          ---TR-----------------------------KV--WAGKFFKAYSAK 38
1KOBA           ---TG-----------------------------RV--FVAKFINTPYPL 38
1TKIA           ---SK-----------------------------KT--YMAKFVKVKGT- 37
TTN             ---SK-----------------------------KT--YMAKFVKVKGT- 37
PKD1            ---TG-----------------------------RD--VAIKIIDKLRFP 38
PKD3            ---TG-----------------------------RD--VAIKVIDKMRFP 38
PKD2            ---TG-----------------------------RD--VAVKVIDKLRFP 38
PSKH1           ---TR-----------------------------QP--YAIKMIETKYRE 38
PSKH2           ---TK-----------------------------KP--FAIKVMETRERE 38
CAMK1A          ---TQ-----------------------------KL--VAIKCIAKEALE 38
CAMK1D          ---TG-----------------------------KL--FAVKCIPKKALK 38
CAMK1B          ---SA-----------------------------HL--VALKCIPKKALR 38
CAMK1G          ---TG-----------------------------KL--FALKCIKKSPAF 38
CAMK4           ---TQ-----------------------------KP--YALKVLKKTV-- 36
DCAMKL1         ---TA-----------------------------RE--YALKIIKKSKCR 38
DCAMKL2         ---TG-----------------------------KE--FALKIIDKAKCC 38
DCAMKL3         ---TR-----------------------------QA--YAMKIIDKSRLK 38
CHK2            ---TC-----------------------------KK--VAIKIISKRKFA 38
MAPKAPK2        ---TQ-----------------------------EK--FALKMLQDCPK- 37
MAPKAPK3        ---TG-----------------------------QK--CALKLLYDSPK- 37
MAPKAPK5        ---TQ-----------------------------ER--FALKILLDRPK- 37
MNK1            ---NG-----------------------------KE--YAVKIIEKQAGH 39
MNK2            ---TS-----------------------------QE--YAVKIIEKQPGH 38
VACAMKL         ---TG-----------------------------KL--HTCKKFQKRDGR 38
GCK             ---TS-----------------------------EL--AAVKIVKLDPG- 37
KHS1            ---TG-----------------------------EL--AAVKIIKLEPG- 37
KHS2            ---TG-----------------------------EL--AAIKVIKLEPG- 37
HPK1            ---SG-----------------------------DL--VALKMVKMEPD- 37
MST1            ---TG-----------------------------QI--VAIKQVPVESD- 37
MST2            ---SG-----------------------------QV--VAIKQVPVESD- 37
MST3            ---TQ-----------------------------KV--VAIKIIDLEEA- 37
YSK1            ---TK-----------------------------EV--VAIKIIDLEEA- 37
MST4            ---TQ-----------------------------QV--VAIKIIDLEEA- 37
LOK             ---TG-----------------------------AL--AAAKVIETKSE- 37
SLK             ---TS-----------------------------VL--AAAKVIDTKSE- 37
MAP3K4          ---TG-----------------------------EL--MAMKEIRFQPN- 37
MAP3K2          ---TG-----------------------------RE--LAVKQVQFDPD- 37
MAP3K3          ---TG-----------------------------RE--LASKQVQFDPD- 37
MAP3K8          ----G-----------------------------QL--IAVKQVALDTS- 36
MAP3K5          ---NQ-----------------------------VR--IAIKEIPERDS- 42
MAP3K7          ---NQ-----------------------------VR--IAIKEIPERDS- 35
MAP3K6          ---TR-----------------------------VR--IAIKEIPERDS- 32
PAK1            ---TG-----------------------------QE--VAIKQMNLQQQ- 37
PAK3            ---TG-----------------------------QE--VAIKQMNLQQQ- 37
PAK2            ---LG-----------------------------QE--VAIKQINLQKQ- 37
PAK4            ---SG-----------------------------KL--VAVKKMDLRKQ- 37
PAK5            ---TG-----------------------------KQ--VAVKKMDLRKQ- 37
PAK6            ---SG-----------------------------RQ--VAVKMMDLRKQ- 37
OSR1            ---KK-----------------------------EK--VAIKRINLEKC- 37
STLK3           ---RQ-----------------------------ER--VAIKRINLEKC- 37
TAO1            ---TN-----------------------------EV--VAIKKMSYSG-- 36
TAO3            ---TN-----------------------------EV--VAIKKMSYSG-- 36
TAO2            ---NS-----------------------------EV--VAIKKMSYSG-- 36
MYO3A           ---NG-----------------------------QK--AAVKILDPIHD- 37
MYO3B           ---DG-----------------------------SL--AAVKILDPVSD- 37
ZC1/HGK         ---TG-----------------------------QL--AAIKVMDVTED- 37
ZC3/MINK        ---TG-----------------------------QL--AAIKVMDVTED- 37
ZC2/TNIK        ---TG-----------------------------QL--AAIKVMDVTGD- 37
ZC4/NRK         ---TG-----------------------------AF--TAVKVMNARKTP 38
MAP3K1          ---TG-----------------------------TL--MAVKQVTYVRN- 37
GAK             ---SG-----------------------------RE--YALKRLLSNEE- 37
SGK495          -------------------------------------------------- 0
TRB1            ---TG-----------------------------RE--LRCKVFPIKHYQ 30
TRB2            ---SG-----------------------------EE--LVCKVFDISCYQ 35
TRB3            ---TG-----------------------------TE--YTCKVYPVQEA- 32
SSTK            ---YK-----------------------------GT--VAIKVVDRRRAP 38
TSSK3           ---HQ-----------------------------RK--VAIKVIDKMGGP 38
TSSK1           ---LK-----------------------------FN--VAIKIIDRKKAP 38
TSSK2           ---LK-----------------------------FN--VAVKIIDRRKTP 38
TSSK4           ---QK-----------------------------VM--VAVKIISKKKAS 38
HUNK            ---TG-----------------------------EK--VAIKVIDKKRAK 39
SNRK            ---TG-----------------------------EK--VAVKVIDKTKLD 38
NIM1            ---TK-----------------------------EK--VAIKILDKTKLD 38
MELK            ---TG-----------------------------EM--VAIKIMDKNTLG 38
BRSK1           ---TG-----------------------------QK--VAIKIVNREKLS 38
BRSK2           ---TC-----------------------------QK--VAIKIVNREKLS 38
MARK1           ---TG-----------------------------RE--VAVKIIDKTQLN 38
MARK2           ---TG-----------------------------KE--VAVKIIDKTQLN 38
MARK3           ---TG-----------------------------RE--VAIKIIDKTQLN 38
MARK4           ---TG-----------------------------RE--VAIKIIDKTQLN 38
QIK             ---TK-----------------------------TE--VAIKIIDKSQLD 38
SIK             ---TK-----------------------------TQ--VAIKIIDKTRLD 38
QSK             ---TK-----------------------------AK--VAIKIIDKTQLD 38
AMPKA1          ---TG-----------------------------HK--VAVKILNRQKIR 38
AMPKA2          ---TG-----------------------------HK--VAVKILNRQKIR 38
NUAK1           ---SG-----------------------------RV--VAIKSIRKDKIK 38
NUAK2           ---SG-----------------------------RL--VAIKSIRKDKIK 37
BIKE            ---GG-----------------------------IR--CALKRMYVNNMP 37
AAK1            ---NG-----------------------------MK--CALKRMFVNNE- 36
LIMK1           ---TG-----------------------------EV--MVMKELI--RFD 36
LIMK2           ---TG-----------------------------KV--MVMKELI--RCD 36
TESK1           ---SG-----------------------------QV--MVLKMNKL---- 34
TESK2           ---SG-----------------------------QV--MALKMNTL---- 30
WNK1            ---TT-----------------------------VE--VAWCELQDRKLT 38
WNK3            ---TW-----------------------------VE--VAWCELQDRKLT 38
WNK2            ---TW-----------------------------VE--VAWCELQDRKLT 38
WNK4            ---TT-----------------------------VE--VAWCELQTRKLS 38
NEK10           ---GQ-----------------------------NL--LAMKEVNLHNPA 38
NEK6            ---DR-----------------------------KT--VALKKVQIFEMM 38
NEK7            ---DG-----------------------------VP--VALKKVQIFDLM 38
NEK2            ---DG-----------------------------KI--LVWKELDYGSMT 38
NEK1            ---DG-----------------------------RQ--YVIKEINISRMS 38
NEK5            ---DS-----------------------------KH--CVIKEINFEKMP 38
NEK3            ---SN-----------------------------QM--FAMKEIRLPK-S 37
NEK4            ---DG-----------------------------KQ--YVIKKLNLRNAS 38
NEK8            ---DQ-----------------------------KL--VIIKQIPVEQMT 38
NEK9            ---DD-----------------------------SL--VVWKEVDLTRLS 38
NRBP1           ---EG-----------------------------VE--VVWNEVQFSERK 41
NRBP2           ---EG-----------------------------VE--VVWNELHFGDRK 41
CLIK1           ---SG-----------------------------AR--VAVKKIRCDAPE 38
CLIK1L          ---TS-----------------------------AR--VAVKKIRCHAPE 38
STK33           ---TE-----------------------------TK--WAIKKVNKEKAG 38
DOMAIN2_GCN2    KLV-----------------------------------YNALETATGGFV 29
SCYL1           -------------------------------------------------- 19
SCYL3           ----------------------------------------YKREN----- 22
DOMAIN2_JAK1    ----------------------------------------GTLMDYKDDE 27
DOMAIN2_TYK2    ----------------------------------------GRLRVEGSGD 27
DOMAIN2_JAK2    ----------------------------------------GVRREVGDYG 27
DOMAIN2_JAK3    ----------------------------------------GCRHEVVDGE 27
ILK             ----------------------------------------GRWQGNDIV- 26
LRRK1           ---------------------------------------RARYQGQPVA- 27
PBK             ----------------------------------------MKRSPRGLSH 27
WEE1            ----------------------------------------CVKRLDGCI- 26
WEE1B           ----------------------------------------CIKRLDGCV- 26
SGK071          -------------------------------------------------- 17
PIK3R4          ----------------------------------------AKHREGLVV- 26
MSSK1           -------------------------------------------------- 17
SRPK1           -------------------------------------------------- 17
SRPK2           -------------------------------------------------- 17
RSKL1           NEY-----------------------------------I----------- 11
RSKL2           TFV-----------------------------------VKSLPRCHMVSR 35
SGK396          ---------------------------------------RSEVNGQIIL- 24
VRK1            ----------------------------------------ADMNSSESVG 27
VRK2            ----------------------------------------AFPTNKPE-- 25
VRK3            -------------------------------------------------- 0
BUB1            ----------------------------------------ATQGDLND-- 25
BUBR1           ----------------------------------------REYLICEDYK 27
SGK196          ----------------------------------------SEWKEHKVA- 26
SGK493          ----------------------------------------VRLPGGAAVA 24
                                                                  

DYRK1A          FL-----NQ----------------------------------------- 41
DYRK1B          FL-----NQ----------------------------------------- 41
DYRK2           FH-----RQ----------------------------------------- 41
DYRK3           FH-----RQ----------------------------------------- 41
DYRK4           FH-----QQ----------------------------------------- 41
HIPK1           YA-----RQ----------------------------------------- 41
HIPK2           YA-----RQ----------------------------------------- 41
HIPK3           YA-----RQ----------------------------------------- 41
HIPK4           RN-----RI----------------------------------------- 41
PRP4            MQ-----KT----------------------------------------- 42
MOK             SI-----EQ----------------------------------------- 41
1A6O            -----KKKK----------------------------------------- 39
1LPUA           -----KKKK----------------------------------------- 39
CK2A1           -----KKKK----------------------------------------- 39
CK2A1-RS        -----KKKK----------------------------------------- 39
CK2A2           -----KKKK----------------------------------------- 39
HSER            FT-----EK----------------------------------------- 40
SLOB            KY------L----------------------------------------- 41
CDC7            PI------------------------------------------------ 42
1CSN            -----DAPQ----------------------------------------- 40
CK1G1           -----RAPQ----------------------------------------- 40
CK1G3           -----RAPQ----------------------------------------- 40
CK1G2           -----RAPQ----------------------------------------- 40
CK1A            -----RHPQ----------------------------------------- 40
CK1A2           -----KHPQ----------------------------------------- 40
1CKJA           -----KHPQ----------------------------------------- 40
CK1D            -----KHPQ----------------------------------------- 40
CK1E            -----KHPQ----------------------------------------- 40
TTBK1           -----PKQV----------------------------------------- 40
TTBK2           -----PKQV----------------------------------------- 40
TLK1            WR-DEKKEN----------------------------------------- 45
TLK2            WR-DEKKEN----------------------------------------- 45
GPRK4           -----KKRK----------------------------------------- 41
GPRK6           -----KKRK----------------------------------------- 41
GPRK5           -----KKRK----------------------------------------- 41
RHOK            -----KKRK----------------------------------------- 41
GPRK7           -----KKKG----------------------------------------- 41
BARK1           -----KMKQ----------------------------------------- 41
BARK2           -----KMKQ----------------------------------------- 41
TTK             DN-----QT----------------------------------------- 40
RIPK1           CI-----EH----------------------------------------- 40
HASPIN          DLVNGSHQK----------------------------------------- 44
GCN2            RQF-R--------------------------------------------- 42
HRI             KTVCM--------------------------------------------- 43
KIS             GAAAS--------------------------------------------- 45
PDK1            KENKV--------------------------------------------- 43
PKR             ----E--------------------------------------------- 37
PEK             ELARE--------------------------------------------- 42
PRPK            HPALE--------------------------------------------- 41
DOMAIN2_OBSCN   --K----------------------------------------------- 39
DOMAIN2_SPEG    --K----------------------------------------------- 39
LMR1            QEQ----------------------------------------------- 43
LMR2            KEQ----------------------------------------------- 43
LMR3            LEQ----------------------------------------------- 43
SGK307          -------------------------------------------------- 0
STLK5           NEM----------------------------------------------- 43
STLK6           EER----------------------------------------------- 43
STLK6-RS        EER----------------------------------------------- 43
OBSCN           --R----------------------------------------------- 39
SPEG            --K----------------------------------------------- 39
TRAD            --K----------------------------------------------- 39
TRIO            --R----------------------------------------------- 39
SGK223          KDP----------------------------------------------- 55
SGK269          --S----------------------------------------------- 40
ALK1            SRDEQSWFR----------------------------------------- 40
ALK2            SRDEKSWFR----------------------------------------- 40
IRAK4           TTEEL--------------------------------------------- 41
BMPR2           FANRQNFIN----------------------------------------- 40
TGFBR2          YEEYASWKT----------------------------------------- 46
ACTR2           IQDKQSWQN----------------------------------------- 40
ACTR2B          LQDKQSWQS----------------------------------------- 40
1B6CB           SREERSWFR----------------------------------------- 40
TGFBR1          SREERSWFR----------------------------------------- 40
ALK4            SREERSWFR----------------------------------------- 40
ALK7            SRDERSWFR----------------------------------------- 40
BMPR1A          TTEEASWFR----------------------------------------- 40
BMPR1B          TTEEASWFR----------------------------------------- 40
IRAK1           --ADLEWTA----------------------------------------- 40
IRAK2           -SSPGSIE------------------------------------------ 42
IRAK3           -MQCKKHW------------------------------------------ 42
MISR2           -AQF---------------------------------------------- 38
MYT1            PFRGPKDR------------------------------------------ 42
SBK             S---KTKL------------------------------------------ 39
SGK110          D---LVLR------------------------------------------ 39
SGK069          P---RTSL------------------------------------------ 39
SGK496          -PPDEKHW------------------------------------------ 40
NIK             -------L------------------------------------------ 34
SGK424          -------------------------------------------------- 0
SURTK106        EPAGLHEV------------------------------------------ 45
IKKE            R------------------------------------------------- 39
TBK1            R------------------------------------------------- 39
MOS             -------------------------------------------------- 32
LKB1            R--------IPNGE------------------------------------ 44
CAMKK1          KQYGFPRRPPPRGSQAAQGG------------------------------ 67
CAMKK2          RQAAFPRRPPPRGTRPAPGG------------------------------ 58
PASK            ED------------------------------------------------ 40
PIM1            D------------------------------------------------- 39
PIM3            E------------------------------------------------- 39
PIM2            G------------------------------------------------- 39
COT             -------------------------------------------------- 40
SCYL2           KYQKF--------------------------------------------- 46
FUSED           -------------------------------------------------- 35
ULK1            -------------------------------------------------- 36
ULK2            -------------------------------------------------- 36
ULK3            -------------------------------------------------- 36
ULK4            -------------------------------------------------- 32
IRE1            -------------------------------------------------- 34
IRE2            -------------------------------------------------- 34
RNASEL          -------------------------------------------------- 31
MPSK1           -------------------------------------------------- 33
PINK1           SSSEAILNTMSQELVPASRV------------------------------ 92
ALK             -------------------------------------------------- 43
LTK             -------------------------------------------------- 43
ROS             -------------------------------------------------- 44
IGF1R           -------------------------------------------------- 43
1IR3A           -------------------------------------------------- 43
INSR            -------------------------------------------------- 43
IRR             -------------------------------------------------- 43
1M14A           -------------------------------------------------- 42
EGFR            -------------------------------------------------- 42
HER2/ERBB2      -------------------------------------------------- 42
HER4/ERBB4      -------------------------------------------------- 42
HER3/ERBB3      -------------------------------------------------- 42
ITK             -------------------------------------------------- 36
TEC             -------------------------------------------------- 36
TXK             -------------------------------------------------- 36
BMX             -------------------------------------------------- 36
1K2PA           -------------------------------------------------- 36
BTK             -------------------------------------------------- 36
CCK4            -------------------------------------------------- 42
ROR1            -------------------------------------------------- 42
ROR2            -------------------------------------------------- 43
MUSK            -------------------------------------------------- 43
TRKA            -------------------------------------------------- 42
TRKB            -------------------------------------------------- 42
TRKC            -------------------------------------------------- 43
DDR1            -------------------------------------------------- 54
DDR2            -------------------------------------------------- 54
RYK             -------------------------------------------------- 43
JAK1            -SGG---------------------------------------------- 41
JAK2            -STE---------------------------------------------- 41
JAK3            -SGP---------------------------------------------- 41
ACK             LSQP---------------------------------------------- 43
TYK2            --GP---------------------------------------------- 42
TNK1            PMG----------------------------------------------- 44
EPHA1           -------------------------------------------------- 41
EPHA10          -------------------------------------------------- 41
FAK             -------------------------------------------------- 41
EPHB6           -------------------------------------------------- 41
EPHA2           -------------------------------------------------- 42
EPHA8           -------------------------------------------------- 41
EPHA6           -------------------------------------------------- 41
EPHB1           -------------------------------------------------- 41
EPHB2           -------------------------------------------------- 41
EPHB3           -------------------------------------------------- 41
EPHB4           -------------------------------------------------- 41
EPHA7           -------------------------------------------------- 41
EPHA4           -------------------------------------------------- 41
EPHA3           -------------------------------------------------- 41
EPHA5           -------------------------------------------------- 41
PYK2            -------------------------------------------------- 41
CSK             DATAQ--------------------------------------------- 37
CTK             DVTAQ--------------------------------------------- 37
1IEPA           TMEVE--------------------------------------------- 40
ABL             TMEVE--------------------------------------------- 40
ARG             TMEVE--------------------------------------------- 40
BRK             NLLHQ--------------------------------------------- 39
SRM             NMKLT--------------------------------------------- 39
FRK             SMDPN--------------------------------------------- 39
FGR             TMSPK--------------------------------------------- 39
FYN             TMSPE--------------------------------------------- 39
SRC             TMSPE--------------------------------------------- 39
YES             TMMPE--------------------------------------------- 39
HCK             SMSVE--------------------------------------------- 39
LYN             TMSVQ--------------------------------------------- 39
3LCK            SMSPD--------------------------------------------- 39
LCK             SMSPD--------------------------------------------- 39
BLK             TMSPE--------------------------------------------- 39
FER             ELKI---------------------------------------------- 41
FES             DLK-A--------------------------------------------- 42
SYK             PA------------------------------------------------ 42
ZAP70           KA------------------------------------------------ 41
FGFR1           E------------------------------------------------- 45
FGFR2           E------------------------------------------------- 45
FGFR3           D------------------------------------------------- 45
FGFR4           D------------------------------------------------- 45
RET             P------------------------------------------------- 43
TIE1            E------------------------------------------------- 40
1FVRA           K------------------------------------------------- 40
TIE2            K------------------------------------------------- 40
FLT1            A------------------------------------------------- 43
KDR             H------------------------------------------------- 43
KDR_AVE         H------------------------------------------------- 43
FLT4            A------------------------------------------------- 43
FMS             A------------------------------------------------- 43
FLT3            S------------------------------------------------- 43
KIT             L------------------------------------------------- 43
PDGFRA          S------------------------------------------------- 43
PDGFRB          S------------------------------------------------- 43
MER             H------------------------------------------------- 42
AXL             R------------------------------------------------- 41
TYRO3           S------------------------------------------------- 42
MET             I------------------------------------------------- 41
RON             M------------------------------------------------- 41
HH498           S-K----------------------------------------------- 38
LZK             -------------------------------------------------- 36
DLK             -------------------------------------------------- 36
MLK1            DIS----------------------------------------------- 39
MLK3            DIS----------------------------------------------- 39
MLK2            DPA----------------------------------------------- 39
MLK4            DAA----------------------------------------------- 39
ZAK             -------------------------------------------------- 33
TAK1            --E----------------------------------------------- 33
KSR1            --Q----------------------------------------------- 36
KSR2            --E----------------------------------------------- 36
ARAF            --A----------------------------------------------- 36
RAF1            --P----------------------------------------------- 36
BRAF            --P----------------------------------------------- 36
LRRK2           -------------------------------------------------- 33
ANKRD3          --D----------------------------------------------- 39
SGK288          AAS----------------------------------------------- 38
RIPK2           LLD----------------------------------------------- 40
RIPK3           -------------------------------------------------- 34
MLKL            SIA----------------------------------------------- 34
ANPA            -------------------------------------------------- 41
ANPB            -------------------------------------------------- 41
CYGD            A------------------------------------------------- 40
CYGF            DLK----------------------------------------------- 54
TBCK            -------------------------------------------------- 22
ERK1            QTYC---------------------------------------------- 41
3ERK            QTYC---------------------------------------------- 41
ERK2            QTYC---------------------------------------------- 41
ERK5            VTNA---------------------------------------------- 42
1JNK            QTHA---------------------------------------------- 42
1PMNA           QTHA---------------------------------------------- 42
JNK3            QTHA---------------------------------------------- 42
JNK1            QTHA---------------------------------------------- 42
JNK2            QTHA---------------------------------------------- 42
1P38            IIHA---------------------------------------------- 42
P38A            IIHA---------------------------------------------- 42
P38B            LIHA---------------------------------------------- 42
P38D            EIFA---------------------------------------------- 42
P38G            ELFA---------------------------------------------- 42
NLK             LVSC---------------------------------------------- 42
ERK7            KTDAQDMGFLLAPPTHTPVF------------------------------ 58
ERK3            S--V---------------------------------------------- 40
ERK4            S--M---------------------------------------------- 40
ICK             W-------EE---------------------------------------- 41
MAK             WD-------E---------------------------------------- 41
PCTAIRE1        ------EGAP---------------------------------------- 41
PCTAIRE2        ------EGAP---------------------------------------- 41
PCTAIRE3        ------EGAP---------------------------------------- 41
PFTAIRE1        ------EGTP---------------------------------------- 41
PFTAIRE2        ------EGVP---------------------------------------- 41
CDC2            ------EGVP---------------------------------------- 42
1HCL            ------EGVP---------------------------------------- 38
CDK2            ------EGVP---------------------------------------- 42
CDK3            ------EGVP---------------------------------------- 42
CDK5            ------EGVP---------------------------------------- 42
CDK7            EAK---DGIN---------------------------------------- 45
CDK4            GGG---GGLP---------------------------------------- 45
1BLXA           ------EGMP---------------------------------------- 43
CDK6            ------EGMP---------------------------------------- 43
PITSLRE         ------EGFP---------------------------------------- 42
CDK10           ------DGIP---------------------------------------- 42
CDK9            ------EGFP---------------------------------------- 42
CHED            ------EGFP---------------------------------------- 42
CRK7            ------EGFP---------------------------------------- 42
CCRK            ------DGFP---------------------------------------- 42
CDK11           ------TGIS---------------------------------------- 41
CDK8            ------TGIS---------------------------------------- 41
IKKA            K------------------------------------------------- 39
IKKB            R------------------------------------------------- 39
1PHK            SFSAEEVQE----------------------------------------- 47
PHKG1           SFSPEEVRE----------------------------------------- 47
PHKG2           -LSPEQLEE----------------------------------------- 46
CAMK2A          -LSAR--------------------------------------------- 40
CAMK2B          -LSAR--------------------------------------------- 40
CAMK2G          -LSAR--------------------------------------------- 40
CAMK2D          -LSAR--------------------------------------------- 40
CASK            S-SPGL-------------------------------------------- 43
1IA8A           -------------------------------------------------- 36
CHK1            D------------------------------------------------- 39
CLK1            -----NVDR----------------------------------------- 38
CLK4            -----NVGR----------------------------------------- 37
CLK2            -----NVEK----------------------------------------- 38
CLK3            -----NVGK----------------------------------------- 38
MAP2K5          EL------------------------------------------------ 40
MAP2K3          QE------------------------------------------------ 40
MAP2K6          QE------------------------------------------------ 40
MAP2K4          KE------------------------------------------------ 40
MAP2K7          EE------------------------------------------------ 40
MAP2K1          AI------------------------------------------------ 40
MAP2K2          AI------------------------------------------------ 40
CDKL5           E------------------------------------------------- 39
CDKL1           P------------------------------------------------- 39
CDKL4           P------------------------------------------------- 39
CDKL2           K------------------------------------------------- 39
CDKL3           S------------------------------------------------- 39
1I09B           -------------------------------------------------- 35
GSK3B           -------------------------------------------------- 35
1J1BA           -------------------------------------------------- 35
GSK3A           -------------------------------------------------- 35
LATS1           LRNQ---------------------------------------------- 42
LATS2           NRNQ---------------------------------------------- 42
NDR1            EKEQ---------------------------------------------- 42
NDR2            EKEQ---------------------------------------------- 42
MAST1           LRNQ---------------------------------------------- 42
MAST4           LRNQ---------------------------------------------- 42
MAST2           LRNQ---------------------------------------------- 42
MAST3           LRNQ---------------------------------------------- 42
MRCKA           KRAE---------------------------------------------- 42
MRCKB           KRAE---------------------------------------------- 42
DMPK2           KRAE---------------------------------------------- 42
DMPK1           KRGE---------------------------------------------- 42
ROCK1           KRSD---------------------------------------------- 42
ROCK2           KRSD---------------------------------------------- 42
CRIK            AQEQ---------------------------------------------- 42
MASTL           NKNM---------------------------------------------- 40
1O6LA           AK-DE--------------------------------------------- 42
AKT2            AK-DE--------------------------------------------- 42
AKT1            AK-DE--------------------------------------------- 42
AKT3            AK-DE--------------------------------------------- 42
MSK1            QKAKT--------------------------------------------- 46
MSK2            QRAKT--------------------------------------------- 46
P70S6K          RNAKD--------------------------------------------- 46
P70S6KB         RNAKD--------------------------------------------- 46
RSK1            --VRD--------------------------------------------- 44
RSK3            --VRD--------------------------------------------- 44
RSK2            --VRD--------------------------------------------- 44
RSK4            --VRD--------------------------------------------- 44
1FOTA           RL-KQ--------------------------------------------- 42
1CDKA           KL-KQ--------------------------------------------- 42
PKACA           KL-KQ--------------------------------------------- 42
PKACB           KL-KQ--------------------------------------------- 42
PKACG           KM-KQ--------------------------------------------- 42
PRKX            RL-KQ--------------------------------------------- 42
PRKY            RR-KQ--------------------------------------------- 42
PKCA            QD-DD--------------------------------------------- 42
PKCB            QD-DD--------------------------------------------- 42
PKCG            QD-DD--------------------------------------------- 42
PKCE            QD-DD--------------------------------------------- 42
PKCH            QD-DD--------------------------------------------- 42
PKCD            ID-DD--------------------------------------------- 42
PKCT            MD-DD--------------------------------------------- 42
PKCI            DD-ED--------------------------------------------- 42
PKCZ            DD-ED--------------------------------------------- 42
PKN1            AR-DE--------------------------------------------- 42
PKN2            AR-DE--------------------------------------------- 42
PKN3            SR-DE--------------------------------------------- 42
SGK             KK-KE--------------------------------------------- 42
SGK2            KK-KE--------------------------------------------- 42
SGK3            NR-KE--------------------------------------------- 42
PKG1            DT-RQ--------------------------------------------- 43
PKG2            DT-KQ--------------------------------------------- 42
AURB            K--E---------------------------------------------- 40
AURC            K--E---------------------------------------------- 40
AURA            K--A---------------------------------------------- 40
AURORA2_AVE     K--A---------------------------------------------- 40
PLK1            K--P---------------------------------------------- 40
PLK2            K--P---------------------------------------------- 40
PLK3            K--P---------------------------------------------- 40
PLK4            K--A---------------------------------------------- 40
NEK11           ELNP---------------------------------------------- 42
YANK1           ER------------------------------------------------ 40
YANK2           ER------------------------------------------------ 40
YANK3           ER------------------------------------------------ 40
SGK494          QR------------------------------------------------ 40
DOMAIN2_MSK1    ----------AN-------------------------------------- 39
DOMAIN2_MSK2    ----------AN-------------------------------------- 33
DOMAIN2_RSK1    -----------D-------------------------------------- 38
DOMAIN2_RSK2    -----------D-------------------------------------- 38
DOMAIN2_RSK3    -----------D-------------------------------------- 38
DOMAIN2_RSK4    -----------D-------------------------------------- 38
DRAK1           Q--D----CRME-------------------------------------- 44
DRAK2           Q------DCRAE-------------------------------------- 44
1JKSA           S--SRRGVSRED-------------------------------------- 48
DAPK1           S--SRRGVSRED-------------------------------------- 48
DAPK3           S--SRRGVSREE-------------------------------------- 48
DAPK2           A--SRRGVSREE-------------------------------------- 48
SGK085          --------DKEE-------------------------------------- 42
CAMLCK          --------DRED-------------------------------------- 42
SKMLCK          --------DKEM-------------------------------------- 42
SMMLCK          --------EKEN-------------------------------------- 42
1KOBA           --------DKYT-------------------------------------- 42
1TKIA           --------DQVL-------------------------------------- 41
TTN             --------DQVL-------------------------------------- 41
PKD1            T--K----QESQ-------------------------------------- 44
PKD3            T--K----QESQ-------------------------------------- 44
PKD2            T--K----QESQ-------------------------------------- 44
PSKH1           G--------REV-------------------------------------- 42
PSKH2           G--------REA-------------------------------------- 42
CAMK1A          G--KEG-----S-------------------------------------- 43
CAMK1D          G--KES-----S-------------------------------------- 43
CAMK1B          G--KEA-----L-------------------------------------- 43
CAMK1G          R--------DSS-------------------------------------- 42
CAMK4           --------DKKI-------------------------------------- 40
DCAMKL1         G--KEH-----M-------------------------------------- 43
DCAMKL2         G--KEH-----L-------------------------------------- 43
DCAMKL3         G--KED-----M-------------------------------------- 43
CHK2            IGSAREADPALN-------------------------------------- 50
MAPKAPK2        -------------------------------------------------- 37
MAPKAPK3        -------------------------------------------------- 37
MAPKAPK5        -------------------------------------------------- 37
MNK1            S--------RSR-------------------------------------- 43
MNK2            I--------RSR-------------------------------------- 42
VACAMKL         K-------VRKA-------------------------------------- 43
GCK             -------------------------------------------------- 37
KHS1            -------------------------------------------------- 37
KHS2            -------------------------------------------------- 37
HPK1            -------------------------------------------------- 37
MST1            -------------------------------------------------- 37
MST2            -------------------------------------------------- 37
MST3            -------------------------------------------------- 37
YSK1            -------------------------------------------------- 37
MST4            -------------------------------------------------- 37
LOK             -------------------------------------------------- 37
SLK             -------------------------------------------------- 37
MAP3K4          -------------------------------------------------- 37
MAP3K2          -------------------------------------------------- 37
MAP3K3          -------------------------------------------------- 37
MAP3K8          -------------------------------------------------- 36
MAP3K5          -------------------------------------------------- 42
MAP3K7          -------------------------------------------------- 35
MAP3K6          -------------------------------------------------- 32
PAK1            -------------------------------------------------- 37
PAK3            -------------------------------------------------- 37
PAK2            -------------------------------------------------- 37
PAK4            -------------------------------------------------- 37
PAK5            -------------------------------------------------- 37
PAK6            -------------------------------------------------- 37
OSR1            -------------------------------------------------- 37
STLK3           -------------------------------------------------- 37
TAO1            -------------------------------------------------- 36
TAO3            -------------------------------------------------- 36
TAO2            -------------------------------------------------- 36
MYO3A           -------------------------------------------------- 37
MYO3B           -------------------------------------------------- 37
ZC1/HGK         -------------------------------------------------- 37
ZC3/MINK        -------------------------------------------------- 37
ZC2/TNIK        -------------------------------------------------- 37
ZC4/NRK         LPEIGRRVRVNKYQKSV--------------------------------- 55
MAP3K1          ----------------T--------------------------------- 38
GAK             ---E---------------------------------------------- 38
SGK495          -------------------------------------------------- 0
TRB1            -------------------------------------------------- 30
TRB2            -------------------------------------------------- 35
TRB3            -------------------------------------------------- 32
SSTK            P--D---------------------------------------------- 40
TSSK3           S--E---------------------------------------------- 40
TSSK1           A--D---------------------------------------------- 40
TSSK2           T--D---------------------------------------------- 40
TSSK4           D--D---------------------------------------------- 40
HUNK            KDTY---------------------------------------------- 43
SNRK            T--L---------------------------------------------- 40
NIM1            Q--K---------------------------------------------- 40
MELK            S------------------------------------------------- 39
BRSK1           E--S---------------------------------------------- 40
BRSK2           E--S---------------------------------------------- 40
MARK1           P--T---------------------------------------------- 40
MARK2           S--S---------------------------------------------- 40
MARK3           P--T---------------------------------------------- 40
MARK4           P--S---------------------------------------------- 40
QIK             A--V---------------------------------------------- 40
SIK             S--S---------------------------------------------- 40
QSK             E--E---------------------------------------------- 40
AMPKA1          SL-D---------------------------------------------- 41
AMPKA2          SL-D---------------------------------------------- 41
NUAK1           DE-Q---------------------------------------------- 41
NUAK2           DE-Q---------------------------------------------- 40
BIKE            D------------------------------------------------- 38
AAK1            ---H---------------------------------------------- 37
LIMK1           ----E--------------------------------------------- 37
LIMK2           ----E--------------------------------------------- 37
TESK1           ----P--------------------------------------------- 35
TESK2           ----S--------------------------------------------- 31
WNK1            ----K--------------------------------------------- 39
WNK3            ----K--------------------------------------------- 39
WNK2            ----K--------------------------------------------- 39
WNK4            ----R--------------------------------------------- 39
NEK10           FGKDK--------------------------------------------- 43
NEK6            ---DA--------------------------------------------- 40
NEK7            ---DA--------------------------------------------- 40
NEK2            ----E--------------------------------------------- 39
NEK1            ----S--------------------------------------------- 39
NEK5            ----I--------------------------------------------- 39
NEK3            ----F--------------------------------------------- 38
NEK4            ----S--------------------------------------------- 39
NEK8            ----K--------------------------------------------- 39
NEK9            ----E--------------------------------------------- 39
NRBP1           NY--K--------------------------------------------- 44
NRBP2           AF--A--------------------------------------------- 44
CLIK1           N------------------------------------------------- 39
CLIK1L          N------------------------------------------------- 39
STK33           SSA----------------------------------------------- 41
DOMAIN2_GCN2    --------LLYEWVLQWQKKMGP--------------------------- 44
SCYL1           -------------------------------------------------- 19
SCYL3           -------------------------------------------------- 22
DOMAIN2_JAK1    -------------------------------------------------- 27
DOMAIN2_TYK2    ---------PEEGKMDDEDPLVP--------------------------- 41
DOMAIN2_JAK2    -------------------------------------------------- 27
DOMAIN2_JAK3    -------------------------------------------------- 27
ILK             -----------VKVLKVRDWS----------------------------- 36
LRRK1           ------------------------------VKRFHIKKFKNFANVPADTM 47
PBK             SPW-------------------------------AVKKINPICNDHYRS- 45
WEE1            -----------YAIKRSKKPLAG--------------------------- 38
WEE1B           -----------YAIKRSMKTFTE--------------------------- 38
SGK071          -------------------------------------------------- 17
PIK3R4          -----------VKVFAIQDPTLP--------------------------- 38
MSSK1           -------------------------------------------------- 17
SRPK1           -------------------------------------------------- 17
SRPK2           -------------------------------------------------- 17
RSKL1           -------------------------------------------------- 11
RSKL2           ERL---------TIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSH 76
SGK396          ------------------------------LKGYS---------VDVDTE 35
VRK1            ------------------------------SDAPCVVKVEPSDNGPLFTE 47
VRK2            ------------------------------KDARHVVKVEYQENGPLFSE 45
VRK3            -------------------------------------------------- 0
BUB1            ------AKNKQKFVLKVQKPAN---------------------------P 42
BUBR1           LFWVAPRNSAELTVIKVSSQPV---------------------------P 50
SGK196          -----------LSQLTSL-------------------------------- 33
SGK493          ------------------------------LKAVDFSGHDLGSCVREFGV 44
                                                                  

DYRK1A          ------------------------------------------A----QIE 45
DYRK1B          ------------------------------------------A----QIE 45
DYRK2           ------------------------------------------A----AEE 45
DYRK3           ------------------------------------------A----AEE 45
DYRK4           ------------------------------------------A----LME 45
HIPK1           ------------------------------------------G----QIE 45
HIPK2           ------------------------------------------G----QIE 45
HIPK3           ------------------------------------------G----QIE 45
HIPK4           ------------------------------------------I----KNE 45
PRP4            ------------------------------------------G----LKE 46
MOK             ------------------------------------------VNN--LRE 47
1A6O            ------------------------------------------I----KRE 43
1LPUA           ------------------------------------------I----KRE 43
CK2A1           ------------------------------------------I----KRE 43
CK2A1-RS        ------------------------------------------I----KRE 43
CK2A2           ------------------------------------------I----KRE 43
HSER            ------------------------------------------Q----KIE 44
SLOB            ------------------------------------------SDKDFQCL 49
CDC7            ---------------------------------------------RIAAE 47
1CSN            ----------------------------------------------LRDE 44
CK1G1           ----------------------------------------------LHLE 44
CK1G3           ----------------------------------------------LHLE 44
CK1G2           ----------------------------------------------LHLE 44
CK1A            ----------------------------------------------LLYE 44
CK1A2           ----------------------------------------------LLYE 44
1CKJA           ----------------------------------------------LHIE 44
CK1D            ----------------------------------------------LHIE 44
CK1E            ----------------------------------------------LHIE 44
TTBK1           ----------------------------------------------LKME 44
TTBK2           ----------------------------------------------LKME 44
TLK1            ------------------------------------------YHKHACRE 53
TLK2            ------------------------------------------YHKHACRE 53
GPRK4           ------------------------------------------GEAMALNE 49
GPRK6           ------------------------------------------GEAMALNE 49
GPRK5           ------------------------------------------GESMALNE 49
RHOK            ------------------------------------------GYQGAMVE 49
GPRK7           ------------------------------------------GEKMALLE 49
BARK1           ------------------------------------------GETLALNE 49
BARK2           ------------------------------------------GETLALNE 49
TTK             ------------------------------------------LDSY-RNE 47
RIPK1           ------------------------------------------NEA-LLEE 47
HASPIN          ------------------------------------------TFEEILPE 52
GCN2            ---------------------------------------------RIKGE 47
HRI             ---------------------------------------------KVLRE 48
KIS             -----------------------------------------AAEYGFRKE 54
PDK1            --------------------------------------------PYVTRE 49
PKR             ---------------------------------------------KAERE 42
PEK             ---------------------------------------------KVMRE 47
PRPK            -----------------------------------------ARLGRRRTV 50
DOMAIN2_OBSCN   -------------------------------------------TAVLR-E 45
DOMAIN2_SPEG    -------------------------------------------RRVLQ-E 45
LMR1            -------------------------------------------MQFLE-E 49
LMR2            -------------------------------------------DTFLK-N 49
LMR3            -------------------------------------------RKFIS-E 49
SGK307          ------------------------------------------------QQ 2
STLK5           -------------------------------------------VTFLQGE 50
STLK6           -------------------------------------------LKALQ-K 49
STLK6-RS        -------------------------------------------LKALQ-K 49
OBSCN           -------------------------------------------AQAYR-E 45
SPEG            -------------------------------------------ASARR-E 45
TRAD            -------------------------------------------EQAAH-E 45
TRIO            -------------------------------------------DQVTH-E 45
SGK223          -------------------------------------------VPALP-- 60
SGK269          -------------------------------------------QQYYH-S 46
ALK1            ------------------------------------------E-----TE 43
ALK2            ------------------------------------------E-----TE 43
IRAK4           -------------------------------------------KQQFDQE 48
BMPR2           ------------------------------------------E-----KN 43
TGFBR2          ------------------------------------------E-----KD 49
ACTR2           ------------------------------------------E-----YE 43
ACTR2B          ------------------------------------------E-----RE 43
1B6CB           ------------------------------------------E-----AE 43
TGFBR1          ------------------------------------------E-----AE 43
ALK4            ------------------------------------------E-----AE 43
ALK7            ------------------------------------------E-----AE 43
BMPR1A          ------------------------------------------E-----TE 43
BMPR1B          ------------------------------------------E-----TE 43
IRAK1           ------------------------------------------VKQSFLTE 48
IRAK2           --------------------------------------------RFFQAE 48
IRAK3           --------------------------------------------KRFLSE 48
MISR2           ---------------------------------------------QAERA 43
MYT1            --------------------------------------------ARKLAE 48
SBK             --------------------------------------------KNFLRE 45
SGK110          --------------------------------------------STFLRE 45
SGK069          --------------------------------------------RGFLYE 45
SGK496          --------------------------------------------NDLALE 46
NIK             --------------------------------------------EVFRAE 40
SGK424          -------------------------------------------------- 0
SURTK106        --------------------------------------------QDFLGR 51
IKKE            ------------------------------------------PREVQVRE 47
TBK1            ------------------------------------------PVDVQMRE 47
MOS             ------------------------------------CTKNRLASRRSFWA 46
LKB1            --------------------------------------------ANVKKE 50
CAMKK1          ------------------------------------PAKQLLPLERVYQE 81
CAMKK2          ------------------------------------CIQPRGPIEQVYQE 72
PASK            ------------------------------------CWIEDPKLGKVTLE 54
PIM1            -------------------------------------WGELPNGTRVPME 52
PIM3            -------------------------------------WGSLG-GATVPLE 51
PIM2            -------------------------------------WSPLSDSVTCPLE 52
COT             -----------------------------------------------PSD 43
SCYL2           --------------------------------------EKDQIIDSLKRG 58
FUSED           -------------------------------------GRSEKELRNLQRE 48
ULK1            -------------------------------------NLAKSQTL-LGKE 48
ULK2            -------------------------------------NLSKSQIL-LGKE 48
ULK3            -------------------------------------SLNKASVENLLTE 49
ULK4            ---------------------------------------DKCRRPEITNW 43
IRE1            -------------------------------------CFSF-----ADRE 42
IRE2            -------------------------------------CFG-----LVRRE 42
RNASEL          ---------------------------------------------RAQRE 36
MPSK1           -------------------------------------CHEQQDREEAQRE 46
PINK1           -----------------------------------ALAGEYGAVTYRKSK 107
ALK             -----------------------------------------QDELDFLME 52
LTK             -----------------------------------------QDELDFLME 52
ROS             -----------------------------------------QEKIEFLKE 53
IGF1R           -----------------------------------------RERIEFLNE 52
1IR3A           -----------------------------------------RERIEFLNE 52
INSR            -----------------------------------------RERIEFLNE 52
IRR             -----------------------------------------RECIEFLKE 52
1M14A           -----------------------------------------KANKEILDE 51
EGFR            -----------------------------------------KANKEILDE 51
HER2/ERBB2      -----------------------------------------KANKEILDE 51
HER4/ERBB4      -----------------------------------------KANVEFMDE 51
HER3/ERBB3      -----------------------------------------QSFQAVTDH 51
ITK             ------------------------------------------SEEDFIEE 44
TEC             ------------------------------------------CEEDFIEE 44
TXK             ------------------------------------------SEEDFIEE 44
BMX             ------------------------------------------SEDEFFQE 44
1K2PA           ------------------------------------------SEDEFIEE 44
BTK             ------------------------------------------SEDEFIEE 44
CCK4            -----------------------------------------QQQLDFRRE 51
ROR1            -----------------------------------------QQWMEFQQE 51
ROR2            -----------------------------------------PLREEFRHE 52
MUSK            -----------------------------------------DMQADFQRE 52
TRKA            -----------------------------------------SARQDFQRE 51
TRKB            -----------------------------------------NARKDFHRE 51
TRKC            ------------------------------------------ARKDFQRE 51
DDR1            -----------------------------------------NARNDFLKE 63
DDR2            -----------------------------------------NARNDFLKE 63
RYK             -----------------------------------------IQVTMMLTE 52
JAK1            -----------------------------------------NHIADLKKE 50
JAK2            -----------------------------------------EHLRDFERE 50
JAK3            -----------------------------------------DQQRDFQRE 50
ACK             -----------------------------------------EAMDDFIRE 52
TYK2            -----------------------------------------QHRSGWKQE 51
TNK1            -----------------------------------------TELGDFLRE 53
EPHA1           -----------------------------------------GQWWNFLRE 50
EPHA10          -----------------------------------------SQRLGFLAE 50
FAK             -----------------------------------------SVREKFLQE 50
EPHB6           -----------------------------------------SLQMTFLGR 50
EPHA2           -----------------------------------------KQRVDFLGE 51
EPHA8           -----------------------------------------RQRRDFLSE 50
EPHA6           -----------------------------------------RQRRDFLRE 50
EPHB1           -----------------------------------------KQRRDFLSE 50
EPHB2           -----------------------------------------KQRRDFLSE 50
EPHB3           -----------------------------------------RQRRDFLSE 50
EPHB4           -----------------------------------------RQRREFLSE 50
EPHA7           -----------------------------------------KQRRDFLCE 50
EPHA4           -----------------------------------------KQRRDFLSE 50
EPHA3           -----------------------------------------KQRRDFLGE 50
EPHA5           -----------------------------------------KQRRDFLGE 50
PYK2            -----------------------------------------DNKEKFMSE 50
CSK             --------------------------------------------AFLA-E 42
CTK             --------------------------------------------AFLD-E 42
1IEPA           --------------------------------------------EFLK-E 45
ABL             --------------------------------------------EFLK-E 45
ARG             --------------------------------------------EFLK-E 45
BRK             --------------------------------------------QMLQSE 45
SRM             --------------------------------------------DLAK-E 44
FRK             --------------------------------------------DFLR-E 44
FGR             --------------------------------------------AFLE-E 44
FYN             --------------------------------------------SFLE-E 44
SRC             --------------------------------------------AFLQ-E 44
YES             --------------------------------------------AFLQ-E 44
HCK             --------------------------------------------AFLA-E 44
LYN             --------------------------------------------AFLE-E 44
3LCK            --------------------------------------------AFLA-E 44
LCK             --------------------------------------------AFLA-E 44
BLK             --------------------------------------------AFLG-E 44
FER             --------------------------------------------KFLQ-E 46
FES             --------------------------------------------KFLQ-E 47
SYK             ------------------------------------------LKDELLAE 50
ZAP70           ------------------------------------------DTEEMMRE 49
FGFR1           -----------------------------------------KDLSDLISE 54
FGFR2           -----------------------------------------KDLSDLVSE 54
FGFR3           -----------------------------------------KDLSDLVSE 54
FGFR4           -----------------------------------------KDLADLVSE 54
RET             -----------------------------------------SELRDLLSE 52
TIE1            -----------------------------------------NDHRDFAGE 49
1FVRA           -----------------------------------------DDHRDFAGE 49
TIE2            -----------------------------------------DDHRDFAGE 49
FLT1            -----------------------------------------SEYKALMTE 52
KDR             -----------------------------------------SEHRALMSE 52
KDR_AVE         -----------------------------------------SEHRALMSE 52
FLT4            -----------------------------------------SEHRALMSE 52
FMS             -----------------------------------------DEKEALMSE 52
FLT3            -----------------------------------------SEREALMSE 52
KIT             -----------------------------------------TEREALMSE 52
PDGFRA          -----------------------------------------SEKQALMSE 52
PDGFRB          -----------------------------------------SEKQALMSE 52
MER             -----------------------------------------REIEEFLSE 51
AXL             -----------------------------------------SELEDFLSE 50
TYRO3           -----------------------------------------SDIEEFLRE 51
MET             -----------------------------------------GEVSQFLTE 50
RON             -----------------------------------------QQVEAFLRE 50
HH498           -----------------------------------------SDVDMFCRE 47
LZK             -------------------------------------------------D 37
DLK             -------------------------------------------------D 37
MLK1            -----------------------------------------QTIENVRQE 48
MLK3            -----------------------------------------VTAESVRQE 48
MLK2            -----------------------------------------VTAEQVCQE 48
MLK4            -----------------------------------------AAAESVRRE 48
ZAK             ---------------------------------------------KIEKE 38
TAK1            -----------------------------------------SERKAFIVE 42
KSR1            -----------------------------------------DHLKLFKKE 45
KSR2            -----------------------------------------DQLKAFKRE 45
ARAF            -----------------------------------------EQAQAFKNE 45
RAF1            -----------------------------------------EQFQAFRNE 45
BRAF            -----------------------------------------QQLQAFKNE 45
LRRK2           -----------------------------------------TSLRLLRQE 42
ANKRD3          -----------------------------------------RERMELLEE 48
SGK288          -----------------------------------------SDVNYLIEE 47
RIPK2           -----------------------------------------SERKDVLRE 49
RIPK3           --------------------------------------------KAISRE 40
MLKL            -----------------------------------------IVRQTFNKE 43
ANPA            ------------------------------------------LTRKVLFE 49
ANPB            ------------------------------------------LTRQVLFE 49
CYGD            ------------------------------------------IRPATKTA 48
CYGF            -----------------------------------------SIKSRASDV 63
TBCK            ------------------------------------------------GR 24
ERK1            --------------------------------------------QRTLRE 47
3ERK            --------------------------------------------QRTLRE 47
ERK2            --------------------------------------------QRTLRE 47
ERK5            --------------------------------------------KRTLRE 48
1JNK            --------------------------------------------KRAYRE 48
1PMNA           --------------------------------------------KRAYRE 48
JNK3            --------------------------------------------KRAYRE 48
JNK1            --------------------------------------------KRAYRE 48
JNK2            --------------------------------------------KRAYRE 48
1P38            --------------------------------------------KRTYRE 48
P38A            --------------------------------------------KRTYRE 48
P38B            --------------------------------------------RRTYRE 48
P38D            --------------------------------------------KRAYRE 48
P38G            --------------------------------------------KRAYRE 48
NLK             --------------------------------------------KRVFRE 48
ERK7            -----------------------------------------LSLQRTFRE 67
ERK3            --------------------------------------------KHALRE 46
ERK4            --------------------------------------------KHALRE 46
ICK             --------------------------------------------CMNLRE 47
MAK             --------------------------------------------CMNLRE 47
PCTAIRE1        --------------------------------------------CTAIRE 47
PCTAIRE2        --------------------------------------------CTAIRE 47
PCTAIRE3        --------------------------------------------CTAIRE 47
PFTAIRE1        --------------------------------------------FTAIRE 47
PFTAIRE2        --------------------------------------------FTAIRE 47
CDC2            --------------------------------------------STAIRE 48
1HCL            --------------------------------------------STAIRE 44
CDK2            --------------------------------------------STAIRE 48
CDK3            --------------------------------------------STAIRE 48
CDK5            --------------------------------------------SSALRE 48
CDK7            --------------------------------------------RTALRE 51
CDK4            --------------------------------------------ISTVRE 51
1BLXA           --------------------------------------------LSTIRE 49
CDK6            --------------------------------------------LSTIRE 49
PITSLRE         --------------------------------------------ITSLRE 48
CDK10           --------------------------------------------ISSLRE 48
CDK9            --------------------------------------------ITALRE 48
CHED            --------------------------------------------ITAIRE 48
CRK7            --------------------------------------------ITAIRE 48
CCRK            --------------------------------------------NQALRE 48
CDK11           --------------------------------------------MSACRE 47
CDK8            --------------------------------------------MSACRE 47
IKKA            ------------------------------------------NRERWCHE 47
IKKB            ------------------------------------------NRERWCLE 47
1PHK            ------------------------------------------LREATLKE 55
PHKG1           ------------------------------------------LREATLKE 55
PHKG2           ------------------------------------------VREATRRE 54
CAMK2A          ------------------------------------------DHQKLERE 48
CAMK2B          ------------------------------------------DHQKLERE 48
CAMK2G          ------------------------------------------DHQKLERE 48
CAMK2D          ------------------------------------------DHQKLERE 48
CASK            ------------------------------------------STEDLKRE 51
1IA8A           ------------------------------------------CPENIKKE 44
CHK1            ------------------------------------------CPENIKKE 47
CLK1            ------------------------------------------YCEAARSE 46
CLK4            ------------------------------------------YREAARSE 45
CLK2            ------------------------------------------YKEAARLE 46
CLK3            ------------------------------------------YREAARLE 46
MAP2K5          -------------------------------------------QKQIMSE 47
MAP2K3          -------------------------------------------QKRLLMD 47
MAP2K6          -------------------------------------------QKRLLMD 47
MAP2K4          -------------------------------------------QKQLLMD 47
MAP2K7          -------------------------------------------NKRILMD 47
MAP2K1          -------------------------------------------RNQIIRE 47
MAP2K2          -------------------------------------------RNQIIRE 47
CDKL5           -----------------------------------------EVKETTLRE 48
CDKL1           -----------------------------------------VIKKIALRE 48
CDKL4           -----------------------------------------VVKKIALRE 48
CDKL2           -----------------------------------------MVKKIAMRE 48
CDKL3           ------------------------------------------VNKIAMRE 47
1I09B           -------------------------------------------KRFKNRE 42
GSK3B           -------------------------------------------KRFKNRE 42
1J1BA           -------------------------------------------KRFKNRE 42
GSK3A           -------------------------------------------KRFKNRE 42
LATS1           -------------------------------------------VAHVKAE 49
LATS2           -------------------------------------------VAHVKAE 49
NDR1            -------------------------------------------VGHIRAE 49
NDR2            -------------------------------------------VAHIRAE 49
MAST1           -------------------------------------------IQQAFVE 49
MAST4           -------------------------------------------IQQAFVE 49
MAST2           -------------------------------------------IQQAFVE 49
MAST3           -------------------------------------------IQQVFVE 49
MRCKA           -------------------------------------------TACFREE 49
MRCKB           -------------------------------------------TACFREE 49
DMPK2           -------------------------------------------TACFREE 49
DMPK1           -------------------------------------------VSCFREE 49
ROCK1           -------------------------------------------SAFFWEE 49
ROCK2           -------------------------------------------SAFFWEE 49
CRIK            -------------------------------------------VSFFEEE 49
MASTL           -------------------------------------------THQVQAE 47
1O6LA           -------------------------------------------VAHTVTE 49
AKT2            -------------------------------------------VAHTVTE 49
AKT1            -------------------------------------------VAHTLTE 49
AKT3            -------------------------------------------VAHTLTE 49
MSK1            -------------------------------------------TEHTRTE 53
MSK2            -------------------------------------------QEHTRTE 53
P70S6K          -------------------------------------------TAHTKAE 53
P70S6KB         -------------------------------------------TAHTRAE 53
RSK1            -------------------------------------------RVRSKME 51
RSK3            -------------------------------------------RVRTKME 51
RSK2            -------------------------------------------RVRTKME 51
RSK4            -------------------------------------------RVRTKME 51
1FOTA           -------------------------------------------VEHTNDE 49
1CDKA           -------------------------------------------IEHTLNE 49
PKACA           -------------------------------------------IEHTLNE 49
PKACB           -------------------------------------------IEHTLNE 49
PKACG           -------------------------------------------VEHILNE 49
PRKX            -------------------------------------------EQHVHNE 49
PRKY            -------------------------------------------EQHVHNE 49
PKCA            -------------------------------------------VECTMVE 49
PKCB            -------------------------------------------VECTMVE 49
PKCG            -------------------------------------------VDCTLVE 49
PKCE            -------------------------------------------VDCTMTE 49
PKCH            -------------------------------------------VECTMTE 49
PKCD            -------------------------------------------VECTMVE 49
PKCT            -------------------------------------------VECTMVE 49
PKCI            -------------------------------------------IDWVQTE 49
PKCZ            -------------------------------------------IDWVQTE 49
PKN1            -------------------------------------------VESLMCE 49
PKN2            -------------------------------------------VDSLMCE 49
PKN3            -------------------------------------------IESLYCE 49
SGK             -------------------------------------------EKHIMSE 49
SGK2            -------------------------------------------QSHIMAE 49
SGK3            -------------------------------------------QKHIMAE 49
PKG1            -------------------------------------------QEHIRSE 50
PKG2            -------------------------------------------QEHVYSE 49
AURB            -----------------------------------------GVEHQLRRE 49
AURC            -----------------------------------------GLEHQLRRE 49
AURA            -----------------------------------------GVEHQLRRE 49
AURORA2_AVE     -----------------------------------------GVEHQLRRE 49
PLK1            -----------------------------------------HQREKMSME 49
PLK2            -----------------------------------------HQREKIDKE 49
PLK3            -----------------------------------------HQREKILNE 49
PLK4            -----------------------------------------GMVQRVKNE 49
NEK11           -----------------------------------------NETVQANLE 51
YANK1           -----------------------------------------NEVRNVFKE 49
YANK2           -----------------------------------------DEVRNVFRE 49
YANK3           -----------------------------------------DEVRNVFRE 49
SGK494          -----------------------------------------DTVRQCKEE 49
DOMAIN2_MSK1    ----------------------------------------------TQKE 43
DOMAIN2_MSK2    ----------------------------------------------TQRE 37
DOMAIN2_RSK1    ----------------------------------------------PSEE 42
DOMAIN2_RSK2    ----------------------------------------------PTEE 42
DOMAIN2_RSK3    ----------------------------------------------PSEE 42
DOMAIN2_RSK4    ----------------------------------------------PSEE 42
DRAK1           ----------------------------------------------IIHE 48
DRAK2           ----------------------------------------------ILHE 48
1JKSA           ----------------------------------------------IERE 52
DAPK1           ----------------------------------------------IERE 52
DAPK3           ----------------------------------------------IERE 52
DAPK2           ----------------------------------------------IERE 52
SGK085          ----------------------------------------------VKNE 46
CAMLCK          ----------------------------------------------VKNE 46
SKMLCK          ----------------------------------------------VLLE 46
SMMLCK          ----------------------------------------------IRQE 46
1KOBA           ----------------------------------------------VKNE 46
1TKIA           ----------------------------------------------VKKE 45
TTN             ----------------------------------------------VKKE 45
PKD1            ----------------------------------------------LRNE 48
PKD3            ----------------------------------------------LRNE 48
PKD2            ----------------------------------------------LRNE 48
PSKH1           ----------------------------------------------CESE 46
PSKH2           ----------------------------------------------CVSE 46
CAMK1A          ----------------------------------------------MENE 47
CAMK1D          ----------------------------------------------IENE 47
CAMK1B          ----------------------------------------------VENE 47
CAMK1G          ----------------------------------------------LENE 46
CAMK4           ----------------------------------------------VRTE 44
DCAMKL1         ----------------------------------------------IQNE 47
DCAMKL2         ----------------------------------------------IENE 47
DCAMKL3         ----------------------------------------------VDSE 47
CHK2            ----------------------------------------------VETE 54
MAPKAPK2        ----------------------------------------------ARRE 41
MAPKAPK3        ----------------------------------------------ARQE 41
MAPKAPK5        ----------------------------------------------ARNE 41
MNK1            ----------------------------------------------VFRE 47
MNK2            ----------------------------------------------VFRE 46
VACAMKL         ----------------------------------------------AKNE 47
GCK             -----------------------------------------DDISSLQQE 46
KHS1            -----------------------------------------DDFSLIQQE 46
KHS2            -----------------------------------------EDFAVVQQE 46
HPK1            -----------------------------------------DDVSTLQKE 46
MST1            -------------------------------------------LQEIIKE 44
MST2            -------------------------------------------LQEIIKE 44
MST3            ----------------------------------------EDEIEDIQQE 47
YSK1            ----------------------------------------EDEIEDIQQE 47
MST4            ----------------------------------------EDEIEDIQQE 47
LOK             -----------------------------------------EELEDYIVE 46
SLK             -----------------------------------------EELEDYMVE 46
MAP3K4          ---------------------------------------DHKTIKETADE 48
MAP3K2          -----------------------------------SP-ETSKEVNALECE 51
MAP3K3          -----------------------------------SP-ETSKEVSALECE 51
MAP3K8          -----------------------------------NKLAAEKEYRKLQEE 51
MAP3K5          -----------------------------------------RYSQPLHEE 51
MAP3K7          -----------------------------------------RYSQPLHEE 44
MAP3K6          -----------------------------------------RFSQPLHEE 41
PAK1            -----------------------------------------PKKELIINE 46
PAK3            -----------------------------------------PKKELIINE 46
PAK2            -----------------------------------------PKKELIINE 46
PAK4            -----------------------------------------QRRELLFNE 46
PAK5            -----------------------------------------QRRELLFNE 46
PAK6            -----------------------------------------QRRELLFNE 46
OSR1            ----------------------------------------QTSMDELLKE 47
STLK3           ----------------------------------------QTSMDELLKE 47
TAO1            ------------------------------------K-QSTEKWQDIIKE 49
TAO3            ------------------------------------K-QTHEKWQDILKE 49
TAO2            ------------------------------------K-QSNEKWQDIIKE 49
MYO3A           ------------------------------------------IDEEIEAE 45
MYO3B           ------------------------------------------MDEEIEAE 45
ZC1/HGK         ------------------------------------------EEEEIKLE 45
ZC3/MINK        ------------------------------------------EEEEIKQE 45
ZC2/TNIK        ------------------------------------------EEEEIKQE 45
ZC4/NRK         -----------------------------------GW-RYSDEEEDLRTE 69
MAP3K1          -----------------------------------SS-EQEEVVEALREE 52
GAK             -----------------------------------------KNRA-IIQE 46
SGK495          -------------------------------------------------- 0
TRB1            -----------------------------------------------DKI 33
TRB2            -----------------------------------------------ESL 38
TRB3            ----------------------------------------------LAVL 36
SSTK            -----------------------------------------FVNKFLPRE 49
TSSK3           -----------------------------------------FIQRFLPRE 49
TSSK1           -----------------------------------------FLEKFLPRE 49
TSSK2           -----------------------------------------FVERFLPRE 49
TSSK4           -----------------------------------------YLNKFLPRE 49
HUNK            -----------------------------------------VTK-NLRRE 51
SNRK            -----------------------------------------ATGH-LFQE 48
NIM1            -----------------------------------------TQRL-LSRE 48
MELK            -----------------------------------------DLPR-IKTE 47
BRSK1           -----------------------------------------VLMK-VERE 48
BRSK2           -----------------------------------------VLMK-VERE 48
MARK1           -----------------------------------------SLQK-LFRE 48
MARK2           -----------------------------------------SLQK-LFRE 48
MARK3           -----------------------------------------SLQK-LFRE 48
MARK4           -----------------------------------------SLQK-LFRE 48
QIK             -----------------------------------------NLEK-IYRE 48
SIK             -----------------------------------------NLEK-IYRE 48
QSK             -----------------------------------------NLKK-IFRE 48
AMPKA1          -----------------------------------------VVGK-IRRE 49
AMPKA2          -----------------------------------------VVGK-IKRE 49
NUAK1           -----------------------------------------DMVH-IRRE 49
NUAK2           -----------------------------------------DLMH-IRRE 48
BIKE            ------------------------------------------LNV-CKRE 45
AAK1            -----------------------------------------DLQV-CKRE 45
LIMK1           -------------------------------------ETQ----RTFLKE 46
LIMK2           -------------------------------------ETQ----KTFLTE 46
TESK1           -------------------------------------SNR----GNTLRE 44
TESK2           -------------------------------------SNR----ANMLKE 40
WNK1            -------------------------------------SER----QRFKEE 48
WNK3            -------------------------------------AEQ----QRFKEE 48
WNK2            -------------------------------------LER----QRFKEE 48
WNK4            -------------------------------------AER----QRFSEE 48
NEK10           -------------------------------------KDRDSSVRNIVSE 56
NEK6            -------------------------------------KAR----QDCVKE 49
NEK7            -------------------------------------KAR----ADCIKE 49
NEK2            -------------------------------------AEK----QMLVSE 48
NEK1            -------------------------------------KER----EESRRE 48
NEK5            -------------------------------------QEK----EASKKE 48
NEK3            -------------------------------------SNT----QNSRKE 47
NEK4            -------------------------------------RER----RAAEQE 48
NEK8            -------------------------------------EER----QAAQNE 48
NEK9            -------------------------------------KER----RDALNE 48
NRBP1           -------------------------------------LQE----EKVRAV 53
NRBP2           -------------------------------------AHE----EKIQTV 53
CLIK1           -------------------------------------------VELALAE 46
CLIK1L          -------------------------------------------VELALRE 46
STK33           -------------------------------------------VKLLERE 48
DOMAIN2_GCN2    FLTSQEKEKIDKCKKQIQG---------------------------TETE 67
SCYL1           ---------------------------------YDVKPGAEEQTQVAKAA 36
SCYL3           -------------------------------------------EDKVNKA 29
DOMAIN2_JAK1    ---------------------GTSEEKKIKVILKVLDPSHRDISLAFFEA 56
DOMAIN2_TYK2    ---------------------GRDRGQELRVVLKVLDPSHHDIALAFYET 70
DOMAIN2_JAK2    ------------------------QLHETEVLLKVLDKAHRNYSESFFEA 53
DOMAIN2_JAK3    -------------------------ARKTEVLLKVMDAKHKNCMESFLEA 52
ILK             ----------------------------------------TRKSRDFNEE 46
LRRK1           LRHLRATDA-------------------------------MKNFSEFRQE 66
PBK             -----------------------------------------VYQKRLMDE 54
WEE1            ---------------------------------------SVDEQNALREV 49
WEE1B           ---------------------------------------LSNENSALHEV 49
SGK071          ---------------------VEEMETKVKHVIKQVECMDDHYASQALEE 46
PIK3R4          --LTSYKQELEELK------------------------------------ 50
MSSK1           ---------------------CWDIQRK-RFVALKVVKSAGHYTETAVDE 45
SRPK1           ---------------------SWDIQGK-KFVAMKVVKSAEHYTETALDE 45
SRPK2           ---------------------CWDMQGK-RFVAMKVVKSAQHYTETALDE 45
RSKL1           ---------------------ASTDTLKTEEVLLFTDQTDD--------- 31
RSKL2           LLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPS----GHAPGQD 122
SGK396          AKVIERAATYHRAWRE---------------------------------- 51
VRK1            LKFYQRAAKPEQIQKWIRTRK----------------------------- 68
VRK2            LKFYQRVAKKDCIKKWIERKQ----------------------------- 66
VRK3            ------AAKPLQVNKWKKLYS-----------------------TPLLAI 21
BUB1            WEFYIGTQLMERLKPSMQHM------------------------------ 62
BUBR1           WDFYINLKLKERLNEDFDH------------------------------- 69
SGK196          -----------------------------------------EMKDDFLHG 42
SGK493          RRGCYRLA-----------------------------------AHKLLKE 59
                                                                  

DYRK1A          VR-LLELMN---KHDTEMKYYIVHL------------------------- 66
DYRK1B          LR-LLELMN---QHDTEMKYYIVHL------------------------- 66
DYRK2           IR-ILEHLR---KQDKDNTMNVIHM------------------------- 66
DYRK3           IR-ILEHLK---KQDKTGSMNVIHM------------------------- 66
DYRK4           LK-ILEALR---KKDKDNTYNVVHM------------------------- 66
HIPK1           VS-ILSRLS---SENAD-EYNLVRS------------------------- 65
HIPK2           VS-ILARLS---TESAD-DYNFVRA------------------------- 65
HIPK3           VS-ILARLS---TENAD-EYNFVRA------------------------- 65
HIPK4           LK-LLHCMR---GLDPE-EAHVIRF------------------------- 65
PRP4            LE-FLKKLN---DADPDDKFHCLRL------------------------- 67
MOK             IQ-ALRRLN---PHP-----NILML------------------------- 63
1A6O            IK-ILQNLC---GGP-----NIVKL------------------------- 59
1LPUA           IK-ILQNLC---GGP-----NIVKL------------------------- 59
CK2A1           IK-ILENLR---GGP-----NIITL------------------------- 59
CK2A1-RS        IK-ILENLR---GGP-----NIITL------------------------- 59
CK2A2           VK-ILENLR---GGT-----NIIKL------------------------- 59
HSER            LN-KLLQI------------------------------------------ 51
SLOB            IK-LLPSCL---------HPYIYRV------------------------- 64
CDC7            LQ-CLTVAG---GQD-----NVMGV------------------------- 63
1CSN            YR-TYKLLA---GCT-----GIPNV------------------------- 60
CK1G1           YR-FYKQLG---SAGE----GLPQV------------------------- 61
CK1G3           YR-FYKQLG---S-GD----GIPQV------------------------- 60
CK1G2           YR-FYKQL----SATE----GVPQV------------------------- 60
CK1A            SK-LYKILQ---GGV-----GIPHI------------------------- 60
CK1A2           SK-LYTILQ---GGV-----GIPHM------------------------- 60
1CKJA           SK-IYKMMQ---GGV-----GIPTI------------------------- 60
CK1D            SK-IYKMMQ---GGV-----GIPTI------------------------- 60
CK1E            SK-FYKMMQ---GGV-----GIPSI------------------------- 60
TTBK1           VA-VLKKLQ---GKD-----HVCRF------------------------- 60
TTBK2           VA-VLKKLQ---GKD-----HVCRF------------------------- 60
TLK1            YR-IHKELD---------HPRIVKL------------------------- 68
TLK2            YR-IHKELD---------HPRIVKL------------------------- 68
GPRK4           KR-ILEKVQ---S------RFVVSL------------------------- 64
GPRK6           KQ-ILEKVN---S------RFVVSL------------------------- 64
GPRK5           KQ-ILEKVN---S------QFVVNL------------------------- 64
RHOK            KK-ILMKVH---S------RFIVSL------------------------- 64
GPRK7           KE-ILEKVS---S------PFIVSL------------------------- 64
BARK1           RI-MLSLVS---T---GDCPFIVCM------------------------- 67
BARK2           RI-MLSLVS---T---GDCPFIVCM------------------------- 67
TTK             IA-YLNKLQ---QH----SDKIIRL------------------------- 64
RIPK1           AK-MMNRLR---H------SRVVKL------------------------- 62
HASPIN          II-ISKELS---LL----SGEVCNR------------------------- 69
GCN2            VT-LLSRLH----HE-----NIVRYYNAWIER-----HERP-----AGPG 77
HRI             VK-VLAGLQ----HP-----NIVGYHTAWIEHV-HVIQPRADR---AAIE 84
KIS             RA-ALEQLQ---GHR-----NIVTLYGVFTIH----FSPNVPSRCL---- 87
PDK1            RD-VMSRLD----HP-----FFVKLYFTF--------------------- 68
PKR             VK-ALAKLD----HV-----NIVHYNGCWDGFD----------------- 65
PEK             VK-ALAKLE----HP-----GIVRYFNAWLEAPPEKWQEKMDEIWLKDES 87
PRPK            QE-ARALLR---CRR-----AGISAPVVFFVD------------------ 73
DOMAIN2_OBSCN   YE-ALK---G-LRHP-----HLAQLHAAY---LS---------------- 66
DOMAIN2_SPEG    YE-VLR---T-LHHE-----RIMSLHEAY---IT---------------- 66
LMR1            VQ-PYR---A-LKHS-----NLLQCLAQC---AE---------------- 70
LMR2            GE-PYY---I-LQHP-----NILQCVGQC---VE---------------- 70
LMR3            AQ-PYR---S-LQHP-----NVLQCLGLC---VE---------------- 70
SGK307          RS-QF--------------------------------------------- 6
STLK5           LH-VSK---L-FNHP-----NIVPYRATF---IA---------------- 71
STLK6           AV-ILS---HFFRHP-----NITTYWTVF---TV---------------- 71
STLK6-RS        AV-ILS---HFFRHP-----NITTYWTVF---TV---------------- 71
OBSCN           RD-ILA---A-LSHP-----LVTGLLDQF---ET---------------- 66
SPEG            AR-LLA---R-LQHD-----CVLYFHEAF---ER---------------- 66
TRAD            AA-LLQ---H-LQHP-----QYITLHDTY---ES---------------- 66
TRIO            LG-ILQ---S-LQHP-----LLVGLLDTF---ET---------------- 66
SGK223          ------------THP---------------PAQE---------------- 67
SGK269          LA-VRQ---S-LAVH-----FNIKENQGVMSKKQ---------------- 70
ALK1            IY-NTVLL----RHD-----NILGFIASDMTS------------------ 65
ALK2            LY-NTVML----RHE-----NILGFIASDMTS------------------ 65
IRAK4           IK-VMAKC----QHE-----NLVELLGFSSDG------------------ 70
BMPR2           IY-RVPLM----EHD-----NIARFIVGDERV------------------ 65
TGFBR2          IF-SDINL----KHE-----NILQFLTAEERK------------------ 71
ACTR2           VY-SLPGM----KHE-----NILQFIGAEKRG------------------ 65
ACTR2B          IF-STPGM----KHE-----NLLQFIAAEKRG------------------ 65
1B6CB           IY-QTVML----RHE-----NILGFIAADNKD------------------ 65
TGFBR1          IY-QTVML----RHE-----NILGFIAADNKD------------------ 65
ALK4            IY-QTVML----RHE-----NILGFIAADNKD------------------ 65
ALK7            IY-QTVML----RHE-----NILGFIAADNKD------------------ 65
BMPR1A          IY-QTVLM----RHE-----NILGFIAADIKG------------------ 65
BMPR1B          IY-QTVLM----RHE-----NILGFIAADIKG------------------ 65
IRAK1           VE-QLSRF----RHP-----NIVDFAGYCAQN------------------ 70
IRAK2           LQ-I-CL---RCCHP-----NVLPVLGFCAARQFH--------------- 73
IRAK3           LE-V-LL---LFHHP-----NILELAAYFTETEKF--------------- 73
MISR2           LY-E-LP---GLQHD-----HIVRFITASRGGPGR--------------- 68
MYT1            VG-SHEK---VGQHP-----CCVRLEQAWEEGGIL--------------- 74
SBK             VS-ITNS---LSSSP-----FIIKVFDVVFETEDC--------------- 71
SGK110          FC-VGRC---VSAHP-----GLLQTLAGPLQTPRY--------------- 71
SGK069          FC-VGLS---LGAHS-----AIVTAYGIGIESAHS--------------- 71
SGK496          FH-YMRS---LPKHE-----RLVDLHGSVIDYNYG--------------- 72
NIK             EL-MACA---GLTSP-----RIVPLYGAVREGPWV--------------- 66
SGK424          -------------------------------------------------- 0
SURTK106        IQ-FHQY---LGKHK-----NLVQLEGCCTEKLPL--------------- 77
IKKE            FE-VLRKLN----HQ-----NIVKLFAVEETGGSR--------------- 72
TBK1            FE-VLKKLN----HK-----NIVKLFAIEEETTTR--------------- 72
MOS             EL-NVARLR----HD-----NIVRVVAASTRTPAG--------------- 71
LKB1            IQ-LLRRLR----HK-----NVIQLVDVLYNEEKQ--------------- 75
CAMKK1          IA-ILKKLD----HV-----NVVKLIEVLDDPAED--------------- 106
CAMKK2          IA-ILKKLD----HP-----NVVKLVEVLDDPNED--------------- 97
PASK            IA-ILSRVE----HA-----NIIKVLDIFENQGFF--------------- 79
PIM1            VV-LLKKVSS--GFS-----GVIRLLDWFERPDSF--------------- 79
PIM3            VV-LLRKVGAAGGAR-----GVIRLLDWFERPDGF--------------- 80
PIM2            VA-LLWKVGAGGGHP-----GVIRLLDWFETQEGF--------------- 81
COT             VE-IQACFR----HE-----NIAELYGAVLWGETV--------------- 68
SCYL2           VQ-QLTRLR----HP-----RLLTVQHPLEESRDC--------------- 83
FUSED           IE-IMRGL----RHP-----NIVHMLDS---------------------- 66
ULK1            IK-ILKEL----KHE-----NIVALYDF---------------------- 66
ULK2            IK-ILKEL----QHE-----NIVALYDV---------------------- 66
ULK3            IE-ILKGI----RHP-----HIVQLKDF---------------------- 67
ULK4            VR-LTREI----KHK-----NIVTFHEW---------------------- 61
IRE1            VQ-LLRES---DEHP-----NVIRYFCT---------------------- 61
IRE2            VQ-LLQES---DRHP-----NVLRYFCT---------------------- 61
RNASEL          VS-CLQSS---RENS-----HLVTFYGS---------------------- 55
MPSK1           AD-MHRLF----NHP-----NILRLVAYCLR------------------- 67
PINK1           RG-PKQLA----PHP-----NIIRVLRAFTSSVPLLP------------- 134
ALK             AL-IISKF----NHQ-----NIVRCIGVSLQ------------------- 73
LTK             AL-IISKF----RHQ-----NIVRCVGLSLR------------------- 73
ROS             AH-LMSKF----NHP-----NILKQLGVCLL------------------- 74
IGF1R           AS-VMKEF----NCH-----HVVRLLGVVSQ------------------- 73
1IR3A           AS-VMKGF----TCH-----HVVRLLGVVSK------------------- 73
INSR            AS-VMKGF----TCH-----HVVRLLGVVSK------------------- 73
IRR             AS-VMKAF----KCH-----HVVRLLGVVSQ------------------- 73
1M14A           AY-VMASV----DNP-----HVCRLLGICLT------------------- 72
EGFR            AY-VMASV----DNP-----HVCRLLGICLT------------------- 72
HER2/ERBB2      AY-VMAGV----GSP-----YVSRLLGICLT------------------- 72
HER4/ERBB4      AL-IMASM----DHP-----HLVRLLGVCLS------------------- 72
HER3/ERBB3      ML-AIGSL----DHA-----HIVRLLGLCPG------------------- 72
ITK             AE-VMMKL----SHP-----KLVQLYGVCLE------------------- 65
TEC             AK-VMMKL----THP-----KLVQLYGVCTQ------------------- 65
TXK             AK-VMMKL----SHS-----KLVQLYGVCIQ------------------- 65
BMX             AQ-TMMKL----SHP-----KLVKFYGVCSK------------------- 65
1K2PA           AK-VMMNL----SHE-----KLVQLYGVCTK------------------- 65
BTK             AK-VMMNL----SHE-----KLVQLYGVCTK------------------- 65
CCK4            LE-MFGKL----NHA-----NVVRLLGLCRE------------------- 72
ROR1            AS-LMAEL----HHP-----NIVCLLGAVTQ------------------- 72
ROR2            AM-LRARL----QHP-----NVVCLLGVVTK------------------- 73
MUSK            AA-LMAEF----DNP-----NIVKLLGVCAV------------------- 73
TRKA            AE-LLTML----QHQ-----HIVRFFGVCTE------------------- 72
TRKB            AE-LLTNL----QHE-----HIVKFYGVCVE------------------- 72
TRKC            AE-LLTNL----QHE-----HIVKFYGVCGD------------------- 72
DDR1            VK-IMSRL----KDP-----NIIRLLGVCVQ------------------- 84
DDR2            IK-IMSRL----KDP-----NIIHLLSVCIT------------------- 84
RYK             SC-KLRGL----HHR-----NLLPITHVCIE------------------- 73
JAK1            IE-ILRNL----YHE-----NIVKYKGICTED------------------ 72
JAK2            IE-ILKSL----QHD-----NIVKYKGVCYSA------------------ 72
JAK3            IQ-ILKAL----HSD-----FIVKYRGVSYGP------------------ 72
ACK             VN-AMHSL----DHR-----NLIRLYGVVLTP------------------ 74
TYK2            ID-ILRTL----YHE-----HIIKYKGCCEDQ------------------ 73
TNK1            VS-VMMNL----EHP-----HVLRLHGLVLGQ------------------ 75
EPHA1           AT-IMGQF----SHP-----HILHLEGVVTK------------------- 71
EPHA10          AL-TLGQF----DHS-----HIVRLEGVVTR------------------- 71
FAK             AL-TMRQF----DHP-----HIVKLIGVITE------------------- 71
EPHB6           AA-VLGQF----QHP-----NILRLEGVVTK------------------- 71
EPHA2           AG-IMGQF----SHH-----NIIRLEGVISK------------------- 72
EPHA8           AS-IMGQF----DHP-----NIIRLEGVVTR------------------- 71
EPHA6           AS-IMGQF----DHP-----NIIRLEGVVTKRSFPAI------------- 77
EPHB1           AS-IMGQF----DHP-----NIIRLEGVVTK------------------- 71
EPHB2           AS-IMGQF----DHP-----NVIHLEGVVTK------------------- 71
EPHB3           AS-IMGQF----DHP-----NIIRLEGVVTK------------------- 71
EPHB4           AS-IMGQF----EHP-----NIIRLEGVVTN------------------- 71
EPHA7           AS-IMGQF----DHP-----NVVHLEGVVTR------------------- 71
EPHA4           AS-IMGQF----DHP-----NIIHLEGVVTK------------------- 71
EPHA3           AS-IMGQF----DHP-----NIIRLEGVVTK------------------- 71
EPHA5           AS-IMGQF----DHP-----NIIHLEGVVTK------------------- 71
PYK2            AV-IMKNL----DHP-----HIVKLIGIIEE------------------- 71
CSK             AS-VMTQL----RHS-----NLVQLLGVIVE------------------- 63
CTK             TA-VMTKM----QHE-----NLVRLLGVILH------------------- 63
1IEPA           AA-VMKEI----KHP-----NLVQLLGVCTR------------------- 66
ABL             AA-VMKEI----KHP-----NLVQLLGVCTR------------------- 66
ARG             AA-VMKEI----KHP-----NLVQLLGVCTL------------------- 66
BRK             IQ-AMKKL----RHK-----HILALYAVVSVG------------------ 67
SRM             IQ-TLKGL----RHE-----RLIRLHAVCSGG------------------ 66
FRK             AQ-IMKNL----RHP-----KLIQLYAVCTLE------------------ 66
FGR             AQ-VMKLL----RHD-----KLVQLYAVVS-E------------------ 65
FYN             AQ-IMKKL----KHD-----KLVQLYAVVS-E------------------ 65
SRC             AQ-VMKKL----RHE-----KLVQLYAVVS-E------------------ 65
YES             AQ-IMKKL----RHD-----KLVPLYAVVS-E------------------ 65
HCK             AN-VMKTL----QHD-----KLVKLHAVVT-K------------------ 65
LYN             AN-LMKTL----QHD-----KLVRLYAVVTRE------------------ 66
3LCK            AN-LMKQL----QHQ-----RLVRLYAVVT-Q------------------ 65
LCK             AN-LMKQL----QHQ-----RLVRLYAVVT-Q------------------ 65
BLK             AN-VMKAL----QHE-----RLVRLYAVVT-K------------------ 65
FER             AK-ILKQY----DHP-----NIVKLIGVCTQR------------------ 68
FES             AR-ILKQY----SHP-----NIVRLIGVCTQK------------------ 69
SYK             AN-VMQQL----DNP-----YIVRMIGICEAE------------------ 72
ZAP70           AQ-IMHQL----DNP-----YIVRLIGVCQAE------------------ 71
FGFR1           ME-MMKMI---GKHK-----NIINLLGACTQ-DG---------------- 78
FGFR2           ME-MMKMI---GKHK-----NIINLLGACTQ-DG---------------- 78
FGFR3           ME-MMKMI---GKHK-----NIINLLGACTQ-GG---------------- 78
FGFR4           ME-VMKLI---GRHK-----NIINLLGVCTQ-EG---------------- 78
RET             FN-VLKQV---N-HP-----HVIKLYGACSQ-DG---------------- 75
TIE1            LE-VLCKL---GHHP-----NIINLLGACKN-RG---------------- 73
1FVRA           LE-VLCKL---GHHP-----NIINLLGACEH-RG---------------- 73
TIE2            LE-VLCKL---GHHP-----NIINLLGACEH-RG---------------- 73
FLT1            LK-ILTHI---GHHL-----NVVNLLGACTKQGG---------------- 77
KDR             LK-ILIHI---GHHL-----NVVNLLGACTKPGG---------------- 77
KDR_AVE         LK-ILIHI---GHHL-----NVVNLLGACTKPGG---------------- 77
FLT4            LK-ILIHI---GNHL-----NVVNLLGACTKPQG---------------- 77
FMS             LK-IMSHL---GQHE-----NIVNLLGACTH-GG---------------- 76
FLT3            LK-MMTQL---GSHE-----NIVNLLGACTL-SG---------------- 76
KIT             LK-VLSYL---GNHM-----NIVNLLGACTI-GG---------------- 76
PDGFRA          LK-IMTHL---GPHL-----NIVNLLGACTK-SG---------------- 76
PDGFRB          LK-IMSHL---GPHL-----NVVNLLGACTK-GG---------------- 76
MER             AA-CMKDF---S-HP-----NVIRLLGVCIEMSSQ--------------- 76
AXL             AV-CMKEF---D-HP-----NVMRLIGVCFQGSER--------------- 75
TYRO3           AA-CMKEF---D-HP-----HVAKLVGVSLRSRAK--------------- 76
MET             GI-IMKDF---S-HP-----NVLSLLGICLRSEG---------------- 74
RON             GL-LMRGL---N-HP-----NVLALIGIMLPPEG---------------- 74
HH498           VS-ILCQL----NHP-----CVIQFVGACLN------------------- 68
LZK             IK-HLRKL----KHP-----NIIAFKGVC--------------------- 56
DLK             IK-HLRKL----KHP-----NIITFKGVC--------------------- 56
MLK1            AK-LFAML----KHP-----NIIALRGVC--------------------- 67
MLK3            AR-LFAML----AHP-----NIIALKAVC--------------------- 67
MLK2            AR-LFGAL----QHP-----NIIALRGAC--------------------- 67
MLK4            AR-LFAML----RHP-----NIIELRGVC--------------------- 67
ZAK             AE-ILSVL----SHR-----NIIQFYGVI--------------------- 57
TAK1            LR-QLSRV----NHP-----NIVKLYGAC--------------------- 61
KSR1            VM-NYRQT----RHE-----NVVLFMGAC--------------------- 64
KSR2            VM-AYRQT----RHE-----NVVLFMGAC--------------------- 64
ARAF            MQ-VLRKT----RHV-----NILLFMGFMTR------------------- 66
RAF1            VA-VLRKT----RHV-----NILLFMGYMTK------------------- 66
BRAF            VG-VLRKT----RHV-----NILLFMGYS--------------------- 64
LRRK2           LV-VLCHL----HHP-----SLISLLAAG--------------------- 61
ANKRD3          AK-KMEMA----KFR-----YILPVYGIC--------------------- 67
SGK288          AA-KMKKI----KFQ-----HIVSIYGVC--------------------- 66
RIPK2           AE-ILHKA----RFS-----YILPILGIC--------------------- 68
RIPK3           VK-AMASL----DNE-----FVLRLEGVIEKVN----------------- 63
MLKL            IK-TMKKF----ESP-----NILRIFGICIDETVT--------------- 68
ANPA            LK-HMRDV----QNE-----HLTRFVGAC--------------------- 68
ANPB            LK-HMRDV----QFN-----HLTRFIGAC--------------------- 68
CYGD            FS-KLQEL----RHE-----NVALYLGLFLARGAE--------------- 73
CYGF            FE-MMKDL----RHE-----NINPLLGFF--------------------- 82
TBCK            FQ-ILKTI----THP-----RLCQYVDISRGK------------------ 46
ERK1            IQ-ILLRF-R---HE-----NVIGIRDILRAST----------------- 70
3ERK            IK-ILLRF-R---HE-----NIIGINDIIRAPT----------------- 70
ERK2            IK-ILLRF-R---HE-----NIIGINDIIRAPT----------------- 70
ERK5            LK-ILKHF-K---HD-----NIIAIKDILRPTVP---------------- 72
1JNK            LV-LMKCV-N---HK-----NIISLLNVFTPQKT---------------- 72
1PMNA           LV-LMKCV-N---HK-----NIISLLNVFTPQKT---------------- 72
JNK3            LV-LMKCV-N---HK-----NIISLLNVFTPQKT---------------- 72
JNK1            LV-LMKCV-N---HK-----NIIGLLNVFTPQKS---------------- 72
JNK2            LV-LLKCV-N---HK-----NIISLLNVFTPQKT---------------- 72
1P38            LR-LLKHM-K---HE-----NVIGLLDVFTPARS---------------- 72
P38A            LR-LLKHM-K---HE-----NVIGLLDVFTPARS---------------- 72
P38B            LR-LLKHL-K---HE-----NVIGLLDVFTPATS---------------- 72
P38D            LL-LLKHM-Q---HE-----NVIGLLDVFTPASS---------------- 72
P38G            LR-LLKHM-R---HE-----NVIGLLDVFTPDET---------------- 72
NLK             LK-MLCFF-K---HD-----NVLSALDILQPPH----------------- 71
ERK7            IT-LLQEFGD---HP-----NIISLLDVIRAE------------------ 90
ERK3            IK-IIRRL-D---HD-----NIVKVFEILGPSGSQLT------------- 73
ERK4            IK-IIRRL-D---HD-----NIVKVYEVLGPKGTD--------------- 71
ICK             VK-SLKKL-N---HA-----NVVKLKEVIREND----------------- 70
MAK             VK-SLKKL-N---HA-----NVIKLKEVIREND----------------- 70
PCTAIRE1        VS-LLKDL-K---HA-----NIVTLHDIIHTEK----------------- 70
PCTAIRE2        VS-LLKDL-K---HA-----NIVTLHDIVHTDK----------------- 70
PCTAIRE3        VS-LLKNL-K---HA-----NIVTLHDLIHTDR----------------- 70
PFTAIRE1        AS-LLKGL-K---HA-----NIVLLHDIIHTKE----------------- 70
PFTAIRE2        AS-LLKGL-K---HA-----NIVLLHDIIHTKE----------------- 70
CDC2            IS-LLKEL-R---HP-----NIVSLQDVLMQDS----------------- 71
1HCL            IS-LLKEL-N---HP-----NIVKLLDVIHTEN----------------- 67
CDK2            IS-LLKEL-N---HP-----NIVKLLDVIHTEN----------------- 71
CDK3            IS-LLKEL-K---HP-----NIVRLLDVVHNER----------------- 71
CDK5            IC-LLKEL-K---HK-----NIVRLHDVLHSDK----------------- 71
CDK7            IK-LLQEL-S---HP-----NIIGLLDAFGHKS----------------- 74
CDK4            VA-LLRRL-EAFEHP-----NVVRLMDVCATSRTD--------------- 79
1BLXA           VA-VLRHL-ETFEHP-----NVVRLFDVCTVSRTD--------------- 77
CDK6            VA-VLRHL-ETFEHP-----NVVRLFDVCTVSRTD--------------- 77
PITSLRE         IN-TILKA-Q---HP-----NIVTVREIVVGSN----------------- 71
CDK10           IT-LLLRL-R---HP-----NIVELKEVVVGNH----------------- 71
CDK9            IK-ILQLL-K---HE-----NVVNLIEICRTKASP--------------- 73
CHED            IK-ILRQL-T---HQ-----SIINMKEIVTDKEDA--------------- 73
CRK7            IK-ILRQL-I---HR-----SVVNMKEIVTDKQDA--------------- 73
CCRK            IK-ALQEM-E--DNQ-----YVVQLKAVFPHGG----------------- 72
CDK11           IA-LLREL-K---HP-----NVIALQKVFLSHSD---------------- 71
CDK8            IA-LLREL-K---HP-----NVISLQKVFLSHAD---------------- 71
IKKA            IQ-IMKKLN----HA-----NVVKACDVPE-------------------- 67
IKKB            IQ-IMRRLT----HP-----NVVAARDVPE-------------------- 67
1PHK            VD-ILRKVS---GHP-----NIIQLKDTYE-------------------- 76
PHKG1           VD-ILRKVS---GHP-----NIIQLKDTYE-------------------- 76
PHKG2           TH-ILRQVA---GHP-----HIITLIDSYE-------------------- 75
CAMK2A          AR-ICRLLK----HP-----NIVRLHDSIS-------------------- 68
CAMK2B          AR-ICRLLK----HS-----NIVRLHDSIS-------------------- 68
CAMK2G          AR-ICRLLK----HP-----NIVRLHDSIS-------------------- 68
CAMK2D          AR-ICRLLK----HP-----NIVRLHDSIS-------------------- 68
CASK            AS-ICHMLK----HP-----HIVELLETYS-------------------- 71
1IA8A           IC-INKMLN----HE-----NVVKFYGHRR-------------------- 64
CHK1            IC-INKMLN----HE-----NVVKFYGHRR-------------------- 67
CLK1            IQ-VLEHLN---TTDPNSTFRCVQMLEWFE-------------------- 72
CLK4            IQ-VLEHLN---STDPNSVFRCVQMLEWFD-------------------- 71
CLK2            IN-VLEKIN---EKDPDNKNLCVQMFDWFD-------------------- 72
CLK3            IN-VLKKIK---EKDKENKFLCVLMSDWFN-------------------- 72
MAP2K5          LEI-L----YKCDSS-----YIIGFYGAFF-------------------- 67
MAP2K3          LDINM----RTVDCF-----YTVTFYGALF-------------------- 68
MAP2K6          LDISM----RTVDCP-----FTVTFYGALF-------------------- 68
MAP2K4          LDVVM----RSSDCP-----YIVQFYGALF-------------------- 68
MAP2K7          LDVVL----KSHDCP-----YIVQCFGTFI-------------------- 68
MAP2K1          LQV-L----HECNSP-----YIVGFYGAFY-------------------- 67
MAP2K2          LQV-L----HECNSP-----YIVGFYGAFY-------------------- 67
CDKL5           LK-MLRTL----KQE-----NIVELKEAFR-------------------- 68
CDKL1           IR-MLKQL----KHP-----NLVNLLEVFR-------------------- 68
CDKL4           IR-MLKQL----KHP-----NLVNLIEVFR-------------------- 68
CDKL2           IK-LLKQL----RHE-----NLVNLLEVCK-------------------- 68
CDKL3           IK-FLKQF----HHE-----NLVNLIEVFR-------------------- 67
1I09B           LQ-IMRKL----DHC-----NIVRLRYFFYSSGEK--------------- 67
GSK3B           LQ-IMRKL----DHC-----NIVRLRYFFYSSGEK--------------- 67
1J1BA           LQ-IMRKL----DHC-----NIVRLRYFFYSSGEK--------------- 67
GSK3A           LQ-IMRKL----DHC-----NIVRLRYFFYSSGEK--------------- 67
LATS1           RD-ILAEA----DNE-----WVVRLYYSF--------------------- 68
LATS2           RD-ILAEA----DNE-----WVVKLYYSF--------------------- 68
NDR1            RD-ILVEA----DSL-----WVVKMFYSF--------------------- 68
NDR2            RD-ILVEA----DGA-----WVVKMFYSF--------------------- 68
MAST1           RD-ILTFA----ENP-----FVVGMFCSF--------------------- 68
MAST4           RD-ILTFA----ENP-----FVVSMYCSF--------------------- 68
MAST2           RD-ILTFA----ENP-----FVVSMFCSF--------------------- 68
MAST3           RD-ILTFA----ENP-----FVVSMFCSF--------------------- 68
MRCKA           RD-VLVNG----DNK-----WITTLHYAF--------------------- 68
MRCKB           RD-VLVNG----DCQ-----WITALHYAF--------------------- 68
DMPK2           RD-VLVKG----DSR-----WVTTLHYAF--------------------- 68
DMPK1           RD-VLVNG----DRR-----WITQLHFAF--------------------- 68
ROCK1           RD-IMAFA----NSP-----WVVQLFYAF--------------------- 68
ROCK2           RD-IMAFA----NSP-----WVVQLFYAF--------------------- 68
CRIK            RN-ILSRS----TSP-----WIPQLQYAF--------------------- 68
MASTL           RD-ALALS----KSP-----FIVHLYYSL--------------------- 66
1O6LA           SR-VL-QNT---RHP-----FLTALKYAF--------------------- 68
AKT2            SR-VL-QNT---RHP-----FLTALKYAF--------------------- 68
AKT1            NR-VL-QNS---RHP-----FLTALKYSF--------------------- 68
AKT3            SR-VL-KNT---RHP-----FLTSLKYSF--------------------- 68
MSK1            RQ-VL-EHIR--QSP-----FLVTLHYAF--------------------- 73
MSK2            RS-VL-ELVR--QAP-----FLVTLHYAF--------------------- 73
P70S6K          RN-IL-EEVK---HP-----FIVDLIYAF--------------------- 72
P70S6KB         RN-IL-ESVK---HP-----FIVELAYAF--------------------- 72
RSK1            RD-IL-AEVN---HP-----FIVKLHYAF--------------------- 70
RSK3            RD-IL-ADVN---HP-----FVVKLHYAF--------------------- 70
RSK2            RD-IL-VEVN---HP-----FIVKLHYAF--------------------- 70
RSK4            RD-IL-VEVN---HP-----FIVKLHYAF--------------------- 70
1FOTA           RL-ML-SIVT---HP-----FIIRMWGTF--------------------- 68
1CDKA           KR-IL-QAVN---FP-----FLVKLEYSF--------------------- 68
PKACA           KR-IL-QAVN---FP-----FLVKLEFSF--------------------- 68
PKACB           KR-IL-QAVN---FP-----FLVRLEYAF--------------------- 68
PKACG           KR-IL-QAID---FP-----FLVKLQFSF--------------------- 68
PRKX            KS-VL-KEVS---HP-----FLIRLFWTW--------------------- 68
PRKY            KS-VL-KEVS---HP-----FLIRLFWTW--------------------- 68
PKCA            KR-VL-ALLD--KPP-----FLTQLHSCF--------------------- 69
PKCB            KR-VL-ALPG--KPP-----FLTQLHSCF--------------------- 69
PKCG            KR-VL-ALGG--RGPGGRPHFLTQLHSTF--------------------- 74
PKCE            KR-IL-ALAR--KHP-----YLTQLYCCF--------------------- 69
PKCH            KR-IL-SLAR--NHP-----FLTQLFCCF--------------------- 69
PKCD            KR-VL-TLAA--ENP-----FLTHLICTF--------------------- 69
PKCT            KR-VL-SLAW--EHP-----FLTHMFCTF--------------------- 69
PKCI            KH-VF-EQAS--NHP-----FLVGLHSCF--------------------- 69
PKCZ            KH-VF-EQAS--SNP-----FLVGLHSCF--------------------- 69
PKN1            KR-IL-AAVTSAGHP-----FLVNLFGCF--------------------- 71
PKN2            KR-IF-ETVNSVRHP-----FLVNLFACF--------------------- 71
PKN3            KR-IL-EAVGCTGHP-----FLLSLLVCF--------------------- 71
SGK             RN-VLLKNV---KHP-----FLVGLHFSF--------------------- 69
SGK2            RS-VLLKNV---RHP-----FLVGLRYSF--------------------- 69
SGK3            RN-VLLKNV---KHP-----FLVGLHYSF--------------------- 69
PKG1            KQ-IM-QGAH---SD-----FIVRLYRTF--------------------- 69
PKG2            KR-IL-EELC---SP-----FIVKLYRTF--------------------- 68
AURB            IE-IQAHL----HHP-----NILRLYNYFY-------------------- 69
AURC            IE-IQAHL----QHP-----NILRLYNYFH-------------------- 69
AURA            VE-IQSHL----RHP-----NILRLYGYFH-------------------- 69
AURORA2_AVE     VE-IQSHL----RHP-----NILRLYGYFH-------------------- 69
PLK1            IS-IHRSL----AHQ-----HVVGFHGFFE-------------------- 69
PLK2            IE-LHRIL----HHK-----HVVQFYHYFE-------------------- 69
PLK3            IE-LHRDL----QHR-----HIVRFSHHFE-------------------- 69
PLK4            VK-IHCQL----KHP-----SILELYNYFE-------------------- 69
NEK11           AQ-LLSKL----DHP-----AIVKFHASFV-------------------- 71
YANK1           LQ-IMQGL----EHP-----FLVNLWYSF--------------------- 68
YANK2           LQ-IMQGL----EHP-----FLVNLWYSF--------------------- 68
YANK3           LE-ILQEI----EHV-----FLVNLWYSF--------------------- 68
SGK494          VS-IQRQI----NHP-----FVHSLGDSW--------------------- 68
DOMAIN2_MSK1    ITALKL---CEG-HP-----NIVKLHEVFHDQ------------------ 66
DOMAIN2_MSK2    VAALRL---CQS-HP-----NVVNLHEVHHDQ------------------ 60
DOMAIN2_RSK1    IEILLR---YGQ-HP-----NIITLKDVYDDG------------------ 65
DOMAIN2_RSK2    IEILLR---YGQ-HP-----NIITLKDVYDDG------------------ 65
DOMAIN2_RSK3    IEILLR---YGQ-HP-----NIITLKDVYDDG------------------ 65
DOMAIN2_RSK4    IEILMR---YGQ-HP-----NIITLKDVFDDG------------------ 65
DRAK1           IA-VLE---LAQDNP-----WVINLHEVYETA------------------ 71
DRAK2           IA-VLE---LAKSCP-----RVINLHEVYENT------------------ 71
1JKSA           VS-ILK---EIQ-HP-----NVITLHEVYENK------------------ 74
DAPK1           VS-ILK---EIQ-HP-----NVITLHEVYENK------------------ 74
DAPK3           VN-ILR---EIR-HP-----NIITLHDIFENK------------------ 74
DAPK2           VS-ILR---QVL-HH-----NVITLHDVYENR------------------ 74
SGK085          IS-VMN---QLD-HA-----NLIQLYDAFESK------------------ 68
CAMLCK          IN-IMN---QLS-HV-----NLIQLYDAFESK------------------ 68
SKMLCK          IE-VMN---QLN-HR-----NLIQLYAAIETP------------------ 68
SMMLCK          IS-IMN---CLH-HP-----KLVQCVDAFEEK------------------ 68
1KOBA           IS-IMN---QLH-HP-----KLINLHDAFEDK------------------ 68
1TKIA           IS-ILN---IAR-HR-----NILHLHESFESM------------------ 67
TTN             IS-ILN---IAR-HR-----NILHLHESFESM------------------ 67
PKD1            VA-ILQ---NLH-HP-----GVVNLECMFETP------------------ 70
PKD3            VA-ILQ---NLH-HP-----GIVNLECMFETP------------------ 70
PKD2            VA-ILQ---SLR-HP-----GIVNLECMFETP------------------ 70
PSKH1           LR-VLR---RVR-HA-----NIIQLVEVFETQ------------------ 68
PSKH2           LS-VLR---RVS-HR-----YIVQLMEIFETE------------------ 68
CAMK1A          IA-VLH---KIK-HP-----NIVALDDIYESG------------------ 69
CAMK1D          IA-VLR---KIK-HE-----NIVALEDIYESP------------------ 69
CAMK1B          IA-VLR---RIS-HP-----NIVALEDVHESP------------------ 69
CAMK1G          IA-VLK---KIK-HE-----NIVTLEDIYEST------------------ 68
CAMK4           IG-VLL---RLS-HP-----NIIKLKEIFETP------------------ 66
DCAMKL1         VS-ILR---RVK-HP-----NIVLLIEEMDVP------------------ 69
DCAMKL2         VS-ILR---RVK-HP-----NIIMLVEEMETA------------------ 69
DCAMKL3         IL-IIQ---SLS-HP-----NIVKLHEVYETD------------------ 69
CHK2            IE-ILK---KLN-HP-----CIIKIKNFFDAE------------------ 76
MAPKAPK2        VELHWR---ASQ-CP-----HIVRIVDVYENLY----------------- 65
MAPKAPK3        VDHHWQ---ASG-GP-----HIVCILDVYENMH----------------- 65
MAPKAPK5        VRLHMM---CAT-HP-----NIVQIIEVFANSV----------------- 65
MNK1            VETLYQ---CQG-NK-----NILELIEFFEDD------------------ 70
MNK2            VEMLYQ---CQG-HR-----NVLELIEFFEEE------------------ 69
VACAMKL         IG-ILK---MVK-HP-----NILQLVDVFVTR------------------ 69
GCK             IT-ILREC----RHP-----NVVAYIGSYL-------------------- 66
KHS1            IF-MVKEC----KHC-----NIVAYFGSYL-------------------- 66
KHS2            II-MMKDC----KHP-----NIVAYFGSYL-------------------- 66
HPK1            IL-ILKTC----RHA-----NIVAYHGSYL-------------------- 66
MST1            IS-IMQQC----DSP-----HVVKYYGSYF-------------------- 64
MST2            IS-IMQQC----DSP-----YVVKYYGSYF-------------------- 64
MST3            IT-VLSQC----DSP-----YVTKYYGSYL-------------------- 67
YSK1            IT-VLSQC----DSP-----YITRYFGSYL-------------------- 67
MST4            IT-VLSQC----DSS-----YVTKYYGSYL-------------------- 67
LOK             IE-ILATC----DHP-----YIVKLLGAYY-------------------- 66
SLK             ID-ILASC----DHP-----NIVKLLDAFY-------------------- 66
MAP3K4          LK-IFEGI----KHP-----NLVRYFGVEL-------------------- 68
MAP3K2          IQ-LLKNF----LHE-----RIVQYYGCLR-------------------- 71
MAP3K3          IQ-LLKNL----QHE-----RIVQYYGCLR-------------------- 71
MAP3K8          VD-LLKAL----KHV-----NIVAYLGTCL-------------------- 71
MAP3K5          IA-LHKHL----KHK-----NIVQYLGSFS-------------------- 71
MAP3K7          IA-LHKYL----KHR-----NIVQYLGSVS-------------------- 64
MAP3K6          IA-LHRRL----RHK-----NIVRYLGSAS-------------------- 61
PAK1            IL-VMREN----KNP-----NIVNYLDSYL-------------------- 66
PAK3            IL-VMREN----KNP-----NIVNYLDSYL-------------------- 66
PAK2            IL-VMKEL----KNP-----NIVNFLDSYL-------------------- 66
PAK4            VV-IMRDY----QHE-----NVVEMYNSYL-------------------- 66
PAK5            VV-IMRDY----HHD-----NVVDMYSSYL-------------------- 66
PAK6            VV-IMRDY----QHF-----NVVEMYKSYL-------------------- 66
OSR1            IQ-AMSQC----HHP-----NIVSYYTSFV-------------------- 67
STLK3           IQ-AMSQC----SHP-----NVVTYYTSFV-------------------- 67
TAO1            VK-FLQRI----KHP-----NSIEYKGCYL-------------------- 69
TAO3            VK-FLRQL----KHP-----NTIEYKGCYL-------------------- 69
TAO2            VR-FLQKL----RHP-----NTIQYRGCYL-------------------- 69
MYO3A           YN-ILKAL---SDHP-----NVVRFYGIYF-------------------- 66
MYO3B           YN-ILQFL---PNHP-----NVVKFYGMFY-------------------- 66
ZC1/HGK         IN-MLKKY---SHHR-----NIATYYGAFI-------------------- 66
ZC3/MINK        IN-MLKKY---SHHR-----NIATYYGAFI-------------------- 66
ZC2/TNIK        IN-MLKKY---SHHR-----NIATYYGAFI-------------------- 66
ZC4/NRK         LN-LLRKY---SFHK-----NIVSFYGAFF-------------------- 90
MAP3K1          IR-MMSHL----NHP-----NIIRMLGATC-------------------- 72
GAK             VC-FMKKL---SGHP-----NIVQFCSAASIGKEES-------------- 73
SGK495          -------------------------------------------------- 0
TRB1            RP-YIQLP---S-HS-----NITGIVEV-------I-------------- 52
TRB2            AP-CFCLS----AHS-----NINQITEI-------I-------------- 57
TRB3            EP-YARLP----PHK-----HVARPTEV-------L-------------- 55
SSTK            LS-ILRGV---R-HP-----HIVHVFEF-------I-------------- 68
TSSK3           LQ-IVRTL---D-HK-----NIIQVYEM-------L-------------- 68
TSSK1           IE-ILAML---N-HC-----SIIKTYEI-------F-------------- 68
TSSK2           MD-ILATV---N-HG-----SIIKTYEI-------F-------------- 68
TSSK4           IQ-VMKVL---R-HK-----YLINFYRA-------I-------------- 68
HUNK            GQ-IQQMI---R-HP-----NITQLLDI-------L-------------- 70
SNRK            VR-CMKLV---Q-HP-----NIVRLYEV-------I-------------- 67
NIM1            IS-SMEKL---H-HP-----NIIRLYEV-------V-------------- 67
MELK            IE-ALKNL---R-HQ-----HICQLYHV-------L-------------- 66
BRSK1           IA-ILKLI---E-HP-----HVLKLHDV-------Y-------------- 67
BRSK2           IA-ILKLI---E-HP-----HVLKLHDV-------Y-------------- 67
MARK1           VR-IMKIL---N-HP-----NIVKLFEV-------I-------------- 67
MARK2           VR-IMKVL---N-HP-----NIVKLFEV-------I-------------- 67
MARK3           VR-IMKIL---N-HP-----NIVKLFEV-------I-------------- 67
MARK4           VR-IMKGL---N-HP-----NIVKLFEV-------I-------------- 67
QIK             VQ-IMKML---D-HP-----HIIKLYQV-------M-------------- 67
SIK             VQ-LMKLL---N-HP-----HIIKLYQV-------M-------------- 67
QSK             VQ-IMKML---C-HP-----HIIRLYQV-------M-------------- 67
AMPKA1          IQ-NLKLF---R-HP-----HIIKLYQV-------I-------------- 68
AMPKA2          IQ-NLKLF---R-HP-----HIIKLYQV-------I-------------- 68
NUAK1           IE-IMSSL---N-HP-----HIISIYEV-------F-------------- 68
NUAK2           IE-IMSSL---N-HP-----HIIAIHEV-------F-------------- 67
BIKE            IT-IMKEL---SGHK-----NIVGYLDCAVNS--IS-------------- 70
AAK1            IQ-IMRDL---SGHK-----NIVGYIDSSINN--VS-------------- 70
LIMK1           VK-VMR----CLEHP-----NVLKFIGVLYK------------------- 67
LIMK2           VK-VMR----SLDHP-----NVLKFIGVLYK------------------- 67
TESK1           VQ-LMN----RLRHP-----NILRFMGVCVH------------------- 65
TESK2           VQ-LMN----RLSHP-----NILRY------------------------- 55
WNK1            AE-MLK----GLQHP-----NIVRFYDSWESTV----------------- 71
WNK3            AE-MLK----GLQHP-----NIVRFYDSWESIL----------------- 71
WNK2            AE-MLK----GLQHP-----NIVRFYDFWESSA----------------- 71
WNK4            VE-MLK----GLQHP-----NIVRFYDSWKSVL----------------- 71
NEK10           LT-IIK---EQLYHP-----NIVRYYKTFLE------------------- 78
NEK6            IG-LLK----QLNHP-----NIIKYLDSFIE------------------- 70
NEK7            ID-LLK----QLNHP-----NVIKYYASFIE------------------- 70
NEK2            VN-LLR----ELKHP-----NIVRYYDRIID------------------- 69
NEK1            VA-VLA----NMKHP-----NIVQYRESFEE------------------- 69
NEK5            VI-LLE----KMKHP-----NIVAFFNSFQE------------------- 69
NEK3            AV-LLA----KMKHP-----NIVAFKESFEA------------------- 68
NEK4            AQ-LLS----QLKHP-----NIVTYKESWEG------------------- 69
NEK8            CQ-VLK----LLNHP-----NVIEYYENFLE------------------- 69
NEK9            IV-ILA----LLQHD-----NIIAYYNHFMD------------------- 69
NRBP1           FD-NLI----QLEHL-----NIVKFHKYWADIK----------------- 76
NRBP2           FE-QLV----LVDHP-----NIVKLHKYWLDTS----------------- 76
CLIK1           FW-ALTSLK--RRHQ-----NVVQFEECVLQRNGLA-------------- 74
CLIK1L          FW-ALSSIK--SQHP-----NVIHLEECILQKDGMV-------------- 74
STK33           VN-ILKSVK--HEH-------IIHLEQVF--------------------- 67
DOMAIN2_GCN2    FN-SLVKL----SHP-----N----------------------------- 78
SCYL1           FK-RFKTL----RHP-----N----------------------------- 47
SCYL3           AK-HLKTL----RHP-----C----------------------------- 40
DOMAIN2_JAK1    AS-MMRQV----SHK-----H----------------------------- 67
DOMAIN2_TYK2    AS-LMSQV----SHT-----H----------------------------- 81
DOMAIN2_JAK2    AS-MMSKL----SHK-----H----------------------------- 64
DOMAIN2_JAK3    AS-LMSQV----SYR-----H----------------------------- 63
ILK             CP-RLRIF----SHP-----N----------------------------- 57
LRRK1           AS-MLHAL----QHP-----C----------------------------- 77
PBK             AK-ILKSL----HHP-----N----------------------------- 65
WEE1            YA-HAVLG----QHS-----H----------------------------- 60
WEE1B           YA-HAVLG----HHP-----H----------------------------- 60
SGK071          LM-PLLKL----RHA-----H----------------------------- 57
PIK3R4          -------------------------------------------------- 50
MSSK1           IK-LLKCV----RDS-----D---PSDPKRETIVQLIDD----------- 71
SRPK1           IR-LLKSV----RNS-----D---PNDPNREMVVQLLDD----------- 71
SRPK2           IK-LLKCV----RES-----D---PSDPNKDMVVQLIDD----------- 71
RSKL1           ------------------------LAKEEPTSLFQRDSE----------- 46
RSKL2           RI-ALEPP----RTS-----PNLLLAGEAPSTRPQREAEGEPTARTS--- 159
SGK396          -------------------------------------------------- 51
VRK1            -------L----KYL-----G----------------------------- 73
VRK2            -------L----DYL-----G----------------------------- 71
VRK3            PT-CMGFG----VHQ-----D----------------------------- 32
BUB1            -------------------------------------------------- 62
BUBR1           -------------------------------------------------- 69
SGK196          LQ-MLKSL----QGT-----H----------------------------- 53
SGK493          MV-LLERL----RHP-----N----------------------------- 70
                                                                  

DYRK1A          -------------------------------------------------- 66
DYRK1B          -------------------------------------------------- 66
DYRK2           -------------------------------------------------- 66
DYRK3           -------------------------------------------------- 66
DYRK4           -------------------------------------------------- 66
HIPK1           -------------------------------------------------- 65
HIPK2           -------------------------------------------------- 65
HIPK3           -------------------------------------------------- 65
HIPK4           -------------------------------------------------- 65
PRP4            -------------------------------------------------- 67
MOK             -------------------------------------------------- 63
1A6O            -------------------------------------------------- 59
1LPUA           -------------------------------------------------- 59
CK2A1           -------------------------------------------------- 59
CK2A1-RS        -------------------------------------------------- 59
CK2A2           -------------------------------------------------- 59
HSER            -------------------------------------------------- 51
SLOB            -------------------------------------------------- 64
CDC7            -------------------------------------------------- 63
1CSN            -------------------------------------------------- 60
CK1G1           -------------------------------------------------- 61
CK1G3           -------------------------------------------------- 60
CK1G2           -------------------------------------------------- 60
CK1A            -------------------------------------------------- 60
CK1A2           -------------------------------------------------- 60
1CKJA           -------------------------------------------------- 60
CK1D            -------------------------------------------------- 60
CK1E            -------------------------------------------------- 60
TTBK1           -------------------------------------------------- 60
TTBK2           -------------------------------------------------- 60
TLK1            -------------------------------------------------- 68
TLK2            -------------------------------------------------- 68
GPRK4           -------------------------------------------------- 64
GPRK6           -------------------------------------------------- 64
GPRK5           -------------------------------------------------- 64
RHOK            -------------------------------------------------- 64
GPRK7           -------------------------------------------------- 64
BARK1           -------------------------------------------------- 67
BARK2           -------------------------------------------------- 67
TTK             -------------------------------------------------- 64
RIPK1           -------------------------------------------------- 62
HASPIN          -------------------------------------------------- 69
GCN2            TPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGE 127
HRI             LPSLEVLSDQEEDREQCGVKNDESSSSSIIFAEPTPEKEKRFGESDTENQ 134
KIS             -------------------------------------------------- 87
PDK1            -------------------------------------------------- 68
PKR             -------------------------------------------------- 65
PEK             TDWPLSSPSPMDAPSVKIRRMDPFSTKEHIEIIAPSPQRSRSFSVGISCD 137
PRPK            -------------------------------------------------- 73
DOMAIN2_OBSCN   -------------------------------------------------- 66
DOMAIN2_SPEG    -------------------------------------------------- 66
LMR1            -------------------------------------------------- 70
LMR2            -------------------------------------------------- 70
LMR3            -------------------------------------------------- 70
SGK307          -------------------------------------------------- 6
STLK5           -------------------------------------------------- 71
STLK6           -------------------------------------------------- 71
STLK6-RS        -------------------------------------------------- 71
OBSCN           -------------------------------------------------- 66
SPEG            -------------------------------------------------- 66
TRAD            -------------------------------------------------- 66
TRIO            -------------------------------------------------- 66
SGK223          -------------------------------------------------- 67
SGK269          -------------------------------------------------- 70
ALK1            -------------------------------------------------- 65
ALK2            -------------------------------------------------- 65
IRAK4           -------------------------------------------------- 70
BMPR2           -------------------------------------------------- 65
TGFBR2          -------------------------------------------------- 71
ACTR2           -------------------------------------------------- 65
ACTR2B          -------------------------------------------------- 65
1B6CB           -------------------------------------------------- 65
TGFBR1          -------------------------------------------------- 65
ALK4            -------------------------------------------------- 65
ALK7            -------------------------------------------------- 65
BMPR1A          -------------------------------------------------- 65
BMPR1B          -------------------------------------------------- 65
IRAK1           -------------------------------------------------- 70
IRAK2           -------------------------------------------------- 73
IRAK3           -------------------------------------------------- 73
MISR2           -------------------------------------------------- 68
MYT1            -------------------------------------------------- 74
SBK             -------------------------------------------------- 71
SGK110          -------------------------------------------------- 71
SGK069          -------------------------------------------------- 71
SGK496          -------------------------------------------------- 72
NIK             -------------------------------------------------- 66
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 77
IKKE            -------------------------------------------------- 72
TBK1            -------------------------------------------------- 72
MOS             -------------------------------------------------- 71
LKB1            -------------------------------------------------- 75
CAMKK1          -------------------------------------------------- 106
CAMKK2          -------------------------------------------------- 97
PASK            -------------------------------------------------- 79
PIM1            -------------------------------------------------- 79
PIM3            -------------------------------------------------- 80
PIM2            -------------------------------------------------- 81
COT             -------------------------------------------------- 68
SCYL2           -------------------------------------------------- 83
FUSED           -------------------------------------------------- 66
ULK1            -------------------------------------------------- 66
ULK2            -------------------------------------------------- 66
ULK3            -------------------------------------------------- 67
ULK4            -------------------------------------------------- 61
IRE1            -------------------------------------------------- 61
IRE2            -------------------------------------------------- 61
RNASEL          -------------------------------------------------- 55
MPSK1           -------------------------------------------------- 67
PINK1           -------------------------------------------------- 134
ALK             -------------------------------------------------- 73
LTK             -------------------------------------------------- 73
ROS             -------------------------------------------------- 74
IGF1R           -------------------------------------------------- 73
1IR3A           -------------------------------------------------- 73
INSR            -------------------------------------------------- 73
IRR             -------------------------------------------------- 73
1M14A           -------------------------------------------------- 72
EGFR            -------------------------------------------------- 72
HER2/ERBB2      -------------------------------------------------- 72
HER4/ERBB4      -------------------------------------------------- 72
HER3/ERBB3      -------------------------------------------------- 72
ITK             -------------------------------------------------- 65
TEC             -------------------------------------------------- 65
TXK             -------------------------------------------------- 65
BMX             -------------------------------------------------- 65
1K2PA           -------------------------------------------------- 65
BTK             -------------------------------------------------- 65
CCK4            -------------------------------------------------- 72
ROR1            -------------------------------------------------- 72
ROR2            -------------------------------------------------- 73
MUSK            -------------------------------------------------- 73
TRKA            -------------------------------------------------- 72
TRKB            -------------------------------------------------- 72
TRKC            -------------------------------------------------- 72
DDR1            -------------------------------------------------- 84
DDR2            -------------------------------------------------- 84
RYK             -------------------------------------------------- 73
JAK1            -------------------------------------------------- 72
JAK2            -------------------------------------------------- 72
JAK3            -------------------------------------------------- 72
ACK             -------------------------------------------------- 74
TYK2            -------------------------------------------------- 73
TNK1            -------------------------------------------------- 75
EPHA1           -------------------------------------------------- 71
EPHA10          -------------------------------------------------- 71
FAK             -------------------------------------------------- 71
EPHB6           -------------------------------------------------- 71
EPHA2           -------------------------------------------------- 72
EPHA8           -------------------------------------------------- 71
EPHA6           -------------------------------------------------- 77
EPHB1           -------------------------------------------------- 71
EPHB2           -------------------------------------------------- 71
EPHB3           -------------------------------------------------- 71
EPHB4           -------------------------------------------------- 71
EPHA7           -------------------------------------------------- 71
EPHA4           -------------------------------------------------- 71
EPHA3           -------------------------------------------------- 71
EPHA5           -------------------------------------------------- 71
PYK2            -------------------------------------------------- 71
CSK             -------------------------------------------------- 63
CTK             -------------------------------------------------- 63
1IEPA           -------------------------------------------------- 66
ABL             -------------------------------------------------- 66
ARG             -------------------------------------------------- 66
BRK             -------------------------------------------------- 67
SRM             -------------------------------------------------- 66
FRK             -------------------------------------------------- 66
FGR             -------------------------------------------------- 65
FYN             -------------------------------------------------- 65
SRC             -------------------------------------------------- 65
YES             -------------------------------------------------- 65
HCK             -------------------------------------------------- 65
LYN             -------------------------------------------------- 66
3LCK            -------------------------------------------------- 65
LCK             -------------------------------------------------- 65
BLK             -------------------------------------------------- 65
FER             -------------------------------------------------- 68
FES             -------------------------------------------------- 69
SYK             -------------------------------------------------- 72
ZAP70           -------------------------------------------------- 71
FGFR1           -------------------------------------------------- 78
FGFR2           -------------------------------------------------- 78
FGFR3           -------------------------------------------------- 78
FGFR4           -------------------------------------------------- 78
RET             -------------------------------------------------- 75
TIE1            -------------------------------------------------- 73
1FVRA           -------------------------------------------------- 73
TIE2            -------------------------------------------------- 73
FLT1            -------------------------------------------------- 77
KDR             -------------------------------------------------- 77
KDR_AVE         -------------------------------------------------- 77
FLT4            -------------------------------------------------- 77
FMS             -------------------------------------------------- 76
FLT3            -------------------------------------------------- 76
KIT             -------------------------------------------------- 76
PDGFRA          -------------------------------------------------- 76
PDGFRB          -------------------------------------------------- 76
MER             -------------------------------------------------- 76
AXL             -------------------------------------------------- 75
TYRO3           -------------------------------------------------- 76
MET             -------------------------------------------------- 74
RON             -------------------------------------------------- 74
HH498           -------------------------------------------------- 68
LZK             -------------------------------------------------- 56
DLK             -------------------------------------------------- 56
MLK1            -------------------------------------------------- 67
MLK3            -------------------------------------------------- 67
MLK2            -------------------------------------------------- 67
MLK4            -------------------------------------------------- 67
ZAK             -------------------------------------------------- 57
TAK1            -------------------------------------------------- 61
KSR1            -------------------------------------------------- 64
KSR2            -------------------------------------------------- 64
ARAF            -------------------------------------------------- 66
RAF1            -------------------------------------------------- 66
BRAF            -------------------------------------------------- 64
LRRK2           -------------------------------------------------- 61
ANKRD3          -------------------------------------------------- 67
SGK288          -------------------------------------------------- 66
RIPK2           -------------------------------------------------- 68
RIPK3           -------------------------------------------------- 63
MLKL            -------------------------------------------------- 68
ANPA            -------------------------------------------------- 68
ANPB            -------------------------------------------------- 68
CYGD            -------------------------------------------------- 73
CYGF            -------------------------------------------------- 82
TBCK            -------------------------------------------------- 46
ERK1            -------------------------------------------------- 70
3ERK            -------------------------------------------------- 70
ERK2            -------------------------------------------------- 70
ERK5            -------------------------------------------------- 72
1JNK            -------------------------------------------------- 72
1PMNA           -------------------------------------------------- 72
JNK3            -------------------------------------------------- 72
JNK1            -------------------------------------------------- 72
JNK2            -------------------------------------------------- 72
1P38            -------------------------------------------------- 72
P38A            -------------------------------------------------- 72
P38B            -------------------------------------------------- 72
P38D            -------------------------------------------------- 72
P38G            -------------------------------------------------- 72
NLK             -------------------------------------------------- 71
ERK7            -------------------------------------------------- 90
ERK3            -------------------------------------------------- 73
ERK4            -------------------------------------------------- 71
ICK             -------------------------------------------------- 70
MAK             -------------------------------------------------- 70
PCTAIRE1        -------------------------------------------------- 70
PCTAIRE2        -------------------------------------------------- 70
PCTAIRE3        -------------------------------------------------- 70
PFTAIRE1        -------------------------------------------------- 70
PFTAIRE2        -------------------------------------------------- 70
CDC2            -------------------------------------------------- 71
1HCL            -------------------------------------------------- 67
CDK2            -------------------------------------------------- 71
CDK3            -------------------------------------------------- 71
CDK5            -------------------------------------------------- 71
CDK7            -------------------------------------------------- 74
CDK4            -------------------------------------------------- 79
1BLXA           -------------------------------------------------- 77
CDK6            -------------------------------------------------- 77
PITSLRE         -------------------------------------------------- 71
CDK10           -------------------------------------------------- 71
CDK9            -------------------------------------------------- 73
CHED            -------------------------------------------------- 73
CRK7            -------------------------------------------------- 73
CCRK            -------------------------------------------------- 72
CDK11           -------------------------------------------------- 71
CDK8            -------------------------------------------------- 71
IKKA            -------------------------------------------------- 67
IKKB            -------------------------------------------------- 67
1PHK            -------------------------------------------------- 76
PHKG1           -------------------------------------------------- 76
PHKG2           -------------------------------------------------- 75
CAMK2A          -------------------------------------------------- 68
CAMK2B          -------------------------------------------------- 68
CAMK2G          -------------------------------------------------- 68
CAMK2D          -------------------------------------------------- 68
CASK            -------------------------------------------------- 71
1IA8A           -------------------------------------------------- 64
CHK1            -------------------------------------------------- 67
CLK1            -------------------------------------------------- 72
CLK4            -------------------------------------------------- 71
CLK2            -------------------------------------------------- 72
CLK3            -------------------------------------------------- 72
MAP2K5          -------------------------------------------------- 67
MAP2K3          -------------------------------------------------- 68
MAP2K6          -------------------------------------------------- 68
MAP2K4          -------------------------------------------------- 68
MAP2K7          -------------------------------------------------- 68
MAP2K1          -------------------------------------------------- 67
MAP2K2          -------------------------------------------------- 67
CDKL5           -------------------------------------------------- 68
CDKL1           -------------------------------------------------- 68
CDKL4           -------------------------------------------------- 68
CDKL2           -------------------------------------------------- 68
CDKL3           -------------------------------------------------- 67
1I09B           -------------------------------------------------- 67
GSK3B           -------------------------------------------------- 67
1J1BA           -------------------------------------------------- 67
GSK3A           -------------------------------------------------- 67
LATS1           -------------------------------------------------- 68
LATS2           -------------------------------------------------- 68
NDR1            -------------------------------------------------- 68
NDR2            -------------------------------------------------- 68
MAST1           -------------------------------------------------- 68
MAST4           -------------------------------------------------- 68
MAST2           -------------------------------------------------- 68
MAST3           -------------------------------------------------- 68
MRCKA           -------------------------------------------------- 68
MRCKB           -------------------------------------------------- 68
DMPK2           -------------------------------------------------- 68
DMPK1           -------------------------------------------------- 68
ROCK1           -------------------------------------------------- 68
ROCK2           -------------------------------------------------- 68
CRIK            -------------------------------------------------- 68
MASTL           -------------------------------------------------- 66
1O6LA           -------------------------------------------------- 68
AKT2            -------------------------------------------------- 68
AKT1            -------------------------------------------------- 68
AKT3            -------------------------------------------------- 68
MSK1            -------------------------------------------------- 73
MSK2            -------------------------------------------------- 73
P70S6K          -------------------------------------------------- 72
P70S6KB         -------------------------------------------------- 72
RSK1            -------------------------------------------------- 70
RSK3            -------------------------------------------------- 70
RSK2            -------------------------------------------------- 70
RSK4            -------------------------------------------------- 70
1FOTA           -------------------------------------------------- 68
1CDKA           -------------------------------------------------- 68
PKACA           -------------------------------------------------- 68
PKACB           -------------------------------------------------- 68
PKACG           -------------------------------------------------- 68
PRKX            -------------------------------------------------- 68
PRKY            -------------------------------------------------- 68
PKCA            -------------------------------------------------- 69
PKCB            -------------------------------------------------- 69
PKCG            -------------------------------------------------- 74
PKCE            -------------------------------------------------- 69
PKCH            -------------------------------------------------- 69
PKCD            -------------------------------------------------- 69
PKCT            -------------------------------------------------- 69
PKCI            -------------------------------------------------- 69
PKCZ            -------------------------------------------------- 69
PKN1            -------------------------------------------------- 71
PKN2            -------------------------------------------------- 71
PKN3            -------------------------------------------------- 71
SGK             -------------------------------------------------- 69
SGK2            -------------------------------------------------- 69
SGK3            -------------------------------------------------- 69
PKG1            -------------------------------------------------- 69
PKG2            -------------------------------------------------- 68
AURB            -------------------------------------------------- 69
AURC            -------------------------------------------------- 69
AURA            -------------------------------------------------- 69
AURORA2_AVE     -------------------------------------------------- 69
PLK1            -------------------------------------------------- 69
PLK2            -------------------------------------------------- 69
PLK3            -------------------------------------------------- 69
PLK4            -------------------------------------------------- 69
NEK11           -------------------------------------------------- 71
YANK1           -------------------------------------------------- 68
YANK2           -------------------------------------------------- 68
YANK3           -------------------------------------------------- 68
SGK494          -------------------------------------------------- 68
DOMAIN2_MSK1    -------------------------------------------------- 66
DOMAIN2_MSK2    -------------------------------------------------- 60
DOMAIN2_RSK1    -------------------------------------------------- 65
DOMAIN2_RSK2    -------------------------------------------------- 65
DOMAIN2_RSK3    -------------------------------------------------- 65
DOMAIN2_RSK4    -------------------------------------------------- 65
DRAK1           -------------------------------------------------- 71
DRAK2           -------------------------------------------------- 71
1JKSA           -------------------------------------------------- 74
DAPK1           -------------------------------------------------- 74
DAPK3           -------------------------------------------------- 74
DAPK2           -------------------------------------------------- 74
SGK085          -------------------------------------------------- 68
CAMLCK          -------------------------------------------------- 68
SKMLCK          -------------------------------------------------- 68
SMMLCK          -------------------------------------------------- 68
1KOBA           -------------------------------------------------- 68
1TKIA           -------------------------------------------------- 67
TTN             -------------------------------------------------- 67
PKD1            -------------------------------------------------- 70
PKD3            -------------------------------------------------- 70
PKD2            -------------------------------------------------- 70
PSKH1           -------------------------------------------------- 68
PSKH2           -------------------------------------------------- 68
CAMK1A          -------------------------------------------------- 69
CAMK1D          -------------------------------------------------- 69
CAMK1B          -------------------------------------------------- 69
CAMK1G          -------------------------------------------------- 68
CAMK4           -------------------------------------------------- 66
DCAMKL1         -------------------------------------------------- 69
DCAMKL2         -------------------------------------------------- 69
DCAMKL3         -------------------------------------------------- 69
CHK2            -------------------------------------------------- 76
MAPKAPK2        -------------------------------------------------- 65
MAPKAPK3        -------------------------------------------------- 65
MAPKAPK5        -------------------------------------------------- 65
MNK1            -------------------------------------------------- 70
MNK2            -------------------------------------------------- 69
VACAMKL         -------------------------------------------------- 69
GCK             -------------------------------------------------- 66
KHS1            -------------------------------------------------- 66
KHS2            -------------------------------------------------- 66
HPK1            -------------------------------------------------- 66
MST1            -------------------------------------------------- 64
MST2            -------------------------------------------------- 64
MST3            -------------------------------------------------- 67
YSK1            -------------------------------------------------- 67
MST4            -------------------------------------------------- 67
LOK             -------------------------------------------------- 66
SLK             -------------------------------------------------- 66
MAP3K4          -------------------------------------------------- 68
MAP3K2          -------------------------------------------------- 71
MAP3K3          -------------------------------------------------- 71
MAP3K8          -------------------------------------------------- 71
MAP3K5          -------------------------------------------------- 71
MAP3K7          -------------------------------------------------- 64
MAP3K6          -------------------------------------------------- 61
PAK1            -------------------------------------------------- 66
PAK3            -------------------------------------------------- 66
PAK2            -------------------------------------------------- 66
PAK4            -------------------------------------------------- 66
PAK5            -------------------------------------------------- 66
PAK6            -------------------------------------------------- 66
OSR1            -------------------------------------------------- 67
STLK3           -------------------------------------------------- 67
TAO1            -------------------------------------------------- 69
TAO3            -------------------------------------------------- 69
TAO2            -------------------------------------------------- 69
MYO3A           -------------------------------------------------- 66
MYO3B           -------------------------------------------------- 66
ZC1/HGK         -------------------------------------------------- 66
ZC3/MINK        -------------------------------------------------- 66
ZC2/TNIK        -------------------------------------------------- 66
ZC4/NRK         -------------------------------------------------- 90
MAP3K1          -------------------------------------------------- 72
GAK             -------------------------------------------------- 73
SGK495          -------------------------------------------------- 0
TRB1            -------------------------------------------------- 52
TRB2            -------------------------------------------------- 57
TRB3            -------------------------------------------------- 55
SSTK            -------------------------------------------------- 68
TSSK3           -------------------------------------------------- 68
TSSK1           -------------------------------------------------- 68
TSSK2           -------------------------------------------------- 68
TSSK4           -------------------------------------------------- 68
HUNK            -------------------------------------------------- 70
SNRK            -------------------------------------------------- 67
NIM1            -------------------------------------------------- 67
MELK            -------------------------------------------------- 66
BRSK1           -------------------------------------------------- 67
BRSK2           -------------------------------------------------- 67
MARK1           -------------------------------------------------- 67
MARK2           -------------------------------------------------- 67
MARK3           -------------------------------------------------- 67
MARK4           -------------------------------------------------- 67
QIK             -------------------------------------------------- 67
SIK             -------------------------------------------------- 67
QSK             -------------------------------------------------- 67
AMPKA1          -------------------------------------------------- 68
AMPKA2          -------------------------------------------------- 68
NUAK1           -------------------------------------------------- 68
NUAK2           -------------------------------------------------- 67
BIKE            -------------------------------------------------- 70
AAK1            -------------------------------------------------- 70
LIMK1           -------------------------------------------------- 67
LIMK2           -------------------------------------------------- 67
TESK1           -------------------------------------------------- 65
TESK2           -------------------------------------------------- 55
WNK1            -------------------------------------------------- 71
WNK3            -------------------------------------------------- 71
WNK2            -------------------------------------------------- 71
WNK4            -------------------------------------------------- 71
NEK10           -------------------------------------------------- 78
NEK6            -------------------------------------------------- 70
NEK7            -------------------------------------------------- 70
NEK2            -------------------------------------------------- 69
NEK1            -------------------------------------------------- 69
NEK5            -------------------------------------------------- 69
NEK3            -------------------------------------------------- 68
NEK4            -------------------------------------------------- 69
NEK8            -------------------------------------------------- 69
NEK9            -------------------------------------------------- 69
NRBP1           -------------------------------------------------- 76
NRBP2           -------------------------------------------------- 76
CLIK1           -------------------------------------------------- 74
CLIK1L          -------------------------------------------------- 74
STK33           -------------------------------------------------- 67
DOMAIN2_GCN2    -------------------------------------------------- 78
SCYL1           -------------------------------------------------- 47
SCYL3           -------------------------------------------------- 40
DOMAIN2_JAK1    -------------------------------------------------- 67
DOMAIN2_TYK2    -------------------------------------------------- 81
DOMAIN2_JAK2    -------------------------------------------------- 64
DOMAIN2_JAK3    -------------------------------------------------- 63
ILK             -------------------------------------------------- 57
LRRK1           -------------------------------------------------- 77
PBK             -------------------------------------------------- 65
WEE1            -------------------------------------------------- 60
WEE1B           -------------------------------------------------- 60
SGK071          -------------------------------------------------- 57
PIK3R4          -------------------------------------------------- 50
MSSK1           -------------------------------------------------- 71
SRPK1           -------------------------------------------------- 71
SRPK2           -------------------------------------------------- 71
RSKL1           -------------------------------------------------- 46
RSKL2           -------------------------------------------------- 159
SGK396          -------------------------------------------------- 51
VRK1            -------------------------------------------------- 73
VRK2            -------------------------------------------------- 71
VRK3            -------------------------------------------------- 32
BUB1            -------------------------------------------------- 62
BUBR1           -------------------------------------------------- 69
SGK196          -------------------------------------------------- 53
SGK493          -------------------------------------------------- 70
                                                                  

DYRK1A          -------------------------------------------------- 66
DYRK1B          -------------------------------------------------- 66
DYRK2           -------------------------------------------------- 66
DYRK3           -------------------------------------------------- 66
DYRK4           -------------------------------------------------- 66
HIPK1           -------------------------------------------------- 65
HIPK2           -------------------------------------------------- 65
HIPK3           -------------------------------------------------- 65
HIPK4           -------------------------------------------------- 65
PRP4            -------------------------------------------------- 67
MOK             -------------------------------------------------- 63
1A6O            -------------------------------------------------- 59
1LPUA           -------------------------------------------------- 59
CK2A1           -------------------------------------------------- 59
CK2A1-RS        -------------------------------------------------- 59
CK2A2           -------------------------------------------------- 59
HSER            -------------------------------------------------- 51
SLOB            -------------------------------------------------- 64
CDC7            -------------------------------------------------- 63
1CSN            -------------------------------------------------- 60
CK1G1           -------------------------------------------------- 61
CK1G3           -------------------------------------------------- 60
CK1G2           -------------------------------------------------- 60
CK1A            -------------------------------------------------- 60
CK1A2           -------------------------------------------------- 60
1CKJA           -------------------------------------------------- 60
CK1D            -------------------------------------------------- 60
CK1E            -------------------------------------------------- 60
TTBK1           -------------------------------------------------- 60
TTBK2           -------------------------------------------------- 60
TLK1            -------------------------------------------------- 68
TLK2            -------------------------------------------------- 68
GPRK4           -------------------------------------------------- 64
GPRK6           -------------------------------------------------- 64
GPRK5           -------------------------------------------------- 64
RHOK            -------------------------------------------------- 64
GPRK7           -------------------------------------------------- 64
BARK1           -------------------------------------------------- 67
BARK2           -------------------------------------------------- 67
TTK             -------------------------------------------------- 64
RIPK1           -------------------------------------------------- 62
HASPIN          -------------------------------------------------- 69
GCN2            RSASA--RFPATGPGSSDDED---------------------DDEDEHGG 154
HRI             NNKSV--KYTTNLVIRESGEL---------------------ESTLELQE 161
KIS             -------------------------------------------------- 87
PDK1            ----------------QDDEK----------------------------- 73
PKR             -------------------------------------------------- 65
PEK             QTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGN 187
PRPK            -------------------------------------------------- 73
DOMAIN2_OBSCN   -------------------------------------------------- 66
DOMAIN2_SPEG    -------------------------------------------------- 66
LMR1            -------------------------------------------------- 70
LMR2            -------------------------------------------------- 70
LMR3            -------------------------------------------------- 70
SGK307          -------------------------------------------------- 6
STLK5           -------------------------------------------------- 71
STLK6           -------------------------------------------------- 71
STLK6-RS        -------------------------------------------------- 71
OBSCN           -------------------------------------------------- 66
SPEG            -------------------------------------------------- 66
TRAD            -------------------------------------------------- 66
TRIO            -------------------------------------------------- 66
SGK223          -------------------------------------------------- 67
SGK269          -------------------------------------------------- 70
ALK1            -------------------------------------------------- 65
ALK2            -------------------------------------------------- 65
IRAK4           -------------------------------------------------- 70
BMPR2           -------------------------------------------------- 65
TGFBR2          -------------------------------------------------- 71
ACTR2           -------------------------------------------------- 65
ACTR2B          -------------------------------------------------- 65
1B6CB           -------------------------------------------------- 65
TGFBR1          -------------------------------------------------- 65
ALK4            -------------------------------------------------- 65
ALK7            -------------------------------------------------- 65
BMPR1A          -------------------------------------------------- 65
BMPR1B          -------------------------------------------------- 65
IRAK1           -------------------------------------------------- 70
IRAK2           -------------------------------------------------- 73
IRAK3           -------------------------------------------------- 73
MISR2           -------------------------------------------------- 68
MYT1            -------------------------------------------------- 74
SBK             -------------------------------------------------- 71
SGK110          -------------------------------------------------- 71
SGK069          -------------------------------------------------- 71
SGK496          -------------------------------------------------- 72
NIK             -------------------------------------------------- 66
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 77
IKKE            -------------------------------------------------- 72
TBK1            -------------------------------------------------- 72
MOS             -------------------------------------------------- 71
LKB1            -------------------------------------------------- 75
CAMKK1          -------------------------------------------------- 106
CAMKK2          -------------------------------------------------- 97
PASK            -------------------------------------------------- 79
PIM1            -------------------------------------------------- 79
PIM3            -------------------------------------------------- 80
PIM2            -------------------------------------------------- 81
COT             -------------------------------------------------- 68
SCYL2           -------------------------------------------------- 83
FUSED           -------------------------------------------------- 66
ULK1            -------------------------------------------------- 66
ULK2            -------------------------------------------------- 66
ULK3            -------------------------------------------------- 67
ULK4            -------------------------------------------------- 61
IRE1            -------------------------------------------------- 61
IRE2            -------------------------------------------------- 61
RNASEL          -------------------------------------------------- 55
MPSK1           -------------------------------------------------- 67
PINK1           -------------------------------------------------- 134
ALK             -------------------------------------------------- 73
LTK             -------------------------------------------------- 73
ROS             -------------------------------------------------- 74
IGF1R           -------------------------------------------------- 73
1IR3A           -------------------------------------------------- 73
INSR            -------------------------------------------------- 73
IRR             -------------------------------------------------- 73
1M14A           -------------------------------------------------- 72
EGFR            -------------------------------------------------- 72
HER2/ERBB2      -------------------------------------------------- 72
HER4/ERBB4      -------------------------------------------------- 72
HER3/ERBB3      -------------------------------------------------- 72
ITK             -------------------------------------------------- 65
TEC             -------------------------------------------------- 65
TXK             -------------------------------------------------- 65
BMX             -------------------------------------------------- 65
1K2PA           -------------------------------------------------- 65
BTK             -------------------------------------------------- 65
CCK4            -------------------------------------------------- 72
ROR1            -------------------------------------------------- 72
ROR2            -------------------------------------------------- 73
MUSK            -------------------------------------------------- 73
TRKA            -------------------------------------------------- 72
TRKB            -------------------------------------------------- 72
TRKC            -------------------------------------------------- 72
DDR1            -------------------------------------------------- 84
DDR2            -------------------------------------------------- 84
RYK             -------------------------------------------------- 73
JAK1            -------------------------------------------------- 72
JAK2            -------------------------------------------------- 72
JAK3            -------------------------------------------------- 72
ACK             -------------------------------------------------- 74
TYK2            -------------------------------------------------- 73
TNK1            -------------------------------------------------- 75
EPHA1           -------------------------------------------------- 71
EPHA10          -------------------------------------------------- 71
FAK             -------------------------------------------------- 71
EPHB6           -------------------------------------------------- 71
EPHA2           -------------------------------------------------- 72
EPHA8           -------------------------------------------------- 71
EPHA6           -------------------------------------------------- 77
EPHB1           -------------------------------------------------- 71
EPHB2           -------------------------------------------------- 71
EPHB3           -------------------------------------------------- 71
EPHB4           -------------------------------------------------- 71
EPHA7           -------------------------------------------------- 71
EPHA4           -------------------------------------------------- 71
EPHA3           -------------------------------------------------- 71
EPHA5           -------------------------------------------------- 71
PYK2            -------------------------------------------------- 71
CSK             -------------------------------------------------- 63
CTK             -------------------------------------------------- 63
1IEPA           -------------------------------------------------- 66
ABL             -------------------------------------------------- 66
ARG             -------------------------------------------------- 66
BRK             -------------------------------------------------- 67
SRM             -------------------------------------------------- 66
FRK             -------------------------------------------------- 66
FGR             -------------------------------------------------- 65
FYN             -------------------------------------------------- 65
SRC             -------------------------------------------------- 65
YES             -------------------------------------------------- 65
HCK             -------------------------------------------------- 65
LYN             -------------------------------------------------- 66
3LCK            -------------------------------------------------- 65
LCK             -------------------------------------------------- 65
BLK             -------------------------------------------------- 65
FER             -------------------------------------------------- 68
FES             -------------------------------------------------- 69
SYK             -------------------------------------------------- 72
ZAP70           -------------------------------------------------- 71
FGFR1           -------------------------------------------------- 78
FGFR2           -------------------------------------------------- 78
FGFR3           -------------------------------------------------- 78
FGFR4           -------------------------------------------------- 78
RET             -------------------------------------------------- 75
TIE1            -------------------------------------------------- 73
1FVRA           -------------------------------------------------- 73
TIE2            -------------------------------------------------- 73
FLT1            -------------------------------------------------- 77
KDR             -------------------------------------------------- 77
KDR_AVE         -------------------------------------------------- 77
FLT4            -------------------------------------------------- 77
FMS             -------------------------------------------------- 76
FLT3            -------------------------------------------------- 76
KIT             -------------------------------------------------- 76
PDGFRA          -------------------------------------------------- 76
PDGFRB          -------------------------------------------------- 76
MER             -------------------------------------------------- 76
AXL             -------------------------------------------------- 75
TYRO3           -------------------------------------------------- 76
MET             -------------------------------------------------- 74
RON             -------------------------------------------------- 74
HH498           -------------------------------------------------- 68
LZK             -------------------------------------------------- 56
DLK             -------------------------------------------------- 56
MLK1            -------------------------------------------------- 67
MLK3            -------------------------------------------------- 67
MLK2            -------------------------------------------------- 67
MLK4            -------------------------------------------------- 67
ZAK             -------------------------------------------------- 57
TAK1            -------------------------------------------------- 61
KSR1            -------------------------------------------------- 64
KSR2            -------------------------------------------------- 64
ARAF            -------------------------------------------------- 66
RAF1            -------------------------------------------------- 66
BRAF            -------------------------------------------------- 64
LRRK2           -------------------------------------------------- 61
ANKRD3          -------------------------------------------------- 67
SGK288          -------------------------------------------------- 66
RIPK2           -------------------------------------------------- 68
RIPK3           -------------------------------------------------- 63
MLKL            -------------------------------------------------- 68
ANPA            -------------------------------------------------- 68
ANPB            -------------------------------------------------- 68
CYGD            -------------------------------------------------- 73
CYGF            -------------------------------------------------- 82
TBCK            -------------------------------------------------- 46
ERK1            -------------------------------------------------- 70
3ERK            -------------------------------------------------- 70
ERK2            -------------------------------------------------- 70
ERK5            -------------------------------------------------- 72
1JNK            -------------------------------------------------- 72
1PMNA           -------------------------------------------------- 72
JNK3            -------------------------------------------------- 72
JNK1            -------------------------------------------------- 72
JNK2            -------------------------------------------------- 72
1P38            -------------------------------------------------- 72
P38A            -------------------------------------------------- 72
P38B            -------------------------------------------------- 72
P38D            -------------------------------------------------- 72
P38G            -------------------------------------------------- 72
NLK             -------------------------------------------------- 71
ERK7            -------------------------------------------------- 90
ERK3            -------------------------------------------------- 73
ERK4            -------------------------------------------------- 71
ICK             -------------------------------------------------- 70
MAK             -------------------------------------------------- 70
PCTAIRE1        -------------------------------------------------- 70
PCTAIRE2        -------------------------------------------------- 70
PCTAIRE3        -------------------------------------------------- 70
PFTAIRE1        -------------------------------------------------- 70
PFTAIRE2        -------------------------------------------------- 70
CDC2            -------------------------------------------------- 71
1HCL            -------------------------------------------------- 67
CDK2            -------------------------------------------------- 71
CDK3            -------------------------------------------------- 71
CDK5            -------------------------------------------------- 71
CDK7            -------------------------------------------------- 74
CDK4            -------------------------------------------------- 79
1BLXA           -------------------------------------------------- 77
CDK6            -------------------------------------------------- 77
PITSLRE         -------------------------------------------------- 71
CDK10           -------------------------------------------------- 71
CDK9            -------------------------------------------------- 73
CHED            -------------------------------------------------- 73
CRK7            -------------------------------------------------- 73
CCRK            -------------------------------------------------- 72
CDK11           -------------------------------------------------- 71
CDK8            -------------------------------------------------- 71
IKKA            -------------------------------------------------- 67
IKKB            -------------------------------------------------- 67
1PHK            -------------------------------------------------- 76
PHKG1           -------------------------------------------------- 76
PHKG2           -------------------------------------------------- 75
CAMK2A          -------------------------------------------------- 68
CAMK2B          -------------------------------------------------- 68
CAMK2G          -------------------------------------------------- 68
CAMK2D          -------------------------------------------------- 68
CASK            -------------------------------------------------- 71
1IA8A           -------------------------------------------------- 64
CHK1            -------------------------------------------------- 67
CLK1            -------------------------------------------------- 72
CLK4            -------------------------------------------------- 71
CLK2            -------------------------------------------------- 72
CLK3            -------------------------------------------------- 72
MAP2K5          -------------------------------------------------- 67
MAP2K3          -------------------------------------------------- 68
MAP2K6          -------------------------------------------------- 68
MAP2K4          -------------------------------------------------- 68
MAP2K7          -------------------------------------------------- 68
MAP2K1          -------------------------------------------------- 67
MAP2K2          -------------------------------------------------- 67
CDKL5           -------------------------------------------------- 68
CDKL1           -------------------------------------------------- 68
CDKL4           -------------------------------------------------- 68
CDKL2           -------------------------------------------------- 68
CDKL3           -------------------------------------------------- 67
1I09B           -------------------------------------------------- 67
GSK3B           -------------------------------------------------- 67
1J1BA           -------------------------------------------------- 67
GSK3A           -------------------------------------------------- 67
LATS1           -------------------------------------------------- 68
LATS2           -------------------------------------------------- 68
NDR1            -------------------------------------------------- 68
NDR2            -------------------------------------------------- 68
MAST1           -------------------------------------------------- 68
MAST4           -------------------------------------------------- 68
MAST2           -------------------------------------------------- 68
MAST3           -------------------------------------------------- 68
MRCKA           -------------------------------------------------- 68
MRCKB           -------------------------------------------------- 68
DMPK2           -------------------------------------------------- 68
DMPK1           -------------------------------------------------- 68
ROCK1           -------------------------------------------------- 68
ROCK2           -------------------------------------------------- 68
CRIK            -------------------------------------------------- 68
MASTL           -------------------------------------------------- 66
1O6LA           -------------------------------------------------- 68
AKT2            -------------------------------------------------- 68
AKT1            -------------------------------------------------- 68
AKT3            -------------------------------------------------- 68
MSK1            -------------------------------------------------- 73
MSK2            -------------------------------------------------- 73
P70S6K          -------------------------------------------------- 72
P70S6KB         -------------------------------------------------- 72
RSK1            -------------------------------------------------- 70
RSK3            -------------------------------------------------- 70
RSK2            -------------------------------------------------- 70
RSK4            -------------------------------------------------- 70
1FOTA           -------------------------------------------------- 68
1CDKA           -------------------------------------------------- 68
PKACA           -------------------------------------------------- 68
PKACB           -------------------------------------------------- 68
PKACG           -------------------------------------------------- 68
PRKX            -------------------------------------------------- 68
PRKY            -------------------------------------------------- 68
PKCA            -------------------------------------------------- 69
PKCB            -------------------------------------------------- 69
PKCG            -------------------------------------------------- 74
PKCE            -------------------------------------------------- 69
PKCH            -------------------------------------------------- 69
PKCD            -------------------------------------------------- 69
PKCT            -------------------------------------------------- 69
PKCI            -------------------------------------------------- 69
PKCZ            -------------------------------------------------- 69
PKN1            -------------------------------------------------- 71
PKN2            -------------------------------------------------- 71
PKN3            -------------------------------------------------- 71
SGK             -------------------------------------------------- 69
SGK2            -------------------------------------------------- 69
SGK3            -------------------------------------------------- 69
PKG1            -------------------------------------------------- 69
PKG2            -------------------------------------------------- 68
AURB            -------------------------------------------------- 69
AURC            -------------------------------------------------- 69
AURA            -------------------------------------------------- 69
AURORA2_AVE     -------------------------------------------------- 69
PLK1            -------------------------------------------------- 69
PLK2            -------------------------------------------------- 69
PLK3            -------------------------------------------------- 69
PLK4            -------------------------------------------------- 69
NEK11           -------------------------------------------------- 71
YANK1           -------------------------------------------------- 68
YANK2           -------------------------------------------------- 68
YANK3           -------------------------------------------------- 68
SGK494          -------------------------------------------------- 68
DOMAIN2_MSK1    -------------------------------------------------- 66
DOMAIN2_MSK2    -------------------------------------------------- 60
DOMAIN2_RSK1    -------------------------------------------------- 65
DOMAIN2_RSK2    -------------------------------------------------- 65
DOMAIN2_RSK3    -------------------------------------------------- 65
DOMAIN2_RSK4    -------------------------------------------------- 65
DRAK1           -------------------------------------------------- 71
DRAK2           -------------------------------------------------- 71
1JKSA           -------------------------------------------------- 74
DAPK1           -------------------------------------------------- 74
DAPK3           -------------------------------------------------- 74
DAPK2           -------------------------------------------------- 74
SGK085          -------------------------------------------------- 68
CAMLCK          -------------------------------------------------- 68
SKMLCK          -------------------------------------------------- 68
SMMLCK          -------------------------------------------------- 68
1KOBA           -------------------------------------------------- 68
1TKIA           -------------------------------------------------- 67
TTN             -------------------------------------------------- 67
PKD1            -------------------------------------------------- 70
PKD3            -------------------------------------------------- 70
PKD2            -------------------------------------------------- 70
PSKH1           -------------------------------------------------- 68
PSKH2           -------------------------------------------------- 68
CAMK1A          -------------------------------------------------- 69
CAMK1D          -------------------------------------------------- 69
CAMK1B          -------------------------------------------------- 69
CAMK1G          -------------------------------------------------- 68
CAMK4           -------------------------------------------------- 66
DCAMKL1         -------------------------------------------------- 69
DCAMKL2         -------------------------------------------------- 69
DCAMKL3         -------------------------------------------------- 69
CHK2            -------------------------------------------------- 76
MAPKAPK2        -------------------------------------------------- 65
MAPKAPK3        -------------------------------------------------- 65
MAPKAPK5        -------------------------------------------------- 65
MNK1            -------------------------------------------------- 70
MNK2            -------------------------------------------------- 69
VACAMKL         -------------------------------------------------- 69
GCK             -------------------------------------------------- 66
KHS1            -------------------------------------------------- 66
KHS2            -------------------------------------------------- 66
HPK1            -------------------------------------------------- 66
MST1            -------------------------------------------------- 64
MST2            -------------------------------------------------- 64
MST3            -------------------------------------------------- 67
YSK1            -------------------------------------------------- 67
MST4            -------------------------------------------------- 67
LOK             -------------------------------------------------- 66
SLK             -------------------------------------------------- 66
MAP3K4          -------------------------------------------------- 68
MAP3K2          -------------------------------------------------- 71
MAP3K3          -------------------------------------------------- 71
MAP3K8          -------------------------------------------------- 71
MAP3K5          -------------------------------------------------- 71
MAP3K7          -------------------------------------------------- 64
MAP3K6          -------------------------------------------------- 61
PAK1            -------------------------------------------------- 66
PAK3            -------------------------------------------------- 66
PAK2            -------------------------------------------------- 66
PAK4            -------------------------------------------------- 66
PAK5            -------------------------------------------------- 66
PAK6            -------------------------------------------------- 66
OSR1            -------------------------------------------------- 67
STLK3           -------------------------------------------------- 67
TAO1            -------------------------------------------------- 69
TAO3            -------------------------------------------------- 69
TAO2            -------------------------------------------------- 69
MYO3A           -------------------------------------------------- 66
MYO3B           -------------------------------------------------- 66
ZC1/HGK         -------------------------------------------------- 66
ZC3/MINK        -------------------------------------------------- 66
ZC2/TNIK        -------------------------------------------------- 66
ZC4/NRK         -------------------------------------------------- 90
MAP3K1          -------------------------------------------------- 72
GAK             -------------------------------------------------- 73
SGK495          -------------------------------------------------- 0
TRB1            -------------------------------------------------- 52
TRB2            -------------------------------------------------- 57
TRB3            -------------------------------------------------- 55
SSTK            -------------------------------------------------- 68
TSSK3           -------------------------------------------------- 68
TSSK1           -------------------------------------------------- 68
TSSK2           -------------------------------------------------- 68
TSSK4           -------------------------------------------------- 68
HUNK            -------------------------------------------------- 70
SNRK            -------------------------------------------------- 67
NIM1            -------------------------------------------------- 67
MELK            -------------------------------------------------- 66
BRSK1           -------------------------------------------------- 67
BRSK2           -------------------------------------------------- 67
MARK1           -------------------------------------------------- 67
MARK2           -------------------------------------------------- 67
MARK3           -------------------------------------------------- 67
MARK4           -------------------------------------------------- 67
QIK             -------------------------------------------------- 67
SIK             -------------------------------------------------- 67
QSK             -------------------------------------------------- 67
AMPKA1          -------------------------------------------------- 68
AMPKA2          -------------------------------------------------- 68
NUAK1           -------------------------------------------------- 68
NUAK2           -------------------------------------------------- 67
BIKE            -------------------------------------------------- 70
AAK1            -------------------------------------------------- 70
LIMK1           -------------------------------------------------- 67
LIMK2           -------------------------------------------------- 67
TESK1           -------------------------------------------------- 65
TESK2           -------------------------------------------------- 55
WNK1            -------------------------------------------------- 71
WNK3            -------------------------------------------------- 71
WNK2            -------------------------------------------------- 71
WNK4            -------------------------------------------------- 71
NEK10           -------------------------------------------------- 78
NEK6            -------------------------------------------------- 70
NEK7            -------------------------------------------------- 70
NEK2            -------------------------------------------------- 69
NEK1            -------------------------------------------------- 69
NEK5            -------------------------------------------------- 69
NEK3            -------------------------------------------------- 68
NEK4            -------------------------------------------------- 69
NEK8            -------------------------------------------------- 69
NEK9            -------------------------------------------------- 69
NRBP1           -------------------------------------------------- 76
NRBP2           -------------------------------------------------- 76
CLIK1           -------------------------------------------------- 74
CLIK1L          -------------------------------------------------- 74
STK33           -------------------------------------------------- 67
DOMAIN2_GCN2    -------------------------------------------------- 78
SCYL1           -------------------------------------------------- 47
SCYL3           -------------------------------------------------- 40
DOMAIN2_JAK1    -------------------------------------------------- 67
DOMAIN2_TYK2    -------------------------------------------------- 81
DOMAIN2_JAK2    -------------------------------------------------- 64
DOMAIN2_JAK3    -------------------------------------------------- 63
ILK             -------------------------------------------------- 57
LRRK1           -------------------------------------------------- 77
PBK             -------------------------------------------------- 65
WEE1            -------------------------------------------------- 60
WEE1B           -------------------------------------------------- 60
SGK071          -------------------------------------------------- 57
PIK3R4          -------------------------------------------------- 50
MSSK1           -------------------------------------------------- 71
SRPK1           -------------------------------------------------- 71
SRPK2           -------------------------------------------------- 71
RSKL1           -------------------------------------------------- 46
RSKL2           -------------------------------------------------- 159
SGK396          -------------------------------------------------- 51
VRK1            -------------------------------------------------- 73
VRK2            -------------------------------------------------- 71
VRK3            -------------------------------------------------- 32
BUB1            -------------------------------------------------- 62
BUBR1           -------------------------------------------------- 69
SGK196          -------------------------------------------------- 53
SGK493          -------------------------------------------------- 70
                                                                  

DYRK1A          -------------------------------------------------- 66
DYRK1B          -------------------------------------------------- 66
DYRK2           -------------------------------------------------- 66
DYRK3           -------------------------------------------------- 66
DYRK4           -------------------------------------------------- 66
HIPK1           -------------------------------------------------- 65
HIPK2           -------------------------------------------------- 65
HIPK3           -------------------------------------------------- 65
HIPK4           -------------------------------------------------- 65
PRP4            -------------------------------------------------- 67
MOK             -------------------------------------------------- 63
1A6O            -------------------------------------------------- 59
1LPUA           -------------------------------------------------- 59
CK2A1           -------------------------------------------------- 59
CK2A1-RS        -------------------------------------------------- 59
CK2A2           -------------------------------------------------- 59
HSER            -------------------------------------------------- 51
SLOB            -------------------------------------------------- 64
CDC7            -------------------------------------------------- 63
1CSN            -------------------------------------------------- 60
CK1G1           -------------------------------------------------- 61
CK1G3           -------------------------------------------------- 60
CK1G2           -------------------------------------------------- 60
CK1A            -------------------------------------------------- 60
CK1A2           -------------------------------------------------- 60
1CKJA           -------------------------------------------------- 60
CK1D            -------------------------------------------------- 60
CK1E            -------------------------------------------------- 60
TTBK1           -------------------------------------------------- 60
TTBK2           -------------------------------------------------- 60
TLK1            -------------------------------------------------- 68
TLK2            -------------------------------------------------- 68
GPRK4           -------------------------------------------------- 64
GPRK6           -------------------------------------------------- 64
GPRK5           -------------------------------------------------- 64
RHOK            -------------------------------------------------- 64
GPRK7           -------------------------------------------------- 64
BARK1           -------------------------------------------------- 67
BARK2           -------------------------------------------------- 67
TTK             -------------------------------------------------- 64
RIPK1           -------------------------------------------------- 62
HASPIN          -------------------------------------------------- 69
GCN2            VFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEKNGCHE-------- 196
HRI             NGLAGLSASSIVEQQLPLRRNSHLEESFTSTEESSEENVNFL-------- 203
KIS             ---------------------------LLEL------------------- 91
PDK1            -------------------------------------------------- 73
PKR             -----------------YDPETSDDSLESSD------------------- 79
PEK             DEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHI 237
PRPK            --------------------------------YASN-------------- 77
DOMAIN2_OBSCN   -------------------------------------------------- 66
DOMAIN2_SPEG    -------------------------------------------------- 66
LMR1            -------------------------------------------------- 70
LMR2            -------------------------------------------------- 70
LMR3            -------------------------------------------------- 70
SGK307          -------------------------------------------------- 6
STLK5           -------------------------------------------------- 71
STLK6           -------------------------------------------------- 71
STLK6-RS        -------------------------------------------------- 71
OBSCN           -------------------------------------------------- 66
SPEG            -------------------------------------------------- 66
TRAD            -------------------------------------------------- 66
TRIO            -------------------------------------------------- 66
SGK223          -------------------------------------------------- 67
SGK269          -------------------------------------------------- 70
ALK1            -------------------------------------------------- 65
ALK2            -------------------------------------------------- 65
IRAK4           -------------------------------------------------- 70
BMPR2           -------------------------------------------------- 65
TGFBR2          -------------------------------------------------- 71
ACTR2           -------------------------------------------------- 65
ACTR2B          -------------------------------------------------- 65
1B6CB           -------------------------------------------------- 65
TGFBR1          -------------------------------------------------- 65
ALK4            -------------------------------------------------- 65
ALK7            -------------------------------------------------- 65
BMPR1A          -------------------------------------------------- 65
BMPR1B          -------------------------------------------------- 65
IRAK1           -------------------------------------------------- 70
IRAK2           -------------------------------------------------- 73
IRAK3           -------------------------------------------------- 73
MISR2           -------------------------------------------------- 68
MYT1            -------------------------------------------------- 74
SBK             -------------------------------------------------- 71
SGK110          -------------------------------------------------- 71
SGK069          -------------------------------------------------- 71
SGK496          -------------------------------------------------- 72
NIK             -------------------------------------------------- 66
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 77
IKKE            -------------------------------------------------- 72
TBK1            -------------------------------------------------- 72
MOS             -------------------------------------------------- 71
LKB1            -------------------------------------------------- 75
CAMKK1          -------------------------------------------------- 106
CAMKK2          -------------------------------------------------- 97
PASK            -------------------------------------------------- 79
PIM1            -------------------------------------------------- 79
PIM3            -------------------------------------------------- 80
PIM2            -------------------------------------------------- 81
COT             -------------------------------------------------- 68
SCYL2           -------------------------------------------------- 83
FUSED           -------------------------------------------------- 66
ULK1            -------------------------------------------------- 66
ULK2            -------------------------------------------------- 66
ULK3            -------------------------------------------------- 67
ULK4            -------------------------------------------------- 61
IRE1            -------------------------------------------------- 61
IRE2            -------------------------------------------------- 61
RNASEL          -------------------------------------------------- 55
MPSK1           -------------------------------------------------- 67
PINK1           -------------------------------------------------- 134
ALK             -------------------------------------------------- 73
LTK             -------------------------------------------------- 73
ROS             -------------------------------------------------- 74
IGF1R           -------------------------------------------------- 73
1IR3A           -------------------------------------------------- 73
INSR            -------------------------------------------------- 73
IRR             -------------------------------------------------- 73
1M14A           -------------------------------------------------- 72
EGFR            -------------------------------------------------- 72
HER2/ERBB2      -------------------------------------------------- 72
HER4/ERBB4      -------------------------------------------------- 72
HER3/ERBB3      -------------------------------------------------- 72
ITK             -------------------------------------------------- 65
TEC             -------------------------------------------------- 65
TXK             -------------------------------------------------- 65
BMX             -------------------------------------------------- 65
1K2PA           -------------------------------------------------- 65
BTK             -------------------------------------------------- 65
CCK4            -------------------------------------------------- 72
ROR1            -------------------------------------------------- 72
ROR2            -------------------------------------------------- 73
MUSK            -------------------------------------------------- 73
TRKA            -------------------------------------------------- 72
TRKB            -------------------------------------------------- 72
TRKC            -------------------------------------------------- 72
DDR1            -------------------------------------------------- 84
DDR2            -------------------------------------------------- 84
RYK             -------------------------------------------------- 73
JAK1            -------------------------------------------------- 72
JAK2            -------------------------------------------------- 72
JAK3            -------------------------------------------------- 72
ACK             -------------------------------------------------- 74
TYK2            -------------------------------------------------- 73
TNK1            -------------------------------------------------- 75
EPHA1           -------------------------------------------------- 71
EPHA10          -------------------------------------------------- 71
FAK             -------------------------------------------------- 71
EPHB6           -------------------------------------------------- 71
EPHA2           -------------------------------------------------- 72
EPHA8           -------------------------------------------------- 71
EPHA6           -------------------------------------------------- 77
EPHB1           -------------------------------------------------- 71
EPHB2           -------------------------------------------------- 71
EPHB3           -------------------------------------------------- 71
EPHB4           -------------------------------------------------- 71
EPHA7           -------------------------------------------------- 71
EPHA4           -------------------------------------------------- 71
EPHA3           -------------------------------------------------- 71
EPHA5           -------------------------------------------------- 71
PYK2            -------------------------------------------------- 71
CSK             -------------------------------------------------- 63
CTK             -------------------------------------------------- 63
1IEPA           -------------------------------------------------- 66
ABL             -------------------------------------------------- 66
ARG             -------------------------------------------------- 66
BRK             -------------------------------------------------- 67
SRM             -------------------------------------------------- 66
FRK             -------------------------------------------------- 66
FGR             -------------------------------------------------- 65
FYN             -------------------------------------------------- 65
SRC             -------------------------------------------------- 65
YES             -------------------------------------------------- 65
HCK             -------------------------------------------------- 65
LYN             -------------------------------------------------- 66
3LCK            -------------------------------------------------- 65
LCK             -------------------------------------------------- 65
BLK             -------------------------------------------------- 65
FER             -------------------------------------------------- 68
FES             -------------------------------------------------- 69
SYK             -------------------------------------------------- 72
ZAP70           -------------------------------------------------- 71
FGFR1           -------------------------------------------------- 78
FGFR2           -------------------------------------------------- 78
FGFR3           -------------------------------------------------- 78
FGFR4           -------------------------------------------------- 78
RET             -------------------------------------------------- 75
TIE1            -------------------------------------------------- 73
1FVRA           -------------------------------------------------- 73
TIE2            -------------------------------------------------- 73
FLT1            -------------------------------------------------- 77
KDR             -------------------------------------------------- 77
KDR_AVE         -------------------------------------------------- 77
FLT4            -------------------------------------------------- 77
FMS             -------------------------------------------------- 76
FLT3            -------------------------------------------------- 76
KIT             -------------------------------------------------- 76
PDGFRA          -------------------------------------------------- 76
PDGFRB          -------------------------------------------------- 76
MER             -------------------------------------------------- 76
AXL             -------------------------------------------------- 75
TYRO3           -------------------------------------------------- 76
MET             -------------------------------------------------- 74
RON             -------------------------------------------------- 74
HH498           -------------------------------------------------- 68
LZK             -------------------------------------------------- 56
DLK             -------------------------------------------------- 56
MLK1            -------------------------------------------------- 67
MLK3            -------------------------------------------------- 67
MLK2            -------------------------------------------------- 67
MLK4            -------------------------------------------------- 67
ZAK             -------------------------------------------------- 57
TAK1            -------------------------------------------------- 61
KSR1            -------------------------------------------------- 64
KSR2            -------------------------------------------------- 64
ARAF            -------------------------------------------------- 66
RAF1            -------------------------------------------------- 66
BRAF            -------------------------------------------------- 64
LRRK2           -------------------------------------------------- 61
ANKRD3          -------------------------------------------------- 67
SGK288          -------------------------------------------------- 66
RIPK2           -------------------------------------------------- 68
RIPK3           -------------------------------------------------- 63
MLKL            -------------------------------------------------- 68
ANPA            -------------------------------------------------- 68
ANPB            -------------------------------------------------- 68
CYGD            -------------------------------------------------- 73
CYGF            -------------------------------------------------- 82
TBCK            -------------------------------------------------- 46
ERK1            -------------------------------------------------- 70
3ERK            -------------------------------------------------- 70
ERK2            -------------------------------------------------- 70
ERK5            -------------------------------------------------- 72
1JNK            -------------------------------------------------- 72
1PMNA           -------------------------------------------------- 72
JNK3            -------------------------------------------------- 72
JNK1            -------------------------------------------------- 72
JNK2            -------------------------------------------------- 72
1P38            -------------------------------------------------- 72
P38A            -------------------------------------------------- 72
P38B            -------------------------------------------------- 72
P38D            -------------------------------------------------- 72
P38G            -------------------------------------------------- 72
NLK             -------------------------------------------------- 71
ERK7            -------------------------------------------------- 90
ERK3            -------------------------------------------------- 73
ERK4            -------------------------------------------------- 71
ICK             -------------------------------------------------- 70
MAK             -------------------------------------------------- 70
PCTAIRE1        -------------------------------------------------- 70
PCTAIRE2        -------------------------------------------------- 70
PCTAIRE3        -------------------------------------------------- 70
PFTAIRE1        -------------------------------------------------- 70
PFTAIRE2        -------------------------------------------------- 70
CDC2            -------------------------------------------------- 71
1HCL            -------------------------------------------------- 67
CDK2            -------------------------------------------------- 71
CDK3            -------------------------------------------------- 71
CDK5            -------------------------------------------------- 71
CDK7            -------------------------------------------------- 74
CDK4            -------------------------------------------------- 79
1BLXA           -------------------------------------------------- 77
CDK6            -------------------------------------------------- 77
PITSLRE         -------------------------------------------------- 71
CDK10           -------------------------------------------------- 71
CDK9            -------------------------------------------------- 73
CHED            -------------------------------------------------- 73
CRK7            -------------------------------------------------- 73
CCRK            -------------------------------------------------- 72
CDK11           -------------------------------------------------- 71
CDK8            -------------------------------------------------- 71
IKKA            -------------------------------------------------- 67
IKKB            -------------------------------------------------- 67
1PHK            -------------------------------------------------- 76
PHKG1           -------------------------------------------------- 76
PHKG2           -------------------------------------------------- 75
CAMK2A          -------------------------------------------------- 68
CAMK2B          -------------------------------------------------- 68
CAMK2G          -------------------------------------------------- 68
CAMK2D          -------------------------------------------------- 68
CASK            -------------------------------------------------- 71
1IA8A           -------------------------------------------------- 64
CHK1            -------------------------------------------------- 67
CLK1            -------------------------------------------------- 72
CLK4            -------------------------------------------------- 71
CLK2            -------------------------------------------------- 72
CLK3            -------------------------------------------------- 72
MAP2K5          -------------------------------------------------- 67
MAP2K3          -------------------------------------------------- 68
MAP2K6          -------------------------------------------------- 68
MAP2K4          -------------------------------------------------- 68
MAP2K7          -------------------------------------------------- 68
MAP2K1          -------------------------------------------------- 67
MAP2K2          -------------------------------------------------- 67
CDKL5           -------------------------------------------------- 68
CDKL1           -------------------------------------------------- 68
CDKL4           -------------------------------------------------- 68
CDKL2           -------------------------------------------------- 68
CDKL3           -------------------------------------------------- 67
1I09B           -------------------------------------------------- 67
GSK3B           -------------------------------------------------- 67
1J1BA           -------------------------------------------------- 67
GSK3A           -------------------------------------------------- 67
LATS1           -------------------------------------------------- 68
LATS2           -------------------------------------------------- 68
NDR1            -------------------------------------------------- 68
NDR2            -------------------------------------------------- 68
MAST1           -------------------------------------------------- 68
MAST4           -------------------------------------------------- 68
MAST2           -------------------------------------------------- 68
MAST3           -------------------------------------------------- 68
MRCKA           -------------------------------------------------- 68
MRCKB           -------------------------------------------------- 68
DMPK2           -------------------------------------------------- 68
DMPK1           -------------------------------------------------- 68
ROCK1           -------------------------------------------------- 68
ROCK2           -------------------------------------------------- 68
CRIK            -------------------------------------------------- 68
MASTL           -------------------------------------------------- 66
1O6LA           -------------------------------------------------- 68
AKT2            -------------------------------------------------- 68
AKT1            -------------------------------------------------- 68
AKT3            -------------------------------------------------- 68
MSK1            -------------------------------------------------- 73
MSK2            -------------------------------------------------- 73
P70S6K          -------------------------------------------------- 72
P70S6KB         -------------------------------------------------- 72
RSK1            -------------------------------------------------- 70
RSK3            -------------------------------------------------- 70
RSK2            -------------------------------------------------- 70
RSK4            -------------------------------------------------- 70
1FOTA           -------------------------------------------------- 68
1CDKA           -------------------------------------------------- 68
PKACA           -------------------------------------------------- 68
PKACB           -------------------------------------------------- 68
PKACG           -------------------------------------------------- 68
PRKX            -------------------------------------------------- 68
PRKY            -------------------------------------------------- 68
PKCA            -------------------------------------------------- 69
PKCB            -------------------------------------------------- 69
PKCG            -------------------------------------------------- 74
PKCE            -------------------------------------------------- 69
PKCH            -------------------------------------------------- 69
PKCD            -------------------------------------------------- 69
PKCT            -------------------------------------------------- 69
PKCI            -------------------------------------------------- 69
PKCZ            -------------------------------------------------- 69
PKN1            -------------------------------------------------- 71
PKN2            -------------------------------------------------- 71
PKN3            -------------------------------------------------- 71
SGK             -------------------------------------------------- 69
SGK2            -------------------------------------------------- 69
SGK3            -------------------------------------------------- 69
PKG1            -------------------------------------------------- 69
PKG2            -------------------------------------------------- 68
AURB            -------------------------------------------------- 69
AURC            -------------------------------------------------- 69
AURA            -------------------------------------------------- 69
AURORA2_AVE     -------------------------------------------------- 69
PLK1            -------------------------------------------------- 69
PLK2            -------------------------------------------------- 69
PLK3            -------------------------------------------------- 69
PLK4            -------------------------------------------------- 69
NEK11           -------------------------------------------------- 71
YANK1           -------------------------------------------------- 68
YANK2           -------------------------------------------------- 68
YANK3           -------------------------------------------------- 68
SGK494          -------------------------------------------------- 68
DOMAIN2_MSK1    -------------------------------------------------- 66
DOMAIN2_MSK2    -------------------------------------------------- 60
DOMAIN2_RSK1    -------------------------------------------------- 65
DOMAIN2_RSK2    -------------------------------------------------- 65
DOMAIN2_RSK3    -------------------------------------------------- 65
DOMAIN2_RSK4    -------------------------------------------------- 65
DRAK1           -------------------------------------------------- 71
DRAK2           -------------------------------------------------- 71
1JKSA           -------------------------------------------------- 74
DAPK1           -------------------------------------------------- 74
DAPK3           -------------------------------------------------- 74
DAPK2           -------------------------------------------------- 74
SGK085          -------------------------------------------------- 68
CAMLCK          -------------------------------------------------- 68
SKMLCK          -------------------------------------------------- 68
SMMLCK          -------------------------------------------------- 68
1KOBA           -------------------------------------------------- 68
1TKIA           -------------------------------------------------- 67
TTN             -------------------------------------------------- 67
PKD1            -------------------------------------------------- 70
PKD3            -------------------------------------------------- 70
PKD2            -------------------------------------------------- 70
PSKH1           -------------------------------------------------- 68
PSKH2           -------------------------------------------------- 68
CAMK1A          -------------------------------------------------- 69
CAMK1D          -------------------------------------------------- 69
CAMK1B          -------------------------------------------------- 69
CAMK1G          -------------------------------------------------- 68
CAMK4           -------------------------------------------------- 66
DCAMKL1         -------------------------------------------------- 69
DCAMKL2         -------------------------------------------------- 69
DCAMKL3         -------------------------------------------------- 69
CHK2            -------------------------------------------------- 76
MAPKAPK2        -------------------------------------------------- 65
MAPKAPK3        -------------------------------------------------- 65
MAPKAPK5        -------------------------------------------------- 65
MNK1            -------------------------------------------------- 70
MNK2            -------------------------------------------------- 69
VACAMKL         -------------------------------------------------- 69
GCK             -------------------------------------------------- 66
KHS1            -------------------------------------------------- 66
KHS2            -------------------------------------------------- 66
HPK1            -------------------------------------------------- 66
MST1            -------------------------------------------------- 64
MST2            -------------------------------------------------- 64
MST3            -------------------------------------------------- 67
YSK1            -------------------------------------------------- 67
MST4            -------------------------------------------------- 67
LOK             -------------------------------------------------- 66
SLK             -------------------------------------------------- 66
MAP3K4          -------------------------------------------------- 68
MAP3K2          -------------------------------------------------- 71
MAP3K3          -------------------------------------------------- 71
MAP3K8          -------------------------------------------------- 71
MAP3K5          -------------------------------------------------- 71
MAP3K7          -------------------------------------------------- 64
MAP3K6          -------------------------------------------------- 61
PAK1            -------------------------------------------------- 66
PAK3            -------------------------------------------------- 66
PAK2            -------------------------------------------------- 66
PAK4            -------------------------------------------------- 66
PAK5            -------------------------------------------------- 66
PAK6            -------------------------------------------------- 66
OSR1            -------------------------------------------------- 67
STLK3           -------------------------------------------------- 67
TAO1            -------------------------------------------------- 69
TAO3            -------------------------------------------------- 69
TAO2            -------------------------------------------------- 69
MYO3A           -------------------------------------------------- 66
MYO3B           -------------------------------------------------- 66
ZC1/HGK         -------------------------------------------------- 66
ZC3/MINK        -------------------------------------------------- 66
ZC2/TNIK        -------------------------------------------------- 66
ZC4/NRK         -------------------------------------------------- 90
MAP3K1          -------------------------------------------------- 72
GAK             -------------------------------------------------- 73
SGK495          -------------------------------------------------- 0
TRB1            -------------------------------------------------- 52
TRB2            -------------------------------------------------- 57
TRB3            -------------------------------------------------- 55
SSTK            -------------------------------------------------- 68
TSSK3           -------------------------------------------------- 68
TSSK1           -------------------------------------------------- 68
TSSK2           -------------------------------------------------- 68
TSSK4           -------------------------------------------------- 68
HUNK            -------------------------------------------------- 70
SNRK            -------------------------------------------------- 67
NIM1            -------------------------------------------------- 67
MELK            -------------------------------------------------- 66
BRSK1           -------------------------------------------------- 67
BRSK2           -------------------------------------------------- 67
MARK1           -------------------------------------------------- 67
MARK2           -------------------------------------------------- 67
MARK3           -------------------------------------------------- 67
MARK4           -------------------------------------------------- 67
QIK             -------------------------------------------------- 67
SIK             -------------------------------------------------- 67
QSK             -------------------------------------------------- 67
AMPKA1          -------------------------------------------------- 68
AMPKA2          -------------------------------------------------- 68
NUAK1           -------------------------------------------------- 68
NUAK2           -------------------------------------------------- 67
BIKE            -------------------------------------------------- 70
AAK1            -------------------------------------------------- 70
LIMK1           -------------------------------------------------- 67
LIMK2           -------------------------------------------------- 67
TESK1           -------------------------------------------------- 65
TESK2           -------------------------------------------------- 55
WNK1            -------------------------------------------------- 71
WNK3            -------------------------------------------------- 71
WNK2            -------------------------------------------------- 71
WNK4            -------------------------------------------------- 71
NEK10           -------------------------------------------------- 78
NEK6            -------------------------------------------------- 70
NEK7            -------------------------------------------------- 70
NEK2            -------------------------------------------------- 69
NEK1            -------------------------------------------------- 69
NEK5            -------------------------------------------------- 69
NEK3            -------------------------------------------------- 68
NEK4            -------------------------------------------------- 69
NEK8            -------------------------------------------------- 69
NEK9            -------------------------------------------------- 69
NRBP1           -------------------------------------------------- 76
NRBP2           -------------------------------------------------- 76
CLIK1           -------------------------------------------------- 74
CLIK1L          -------------------------------------------------- 74
STK33           -------------------------------------------------- 67
DOMAIN2_GCN2    -------------------------------------------------- 78
SCYL1           -------------------------------------------------- 47
SCYL3           -------------------------------------------------- 40
DOMAIN2_JAK1    -------------------------------------------------- 67
DOMAIN2_TYK2    -------------------------------------------------- 81
DOMAIN2_JAK2    -------------------------------------------------- 64
DOMAIN2_JAK3    -------------------------------------------------- 63
ILK             -------------------------------------------------- 57
LRRK1           -------------------------------------------------- 77
PBK             -------------------------------------------------- 65
WEE1            -------------------------------------------------- 60
WEE1B           -------------------------------------------------- 60
SGK071          -------------------------------------------------- 57
PIK3R4          -------------------------------------------------- 50
MSSK1           -------------------------------------------------- 71
SRPK1           -------------------------------------------------- 71
SRPK2           -------------------------------------------------- 71
RSKL1           ------------------------------------------TKGESGLV 54
RSKL2           ------------------------------------------TSGSSDLP 167
SGK396          ------------------------------------------AEGDSGLL 59
VRK1            -------------------------------------------------- 73
VRK2            -------------------------------------------------- 71
VRK3            -------------------------------------------------- 32
BUB1            -------------------------------------------------- 62
BUBR1           -------------------------------------------------- 69
SGK196          -------------------------------------------------- 53
SGK493          -------------------------------------------------- 70
                                                                  

DYRK1A          -----K--------------------------------------RH--FM 71
DYRK1B          -----K--------------------------------------RH--FM 71
DYRK2           -----L--------------------------------------EN--FT 71
DYRK3           -----L--------------------------------------ES--FT 71
DYRK4           -----K--------------------------------------DF--FY 71
HIPK1           -----Y--------------------------------------EC--FQ 70
HIPK2           -----Y--------------------------------------EC--FQ 70
HIPK3           -----Y--------------------------------------EC--FQ 70
HIPK4           -----L--------------------------------------EF--FH 70
PRP4            -----F--------------------------------------RH--FY 72
MOK             -----H--------------------------------------EVVFDR 70
1A6O            -----L--------------------------------------DIVRDQ 66
1LPUA           -----L--------------------------------------DIVRDQ 66
CK2A1           -----A--------------------------------------DIVKDP 66
CK2A1-RS        -----A--------------------------------------DIVKDP 66
CK2A2           -----I--------------------------------------DTVKDP 66
HSER            ------------------------------DYYNLTKFY-----GTVK-- 64
SLOB            -----T--------------------------------------FATA-- 69
CDC7            -----K--------------------------------------YCF--R 68
1CSN            -----Y--------------------------------------YFG--Q 65
CK1G1           -----Y--------------------------------------YFG--P 66
CK1G3           -----Y--------------------------------------YFG--P 65
CK1G2           -----Y--------------------------------------YFG--P 65
CK1A            -----R--------------------------------------WYG--Q 65
CK1A2           -----H--------------------------------------WYG--Q 65
1CKJA           -----R--------------------------------------WCG--A 65
CK1D            -----R--------------------------------------WCG--A 65
CK1E            -----K--------------------------------------WCG--A 65
TTBK1           -----I--------------------------------------GCG--R 65
TTBK2           -----I--------------------------------------GCG--R 65
TLK1            -----Y--------------------------------------DYFS-L 74
TLK2            -----Y--------------------------------------DYFS-L 74
GPRK4           -----A--------------------------------------YAYE-- 69
GPRK6           -----A--------------------------------------YAYE-- 69
GPRK5           -----A--------------------------------------YAYE-- 69
RHOK            -----A--------------------------------------YAFE-- 69
GPRK7           -----A--------------------------------------YAFE-- 69
BARK1           -----S--------------------------------------YAFH-- 72
BARK2           -----T--------------------------------------YAFH-- 72
TTK             -----Y--------------------------------------DYE--I 69
RIPK1           -----L--------------------------------------GVII-- 67
HASPIN          -----TEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFK-D 113
GCN2            --------------------------SEPSVTTEAVH------------- 207
HRI             --------------------------GQTEAQYH---------------- 211
KIS             ----------LDVSVSE--------------------------------- 98
PDK1            -------------------------------------------------- 73
PKR             ----------YDPENSKNSSRSKTK------------------------- 94
PEK             GNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSS 287
PRPK            -------------------------------------------------- 77
DOMAIN2_OBSCN   -------------------------------------------------- 66
DOMAIN2_SPEG    -------------------------------------------------- 66
LMR1            -------------------------------------------------- 70
LMR2            -------------------------------------------------- 70
LMR3            -------------------------------------------------- 70
SGK307          -------------------------------------------------- 6
STLK5           -------------------------------------------------- 71
STLK6           -------------------------------------------------- 71
STLK6-RS        -------------------------------------------------- 71
OBSCN           -------------------------------------------------- 66
SPEG            -------------------------------------------------- 66
TRAD            -------------------------------------------------- 66
TRIO            -------------------------------------------------- 66
SGK223          -------------------------------------------------- 67
SGK269          -------------------------------------------------- 70
ALK1            -----------------------------------------------RNS 68
ALK2            -----------------------------------------------RHS 68
IRAK4           -----------------------------------------------D-- 71
BMPR2           -----------------------------------------------TAD 68
TGFBR2          -----------------------------------------------TEL 74
ACTR2           -----------------------------------------------TSV 68
ACTR2B          -----------------------------------------------SNL 68
1B6CB           -----------------------------------------------NGT 68
TGFBR1          -----------------------------------------------NGT 68
ALK4            -----------------------------------------------NGT 68
ALK7            -----------------------------------------------NGT 68
BMPR1A          -----------------------------------------------TGS 68
BMPR1B          -----------------------------------------------TGS 68
IRAK1           -----------------------------------------------GF- 72
IRAK2           ------------------------------------------------S- 74
IRAK3           ------------------------------------------------C- 74
MISR2           -------------------------------------------------L 69
MYT1            ------------------------------------------------Y- 75
SBK             ------------------------------------------------YV 73
SGK110          ------------------------------------------------FA 73
SGK069          ------------------------------------------------YS 73
SGK496          ------------------------------------------------GG 74
NIK             ------------------------------------------------N- 67
SGK424          -------------------------------------------------- 0
SURTK106        ------------------------------------------------Y- 78
IKKE            -------------------------------------------------- 72
TBK1            -------------------------------------------------- 72
MOS             -------------------------------------------------- 71
LKB1            -------------------------------------------------- 75
CAMKK1          -------------------------------------------------- 106
CAMKK2          -------------------------------------------------- 97
PASK            -------------------------------------------------- 79
PIM1            -------------------------------------------------- 79
PIM3            -------------------------------------------------- 80
PIM2            -------------------------------------------------- 81
COT             -------------------------------------------------- 68
SCYL2           -------------------------------------------------- 83
FUSED           ---------------------------------------------FETDK 71
ULK1            ---------------------------------------------QEMAN 71
ULK2            ---------------------------------------------QELPN 71
ULK3            ---------------------------------------------QWDSD 72
ULK4            ---------------------------------------------YETSN 66
IRE1            ---------------------------------------------EKDRQ 66
IRE2            ---------------------------------------------ERGPQ 66
RNASEL          ---------------------------------------------ESHRG 60
MPSK1           ---------------------------------------------ERGAK 72
PINK1           ------------------------------GALVDYPDVLPSRLHPEGLG 154
ALK             -------------------------------------------------- 73
LTK             -------------------------------------------------- 73
ROS             -------------------------------------------------- 74
IGF1R           -------------------------------------------------- 73
1IR3A           -------------------------------------------------- 73
INSR            -------------------------------------------------- 73
IRR             -------------------------------------------------- 73
1M14A           -------------------------------------------------- 72
EGFR            -------------------------------------------------- 72
HER2/ERBB2      -------------------------------------------------- 72
HER4/ERBB4      -------------------------------------------------- 72
HER3/ERBB3      -------------------------------------------------- 72
ITK             -------------------------------------------------- 65
TEC             -------------------------------------------------- 65
TXK             -------------------------------------------------- 65
BMX             -------------------------------------------------- 65
1K2PA           -------------------------------------------------- 65
BTK             -------------------------------------------------- 65
CCK4            -------------------------------------------------- 72
ROR1            -------------------------------------------------- 72
ROR2            -------------------------------------------------- 73
MUSK            -------------------------------------------------- 73
TRKA            -------------------------------------------------- 72
TRKB            -------------------------------------------------- 72
TRKC            -------------------------------------------------- 72
DDR1            -------------------------------------------------- 84
DDR2            -------------------------------------------------- 84
RYK             -------------------------------------------------- 73
JAK1            -------------------------------------------------- 72
JAK2            -------------------------------------------------- 72
JAK3            -------------------------------------------------- 72
ACK             -------------------------------------------------- 74
TYK2            -------------------------------------------------- 73
TNK1            -------------------------------------------------- 75
EPHA1           -------------------------------------------------- 71
EPHA10          -------------------------------------------------- 71
FAK             -------------------------------------------------- 71
EPHB6           -------------------------------------------------- 71
EPHA2           -------------------------------------------------- 72
EPHA8           -------------------------------------------------- 71
EPHA6           ---------------GVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIP 112
EPHB1           -------------------------------------------------- 71
EPHB2           -------------------------------------------------- 71
EPHB3           -------------------------------------------------- 71
EPHB4           -------------------------------------------------- 71
EPHA7           -------------------------------------------------- 71
EPHA4           -------------------------------------------------- 71
EPHA3           -------------------------------------------------- 71
EPHA5           -------------------------------------------------- 71
PYK2            -------------------------------------------------- 71
CSK             -------------------------------------------------- 63
CTK             -------------------------------------------------- 63
1IEPA           -------------------------------------------------- 66
ABL             -------------------------------------------------- 66
ARG             -------------------------------------------------- 66
BRK             -------------------------------------------------- 67
SRM             -------------------------------------------------- 66
FRK             -------------------------------------------------- 66
FGR             -------------------------------------------------- 65
FYN             -------------------------------------------------- 65
SRC             -------------------------------------------------- 65
YES             -------------------------------------------------- 65
HCK             -------------------------------------------------- 65
LYN             -------------------------------------------------- 66
3LCK            -------------------------------------------------- 65
LCK             -------------------------------------------------- 65
BLK             -------------------------------------------------- 65
FER             -------------------------------------------------- 68
FES             -------------------------------------------------- 69
SYK             -------------------------------------------------- 72
ZAP70           -------------------------------------------------- 71
FGFR1           -------------------------------------------------- 78
FGFR2           -------------------------------------------------- 78
FGFR3           -------------------------------------------------- 78
FGFR4           -------------------------------------------------- 78
RET             -------------------------------------------------- 75
TIE1            -------------------------------------------------- 73
1FVRA           -------------------------------------------------- 73
TIE2            -------------------------------------------------- 73
FLT1            -------------------------------------------------- 77
KDR             -------------------------------------------------- 77
KDR_AVE         -------------------------------------------------- 77
FLT4            -------------------------------------------------- 77
FMS             -------------------------------------------------- 76
FLT3            -------------------------------------------------- 76
KIT             -------------------------------------------------- 76
PDGFRA          -------------------------------------------------- 76
PDGFRB          -------------------------------------------------- 76
MER             -------------------------------------------------- 76
AXL             -------------------------------------------------E 76
TYRO3           -------------------------------------------------G 77
MET             -------------------------------------------------- 74
RON             -------------------------------------------------- 74
HH498           -------------------------------------------------- 68
LZK             -------------------------------------------------T 57
DLK             -------------------------------------------------T 57
MLK1            -------------------------------------------------L 68
MLK3            -------------------------------------------------L 68
MLK2            -------------------------------------------------L 68
MLK4            -------------------------------------------------L 68
ZAK             -------------------------------------------------L 58
TAK1            -------------------------------------------------L 62
KSR1            -------------------------------------------------M 65
KSR2            -------------------------------------------------M 65
ARAF            -------------------------------------------------- 66
RAF1            -------------------------------------------------- 66
BRAF            -------------------------------------------------T 65
LRRK2           -------------------------------------------------I 62
ANKRD3          -------------------------------------------------R 68
SGK288          -------------------------------------------------K 67
RIPK2           -------------------------------------------------N 69
RIPK3           -----------------------------------------------WDQ 66
MLKL            -------------------------------------------------- 68
ANPA            -------------------------------------------------T 69
ANPB            -------------------------------------------------I 69
CYGD            ---------------------------------------------GPAAL 78
CYGF            -------------------------------------------------Y 83
TBCK            -------------------------------------------------- 46
ERK1            ------------------------------------------------LE 72
3ERK            ------------------------------------------------IE 72
ERK2            ------------------------------------------------IE 72
ERK5            ------------------------------------------------YG 74
1JNK            ------------------------------------------------LE 74
1PMNA           ------------------------------------------------LE 74
JNK3            ------------------------------------------------LE 74
JNK1            ------------------------------------------------LE 74
JNK2            ------------------------------------------------LE 74
1P38            ------------------------------------------------LE 74
P38A            ------------------------------------------------LE 74
P38B            ------------------------------------------------IE 74
P38D            ------------------------------------------------LR 74
P38G            ------------------------------------------------LD 74
NLK             ------------------------------------------------ID 73
ERK7            -------------------------------------------------- 90
ERK3            -------------------------------------------DDVGSLT 80
ERK4            --------------------------------------------LQGELF 77
ICK             -------------------------------------------------- 70
MAK             -------------------------------------------------- 70
PCTAIRE1        -------------------------------------------------- 70
PCTAIRE2        -------------------------------------------------- 70
PCTAIRE3        -------------------------------------------------- 70
PFTAIRE1        -------------------------------------------------- 70
PFTAIRE2        -------------------------------------------------- 70
CDC2            -------------------------------------------------- 71
1HCL            -------------------------------------------------- 67
CDK2            -------------------------------------------------- 71
CDK3            -------------------------------------------------- 71
CDK5            -------------------------------------------------- 71
CDK7            -------------------------------------------------- 74
CDK4            --------------------------------------------REI--- 82
1BLXA           --------------------------------------------RET--- 80
CDK6            --------------------------------------------RET--- 80
PITSLRE         -------------------------------------------------- 71
CDK10           -------------------------------------------------- 71
CDK9            --------------------------------------------YNR--- 76
CHED            --------------------------------------------LDFK-K 78
CRK7            --------------------------------------------LDFK-K 78
CCRK            -------------------------------------------------- 72
CDK11           -------------------------------------------------- 71
CDK8            -------------------------------------------------- 71
IKKA            --------------------------------------------EL-NIL 72
IKKB            --------------------------------------------GMQNLA 73
1PHK            -------------------------------------------------- 76
PHKG1           -------------------------------------------------- 76
PHKG2           -------------------------------------------------- 75
CAMK2A          -------------------------------------------------- 68
CAMK2B          -------------------------------------------------- 68
CAMK2G          -------------------------------------------------- 68
CAMK2D          -------------------------------------------------- 68
CASK            -------------------------------------------------- 71
1IA8A           -------------------------------------------------- 64
CHK1            -------------------------------------------------- 67
CLK1            -------------------------------------------------- 72
CLK4            -------------------------------------------------- 71
CLK2            -------------------------------------------------- 72
CLK3            -------------------------------------------------- 72
MAP2K5          -------------------------------------------------- 67
MAP2K3          -------------------------------------------------- 68
MAP2K6          -------------------------------------------------- 68
MAP2K4          -------------------------------------------------- 68
MAP2K7          -------------------------------------------------- 68
MAP2K1          -------------------------------------------------- 67
MAP2K2          -------------------------------------------------- 67
CDKL5           -------------------------------------------------- 68
CDKL1           -------------------------------------------------- 68
CDKL4           -------------------------------------------------- 68
CDKL2           -------------------------------------------------- 68
CDKL3           -------------------------------------------------- 67
1I09B           -------------------------------------------------K 68
GSK3B           -------------------------------------------------K 68
1J1BA           -------------------------------------------------K 68
GSK3A           -------------------------------------------------K 68
LATS1           -------------------------------------------------Q 69
LATS2           -------------------------------------------------Q 69
NDR1            -------------------------------------------------Q 69
NDR2            -------------------------------------------------Q 69
MAST1           -------------------------------------------------E 69
MAST4           -------------------------------------------------E 69
MAST2           -------------------------------------------------D 69
MAST3           -------------------------------------------------E 69
MRCKA           -------------------------------------------------Q 69
MRCKB           -------------------------------------------------Q 69
DMPK2           -------------------------------------------------Q 69
DMPK1           -------------------------------------------------Q 69
ROCK1           -------------------------------------------------Q 69
ROCK2           -------------------------------------------------Q 69
CRIK            -------------------------------------------------Q 69
MASTL           -------------------------------------------------Q 67
1O6LA           -------------------------------------------------Q 69
AKT2            -------------------------------------------------Q 69
AKT1            -------------------------------------------------Q 69
AKT3            -------------------------------------------------Q 69
MSK1            -------------------------------------------------Q 74
MSK2            -------------------------------------------------Q 74
P70S6K          -------------------------------------------------Q 73
P70S6KB         -------------------------------------------------Q 73
RSK1            -------------------------------------------------Q 71
RSK3            -------------------------------------------------Q 71
RSK2            -------------------------------------------------Q 71
RSK4            -------------------------------------------------Q 71
1FOTA           -------------------------------------------------Q 69
1CDKA           -------------------------------------------------K 69
PKACA           -------------------------------------------------K 69
PKACB           -------------------------------------------------K 69
PKACG           -------------------------------------------------K 69
PRKX            -------------------------------------------------H 69
PRKY            -------------------------------------------------H 69
PKCA            -------------------------------------------------Q 70
PKCB            -------------------------------------------------Q 70
PKCG            -------------------------------------------------Q 75
PKCE            -------------------------------------------------Q 70
PKCH            -------------------------------------------------Q 70
PKCD            -------------------------------------------------Q 70
PKCT            -------------------------------------------------Q 70
PKCI            -------------------------------------------------Q 70
PKCZ            -------------------------------------------------Q 70
PKN1            -------------------------------------------------Q 72
PKN2            -------------------------------------------------Q 72
PKN3            -------------------------------------------------Q 72
SGK             -------------------------------------------------Q 70
SGK2            -------------------------------------------------Q 70
SGK3            -------------------------------------------------Q 70
PKG1            -------------------------------------------------K 70
PKG2            -------------------------------------------------K 69
AURB            -------------------------------------------------- 69
AURC            -------------------------------------------------- 69
AURA            -------------------------------------------------- 69
AURORA2_AVE     -------------------------------------------------- 69
PLK1            -------------------------------------------------- 69
PLK2            -------------------------------------------------- 69
PLK3            -------------------------------------------------- 69
PLK4            -------------------------------------------------- 69
NEK11           -------------------------------------------------- 71
YANK1           -------------------------------------------------Q 69
YANK2           -------------------------------------------------Q 69
YANK3           -------------------------------------------------Q 69
SGK494          -------------------------------------------------Q 69
DOMAIN2_MSK1    -------------------------------------------------- 66
DOMAIN2_MSK2    -------------------------------------------------- 60
DOMAIN2_RSK1    -------------------------------------------------- 65
DOMAIN2_RSK2    -------------------------------------------------- 65
DOMAIN2_RSK3    -------------------------------------------------- 65
DOMAIN2_RSK4    -------------------------------------------------- 65
DRAK1           -------------------------------------------------- 71
DRAK2           -------------------------------------------------- 71
1JKSA           -------------------------------------------------- 74
DAPK1           -------------------------------------------------- 74
DAPK3           -------------------------------------------------- 74
DAPK2           -------------------------------------------------- 74
SGK085          -------------------------------------------------- 68
CAMLCK          -------------------------------------------------- 68
SKMLCK          -------------------------------------------------- 68
SMMLCK          -------------------------------------------------- 68
1KOBA           -------------------------------------------------- 68
1TKIA           -------------------------------------------------- 67
TTN             -------------------------------------------------- 67
PKD1            -------------------------------------------------- 70
PKD3            -------------------------------------------------- 70
PKD2            -------------------------------------------------- 70
PSKH1           -------------------------------------------------- 68
PSKH2           -------------------------------------------------- 68
CAMK1A          -------------------------------------------------- 69
CAMK1D          -------------------------------------------------- 69
CAMK1B          -------------------------------------------------- 69
CAMK1G          -------------------------------------------------- 68
CAMK4           -------------------------------------------------- 66
DCAMKL1         -------------------------------------------------- 69
DCAMKL2         -------------------------------------------------- 69
DCAMKL3         -------------------------------------------------- 69
CHK2            -------------------------------------------------- 76
MAPKAPK2        -------------------------------------------A------ 66
MAPKAPK3        -------------------------------------------H------ 66
MAPKAPK5        -------------------------------------------QFPHESS 72
MNK1            -------------------------------------------------- 70
MNK2            -------------------------------------------------- 69
VACAMKL         -------------------------------------------------- 69
GCK             --------------------------------------------RN---- 68
KHS1            --------------------------------------------SR---- 68
KHS2            --------------------------------------------RR---- 68
HPK1            --------------------------------------------WL---- 68
MST1            --------------------------------------------KN---- 66
MST2            --------------------------------------------KN---- 66
MST3            --------------------------------------------KD---- 69
YSK1            --------------------------------------------KS---- 69
MST4            --------------------------------------------KG---- 69
LOK             --------------------------------------------HD---- 68
SLK             --------------------------------------------YE---- 68
MAP3K4          --------------------------------------------HR---- 70
MAP3K2          --------------------------------------------DPQ--- 74
MAP3K3          --------------------------------------------DRA--- 74
MAP3K8          --------------------------------------------QE---- 73
MAP3K5          --------------------------------------------EN---- 73
MAP3K7          --------------------------------------------EN---- 66
MAP3K6          --------------------------------------------QG---- 63
PAK1            --------------------------------------------VG---- 68
PAK3            --------------------------------------------VG---- 68
PAK2            --------------------------------------------VG---- 68
PAK4            --------------------------------------------VG---- 68
PAK5            --------------------------------------------VG---- 68
PAK6            --------------------------------------------VG---- 68
OSR1            --------------------------------------------VK---- 69
STLK3           --------------------------------------------VK---- 69
TAO1            --------------------------------------------RE---- 71
TAO3            --------------------------------------------KE---- 71
TAO2            --------------------------------------------RE---- 71
MYO3A           --------------------------------------------KKDKV- 71
MYO3B           --------------------------------------------KADHC- 71
ZC1/HGK         --------------------------------------------KKSPPG 72
ZC3/MINK        --------------------------------------------KKSPPG 72
ZC2/TNIK        --------------------------------------------KKNPPG 72
ZC4/NRK         --------------------------------------------KLSPPG 96
MAP3K1          --------------------------------------------EK---- 74
GAK             ------------------------------------------------DT 75
SGK495          -------------------------------------------------- 0
TRB1            ------------------------------------------------LG 54
TRB2            ------------------------------------------------LG 59
TRB3            ------------------------------------------------AG 57
SSTK            ------------------------------------------------EV 70
TSSK3           ------------------------------------------------ES 70
TSSK1           ------------------------------------------------ET 70
TSSK2           ------------------------------------------------ET 70
TSSK4           ------------------------------------------------ES 70
HUNK            ------------------------------------------------ET 72
SNRK            ------------------------------------------------DT 69
NIM1            ------------------------------------------------ET 69
MELK            ------------------------------------------------ET 68
BRSK1           ------------------------------------------------EN 69
BRSK2           ------------------------------------------------EN 69
MARK1           ------------------------------------------------ET 69
MARK2           ------------------------------------------------ET 69
MARK3           ------------------------------------------------ET 69
MARK4           ------------------------------------------------ET 69
QIK             ------------------------------------------------ET 69
SIK             ------------------------------------------------ET 69
QSK             ------------------------------------------------ET 69
AMPKA1          ------------------------------------------------ST 70
AMPKA2          ------------------------------------------------ST 70
NUAK1           ------------------------------------------------EN 70
NUAK2           ------------------------------------------------EN 69
BIKE            ------------------------------------------------DN 72
AAK1            ------------------------------------------------SG 72
LIMK1           -------------------------------------------------- 67
LIMK2           -------------------------------------------------- 67
TESK1           -------------------------------------------------- 65
TESK2           -------------------------------------------------- 55
WNK1            -------------------------------------------------K 72
WNK3            -------------------------------------------------K 72
WNK2            -------------------------------------------------K 72
WNK4            -------------------------------------------------R 72
NEK10           -------------------------------------------------- 78
NEK6            -------------------------------------------------- 70
NEK7            -------------------------------------------------- 70
NEK2            -------------------------------------------------R 70
NEK1            -------------------------------------------------- 69
NEK5            -------------------------------------------------- 69
NEK3            -------------------------------------------------- 68
NEK4            -------------------------------------------------- 69
NEK8            -------------------------------------------------- 69
NEK9            -------------------------------------------------- 69
NRBP1           -------------------------------------------------E 77
NRBP2           -------------------------------------------------E 77
CLIK1           -------------------QRMSHGNKSSQLYLRLVETSLKGERILGYAE 105
CLIK1L          -------------------QKMSHGSNSS-LYLQLVETSLKGE-IAFDPR 103
STK33           -------------------------------------------------E 68
DOMAIN2_GCN2    --------------------------------VVRYLAMNLKEQD----- 91
SCYL1           --------------------------------ILAYIDGLETEKC----- 60
SCYL3           --------------------------------LLRFLSCTVEADG----- 53
DOMAIN2_JAK1    --------------------------------IVYLYGVCVRDV------ 79
DOMAIN2_TYK2    --------------------------------LAFVHGVCVRGP------ 93
DOMAIN2_JAK2    --------------------------------LVLNYGVCVCGD------ 76
DOMAIN2_JAK3    --------------------------------LVLLHGVCMAGD------ 75
ILK             --------------------------------VLPVLGACQSPPA----P 71
LRRK1           --------------------------------IVALIGISIH-------- 87
PBK             --------------------------------IVGYRAFTEASD-----G 78
WEE1            --------------------------------VVRYFSAWAEDD------ 72
WEE1B           --------------------------------VVRYYSSWAEDD------ 72
SGK071          --------------------------------ISVYQELFITWNGEISSL 75
PIK3R4          ------------------------IRLNSAQNCLPFQKASEKASE----K 72
MSSK1           -----------------------------------------FRISGVNGV 80
SRPK1           -----------------------------------------FKISGVNGT 80
SRPK2           -----------------------------------------FKISGMNGI 80
RSKL1           LEGDKEIHQIFEDLDKKLAL------------------------------ 74
RSKL2           KAPGGHLHLQARRAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMD----- 212
SGK396          --------------------------------PLIFLFLCKSDP------ 71
VRK1            --------------------------------VPKYWGSGLHD--KNGKS 89
VRK2            --------------------------------IPLFYGSGLTE--FKGRS 87
VRK3            -------------------------------------------------K 33
BUB1            --------------------------------FMKFYSAHLFQN------ 74
BUBR1           -----------------------------------FCSCYQYQD------ 78
SGK196          --------------------------------VVTLLGYCEDD------- 64
SGK493          --------------------------------VLQLYGYCYQDSE----D 84
                                                                  

DYRK1A          FRNHLCLVFEMLSYNLYD-LLRNTN------------------------- 95
DYRK1B          FRNHLCLVFELLSYNLYD-LLRNTH------------------------- 95
DYRK2           FRNHICMTFELLSMNLYE-LIKKNK------------------------- 95
DYRK3           FRNHVCMAFELLSIDLYE-LIKKNK------------------------- 95
DYRK4           FRNHFCITFELLGINLYE-LMKNNN------------------------- 95
HIPK1           HKNHTCLVFEMLEQNLYD-FLKQNK------------------------- 94
HIPK2           HKNHTCLVFEMLEQNLYD-FLKQNK------------------------- 94
HIPK3           HRNHTCLVFEMLEQNLYD-FLKQNK------------------------- 94
HIPK4           DALKFYLVFELLEQNLFE-FQKENN------------------------- 94
PRP4            HKQHLCLVFEPLSMNLRE-VLKKYG------------------------- 96
MOK             KSGSLALICELMDMNIYE-LIRGRR------------------------- 94
1A6O            HSKTPSLIFEYVNNTDFK-VL----------------------------- 86
1LPUA           HSKTPSLIFEYVNNTDFK-VL----------------------------- 86
CK2A1           VSRTPALVFEHVNNTDFK-QL----------------------------- 86
CK2A1-RS        VSRTPALVFEHVNNTDFK-QL----------------------------- 86
CK2A2           VSKTPALVFEYINNTDFK-QL----------------------------- 86
HSER            LDTMIFGVIEYCERGSLREVLNDTISYP---------------------- 92
SLOB            NESSALLIRMFNEKGTLKDLIYKAKPKD---------------------- 97
CDC7            KNDHVVIAMPYLEHESFLDI------------------------------ 88
1CSN            EGLHNVLVIDLLGPSL-EDLLDLCG------------------------- 89
CK1G1           CGKYNAMVLELLGPSL-EDLFDLCD------------------------- 90
CK1G3           CGKYNAMVLELLGPSL-EDLFDLCD------------------------- 89
CK1G2           CGKYNAMVLELLGPSL-EDLFDLCD------------------------- 89
CK1A            EKDYNVLVMDLLGPSL-EDLFNFCS------------------------- 89
CK1A2           EKDNNVLVMDLLGPSL-EDLFNFCS------------------------- 89
1CKJA           EGDYNVMVMELLGPSL-EDLFNFCS------------------------- 89
CK1D            EGDYNVMVMELLGPSL-EDLFNFCS------------------------- 89
CK1E            EGDYNVMVMELLGPSL-EDLFNFCS------------------------- 89
TTBK1           NEKFNYVVMQLQGRNL-ADLRRSQP------------------------- 89
TTBK2           NDRFNYVVMQLQGRNL-ADLRRSQS------------------------- 89
TLK1            DTDTFCTVLEYCEGNDLDFYLKQH-------------------------- 98
TLK2            DTDSFCTVLEYCEGNDLDFYLKQH-------------------------- 98
GPRK4           TKDALCLVLTIMNGGDLKFHIYNLG------------------------- 94
GPRK6           TKDALCLVLTLMNGGDLKFHIYHMG------------------------- 94
GPRK5           TKDALCLVLTIMNGGDLKFHIYNMG------------------------- 94
RHOK            TKADLCLVMTIMNGGDIRYHIYNVN------------------------- 94
GPRK7           SKTHLCLVMSLMNGGDLKFHIYNVG------------------------- 94
BARK1           TPDKLSFILDLMNGGDLHYHLSQH-------------------------- 96
BARK2           TPDKLCFILDLMNGGDLHYHLSQH-------------------------- 96
TTK             TDQYIYMVMECGNIDLN-SWLKKK-------------------------- 92
RIPK1           EEGKYSLVMEYMEKGNLMHVLKAEMS------------------------ 93
HASPIN          DQLFIVLEFEFGGIDLE-QMRTKLS------------------------- 137
GCN2            ---YLYIQMEYCEKSTLRDTI----DQGLY-------------------- 230
HRI             --LMLHIQMQLCELSLWDWIVERNKRGREYVDE----------------- 242
KIS             --LLLYSSHQGC-------------------------------------- 108
PDK1            ----LYFGLSYAKNGELLKYI----RKIGS-------------------- 95
PKR             ---CLFIQMEFCDKGTLEQWI----EKR-RGEK----------------- 119
PEK             PKVYLYIQMQLCRKENLKDWM----NGRCTIEE----------------- 316
PRPK            ---CLYME-EIEGSVTVRDYI----QSTME--T----------------- 100
DOMAIN2_OBSCN   -PRHLVLILELCSGPELLPCLAERA------------------------- 90
DOMAIN2_SPEG    -PRYLVLIAESCGNRELLCGLSDRF------------------------- 90
LMR1            -VTPYLLVMEFCPLGDLKGYLRSCRVAESM-------------------- 99
LMR2            -AIPYLLVFEFCDLGDLKAYLRSEQ------------------------- 94
LMR3            -TLPFLLIMEFCQLGDLKRYLRAQRPPEGL-------------------- 99
SGK307          -------------------------------------------------- 6
STLK5           -DNELWVVTSFMAYGSAKDLICTHFM------------------------ 96
STLK6           -GSWLWVISPFMAYGSASQLLRTYFP------------------------ 96
STLK6-RS        -GSWLWVISPFMAYGSASQLLRTCFP------------------------ 96
OBSCN           -RKTLILILELCSSEELLDRLYRKG------------------------- 90
SPEG            -RRGLVIVTELCTE-ELLERIARKP------------------------- 89
TRAD            -PTSYILILELMDDGRLLDYLMNHD------------------------- 90
TRIO            -PTSYILVLEMADQGRLLDCVVRWG------------------------- 90
SGK223          -QDCVVVITREVPHQTASDFVRDSAASHQA-------------------- 96
SGK269          -RSHVVVITREVPCLTVADFVRDSLAQHGK-------------------- 99
ALK1            S-TQLWLITHYHEHGSLYDFLQR--------------------------- 90
ALK2            S-TQLWLITHYHEMGSLYDYLQL--------------------------- 90
IRAK4           ---DLCLVYVYMPNGSLLDRLSC-LDGT---------------------- 95
BMPR2           GRMEYLLVMEYYPNGSLCKYLSL--------------------------- 91
TGFBR2          G-KQYWLITAFHAKGNLQEYLTR--------------------------- 96
ACTR2           D-VDLWLITAFHEKGSLSDFLKA--------------------------- 90
ACTR2B          E-VELWLITAFHDKGSLTDYLKG--------------------------- 90
1B6CB           W-TQLWLVSDYHEHGSLFDYLNR--------------------------- 90
TGFBR1          W-TQLWLVSDYHEHGSLFDYLNR--------------------------- 90
ALK4            W-TQLWLVSDYHEHGSLFDYLNR--------------------------- 90
ALK7            W-TQLWLVSEYHEQGSLYDYLNR--------------------------- 90
BMPR1A          W-TQLYLITDYHENGSLYDFLKC--------------------------- 90
BMPR1B          W-TQLYLITDYHENGSLYDYLKS--------------------------- 90
IRAK1           ----YCLVYGFLPNGSLEDRLHCQTQAC---------------------- 96
IRAK2           ------FIYPYMANGSL--------QDRLQ-------------------- 90
IRAK3           ------LIYPYMRNGTL--------FDRLQ-------------------- 90
MISR2           LSG-PLLVLELHPKGSL--------CHYLT-------------------- 90
MYT1            ------LQTELC-GPSL--------QQHCE-------------------- 90
SBK             ------FAQEYAPAGDL--------FDIIP-------------------- 89
SGK110          ------FAQEYAPCGDL--------SGMLQ-------------------- 89
SGK069          ------FLTEPVLHGDL--------MAFIQ-------------------- 89
SGK496          SSIAVLLIMERLHRDLY--------------------------------- 91
NIK             ------IFMELLEGGSL--------GQLVK-------------------- 83
SGK424          -------------------------------------------------- 0
SURTK106        ------MVLEDVAQGDLLGFLWTCRRDVMT-------------------- 102
IKKE            ---QKVLVMEYCSSGSLLSVLES--------------------------- 92
TBK1            ---HKVLIMEFCPCGSLYTVLEE--------------------------- 92
MOS             ---SNSLGTIIMEFGGNVTLHQVI-------------------------- 92
LKB1            ---KMYMVMEYCVCGM-QEMLDS--------------------------- 94
CAMKK1          ---NLYLV-DLLRKG---PVMEV--------------------------- 122
CAMKK2          ---HLYMVFELVNQG---PVMEV--------------------------- 114
PASK            ---QLVMEKH----GSGLDLFAF--------------------------- 95
PIM1            ---VLILERPEP----VQDLFDF--------------------------- 95
PIM3            ---LLVLERPEP----AQDLFDF--------------------------- 96
PIM2            ---MLVLERPLP----AQDLFDY--------------------------- 97
COT             ---HLFMEA-----GEGGSVLEK--------------------------- 83
SCYL2           ---LAFC-----TEPVFASLANVL-------------------------- 99
FUSED           E---VVVVTDYAEG-ELFQILE-DDG------------------------ 92
ULK1            S---VYLVMEYCNGGDLADYLH-AMR------------------------ 93
ULK2            S---VFLVMEYCNGGDLADYLQ-AKG------------------------ 93
ULK3            N---IYLIMEFCAGGDLSRFIH-TRR------------------------ 94
ULK4            H---LWLVXE---------------------------------------- 73
IRE1            F---QYIAIELCAA-TLQEYVE-QKD------------------------ 87
IRE2            F---HYIALELCRA-SLQEYVE-NPD------------------------ 87
RNASEL          H---LFVCVTLCEQ-TLEACLDVHRG------------------------ 82
MPSK1           HE--AWLLLPFFKRGTLWNEIE-RL------------------------- 94
PINK1           HGRTLFLVMKNYPC-TLRQYLC---------------------------- 175
ALK             S-LPRFILLELMAGGDLKSFLRETRPRPSQ-------------------- 102
LTK             A-TPRLILLELMSGGDMKSFLRHSRPHLGQ-------------------- 102
ROS             N-EPQYIILELMEGGDLLTYLRKARMATFY-------------------- 103
IGF1R           G-QPTLVIMELMTRGDLKSYLRSLRPEMEN-------------------- 102
1IR3A           G-QPTLVVMELMAHGDLKSYLRSLRPEAEN-------------------- 102
INSR            G-QPTLVVMELMAHGDLKSYLRSLRPEAEN-------------------- 102
IRR             G-QPTLVIMELMTRGDLKSHLRSLRPEAEN-------------------- 102
1M14A           S-T-VQLITQLMPFGCLLDYVREHKDN----------------------- 97
EGFR            S-T-VQLITQLMPFGCLLDYVREHKDN----------------------- 97
HER2/ERBB2      S-T-VQLVTQLMPYGCLLDHVRENRGR----------------------- 97
HER4/ERBB4      P-T-IQLVTQLMPHGCLLEYVHEHKDN----------------------- 97
HER3/ERBB3      S--SLQLVTQYLPLGSLLDHVRQHRGA----------------------- 97
ITK             Q-APICLVFEFMEHGCLSDYLRTQRGL----------------------- 91
TEC             Q-KPIYIVTEFMERGCLLNFLRQRQGH----------------------- 91
TXK             R-KPLYIVTEFMENGCLLNYLRENKGK----------------------- 91
BMX             E-YPIYIVTEYISNGCLLNYLRSHGKG----------------------- 91
1K2PA           Q-RPIFIITEYMANGCLLNYLREMRHR----------------------- 91
BTK             Q-RPIFIITEYMANGCLLNYLREMRHR----------------------- 91
CCK4            A-EPHYMVLEYVDLGDLKQFLRISKSKDEK-------------------- 101
ROR1            E-QPVCMLFEYINQGDLHEFLIMRSPHSDVG------------------- 102
ROR2            D-QPLSMIFSYCSHGDLHEFLVMRSPHSDV-------------------- 102
MUSK            G-KPMCLLFEYMAYGDLNEFLRSMSPHTVC-------------------- 102
TRKA            G-RPLLMVFEYMRHGDLNRFLRSHGPDAKL-------------------- 101
TRKB            G-DPLIMVFEYMKHGDLNKFLRAHGPDAVL-------------------- 101
TRKC            G-DPLIMVFEYMKHGDLNKFLRAHGPNAMI-------------------- 101
DDR1            D-DPLCMITDYMENGDLNQFLSAHQLEDKAA------------------- 114
DDR2            D-DPLCMITEYMENGDLNQFLSRHEPPNSS-------------------- 113
RYK             EGEKPMVILPYMNWGNLKLFLRQCKLVEAN-------------------- 103
JAK1            GGNGIKLIMEFLPSGSLKEYLPKNKN------------------------ 98
JAK2            GRRNLKLIMEYLPYGSLRDYLQKHKE------------------------ 98
JAK3            GRPELRLVMEYLPSGCLRDFLQRHRA------------------------ 98
ACK             ---PMKMVTELAPLGSLLDRLRKHQG------------------------ 97
TYK2            GEKSLQLVMEYVPLGSLRDYLPRHS------------------------- 98
TNK1            ---PLQMVMELAPLGSLHARLTAPAP------------------------ 98
EPHA1           -RKPIMIITEFMENAALDAFLRERE------------------------- 95
EPHA10          -GSTLMIVTEYMSHGALDGFLRRHE------------------------- 95
FAK             -N-PVWIIMELCTLGELRSFLQVRK------------------------- 94
EPHB6           -SRPLMVLTEFMELGPLDSFLRQRE------------------------- 95
EPHA2           -YKPMMIITEYMENGALDKFLREKD------------------------- 96
EPHA8           -GRLAMIVTEYMENGSLDTFLRTHD------------------------- 95
EPHA6           AGRPVMIVVEYMENGSLDSFLRKHD------------------------- 137
EPHB1           -SRPVMIITEFMENGALDSFLRQND------------------------- 95
EPHB2           -STPVMIITEFMENGSLDSFLRQND------------------------- 95
EPHB3           -SRPVMILTEFMENCALDSFLRLND------------------------- 95
EPHB4           -SMPVMILTEFMENGALDSFLRLND------------------------- 95
EPHA7           -GKPVMIVIEFMENGALDAFLRKHD------------------------- 95
EPHA4           -CKPVMIITEYMENGSLDAFLRKND------------------------- 95
EPHA3           -SKPVMIVTEYMENGSLDSFLRKHD------------------------- 95
EPHA5           -SKPVMIVTEYMENGSLDTFLKKND------------------------- 95
PYK2            --EPTWIIMELYPYGELGHYLERNK------------------------- 94
CSK             EKGGLYIVTEYMAKGSLVDYLRSRGR------------------------ 89
CTK             QG--LYIVMEHVSKGNLVNFLRTRGR------------------------ 87
1IEPA           EPP-FYIITEFMTYGNLLDYLRECNR------------------------ 91
ABL             EPP-FYIITEFMTYGNLLDYLRECNR------------------------ 91
ARG             EPP-FYIVTEYMPYGNLLDYLRECNR------------------------ 91
BRK             DP--VYIITELMAKGSLLELLRDSDE------------------------ 91
SRM             EP--VYIVTELMRKGNLQAFLGTPEG------------------------ 90
FRK             DP--IYIITELMRHGSLQEYLQNDTG------------------------ 90
FGR             EP--IYIVTEFMCHGSLLDFLKNPEG------------------------ 89
FYN             EP--IYIVTEYMNKGSLLDFLKDGEG------------------------ 89
SRC             EP--IYIVTEYMSKGSLLDFLKGETG------------------------ 89
YES             EP--IYIVTEFMSKGSLLDFLKEGDG------------------------ 89
HCK             EP--IYIITEFMAKGSLLDFLKSDEG------------------------ 89
LYN             EP--IYIITEYMAKGSLLDFLKSDEG------------------------ 90
3LCK            EP--IYIITEYMENGSLVDFLKTPSG------------------------ 89
LCK             EP--IYIITEYMENGSLVDFLKTPSG------------------------ 89
BLK             EP--IYIVTEYMARGCLLDFLKTDEG------------------------ 89
FER             QP--VYIIMELVSGGDFLTFLRRKK------------------------- 91
FES             QP--IYIVMELVQGGDFLTFLRT-EG------------------------ 92
SYK             ---SWMLVMEMAELGPLNKYLQQNR------------------------- 94
ZAP70           ---ALMLVMEMAGGGPLHKFLVGKR------------------------- 93
FGFR1           ---PLYVIVEYASKGNLREYLQARRPPGLEY------------------- 106
FGFR2           ---PLYVIVEYASKGNLREYLRARRPPGMEY------------------- 106
FGFR3           ---PLYVLVEYAAKGNLREFLRARRPPGLDY------------------- 106
FGFR4           ---PLYVIVECAAKGNLREFLRARRPPGPDL------------------- 106
RET             ---PLLLIVEYAKYGSLRGFLRESRKVGPGY-------LGSGG------- 108
TIE1            ---YLYIAIEYAPYGNLLDFLRKSRVLETDP------------------- 101
1FVRA           ---YLYLAIEYAPHGNLLDFLRKSRVLETDP------------------- 101
TIE2            ---YLYLAIEYAPHGNLLDFLRKSRVLETDP------------------- 101
FLT1            ---PLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEKM-EPGL 123
KDR             ---PLMVIVEFCKFGNLSTYLRSKRNEFVPY-KTKGAR-FRQGKDYVGAI 122
KDR_AVE         ---PLMVIVEFCKFGNLSTYLRSKRNEFVPY-K----------------- 106
FLT4            ---PLMVIVEFCKYGNLSNFLRAKRDAFSP-CAEKS---PEQRGRFRAMV 120
FMS             ---PVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQD-PEGGVDYKNIH 122
FLT3            ---PIYLIFEYCCYGDLLNYLRSKREKFHR-TWTEIFKEHNF--SFYPTF 120
KIT             ---PTLVITEYCCYGDLLNFLRRKRDSFIC-SKQED---HAEAALYKNLL 119
PDGFRA          ---PIYIITEYCFYGDLVNYLHKNRDSFLS-HHPEK---PKKELDIFGLN 119
PDGFRB          ---PIYIITEYCRYGDLVDYLHRNKHTFLQ-HHSDKRR-PPSAELYSNAL 121
MER             GIPKPMVILPFMKYGDLHTYLLYSRLETGP-------------------- 106
AXL             SFPAPVVILPFMKHGDLHSFLLYSRLGDQP-------------------- 106
TYRO3           RLPIPMVILPFMKHGDLHAFLLASRIGENP-------------------- 107
MET             ---SPLVVLPYMKHGDLRNFIRNET------------------------- 96
RON             ---LPHVLLPYMCHGDLLQFIRSPQ------------------------- 96
HH498           DPSQFAIVTQYISGGSLFSLLHEQK-RILD-------------------- 97
LZK             QAPCYCIIMEYCAHGQLYEVLRAGR------------------------- 82
DLK             QAPCYCILMEFCAQGQLYEVLRAGR------------------------- 82
MLK1            KEPNLCLVMEFARGGPLNRVLSGK-------------------------- 92
MLK3            EEPNLCLVMEYAAGGPLSRALAGR-------------------------- 92
MLK2            NPPHLCLVMEYARGGALSRVLAGR-------------------------- 92
MLK4            QQPHLCLVLEFARGGALNRALAAAN-AAPDPR------------------ 99
ZAK             EPPNYGIVTEYASLGSLYDYINSNRSEEMD-------------------- 88
TAK1            NP--VCLVMEYAEGGSLYNVLHGAE-PLPY-------------------- 89
KSR1            NPPHLAIITSFCKGRTLHSFVRDPK-TSLD-------------------- 94
KSR2            SPPHLAIITSLCKGRTLYSVVRDAK-IVLD-------------------- 94
ARAF            --PGFAIITQWCEGSSLYHHLHVAD-TRFD-------------------- 93
RAF1            --DNLAIVTQWCEGSSLYKHLHVQE-TKFQ-------------------- 93
BRAF            K-PQLAIVTQWCEGSSLYHHLHIIE-TKFE-------------------- 93
LRRK2           RPR--MLVMELASKGSLDRLLQQDK-ASLT-------------------- 89
ANKRD3          EP--VGLVMEYMETGSLEKLLASEP------------------------- 91
SGK288          QP--LGIVMEFMANGSLEKVLSTHS------------------------- 90
RIPK2           EPEFLGIVTEYMPNGSLNELLHRKT-EYPD-------------------- 98
RIPK3           D-PKPALVTKFMENGSLSGLLQSQC--PRP-------------------- 93
MLKL            -PPQFSIVMEYCELGTLRELLDREK--DLT-------------------- 95
ANPA            DPPNICILTEYCPRGSLQDILENES-ITLD-------------------- 98
ANPB            DPPNICIVTEYCPRGSLQDILENDS-INLD-------------------- 98
CYGD            WEGNLAVVSEHCTRGSLQDLLAQRE-IKLD-------------------- 107
CYGF            DSGMFAIVTEFCSRGSLEDILTNQD-VKLD-------------------- 112
TBCK            -HERLVVVAEHCER-SLEDLLRER-------------------------- 68
ERK1            AMRDVYIVQDLMETDLYK-------------------------------- 90
3ERK            QMKDVYIVQDLMETDLYK-------------------------------- 90
ERK2            QMKDVYIVQDLMETDLYK-------------------------------- 90
ERK5            EFKSVYVVLDLMESDLHQ-------------------------------- 92
1JNK            EFQDVYLVMELMDANLCQ-------------------------------- 92
1PMNA           EFQDVYLVMELMDANLCQ-------------------------------- 92
JNK3            EFQDVYLVMELMDANLCQ-------------------------------- 92
JNK1            EFQDVYIVMELMDANLCQ-------------------------------- 92
JNK2            EFQDVYLVMELMDANLCQ-------------------------------- 92
1P38            EFNDVYLVTHLMGADLNN-------------------------------- 92
P38A            EFNDVYLVTHLMGADLNN-------------------------------- 92
P38B            DFSEVYLVTTLMGADLNN-------------------------------- 92
P38D            NFYDFYLVMPFMQTDLQK-------------------------------- 92
P38G            DFTDFYLVMPFMGTDLGK-------------------------------- 92
NLK             YFEEIYVVTELMQSDLHK-------------------------------- 91
ERK7            NDRDIYLVFEFMDTDLNA-------------------------------- 108
ERK3            ELNSVYIVQEYMETDLAN-------------------------------- 98
ERK4            KFSVAYIVQEYMETDLAR-------------------------------- 95
ICK             ---HLYFIFEYMKENLYQ-------------------------------- 85
MAK             ---HLYFIFEYMKENLYQ-------------------------------- 85
PCTAIRE1        ---SLTLVFEYLDKDLKQ-------------------------------- 85
PCTAIRE2        ---SLTLVFEYLDKDLKQ-------------------------------- 85
PCTAIRE3        ---SLTLVFEYLDSDLKQ-------------------------------- 85
PFTAIRE1        ---TLTLVFEYVHTDLCQ-------------------------------- 85
PFTAIRE2        ---TLTFVFEYMHTDLAQ-------------------------------- 85
CDC2            ---RLYLIFEFLSMDLKK-------------------------------- 86
1HCL            ---KLYLVFEFLHQDLKK-------------------------------- 82
CDK2            ---KLYLVFEFLHQDLKK-------------------------------- 86
CDK3            ---KLYLVFEFLSQDLKK-------------------------------- 86
CDK5            ---KLTLVFEFCDQDLKK-------------------------------- 86
CDK7            ---NISLVFDFMETDLEV-------------------------------- 89
CDK4            ---KVTLVFEHVDQDLRT-------------------------------- 97
1BLXA           ---KLTLVFEHVDQDLTT-------------------------------- 95
CDK6            ---KLTLVFEHVDQDLTT-------------------------------- 95
PITSLRE         -MDKIYIVMNYVEHDLKS-------------------------------- 88
CDK10           -LESIFLVMGYCEQDLAS-------------------------------- 88
CDK9            CKGSIYLVFDFCEHDLAG-------------------------------- 94
CHED            DKGAFYLVFEYMDHDLMG-------------------------------- 96
CRK7            DKGAFYLVFEYMDHDLMG-------------------------------- 96
CCRK            ---GFVLAFEFMLSDLAE-------------------------------- 87
CDK11           --RKVWLLFDYAEHDLWH-------------------------------- 87
CDK8            --RKVWLLFDYAEHDLWH-------------------------------- 87
IKKA            IHDVPLLAMEYCSGGDLRKLLNKPE-N----------------------- 98
IKKB            PNDLPLLAMEYCQGGDLRKYLNQFE-N----------------------- 99
1PHK            TNTFFFLVFDLMKKGELFDYLTEKV------------------------- 101
PHKG1           TNTFFFLVFDLMKRGELFDYLTEKV------------------------- 101
PHKG2           SSSFMFLVFDLMRKGELFDYLTEKV------------------------- 100
CAMK2A          EEGHHYLIFDLVTGGELFEDIVARE------------------------- 93
CAMK2B          EEGFHYLVFDLVTGGELFEDIVARE------------------------- 93
CAMK2G          EEGFHYLVFDLVTGGELFEDIVARE------------------------- 93
CAMK2D          EEGFHYLVFDLVTGGELFEDIVARE------------------------- 93
CASK            SDGMLYMVFEFMDGADLCFEIVKRADA----------------------- 98
1IA8A           EGNIQYLFLEYCSGGELFDRIEPDI------------------------- 89
CHK1            EGNIQYLFLEYCSGGELFDRIEPDI------------------------- 92
CLK1            HHGHICIVFELLGLST-YDFIKENG------------------------- 96
CLK4            HHGHVCIVFELLGLST-YDFIKENS------------------------- 95
CLK2            YHGHMCISFELLGLST-FDFLKDNN------------------------- 96
CLK3            FHGHMCIAFELLGKNT-FEFLKENN------------------------- 96
MAP2K5          VENRISICTEFMDGGSLD-VYRK--------------------------- 89
MAP2K3          REGDVWICMELMDT-SLDKFYRKV-------------------------- 91
MAP2K6          REGDVWICMELMDT-SLDKFYKQV-------------------------- 91
MAP2K4          REGDCWICMELMST-SFDKFYKYV-------------------------- 91
MAP2K7          TNTDVFIAMELMGT-CAEKLKKRM-------------------------- 91
MAP2K1          SDGEISICMEHMDGGSLDQ----V-------------------------- 87
MAP2K2          SDGEISICMEHMDGGSLDQ----V-------------------------- 87
CDKL5           RRGKLYLVFEYVEKNMLE-------------------------------- 86
CDKL1           RKRRLHLVFEYCDHTVLH-------------------------------- 86
CDKL4           RKRKMHLVFEYCDHTLLN-------------------------------- 86
CDKL2           KKKRWYLVFEFVDHTILD-------------------------------- 86
CDKL3           QKKKIHLVFEFIDHTVLD-------------------------------- 85
1I09B           DEVYLNLVLDYVPETVYR-------------------------------- 86
GSK3B           DEVYLNLVLDYVPETVYR-------------------------------- 86
1J1BA           DEVYLNLVLDYVPETVYR-------------------------------- 86
GSK3A           DELYLNLVLEYVPETVYR-------------------------------- 86
LATS1           DKDNLYFVMDYIPGGDMMSLLIRM-------------------------- 93
LATS2           DKDSLYFVMDYIPGGDMMSLLIRME------------------------- 94
NDR1            DKLNLYLIMEFLPGGDMMTLLMKK-------------------------- 93
NDR2            DKRNLYLIMEFLPGGDMMTLLMKK-------------------------- 93
MAST1           TRRHLCMVMEYVEGGDCATLLKNI-------------------------- 93
MAST4           TRRHLCMVMEYVEGGDCATLMKNM-------------------------- 93
MAST2           TKRHLCMVMEYVEGGDCATLLKNI-------------------------- 93
MAST3           TRRHLCMVMEYVEGGDCATLLKNM-------------------------- 93
MRCKA           DDNNLYLVMDYYVGGDLLTLLSKFE------------------------- 94
MRCKB           DENHLYLVMDYYVGGDLLTLLSKFE------------------------- 94
DMPK2           DEEYLYLVMDYYAGGDLLTLLSRFE------------------------- 94
DMPK1           DENYLYLVMEYYVGGDLLTLLSKFG------------------------- 94
ROCK1           DDRYLYMVMEYMPGGDLVNLMSNYD------------------------- 94
ROCK2           DDRYLYMVMEYMPGGDLVNLMSNYD------------------------- 94
CRIK            DKNHLYLVMEYQPGGDLLSLLNRYE------------------------- 94
MASTL           SANNVYLVMEYLIGGDVKSLLHIY-------------------------- 91
1O6LA           THDRLCFVMEYANGGELFFHLSRE-------------------------- 93
AKT2            THDRLCFVMEYANGGELFFHLSRE-------------------------- 93
AKT1            THDRLCFVMEYANGGELFFHLSRE-------------------------- 93
AKT3            TKDRLCFVMEYVNGGELFFHLSRE-------------------------- 93
MSK1            TETKLHLILDYINGGELFTHLSQR-------------------------- 98
MSK2            TDAKLHLILDYVSGGEMFTHLYQR-------------------------- 98
P70S6K          TGGKLYLILEYLSGGELFMQLERE-------------------------- 97
P70S6KB         TGGKLYLILECLSGGELFTHLERE-------------------------- 97
RSK1            TEGKLYLILDFLRGGDLFTRLSKE-------------------------- 95
RSK3            TEGKLYLILDFLRGGDLFTRLSKE-------------------------- 95
RSK2            TEGKLYLILDFLRGGDLFTRLSKE-------------------------- 95
RSK4            TEGKLYLILDFLRGGDVFTRLSKE-------------------------- 95
1FOTA           DAQQIFMIMDYIEGGELFSLLRKS-------------------------- 93
1CDKA           DNSNLYMVMEYVPGGEMFSHLRRI-------------------------- 93
PKACA           DNSNLYMVMEYVPGGEMFSHLRRI-------------------------- 93
PKACB           DNSNLYMVMEYVPGGEMFSHLRRI-------------------------- 93
PKACG           DNSYLYLVMEYVPGGEMFSRLQRV-------------------------- 93
PRKX            DERFLYMLMEYVPGGELFSYLRNR-------------------------- 93
PRKY            EERFLYMLMEYVPGGELFSYLRNR-------------------------- 93
PKCA            TVDRLYFVMEYVNGGDLMYHIQQV-------------------------- 94
PKCB            TMDRLYFVMEYVNGGDLMYHIQQV-------------------------- 94
PKCG            TPDRLYFVMEYVTGGDLMYHIQQL-------------------------- 99
PKCE            TKDRLFFVMEYVNGGDLMFQIQRS-------------------------- 94
PKCH            TPDRLFFVMEFVNGGDLMFHIQKS-------------------------- 94
PKCD            TKDHLFFVMEFLNGGDLMYHIQDK-------------------------- 94
PKCT            TKENLFFVMEYLNGGDLMYHIQSC-------------------------- 94
PKCI            TESRLFFVIEYVNGGDLMFHMQRQ-------------------------- 94
PKCZ            TTSRLFLVIEYVNGGDLMFHMQRQ-------------------------- 94
PKN1            TPEHVCFVMEYSAGGDLMLHIHS--------------------------- 95
PKN2            TKEHVCFVMEYAAGGDLMMHIHT--------------------------- 95
PKN3            TSSHARFVTEFVPGGDLMMQIHE--------------------------- 95
SGK             TADKLYFVLDYINGGELFYHLQRE-------------------------- 94
SGK2            TPEKLYFVLDYVNGGELFFHLQRE-------------------------- 94
SGK3            TTEKLYFVLDFVNGGELFFHLQRE-------------------------- 94
PKG1            DSKYLYMLMEACLGGELWTILRDR-------------------------- 94
PKG2            DNKYVYMLLEACLGGELWSILRDR-------------------------- 93
AURB            DRRRIYLILEYAPRGELYKEL----QK----------------------- 92
AURC            DARRVYLILEYAPRGELYKEL----QK----------------------- 92
AURA            DATRVYLILEYAPLGTVYREL----QK----------------------- 92
AURORA2_AVE     DATRVYLILEYAPLGTVYREL----QK----------------------- 92
PLK1            DNDFVFVVLELCRRRSLLELH----KR----------------------- 92
PLK2            DKENIYILLEYCSRRSMAHIL----KA----------------------- 92
PLK3            DADNIYIFLELCSRKSLAHIW----KA----------------------- 92
PLK4            DSNYVYLVLEMCHNGEMNRYL----KN----------------------- 92
NEK11           EQDNFCIITEYCEGRDLDDKIQEYKQA----------------------- 98
YANK1           DEEDMFMVVDLLLGGDLRYHLQQN-------------------------- 93
YANK2           DEEDMFMVVDLLLGGDLRYHLQQN-------------------------- 93
YANK3           DEEDMFMVVDLLLGGDLRYHLQQN-------------------------- 93
SGK494          GKRHLFIMCSYC-STDLYSLWSAV-------------------------- 92
DOMAIN2_MSK1    --LHTFLVMELLNGGELFERIKK--------------------------- 87
DOMAIN2_MSK2    --LHTYLVLELLRGGELLEHIRK--------------------------- 81
DOMAIN2_RSK1    --KFVYLVMELMRGGELLDRILR--------------------------- 86
DOMAIN2_RSK2    --KYVYVVTELMKGGELLDKILR--------------------------- 86
DOMAIN2_RSK3    --KHVYLVTELMRGGELLDKILR--------------------------- 86
DOMAIN2_RSK4    --RYVYLVTDLMKGGELLDRILK--------------------------- 86
DRAK1           --SEMILVLEYAAGGEIFDQCVA--------------------------- 92
DRAK2           --SEIILILEYAAGGEIFSLCLP--------------------------- 92
1JKSA           --TDVILILELVAGGELFDFLAE--------------------------- 95
DAPK1           --TDVILILELVAGGELFDFLAE--------------------------- 95
DAPK3           --TDVVLILELVSGGELFDFLAE--------------------------- 95
DAPK2           --TDVVLILELVSGGELFDFLAQ--------------------------- 95
SGK085          --NDIVLVMEYVDGGELFDRIID--------------------------- 89
CAMLCK          --HSCTLVMEYVDGGELFDRITD--------------------------- 89
SKMLCK          --HEIVLFMEYIEGGELFERIVD--------------------------- 89
SMMLCK          --ANIVMVLEIVSGGELFERIID--------------------------- 89
1KOBA           --YEMVLILEFLSGGELFDRIAA--------------------------- 89
1TKIA           --EELVMIFEFISGLDIFERINT--------------------------- 88
TTN             --EELVMIFEFISGLDIFERINT--------------------------- 88
PKD1            --ERVFVVMEKLHG-DMLEMILS--------------------------- 90
PKD3            --ERVFVVMEKLHG-DMLEMILS--------------------------- 90
PKD2            --EKVFVVMEKLHG-DMLEMILS--------------------------- 90
PSKH1           --ERVYMVMELATGGELFDRIIA--------------------------- 89
PSKH2           --DQVYMVMELATGGELFDRLIA--------------------------- 89
CAMK1A          --GHLYLIMQLVSGGELFDRIVE--------------------------- 90
CAMK1D          --NHLYLVMQLVSGGELFDRIVE--------------------------- 90
CAMK1B          --SHLYLAMELVTGGELFDRIME--------------------------- 90
CAMK1G          --THYYLVMQLVSGGELFDRILE--------------------------- 89
CAMK4           --TEISLVLELVTGGELFDRIVE--------------------------- 87
DCAMKL1         --TELYLVMELVKGGDLFDAITS--------------------------- 90
DCAMKL2         --TELFLVMELVKGGDLFDAITS--------------------------- 90
DCAMKL3         --MEIYLILEYVQGGDLFDAIIE--------------------------- 90
CHK2            ---DYYIVLELMEGGELFDKVVG--------------------------- 96
MAPKAPK2        GRKCLLIVMECLDGGELFSRIQD--------------------------- 89
MAPKAPK3        GKRCLLIIMECMEGGELFSRIQE--------------------------- 89
MAPKAPK5        PRARLLIVMEMMEGGELFHRISQ--------------------------- 95
MNK1            --TRFYLVFEKLQGGSILAHIQK--------------------------- 91
MNK2            --DRFYLVFEKMRGGSILSHIHK--------------------------- 90
VACAMKL         --KEYFIFLELATGREVFDWILD--------------------------- 90
GCK             --DRLWICMEFCGGGSLQEIYHAT-------------------------- 90
KHS1            --EKLWICMEYCGGGSLQDIYHVT-------------------------- 90
KHS2            --DKLWICMEFCGGGSLQDIYHVT-------------------------- 90
HPK1            --QKLWICMEFCGAGSLQDIYQVT-------------------------- 90
MST1            --TDLWIVMEYCGAGSVSDIIRLR-------N------------------ 89
MST2            --TDLWIVMEYCGAGSVSDIIRLR-------N------------------ 89
MST3            --TKLWIIMEYLGGGSALDLLE---------P------------------ 90
YSK1            --TKLWIIMEYLGGGSALDLLK---------P------------------ 90
MST4            --SKLWIIMEYLGGGSALDLLR---------A------------------ 90
LOK             --GKLWIMIEFCPGGAVDAIMLEL-------D------------------ 91
SLK             --NNLWILIEFCAGGAVDAVMLEL-------E------------------ 91
MAP3K4          --EEMYIFMEYCDEGTLEEVSRL--------------------------- 91
MAP3K2          -EKTLSIFMEYMPGGSIKDQLKA--------Y------------------ 97
MAP3K3          -EKTLTIFMEYMPGGSVKDQLKA--------Y------------------ 97
MAP3K8          --NTVSIFMEFVPGGSISSIINR--------F------------------ 95
MAP3K5          --GFIKIFMEQVPGGSLSALLRSK-------W------------------ 96
MAP3K7          --GYIKIFMEQVPGGSLSALLRSK-------W------------------ 89
MAP3K6          --GYLKIFMEEVPGGSLSSLLRSV-------W------------------ 86
PAK1            --DELWVVMEYLAGGSLTDVVTE--------T------------------ 90
PAK3            --DELWVVMEYLAGGSLTDVVTE--------T------------------ 90
PAK2            --DELFVVMEYLAGGSLTDVVTE--------T------------------ 90
PAK4            --DELWVVMEFLEGGALTDIVTHT-------------------------- 90
PAK5            --DELWVVMEFLEGGALTDIVTHT-------------------------- 90
PAK6            --EELWVLMEFLQGGALTDIVSQV-------------------------- 90
OSR1            --DELWLVMKLLSGGSVLDIIKHIVAKGEHKS------------------ 99
STLK3           --DELWLVMKLLSGGSMLDIIKYIVNRGEHKN------------------ 99
TAO1            --HTAWLVMEYCLG-SASDLLEVH-------K------------------ 93
TAO3            --HTAWLVMEYCLG-SASDLLEVH-------K------------------ 93
TAO2            --HTAWLVMEYCLG-SASDLLEVH-------K------------------ 93
MYO3A           NGDKLWLVLELCSGGSVTDLVKGFLK----RG------------------ 99
MYO3B           VGGQLWLVLELCNGGSVTELVKGLLR----CG------------------ 99
ZC1/HGK         HDDQLWLVMEFCGAGSITDLVKNT------KG------------------ 98
ZC3/MINK        NDDQLWLVMEFCGAGSVTDLVKNT------KG------------------ 98
ZC2/TNIK        MDDQLWLVMEFCGAGSVTDLIKNT------KG------------------ 98
ZC4/NRK         QRHQLWMVMELCAAGSVTDVVRMT------SN------------------ 122
MAP3K1          --SNYNLFIEWMAGGSVAHLLSK--------Y------------------ 96
GAK             GQAEFLLLTELC-KGQLVEFLKKMESR----------------------- 101
SGK495          ---------------NLQHYVI---KE----------------------- 9
TRB1            ET-KAYVFFEK-DFGDMHSYVR---SR----------------------- 76
TRB2            ET-KAYVFFER-SYGDMHSFVR---TC----------------------- 81
TRB3            TQ-LLYAFFTR-THGDMHSLVR---SR----------------------- 79
SSTK            CNGKLYIVME-AAATDLLQAVQ---RN----------------------- 93
TSSK3           ADGKICLVMELAEGGDVFDCVL---NG----------------------- 94
TSSK1           SHGKVYIVMELAVQGDLLELIK---TR----------------------- 94
TSSK2           SDGRIYIIMELGVQGDLLEFIK---CQ----------------------- 94
TSSK4           TS-RVYIILELAQGGDVLEWIQ---RY----------------------- 93
HUNK            EN-SYYLVMELCPGGNLMHKIY---EK----------------------- 95
SNRK            QT-KLYLILELGDGGDMFDYIM---KH----------------------- 92
NIM1            LS-KLHLVMEYAGGGELFGKIS---TE----------------------- 92
MELK            AN-KIFMVLEYCPGGELFDYII---SQ----------------------- 91
BRSK1           KK-YLYLVLEHVSGGELFDYLV---KK----------------------- 92
BRSK2           KK-YLYLVLEHVSGGELFDYLV---KK----------------------- 92
MARK1           EK-TLYLVMEYASGGEVFDYLV---AH----------------------- 92
MARK2           EK-TLYLVMEYASGGEVFDYLV---AH----------------------- 92
MARK3           QK-TLYLIMEYASGGKVFDYLV---AH----------------------- 92
MARK4           EK-TLYLVMEYASAGEVFDYLV---SH----------------------- 92
QIK             KS-MLYLVTEYAKNGEIFDYLA---NH----------------------- 92
SIK             KD-MLYIVTEFAKNGEMFDYLT---SN----------------------- 92
QSK             ER-MIYLVTEYASGGEIFDHLV---AH----------------------- 92
AMPKA1          PS-DIFMVMEYVSGGELFDYIC---KN----------------------- 93
AMPKA2          PT-DFFMVMEYVSGGELFDYIC---KH----------------------- 93
NUAK1           KD-KIVIIMEYASKGELYDYIS---ER----------------------- 93
NUAK2           SS-KIVIVMEYASRGDLYDYIS---ER----------------------- 92
BIKE            VW-EVLILMEYCRAGQVVNQMN---KK----------------------- 95
AAK1            DVWEVLILMDFCRGGQVVNLMN---QR----------------------- 96
LIMK1           -DKRLNFITEYIKGGTLRGIIKSMDSQ----------------------- 93
LIMK2           -DKKLNLLTEYIEGGTLKDFLRSMD------------------------- 91
TESK1           -QGQLHALTEYMNGGTLEQLLSSPE------------------------- 89
TESK2           -----------INSGNLEQLLDSNL------------------------- 69
WNK1            GKKCIVLVTELMTSGTLKTYLKRFK------------------------- 97
WNK3            GKKCIVLVTELMTSGTLKTYLKRFK------------------------- 97
WNK2            GKRCIVLVTELMTSGTLKTYLKRFK------------------------- 97
WNK4            GQVCIVLVTELMTSGTLKTYLRRFR------------------------- 97
NEK10           -NDRLYIVMELIEGAPLGEHFSSLKEK----------------------- 104
NEK6            -DNELNIVLELADAGDLSQMIKYFKKQ----------------------- 96
NEK7            -DNELNIVLELADAGDLSRMIKHFKKQ----------------------- 96
NEK2            TNTTLYIVMEYCEGGDLASVITKGTKE----------------------- 97
NEK1            -NGSLYIVMDYCEGGDLFKRINA--QK----------------------- 93
NEK5            -NGRLFIVMEYCDGGDLMKRINR--QR----------------------- 93
NEK3            -EGHLYIVMEYCDGGDLMQKIKQ--QK----------------------- 92
NEK4            GDGLLYIVMGFCEGGDLYRKLKE--QK----------------------- 94
NEK8            -DKALMIAMEYAPGGTLAEFIQK--RC----------------------- 93
NEK9            -NTTLLIELEYCNGGNLYDKILR--QK----------------------- 93
NRBP1           NKARVIFITEYMSSGSLKQFLKKTKKN----------------------- 104
NRBP2           ACARVIFITEYVSSGSLKQFLKKTKKN----------------------- 104
CLIK1           EPCYLWFVMEFCEGGDLNQYVLSRRP------------------------ 131
CLIK1L          SAYYLWFVMDFCDGGDMNEYLLSRKP------------------------ 129
STK33           TPKKMYLVMELCEDGELKEILDRKGH------------------------ 94
DOMAIN2_GCN2    DSIVVDILVEHISGVSLAA------------------------------- 110
SCYL1           ----LHVVTEAVT--PLGIYLKAR-------------------------- 78
SCYL3           ----IHLVTERVQ--PLEVAL----------------------------- 68
DOMAIN2_JAK1    ENIMV---EEFVEGGPLDLFMHR-KSD----------------------- 102
DOMAIN2_TYK2    ENSMV---TEYVEHGPLDVWLRR-ERG----------------------- 116
DOMAIN2_JAK2    ENILV---QEFVKFGSLDTYLKK-NKN----------------------- 99
DOMAIN2_JAK3    -STMV---QEFVHLGAIDMYLRK-RGH----------------------- 97
ILK             HPTLIT---HWMPYGSLYNVLHEG-------------------------- 92
LRRK1           PLCFA---LELAPLSSLNTVLSEN-------------------------- 108
PBK             SLCLA---MEYGGEKSLNDLIEER-------------------------- 99
WEE1            HMLIQ---NEYCNGGSLADAISEN-------------------------- 93
WEE1B           HMIIQ---NEYCNGGSLQAAISEN-------------------------- 93
SGK071          YLCLV---MEFNEL-SFQEVIEDK-------------------------- 95
PIK3R4          AAMLF---RQYVRDNLYD-------------------------------- 87
MSSK1           HVCMV---LEVLGHQLLKWIIKS-NYQG---------------------- 104
SRPK1           HICMV---FEVLGHHLLKWIIKS-NYQG---------------------- 104
SRPK2           HVCMV---FEVLGHHLLKWIIKS-NYQG---------------------- 104
RSKL1           -------------------------------------------------- 74
RSKL2           ----------------QSCLSADGAGRG---------------------- 224
SGK396          MAYLM---VPYYPRANLNA------------------------------- 87
VRK1            YRFMI---MDRFGSD-LQKIYEAN-------------------------- 109
VRK2            YRFMV---MERLGIDLQK-------------------------------- 102
VRK3            YRFLV---LPSLGR-SLQSALDV--------------------------- 52
BUB1            GSVLV---GELYSYGTLLNAINLY-------------------------- 95
BUBR1           GCIVW---HQYINCFTLQD------------------------------- 94
SGK196          -NTMLT---EYHPLGSLSN-LEE--------------------------- 82
SGK493          IPDTLTTITELGA--PVEMI------------------------------ 102
                                                                  

DYRK1A          -------------------------------------------------- 95
DYRK1B          -------------------------------------------------- 95
DYRK2           -------------------------------------------------- 95
DYRK3           -------------------------------------------------- 95
DYRK4           -------------------------------------------------- 95
HIPK1           -------------------------------------------------- 94
HIPK2           -------------------------------------------------- 94
HIPK3           -------------------------------------------------- 94
HIPK4           -------------------------------------------------- 94
PRP4            -------------------------------------------------- 96
MOK             -------------------------------------------------- 94
1A6O            -------------------------------------------------- 86
1LPUA           -------------------------------------------------- 86
CK2A1           -------------------------------------------------- 86
CK2A1-RS        -------------------------------------------------- 86
CK2A2           -------------------------------------------------- 86
HSER            -------------------------------------------------- 92
SLOB            -------------------------------------------------- 97
CDC7            -------------------------------------------------- 88
1CSN            -------------------------------------------------- 89
CK1G1           -------------------------------------------------- 90
CK1G3           -------------------------------------------------- 89
CK1G2           -------------------------------------------------- 89
CK1A            -------------------------------------------------- 89
CK1A2           -------------------------------------------------- 89
1CKJA           -------------------------------------------------- 89
CK1D            -------------------------------------------------- 89
CK1E            -------------------------------------------------- 89
TTBK1           -------------------------------------------------- 89
TTBK2           -------------------------------------------------- 89
TLK1            -------------------------------------------------- 98
TLK2            -------------------------------------------------- 98
GPRK4           -------------------------------------------------- 94
GPRK6           -------------------------------------------------- 94
GPRK5           -------------------------------------------------- 94
RHOK            -------------------------------------------------- 94
GPRK7           -------------------------------------------------- 94
BARK1           -------------------------------------------------- 96
BARK2           -------------------------------------------------- 96
TTK             -------------------------------------------------- 92
RIPK1           -------------------------------------------------- 93
HASPIN          -------------------------------------------------- 137
GCN2            -------------------------------------------------- 230
HRI             -------------------------------------------------- 242
KIS             -------------------------------------------------- 108
PDK1            -------------------------------------------------- 95
PKR             -------------------------------------------------- 119
PEK             -------------------------------------------------- 316
PRPK            -------------------------------------------------- 100
DOMAIN2_OBSCN   -------------------------------------------------- 90
DOMAIN2_SPEG    -------------------------------------------------- 90
LMR1            -------------------------------------------------- 99
LMR2            -------------------------------------------------- 94
LMR3            -------------------------------------------------- 99
SGK307          -------------------------------------------------- 6
STLK5           -------------------------------------------------- 96
STLK6           -------------------------------------------------- 96
STLK6-RS        -------------------------------------------------- 96
OBSCN           -------------------------------------------------- 90
SPEG            -------------------------------------------------- 89
TRAD            -------------------------------------------------- 90
TRIO            -------------------------------------------------- 90
SGK223          -------------------------------------------------- 96
SGK269          -------------------------------------------------- 99
ALK1            -------------------------------------------------- 90
ALK2            -------------------------------------------------- 90
IRAK4           -------------------------------------------------- 95
BMPR2           -------------------------------------------------- 91
TGFBR2          -------------------------------------------------- 96
ACTR2           -------------------------------------------------- 90
ACTR2B          -------------------------------------------------- 90
1B6CB           -------------------------------------------------- 90
TGFBR1          -------------------------------------------------- 90
ALK4            -------------------------------------------------- 90
ALK7            -------------------------------------------------- 90
BMPR1A          -------------------------------------------------- 90
BMPR1B          -------------------------------------------------- 90
IRAK1           -------------------------------------------------- 96
IRAK2           -------------------------------------------------- 90
IRAK3           -------------------------------------------------- 90
MISR2           -------------------------------------------------- 90
MYT1            -------------------------------------------------- 90
SBK             -------------------------------------------------- 89
SGK110          -------------------------------------------------- 89
SGK069          -------------------------------------------------- 89
SGK496          -------------------------------------------------- 91
NIK             -------------------------------------------------- 83
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 102
IKKE            -------------------------------------------------- 92
TBK1            -------------------------------------------------- 92
MOS             -------------------------------------------------- 92
LKB1            -------------------------------------------------- 94
CAMKK1          -------------------------------------------------- 122
CAMKK2          -------------------------------------------------- 114
PASK            -------------------------------------------------- 95
PIM1            -------------------------------------------------- 95
PIM3            -------------------------------------------------- 96
PIM2            -------------------------------------------------- 97
COT             -------------------------------------------------- 83
SCYL2           -------------------------------------------------- 99
FUSED           -------------------------------------------------- 92
ULK1            -------------------------------------------------- 93
ULK2            -------------------------------------------------- 93
ULK3            -------------------------------------------------- 94
ULK4            -------------------------------------------------- 73
IRE1            -------------------------------------------------- 87
IRE2            -------------------------------------------------- 87
RNASEL          -------------------------------------------------- 82
MPSK1           -------------------------------------------------- 94
PINK1           -------------------------------------------------- 175
ALK             -------------------------------------------------- 102
LTK             -------------------------------------------------- 102
ROS             -------------------------------------------------- 103
IGF1R           -------------------------------------------------- 102
1IR3A           -------------------------------------------------- 102
INSR            -------------------------------------------------- 102
IRR             -------------------------------------------------- 102
1M14A           -------------------------------------------------- 97
EGFR            -------------------------------------------------- 97
HER2/ERBB2      -------------------------------------------------- 97
HER4/ERBB4      -------------------------------------------------- 97
HER3/ERBB3      -------------------------------------------------- 97
ITK             -------------------------------------------------- 91
TEC             -------------------------------------------------- 91
TXK             -------------------------------------------------- 91
BMX             -------------------------------------------------- 91
1K2PA           -------------------------------------------------- 91
BTK             -------------------------------------------------- 91
CCK4            -------------------------------------------------- 101
ROR1            -------------------------------------------------- 102
ROR2            -------------------------------------------------- 102
MUSK            -------------------------------------------------- 102
TRKA            -------------------------------------------------- 101
TRKB            -------------------------------------------------- 101
TRKC            -------------------------------------------------- 101
DDR1            -------------------------------------------------- 114
DDR2            -------------------------------------------------- 113
RYK             -------------------------------------------------- 103
JAK1            -------------------------------------------------- 98
JAK2            -------------------------------------------------- 98
JAK3            -------------------------------------------------- 98
ACK             -------------------------------------------------- 97
TYK2            -------------------------------------------------- 98
TNK1            -------------------------------------------------- 98
EPHA1           -------------------------------------------------- 95
EPHA10          -------------------------------------------------- 95
FAK             -------------------------------------------------- 94
EPHB6           -------------------------------------------------- 95
EPHA2           -------------------------------------------------- 96
EPHA8           -------------------------------------------------- 95
EPHA6           -------------------------------------------------- 137
EPHB1           -------------------------------------------------- 95
EPHB2           -------------------------------------------------- 95
EPHB3           -------------------------------------------------- 95
EPHB4           -------------------------------------------------- 95
EPHA7           -------------------------------------------------- 95
EPHA4           -------------------------------------------------- 95
EPHA3           -------------------------------------------------- 95
EPHA5           -------------------------------------------------- 95
PYK2            -------------------------------------------------- 94
CSK             -------------------------------------------------- 89
CTK             -------------------------------------------------- 87
1IEPA           -------------------------------------------------- 91
ABL             -------------------------------------------------- 91
ARG             -------------------------------------------------- 91
BRK             -------------------------------------------------- 91
SRM             -------------------------------------------------- 90
FRK             -------------------------------------------------- 90
FGR             -------------------------------------------------- 89
FYN             -------------------------------------------------- 89
SRC             -------------------------------------------------- 89
YES             -------------------------------------------------- 89
HCK             -------------------------------------------------- 89
LYN             -------------------------------------------------- 90
3LCK            -------------------------------------------------- 89
LCK             -------------------------------------------------- 89
BLK             -------------------------------------------------- 89
FER             -------------------------------------------------- 91
FES             -------------------------------------------------- 92
SYK             -------------------------------------------------- 94
ZAP70           -------------------------------------------------- 93
FGFR1           -------------------------------------------------- 106
FGFR2           -------------------------------------------------- 106
FGFR3           -------------------------------------------------- 106
FGFR4           -------------------------------------------------- 106
RET             -------------------------------------------------- 108
TIE1            -------------------------------------------------- 101
1FVRA           -------------------------------------------------- 101
TIE2            -------------------------------------------------- 101
FLT1            EQGKKPRLDSVTSSE------------------------------SFASS 143
KDR             PVDLKRRLDSITSSQ------------------------------SSASS 142
KDR_AVE         -------------------------------------------------- 106
FLT4            ELARLDRRRPGSSDR------------------------------VLFAR 140
FMS             LEKKYVRRDSGFSSQGVDTYVEMRPVST---------------------- 150
FLT3            QSHPN---------SSMPGSREVQIHPDSDQISGL------------HGN 149
KIT             HSKESSCS------DSTNEYMDMKPG--VSYVVPT--------------K 147
PDGFRA          PADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSL 169
PDGFRB          PVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSN 171
MER             -------------------------------------------------- 106
AXL             -------------------------------------------------- 106
TYRO3           -------------------------------------------------- 107
MET             -------------------------------------------------- 96
RON             -------------------------------------------------- 96
HH498           -------------------------------------------------- 97
LZK             -------------------------------------------------- 82
DLK             -------------------------------------------------- 82
MLK1            -------------------------------------------------- 92
MLK3            -------------------------------------------------- 92
MLK2            -------------------------------------------------- 92
MLK4            -------------------------------------------------- 99
ZAK             -------------------------------------------------- 88
TAK1            -------------------------------------------------- 89
KSR1            -------------------------------------------------- 94
KSR2            -------------------------------------------------- 94
ARAF            -------------------------------------------------- 93
RAF1            -------------------------------------------------- 93
BRAF            -------------------------------------------------- 93
LRRK2           -------------------------------------------------- 89
ANKRD3          -------------------------------------------------- 91
SGK288          -------------------------------------------------- 90
RIPK2           -------------------------------------------------- 98
RIPK3           -------------------------------------------------- 93
MLKL            -------------------------------------------------- 95
ANPA            -------------------------------------------------- 98
ANPB            -------------------------------------------------- 98
CYGD            -------------------------------------------------- 107
CYGF            -------------------------------------------------- 112
TBCK            -------------------------------------------------- 68
ERK1            -------------------------------------------------- 90
3ERK            -------------------------------------------------- 90
ERK2            -------------------------------------------------- 90
ERK5            -------------------------------------------------- 92
1JNK            -------------------------------------------------- 92
1PMNA           -------------------------------------------------- 92
JNK3            -------------------------------------------------- 92
JNK1            -------------------------------------------------- 92
JNK2            -------------------------------------------------- 92
1P38            -------------------------------------------------- 92
P38A            -------------------------------------------------- 92
P38B            -------------------------------------------------- 92
P38D            -------------------------------------------------- 92
P38G            -------------------------------------------------- 92
NLK             -------------------------------------------------- 91
ERK7            -------------------------------------------------- 108
ERK3            -------------------------------------------------- 98
ERK4            -------------------------------------------------- 95
ICK             -------------------------------------------------- 85
MAK             -------------------------------------------------- 85
PCTAIRE1        -------------------------------------------------- 85
PCTAIRE2        -------------------------------------------------- 85
PCTAIRE3        -------------------------------------------------- 85
PFTAIRE1        -------------------------------------------------- 85
PFTAIRE2        -------------------------------------------------- 85
CDC2            -------------------------------------------------- 86
1HCL            -------------------------------------------------- 82
CDK2            -------------------------------------------------- 86
CDK3            -------------------------------------------------- 86
CDK5            -------------------------------------------------- 86
CDK7            -------------------------------------------------- 89
CDK4            -------------------------------------------------- 97
1BLXA           -------------------------------------------------- 95
CDK6            -------------------------------------------------- 95
PITSLRE         -------------------------------------------------- 88
CDK10           -------------------------------------------------- 88
CDK9            -------------------------------------------------- 94
CHED            -------------------------------------------------- 96
CRK7            -------------------------------------------------- 96
CCRK            -------------------------------------------------- 87
CDK11           -------------------------------------------------- 87
CDK8            -------------------------------------------------- 87
IKKA            -------------------------------------------------- 98
IKKB            -------------------------------------------------- 99
1PHK            -------------------------------------------------- 101
PHKG1           -------------------------------------------------- 101
PHKG2           -------------------------------------------------- 100
CAMK2A          -------------------------------------------------- 93
CAMK2B          -------------------------------------------------- 93
CAMK2G          -------------------------------------------------- 93
CAMK2D          -------------------------------------------------- 93
CASK            -------------------------------------------------- 98
1IA8A           -------------------------------------------------- 89
CHK1            -------------------------------------------------- 92
CLK1            -------------------------------------------------- 96
CLK4            -------------------------------------------------- 95
CLK2            -------------------------------------------------- 96
CLK3            -------------------------------------------------- 96
MAP2K5          -------------------------------------------------- 89
MAP2K3          -------------------------------------------------- 91
MAP2K6          -------------------------------------------------- 91
MAP2K4          -------------------------------------------------- 91
MAP2K7          -------------------------------------------------- 91
MAP2K1          -------------------------------------------------- 87
MAP2K2          -------------------------------------------------- 87
CDKL5           -------------------------------------------------- 86
CDKL1           -------------------------------------------------- 86
CDKL4           -------------------------------------------------- 86
CDKL2           -------------------------------------------------- 86
CDKL3           -------------------------------------------------- 85
1I09B           -------------------------------------------------- 86
GSK3B           -------------------------------------------------- 86
1J1BA           -------------------------------------------------- 86
GSK3A           -------------------------------------------------- 86
LATS1           -------------------------------------------------- 93
LATS2           -------------------------------------------------- 94
NDR1            -------------------------------------------------- 93
NDR2            -------------------------------------------------- 93
MAST1           -------------------------------------------------- 93
MAST4           -------------------------------------------------- 93
MAST2           -------------------------------------------------- 93
MAST3           -------------------------------------------------- 93
MRCKA           -------------------------------------------------- 94
MRCKB           -------------------------------------------------- 94
DMPK2           -------------------------------------------------- 94
DMPK1           -------------------------------------------------- 94
ROCK1           -------------------------------------------------- 94
ROCK2           -------------------------------------------------- 94
CRIK            -------------------------------------------------- 94
MASTL           -------------------------------------------------- 91
1O6LA           -------------------------------------------------- 93
AKT2            -------------------------------------------------- 93
AKT1            -------------------------------------------------- 93
AKT3            -------------------------------------------------- 93
MSK1            -------------------------------------------------- 98
MSK2            -------------------------------------------------- 98
P70S6K          -------------------------------------------------- 97
P70S6KB         -------------------------------------------------- 97
RSK1            -------------------------------------------------- 95
RSK3            -------------------------------------------------- 95
RSK2            -------------------------------------------------- 95
RSK4            -------------------------------------------------- 95
1FOTA           -------------------------------------------------- 93
1CDKA           -------------------------------------------------- 93
PKACA           -------------------------------------------------- 93
PKACB           -------------------------------------------------- 93
PKACG           -------------------------------------------------- 93
PRKX            -------------------------------------------------- 93
PRKY            -------------------------------------------------- 93
PKCA            -------------------------------------------------- 94
PKCB            -------------------------------------------------- 94
PKCG            -------------------------------------------------- 99
PKCE            -------------------------------------------------- 94
PKCH            -------------------------------------------------- 94
PKCD            -------------------------------------------------- 94
PKCT            -------------------------------------------------- 94
PKCI            -------------------------------------------------- 94
PKCZ            -------------------------------------------------- 94
PKN1            -------------------------------------------------- 95
PKN2            -------------------------------------------------- 95
PKN3            -------------------------------------------------- 95
SGK             -------------------------------------------------- 94
SGK2            -------------------------------------------------- 94
SGK3            -------------------------------------------------- 94
PKG1            -------------------------------------------------- 94
PKG2            -------------------------------------------------- 93
AURB            -------------------------------------------------- 92
AURC            -------------------------------------------------- 92
AURA            -------------------------------------------------- 92
AURORA2_AVE     -------------------------------------------------- 92
PLK1            -------------------------------------------------- 92
PLK2            -------------------------------------------------- 92
PLK3            -------------------------------------------------- 92
PLK4            -------------------------------------------------- 92
NEK11           -------------------------------------------------- 98
YANK1           -------------------------------------------------- 93
YANK2           -------------------------------------------------- 93
YANK3           -------------------------------------------------- 93
SGK494          -------------------------------------------------- 92
DOMAIN2_MSK1    -------------------------------------------------- 87
DOMAIN2_MSK2    -------------------------------------------------- 81
DOMAIN2_RSK1    -------------------------------------------------- 86
DOMAIN2_RSK2    -------------------------------------------------- 86
DOMAIN2_RSK3    -------------------------------------------------- 86
DOMAIN2_RSK4    -------------------------------------------------- 86
DRAK1           -------------------------------------------------- 92
DRAK2           -------------------------------------------------- 92
1JKSA           -------------------------------------------------- 95
DAPK1           -------------------------------------------------- 95
DAPK3           -------------------------------------------------- 95
DAPK2           -------------------------------------------------- 95
SGK085          -------------------------------------------------- 89
CAMLCK          -------------------------------------------------- 89
SKMLCK          -------------------------------------------------- 89
SMMLCK          -------------------------------------------------- 89
1KOBA           -------------------------------------------------- 89
1TKIA           -------------------------------------------------- 88
TTN             -------------------------------------------------- 88
PKD1            -------------------------------------------------- 90
PKD3            -------------------------------------------------- 90
PKD2            -------------------------------------------------- 90
PSKH1           -------------------------------------------------- 89
PSKH2           -------------------------------------------------- 89
CAMK1A          -------------------------------------------------- 90
CAMK1D          -------------------------------------------------- 90
CAMK1B          -------------------------------------------------- 90
CAMK1G          -------------------------------------------------- 89
CAMK4           -------------------------------------------------- 87
DCAMKL1         -------------------------------------------------- 90
DCAMKL2         -------------------------------------------------- 90
DCAMKL3         -------------------------------------------------- 90
CHK2            -------------------------------------------------- 96
MAPKAPK2        -------------------------------------------------- 89
MAPKAPK3        -------------------------------------------------- 89
MAPKAPK5        -------------------------------------------------- 95
MNK1            -------------------------------------------------- 91
MNK2            -------------------------------------------------- 90
VACAMKL         -------------------------------------------------- 90
GCK             -------------------------------------------------- 90
KHS1            -------------------------------------------------- 90
KHS2            -------------------------------------------------- 90
HPK1            -------------------------------------------------- 90
MST1            -------------------------------------------------- 89
MST2            -------------------------------------------------- 89
MST3            -------------------------------------------------- 90
YSK1            -------------------------------------------------- 90
MST4            -------------------------------------------------- 90
LOK             -------------------------------------------------- 91
SLK             -------------------------------------------------- 91
MAP3K4          -------------------------------------------------- 91
MAP3K2          -------------------------------------------------- 97
MAP3K3          -------------------------------------------------- 97
MAP3K8          -------------------------------------------------- 95
MAP3K5          -------------------------------------------------- 96
MAP3K7          -------------------------------------------------- 89
MAP3K6          -------------------------------------------------- 86
PAK1            -------------------------------------------------- 90
PAK3            -------------------------------------------------- 90
PAK2            -------------------------------------------------- 90
PAK4            -------------------------------------------------- 90
PAK5            -------------------------------------------------- 90
PAK6            -------------------------------------------------- 90
OSR1            -------------------------------------------------- 99
STLK3           -------------------------------------------------- 99
TAO1            -------------------------------------------------- 93
TAO3            -------------------------------------------------- 93
TAO2            -------------------------------------------------- 93
MYO3A           -------------------------------------------------- 99
MYO3B           -------------------------------------------------- 99
ZC1/HGK         -------------------------------------------------- 98
ZC3/MINK        -------------------------------------------------- 98
ZC2/TNIK        -------------------------------------------------- 98
ZC4/NRK         -------------------------------------------------- 122
MAP3K1          -------------------------------------------------- 96
GAK             -------------------------------------------------- 101
SGK495          -------------------------------------------------- 9
TRB1            -------------------------------------------------- 76
TRB2            -------------------------------------------------- 81
TRB3            -------------------------------------------------- 79
SSTK            -------------------------------------------------- 93
TSSK3           -------------------------------------------------- 94
TSSK1           -------------------------------------------------- 94
TSSK2           -------------------------------------------------- 94
TSSK4           -------------------------------------------------- 93
HUNK            -------------------------------------------------- 95
SNRK            -------------------------------------------------- 92
NIM1            -------------------------------------------------- 92
MELK            -------------------------------------------------- 91
BRSK1           -------------------------------------------------- 92
BRSK2           -------------------------------------------------- 92
MARK1           -------------------------------------------------- 92
MARK2           -------------------------------------------------- 92
MARK3           -------------------------------------------------- 92
MARK4           -------------------------------------------------- 92
QIK             -------------------------------------------------- 92
SIK             -------------------------------------------------- 92
QSK             -------------------------------------------------- 92
AMPKA1          -------------------------------------------------- 93
AMPKA2          -------------------------------------------------- 93
NUAK1           -------------------------------------------------- 93
NUAK2           -------------------------------------------------- 92
BIKE            -------------------------------------------------- 95
AAK1            -------------------------------------------------- 96
LIMK1           -------------------------------------------------- 93
LIMK2           -------------------------------------------------- 91
TESK1           -------------------------------------------------- 89
TESK2           -------------------------------------------------- 69
WNK1            -------------------------------------------------- 97
WNK3            -------------------------------------------------- 97
WNK2            -------------------------------------------------- 97
WNK4            -------------------------------------------------- 97
NEK10           -------------------------------------------------- 104
NEK6            -------------------------------------------------- 96
NEK7            -------------------------------------------------- 96
NEK2            -------------------------------------------------- 97
NEK1            -------------------------------------------------- 93
NEK5            -------------------------------------------------- 93
NEK3            -------------------------------------------------- 92
NEK4            -------------------------------------------------- 94
NEK8            -------------------------------------------------- 93
NEK9            -------------------------------------------------- 93
NRBP1           -------------------------------------------------- 104
NRBP2           -------------------------------------------------- 104
CLIK1           -------------------------------------------------- 131
CLIK1L          -------------------------------------------------- 129
STK33           -------------------------------------------------- 94
DOMAIN2_GCN2    -------------------------------------------------- 110
SCYL1           -------------------------------------------------- 78
SCYL3           -------------------------------------------------- 68
DOMAIN2_JAK1    -------------------------------------------------- 102
DOMAIN2_TYK2    -------------------------------------------------- 116
DOMAIN2_JAK2    -------------------------------------------------- 99
DOMAIN2_JAK3    -------------------------------------------------- 97
ILK             -------------------------------------------------- 92
LRRK1           -------------------------------------------------- 108
PBK             -------------------------------------------------- 99
WEE1            -------------------------------------------------- 93
WEE1B           -------------------------------------------------- 93
SGK071          -------------------------------------------------- 95
PIK3R4          -------------------------------------------------- 87
MSSK1           -------------------------------------------------- 104
SRPK1           -------------------------------------------------- 104
SRPK2           -------------------------------------------------- 104
RSKL1           -------------------------------------------------- 74
RSKL2           -------------------------------------------------- 224
SGK396          -------------------------------------------------- 87
VRK1            -------------------------------------------------- 109
VRK2            -------------------------------------------------- 102
VRK3            -------------------------------------------------- 52
BUB1            -------------------------------------------------- 95
BUBR1           -------------------------------------------------- 94
SGK196          -------------------------------------------------- 82
SGK493          -------------------------------------------------- 102
                                                                  

DYRK1A          --------------------------FRGVSLNLTRKFAQQMCTALLFLA 119
DYRK1B          --------------------------FRGVSLNLTRKLAQQLCTALLFLA 119
DYRK2           --------------------------FQGFSLPLVRKFAHSILQCLDALH 119
DYRK3           --------------------------FQGFSVQLVRKFAQSILQSLDALH 119
DYRK4           --------------------------FQGFSLSIVRRFTLSVLKCLQMLS 119
HIPK1           --------------------------FSPLPLKYIRPILQQVATALMKLK 118
HIPK2           --------------------------FSPLPLKYIRPVLQQVATALMKLK 118
HIPK3           --------------------------FSPLPLKVIRPILQQVATALKKLK 118
HIPK4           --------------------------FAPLPARHIRTVTLQVLTALARLK 118
PRP4            -------------------------KDVGLHIKAVRSYSQQLFLALKLLK 121
MOK             ---------------------------YPLSEKKIMHYMYQLCKSLDHIH 117
1A6O            --------------------------YPTLTDYDIRYYIYELLKALDYCH 110
1LPUA           --------------------------YPTLTDYDIRYYIYELLKALDYCH 110
CK2A1           --------------------------YQTLTDYDIRFYMYEILKALDYCH 110
CK2A1-RS        --------------------------YQTFTDYDIRFYMYEILKALDYCH 110
CK2A2           --------------------------YQILTDFDIRFYMYELLKALDYCH 110
HSER            -------------------------DGTFMDWEFKISVLYDIAKGMSYLH 117
SLOB            ---------------PFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLH 132
CDC7            --------------------------LNSLSFQEVREYMLNLFKALKRIH 112
1CSN            ---------------------------RKFSVKTVAMAAKQMLARVQSIH 112
CK1G1           ---------------------------RTFTLKTVLMIAIQLLSRMEYVH 113
CK1G3           ---------------------------RTFSLKTVLMIAIQLISRMEYVH 112
CK1G2           ---------------------------RTFTLKTVLMIAIQLITRMEYVH 112
CK1A            ---------------------------RRFTMKTVLMLADQMISRIEYVH 112
CK1A2           ---------------------------RRFTMKTVLMLADQMISRIEYVH 112
1CKJA           ---------------------------RKFSLKTVLLLADQMISRIEYIH 112
CK1D            ---------------------------RKFSLKTVLLLADQMISRIEYIH 112
CK1E            ---------------------------RKFSLKTVLLLADQMISRIEYIH 112
TTBK1           --------------------------RGTFTLSTTLRLGKQILESIEAIH 113
TTBK2           --------------------------RGTFTISTTLRLGRQILESIESIH 113
TLK1            ---------------------------KLMSEKEARSIVMQIVNALRYLN 121
TLK2            ---------------------------KLMSEKEARSIIMQIVNALKYLN 121
GPRK4           --------------------------NPGFDEQRAVFYAAELCCGLEDLQ 118
GPRK6           --------------------------QAGFPEARAVFYAAEICCGLEDLH 118
GPRK5           --------------------------NPGFEEERALFYAAEILCGLEDLH 118
RHOK            ------------------------EENPGFPEPRALFYTAQIICGLEHLH 120
GPRK7           --------------------------TRGLDMSRVIFYSAQIACGMLHLH 118
BARK1           ---------------------------GVFSEADMRFYAAEIILGLEHMH 119
BARK2           ---------------------------GVFSEKEMRFYATEIILGLEHVH 119
TTK             ---------------------------KSIDPWERKSYWKNMLEAVHTIH 115
RIPK1           -----------------------------TPLSVKGRIILEIIEGMCYLH 114
HASPIN          ------------------------------SLATAKSILHQLTASLAVAE 157
GCN2            ------------------------RD-----TVRLWRLFREILDGLAYIH 251
HRI             ------------------------SACPYVMANVATKIFQELVEGVFYIH 268
KIS             --------------------------SMWMIQ----HCARDVLEALAFLH 128
PDK1            -----------------------------FDETCTRFYTAEIVSALEYLH 116
PKR             ------------------------LD-----KVLALELFEQITKGVDYIH 140
PEK             ------------------------RE-----RSVCLHIFLQIAEAVEFLH 337
PRPK            ------------------------EKTPQGLS----NLAKTIGQVLARMH 122
DOMAIN2_OBSCN   -----------------------SYSESEVK-----DYLWQMLSATQYLH 112
DOMAIN2_SPEG    -----------------------RYSEDDVA-----TYMVQLLQGLDYLH 112
LMR1            ---------------------A--PDPR-----TLQRMACEVACGVLHLH 121
LMR2            -----------------------EHMRGDSQTMLLQRMACEVAAGLAAMH 121
LMR3            ---------------------SPELPPRDLR--TLQRMGLEIARGLAHLH 126
SGK307          ----------------------PVLHMEVIV-----HLLLQISDALRYLH 29
STLK5           ----------------------DGMNELAIA-----YILQGVLKALDYIH 119
STLK6           ----------------------EGMSETLIR-----NILFGAVRGLNYLH 119
STLK6-RS        ----------------------EGMSETLIR-----NIIFGAVRGLNYLY 119
OBSCN           -----------------------VVTEAEVK-----VYIQQLVEGLHYLH 112
SPEG            -----------------------TVCESEIR-----AYMRQVLEGIHYLH 111
TRAD            -----------------------ELMEEKVA-----FYIRDIMEALQYLH 112
TRIO            -----------------------SLTEGKIR-----AHLGEVLEAVRYLH 112
SGK223          ---------------------EPEAYERRVC-----FLLLQLCNGLEHLK 120
SGK269          ---------------------SPDLYERQVC-----LLLLQLCSGLEHLK 123
ALK1            ---------------------------QTLEPHLALRLAVSAACGLAHLH 113
ALK2            ---------------------------TTLDTVSCLRIVLSIASGLAHLH 113
IRAK4           ---------------------------PPLSWHMRCKIAQGAANGINFLH 118
BMPR2           ---------------------------HTSDWVSSCRLAHSVTRGLAYLH 114
TGFBR2          ---------------------------HVISWEDLRKLGSSLARGIAHLH 119
ACTR2           ---------------------------NVVSWNELCHIAETMARGLAYLH 113
ACTR2B          ---------------------------NIITWNELCHVAETMSRGLSYLH 113
1B6CB           ---------------------------YTVTVEGMIKLALSTASGLAHLH 113
TGFBR1          ---------------------------YTVTVEGMIKLALSTASGLAHLH 113
ALK4            ---------------------------YTVTIEGMIKLALSAASGLAHLH 113
ALK7            ---------------------------NIVTVAGMIKLALSIASGLAHLH 113
BMPR1A          ---------------------------ATLDTRALLKLAYSAACGLCHLH 113
BMPR1B          ---------------------------TTLDAKSMLKLAYSSVSGLCHLH 113
IRAK1           ---------------------------PPLSWPQRLDILLGTARAIQFLH 119
IRAK2           ----------------------GQGGSDPLPWPQRVSICSGLLCAVEYLH 118
IRAK3           ----------------------CVGDTAPLPWHIRIGILIGISKAIHYLH 118
MISR2           --------------------------QYTSDWGSSLRMALSLAQGLAFLH 114
MYT1            ----------------------A--WGASLPEAQVWGYLRDTLLALAHLH 116
SBK             ----------------------P---QVGLPEDTVKRCVQQLGLALDFMH 114
SGK110          ----------------------ER----GLPELLVKRVVAQLAGALDFLH 113
SGK069          ----------------------P---KVGLPQPAVHRCAAQLASALEYIH 114
SGK496          -----------------------TGLKAGLTLETRLQIALDVVEGIRFLH 118
NIK             ----------------------E---QGCLPEDRALYYLGQALEGLEYLH 108
SGK424          -------------------------------------------------- 0
SURTK106        ----------------------MDGLLYDLTEKQVYHIGKQVLLALEFLQ 130
IKKE            -----------------------PENAFGLPEDEFLVVLRCVVAGMNHLR 119
TBK1            -----------------------PSNAYGLPESEFLIVLRDVVGGMNHLR 119
MOS             --------YGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLH 134
LKB1            -----------------------VPEK-RFPVCQAHGYFCQLIDGLEYLH 120
CAMKK1          ------------------------PCDKPFSEEQARLYLRDVILGLEYLH 148
CAMKK2          ------------------------PTLKPLSEDQARFYFQDLIKGIEYLH 140
PASK            -----------------------IDRHPRLDEPLASYIFRQLVSAVGYLR 122
PIM1            -----------------------ITERGALQEELARSFFWQVLEAVRHCH 122
PIM3            -----------------------ITERGALDEPLARRFFAQVLAAVRHCH 123
PIM2            -----------------------ITEKGPLGEGPSRCFFGQVVAAIQHCH 124
COT             -----------------------LESCGPMREFEIIWVTKHVLKGLDFLH 110
SCYL2           --------GNWENLPSPISPDIK---DYKLYDVETKYGLLQVSEGLSFLH 138
FUSED           ----------------------------KLPEDQVQAIAAQLVSALYYLH 114
ULK1            ----------------------------TLSEDTIRLFLQQIAGAMRLLH 115
ULK2            ----------------------------TLSEDTIRVFLHQIAAAMRILH 115
ULK3            ----------------------------ILPEKVARVFMQQLASALQFLH 116
ULK4            ----------------------------NLPEDVVREFGIDLISGLHHLH 95
IRE1            -----------------------FA---HLGLEPI-TLLQQTTSGLAHLH 110
IRE2            -----------------------LDRGG----LEPEVVLQQLMSGLAHLH 110
RNASEL          -----------------------EDVEN-EEDEFARNVLSSIFKAVQELH 108
MPSK1           -----------------------KDKGNFLTEDQILWLLLGICRGLEAIH 121
PINK1           -------------------------VNT-PSPRLAAMMLLQLLEGVDHLV 199
ALK             --------------------------PSSLAMLDLLHVARDIACGCQYLE 126
LTK             --------------------------PSPLVMRDLLQLAQDIAQGCHYLE 126
ROS             -----------------------GP---LLTLVDLVDLCVDISKGCVYLE 127
IGF1R           -----------------------NPVLAPPSLSKMIQMAGEIADGMAYLN 129
1IR3A           -----------------------NPGRPPPTLQEMIQMAAEIADGMAYLN 129
INSR            -----------------------NPGRPPPTLQEMIQMAAEIADGMAYLN 129
IRR             -----------------------NPGLPQPALGEMIQMAGEIADGMAYLA 129
1M14A           -----------------------------IGSQYLLNWCVQIAKGMNYLE 118
EGFR            -----------------------------IGSQYLLNWCVQIAKGMNYLE 118
HER2/ERBB2      -----------------------------LGSQDLLNWCMQIAKGMSYLE 118
HER4/ERBB4      -----------------------------IGSQLLLNWCVQIAKGMMYLE 118
HER3/ERBB3      -----------------------------LGPQLLLNWGVQIAKGMYYLE 118
ITK             -----------------------------FAAETLLGMCLDVCEGMAYLE 112
TEC             -----------------------------FSRDVLLSMCQDVCEGMEYLE 112
TXK             -----------------------------LRKEMLLSVCQDICEGMEYLE 112
BMX             -----------------------------LEPSQLLEMCYDVCEGMAFLE 112
1K2PA           -----------------------------FQTQQLLEMCKDVCEAMEYLE 112
BTK             -----------------------------FQTQQLLEMCKDVCEAMEYLE 112
CCK4            ------------------------LKSQPLSTKQKVALCTQVALGMEHLS 127
ROR1            --------C-SSDEDGTV--------KSSLDHGDFLHIAIQIAAGMEYLS 135
ROR2            ---------GSTDDDRTV--------KSALEPPDFVHLVAQIAAGMEYLS 135
MUSK            ---------SLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLS 143
TRKA            ---------LAGGED-VA--------PGPLGLGQLLAVASQVAAGMVYLA 133
TRKB            ---------MAEGNP-----------PTELTQSQMLHIAQQIAAGMVYLA 131
TRKC            ---------LVDGQPRQA--------KGELGLSQMLHIASQIASGMVYLA 134
DDR1            --------EGAPGDGQAA-------QGPTISYPMLLHVAAQIASGMRYLA 149
DDR2            -----------------------SSDVRTVSYTNLKFMATQIASGMKYLS 140
RYK             -----------------------NP--QAISQQDLVHMAIQIACGMSYLA 128
JAK1            ----------------------------KINLKQQLKYAVQICKGMDYLG 120
JAK2            ----------------------------RIDHIKLLQYTSQICKGMEYLG 120
JAK3            ----------------------------RLDASRLLLYSSQICKGMEYLG 120
ACK             ----------------------------HFLLGTLSRYAVQVAEGMGYLE 119
TYK2            -----------------------------IGLAQLLLFAQQICEGMAYLH 119
TNK1            --------------------------TPPLLVALLCLFLRQLAGAMAYLG 122
EPHA1           ---------------------------DQLVPGQLVAMLQGIASGMNYLS 118
EPHA10          ---------------------------GQLVAGQLMGLLPGLASAMKYLS 118
FAK             ---------------------------YSLDLASLILYAYQLSTALAYLE 117
EPHB6           ---------------------------GQFSSLQLVAMQRGVAAAMQYLS 118
EPHA2           ---------------------------GEFSVLQLVGMLRGIAAGMKYLA 119
EPHA8           ---------------------------GQFTIMQLVGMLRGVGAGMRYLS 118
EPHA6           ---------------------------GHFTVIQLVGMLRGIASGMKYLS 160
EPHB1           ---------------------------GQFTVIQLVGMLRGIAAGMKYLA 118
EPHB2           ---------------------------GQFTVIQLVGMLRGIAAGMKYLA 118
EPHB3           ---------------------------GQFTVIQLVGMLRGIAAGMKYLS 118
EPHB4           ---------------------------GQFTVIQLVGMLRGIASGMRYLA 118
EPHA7           ---------------------------GQFTVIQLVGMLRGIAAGMRYLA 118
EPHA4           ---------------------------GRFTVIQLVGMLRGIGSGMKYLS 118
EPHA3           ---------------------------AQFTVIQLVGMLRGIASGMKYLS 118
EPHA5           ---------------------------GQFTVIQLVGMLRGISAGMKYLS 118
PYK2            ---------------------------NSLKVLTLVLYSLQICKAMAYLE 117
CSK             ---------------------------SVLGGDCLLKFSLDVCEAMEYLE 112
CTK             ---------------------------ALVNTAQLLQFSLHVAEGMEYLE 110
1IEPA           ---------------------------QEVSAVVLLYMATQISSAMEYLE 114
ABL             ---------------------------QEVNAVVLLYMATQISSAMEYLE 114
ARG             ---------------------------EEVTAVVLLYMATQISSAMEYLE 114
BRK             ---------------------------KVLPVSELLDIAWQVAEGMCYLE 114
SRM             ---------------------------RALRLPPLLGFACQVAEGMSYLE 113
FRK             ---------------------------SKIHLTQQVDMAAQVASGMAYLE 113
FGR             ---------------------------QDLRLPQLVDMAAQVAEGMAYME 112
FYN             ---------------------------RALKLPNLVDMAAQVAAGMAYIE 112
SRC             ---------------------------KYLRLPQLVDMAAQIASGMAYVE 112
YES             ---------------------------KYLKLPQLVDMAAQIADGMAYIE 112
HCK             ---------------------------SKQPLPKLIDFSAQIAEGMAFIE 112
LYN             ---------------------------GKVLLPKLIDFSAQIAEGMAYIE 113
3LCK            ---------------------------IKLTINKLLDMAAQIAEGMAFIE 112
LCK             ---------------------------IKLTINKLLDMAAQIAEGMAFIE 112
BLK             ---------------------------SRLSLPRLIDMSAQIAEGMAYIE 112
FER             ---------------------------DELKLKQLVKFSLDAAAGMLYLE 114
FES             ---------------------------ARLRVKTLLQMVGDAAAGMEYLE 115
SYK             ---------------------------H-VKDKNIIELVHQVSMGMKYLE 116
ZAP70           ---------------------------EEIPVSNVAELLHQVSMGMKYLE 116
FGFR1           -----------------CYN-PSHNPEEQLSSKDLVSCAYQVARGMEYLA 138
FGFR2           -----------------SYD-INRVPEEQMTFKDLVSCTYQLARGMEYLA 138
FGFR3           -----------------SFD-TCKPPEEQLTFKDLVSCAYQVARGMEYLA 138
FGFR4           -----------------SPD-GPRSSEGPLSFPVLVSCAYQVARGMQYLE 138
RET             --------------SRNSSS-LDHPDERALTMGDLISFAWQISQGMQYLA 143
TIE1            -----------------AFA-REHGTASTLSSRQLLRFASDAANGMQYLS 133
1FVRA           -----------------AFA-IANSTASTLSSQQLLHFAADVARGMDYLS 133
TIE2            -----------------AFA-IANSTASTLSSQQLLHFAADVARGMDYLS 133
FLT1            GFQED----KSLSDVEEEE-DSDGFYKEPITMEDLISYSFQVARGMEFLS 188
KDR             GFVEE----KSLSDVEEEE-APEDLYKDFLTLEHLICYSFQVAKGMEFLA 187
KDR_AVE         --------------------------KDFLTLEHLICYSFQVAKGMEFLA 130
FLT4            FSKTEGGARRASPDQ-----EAEDLWLSPLTMEDLVCYSFQVARGMEFLA 185
FMS             ----------SSNDSFSEQ-DLDKEDGRPLELRDLLHFSSQVAQGMAFLA 189
FLT3            SFHSEDEIE-----YENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLE 194
KIT             ADKRRSVRIGSYIERDVTPA-IMEDDELALDLEDLLSFSYQVAKGMAFLA 196
PDGFRA          YDRPASYKKKSMLDSEVKN-LLSDDNSEGLTLLDLLSFTYQVARGMEFLA 218
PDGFRB          YMAPYDNYVPSAPERTCRA--TLINESPVLSYMDLVGFSYQVANGMEFLA 219
MER             ---------------------------KHIPLQTLLKFMVDIALGMEYLS 129
AXL             ---------------------------VYLPTQMLVKFMADIASGMEYLS 129
TYRO3           ---------------------------FNLPLQTLIRFMVDIACGMEYLS 130
MET             ---------------------------HNPTVKDLIGFGLQVAKAMKYLA 119
RON             ---------------------------RNPTVKDLISFGLQVARGMEYLA 119
HH498           -------------------------------LQSKLIIAVDVAKGMEYLH 116
LZK             ----------------------------KITPRLLVDWSTGIASGMNYLH 104
DLK             ----------------------------PVTPSLLVDWSMGIAGGMNYLH 104
MLK1            ----------------------------RIPPDILVNWAVQIARGMNYLH 114
MLK3            ----------------------------RVPPHVLVNWAVQIARGMHYLH 114
MLK2            ----------------------------RVPPHVLVNWAVQVARGMNYLH 114
MLK4            --------------------APGPRRARRIPPHVLVNWAVQIARGMLYLH 129
ZAK             -------------------------------MDHIMTWATDVAKGMHYLH 107
TAK1            -----------------------------YTAAHAMSWCLQCSQGVAYLH 110
KSR1            -------------------------------INKTRQIAQEIIKGMGYLH 113
KSR2            -------------------------------VNKTRQIAQEIVKGMGYLH 113
ARAF            -------------------------------MVQLIDVARQTAQGMDYLH 112
RAF1            -------------------------------MFQLIDIARQTAQGMDYLH 112
BRAF            -------------------------------MIKLIDIARQTAQGMDYLH 112
LRRK2           -------------------------------RTLQHRIALHVADGLRYLH 108
ANKRD3          -----------------------------LPWDLRFRIIHETAVGMNFLH 112
SGK288          -----------------------------LCWKLRFRIIHETSLAMNFLH 111
RIPK2           -----------------------------VAWPLRFRILHEIALGVNYLH 119
RIPK3           -------------------------------WPLLCRLLKEVVLGMFYLH 112
MLKL            -------------------------------LGKRMVLVLGAARGLYRLH 114
ANPA            -------------------------------WMFRYSLTNDIVKGMLFLH 117
ANPB            -------------------------------WMFRYSLINDLVKGMAFLH 117
CYGD            -------------------------------WMFKSSLLLDLIKGIRYLH 126
CYGF            -------------------------------WMFKSSLLLDLIKGMKYLH 131
TBCK            ---------------------------KPVSCSTVLCIAFEVLQGLQYMN 91
ERK1            -------------LLKSQ----------QLSNDHICYFLYQILRGLKYIH 117
3ERK            -------------LLKTQ----------HLSNDHICYFLYQILRGLKYIH 117
ERK2            -------------LLKTQ----------HLSNDHICYFLYQILRGLKYIH 117
ERK5            -------------IIHSSQ---------PLTLEHVRYFLYQLLRGLKYMH 120
1JNK            -------------VIQM-----------ELDHERMSYLLYQMLCGIKHLH 118
1PMNA           -------------VIQM-----------ELDHERMSYLLYQMLCGIKHLH 118
JNK3            -------------VIQM-----------ELDHERMSYLLYQMLCGIKHLH 118
JNK1            -------------VIQM-----------ELDHERMSYLLYQMLCGIKHLH 118
JNK2            -------------VIHM-----------ELDHERMSYLLYQMLCGIKHLH 118
1P38            -------------IVKCQ----------KLTDDHVQFLIYQILRGLKYIH 119
P38A            -------------IVKCQ----------KLTDDHVQFLIYQILRGLKYIH 119
P38B            -------------IVKCQAGAH--QGARLALDEHVQFLVYQLLRGLKYIH 127
P38D            -------------IMGM-----------EFSEEKIQYLVYQMLKGLKYIH 118
P38G            -------------LMKHE----------KLGEDRIQFLVYQMLKGLRYIH 119
NLK             -------------IIVSPQ---------PLSSDHVKVFLYQILRGLKYLH 119
ERK7            -------------VIRKGG---------LLQDVHVRSIFYQLLRATRFLH 136
ERK3            -------------VLEQG----------PLLEEHARLFMYQLLRGLKYIH 125
ERK4            -------------LLEQG----------TLAEEHAKLFMYQLLRGLKYIH 122
ICK             -------------LIKERN--------KLFPESAIRNIMYQILQGLAFIH 114
MAK             -------------LMKDRN--------KLFPESVIRNIMYQILQGLAFIH 114
PCTAIRE1        -------------YLDDCG--------NIINMHNVKLFLFQLLRGLAYCH 114
PCTAIRE2        -------------YMDDCG--------NIMSMHNVKLFLYQILRGLAYCH 114
PCTAIRE3        -------------YLDHCG--------NLMSMHNVKIFMFQLLRGLAYCH 114
PFTAIRE1        -------------YMDKHP--------GGLHPDNVKLFLFQLLRGLSYIH 114
PFTAIRE2        -------------YMSQHP--------GGLHPHNVRLFMFQLLRGLAYIH 114
CDC2            -------------YLDSIP------PGQYMDSSLVKSYLYQILQGIVFCH 117
1HCL            -------------FMDASA-------LTGIPLPLIKSYLFQLLQGLAFCH 112
CDK2            -------------FMDASA-------LTGIPLPLIKSYLFQLLQGLAFCH 116
CDK3            -------------YMDSTP-------GSELPLHLIKSYLFQLLQGVSFCH 116
CDK5            -------------YFDSCN--------GDLDPEIVKSFLFQLLKGLGFCH 115
CDK7            -------------IIKDNS--------LVLTPSHIKAYMLMTLQGLEYLH 118
CDK4            -------------YLDKAP-------PPGLPAETIKDLMRQFLRGLDFLH 127
1BLXA           -------------YLDKVP-------EPGVPTETIKDMMFQLLRGLDFLH 125
CDK6            -------------YLDKVP-------EPGVPTETIKDMMFQLLRGLDFLH 125
PITSLRE         -------------LMETMK--------QPFLPGEVKTLMIQLLRGVKHLH 117
CDK10           -------------LLENMP--------TPFSEAQVKCIVLQVLRGLQYLH 117
CDK9            -------------LLSNVL--------VKFTLSEIKRVMQMLLNGLYYIH 123
CHED            -------------LLESGL--------VHFYENHIKSFMRQLMEGLDYCH 125
CRK7            -------------LLESGL--------VHFSEDHIKSFMKQLMEGLEYCH 125
CCRK            -------------VVRHAQ--------RPLAQAQVKSYLQMLLKGVAFCH 116
CDK11           -------------IIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLH 124
CDK8            -------------IIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLH 124
IKKA            --------------------------CCGLKESQILSLLSDIGSGIRYLH 122
IKKB            --------------------------CCGLREGAILTLLSDIASALRYLH 123
1PHK            ----------------------------TLSEKETRKIMRALLEVICALH 123
PHKG1           ----------------------------TLSEKETRKIMRALLEVICTLH 123
PHKG2           ----------------------------ALSEKETRSIMRSLLEAVSFLH 122
CAMK2A          ----------------------------YYSEADASHCIQQILEAVLHCH 115
CAMK2B          ----------------------------YYSEADASHCIQQILEAVLHCH 115
CAMK2G          ----------------------------YYSEADASHCIHQILESVNHIH 115
CAMK2D          ----------------------------YYSEADASHCIQQILESVNHCH 115
CASK            --------------------------GFVYSEAVASHYMRQILEALRYCH 122
1IA8A           ----------------------------GMPEPDAQRFFHQLMAGVVYLH 111
CHK1            ----------------------------GMPEPDAQRFFHQLMAGVVYLH 114
CLK1            --------------------------FLPFRLDHIRKMAYQICKSVNFLH 120
CLK4            --------------------------FLPFQIDHIRQMAYQICQSINFLH 119
CLK2            --------------------------YLPYPIHQVRHMAFQLCQAVKFLH 120
CLK3            --------------------------FQPYPLPHVRHMAYQLCHALRFLH 120
MAP2K5          -----------------------------MPEHVLGRIAVAVVKGLTYLW 110
MAP2K3          ----------------------LDK-NMTIPEDILGEIAVSIVRALEHLH 118
MAP2K6          ----------------------IDK-GQTIPEDILGKIAVSIVKALEHLH 118
MAP2K4          ----------------------YSVLDDVIPEEILGKITLATVKALNHLK 119
MAP2K7          ----------------------Q----GPIPERILGKMTVAIVKALYYLK 115
MAP2K1          ----------------------LKK-AGRIPEQILGKVSIAVIKGLTYLR 114
MAP2K2          ----------------------LKE-AKRIPEEILGKVSIAVLRGLAYLR 114
CDKL5           ------------------LLEEMPNG---VPPEKVKSYIYQLIKAIHWCH 115
CDKL1           ------------------ELDRYQRG---VPEHLVKSITWQTLQAVNFCH 115
CDKL4           ------------------ELERNPNG---VADGVIKSVLWQTLQALNFCH 115
CDKL2           ------------------DLELFPNG---LDYQVVQKYLFQIINGIGFCH 115
CDKL3           ------------------ELQHYCHG---LESKRLRKYLFQILRAIDYLH 114
1I09B           ------------------VARHYSRAKQTLPVIYVKLYMYQLFRSLAYIH 118
GSK3B           ------------------VARHYSRAKQTLPVIYVKLYMYQLFRSLAYIH 118
1J1BA           ------------------VARHYSRAKQTLPVIYVKLYMYQLFRSLAYIH 118
GSK3A           ------------------VARHFTKAKLTIPILYVKVYMYQLFRSLAYIH 118
LATS1           ---------------------------GIFPESLARFYIAELTCAVESVH 116
LATS2           ----------------------------VFPEHLARFYIAELTLAIESVH 116
NDR1            ---------------------------DTLTEEETQFYIAETVLAIDSIH 116
NDR2            ---------------------------DTLTEEETQFYISETVLAIDAIH 116
MAST1           ---------------------------GALPVEMARMYFAETVLALEYLH 116
MAST4           ---------------------------GPLPVDMARMYFAETVLALEYLH 116
MAST2           ---------------------------GALPVDMVRLYFAETVLALEYLH 116
MAST3           ---------------------------GPLPVDMARLYFAETVLALEYLH 116
MRCKA           ---------------------------DRLPEDMARFYLAEMVIAIDSVH 117
MRCKB           ---------------------------DKLPEDMARFYIGEMVLAIDSIH 117
DMPK2           ---------------------------DRLPPELAQFYLAEMVLAIHSLH 117
DMPK1           ---------------------------ERIPAEMARFYLAEIVMAIDSVH 117
ROCK1           -----------------------------VPEKWARFYTAEVVLALDAIH 115
ROCK2           -----------------------------VPEKWAKFYTAEVVLALDAIH 115
CRIK            ---------------------------DQLDENLIQFYLAELILAVHSVH 117
MASTL           ---------------------------GYFDEEMAVKYISEVALALDYLH 114
1O6LA           ---------------------------RVFTEERARFYGAEIVSALEYLH 116
AKT2            ---------------------------RVFTEERARFYGAEIVSALEYLH 116
AKT1            ---------------------------RVFSEDRARFYGAEIVSALDYLH 116
AKT3            ---------------------------RVFSEDRTRFYGAEIVSALDYLH 116
MSK1            ---------------------------ERFTEHEVQIYVGEIVLALEHLH 121
MSK2            ---------------------------QYFKEAEVRVYGGEIVLALEHLH 121
P70S6K          ---------------------------GIFMEDTACFYLAEISMALGHLH 120
P70S6KB         ---------------------------GIFLEDTACFYLAEITLALGHLH 120
RSK1            ---------------------------VMFTEEDVKFYLAELALALDHLH 118
RSK3            ---------------------------VMFTEEDVKFYLAELALGLDHLH 118
RSK2            ---------------------------VMFTEEDVKFYLAELALALDHLH 118
RSK4            ---------------------------VLFTEEDVKFYLAELALALDHLH 118
1FOTA           ---------------------------QRFPNPVAKFYAAEVCLALEYLH 116
1CDKA           ---------------------------GRFSEPHARFYAAQIVLTFEYLH 116
PKACA           ---------------------------GRFSEPHARFYAAQIVLTFEYLH 116
PKACB           ---------------------------GRFSEPHARFYAAQIVLTFEYLH 116
PKACG           ---------------------------GRFSEPHACFYAAQVVLAVQYLH 116
PRKX            ---------------------------GRFSSTTGLFYSAEIICAIEYLH 116
PRKY            ---------------------------GHFSSTTGLFYSAEIICAIEYLH 116
PKCA            ---------------------------GKFKEPQAVFYAAEISIGLFFLH 117
PKCB            ---------------------------GRFKEPHAVFYAAEIAIGLFFLQ 117
PKCG            ---------------------------GKFKEPHAAFYAAEIAIGLFFLH 122
PKCE            ---------------------------RKFDEPRSRFYAAEVTSALMFLH 117
PKCH            ---------------------------RRFDEARARFYAAEIISALMFLH 117
PKCD            ---------------------------GRFELYRATFYAAEIMCGLQFLH 117
PKCT            ---------------------------HKFDLSRATFYAAEIILGLQFLH 117
PKCI            ---------------------------RKLPEEHARFYSAEISLALNYLH 117
PKCZ            ---------------------------RKLPEEHARFYAAEICIALNFLH 117
PKN1            ---------------------------DVFSEPRAIFYSACVVLGLQFLH 118
PKN2            ---------------------------DVFSEPRAVFYAACVVLGLQYLH 118
PKN3            ---------------------------DVFPEPQARFYVACVVLGLQFLH 118
SGK             ---------------------------RCFLEPRARFYAAEIASALGYLH 117
SGK2            ---------------------------RRFLEPRARFYAAEVASAIGYLH 117
SGK3            ---------------------------RSFPEHRARFYAAEIASALGYLH 117
PKG1            ---------------------------GSFEDSTTRFYTACVVEAFAYLH 117
PKG2            ---------------------------GSFDEPTSKFCVACVTEAFDYLH 116
AURB            -------------------------S-CTFDEQRTATIMEELADALMYCH 116
AURC            -------------------------S-EKLDEQRTATIIEEVADALTYCH 116
AURA            -------------------------L-SKFDEQRTATYITELANALSYCH 116
AURORA2_AVE     -------------------------L-SKFDEQRTATYITELANALSYCH 116
PLK1            -------------------------R-KALTEPEARYYLRQIVLGCQYLH 116
PLK2            -------------------------R-KVLTEPEVRYYLRQIVSGLKYLH 116
PLK3            -------------------------R-HTLLEPEVRYYLRQILSGLKYLH 116
PLK4            -------------------------RVKPFSENEARHFMHQIITGMLYLH 117
NEK11           -------------------------G-KIFPENQIIEWFIQLLLGVDYMH 122
YANK1           ---------------------------VHFKEETVKLFICELVMALDYLQ 116
YANK2           ---------------------------VHFTEGTVKLYICELALALEYLQ 116
YANK3           ---------------------------VQFSEDTVRLYICEMALALDYLR 116
SGK494          ---------------------------GCFPEASIRLFAAELVLVLCYLH 115
DOMAIN2_MSK1    ------------------------K--KHFSETEASYIMRKLVSAVSHMH 111
DOMAIN2_MSK2    ------------------------K--RHFSESEASQILRSLVSAVSFMH 105
DOMAIN2_RSK1    ------------------------Q--RYFSEREASDVLCTITKTMDYLH 110
DOMAIN2_RSK2    ------------------------Q--KFFSEREASAVLFTITKTVEYLH 110
DOMAIN2_RSK3    ------------------------Q--KFFSEREASFVLHTIGKTVEYLH 110
DOMAIN2_RSK4    ------------------------Q--KCFSEREASDILYVISKTVDYLH 110
DRAK1           ------------------------DREEAFKEKDVQRLMRQILEGVHFLH 118
DRAK2           ------------------------ELAEMVSENDVIRLIKQILEGVYYLH 118
1JKSA           ------------------------K--ESLTEEEATEFLKQILNGVYYLH 119
DAPK1           ------------------------K--ESLTEEEATEFLKQILNGVYYLH 119
DAPK3           ------------------------K--ESLTEDEATQFLKQILDGVHYLH 119
DAPK2           ------------------------K--ESLSEEEATSFIKQILDGVNYLH 119
SGK085          ------------------------E-SYNLTELDTILFMKQICEGIRHMH 114
CAMLCK          ------------------------E-KYHLTELDVVLFTRQICEGVHYLH 114
SKMLCK          ------------------------E-DYHLTEVDTMVFVRQICDGILFMH 114
SMMLCK          ------------------------E-DFELTERECIKYMRQISEGVEYIH 114
1KOBA           ------------------------E-DYKMSEAEVINYMRQACEGLKHMH 114
1TKIA           ------------------------S-AFELNEREIVSYVHQVCEALQFLH 113
TTN             ------------------------S-AFELNEREIVSYVHQVCEALQFLH 113
PKD1            ------------------------SEKGRLPEHITKFLITQILVALRHLH 116
PKD3            ------------------------SEKSRLPERITKFMVTQILVALRNLH 116
PKD2            ------------------------SEKGRLPERLTKFLITQILVALRHLH 116
PSKH1           ------------------------K--GSFTERDATRVLQMVLDGVRYLH 113
PSKH2           ------------------------Q--GSFTERDAVRILQMVADGIRYLH 113
CAMK1A          ------------------------K--GFYTERDASRLIFQVLDAVKYLH 114
CAMK1D          ------------------------K--GFYTEKDASTLIRQVLDAVYYLH 114
CAMK1B          ------------------------R--GSYTEKDASHLVGQVLGAVSYLH 114
CAMK1G          ------------------------R--GVYTEKDASLVIQQVLSAVKYLH 113
CAMK4           ------------------------K--GYYSERDAADAVKQILEAVAYLH 111
DCAMKL1         ------------------------T--NKYTERDASGMLYNLASAIKYLH 114
DCAMKL2         ------------------------S--TKYTERDGSAMVYNLANALRYLH 114
DCAMKL3         ------------------------S--VKFPEPDAALMIMDLCKALVHMH 114
CHK2            ------------------------N--KRLKEATCKLYFYQMLLAVQYLH 120
MAPKAPK2        ------------------------RGDQAFTEREASEIMKSIGEAIQYLH 115
MAPKAPK3        ------------------------RGDQAFTEREAAEIMRDIGTAIQFLH 115
MAPKAPK5        ------------------------H--RHFTEKQASQVTKQIALALRHCH 119
MNK1            ------------------------Q--KHFNEREASRVVRDVAAALDFLH 115
MNK2            ------------------------R--RHFNELEASVVVQDVASALDFLH 114
VACAMKL         ------------------------Q--GYYSERDTSNVVRQVLEAVAYLH 114
GCK             -------------------------GPL--EERQIAYVCRERLKGLHHLH 113
KHS1            -------------------------GPL--SELQIAYVCRETLQGLAYLH 113
KHS2            -------------------------GPL--SELQIAYVSRETLQGLYYLH 113
HPK1            -------------------------GSL--SELQISYVCREVLQGLAYLH 113
MST1            -------------------------KTL--TEDEIATILQSTLKGLEYLH 112
MST2            -------------------------KTL--IEDEIATILKSTLKGLEYLH 112
MST3            -------------------------GPL--DETQIATILREILKGLDYLH 113
YSK1            -------------------------GPL--EETYIATILREILKGLDYLH 113
MST4            -------------------------GPF--DEFQIATMLKEILKGLDYLH 113
LOK             -------------------------RGL--TEPQIQVVCRQMLEALNFLH 114
SLK             -------------------------RPL--TESQIQVVCKQTLDALNYLH 114
MAP3K4          --------------------------GL--QEHVIRLYSKQITIAINVLH 113
MAP3K2          -------------------------GAL--TENGTRKYTRQILEGVHYLH 120
MAP3K3          -------------------------GAL--TESVTRKYTRQILEGMSYLH 120
MAP3K8          -------------------------GPL--PEMVFCKYTKQILQGVAYLH 118
MAP3K5          -------------------------GPLKDNEQTIGFYTKQILEGLKYLH 121
MAP3K7          -------------------------GPM--KEPTIKFYTKQILEGLKYLH 112
MAP3K6          -------------------------GPLKDNESTISFYTRQILQGLGYLH 111
PAK1            --------------------------CM--DEGQIAAVCRECLQALEFLH 112
PAK3            --------------------------CM--DEGQIAAVCRECLQALDFLH 112
PAK2            -------------------------ACM--DEAQIAAVCRECLQALEFLH 113
PAK4            --------------------------RM--NEEQIAAVCLAVLQALSVLH 112
PAK5            --------------------------RM--NEEQIATVCLSVLRALSYLH 112
PAK6            --------------------------RL--NEEQIATVCEAVLQALAYLH 112
OSR1            -------------------------GVL--DESTIATILREVLEGLEYLH 122
STLK3           -------------------------GVL--EEAIIATILKEVLEGLDYLH 122
TAO1            -------------------------KPL--QEVEIAAITHGALQGLAYLH 116
TAO3            -------------------------KPL--QEVEIAAITHGALHGLAYLH 116
TAO2            -------------------------KPL--QEVEIAAVTHGALQGLAYLH 116
MYO3A           -------------------------ERM--SEPLIAYILHEALMGLQHLH 122
MYO3B           -------------------------QRL--DEAMISYILYGALLGLQHLH 122
ZC1/HGK         -------------------------NTL--KEDWIAYISREILRGLAHLH 121
ZC3/MINK        -------------------------NAL--KEDCIAYICREILRGLAHLH 121
ZC2/TNIK        -------------------------NTL--KEEWIAYICREILRGLSHLH 121
ZC4/NRK         -------------------------QSL--KEDWIAYICREILQGLAHLH 145
MAP3K1          -------------------------GAF--KESVVINYTEQLLRGLSYLH 119
GAK             -------------------------GP--LSCDTVLKIFYQTCRAVQHMH 124
SGK495          -------------------------KR--LSERETVVIFYDVVRVVEALH 32
TRB1            -------------------------KR--LREEEAARLFKQIVSAVAHCH 99
TRB2            -------------------------KK--LREEEAARLFYQIASAVAHCH 104
TRB3            -------------------------HR--IPEPEAAVLFRQMATALAHCH 102
SSTK            -------------------------GR--IPGVQARDLFAQIAGAVRYLH 116
TSSK3           -------------------------GP--LPESRAKALFRQMVEAIRYCH 117
TSSK1           -------------------------GA--LHEDEARKKFHQLSLAIKYCH 117
TSSK2           -------------------------GA--LHEDVARKMFRQLSSAVKYCH 117
TSSK4           -------------------------GA--CSEPLAGKWFSQLTLGIAYLH 116
HUNK            -------------------------KR--LEESEARRYIRQLISAVEHLH 118
SNRK            -------------------------EE-GLNEDLAKKYFAQIVHAISYCH 116
NIM1            -------------------------GK--LSEPESKLIFSQIVSAVKHMH 115
MELK            -------------------------DR--LSEEETRVVFRQIVSAVAYVH 114
BRSK1           -------------------------GR--LTPKEARKFFRQIVSALDFCH 115
BRSK2           -------------------------GR--LTPKEARKFFRQIISALDFCH 115
MARK1           -------------------------GR--MKEKEARAKFRQIVSAVQYCH 115
MARK2           -------------------------GR--MKEKEARAKFRQIVSAVQYCH 115
MARK3           -------------------------GR--MKEKEARSKFRQIVSAVQYCH 115
MARK4           -------------------------GR--MKEKEARAKFRQIVSAVHYCH 115
QIK             -------------------------GR--LNESEARRKFWQILSAVDYCH 115
SIK             -------------------------GH--LSENEARKKFWQILSAVEYCH 115
QSK             -------------------------GR--MAEKEARRKFKQIVTAVYFCH 115
AMPKA1          -------------------------GR--LDEKESRRLFQQILSGVDYCH 116
AMPKA2          -------------------------GR--VEEMEARRLFQQILSAVDYCH 116
NUAK1           -------------------------RR--LSERETRHFFRQIVSAVHYCH 116
NUAK2           -------------------------QQ--LSEREARHFFRQIVSAVHYCH 115
BIKE            -------------------------LQTGFTEPEVLQIFCDTCEAVARLH 120
AAK1            -------------------------LQTGFTENEVLQIFCDTCEAVARLH 121
LIMK1           -----------------------------YPWSQRVSFAKDIASGMAYLH 114
LIMK2           ----------------------------PFPWQQKVRFAKGIASGMAYLH 113
TESK1           ----------------------------PLSWPVRLHLALDIARGLRYLH 111
TESK2           ----------------------------HLPWTVRVKLAYDIAVGLSYLH 91
WNK1            ----------------------------VMKIKVLRSWCRQILKGLQFLH 119
WNK3            ----------------------------VMKPKVLRSWCRQILKGLQFLH 119
WNK2            ----------------------------VMKPKVLRSWCRQILKGLLFLH 119
WNK4            ----------------------------EMKPRVLQRWSRQILRGLHFLH 119
NEK10           --------------------------HHHFTEERLWKIFIQLCLALRYLH 128
NEK6            --------------------------KRLIPERTVWKYFVQLCSAVEHMH 120
NEK7            --------------------------KRLIPERTVWKYFVQLCSALEHMH 120
NEK2            --------------------------RQYLDEEFVLRVMTQLTLALKECH 121
NEK1            --------------------------GVLFQEDQILDWFVQICLALKHVH 117
NEK5            --------------------------GVLFSEDQILGWFVQISLGLKHIH 117
NEK3            --------------------------GKLFPEDMILNWFTQMCLGVNHIH 116
NEK4            --------------------------GQLLPENQVVEWFVQIAMALQYLH 118
NEK8            --------------------------NSLLEEETILHFFVQILLALHHVH 117
NEK9            --------------------------DKLFEEEMVVWYLFQIVSAVSCIH 117
NRBP1           --------------------------HKTMNEKAWKRWCTQILSALSYLH 128
NRBP2           --------------------------HKAMNARAWKRWCTQILSALSFLH 128
CLIK1           -----------------------------DPATNKSFMLQ-LTSAIAFLH 151
CLIK1L          -----------------------------NRKTNTSFMLQ-LSSALAFLH 149
STK33           -----------------------------FSENETRWIIQSLASAIAYLH 115
DOMAIN2_GCN2    -------------------HLSHSGPIPV---HQLRRYTAQLLSGLDYLH 138
SCYL1           ---------------------VEAGGLKE---LEISWGLHQIVKALSFLV 104
SCYL3           ------------------------ETLSS---AEVCAGIYDILLALIFLH 91
DOMAIN2_JAK1    -------------------------VLTT---PWKFKVAKQLASALSYLE 124
DOMAIN2_TYK2    -------------------------HVPM---AWKMVVAQQLASALSYLE 138
DOMAIN2_JAK2    -------------------------CINI---LWKLEVAKQLAWAMHFLE 121
DOMAIN2_JAK3    -------------------------LVPA---SWKLQVVKQLAYALNYLE 119
ILK             ----------------------TNFVVDQ---SQAVKFALDMARGMAFLH 117
LRRK1           --------------------ARDSSFIPLGH-MLTQKIAYQIASGLAYLH 137
PBK             -------------------YKASQDPFPA---AIILKVALNMARGLKYLH 127
WEE1            --------------------YRIMSYFKE---AELKDLLLQVGRGLRYIH 120
WEE1B           --------------------TKSGNHFEE---PKLKDILLQISLGLNYIH 120
SGK071          --------------------RKAKKIIDS---EWMQNVLGQVLDALEYLH 122
PIK3R4          -------------------RISTRPFLNN---IEKRWIAFQILTAVDQAH 115
MSSK1           --------------------------LPV---PCVKSIVRQVLHGLDYLH 125
SRPK1           --------------------------LPL---PCVKKIIQQVLQGLDYLH 125
SRPK2           --------------------------LPV---RCVKSIIRQVLQGLDYLH 125
RSKL1           ---------------------ASRFYIPE---GCIQRWAAEMVVALDALH 100
RSKL2           -------------------CGRATWSVRE---EQVKQWAAEMLVALEALH 252
SGK396          --------------------VQANMPLNS---EETLKVMKGVAQGLHTLH 114
VRK1            -----------------------AKRFSR---KTVLQLSLRILDILEYIH 133
VRK2            -------------------ISGQNGTFKK---STVLQLGIRMLDVLEYIH 130
VRK3            ---------------------SPKHVLSE---RSVLQVACRLLDALEFLH 78
BUB1            -------------------KNTPEKVMPQ---GLVISFAMRMLYMIEQVH 123
BUBR1           -------------------LLQHSEYITH---EITVLIIYNLLTIVEMLH 122
SGK196          -------------------TLNLSKYQNVNTWQHRLELAMDYVSIINYLH 113
SGK493          ------------------------QLLQTS-WEDRFRICLSLGRLLHHLA 127
                                                                  

DYRK1A          TPEL---------SI-IHCD-LKPENILLCNPK----------------- 141
DYRK1B          TPEL---------SI-IHCD-LKPENILLCNPK----------------- 141
DYRK2           K--N---------RI-IHCD-LKPENILLKQQG----------------- 139
DYRK3           K--N---------KI-IHCD-LKPENILLKHHG----------------- 139
DYRK4           V--E---------KI-IHCD-LKPENIVLYQKG----------------- 139
HIPK1           S--L---------GL-IHAD-LKPENIMLVDPV----------------- 138
HIPK2           S--L---------GL-IHAD-LKPENIMLVDPS----------------- 138
HIPK3           S--L---------GL-IHAD-LKPENIMLVDPV----------------- 138
HIPK4           E--L---------AI-IHAD-LKPENIMLVDQT----------------- 138
PRP4            R--C---------NI-LHAD-IKPDNILVNESK----------------- 141
MOK             R--N---------GI-FHRD-VKPENILIKQD------------------ 136
1A6O            S--Q---------GI-MHRD-VKPHNVMIDHEL----------------- 130
1LPUA           S--Q---------GI-MHRD-VKPHNVMIDHEL----------------- 130
CK2A1           S--M---------GI-MHRD-VKPHNVMIDHEH----------------- 130
CK2A1-RS        S--M---------GI-MHRD-VKPHNVMIDHEH----------------- 130
CK2A2           S--K---------GI-MHRD-VKPHNVMIDHQQ----------------- 130
HSER            S--S---------KTEVHGR-LKSTNCVVDSRM----------------- 138
SLOB            D--K---------GF-PYGH-LHASNVMLDGDT-CRLLD----------- 157
CDC7            Q--F---------GI-VHRD-VKPSNFLYNRRL----------------- 132
1CSN            E--K---------SL-VYRD-IKPDNFLIGRPN-S--------------- 133
CK1G1           S--K---------NL-IYRD-VKPENFLIGRQG-N--------------- 134
CK1G3           S--K---------NL-IYRD-VKPENFLIGRPR-N--------------- 133
CK1G2           T--K---------SL-IYRD-VKPENFLVGRPG-T--------------- 133
CK1A            T--K---------NF-IHRD-IKPDNFLMGIG------------------ 131
CK1A2           T--K---------NF-LHRD-IKPDNFLMGTG------------------ 131
1CKJA           S--K---------NF-IHRD-VKPDNFLMGLG------------------ 131
CK1D            S--K---------NF-IHRD-VKPDNFLMGLG------------------ 131
CK1E            S--K---------NF-IHRD-VKPDNFLMGLG------------------ 131
TTBK1           S--V---------GF-LHRD-IKPSNFAMGRLP----------------- 133
TTBK2           S--V---------GF-LHRD-IKPSNFAMGRFP----------------- 133
TLK1            EIKP---------PI-IHYD-LKPGNILLVDGT----------------- 143
TLK2            EIKP---------PI-IHYD-LKPGNILLVNGT----------------- 143
GPRK4           R--E---------RI-VYRD-LKPENILLDDRG----------------- 138
GPRK6           R--E---------RI-VYRD-LKPENILLDDHG----------------- 138
GPRK5           R--E---------NT-VYRD-LKPENILLDDYG----------------- 138
RHOK            Q--R---------RI-VYRD-LKPENVLLDNDG----------------- 140
GPRK7           E--L---------GI-VYRD-MKPENGLLDDLG----------------- 138
BARK1           N--R---------FV-VYRD-LKPANILLDEHG----------------- 139
BARK2           N--R---------FV-VYRD-LKPANILLDEHG----------------- 139
TTK             Q--H---------GI-VHSD-LKPANFLIVDG------------------ 134
RIPK1           G--K---------GV-IHKD-LKPENILVDNDF----------------- 134
HASPIN          A-SL---------RF-EHRD-LHWGNVLLKKTS-LKKLHYTLNGKSSTIP 194
GCN2            EK------------GMIHRD-LKPVNIFLDS----DD------------- 271
HRI             NM------------GIVHRD-LKPRNIFLHGP---DQ------------- 289
KIS             HE------------GYVHAD-LKPRNILWSAEN---E------------- 149
PDK1            GK------------GIIHRD-LKPENILLNE----DM------------- 136
PKR             SK------------KLIHRD-LKPSNIFLVD----TK------------- 160
PEK             SK------------GLMHRD-LKPSNIFFTM----DD------------- 357
PRPK            DE------------DLIHGD-LTTSNMLLKPPL-EQL------------- 145
DOMAIN2_OBSCN   NQ------------HILHLD-LRSENMIITE-----YN------------ 132
DOMAIN2_SPEG    GH------------HVLHLD-IKPDNLLLAP-----DN------------ 132
LMR1            RN------------NFVHSD-LALRNCLLTA-----DL------------ 141
LMR2            KL------------HFLHSD-LALRNCFLTS-----DL------------ 141
LMR3            SH------------NYVHSD-LALRNCLLTS-----DL------------ 146
SGK307          FQ------------GFIHRS-LSSYAVHIIS-----PG------------ 49
STLK5           HM------------GYVHRS-VKASHILISV-----DG------------ 139
STLK6           QN------------GCIHRS-IKASHILISG-----DG------------ 139
STLK6-RS        QN------------GCIHRS-IKASHILISG-----DG------------ 139
OBSCN           SH------------GVLHLD-IKPSNILMVHP---ARE------------ 134
SPEG            QS------------HVLHLD-VKPENLLVWDGA-AGEQ------------ 135
TRAD            NC------------RVAHLD-IKPENLLIDL-R-IPVP------------ 135
TRIO            NC------------RIAHLD-LKPENILVDE-S-LAKP------------ 135
SGK223          EH------------GIIHRD-LCLENLLLVH-----CT------------ 140
SGK269          PY------------HVTHCD-LRLENLLLVH------------------- 141
ALK1            VEIF-GTQG---KPAIAHRD-FKSRNVLVKSNL----------------- 141
ALK2            IEIF-GTQG---KPAIAHRD-LKSKNILVKKNG----------------- 141
IRAK4           ENHH------------IHRD-IKSANILLDEAF----------------- 138
BMPR2           TELPRGDHY---KPAISHRD-LNSRNVLVKNDG----------------- 143
TGFBR2          SDHT-PC-GRP-KMPIVHRD-LNSSNILVKNDL----------------- 148
ACTR2           EDIP-GLKD-GHKPAISHRD-IKSKNVLLKNNL----------------- 143
ACTR2B          EDVP-WCRGEGHKPSIAHRD-FKSKNVLLKSDL----------------- 144
1B6CB           MEIV-GTQG---KPAIAHRD-LKSKNILVKKNG----------------- 141
TGFBR1          MEIV-GTQG---KPAIAHRD-LKSKNILVKKNG----------------- 141
ALK4            MEIV-GTQG---KPGIAHRD-LKSKNILVKKNG----------------- 141
ALK7            MEIV-GTQG---KPAIAHRD-IKSKNILVKKCE----------------- 141
BMPR1A          TEIY-GTQG---KPAIAHRD-LKSKNILIKKNG----------------- 141
BMPR1B          TEIF-STQG---KPAIAHRD-LKSKNILVKKNG----------------- 141
IRAK1           QD----------SPSLIHGD-IKSSNVLLDERL----------------- 141
IRAK2           GL------------EIIHSN-VKSSNVLLDQN---L-------------- 138
IRAK3           NVQ---------PCSVICGS-ISSANILLDDQ---F-------------- 141
MISR2           EERW---QNGQYKPGIAHRD-LSSQNVLIRED---G-------------- 143
MYT1            SQ------------GLVHLD-VKPANIFLGPR---G-------------- 136
SBK             GR------------QLVHRD-IKPENVLLFDRE-CR-------------- 136
SGK110          SR------------GLVHAD-VKPDNVLVFDPV-CS-------------- 135
SGK069          AR------------GLVYRD-LKPENVLVCDPA-CR-------------- 136
SGK496          SQ------------GLVHRD-IKLKNVLLDKQ---N-------------- 138
NIK             SR------------RILHGD-VKADNVLLSSDG--S-------------- 129
SGK424          -------------------------------------------------- 0
SURTK106        EK------------HLFHGD-VAARNILMQSD---L-------------- 150
IKKE            EN------------GIVHRD-IKPGNIMRLVG-EEGQS------------ 143
TBK1            EN------------GIVHRD-IKPGNIMRVIG-EDGQS------------ 143
MOS             SQ------------SIVHLD-LKPANIL--IS-EQ--D------------ 154
LKB1            SQ------------GIVHKD-IKPGNLL--LT-TG--G------------ 140
CAMKK1          CQ------------KIVHRD-IKPSNLL--LG-DD--G------------ 168
CAMKK2          YQ------------KIIHRD-IKPSNLL--VG-ED--G------------ 160
PASK            LK------------DIIHRD-IKDENIV--IA-ED--F------------ 142
PIM1            NC------------GVLHRD-IKDENIL--IDLNR--G------------ 143
PIM3            SC------------GVVHRD-IKDENLL--VDLRS--G------------ 144
PIM2            SR------------GVVHRD-IKDENIL--IDLRR--G------------ 145
COT             SK------------KVIHHD-IKPSNIV--FM-ST--K------------ 130
SCYL2           SS-----------VKMVHGN-ITPENII--LN-KS--G------------ 159
FUSED           -S-----------HRILHRD-MKPQNILLAKGG----------------- 134
ULK1            -S-----------KGIIHRD-LKPQNILLSNPA-GRRANPNSI------- 144
ULK2            -S-----------KGIIHRD-LKPQNILLSYAN-RRKSSVSGI------- 144
ULK3            -E-----------RNISHLD-LKPQNILLSSLE--------KP------- 138
ULK4            -K-----------LGILFCD-ISPRKILLEGPG----------------- 115
IRE1            -S-----------LNIVHRD-LKPHNILISMPN-AHG----KI------- 135
IRE2            -S-----------LHIVHRD-LKPGNILITGPD-SQG----LG------- 135
RNASEL          LS-----------CGYTHQD-LQPQNILIDSKK----------------- 129
MPSK1           -A-----------KGYAHRD-LKPTNILLGDEG----------------- 141
PINK1           -Q-----------QGIAHRD-LKSDNILVEL-D-PDG----CP------- 223
ALK             EN------------HFIHRD-IAARNCLLTCPG---PGR----------- 149
LTK             EN------------HFIHRD-IAARNCLLSCAG---PSR----------- 149
ROS             RM------------HFIHRD-LAARNCLVSVKD-YTSPR----------- 152
IGF1R           AN------------KFVHRD-LAARNCMVA------EDF----------- 149
1IR3A           AK------------KFVHRD-LAARNCMVA------HDF----------- 149
INSR            AK------------KFVHRD-LAARNCMVA------HDF----------- 149
IRR             AN------------KFVHRD-LAARNCMVS------QDF----------- 149
1M14A           DR------------RLVHRD-LAARNVLVK------TPQ----------- 138
EGFR            DR------------RLVHRD-LAARNVLVK------TPQ----------- 138
HER2/ERBB2      DV------------RLVHRD-LAARNVLVK------SPN----------- 138
HER4/ERBB4      ER------------RLVHRD-LAARNVLVK------SPN----------- 138
HER3/ERBB3      EH------------GMVHRN-LAARNVLLK------SPS----------- 138
ITK             EA------------CVIHRD-LAARNCLVG------ENQ----------- 132
TEC             RN------------SFIHRD-LAARNCLVS------EAG----------- 132
TXK             RN------------GYIHRD-LAARNCLVS------STC----------- 132
BMX             SH------------QFIHRD-LAARNCLVD------RDL----------- 132
1K2PA           SK------------QFLHRD-LAARNCLVN------DQG----------- 132
BTK             SK------------QFLHRD-LAARNCLVN------DQG----------- 132
CCK4            NN------------RFVHKD-LAARNCLVS------AQR----------- 147
ROR1            SH------------FFVHKD-LAARNILIG------EQL----------- 155
ROR2            SH------------HVVHKD-LATRNVLVY------DKL----------- 155
MUSK            ER------------KFVHRD-LATRNCLVG------ENM----------- 163
TRKA            GL------------HFVHRD-LATRNCLVG------QGL----------- 153
TRKB            SQ------------HFVHRD-LATRNCLVG------ENL----------- 151
TRKC            SQ------------HFVHRD-LATRNCLVG------ANL----------- 154
DDR1            TL------------NFVHRD-LATRNCLVG------ENF----------- 169
DDR2            SL------------NFVHRD-LATRNCLVG------KNY----------- 160
RYK             RR------------EVIHKD-LAARNCVID------DTL----------- 148
JAK1            SR------------QYVHRD-LAARNVLVESEH----------------- 140
JAK2            TK------------RYIHRD-LATRNILVENEN----------------- 140
JAK3            SR------------RCVHRD-LAARNILVESEA----------------- 140
ACK             SK------------RFIHRD-LAARNLLLATRD----------------- 139
TYK2            AH------------DYIHRD-LAARNVLLDNDR----------------- 139
TNK1            AR------------GLVHRD-LATRNLQLASPR----------------- 142
EPHA1           NH------------NYVHRD-LAARNILVNQNL----------------- 138
EPHA10          EM------------GYVHRG-LAARHVLVSSDL----------------- 138
FAK             SK------------RFVHRD-IAARNVLVSSND----------------- 137
EPHB6           SF------------AFVHRS-LSAHSVLVNSHL----------------- 138
EPHA2           NM------------NYVHRD-LAARNILVNSNL----------------- 139
EPHA8           DL------------GYVHRD-LAARNVLVDSNL----------------- 138
EPHA6           DM------------GYVHRD-LAARNILVNSNL----------------- 180
EPHB1           EM------------NYVHRD-LAARNILVNSNL----------------- 138
EPHB2           DM------------NYVHRD-LAARNILVNSNL----------------- 138
EPHB3           EM------------NYVHRD-LAARNILVNSNL----------------- 138
EPHB4           EM------------SYVHRD-LAARNILVNSNL----------------- 138
EPHA7           DM------------GYVHRD-LAARNILVNSNL----------------- 138
EPHA4           DM------------SYVHRD-LAARNILVNSNL----------------- 138
EPHA3           DM------------GYVHRD-LAARNILINSNL----------------- 138
EPHA5           DM------------GYVHRD-LAARNILINSNL----------------- 138
PYK2            SI------------NCVHRD-IAVRNILVASPE----------------- 137
CSK             GN------------NFVHRD-LAARNVLVSEDN----------------- 132
CTK             SK------------KLVHRD-LAARNILVSEDL----------------- 130
1IEPA           KK------------NFIHRD-LAARNCLVGENH----------------- 134
ABL             KK------------NFIHRD-LAARNCLVGENH----------------- 134
ARG             KK------------NFIHRD-LAARNCLVGENH----------------- 134
BRK             SQ------------NYIHRD-LAARNILVGENT----------------- 134
SRM             EQ------------RVVHRD-LAARNVLVDDGL----------------- 133
FRK             SR------------NYIHRD-LAARNVLVGEHN----------------- 133
FGR             RM------------NYIHRD-LRAANILVGERL----------------- 132
FYN             RM------------NYIHRD-LRSANILVGNGL----------------- 132
SRC             RM------------NYVHRD-LRAANILVGENL----------------- 132
YES             RM------------NYIHRD-LRAANILVGENL----------------- 132
HCK             QR------------NYIHRD-LRAANILVSASL----------------- 132
LYN             RK------------NYIHRD-LRAANVLVSESL----------------- 133
3LCK            ER------------NYIHRD-LRAANILVSDTL----------------- 132
LCK             ER------------NYIHRD-LRAANILVSDTL----------------- 132
BLK             RM------------NSIHRD-LRAANILVSEAL----------------- 132
FER             SK------------NCIHRD-LAARNCLVGENN----------------- 134
FES             SK------------CCIHRD-LAARNCLVTEKN----------------- 135
SYK             ES------------NFVHRD-LAARNVLLVTQH----------------- 136
ZAP70           EK------------NFVHRD-LAARNVLLVNRH----------------- 136
FGFR1           SK------------KCIHRD-LAARNVLVTEDN----------------- 158
FGFR2           SQ------------KCIHRD-LAARNVLVTENN----------------- 158
FGFR3           SQ------------KCIHRD-LAARNVLVTEDN----------------- 158
FGFR4           SR------------KCIHRD-LAARNVLVTEDN----------------- 158
RET             EM------------KLVHRD-LAARNILVAEGR----------------- 163
TIE1            EK------------QFIHRD-LAARNVLVGENL----------------- 153
1FVRA           QK------------QFIHRD-LAARNILVGENY----------------- 153
TIE2            QK------------QFIHRD-LAARNILVGENY----------------- 153
FLT1            SR------------KCIHRD-LAARNILLSENN----------------- 208
KDR             SR------------KCIHRD-LAARNILLSEKN----------------- 207
KDR_AVE         SR------------KCIHRD-LAARNILLSEKN----------------- 150
FLT4            SR------------KCIHRD-LAARNILLSESD----------------- 205
FMS             SK------------NCIHRD-VAARNVLLTNGH----------------- 209
FLT3            FK------------SCVHRD-LAARNVLVTHGK----------------- 214
KIT             SK------------NCIHRD-LAARNILLTHGR----------------- 216
PDGFRA          SK------------NCVHRD-LAARNVLLAQGK----------------- 238
PDGFRB          SK------------NCVHRD-LAARNVLICEGK----------------- 239
MER             NR------------NFLHRD-LAARNCMLRDDM----------------- 149
AXL             TK------------RFIHRD-LAARNCMLNENM----------------- 149
TYRO3           SR------------NFIHRD-LAARNCMLAEDM----------------- 150
MET             SK------------KFVHRD-LAARNCMLDEKF----------------- 139
RON             EQ------------KFVHRD-LAARNCMLDESF----------------- 139
HH498           NLTQ----------PIIHRD-LNSHNILLYED---------G-------- 138
LZK             LHK------------IIHRD-LKSPNVLVTHT---------D-------- 124
DLK             LHK------------IIHRD-LKSPNMLITYD---------D-------- 124
MLK1            DEAI---------VPIIHRD-LKSSNILILQKV-ENGDLSNK-------- 145
MLK3            CEAL---------VPVIHRD-LKSNNILLLQPI-ESDDMEHK-------- 145
MLK2            NDAP---------VPIIHRD-LKSINILILEAI-ENHNLADT-------- 145
MLK4            EEAF---------VPILHRD-LKSSNILLLEKI-EHDDICNK-------- 160
ZAK             MEAP---------VKVIHRD-LKSRNVVIAAD---------G-------- 130
TAK1            SMQP---------KALIHRD-LKPPNLLLVAG--------GT-------- 134
KSR1            AKG------------IVHKD-LKSKNVFYDNG------------------ 132
KSR2            AKG------------ILHKD-LKSKNVFYDNG------------------ 132
ARAF            AKN------------IIHRD-LKSNNIFLHEG---------L-------- 132
RAF1            AKN------------IIHRD-MKSNNIFLHEG---------L-------- 132
BRAF            AKS------------IIHRD-LKSNNIFLHED---------L-------- 132
LRRK2           SAM------------IIYRD-LKPHNVLLFTLY-PNA---AI-------- 133
ANKRD3          CMAP----------PLLHLD-LKPANILLDAH---------Y-------- 134
SGK288          SIKP----------PLLHLD-LKPGNILLDSN---------M-------- 133
RIPK2           NMTP----------PLLHHD-LKTQNILLDNE---------F-------- 141
RIPK3           DQNP----------VLLHRD-LKPSNVLPDPE---------L-------- 134
MLKL            HSEA----------PELHGK-IRSSNFLVTQG---------Y-------- 136
ANPA            NGAI-----------CSHGN-LKSSNCVVDGR---------F-------- 138
ANPB            NSII-----------SSHGS-LKSSNCVVDSR---------F-------- 138
CYGD            HRG------------VAHGR-LKSRNCIVDGR---------F-------- 146
CYGF            HRE------------FVHGR-LKSRNCVVDGR---------F-------- 151
TBCK            KH------------GIVHRA-LSPHNILLDRKG----------------- 111
ERK1            SA------------NVLHRD-LKPSNLLSNT-----TC------------ 137
3ERK            SA------------NVLHRD-LKPSNLLLNT-----TC------------ 137
ERK2            SA------------NVLHRD-LKPSNLLLNT-----TC------------ 137
ERK5            SA------------QVIHRD-LKPSNLLVNE-----NC------------ 140
1JNK            SA------------GIIHRD-LKPSNIVVKS-----DC------------ 138
1PMNA           SA------------GIIHRD-LKPSNIVVKS-----DC------------ 138
JNK3            SA------------GIIHRD-LKPSNIVVKS-----DC------------ 138
JNK1            SA------------GIIHRD-LKPSNIVVKS-----DC------------ 138
JNK2            SA------------GIIHRD-LKPSNIVVKS-----DC------------ 138
1P38            SA------------DIIHRD-LKPSNLAVNE-----DC------------ 139
P38A            SA------------DIIHRD-LKPSNLAVNE-----DC------------ 139
P38B            SA------------GIIHRD-LKPSNVAVNE-----DC------------ 147
P38D            SA------------GVVHRD-LKPGNLAVNE-----DC------------ 138
P38G            AA------------GIIHRD-LKPGNLAVNE-----DC------------ 139
NLK             SA------------GILHRD-IKPGNLLVNS-----NC------------ 139
ERK7            SG------------HVVHRD-QKPSNVLLDA-----NC------------ 156
ERK3            SA------------NVLHRD-LKPANLFINT----EDL------------ 146
ERK4            SA------------NVLHRD-LKPANIFIST----EDL------------ 143
ICK             KH------------GFFHRD-LKPENLLCMG-----PE------------ 134
MAK             KH------------GFFHRD-MKPENLLCMG-----PE------------ 134
PCTAIRE1        RQ------------KVLHRD-LKPQNLLINE-----RG------------ 134
PCTAIRE2        RR------------KVLHRD-LKPQNLLINE-----KG------------ 134
PCTAIRE3        HR------------KILHRD-LKPQNLLINE-----RG------------ 134
PFTAIRE1        QR------------YILHRD-LKPQNLLISD-----TG------------ 134
PFTAIRE2        HQ------------HVLHRD-LKPQNLLISH-----LG------------ 134
CDC2            SR------------RVLHRD-LKPQNLLIDD-----KG------------ 137
1HCL            SH------------RVLHRD-LKPQNLLINT-----EG------------ 132
CDK2            SH------------RVLHRD-LKPQNLLINT-----EG------------ 136
CDK3            SH------------RVIHRD-LKPQNLLINE-----LG------------ 136
CDK5            SR------------NVLHRD-LKPQNLLINR-----NG------------ 135
CDK7            QH------------WILHRD-LKPNNLLLDE-----NG------------ 138
CDK4            AN------------CIVHRD-LKPENILVTS-----GG------------ 147
1BLXA           SH------------RVVHRD-LKPQNILVTS-----SG------------ 145
CDK6            SH------------RVVHRD-LKPQNILVTS-----SG------------ 145
PITSLRE         DN------------WILHRD-LKTSNLLLSH-----AG------------ 137
CDK10           RN------------FIIHRD-LKVSNLLMTD-----KG------------ 137
CDK9            RN------------KILHRD-MKAANVLITR-----DG------------ 143
CHED            KK------------NFLHRD-IKCSNILLNN-----RG------------ 145
CRK7            KK------------NFLHRD-IKCSNILLNN-----SG------------ 145
CCRK            AN------------NIVHRD-LKPANLLISA-----SG------------ 136
CDK11           AN------------WVLHRD-LKPANILVMGEG-PERG------------ 148
CDK8            AN------------WVLHRD-LKPANILVMGEG-PERG------------ 148
IKKA            EN------------KIIHRD-LKPENIVLQDVG-G--------------- 143
IKKB            EN------------RIIHRD-LKPENIVLQQGE-Q--------------- 144
1PHK            KL------------NIVHRD-LKPENILLDDD------------------ 142
PHKG1           KL------------NIVHRD-LKPENILLDDN------------------ 142
PHKG2           AN------------NIVHRD-LKPENILLDDN------------------ 141
CAMK2A          QM------------GVVHRD-LKPENLLLASKL-K--------------- 136
CAMK2B          QM------------GVVHRD-LKPENLLLASKC-K--------------- 136
CAMK2G          QH------------DIVHRD-LKPENLLLASKC-K--------------- 136
CAMK2D          LN------------GIVHRD-LKPENLLLASKS-K--------------- 136
CASK            DN------------NIIHRD-VKPHCVLLASKE-N--------------- 143
1IA8A           GI------------GITHRD-IKPENLLLDERD-N--------------- 132
CHK1            GI------------GITHRD-IKPENLLLDERD-N--------------- 135
CLK1            SN------------KLTHTD-LKPENILFVQSD-YTEAYNPKIKRDERTL 156
CLK4            HN------------KLTHTD-LKPENILFVKSD-YVVKYNSKMKRDERTL 155
CLK2            DN------------KLTHTD-LKPENILFVNSD-YELTYNLEKKRDERSV 156
CLK3            EN------------QLTHTD-LKPENILFVNSE-FETLYNEHKSCEEKSV 156
MAP2K5          S------------LKILHRD-VKPSNMLVNTRG----------------- 130
MAP2K3          SK-----------LSVIHRD-VKPSNVLINKEG----------------- 139
MAP2K6          SK-----------LSVIHRD-VKPSNVLINALG----------------- 139
MAP2K4          EN-----------LKIIHRD-IKPSNILLDRSG----------------- 140
MAP2K7          EK-----------HGVIHRD-VKPSNILLDERG----------------- 136
MAP2K1          EK-----------HKIMHRD-VKPSNILVNSRG----------------- 135
MAP2K2          EK-----------HQIMHRD-VKPSNILVNSRG----------------- 135
CDKL5           KN------------DIVHRD-IKPENLLISHN-D---------------- 135
CDKL1           KH------------NCIHRD-VKPENILITKH-S---------------- 135
CDKL4           IH------------NCIHRD-IKPENILITKQ-G---------------- 135
CDKL2           SH------------NIIHRD-IKPENILVSQS-G---------------- 135
CDKL3           SN------------NIIHRD-IKPENILVSQS-G---------------- 134
1I09B           SF------------GICHRD-IKPQNLLLDPDTA---------------- 139
GSK3B           SF------------GICHRD-IKPQNLLLDPDTA---------------- 139
1J1BA           SF------------GICHRD-IKPQNLLLDPDTA---------------- 139
GSK3A           SQ------------GVCHRD-IKPQNLLVDPDTA---------------- 139
LATS1           KM------------GFIHRD-IKPDNILIDRDG----------------- 136
LATS2           KM------------GFIHRD-IKPDNILIDLDG----------------- 136
NDR1            QL------------GFIHRD-IKPDNLLLDSKG----------------- 136
NDR2            QL------------GFIHRD-IKPDNLLLDAKG----------------- 136
MAST1           NY------------GIVHRD-LKPDNLLITSMG----------------- 136
MAST4           NY------------GIVHRD-LKPDNLLVTSMG----------------- 136
MAST2           NY------------GIVHRD-LKPDNLLITSMG----------------- 136
MAST3           NY------------GIVHRD-LKPDNLLITSLG----------------- 136
MRCKA           QL------------HYVHRD-IKPDNILMDMNG----------------- 137
MRCKB           QL------------HYVHRD-IKPDNVLLDVNG----------------- 137
DMPK2           QL------------GYVHRD-VKPDNVLLDVNG----------------- 137
DMPK1           RL------------GYVHRD-IKPDNILLDRCG----------------- 137
ROCK1           SM------------GFIHRD-VKPDNMLLDKSG----------------- 135
ROCK2           SM------------GLIHRD-VKPDNMLLDKHG----------------- 135
CRIK            LM------------GYVHRD-IKPENILVDRTG----------------- 137
MASTL           RH------------GIIHRD-LKPDNMLISNEG----------------- 134
1O6LA           S------------RDVVYRD-IKLENLMLDKDG----------------- 136
AKT2            S------------RDVVYRD-IKLENLMLDKDG----------------- 136
AKT1            SE-----------KNVVYRD-LKLENLMLDKDG----------------- 137
AKT3            S------------GKIVYRD-LKLENLMLDKDG----------------- 136
MSK1            K------------LGIIYRD-IKLENILLDSNG----------------- 141
MSK2            K------------LGIIYRD-LKLENVLLDSEG----------------- 141
P70S6K          Q------------KGIIYRD-LKPENIMLNHQG----------------- 140
P70S6KB         S------------QGIIYRD-LKPENIMLSSQG----------------- 140
RSK1            S------------LGIIYRD-LKPENILLDEEG----------------- 138
RSK3            S------------LGIIYRD-LKPENILLDEEG----------------- 138
RSK2            S------------LGIIYRD-LKPENILLDEEG----------------- 138
RSK4            Q------------LGIVYRD-LKPENILLDEIG----------------- 138
1FOTA           S------------KDIIYRD-LKPENILLDKNG----------------- 136
1CDKA           S------------LDLIYRD-LKPENLLIDQQG----------------- 136
PKACA           S------------LDLIYRD-LKPENLLIDQQG----------------- 136
PKACB           S------------LDLIYRD-LKPENLLIDHQG----------------- 136
PKACG           S------------LDLIHRD-LKPENLLIDQQG----------------- 136
PRKX            S------------KEIVYRD-LKPENILLDRDG----------------- 136
PRKY            S------------KEIVYRD-LKPENILLDRDG----------------- 136
PKCA            K------------RGIIYRD-LKLDNVMLDSEG----------------- 137
PKCB            S------------KGIIYRD-LKLDNVMLDSEG----------------- 137
PKCG            N------------QGIIYRD-LKLDNVMLDAEG----------------- 142
PKCE            Q------------HGVIYRD-LKLDNILLDAEG----------------- 137
PKCH            D------------KGIIYRD-LKLDNVLLDHEG----------------- 137
PKCD            S------------KGIIYRD-LKLDNVLLDRDG----------------- 137
PKCT            S------------KGIVYRD-LKLDNILLDKDG----------------- 137
PKCI            E------------RGIIYRD-LKLDNVLLDSEG----------------- 137
PKCZ            E------------RGIIYRD-LKLDNVLLDADG----------------- 137
PKN1            E------------HKIVYRD-LKLDNLLLDTEG----------------- 138
PKN2            E------------HKIVYRD-LKLDNLLLDTEG----------------- 138
PKN3            E------------KKIIYRD-LKLDNLLLDAQG----------------- 138
SGK             S------------LNIVYRD-LKPENILLDSQG----------------- 137
SGK2            S------------LNIIYRD-LKPENILLDCQG----------------- 137
SGK3            S------------IKIVYRD-LKPENILLDSVG----------------- 137
PKG1            S------------KGIIYRD-LKPENLILDHRG----------------- 137
PKG2            R------------LGIIYRD-LKPENLILDAEG----------------- 136
AURB            GK------------KVIHRD-IKPENLLLGLKG----------------- 136
AURC            DK------------KVIHRD-IKPENLLLGFRG----------------- 136
AURA            SK------------RVIHRD-IKPENLLLGSAG----------------- 136
AURORA2_AVE     SK------------RVIHRD-IKPENLLLGSAG----------------- 136
PLK1            RN------------RVIHRD-LKLGNLFLNEDL----------------- 136
PLK2            EQ------------EILHRD-LKLGNFFINEAM----------------- 136
PLK3            QR------------GILHRD-LKLGNFFITENM----------------- 136
PLK4            SH------------GILHRD-LTLSNLLLTRNM----------------- 137
NEK11           ER------------RILHRD-LKSKNVFLKNNL----------------- 142
YANK1           NQ------------RIIHRD-MKPDNILLDEHG----------------- 136
YANK2           RY------------HIIHRD-IKPDNILLDEHG----------------- 136
YANK3           GQ------------HIIHRD-VKPDNILLDERG----------------- 136
SGK494          DL------------GIMHRD-VKMENILLDERG----------------- 135
DOMAIN2_MSK1    DV------------GVVHRD-LKPENLLFTDEN-DN-L------------ 134
DOMAIN2_MSK2    EE-----------AGVVHRD-LKPENILYADDT-P-GA------------ 129
DOMAIN2_RSK1    SQ------------GVVHRD-LKPSNILYRDES-GSPE------------ 134
DOMAIN2_RSK2    AQ------------GVVHRD-LKPSNILYVDES-GNPE------------ 134
DOMAIN2_RSK3    SQ------------GVVHRD-LKPSNILYVDES-GNPE------------ 134
DOMAIN2_RSK4    CQ------------GVVHRD-LKPSNILYMDES-ASAD------------ 134
DRAK1           TR------------DVVHLD-LKPQNILLTSES-P-LG------------ 141
DRAK2           QN------------NIVHLD-LKPQNILLSSIY-P-LG------------ 141
1JKSA           SL------------QIAHFD-LKPENIMLLDRN-VPKP------------ 143
DAPK1           SL------------QIAHFD-LKPENIMLLDRN-VPKP------------ 143
DAPK3           SK------------RIAHFD-LKPENIMLLDKN-VPNP------------ 143
DAPK2           TK------------KIAHFD-LKPENIMLLDKN-IPIP------------ 143
SGK085          QM------------YILHLD-LKPENILCVNRD-A--K------------ 136
CAMLCK          QH------------YILHLD-LKPENILCVNQT-G--H------------ 136
SKMLCK          KM------------RVLHLD-LKPENILCVNTT-G--H------------ 136
SMMLCK          KQ------------GIVHLD-LKPENIMCVNKT-G--T------------ 136
1KOBA           EH------------SIVHLD-IKPENIMCETKK-A--S------------ 136
1TKIA           SH------------NIGHFD-IRPENIIYQTRR-S--S------------ 135
TTN             SH------------NIGHFD-IRPENIIYQTRR-S--S------------ 135
PKD1            FK------------NIVHCD-LKPENVLLASAD-P-FP------------ 139
PKD3            FK------------NIVHCD-LKPENVLLASAE-P-FP------------ 139
PKD2            FK------------NIVHCD-LKPENVLLASAD-P-FP------------ 139
PSKH1           AL------------GITHRD-LKPENLLYYHPG-T-DS------------ 136
PSKH2           AL------------QITHRN-LKPENLLYYHPG-E-ES------------ 136
CAMK1A          DL------------GIVHRD-LKPENLLYYSLD-E-DS------------ 137
CAMK1D          RM------------GIVHRD-LKPENLLYYSQD-E-ES------------ 137
CAMK1B          SL------------GIVHRD-LKPENLLYATPF-E-DS------------ 137
CAMK1G          EN------------GIVHRD-LKPENLLYLTPE-E-NS------------ 136
CAMK4           EN------------GIVHRD-LKPENLLYATPA-P-DA------------ 134
DCAMKL1         SL------------NIVHRD-IKPENLLVYEHQ-DGSK------------ 138
DCAMKL2         GL------------SIVHRD-IKPENLLVCEYP-DGTK------------ 138
DCAMKL3         DK------------SIVHRD-LKPENLLVQRNE-DKST------------ 138
CHK2            EN------------GIIHRD-LKPENVLLSSQE-E-DC------------ 143
MAPKAPK2        SI------------NIAHRD-VKPENLLYTSKR-P-NA------------ 138
MAPKAPK3        SH------------NIAHRD-VKPENLLYTSKE-K-DA------------ 138
MAPKAPK5        LL------------NIAHRD-LKPENLLFKDNS-L-DA------------ 142
MNK1            TK------------GIAHRD-LKPENILCESPE-K-VS------------ 138
MNK2            NK------------GIAHRD-LKPENILCEHPN-Q-VS------------ 137
VACAMKL         SL------------KIVHRN-LKLENLVYYNRL-K-NS------------ 137
GCK             SQ------------GKIHRD-IKGANLLLTL-Q-GD-------------- 134
KHS1            TK------------GKMHRD-IKGANILLTD-H-GD-------------- 134
KHS2            SK------------GKMHRD-IKGANILLTD-N-GH-------------- 134
HPK1            SQ------------KKIHRD-IKGANILIND-A-GE-------------- 134
MST1            FM------------RKIHRD-IKAGNILLNT-E-GH-------------- 133
MST2            FM------------RKIHRD-IKAGNILLNT-E-GH-------------- 133
MST3            SE------------KKIHRD-IKAANVLLSE-H-GE-------------- 134
YSK1            SE------------RKIHRD-IKAANVLLSE-Q-GD-------------- 134
MST4            SE------------KKIHRD-IKAANVLLSE-Q-GD-------------- 134
LOK             SK------------RIIHRD-LKAGNVLMTL-E-GD-------------- 135
SLK             DN------------KIIHRD-LKAGNILFTL-D-GD-------------- 135
MAP3K4          EH------------GIVHRD-IKGANIFLTS-S-GL-------------- 134
MAP3K2          SN------------MILHRD-IKGANILRDS-T-GN-------------- 141
MAP3K3          SN------------MIVHRD-IKGANILRDS-A-GN-------------- 141
MAP3K8          EN------------CVVHRD-IKGNNVMLMP-T-GI-------------- 139
MAP3K5          DN------------QIVHRD-IKGDNVLINTYS-GV-------------- 143
MAP3K7          EN------------QIVHRD-IKGDNVLVNTYS-GV-------------- 134
MAP3K6          DN------------HIVHRD-IKGDNVLINTFS-GL-------------- 133
PAK1            SN------------QVIHRD-IKSDNILLGM-D-GS-------------- 133
PAK3            SN------------QVIHRD-IKSDNILLGM-D-GS-------------- 133
PAK2            AN------------QVIHRD-IKSDNVLLGM-E-GS-------------- 134
PAK4            AQ------------GVIHRD-IKSDSILLTH-D-GR-------------- 133
PAK5            NQ------------GVIHRD-IKSDSILLTS-D-GR-------------- 133
PAK6            AQ------------GVIHRD-IKSDSILLTL-D-GR-------------- 133
OSR1            KN------------GQIHRD-VKAGNILLGE-D-GS-------------- 143
STLK3           RN------------GQIHRD-LKAGNILLGE-D-GS-------------- 143
TAO1            SH------------TMIHRD-IKAGNILLTE-P-GQ-------------- 137
TAO3            SH------------ALIHRD-IKAGNILLTE-P-GQ-------------- 137
TAO2            SH------------NMIHRD-VKAGNILLSE-P-GL-------------- 137
MYO3A           NN------------KTIHRD-VKGNNILLTT-E-GG-------------- 143
MYO3B           NN------------RIIHRD-VKGNNILLTT-E-GG-------------- 143
ZC1/HGK         IH------------HVIHRD-IKGQNVLLTE-N-AE-------------- 142
ZC3/MINK        AH------------KVIHRD-IKGQNVLLTE-N-AE-------------- 142
ZC2/TNIK        QH------------KVIHRD-IKGQNVLLTE-N-AE-------------- 142
ZC4/NRK         AH------------RVIHRD-IKGQNVLLTH-N-AE-------------- 166
MAP3K1          EN------------QIIHRD-VKGANLLIDS-T-GQ-------------- 140
GAK             RQK----------PPIIHRD-LKVENLLLSNQ--GT-------------- 147
SGK495          QKN------------IVHRD-LKLGNMVLNKRT--H-------------- 53
TRB1            QSA------------IVLGD-LKLRKFVFSTEE-RT-------------- 121
TRB2            DGG------------LVLRD-LKLRKFIFKDEE-RT-------------- 126
TRB3            QHG------------LVLRD-LKLCRFVFADRE-RK-------------- 124
SSTK            DHH------------LVHRD-LKCENVLLSPDE-RR-------------- 138
TSSK3           GCG------------VAHRD-LKCENALLQG---FN-------------- 137
TSSK1           DLD------------VVHRD-LKCDNLLLDKD--FN-------------- 138
TSSK2           DLD------------IVHRD-LKCENLLLDKD--FN-------------- 138
TSSK4           SKS------------IVHRD-LKLENLLLDKW--EN-------------- 137
HUNK            RAG------------VVHRD-LKIENLLLDED--NN-------------- 139
SNRK            KLH------------VVHRD-LKPENVVFFEKQ-GL-------------- 138
NIM1            ENQ------------IIHRD-LKAENVFYTSN--TC-------------- 136
MELK            SQG------------YAHRD-LKPENLLFDEY--HK-------------- 135
BRSK1           SYS------------ICHRD-LKPENLLLDEK--NN-------------- 136
BRSK2           SHS------------ICHRD-LKPENLLLDEK--NN-------------- 136
MARK1           QKY------------IVHRD-LKAENLLLDGD--MN-------------- 136
MARK2           QKF------------IVHRD-LKAENLLLDAD--MN-------------- 136
MARK3           QKR------------IVHRD-LKAENLLLDAD--MN-------------- 136
MARK4           QKN------------IVHRD-LQAENLLLDAE--AN-------------- 136
QIK             GRK------------IVHRD-LKAENLLLDNN--MN-------------- 136
SIK             DHH------------IVHRD-LKTENLLLDGN--MD-------------- 136
QSK             CRN------------IVHRD-LKAENLLLDAN--LN-------------- 136
AMPKA1          RHM------------VVHRD-LKPENVLLDAH--MN-------------- 137
AMPKA2          RHM------------VVHRD-LKPENVLLDAH--MN-------------- 137
NUAK1           KNG------------VVHRD-LKLENILLDDN--CN-------------- 137
NUAK2           QNR------------VVHRD-LKLENILLDAN--GN-------------- 136
BIKE            QCK----------TPIIHRD-LKVENILLNDG--GN-------------- 143
AAK1            QCK----------TPIIHRD-LKVENILLHDR--GH-------------- 144
LIMK1           SMN------------IIHRD-LNSHNCLVRE-N-K---N----------- 135
LIMK2           SMC------------IIHRD-LNSHNCLIKL-D-K---T----------- 134
TESK1           SKG------------VFHRD-LTSKNCLVRR-E-DRGFT----------- 135
TESK2           FKG------------IFHRD-LTSKNCLIKR-D-ENGYS----------- 115
WNK1            TRTP----------PIIHRD-LKCDNIFITGPT-G---S----------- 143
WNK3            TRTP----------PIIHRD-LKCDNIFITGPT-G---S----------- 143
WNK2            TRTP----------PIIHRD-LKCDNIFITGPT-G---S----------- 143
WNK4            SRVP----------PILHRD-LKCDNVFITGPT-G---S----------- 143
NEK10           KE-K----------RIVHRD-QTPNNIMLGD-K-D---K----------- 150
NEK6            SRR------------VMHRD-IKPANVFITA-T-G---V----------- 141
NEK7            SRR------------VMHRD-IKPANVFITA-T-G---V----------- 141
NEK2            RRSD-------GGHTVLHRD-LKPANVFLDG-K-Q---N----------- 147
NEK1            DRK------------ILHRD-IKSQNIFLTK-D-G---T----------- 138
NEK5            DRK------------ILHRD-IKAQNIFLSK-N-G---M----------- 138
NEK3            KKR------------VLHRD-IKSKNIFLTQ-N-G---K----------- 137
NEK4            EKH------------ILHRD-LKTQNVFLTR-T-N---I----------- 139
NEK8            THL------------ILHRD-LKTQNILLDK-H-R--MV----------- 139
NEK9            KAG------------ILHRD-IKTLNIFLTK-A-N---L----------- 138
NRBP1           SCDP----------PIIHGN-LTCDTIFIQH-N-G---L----------- 151
NRBP2           ACSP----------PIIHGN-LTSDTIFIQH-N-G---L----------- 151
CLIK1           KN------------HIVHRD-LKPDNILITER-------SGTP------- 174
CLIK1L          KN------------QIIHRD-LKPDNILISQTR-LD-TSDLEP------- 177
STK33           NN------------DIVHRD-LKLENIMVKSSL-IDDNNEINL------- 144
DOMAIN2_GCN2    SN------------SVVHKV-LSASNVLVDAEG-T--------------- 159
SCYL1           ND-----------CSLIHNN-VCMAAVFVDRAG-E--------------- 126
SCYL3           DR-----------GHLTHNN-VCLSSVFVSEDG-H--------------- 113
DOMAIN2_JAK1    DK------------DLVHGN-VCTKNLLLAREG-ID-------------- 146
DOMAIN2_TYK2    NK------------NLVHGN-VCGRNILLARLG-LA-------------- 160
DOMAIN2_JAK2    EN------------TLIHGN-VCAKNILLIREE-DRK------------- 144
DOMAIN2_JAK3    DK------------GLPHGN-VSARKVLLAREG-A--------------- 140
ILK             TL-----------EPLIPRHALNSRSVMIDEDM-T--------------- 140
LRRK1           KK------------NIIFCD-LKSDNILVWSLD-VK-------------- 159
PBK             QE-----------KKLLHGD-IKSSNVVIKGDF----------------- 148
WEE1            SM------------SLVHMD-IKPSNIFISRTS-IP-------------- 142
WEE1B           NS------------SMVHLD-IKPSNIFICHKM-QSESS----------- 145
SGK071          HL------------DIIHRN-LKPSNIILISSD-H--------------- 143
PIK3R4          KS------------GVRHGD-IKTENVMVTSWN-W--------------- 136
MSSK1           TKC-----------KIIHTD-IKPENILLCVGD-AYIRRLAAEATEWQQA 162
SRPK1           TKC-----------RIIHTD-IKPENILLSVNE-QYIRRLAAEATEWQRS 162
SRPK2           SKC-----------KIIHTD-IKPENILMCVDD-AYVRRMAAEATEWQKA 162
RSKL1           RE------------GIVCRD-LNPNNILLNDRG-H--------------- 121
RSKL2           EQ------------GVLCRD-LHPGNLLLDQAG-H--------------- 273
SGK396          KA------------DIIHGS-LHQNNVFALNRE-Q--------------- 135
VRK1            EH------------EYVHGD-IKASNLLLNYKN-PD-------------- 155
VRK2            EN------------EYVHGD-VKAANLLLGYKN-PD-------------- 152
VRK3            EN------------EYVHGN-VTAENIFVDPED-QS-------------- 100
BUB1            DC------------EIIHGD-IKPDNFILGNGF-LEQDDE---------- 149
BUBR1           KA------------EIVHGD-LSPRCLILRNRI-HDPYDC---------- 148
SGK196          HS------------PVGTRV-MCDSNDLPKTLS-QY-------------- 135
SGK493          HSP---------LGSVTLLD-FRPRQFVL-VDG-E--------------- 150
                                                                  

DYRK1A          RSA----------------------------------------------- 144
DYRK1B          RSA----------------------------------------------- 144
DYRK2           RSG----------------------------------------------- 142
DYRK3           RSS----------------------------------------------- 142
DYRK4           QAS----------------------------------------------- 142
HIPK1           RQPY---------------------------------------------- 142
HIPK2           RQPY---------------------------------------------- 142
HIPK3           RQPY---------------------------------------------- 142
HIPK4           RCPF---------------------------------------------- 142
PRP4            ---T---------------------------------------------- 142
MOK             -------------------------------------------------- 136
1A6O            ---R---------------------------------------------- 131
1LPUA           ---R---------------------------------------------- 131
CK2A1           ---R---------------------------------------------- 131
CK2A1-RS        ---R---------------------------------------------- 131
CK2A2           ---K---------------------------------------------- 131
HSER            -------------------------------------------------- 138
SLOB            -------------------------------------------------- 157
CDC7            ---K---------------------------------------------- 133
1CSN            KNAN---------------------------------------------- 137
CK1G1           KKEH---------------------------------------------- 138
CK1G3           KTQQ---------------------------------------------- 137
CK1G2           KRQH---------------------------------------------- 137
CK1A            RHCN---------------------------------------------- 135
CK1A2           RHCN---------------------------------------------- 135
1CKJA           KKGN---------------------------------------------- 135
CK1D            KKGN---------------------------------------------- 135
CK1E            KKGN---------------------------------------------- 135
TTBK1           STYR---------------------------------------------- 137
TTBK2           STCR---------------------------------------------- 137
TLK1            -ACG---------------------------------------------- 146
TLK2            -ACG---------------------------------------------- 146
GPRK4           -------------------------------------------------- 138
GPRK6           -------------------------------------------------- 138
GPRK5           -------------------------------------------------- 138
RHOK            -------------------------------------------------- 140
GPRK7           -------------------------------------------------- 138
BARK1           -------------------------------------------------- 139
BARK2           -------------------------------------------------- 139
TTK             -------------------------------------------------- 134
RIPK1           -------------------------------------------------- 134
HASPIN          SCGL---------------------------------------------- 198
GCN2            -------------------------------------------------- 271
HRI             -------------------------------------------------- 289
KIS             -------------------------------------------------- 149
PDK1            -------------------------------------------------- 136
PKR             -------------------------------------------------- 160
PEK             -------------------------------------------------- 357
PRPK            -------------------------------------------------- 145
DOMAIN2_OBSCN   -------------------------------------------------- 132
DOMAIN2_SPEG    -------------------------------------------------- 132
LMR1            -------------------------------------------------- 141
LMR2            -------------------------------------------------- 141
LMR3            -------------------------------------------------- 146
SGK307          -------------------------------------------------- 49
STLK5           -------------------------------------------------- 139
STLK6           -------------------------------------------------- 139
STLK6-RS        -------------------------------------------------- 139
OBSCN           -------------------------------------------------- 134
SPEG            -------------------------------------------------- 135
TRAD            -------------------------------------------------- 135
TRIO            -------------------------------------------------- 135
SGK223          -------------------------------------------------- 140
SGK269          -------------------------------------------------- 141
ALK1            -------------------------------------------------- 141
ALK2            -------------------------------------------------- 141
IRAK4           -------------------------------------------------- 138
BMPR2           -------------------------------------------------- 143
TGFBR2          -------------------------------------------------- 148
ACTR2           -------------------------------------------------- 143
ACTR2B          -------------------------------------------------- 144
1B6CB           -------------------------------------------------- 141
TGFBR1          -------------------------------------------------- 141
ALK4            -------------------------------------------------- 141
ALK7            -------------------------------------------------- 141
BMPR1A          -------------------------------------------------- 141
BMPR1B          -------------------------------------------------- 141
IRAK1           -------------------------------------------------- 141
IRAK2           -------------------------------------------------- 138
IRAK3           -------------------------------------------------- 141
MISR2           -------------------------------------------------- 143
MYT1            -------------------------------------------------- 136
SBK             -------------------------------------------------- 136
SGK110          -------------------------------------------------- 135
SGK069          -------------------------------------------------- 136
SGK496          -------------------------------------------------- 138
NIK             -------------------------------------------------- 129
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 150
IKKE            -------------------------------------------------- 143
TBK1            -------------------------------------------------- 143
MOS             -------------------------------------------------- 154
LKB1            -------------------------------------------------- 140
CAMKK1          -------------------------------------------------- 168
CAMKK2          -------------------------------------------------- 160
PASK            -------------------------------------------------- 142
PIM1            -------------------------------------------------- 143
PIM3            -------------------------------------------------- 144
PIM2            -------------------------------------------------- 145
COT             -------------------------------------------------- 130
SCYL2           -------------------------------------------------- 159
FUSED           -------------------------------------------------- 134
ULK1            -------------------------------------------------- 144
ULK2            -------------------------------------------------- 144
ULK3            -------------------------------------------------- 138
ULK4            -------------------------------------------------- 115
IRE1            -------------------------------------------------- 135
IRE2            -------------------------------------------------- 135
RNASEL          -------------------------------------------------- 129
MPSK1           -------------------------------------------------- 141
PINK1           -------------------------------------------------- 223
ALK             -------------------------------------------------- 149
LTK             -------------------------------------------------- 149
ROS             -------------------------------------------------- 152
IGF1R           -------------------------------------------------- 149
1IR3A           -------------------------------------------------- 149
INSR            -------------------------------------------------- 149
IRR             -------------------------------------------------- 149
1M14A           -------------------------------------------------- 138
EGFR            -------------------------------------------------- 138
HER2/ERBB2      -------------------------------------------------- 138
HER4/ERBB4      -------------------------------------------------- 138
HER3/ERBB3      -------------------------------------------------- 138
ITK             -------------------------------------------------- 132
TEC             -------------------------------------------------- 132
TXK             -------------------------------------------------- 132
BMX             -------------------------------------------------- 132
1K2PA           -------------------------------------------------- 132
BTK             -------------------------------------------------- 132
CCK4            -------------------------------------------------- 147
ROR1            -------------------------------------------------- 155
ROR2            -------------------------------------------------- 155
MUSK            -------------------------------------------------- 163
TRKA            -------------------------------------------------- 153
TRKB            -------------------------------------------------- 151
TRKC            -------------------------------------------------- 154
DDR1            -------------------------------------------------- 169
DDR2            -------------------------------------------------- 160
RYK             -------------------------------------------------- 148
JAK1            -------------------------------------------------- 140
JAK2            -------------------------------------------------- 140
JAK3            -------------------------------------------------- 140
ACK             -------------------------------------------------- 139
TYK2            -------------------------------------------------- 139
TNK1            -------------------------------------------------- 142
EPHA1           -------------------------------------------------- 138
EPHA10          -------------------------------------------------- 138
FAK             -------------------------------------------------- 137
EPHB6           -------------------------------------------------- 138
EPHA2           -------------------------------------------------- 139
EPHA8           -------------------------------------------------- 138
EPHA6           -------------------------------------------------- 180
EPHB1           -------------------------------------------------- 138
EPHB2           -------------------------------------------------- 138
EPHB3           -------------------------------------------------- 138
EPHB4           -------------------------------------------------- 138
EPHA7           -------------------------------------------------- 138
EPHA4           -------------------------------------------------- 138
EPHA3           -------------------------------------------------- 138
EPHA5           -------------------------------------------------- 138
PYK2            -------------------------------------------------- 137
CSK             -------------------------------------------------- 132
CTK             -------------------------------------------------- 130
1IEPA           -------------------------------------------------- 134
ABL             -------------------------------------------------- 134
ARG             -------------------------------------------------- 134
BRK             -------------------------------------------------- 134
SRM             -------------------------------------------------- 133
FRK             -------------------------------------------------- 133
FGR             -------------------------------------------------- 132
FYN             -------------------------------------------------- 132
SRC             -------------------------------------------------- 132
YES             -------------------------------------------------- 132
HCK             -------------------------------------------------- 132
LYN             -------------------------------------------------- 133
3LCK            -------------------------------------------------- 132
LCK             -------------------------------------------------- 132
BLK             -------------------------------------------------- 132
FER             -------------------------------------------------- 134
FES             -------------------------------------------------- 135
SYK             -------------------------------------------------- 136
ZAP70           -------------------------------------------------- 136
FGFR1           -------------------------------------------------- 158
FGFR2           -------------------------------------------------- 158
FGFR3           -------------------------------------------------- 158
FGFR4           -------------------------------------------------- 158
RET             -------------------------------------------------- 163
TIE1            -------------------------------------------------- 153
1FVRA           -------------------------------------------------- 153
TIE2            -------------------------------------------------- 153
FLT1            -------------------------------------------------- 208
KDR             -------------------------------------------------- 207
KDR_AVE         -------------------------------------------------- 150
FLT4            -------------------------------------------------- 205
FMS             -------------------------------------------------- 209
FLT3            -------------------------------------------------- 214
KIT             -------------------------------------------------- 216
PDGFRA          -------------------------------------------------- 238
PDGFRB          -------------------------------------------------- 239
MER             -------------------------------------------------- 149
AXL             -------------------------------------------------- 149
TYRO3           -------------------------------------------------- 150
MET             -------------------------------------------------- 139
RON             -------------------------------------------------- 139
HH498           -------------------------------------------------- 138
LZK             -------------------------------------------------- 124
DLK             -------------------------------------------------- 124
MLK1            -------------------------------------------------- 145
MLK3            -------------------------------------------------- 145
MLK2            -------------------------------------------------- 145
MLK4            -------------------------------------------------- 160
ZAK             -------------------------------------------------- 130
TAK1            -------------------------------------------------- 134
KSR1            -------------------------------------------------- 132
KSR2            -------------------------------------------------- 132
ARAF            -------------------------------------------------- 132
RAF1            -------------------------------------------------- 132
BRAF            -------------------------------------------------- 132
LRRK2           -------------------------------------------------- 133
ANKRD3          -------------------------------------------------- 134
SGK288          -------------------------------------------------- 133
RIPK2           -------------------------------------------------- 141
RIPK3           -------------------------------------------------- 134
MLKL            -------------------------------------------------- 136
ANPA            -------------------------------------------------- 138
ANPB            -------------------------------------------------- 138
CYGD            -------------------------------------------------- 146
CYGF            -------------------------------------------------- 151
TBCK            -------------------------------------------------- 111
ERK1            -------------------------------------------------- 137
3ERK            -------------------------------------------------- 137
ERK2            -------------------------------------------------- 137
ERK5            -------------------------------------------------- 140
1JNK            -------------------------------------------------- 138
1PMNA           -------------------------------------------------- 138
JNK3            -------------------------------------------------- 138
JNK1            -------------------------------------------------- 138
JNK2            -------------------------------------------------- 138
1P38            -------------------------------------------------- 139
P38A            -------------------------------------------------- 139
P38B            -------------------------------------------------- 147
P38D            -------------------------------------------------- 138
P38G            -------------------------------------------------- 139
NLK             -------------------------------------------------- 139
ERK7            -------------------------------------------------- 156
ERK3            -------------------------------------------------- 146
ERK4            -------------------------------------------------- 143
ICK             -------------------------------------------------- 134
MAK             -------------------------------------------------- 134
PCTAIRE1        -------------------------------------------------- 134
PCTAIRE2        -------------------------------------------------- 134
PCTAIRE3        -------------------------------------------------- 134
PFTAIRE1        -------------------------------------------------- 134
PFTAIRE2        -------------------------------------------------- 134
CDC2            -------------------------------------------------- 137
1HCL            -------------------------------------------------- 132
CDK2            -------------------------------------------------- 136
CDK3            -------------------------------------------------- 136
CDK5            -------------------------------------------------- 135
CDK7            -------------------------------------------------- 138
CDK4            -------------------------------------------------- 147
1BLXA           -------------------------------------------------- 145
CDK6            -------------------------------------------------- 145
PITSLRE         -------------------------------------------------- 137
CDK10           -------------------------------------------------- 137
CDK9            -------------------------------------------------- 143
CHED            -------------------------------------------------- 145
CRK7            -------------------------------------------------- 145
CCRK            -------------------------------------------------- 136
CDK11           -------------------------------------------------- 148
CDK8            -------------------------------------------------- 148
IKKA            -KI----------------------------------------------- 145
IKKB            -RL----------------------------------------------- 146
1PHK            --M----------------------------------------------- 143
PHKG1           --M----------------------------------------------- 143
PHKG2           --M----------------------------------------------- 142
CAMK2A          -GA----------------------------------------------- 138
CAMK2B          -GA----------------------------------------------- 138
CAMK2G          -GA----------------------------------------------- 138
CAMK2D          -GA----------------------------------------------- 138
CASK            -SA----------------------------------------------- 145
1IA8A           -------------------------------------------------- 132
CHK1            -------------------------------------------------- 135
CLK1            INP----------------------------------------------- 159
CLK4            KNT----------------------------------------------- 158
CLK2            KST----------------------------------------------- 159
CLK3            KNT----------------------------------------------- 159
MAP2K5          -------------------------------------------------- 130
MAP2K3          -------------------------------------------------- 139
MAP2K6          -------------------------------------------------- 139
MAP2K4          -------------------------------------------------- 140
MAP2K7          -------------------------------------------------- 136
MAP2K1          -------------------------------------------------- 135
MAP2K2          -------------------------------------------------- 135
CDKL5           -------------------------------------------------- 135
CDKL1           -------------------------------------------------- 135
CDKL4           -------------------------------------------------- 135
CDKL2           -------------------------------------------------- 135
CDKL3           -------------------------------------------------- 134
1I09B           -------------------------------------------------- 139
GSK3B           -------------------------------------------------- 139
1J1BA           -------------------------------------------------- 139
GSK3A           -------------------------------------------------- 139
LATS1           -------------------------------------------------- 136
LATS2           -------------------------------------------------- 136
NDR1            -------------------------------------------------- 136
NDR2            -------------------------------------------------- 136
MAST1           -------------------------------------------------- 136
MAST4           -------------------------------------------------- 136
MAST2           -------------------------------------------------- 136
MAST3           -------------------------------------------------- 136
MRCKA           -------------------------------------------------- 137
MRCKB           -------------------------------------------------- 137
DMPK2           -------------------------------------------------- 137
DMPK1           -------------------------------------------------- 137
ROCK1           -------------------------------------------------- 135
ROCK2           -------------------------------------------------- 135
CRIK            -------------------------------------------------- 137
MASTL           -------------------------------------------------- 134
1O6LA           -------------------------------------------------- 136
AKT2            -------------------------------------------------- 136
AKT1            -------------------------------------------------- 137
AKT3            -------------------------------------------------- 136
MSK1            -------------------------------------------------- 141
MSK2            -------------------------------------------------- 141
P70S6K          -------------------------------------------------- 140
P70S6KB         -------------------------------------------------- 140
RSK1            -------------------------------------------------- 138
RSK3            -------------------------------------------------- 138
RSK2            -------------------------------------------------- 138
RSK4            -------------------------------------------------- 138
1FOTA           -------------------------------------------------- 136
1CDKA           -------------------------------------------------- 136
PKACA           -------------------------------------------------- 136
PKACB           -------------------------------------------------- 136
PKACG           -------------------------------------------------- 136
PRKX            -------------------------------------------------- 136
PRKY            -------------------------------------------------- 136
PKCA            -------------------------------------------------- 137
PKCB            -------------------------------------------------- 137
PKCG            -------------------------------------------------- 142
PKCE            -------------------------------------------------- 137
PKCH            -------------------------------------------------- 137
PKCD            -------------------------------------------------- 137
PKCT            -------------------------------------------------- 137
PKCI            -------------------------------------------------- 137
PKCZ            -------------------------------------------------- 137
PKN1            -------------------------------------------------- 138
PKN2            -------------------------------------------------- 138
PKN3            -------------------------------------------------- 138
SGK             -------------------------------------------------- 137
SGK2            -------------------------------------------------- 137
SGK3            -------------------------------------------------- 137
PKG1            -------------------------------------------------- 137
PKG2            -------------------------------------------------- 136
AURB            -------------------------------------------------- 136
AURC            -------------------------------------------------- 136
AURA            -------------------------------------------------- 136
AURORA2_AVE     -------------------------------------------------- 136
PLK1            -------------------------------------------------- 136
PLK2            -------------------------------------------------- 136
PLK3            -------------------------------------------------- 136
PLK4            -------------------------------------------------- 137
NEK11           -------------------------------------------------- 142
YANK1           -------------------------------------------------- 136
YANK2           -------------------------------------------------- 136
YANK3           -------------------------------------------------- 136
SGK494          -------------------------------------------------- 135
DOMAIN2_MSK1    -------------------------------------------------- 134
DOMAIN2_MSK2    -------------------------------------------------- 129
DOMAIN2_RSK1    -------------------------------------------------- 134
DOMAIN2_RSK2    -------------------------------------------------- 134
DOMAIN2_RSK3    -------------------------------------------------- 134
DOMAIN2_RSK4    -------------------------------------------------- 134
DRAK1           -------------------------------------------------- 141
DRAK2           -------------------------------------------------- 141
1JKSA           -------------------------------------------------- 143
DAPK1           -------------------------------------------------- 143
DAPK3           -------------------------------------------------- 143
DAPK2           -------------------------------------------------- 143
SGK085          -------------------------------------------------- 136
CAMLCK          -------------------------------------------------- 136
SKMLCK          -------------------------------------------------- 136
SMMLCK          -------------------------------------------------- 136
1KOBA           -------------------------------------------------- 136
1TKIA           -------------------------------------------------- 135
TTN             -------------------------------------------------- 135
PKD1            -------------------------------------------------- 139
PKD3            -------------------------------------------------- 139
PKD2            -------------------------------------------------- 139
PSKH1           -------------------------------------------------- 136
PSKH2           -------------------------------------------------- 136
CAMK1A          -------------------------------------------------- 137
CAMK1D          -------------------------------------------------- 137
CAMK1B          -------------------------------------------------- 137
CAMK1G          -------------------------------------------------- 136
CAMK4           -------------------------------------------------- 134
DCAMKL1         -------------------------------------------------- 138
DCAMKL2         -------------------------------------------------- 138
DCAMKL3         -------------------------------------------------- 138
CHK2            -------------------------------------------------- 143
MAPKAPK2        -------------------------------------------------- 138
MAPKAPK3        -------------------------------------------------- 138
MAPKAPK5        -------------------------------------------------- 142
MNK1            -------------------------------------------------- 138
MNK2            -------------------------------------------------- 137
VACAMKL         -------------------------------------------------- 137
GCK             -------------------------------------------------- 134
KHS1            -------------------------------------------------- 134
KHS2            -------------------------------------------------- 134
HPK1            -------------------------------------------------- 134
MST1            -------------------------------------------------- 133
MST2            -------------------------------------------------- 133
MST3            -------------------------------------------------- 134
YSK1            -------------------------------------------------- 134
MST4            -------------------------------------------------- 134
LOK             -------------------------------------------------- 135
SLK             -------------------------------------------------- 135
MAP3K4          -------------------------------------------------- 134
MAP3K2          -------------------------------------------------- 141
MAP3K3          -------------------------------------------------- 141
MAP3K8          -------------------------------------------------- 139
MAP3K5          -------------------------------------------------- 143
MAP3K7          -------------------------------------------------- 134
MAP3K6          -------------------------------------------------- 133
PAK1            -------------------------------------------------- 133
PAK3            -------------------------------------------------- 133
PAK2            -------------------------------------------------- 134
PAK4            -------------------------------------------------- 133
PAK5            -------------------------------------------------- 133
PAK6            -------------------------------------------------- 133
OSR1            -------------------------------------------------- 143
STLK3           -------------------------------------------------- 143
TAO1            -------------------------------------------------- 137
TAO3            -------------------------------------------------- 137
TAO2            -------------------------------------------------- 137
MYO3A           -------------------------------------------------- 143
MYO3B           -------------------------------------------------- 143
ZC1/HGK         -------------------------------------------------- 142
ZC3/MINK        -------------------------------------------------- 142
ZC2/TNIK        -------------------------------------------------- 142
ZC4/NRK         -------------------------------------------------- 166
MAP3K1          -------------------------------------------------- 140
GAK             -------------------------------------------------- 147
SGK495          -------------------------------------------------- 53
TRB1            -------------------------------------------------- 121
TRB2            -------------------------------------------------- 126
TRB3            -------------------------------------------------- 124
SSTK            -------------------------------------------------- 138
TSSK3           -------------------------------------------------- 137
TSSK1           -------------------------------------------------- 138
TSSK2           -------------------------------------------------- 138
TSSK4           -------------------------------------------------- 137
HUNK            -------------------------------------------------- 139
SNRK            -------------------------------------------------- 138
NIM1            -------------------------------------------------- 136
MELK            -------------------------------------------------- 135
BRSK1           -------------------------------------------------- 136
BRSK2           -------------------------------------------------- 136
MARK1           -------------------------------------------------- 136
MARK2           -------------------------------------------------- 136
MARK3           -------------------------------------------------- 136
MARK4           -------------------------------------------------- 136
QIK             -------------------------------------------------- 136
SIK             -------------------------------------------------- 136
QSK             -------------------------------------------------- 136
AMPKA1          -------------------------------------------------- 137
AMPKA2          -------------------------------------------------- 137
NUAK1           -------------------------------------------------- 137
NUAK2           -------------------------------------------------- 136
BIKE            -------------------------------------------------- 143
AAK1            -------------------------------------------------- 144
LIMK1           -------------------------------------------------- 135
LIMK2           -------------------------------------------------- 134
TESK1           -------------------------------------------------- 135
TESK2           -------------------------------------------------- 115
WNK1            -------------------------------------------------- 143
WNK3            -------------------------------------------------- 143
WNK2            -------------------------------------------------- 143
WNK4            -------------------------------------------------- 143
NEK10           -------------------------------------------------- 150
NEK6            -------------------------------------------------- 141
NEK7            -------------------------------------------------- 141
NEK2            -------------------------------------------------- 147
NEK1            -------------------------------------------------- 138
NEK5            -------------------------------------------------- 138
NEK3            -------------------------------------------------- 137
NEK4            -------------------------------------------------- 139
NEK8            -------------------------------------------------- 139
NEK9            -------------------------------------------------- 138
NRBP1           -------------------------------------------------- 151
NRBP2           -------------------------------------------------- 151
CLIK1           -------------------------------------------------- 174
CLIK1L          -------------------------------------------------- 177
STK33           -------------------------------------------------- 144
DOMAIN2_GCN2    -------------------------------------------------- 159
SCYL1           -------------------------------------------------- 126
SCYL3           -------------------------------------------------- 113
DOMAIN2_JAK1    -------------------------------------------------- 146
DOMAIN2_TYK2    -------------------------------------------------- 160
DOMAIN2_JAK2    -------------------------------------------------- 144
DOMAIN2_JAK3    -------------------------------------------------- 140
ILK             -------------------------------------------------- 140
LRRK1           -------------------------------------------------- 159
PBK             -------------------------------------------------- 148
WEE1            -------------------------------------------------- 142
WEE1B           -------------------------------------------------- 145
SGK071          -------------------------------------------------- 143
PIK3R4          -------------------------------------------------- 136
MSSK1           GAPPPSRSIVSTAPQEVLTGKLSKNKRKKMRRKRKQQKRLLEERLRDLQR 212
SRPK1           GAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEE 212
SRPK2           GAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEE 212
RSKL1           -------------------------------------------------- 121
RSKL2           -------------------------------------------------- 273
SGK396          -------------------------------------------------- 135
VRK1            -------------------------------------------------- 155
VRK2            -------------------------------------------------- 152
VRK3            -------------------------------------------------- 100
BUB1            -------------------------------------------------- 149
BUBR1           -------------------------------------------------- 148
SGK196          -------------------------------------------------- 135
SGK493          -------------------------------------------------- 150
                                                                  

DYRK1A          -------------------------------------------------- 144
DYRK1B          -------------------------------------------------- 144
DYRK2           -------------------------------------------------- 142
DYRK3           -------------------------------------------------- 142
DYRK4           -------------------------------------------------- 142
HIPK1           -------------------------------------------------- 142
HIPK2           -------------------------------------------------- 142
HIPK3           -------------------------------------------------- 142
HIPK4           -------------------------------------------------- 142
PRP4            -------------------------------------------------- 142
MOK             -------------------------------------------------- 136
1A6O            -------------------------------------------------- 131
1LPUA           -------------------------------------------------- 131
CK2A1           -------------------------------------------------- 131
CK2A1-RS        -------------------------------------------------- 131
CK2A2           -------------------------------------------------- 131
HSER            -------------------------------------------------- 138
SLOB            -------------------------------------------------- 157
CDC7            -------------------------------------------------- 133
1CSN            -------------------------------------------------- 137
CK1G1           -------------------------------------------------- 138
CK1G3           -------------------------------------------------- 137
CK1G2           -------------------------------------------------- 137
CK1A            -------------------------------------------------- 135
CK1A2           -------------------------------------------------- 135
1CKJA           -------------------------------------------------- 135
CK1D            -------------------------------------------------- 135
CK1E            -------------------------------------------------- 135
TTBK1           -------------------------------------------------- 137
TTBK2           -------------------------------------------------- 137
TLK1            -------------------------------------------------- 146
TLK2            -------------------------------------------------- 146
GPRK4           -------------------------------------------------- 138
GPRK6           -------------------------------------------------- 138
GPRK5           -------------------------------------------------- 138
RHOK            -------------------------------------------------- 140
GPRK7           -------------------------------------------------- 138
BARK1           -------------------------------------------------- 139
BARK2           -------------------------------------------------- 139
TTK             -------------------------------------------------- 134
RIPK1           -------------------------------------------------- 134
HASPIN          -------------------------------------------------- 198
GCN2            -------------------------------------------------- 271
HRI             -------------------------------------------------- 289
KIS             -------------------------------------------------- 149
PDK1            -------------------------------------------------- 136
PKR             -------------------------------------------------- 160
PEK             -------------------------------------------------- 357
PRPK            -------------------------------------------------- 145
DOMAIN2_OBSCN   -------------------------------------------------- 132
DOMAIN2_SPEG    -------------------------------------------------- 132
LMR1            -------------------------------------------------- 141
LMR2            -------------------------------------------------- 141
LMR3            -------------------------------------------------- 146
SGK307          -------------------------------------------------- 49
STLK5           -------------------------------------------------- 139
STLK6           -------------------------------------------------- 139
STLK6-RS        -------------------------------------------------- 139
OBSCN           -------------------------------------------------- 134
SPEG            -------------------------------------------------- 135
TRAD            -------------------------------------------------- 135
TRIO            -------------------------------------------------- 135
SGK223          -------------------------------------------------- 140
SGK269          -------------------------------------------------- 141
ALK1            -------------------------------------------------- 141
ALK2            -------------------------------------------------- 141
IRAK4           -------------------------------------------------- 138
BMPR2           -------------------------------------------------- 143
TGFBR2          -------------------------------------------------- 148
ACTR2           -------------------------------------------------- 143
ACTR2B          -------------------------------------------------- 144
1B6CB           -------------------------------------------------- 141
TGFBR1          -------------------------------------------------- 141
ALK4            -------------------------------------------------- 141
ALK7            -------------------------------------------------- 141
BMPR1A          -------------------------------------------------- 141
BMPR1B          -------------------------------------------------- 141
IRAK1           -------------------------------------------------- 141
IRAK2           -------------------------------------------------- 138
IRAK3           -------------------------------------------------- 141
MISR2           -------------------------------------------------- 143
MYT1            -------------------------------------------------- 136
SBK             -------------------------------------------------- 136
SGK110          -------------------------------------------------- 135
SGK069          -------------------------------------------------- 136
SGK496          -------------------------------------------------- 138
NIK             -------------------------------------------------- 129
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 150
IKKE            -------------------------------------------------- 143
TBK1            -------------------------------------------------- 143
MOS             -------------------------------------------------- 154
LKB1            -------------------------------------------------- 140
CAMKK1          -------------------------------------------------- 168
CAMKK2          -------------------------------------------------- 160
PASK            -------------------------------------------------- 142
PIM1            -------------------------------------------------- 143
PIM3            -------------------------------------------------- 144
PIM2            -------------------------------------------------- 145
COT             -------------------------------------------------- 130
SCYL2           -------------------------------------------------- 159
FUSED           -------------------------------------------------- 134
ULK1            -------------------------------------------------- 144
ULK2            -------------------------------------------------- 144
ULK3            -------------------------------------------------- 138
ULK4            -------------------------------------------------- 115
IRE1            -------------------------------------------------- 135
IRE2            -------------------------------------------------- 135
RNASEL          -------------------------------------------------- 129
MPSK1           -------------------------------------------------- 141
PINK1           -------------------------------------------------- 223
ALK             -------------------------------------------------- 149
LTK             -------------------------------------------------- 149
ROS             -------------------------------------------------- 152
IGF1R           -------------------------------------------------- 149
1IR3A           -------------------------------------------------- 149
INSR            -------------------------------------------------- 149
IRR             -------------------------------------------------- 149
1M14A           -------------------------------------------------- 138
EGFR            -------------------------------------------------- 138
HER2/ERBB2      -------------------------------------------------- 138
HER4/ERBB4      -------------------------------------------------- 138
HER3/ERBB3      -------------------------------------------------- 138
ITK             -------------------------------------------------- 132
TEC             -------------------------------------------------- 132
TXK             -------------------------------------------------- 132
BMX             -------------------------------------------------- 132
1K2PA           -------------------------------------------------- 132
BTK             -------------------------------------------------- 132
CCK4            -------------------------------------------------- 147
ROR1            -------------------------------------------------- 155
ROR2            -------------------------------------------------- 155
MUSK            -------------------------------------------------- 163
TRKA            -------------------------------------------------- 153
TRKB            -------------------------------------------------- 151
TRKC            -------------------------------------------------- 154
DDR1            -------------------------------------------------- 169
DDR2            -------------------------------------------------- 160
RYK             -------------------------------------------------- 148
JAK1            -------------------------------------------------- 140
JAK2            -------------------------------------------------- 140
JAK3            -------------------------------------------------- 140
ACK             -------------------------------------------------- 139
TYK2            -------------------------------------------------- 139
TNK1            -------------------------------------------------- 142
EPHA1           -------------------------------------------------- 138
EPHA10          -------------------------------------------------- 138
FAK             -------------------------------------------------- 137
EPHB6           -------------------------------------------------- 138
EPHA2           -------------------------------------------------- 139
EPHA8           -------------------------------------------------- 138
EPHA6           -------------------------------------------------- 180
EPHB1           -------------------------------------------------- 138
EPHB2           -------------------------------------------------- 138
EPHB3           -------------------------------------------------- 138
EPHB4           -------------------------------------------------- 138
EPHA7           -------------------------------------------------- 138
EPHA4           -------------------------------------------------- 138
EPHA3           -------------------------------------------------- 138
EPHA5           -------------------------------------------------- 138
PYK2            -------------------------------------------------- 137
CSK             -------------------------------------------------- 132
CTK             -------------------------------------------------- 130
1IEPA           -------------------------------------------------- 134
ABL             -------------------------------------------------- 134
ARG             -------------------------------------------------- 134
BRK             -------------------------------------------------- 134
SRM             -------------------------------------------------- 133
FRK             -------------------------------------------------- 133
FGR             -------------------------------------------------- 132
FYN             -------------------------------------------------- 132
SRC             -------------------------------------------------- 132
YES             -------------------------------------------------- 132
HCK             -------------------------------------------------- 132
LYN             -------------------------------------------------- 133
3LCK            -------------------------------------------------- 132
LCK             -------------------------------------------------- 132
BLK             -------------------------------------------------- 132
FER             -------------------------------------------------- 134
FES             -------------------------------------------------- 135
SYK             -------------------------------------------------- 136
ZAP70           -------------------------------------------------- 136
FGFR1           -------------------------------------------------- 158
FGFR2           -------------------------------------------------- 158
FGFR3           -------------------------------------------------- 158
FGFR4           -------------------------------------------------- 158
RET             -------------------------------------------------- 163
TIE1            -------------------------------------------------- 153
1FVRA           -------------------------------------------------- 153
TIE2            -------------------------------------------------- 153
FLT1            -------------------------------------------------- 208
KDR             -------------------------------------------------- 207
KDR_AVE         -------------------------------------------------- 150
FLT4            -------------------------------------------------- 205
FMS             -------------------------------------------------- 209
FLT3            -------------------------------------------------- 214
KIT             -------------------------------------------------- 216
PDGFRA          -------------------------------------------------- 238
PDGFRB          -------------------------------------------------- 239
MER             -------------------------------------------------- 149
AXL             -------------------------------------------------- 149
TYRO3           -------------------------------------------------- 150
MET             -------------------------------------------------- 139
RON             -------------------------------------------------- 139
HH498           -------------------------------------------------- 138
LZK             -------------------------------------------------- 124
DLK             -------------------------------------------------- 124
MLK1            -------------------------------------------------- 145
MLK3            -------------------------------------------------- 145
MLK2            -------------------------------------------------- 145
MLK4            -------------------------------------------------- 160
ZAK             -------------------------------------------------- 130
TAK1            -------------------------------------------------- 134
KSR1            -------------------------------------------------- 132
KSR2            -------------------------------------------------- 132
ARAF            -------------------------------------------------- 132
RAF1            -------------------------------------------------- 132
BRAF            -------------------------------------------------- 132
LRRK2           -------------------------------------------------- 133
ANKRD3          -------------------------------------------------- 134
SGK288          -------------------------------------------------- 133
RIPK2           -------------------------------------------------- 141
RIPK3           -------------------------------------------------- 134
MLKL            -------------------------------------------------- 136
ANPA            -------------------------------------------------- 138
ANPB            -------------------------------------------------- 138
CYGD            -------------------------------------------------- 146
CYGF            -------------------------------------------------- 151
TBCK            -------------------------------------------------- 111
ERK1            -------------------------------------------------- 137
3ERK            -------------------------------------------------- 137
ERK2            -------------------------------------------------- 137
ERK5            -------------------------------------------------- 140
1JNK            -------------------------------------------------- 138
1PMNA           -------------------------------------------------- 138
JNK3            -------------------------------------------------- 138
JNK1            -------------------------------------------------- 138
JNK2            -------------------------------------------------- 138
1P38            -------------------------------------------------- 139
P38A            -------------------------------------------------- 139
P38B            -------------------------------------------------- 147
P38D            -------------------------------------------------- 138
P38G            -------------------------------------------------- 139
NLK             -------------------------------------------------- 139
ERK7            -------------------------------------------------- 156
ERK3            -------------------------------------------------- 146
ERK4            -------------------------------------------------- 143
ICK             -------------------------------------------------- 134
MAK             -------------------------------------------------- 134
PCTAIRE1        -------------------------------------------------- 134
PCTAIRE2        -------------------------------------------------- 134
PCTAIRE3        -------------------------------------------------- 134
PFTAIRE1        -------------------------------------------------- 134
PFTAIRE2        -------------------------------------------------- 134
CDC2            -------------------------------------------------- 137
1HCL            -------------------------------------------------- 132
CDK2            -------------------------------------------------- 136
CDK3            -------------------------------------------------- 136
CDK5            -------------------------------------------------- 135
CDK7            -------------------------------------------------- 138
CDK4            -------------------------------------------------- 147
1BLXA           -------------------------------------------------- 145
CDK6            -------------------------------------------------- 145
PITSLRE         -------------------------------------------------- 137
CDK10           -------------------------------------------------- 137
CDK9            -------------------------------------------------- 143
CHED            -------------------------------------------------- 145
CRK7            -------------------------------------------------- 145
CCRK            -------------------------------------------------- 136
CDK11           -------------------------------------------------- 148
CDK8            -------------------------------------------------- 148
IKKA            -------------------------------------------------- 145
IKKB            -------------------------------------------------- 146
1PHK            -------------------------------------------------- 143
PHKG1           -------------------------------------------------- 143
PHKG2           -------------------------------------------------- 142
CAMK2A          -------------------------------------------------- 138
CAMK2B          -------------------------------------------------- 138
CAMK2G          -------------------------------------------------- 138
CAMK2D          -------------------------------------------------- 138
CASK            -------------------------------------------------- 145
1IA8A           -------------------------------------------------- 132
CHK1            -------------------------------------------------- 135
CLK1            -------------------------------------------------- 159
CLK4            -------------------------------------------------- 158
CLK2            -------------------------------------------------- 159
CLK3            -------------------------------------------------- 159
MAP2K5          -------------------------------------------------- 130
MAP2K3          -------------------------------------------------- 139
MAP2K6          -------------------------------------------------- 139
MAP2K4          -------------------------------------------------- 140
MAP2K7          -------------------------------------------------- 136
MAP2K1          -------------------------------------------------- 135
MAP2K2          -------------------------------------------------- 135
CDKL5           -------------------------------------------------- 135
CDKL1           -------------------------------------------------- 135
CDKL4           -------------------------------------------------- 135
CDKL2           -------------------------------------------------- 135
CDKL3           -------------------------------------------------- 134
1I09B           -------------------------------------------------- 139
GSK3B           -------------------------------------------------- 139
1J1BA           -------------------------------------------------- 139
GSK3A           -------------------------------------------------- 139
LATS1           -------------------------------------------------- 136
LATS2           -------------------------------------------------- 136
NDR1            -------------------------------------------------- 136
NDR2            -------------------------------------------------- 136
MAST1           -------------------------------------------------- 136
MAST4           -------------------------------------------------- 136
MAST2           -------------------------------------------------- 136
MAST3           -------------------------------------------------- 136
MRCKA           -------------------------------------------------- 137
MRCKB           -------------------------------------------------- 137
DMPK2           -------------------------------------------------- 137
DMPK1           -------------------------------------------------- 137
ROCK1           -------------------------------------------------- 135
ROCK2           -------------------------------------------------- 135
CRIK            -------------------------------------------------- 137
MASTL           -------------------------------------------------- 134
1O6LA           -------------------------------------------------- 136
AKT2            -------------------------------------------------- 136
AKT1            -------------------------------------------------- 137
AKT3            -------------------------------------------------- 136
MSK1            -------------------------------------------------- 141
MSK2            -------------------------------------------------- 141
P70S6K          -------------------------------------------------- 140
P70S6KB         -------------------------------------------------- 140
RSK1            -------------------------------------------------- 138
RSK3            -------------------------------------------------- 138
RSK2            -------------------------------------------------- 138
RSK4            -------------------------------------------------- 138
1FOTA           -------------------------------------------------- 136
1CDKA           -------------------------------------------------- 136
PKACA           -------------------------------------------------- 136
PKACB           -------------------------------------------------- 136
PKACG           -------------------------------------------------- 136
PRKX            -------------------------------------------------- 136
PRKY            -------------------------------------------------- 136
PKCA            -------------------------------------------------- 137
PKCB            -------------------------------------------------- 137
PKCG            -------------------------------------------------- 142
PKCE            -------------------------------------------------- 137
PKCH            -------------------------------------------------- 137
PKCD            -------------------------------------------------- 137
PKCT            -------------------------------------------------- 137
PKCI            -------------------------------------------------- 137
PKCZ            -------------------------------------------------- 137
PKN1            -------------------------------------------------- 138
PKN2            -------------------------------------------------- 138
PKN3            -------------------------------------------------- 138
SGK             -------------------------------------------------- 137
SGK2            -------------------------------------------------- 137
SGK3            -------------------------------------------------- 137
PKG1            -------------------------------------------------- 137
PKG2            -------------------------------------------------- 136
AURB            -------------------------------------------------- 136
AURC            -------------------------------------------------- 136
AURA            -------------------------------------------------- 136
AURORA2_AVE     -------------------------------------------------- 136
PLK1            -------------------------------------------------- 136
PLK2            -------------------------------------------------- 136
PLK3            -------------------------------------------------- 136
PLK4            -------------------------------------------------- 137
NEK11           -------------------------------------------------- 142
YANK1           -------------------------------------------------- 136
YANK2           -------------------------------------------------- 136
YANK3           -------------------------------------------------- 136
SGK494          -------------------------------------------------- 135
DOMAIN2_MSK1    -------------------------------------------------- 134
DOMAIN2_MSK2    -------------------------------------------------- 129
DOMAIN2_RSK1    -------------------------------------------------- 134
DOMAIN2_RSK2    -------------------------------------------------- 134
DOMAIN2_RSK3    -------------------------------------------------- 134
DOMAIN2_RSK4    -------------------------------------------------- 134
DRAK1           -------------------------------------------------- 141
DRAK2           -------------------------------------------------- 141
1JKSA           -------------------------------------------------- 143
DAPK1           -------------------------------------------------- 143
DAPK3           -------------------------------------------------- 143
DAPK2           -------------------------------------------------- 143
SGK085          -------------------------------------------------- 136
CAMLCK          -------------------------------------------------- 136
SKMLCK          -------------------------------------------------- 136
SMMLCK          -------------------------------------------------- 136
1KOBA           -------------------------------------------------- 136
1TKIA           -------------------------------------------------- 135
TTN             -------------------------------------------------- 135
PKD1            -------------------------------------------------- 139
PKD3            -------------------------------------------------- 139
PKD2            -------------------------------------------------- 139
PSKH1           -------------------------------------------------- 136
PSKH2           -------------------------------------------------- 136
CAMK1A          -------------------------------------------------- 137
CAMK1D          -------------------------------------------------- 137
CAMK1B          -------------------------------------------------- 137
CAMK1G          -------------------------------------------------- 136
CAMK4           -------------------------------------------------- 134
DCAMKL1         -------------------------------------------------- 138
DCAMKL2         -------------------------------------------------- 138
DCAMKL3         -------------------------------------------------- 138
CHK2            -------------------------------------------------- 143
MAPKAPK2        -------------------------------------------------- 138
MAPKAPK3        -------------------------------------------------- 138
MAPKAPK5        -------------------------------------------------- 142
MNK1            -------------------------------------------------- 138
MNK2            -------------------------------------------------- 137
VACAMKL         -------------------------------------------------- 137
GCK             -------------------------------------------------- 134
KHS1            -------------------------------------------------- 134
KHS2            -------------------------------------------------- 134
HPK1            -------------------------------------------------- 134
MST1            -------------------------------------------------- 133
MST2            -------------------------------------------------- 133
MST3            -------------------------------------------------- 134
YSK1            -------------------------------------------------- 134
MST4            -------------------------------------------------- 134
LOK             -------------------------------------------------- 135
SLK             -------------------------------------------------- 135
MAP3K4          -------------------------------------------------- 134
MAP3K2          -------------------------------------------------- 141
MAP3K3          -------------------------------------------------- 141
MAP3K8          -------------------------------------------------- 139
MAP3K5          -------------------------------------------------- 143
MAP3K7          -------------------------------------------------- 134
MAP3K6          -------------------------------------------------- 133
PAK1            -------------------------------------------------- 133
PAK3            -------------------------------------------------- 133
PAK2            -------------------------------------------------- 134
PAK4            -------------------------------------------------- 133
PAK5            -------------------------------------------------- 133
PAK6            -------------------------------------------------- 133
OSR1            -------------------------------------------------- 143
STLK3           -------------------------------------------------- 143
TAO1            -------------------------------------------------- 137
TAO3            -------------------------------------------------- 137
TAO2            -------------------------------------------------- 137
MYO3A           -------------------------------------------------- 143
MYO3B           -------------------------------------------------- 143
ZC1/HGK         -------------------------------------------------- 142
ZC3/MINK        -------------------------------------------------- 142
ZC2/TNIK        -------------------------------------------------- 142
ZC4/NRK         -------------------------------------------------- 166
MAP3K1          -------------------------------------------------- 140
GAK             -------------------------------------------------- 147
SGK495          -------------------------------------------------- 53
TRB1            -------------------------------------------------- 121
TRB2            -------------------------------------------------- 126
TRB3            -------------------------------------------------- 124
SSTK            -------------------------------------------------- 138
TSSK3           -------------------------------------------------- 137
TSSK1           -------------------------------------------------- 138
TSSK2           -------------------------------------------------- 138
TSSK4           -------------------------------------------------- 137
HUNK            -------------------------------------------------- 139
SNRK            -------------------------------------------------- 138
NIM1            -------------------------------------------------- 136
MELK            -------------------------------------------------- 135
BRSK1           -------------------------------------------------- 136
BRSK2           -------------------------------------------------- 136
MARK1           -------------------------------------------------- 136
MARK2           -------------------------------------------------- 136
MARK3           -------------------------------------------------- 136
MARK4           -------------------------------------------------- 136
QIK             -------------------------------------------------- 136
SIK             -------------------------------------------------- 136
QSK             -------------------------------------------------- 136
AMPKA1          -------------------------------------------------- 137
AMPKA2          -------------------------------------------------- 137
NUAK1           -------------------------------------------------- 137
NUAK2           -------------------------------------------------- 136
BIKE            -------------------------------------------------- 143
AAK1            -------------------------------------------------- 144
LIMK1           -------------------------------------------------- 135
LIMK2           -------------------------------------------------- 134
TESK1           -------------------------------------------------- 135
TESK2           -------------------------------------------------- 115
WNK1            -------------------------------------------------- 143
WNK3            -------------------------------------------------- 143
WNK2            -------------------------------------------------- 143
WNK4            -------------------------------------------------- 143
NEK10           -------------------------------------------------- 150
NEK6            -------------------------------------------------- 141
NEK7            -------------------------------------------------- 141
NEK2            -------------------------------------------------- 147
NEK1            -------------------------------------------------- 138
NEK5            -------------------------------------------------- 138
NEK3            -------------------------------------------------- 137
NEK4            -------------------------------------------------- 139
NEK8            -------------------------------------------------- 139
NEK9            -------------------------------------------------- 138
NRBP1           -------------------------------------------------- 151
NRBP2           -------------------------------------------------- 151
CLIK1           -------------------------------------------------- 174
CLIK1L          -------------------------------------------------- 177
STK33           -------------------------------------------------- 144
DOMAIN2_GCN2    -------------------------------------------------- 159
SCYL1           -------------------------------------------------- 126
SCYL3           -------------------------------------------------- 113
DOMAIN2_JAK1    -------------------------------------------------- 146
DOMAIN2_TYK2    -------------------------------------------------- 160
DOMAIN2_JAK2    -------------------------------------------------- 144
DOMAIN2_JAK3    -------------------------------------------------- 140
ILK             -------------------------------------------------- 140
LRRK1           -------------------------------------------------- 159
PBK             -------------------------------------------------- 148
WEE1            -------------------------------------------------- 142
WEE1B           -------------------------------------------------- 145
SGK071          -------------------------------------------------- 143
PIK3R4          -------------------------------------------------- 136
MSSK1           LEAMEAAT------------------------------------------ 220
SRPK1           MEKES-------GPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESS 255
SRPK2           LEREAERKIIEENITSAAPSNDQDGEYCPEVKLKTTGLEEAAEAETAKDN 262
RSKL1           -------------------------------------------------- 121
RSKL2           -------------------------------------------------- 273
SGK396          -------------------------------------------------- 135
VRK1            -------------------------------------------------- 155
VRK2            -------------------------------------------------- 152
VRK3            -------------------------------------------------- 100
BUB1            -------------------------------------------------- 149
BUBR1           -------------------------------------------------- 148
SGK196          -------------------------------------------------- 135
SGK493          -------------------------------------------------- 150
                                                                  

DYRK1A          -------------------------------------------------- 144
DYRK1B          -------------------------------------------------- 144
DYRK2           -------------------------------------------------- 142
DYRK3           -------------------------------------------------- 142
DYRK4           -------------------------------------------------- 142
HIPK1           -------------------------------------------------- 142
HIPK2           -------------------------------------------------- 142
HIPK3           -------------------------------------------------- 142
HIPK4           -------------------------------------------------- 142
PRP4            -------------------------------------------------- 142
MOK             -------------------------------------------------- 136
1A6O            -------------------------------------------------- 131
1LPUA           -------------------------------------------------- 131
CK2A1           -------------------------------------------------- 131
CK2A1-RS        -------------------------------------------------- 131
CK2A2           -------------------------------------------------- 131
HSER            -------------------------------------------------- 138
SLOB            -------------------------------------------------- 157
CDC7            -------------------------------------------------- 133
1CSN            -------------------------------------------------- 137
CK1G1           -------------------------------------------------- 138
CK1G3           -------------------------------------------------- 137
CK1G2           -------------------------------------------------- 137
CK1A            -------------------------------------------------- 135
CK1A2           -------------------------------------------------- 135
1CKJA           -------------------------------------------------- 135
CK1D            -------------------------------------------------- 135
CK1E            -------------------------------------------------- 135
TTBK1           -------------------------------------------------- 137
TTBK2           -------------------------------------------------- 137
TLK1            -------------------------------------------------- 146
TLK2            -------------------------------------------------- 146
GPRK4           -------------------------------------------------- 138
GPRK6           -------------------------------------------------- 138
GPRK5           -------------------------------------------------- 138
RHOK            -------------------------------------------------- 140
GPRK7           -------------------------------------------------- 138
BARK1           -------------------------------------------------- 139
BARK2           -------------------------------------------------- 139
TTK             -------------------------------------------------- 134
RIPK1           -------------------------------------------------- 134
HASPIN          -------------------------------------------------- 198
GCN2            -------------------------------------------------- 271
HRI             -------------------------------------------------- 289
KIS             -------------------------------------------------- 149
PDK1            -------------------------------------------------- 136
PKR             -------------------------------------------------- 160
PEK             -------------------------------------------------- 357
PRPK            -------------------------------------------------- 145
DOMAIN2_OBSCN   -------------------------------------------------- 132
DOMAIN2_SPEG    -------------------------------------------------- 132
LMR1            -------------------------------------------------- 141
LMR2            -------------------------------------------------- 141
LMR3            -------------------------------------------------- 146
SGK307          -------------------------------------------------- 49
STLK5           -------------------------------------------------- 139
STLK6           -------------------------------------------------- 139
STLK6-RS        -------------------------------------------------- 139
OBSCN           -------------------------------------------------- 134
SPEG            -------------------------------------------------- 135
TRAD            -------------------------------------------------- 135
TRIO            -------------------------------------------------- 135
SGK223          -------------------------------------------------- 140
SGK269          -------------------------------------------------- 141
ALK1            -------------------------------------------------- 141
ALK2            -------------------------------------------------- 141
IRAK4           -------------------------------------------------- 138
BMPR2           -------------------------------------------------- 143
TGFBR2          -------------------------------------------------- 148
ACTR2           -------------------------------------------------- 143
ACTR2B          -------------------------------------------------- 144
1B6CB           -------------------------------------------------- 141
TGFBR1          -------------------------------------------------- 141
ALK4            -------------------------------------------------- 141
ALK7            -------------------------------------------------- 141
BMPR1A          -------------------------------------------------- 141
BMPR1B          -------------------------------------------------- 141
IRAK1           -------------------------------------------------- 141
IRAK2           -------------------------------------------------- 138
IRAK3           -------------------------------------------------- 141
MISR2           -------------------------------------------------- 143
MYT1            -------------------------------------------------- 136
SBK             -------------------------------------------------- 136
SGK110          -------------------------------------------------- 135
SGK069          -------------------------------------------------- 136
SGK496          -------------------------------------------------- 138
NIK             -------------------------------------------------- 129
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 150
IKKE            -------------------------------------------------- 143
TBK1            -------------------------------------------------- 143
MOS             -------------------------------------------------- 154
LKB1            -------------------------------------------------- 140
CAMKK1          -------------------------------------------------- 168
CAMKK2          -------------------------------------------------- 160
PASK            -------------------------------------------------- 142
PIM1            -------------------------------------------------- 143
PIM3            -------------------------------------------------- 144
PIM2            -------------------------------------------------- 145
COT             -------------------------------------------------- 130
SCYL2           -------------------------------------------------- 159
FUSED           -------------------------------------------------- 134
ULK1            -------------------------------------------------- 144
ULK2            -------------------------------------------------- 144
ULK3            -------------------------------------------------- 138
ULK4            -------------------------------------------------- 115
IRE1            -------------------------------------------------- 135
IRE2            -------------------------------------------------- 135
RNASEL          -------------------------------------------------- 129
MPSK1           -------------------------------------------------- 141
PINK1           -------------------------------------------------- 223
ALK             -------------------------------------------------- 149
LTK             -------------------------------------------------- 149
ROS             -------------------------------------------------- 152
IGF1R           -------------------------------------------------- 149
1IR3A           -------------------------------------------------- 149
INSR            -------------------------------------------------- 149
IRR             -------------------------------------------------- 149
1M14A           -------------------------------------------------- 138
EGFR            -------------------------------------------------- 138
HER2/ERBB2      -------------------------------------------------- 138
HER4/ERBB4      -------------------------------------------------- 138
HER3/ERBB3      -------------------------------------------------- 138
ITK             -------------------------------------------------- 132
TEC             -------------------------------------------------- 132
TXK             -------------------------------------------------- 132
BMX             -------------------------------------------------- 132
1K2PA           -------------------------------------------------- 132
BTK             -------------------------------------------------- 132
CCK4            -------------------------------------------------- 147
ROR1            -------------------------------------------------- 155
ROR2            -------------------------------------------------- 155
MUSK            -------------------------------------------------- 163
TRKA            -------------------------------------------------- 153
TRKB            -------------------------------------------------- 151
TRKC            -------------------------------------------------- 154
DDR1            -------------------------------------------------- 169
DDR2            -------------------------------------------------- 160
RYK             -------------------------------------------------- 148
JAK1            -------------------------------------------------- 140
JAK2            -------------------------------------------------- 140
JAK3            -------------------------------------------------- 140
ACK             -------------------------------------------------- 139
TYK2            -------------------------------------------------- 139
TNK1            -------------------------------------------------- 142
EPHA1           -------------------------------------------------- 138
EPHA10          -------------------------------------------------- 138
FAK             -------------------------------------------------- 137
EPHB6           -------------------------------------------------- 138
EPHA2           -------------------------------------------------- 139
EPHA8           -------------------------------------------------- 138
EPHA6           -------------------------------------------------- 180
EPHB1           -------------------------------------------------- 138
EPHB2           -------------------------------------------------- 138
EPHB3           -------------------------------------------------- 138
EPHB4           -------------------------------------------------- 138
EPHA7           -------------------------------------------------- 138
EPHA4           -------------------------------------------------- 138
EPHA3           -------------------------------------------------- 138
EPHA5           -------------------------------------------------- 138
PYK2            -------------------------------------------------- 137
CSK             -------------------------------------------------- 132
CTK             -------------------------------------------------- 130
1IEPA           -------------------------------------------------- 134
ABL             -------------------------------------------------- 134
ARG             -------------------------------------------------- 134
BRK             -------------------------------------------------- 134
SRM             -------------------------------------------------- 133
FRK             -------------------------------------------------- 133
FGR             -------------------------------------------------- 132
FYN             -------------------------------------------------- 132
SRC             -------------------------------------------------- 132
YES             -------------------------------------------------- 132
HCK             -------------------------------------------------- 132
LYN             -------------------------------------------------- 133
3LCK            -------------------------------------------------- 132
LCK             -------------------------------------------------- 132
BLK             -------------------------------------------------- 132
FER             -------------------------------------------------- 134
FES             -------------------------------------------------- 135
SYK             -------------------------------------------------- 136
ZAP70           -------------------------------------------------- 136
FGFR1           -------------------------------------------------- 158
FGFR2           -------------------------------------------------- 158
FGFR3           -------------------------------------------------- 158
FGFR4           -------------------------------------------------- 158
RET             -------------------------------------------------- 163
TIE1            -------------------------------------------------- 153
1FVRA           -------------------------------------------------- 153
TIE2            -------------------------------------------------- 153
FLT1            -------------------------------------------------- 208
KDR             -------------------------------------------------- 207
KDR_AVE         -------------------------------------------------- 150
FLT4            -------------------------------------------------- 205
FMS             -------------------------------------------------- 209
FLT3            -------------------------------------------------- 214
KIT             -------------------------------------------------- 216
PDGFRA          -------------------------------------------------- 238
PDGFRB          -------------------------------------------------- 239
MER             -------------------------------------------------- 149
AXL             -------------------------------------------------- 149
TYRO3           -------------------------------------------------- 150
MET             -------------------------------------------------- 139
RON             -------------------------------------------------- 139
HH498           -------------------------------------------------- 138
LZK             -------------------------------------------------- 124
DLK             -------------------------------------------------- 124
MLK1            -------------------------------------------------- 145
MLK3            -------------------------------------------------- 145
MLK2            -------------------------------------------------- 145
MLK4            -------------------------------------------------- 160
ZAK             -------------------------------------------------- 130
TAK1            -------------------------------------------------- 134
KSR1            -------------------------------------------------- 132
KSR2            -------------------------------------------------- 132
ARAF            -------------------------------------------------- 132
RAF1            -------------------------------------------------- 132
BRAF            -------------------------------------------------- 132
LRRK2           -------------------------------------------------- 133
ANKRD3          -------------------------------------------------- 134
SGK288          -------------------------------------------------- 133
RIPK2           -------------------------------------------------- 141
RIPK3           -------------------------------------------------- 134
MLKL            -------------------------------------------------- 136
ANPA            -------------------------------------------------- 138
ANPB            -------------------------------------------------- 138
CYGD            -------------------------------------------------- 146
CYGF            -------------------------------------------------- 151
TBCK            -------------------------------------------------- 111
ERK1            -------------------------------------------------- 137
3ERK            -------------------------------------------------- 137
ERK2            -------------------------------------------------- 137
ERK5            -------------------------------------------------- 140
1JNK            -------------------------------------------------- 138
1PMNA           -------------------------------------------------- 138
JNK3            -------------------------------------------------- 138
JNK1            -------------------------------------------------- 138
JNK2            -------------------------------------------------- 138
1P38            -------------------------------------------------- 139
P38A            -------------------------------------------------- 139
P38B            -------------------------------------------------- 147
P38D            -------------------------------------------------- 138
P38G            -------------------------------------------------- 139
NLK             -------------------------------------------------- 139
ERK7            -------------------------------------------------- 156
ERK3            -------------------------------------------------- 146
ERK4            -------------------------------------------------- 143
ICK             -------------------------------------------------- 134
MAK             -------------------------------------------------- 134
PCTAIRE1        -------------------------------------------------- 134
PCTAIRE2        -------------------------------------------------- 134
PCTAIRE3        -------------------------------------------------- 134
PFTAIRE1        -------------------------------------------------- 134
PFTAIRE2        -------------------------------------------------- 134
CDC2            -------------------------------------------------- 137
1HCL            -------------------------------------------------- 132
CDK2            -------------------------------------------------- 136
CDK3            -------------------------------------------------- 136
CDK5            -------------------------------------------------- 135
CDK7            -------------------------------------------------- 138
CDK4            -------------------------------------------------- 147
1BLXA           -------------------------------------------------- 145
CDK6            -------------------------------------------------- 145
PITSLRE         -------------------------------------------------- 137
CDK10           -------------------------------------------------- 137
CDK9            -------------------------------------------------- 143
CHED            -------------------------------------------------- 145
CRK7            -------------------------------------------------- 145
CCRK            -------------------------------------------------- 136
CDK11           -------------------------------------------------- 148
CDK8            -------------------------------------------------- 148
IKKA            -------------------------------------------------- 145
IKKB            -------------------------------------------------- 146
1PHK            -------------------------------------------------- 143
PHKG1           -------------------------------------------------- 143
PHKG2           -------------------------------------------------- 142
CAMK2A          -------------------------------------------------- 138
CAMK2B          -------------------------------------------------- 138
CAMK2G          -------------------------------------------------- 138
CAMK2D          -------------------------------------------------- 138
CASK            -------------------------------------------------- 145
1IA8A           -------------------------------------------------- 132
CHK1            -------------------------------------------------- 135
CLK1            -------------------------------------------------- 159
CLK4            -------------------------------------------------- 158
CLK2            -------------------------------------------------- 159
CLK3            -------------------------------------------------- 159
MAP2K5          -------------------------------------------------- 130
MAP2K3          -------------------------------------------------- 139
MAP2K6          -------------------------------------------------- 139
MAP2K4          -------------------------------------------------- 140
MAP2K7          -------------------------------------------------- 136
MAP2K1          -------------------------------------------------- 135
MAP2K2          -------------------------------------------------- 135
CDKL5           -------------------------------------------------- 135
CDKL1           -------------------------------------------------- 135
CDKL4           -------------------------------------------------- 135
CDKL2           -------------------------------------------------- 135
CDKL3           -------------------------------------------------- 134
1I09B           -------------------------------------------------- 139
GSK3B           -------------------------------------------------- 139
1J1BA           -------------------------------------------------- 139
GSK3A           -------------------------------------------------- 139
LATS1           -------------------------------------------------- 136
LATS2           -------------------------------------------------- 136
NDR1            -------------------------------------------------- 136
NDR2            -------------------------------------------------- 136
MAST1           -------------------------------------------------- 136
MAST4           -------------------------------------------------- 136
MAST2           -------------------------------------------------- 136
MAST3           -------------------------------------------------- 136
MRCKA           -------------------------------------------------- 137
MRCKB           -------------------------------------------------- 137
DMPK2           -------------------------------------------------- 137
DMPK1           -------------------------------------------------- 137
ROCK1           -------------------------------------------------- 135
ROCK2           -------------------------------------------------- 135
CRIK            -------------------------------------------------- 137
MASTL           -------------------------------------------------- 134
1O6LA           -------------------------------------------------- 136
AKT2            -------------------------------------------------- 136
AKT1            -------------------------------------------------- 137
AKT3            -------------------------------------------------- 136
MSK1            -------------------------------------------------- 141
MSK2            -------------------------------------------------- 141
P70S6K          -------------------------------------------------- 140
P70S6KB         -------------------------------------------------- 140
RSK1            -------------------------------------------------- 138
RSK3            -------------------------------------------------- 138
RSK2            -------------------------------------------------- 138
RSK4            -------------------------------------------------- 138
1FOTA           -------------------------------------------------- 136
1CDKA           -------------------------------------------------- 136
PKACA           -------------------------------------------------- 136
PKACB           -------------------------------------------------- 136
PKACG           -------------------------------------------------- 136
PRKX            -------------------------------------------------- 136
PRKY            -------------------------------------------------- 136
PKCA            -------------------------------------------------- 137
PKCB            -------------------------------------------------- 137
PKCG            -------------------------------------------------- 142
PKCE            -------------------------------------------------- 137
PKCH            -------------------------------------------------- 137
PKCD            -------------------------------------------------- 137
PKCT            -------------------------------------------------- 137
PKCI            -------------------------------------------------- 137
PKCZ            -------------------------------------------------- 137
PKN1            -------------------------------------------------- 138
PKN2            -------------------------------------------------- 138
PKN3            -------------------------------------------------- 138
SGK             -------------------------------------------------- 137
SGK2            -------------------------------------------------- 137
SGK3            -------------------------------------------------- 137
PKG1            -------------------------------------------------- 137
PKG2            -------------------------------------------------- 136
AURB            -------------------------------------------------- 136
AURC            -------------------------------------------------- 136
AURA            -------------------------------------------------- 136
AURORA2_AVE     -------------------------------------------------- 136
PLK1            -------------------------------------------------- 136
PLK2            -------------------------------------------------- 136
PLK3            -------------------------------------------------- 136
PLK4            -------------------------------------------------- 137
NEK11           -------------------------------------------------- 142
YANK1           -------------------------------------------------- 136
YANK2           -------------------------------------------------- 136
YANK3           -------------------------------------------------- 136
SGK494          -------------------------------------------------- 135
DOMAIN2_MSK1    -------------------------------------------------- 134
DOMAIN2_MSK2    -------------------------------------------------- 129
DOMAIN2_RSK1    -------------------------------------------------- 134
DOMAIN2_RSK2    -------------------------------------------------- 134
DOMAIN2_RSK3    -------------------------------------------------- 134
DOMAIN2_RSK4    -------------------------------------------------- 134
DRAK1           -------------------------------------------------- 141
DRAK2           -------------------------------------------------- 141
1JKSA           -------------------------------------------------- 143
DAPK1           -------------------------------------------------- 143
DAPK3           -------------------------------------------------- 143
DAPK2           -------------------------------------------------- 143
SGK085          -------------------------------------------------- 136
CAMLCK          -------------------------------------------------- 136
SKMLCK          -------------------------------------------------- 136
SMMLCK          -------------------------------------------------- 136
1KOBA           -------------------------------------------------- 136
1TKIA           -------------------------------------------------- 135
TTN             -------------------------------------------------- 135
PKD1            -------------------------------------------------- 139
PKD3            -------------------------------------------------- 139
PKD2            -------------------------------------------------- 139
PSKH1           -------------------------------------------------- 136
PSKH2           -------------------------------------------------- 136
CAMK1A          -------------------------------------------------- 137
CAMK1D          -------------------------------------------------- 137
CAMK1B          -------------------------------------------------- 137
CAMK1G          -------------------------------------------------- 136
CAMK4           -------------------------------------------------- 134
DCAMKL1         -------------------------------------------------- 138
DCAMKL2         -------------------------------------------------- 138
DCAMKL3         -------------------------------------------------- 138
CHK2            -------------------------------------------------- 143
MAPKAPK2        -------------------------------------------------- 138
MAPKAPK3        -------------------------------------------------- 138
MAPKAPK5        -------------------------------------------------- 142
MNK1            -------------------------------------------------- 138
MNK2            -------------------------------------------------- 137
VACAMKL         -------------------------------------------------- 137
GCK             -------------------------------------------------- 134
KHS1            -------------------------------------------------- 134
KHS2            -------------------------------------------------- 134
HPK1            -------------------------------------------------- 134
MST1            -------------------------------------------------- 133
MST2            -------------------------------------------------- 133
MST3            -------------------------------------------------- 134
YSK1            -------------------------------------------------- 134
MST4            -------------------------------------------------- 134
LOK             -------------------------------------------------- 135
SLK             -------------------------------------------------- 135
MAP3K4          -------------------------------------------------- 134
MAP3K2          -------------------------------------------------- 141
MAP3K3          -------------------------------------------------- 141
MAP3K8          -------------------------------------------------- 139
MAP3K5          -------------------------------------------------- 143
MAP3K7          -------------------------------------------------- 134
MAP3K6          -------------------------------------------------- 133
PAK1            -------------------------------------------------- 133
PAK3            -------------------------------------------------- 133
PAK2            -------------------------------------------------- 134
PAK4            -------------------------------------------------- 133
PAK5            -------------------------------------------------- 133
PAK6            -------------------------------------------------- 133
OSR1            -------------------------------------------------- 143
STLK3           -------------------------------------------------- 143
TAO1            -------------------------------------------------- 137
TAO3            -------------------------------------------------- 137
TAO2            -------------------------------------------------- 137
MYO3A           -------------------------------------------------- 143
MYO3B           -------------------------------------------------- 143
ZC1/HGK         -------------------------------------------------- 142
ZC3/MINK        -------------------------------------------------- 142
ZC2/TNIK        -------------------------------------------------- 142
ZC4/NRK         -------------------------------------------------- 166
MAP3K1          -------------------------------------------------- 140
GAK             -------------------------------------------------- 147
SGK495          -------------------------------------------------- 53
TRB1            -------------------------------------------------- 121
TRB2            -------------------------------------------------- 126
TRB3            -------------------------------------------------- 124
SSTK            -------------------------------------------------- 138
TSSK3           -------------------------------------------------- 137
TSSK1           -------------------------------------------------- 138
TSSK2           -------------------------------------------------- 138
TSSK4           -------------------------------------------------- 137
HUNK            -------------------------------------------------- 139
SNRK            -------------------------------------------------- 138
NIM1            -------------------------------------------------- 136
MELK            -------------------------------------------------- 135
BRSK1           -------------------------------------------------- 136
BRSK2           -------------------------------------------------- 136
MARK1           -------------------------------------------------- 136
MARK2           -------------------------------------------------- 136
MARK3           -------------------------------------------------- 136
MARK4           -------------------------------------------------- 136
QIK             -------------------------------------------------- 136
SIK             -------------------------------------------------- 136
QSK             -------------------------------------------------- 136
AMPKA1          -------------------------------------------------- 137
AMPKA2          -------------------------------------------------- 137
NUAK1           -------------------------------------------------- 137
NUAK2           -------------------------------------------------- 136
BIKE            -------------------------------------------------- 143
AAK1            -------------------------------------------------- 144
LIMK1           -------------------------------------------------- 135
LIMK2           -------------------------------------------------- 134
TESK1           -------------------------------------------------- 135
TESK2           -------------------------------------------------- 115
WNK1            -------------------------------------------------- 143
WNK3            -------------------------------------------------- 143
WNK2            -------------------------------------------------- 143
WNK4            -------------------------------------------------- 143
NEK10           -------------------------------------------------- 150
NEK6            -------------------------------------------------- 141
NEK7            -------------------------------------------------- 141
NEK2            -------------------------------------------------- 147
NEK1            -------------------------------------------------- 138
NEK5            -------------------------------------------------- 138
NEK3            -------------------------------------------------- 137
NEK4            -------------------------------------------------- 139
NEK8            -------------------------------------------------- 139
NEK9            -------------------------------------------------- 138
NRBP1           -------------------------------------------------- 151
NRBP2           -------------------------------------------------- 151
CLIK1           -------------------------------------------------- 174
CLIK1L          -------------------------------------------------- 177
STK33           -------------------------------------------------- 144
DOMAIN2_GCN2    -------------------------------------------------- 159
SCYL1           -------------------------------------------------- 126
SCYL3           -------------------------------------------------- 113
DOMAIN2_JAK1    -------------------------------------------------- 146
DOMAIN2_TYK2    -------------------------------------------------- 160
DOMAIN2_JAK2    -------------------------------------------------- 144
DOMAIN2_JAK3    -------------------------------------------------- 140
ILK             -------------------------------------------------- 140
LRRK1           -------------------------------------------------- 159
PBK             -------------------------------------------------- 148
WEE1            -------------------------------------------------- 142
WEE1B           -------------------------------------------------- 145
SGK071          -------------------------------------------------- 143
PIK3R4          -------------------------------------------------- 136
MSSK1           -QAEDSGLRLDGGSG----------------------------------- 234
SRPK1           TIGQDQTL--------MERDTEGGAAEI-----------NCNGVIEVINY 286
SRPK2           GEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPF 312
RSKL1           -------------------------------------------------- 121
RSKL2           -------------------------------------------------- 273
SGK396          -------------------------------------------------- 135
VRK1            -------------------------------------------------- 155
VRK2            -------------------------------------------------- 152
VRK3            -------------------------------------------------- 100
BUB1            -------------------------------------------------- 149
BUBR1           -------------------------------------------------- 148
SGK196          -------------------------------------------------- 135
SGK493          -------------------------------------------------- 150
                                                                  

DYRK1A          -------------------------------------------------- 144
DYRK1B          -------------------------------------------------- 144
DYRK2           -------------------------------------------------- 142
DYRK3           -------------------------------------------------- 142
DYRK4           -------------------------------------------------- 142
HIPK1           -------------------------------------------------- 142
HIPK2           -------------------------------------------------- 142
HIPK3           -------------------------------------------------- 142
HIPK4           -------------------------------------------------- 142
PRP4            -------------------------------------------------- 142
MOK             -------------------------------------------------- 136
1A6O            -------------------------------------------------- 131
1LPUA           -------------------------------------------------- 131
CK2A1           -------------------------------------------------- 131
CK2A1-RS        -------------------------------------------------- 131
CK2A2           -------------------------------------------------- 131
HSER            -------------------------------------------------- 138
SLOB            -------------------------------------------------- 157
CDC7            -------------------------------------------------- 133
1CSN            -------------------------------------------------- 137
CK1G1           -------------------------------------------------- 138
CK1G3           -------------------------------------------------- 137
CK1G2           -------------------------------------------------- 137
CK1A            -------------------------------------------------- 135
CK1A2           -------------------------------------------------- 135
1CKJA           -------------------------------------------------- 135
CK1D            -------------------------------------------------- 135
CK1E            -------------------------------------------------- 135
TTBK1           -------------------------------------------------- 137
TTBK2           -------------------------------------------------- 137
TLK1            -------------------------------------------------- 146
TLK2            -------------------------------------------------- 146
GPRK4           -------------------------------------------------- 138
GPRK6           -------------------------------------------------- 138
GPRK5           -------------------------------------------------- 138
RHOK            -------------------------------------------------- 140
GPRK7           -------------------------------------------------- 138
BARK1           -------------------------------------------------- 139
BARK2           -------------------------------------------------- 139
TTK             -------------------------------------------------- 134
RIPK1           -------------------------------------------------- 134
HASPIN          -------------------------------------------------- 198
GCN2            -------------------------------------------------- 271
HRI             -------------------------------------------------- 289
KIS             -------------------------------------------------- 149
PDK1            -------------------------------------------------- 136
PKR             -------------------------------------------------- 160
PEK             -------------------------------------------------- 357
PRPK            -------------------------------------------------- 145
DOMAIN2_OBSCN   -------------------------------------------------- 132
DOMAIN2_SPEG    -------------------------------------------------- 132
LMR1            -------------------------------------------------- 141
LMR2            -------------------------------------------------- 141
LMR3            -------------------------------------------------- 146
SGK307          -------------------------------------------------- 49
STLK5           -------------------------------------------------- 139
STLK6           -------------------------------------------------- 139
STLK6-RS        -------------------------------------------------- 139
OBSCN           -------------------------------------------------- 134
SPEG            -------------------------------------------------- 135
TRAD            -------------------------------------------------- 135
TRIO            -------------------------------------------------- 135
SGK223          -------------------------------------------------- 140
SGK269          -------------------------------------------------- 141
ALK1            -------------------------------------------------- 141
ALK2            -------------------------------------------------- 141
IRAK4           -------------------------------------------------- 138
BMPR2           -------------------------------------------------- 143
TGFBR2          -------------------------------------------------- 148
ACTR2           -------------------------------------------------- 143
ACTR2B          -------------------------------------------------- 144
1B6CB           -------------------------------------------------- 141
TGFBR1          -------------------------------------------------- 141
ALK4            -------------------------------------------------- 141
ALK7            -------------------------------------------------- 141
BMPR1A          -------------------------------------------------- 141
BMPR1B          -------------------------------------------------- 141
IRAK1           -------------------------------------------------- 141
IRAK2           -------------------------------------------------- 138
IRAK3           -------------------------------------------------- 141
MISR2           -------------------------------------------------- 143
MYT1            -------------------------------------------------- 136
SBK             -------------------------------------------------- 136
SGK110          -------------------------------------------------- 135
SGK069          -------------------------------------------------- 136
SGK496          -------------------------------------------------- 138
NIK             -------------------------------------------------- 129
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 150
IKKE            -------------------------------------------------- 143
TBK1            -------------------------------------------------- 143
MOS             -------------------------------------------------- 154
LKB1            -------------------------------------------------- 140
CAMKK1          -------------------------------------------------- 168
CAMKK2          -------------------------------------------------- 160
PASK            -------------------------------------------------- 142
PIM1            -------------------------------------------------- 143
PIM3            -------------------------------------------------- 144
PIM2            -------------------------------------------------- 145
COT             -------------------------------------------------- 130
SCYL2           -------------------------------------------------- 159
FUSED           -------------------------------------------------- 134
ULK1            -------------------------------------------------- 144
ULK2            -------------------------------------------------- 144
ULK3            -------------------------------------------------- 138
ULK4            -------------------------------------------------- 115
IRE1            -------------------------------------------------- 135
IRE2            -------------------------------------------------- 135
RNASEL          -------------------------------------------------- 129
MPSK1           -------------------------------------------------- 141
PINK1           -------------------------------------------------- 223
ALK             -------------------------------------------------- 149
LTK             -------------------------------------------------- 149
ROS             -------------------------------------------------- 152
IGF1R           -------------------------------------------------- 149
1IR3A           -------------------------------------------------- 149
INSR            -------------------------------------------------- 149
IRR             -------------------------------------------------- 149
1M14A           -------------------------------------------------- 138
EGFR            -------------------------------------------------- 138
HER2/ERBB2      -------------------------------------------------- 138
HER4/ERBB4      -------------------------------------------------- 138
HER3/ERBB3      -------------------------------------------------- 138
ITK             -------------------------------------------------- 132
TEC             -------------------------------------------------- 132
TXK             -------------------------------------------------- 132
BMX             -------------------------------------------------- 132
1K2PA           -------------------------------------------------- 132
BTK             -------------------------------------------------- 132
CCK4            -------------------------------------------------- 147
ROR1            -------------------------------------------------- 155
ROR2            -------------------------------------------------- 155
MUSK            -------------------------------------------------- 163
TRKA            -------------------------------------------------- 153
TRKB            -------------------------------------------------- 151
TRKC            -------------------------------------------------- 154
DDR1            -------------------------------------------------- 169
DDR2            -------------------------------------------------- 160
RYK             -------------------------------------------------- 148
JAK1            -------------------------------------------------- 140
JAK2            -------------------------------------------------- 140
JAK3            -------------------------------------------------- 140
ACK             -------------------------------------------------- 139
TYK2            -------------------------------------------------- 139
TNK1            -------------------------------------------------- 142
EPHA1           -------------------------------------------------- 138
EPHA10          -------------------------------------------------- 138
FAK             -------------------------------------------------- 137
EPHB6           -------------------------------------------------- 138
EPHA2           -------------------------------------------------- 139
EPHA8           -------------------------------------------------- 138
EPHA6           -------------------------------------------------- 180
EPHB1           -------------------------------------------------- 138
EPHB2           -------------------------------------------------- 138
EPHB3           -------------------------------------------------- 138
EPHB4           -------------------------------------------------- 138
EPHA7           -------------------------------------------------- 138
EPHA4           -------------------------------------------------- 138
EPHA3           -------------------------------------------------- 138
EPHA5           -------------------------------------------------- 138
PYK2            -------------------------------------------------- 137
CSK             -------------------------------------------------- 132
CTK             -------------------------------------------------- 130
1IEPA           -------------------------------------------------- 134
ABL             -------------------------------------------------- 134
ARG             -------------------------------------------------- 134
BRK             -------------------------------------------------- 134
SRM             -------------------------------------------------- 133
FRK             -------------------------------------------------- 133
FGR             -------------------------------------------------- 132
FYN             -------------------------------------------------- 132
SRC             -------------------------------------------------- 132
YES             -------------------------------------------------- 132
HCK             -------------------------------------------------- 132
LYN             -------------------------------------------------- 133
3LCK            -------------------------------------------------- 132
LCK             -------------------------------------------------- 132
BLK             -------------------------------------------------- 132
FER             -------------------------------------------------- 134
FES             -------------------------------------------------- 135
SYK             -------------------------------------------------- 136
ZAP70           -------------------------------------------------- 136
FGFR1           -------------------------------------------------- 158
FGFR2           -------------------------------------------------- 158
FGFR3           -------------------------------------------------- 158
FGFR4           -------------------------------------------------- 158
RET             -------------------------------------------------- 163
TIE1            -------------------------------------------------- 153
1FVRA           -------------------------------------------------- 153
TIE2            -------------------------------------------------- 153
FLT1            -------------------------------------------------- 208
KDR             -------------------------------------------------- 207
KDR_AVE         -------------------------------------------------- 150
FLT4            -------------------------------------------------- 205
FMS             -------------------------------------------------- 209
FLT3            -------------------------------------------------- 214
KIT             -------------------------------------------------- 216
PDGFRA          -------------------------------------------------- 238
PDGFRB          -------------------------------------------------- 239
MER             -------------------------------------------------- 149
AXL             -------------------------------------------------- 149
TYRO3           -------------------------------------------------- 150
MET             -------------------------------------------------- 139
RON             -------------------------------------------------- 139
HH498           -------------------------------------------------- 138
LZK             -------------------------------------------------- 124
DLK             -------------------------------------------------- 124
MLK1            -------------------------------------------------- 145
MLK3            -------------------------------------------------- 145
MLK2            -------------------------------------------------- 145
MLK4            -------------------------------------------------- 160
ZAK             -------------------------------------------------- 130
TAK1            -------------------------------------------------- 134
KSR1            -------------------------------------------------- 132
KSR2            -------------------------------------------------- 132
ARAF            -------------------------------------------------- 132
RAF1            -------------------------------------------------- 132
BRAF            -------------------------------------------------- 132
LRRK2           -------------------------------------------------- 133
ANKRD3          -------------------------------------------------- 134
SGK288          -------------------------------------------------- 133
RIPK2           -------------------------------------------------- 141
RIPK3           -------------------------------------------------- 134
MLKL            -------------------------------------------------- 136
ANPA            -------------------------------------------------- 138
ANPB            -------------------------------------------------- 138
CYGD            -------------------------------------------------- 146
CYGF            -------------------------------------------------- 151
TBCK            -------------------------------------------------- 111
ERK1            -------------------------------------------------- 137
3ERK            -------------------------------------------------- 137
ERK2            -------------------------------------------------- 137
ERK5            -------------------------------------------------- 140
1JNK            -------------------------------------------------- 138
1PMNA           -------------------------------------------------- 138
JNK3            -------------------------------------------------- 138
JNK1            -------------------------------------------------- 138
JNK2            -------------------------------------------------- 138
1P38            -------------------------------------------------- 139
P38A            -------------------------------------------------- 139
P38B            -------------------------------------------------- 147
P38D            -------------------------------------------------- 138
P38G            -------------------------------------------------- 139
NLK             -------------------------------------------------- 139
ERK7            -------------------------------------------------- 156
ERK3            -------------------------------------------------- 146
ERK4            -------------------------------------------------- 143
ICK             -------------------------------------------------- 134
MAK             -------------------------------------------------- 134
PCTAIRE1        -------------------------------------------------- 134
PCTAIRE2        -------------------------------------------------- 134
PCTAIRE3        -------------------------------------------------- 134
PFTAIRE1        -------------------------------------------------- 134
PFTAIRE2        -------------------------------------------------- 134
CDC2            -------------------------------------------------- 137
1HCL            -------------------------------------------------- 132
CDK2            -------------------------------------------------- 136
CDK3            -------------------------------------------------- 136
CDK5            -------------------------------------------------- 135
CDK7            -------------------------------------------------- 138
CDK4            -------------------------------------------------- 147
1BLXA           -------------------------------------------------- 145
CDK6            -------------------------------------------------- 145
PITSLRE         -------------------------------------------------- 137
CDK10           -------------------------------------------------- 137
CDK9            -------------------------------------------------- 143
CHED            -------------------------------------------------- 145
CRK7            -------------------------------------------------- 145
CCRK            -------------------------------------------------- 136
CDK11           -------------------------------------------------- 148
CDK8            -------------------------------------------------- 148
IKKA            -------------------------------------------------- 145
IKKB            -------------------------------------------------- 146
1PHK            -------------------------------------------------- 143
PHKG1           -------------------------------------------------- 143
PHKG2           -------------------------------------------------- 142
CAMK2A          -------------------------------------------------- 138
CAMK2B          -------------------------------------------------- 138
CAMK2G          -------------------------------------------------- 138
CAMK2D          -------------------------------------------------- 138
CASK            -------------------------------------------------- 145
1IA8A           -------------------------------------------------- 132
CHK1            -------------------------------------------------- 135
CLK1            -------------------------------------------------- 159
CLK4            -------------------------------------------------- 158
CLK2            -------------------------------------------------- 159
CLK3            -------------------------------------------------- 159
MAP2K5          -------------------------------------------------- 130
MAP2K3          -------------------------------------------------- 139
MAP2K6          -------------------------------------------------- 139
MAP2K4          -------------------------------------------------- 140
MAP2K7          -------------------------------------------------- 136
MAP2K1          -------------------------------------------------- 135
MAP2K2          -------------------------------------------------- 135
CDKL5           -------------------------------------------------- 135
CDKL1           -------------------------------------------------- 135
CDKL4           -------------------------------------------------- 135
CDKL2           -------------------------------------------------- 135
CDKL3           -------------------------------------------------- 134
1I09B           -------------------------------------------------- 139
GSK3B           -------------------------------------------------- 139
1J1BA           -------------------------------------------------- 139
GSK3A           -------------------------------------------------- 139
LATS1           -------------------------------------------------- 136
LATS2           -------------------------------------------------- 136
NDR1            -------------------------------------------------- 136
NDR2            -------------------------------------------------- 136
MAST1           -------------------------------------------------- 136
MAST4           -------------------------------------------------- 136
MAST2           -------------------------------------------------- 136
MAST3           -------------------------------------------------- 136
MRCKA           -------------------------------------------------- 137
MRCKB           -------------------------------------------------- 137
DMPK2           -------------------------------------------------- 137
DMPK1           -------------------------------------------------- 137
ROCK1           -------------------------------------------------- 135
ROCK2           -------------------------------------------------- 135
CRIK            -------------------------------------------------- 137
MASTL           -------------------------------------------------- 134
1O6LA           -------------------------------------------------- 136
AKT2            -------------------------------------------------- 136
AKT1            -------------------------------------------------- 137
AKT3            -------------------------------------------------- 136
MSK1            -------------------------------------------------- 141
MSK2            -------------------------------------------------- 141
P70S6K          -------------------------------------------------- 140
P70S6KB         -------------------------------------------------- 140
RSK1            -------------------------------------------------- 138
RSK3            -------------------------------------------------- 138
RSK2            -------------------------------------------------- 138
RSK4            -------------------------------------------------- 138
1FOTA           -------------------------------------------------- 136
1CDKA           -------------------------------------------------- 136
PKACA           -------------------------------------------------- 136
PKACB           -------------------------------------------------- 136
PKACG           -------------------------------------------------- 136
PRKX            -------------------------------------------------- 136
PRKY            -------------------------------------------------- 136
PKCA            -------------------------------------------------- 137
PKCB            -------------------------------------------------- 137
PKCG            -------------------------------------------------- 142
PKCE            -------------------------------------------------- 137
PKCH            -------------------------------------------------- 137
PKCD            -------------------------------------------------- 137
PKCT            -------------------------------------------------- 137
PKCI            -------------------------------------------------- 137
PKCZ            -------------------------------------------------- 137
PKN1            -------------------------------------------------- 138
PKN2            -------------------------------------------------- 138
PKN3            -------------------------------------------------- 138
SGK             -------------------------------------------------- 137
SGK2            -------------------------------------------------- 137
SGK3            -------------------------------------------------- 137
PKG1            -------------------------------------------------- 137
PKG2            -------------------------------------------------- 136
AURB            -------------------------------------------------- 136
AURC            -------------------------------------------------- 136
AURA            -------------------------------------------------- 136
AURORA2_AVE     -------------------------------------------------- 136
PLK1            -------------------------------------------------- 136
PLK2            -------------------------------------------------- 136
PLK3            -------------------------------------------------- 136
PLK4            -------------------------------------------------- 137
NEK11           -------------------------------------------------- 142
YANK1           -------------------------------------------------- 136
YANK2           -------------------------------------------------- 136
YANK3           -------------------------------------------------- 136
SGK494          -------------------------------------------------- 135
DOMAIN2_MSK1    -------------------------------------------------- 134
DOMAIN2_MSK2    -------------------------------------------------- 129
DOMAIN2_RSK1    -------------------------------------------------- 134
DOMAIN2_RSK2    -------------------------------------------------- 134
DOMAIN2_RSK3    -------------------------------------------------- 134
DOMAIN2_RSK4    -------------------------------------------------- 134
DRAK1           -------------------------------------------------- 141
DRAK2           -------------------------------------------------- 141
1JKSA           -------------------------------------------------- 143
DAPK1           -------------------------------------------------- 143
DAPK3           -------------------------------------------------- 143
DAPK2           -------------------------------------------------- 143
SGK085          -------------------------------------------------- 136
CAMLCK          -------------------------------------------------- 136
SKMLCK          -------------------------------------------------- 136
SMMLCK          -------------------------------------------------- 136
1KOBA           -------------------------------------------------- 136
1TKIA           -------------------------------------------------- 135
TTN             -------------------------------------------------- 135
PKD1            -------------------------------------------------- 139
PKD3            -------------------------------------------------- 139
PKD2            -------------------------------------------------- 139
PSKH1           -------------------------------------------------- 136
PSKH2           -------------------------------------------------- 136
CAMK1A          -------------------------------------------------- 137
CAMK1D          -------------------------------------------------- 137
CAMK1B          -------------------------------------------------- 137
CAMK1G          -------------------------------------------------- 136
CAMK4           -------------------------------------------------- 134
DCAMKL1         -------------------------------------------------- 138
DCAMKL2         -------------------------------------------------- 138
DCAMKL3         -------------------------------------------------- 138
CHK2            -------------------------------------------------- 143
MAPKAPK2        -------------------------------------------------- 138
MAPKAPK3        -------------------------------------------------- 138
MAPKAPK5        -------------------------------------------------- 142
MNK1            -------------------------------------------------- 138
MNK2            -------------------------------------------------- 137
VACAMKL         -------------------------------------------------- 137
GCK             -------------------------------------------------- 134
KHS1            -------------------------------------------------- 134
KHS2            -------------------------------------------------- 134
HPK1            -------------------------------------------------- 134
MST1            -------------------------------------------------- 133
MST2            -------------------------------------------------- 133
MST3            -------------------------------------------------- 134
YSK1            -------------------------------------------------- 134
MST4            -------------------------------------------------- 134
LOK             -------------------------------------------------- 135
SLK             -------------------------------------------------- 135
MAP3K4          -------------------------------------------------- 134
MAP3K2          -------------------------------------------------- 141
MAP3K3          -------------------------------------------------- 141
MAP3K8          -------------------------------------------------- 139
MAP3K5          -------------------------------------------------- 143
MAP3K7          -------------------------------------------------- 134
MAP3K6          -------------------------------------------------- 133
PAK1            -------------------------------------------------- 133
PAK3            -------------------------------------------------- 133
PAK2            -------------------------------------------------- 134
PAK4            -------------------------------------------------- 133
PAK5            -------------------------------------------------- 133
PAK6            -------------------------------------------------- 133
OSR1            -------------------------------------------------- 143
STLK3           -------------------------------------------------- 143
TAO1            -------------------------------------------------- 137
TAO3            -------------------------------------------------- 137
TAO2            -------------------------------------------------- 137
MYO3A           -------------------------------------------------- 143
MYO3B           -------------------------------------------------- 143
ZC1/HGK         -------------------------------------------------- 142
ZC3/MINK        -------------------------------------------------- 142
ZC2/TNIK        -------------------------------------------------- 142
ZC4/NRK         -------------------------------------------------- 166
MAP3K1          -------------------------------------------------- 140
GAK             -------------------------------------------------- 147
SGK495          -------------------------------------------------- 53
TRB1            -------------------------------------------------- 121
TRB2            -------------------------------------------------- 126
TRB3            -------------------------------------------------- 124
SSTK            -------------------------------------------------- 138
TSSK3           -------------------------------------------------- 137
TSSK1           -------------------------------------------------- 138
TSSK2           -------------------------------------------------- 138
TSSK4           -------------------------------------------------- 137
HUNK            -------------------------------------------------- 139
SNRK            -------------------------------------------------- 138
NIM1            -------------------------------------------------- 136
MELK            -------------------------------------------------- 135
BRSK1           -------------------------------------------------- 136
BRSK2           -------------------------------------------------- 136
MARK1           -------------------------------------------------- 136
MARK2           -------------------------------------------------- 136
MARK3           -------------------------------------------------- 136
MARK4           -------------------------------------------------- 136
QIK             -------------------------------------------------- 136
SIK             -------------------------------------------------- 136
QSK             -------------------------------------------------- 136
AMPKA1          -------------------------------------------------- 137
AMPKA2          -------------------------------------------------- 137
NUAK1           -------------------------------------------------- 137
NUAK2           -------------------------------------------------- 136
BIKE            -------------------------------------------------- 143
AAK1            -------------------------------------------------- 144
LIMK1           -------------------------------------------------- 135
LIMK2           -------------------------------------------------- 134
TESK1           -------------------------------------------------- 135
TESK2           -------------------------------------------------- 115
WNK1            -------------------------------------------------- 143
WNK3            -------------------------------------------------- 143
WNK2            -------------------------------------------------- 143
WNK4            -------------------------------------------------- 143
NEK10           -------------------------------------------------- 150
NEK6            -------------------------------------------------- 141
NEK7            -------------------------------------------------- 141
NEK2            -------------------------------------------------- 147
NEK1            -------------------------------------------------- 138
NEK5            -------------------------------------------------- 138
NEK3            -------------------------------------------------- 137
NEK4            -------------------------------------------------- 139
NEK8            -------------------------------------------------- 139
NEK9            -------------------------------------------------- 138
NRBP1           -------------------------------------------------- 151
NRBP2           -------------------------------------------------- 151
CLIK1           -------------------------------------------------- 174
CLIK1L          -------------------------------------------------- 177
STK33           -------------------------------------------------- 144
DOMAIN2_GCN2    -------------------------------------------------- 159
SCYL1           -------------------------------------------------- 126
SCYL3           -------------------------------------------------- 113
DOMAIN2_JAK1    -------------------------------------------------- 146
DOMAIN2_TYK2    -------------------------------------------------- 160
DOMAIN2_JAK2    -------------------------------------------------- 144
DOMAIN2_JAK3    -------------------------------------------------- 140
ILK             -------------------------------------------------- 140
LRRK1           -------------------------------------------------- 159
PBK             -------------------------------------------------- 148
WEE1            -------------------------------------------------- 142
WEE1B           -------------------------------------------------- 145
SGK071          -------------------------------------------------- 143
PIK3R4          -------------------------------------------------- 136
MSSK1           -----------------------------------STSSSGFSGSL---- 245
SRPK1           T-QNSNNETLRHKEDLHNANDCDVQNLNQESSFL----------SLPNGD 325
SRPK2           SLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSSYEQFNGELPNGR 362
RSKL1           -------------------------------------------------- 121
RSKL2           -------------------------------------------------- 273
SGK396          -------------------------------------------------- 135
VRK1            -------------------------------------------------- 155
VRK2            -------------------------------------------------- 152
VRK3            -------------------------------------------------- 100
BUB1            -------------------------------------------------- 149
BUBR1           -------------------------------------------------- 148
SGK196          -------------------------------------------------- 135
SGK493          -------------------------------------------------- 150
                                                                  

DYRK1A          -------------------------------------------------- 144
DYRK1B          -------------------------------------------------- 144
DYRK2           -------------------------------------------------- 142
DYRK3           -------------------------------------------------- 142
DYRK4           -------------------------------------------------- 142
HIPK1           -------------------------------------------------- 142
HIPK2           -------------------------------------------------- 142
HIPK3           -------------------------------------------------- 142
HIPK4           -------------------------------------------------- 142
PRP4            -------------------------------------------------- 142
MOK             -------------------------------------------------- 136
1A6O            -------------------------------------------------- 131
1LPUA           -------------------------------------------------- 131
CK2A1           -------------------------------------------------- 131
CK2A1-RS        -------------------------------------------------- 131
CK2A2           -------------------------------------------------- 131
HSER            -------------------------------------------------- 138
SLOB            -------------------------------------------------- 157
CDC7            -------------------------------------------------- 133
1CSN            -------------------------------------------------- 137
CK1G1           -------------------------------------------------- 138
CK1G3           -------------------------------------------------- 137
CK1G2           -------------------------------------------------- 137
CK1A            -------------------------------------------------- 135
CK1A2           -------------------------------------------------- 135
1CKJA           -------------------------------------------------- 135
CK1D            -------------------------------------------------- 135
CK1E            -------------------------------------------------- 135
TTBK1           -------------------------------------------------- 137
TTBK2           -------------------------------------------------- 137
TLK1            -------------------------------------------------- 146
TLK2            -------------------------------------------------- 146
GPRK4           -------------------------------------------------- 138
GPRK6           -------------------------------------------------- 138
GPRK5           -------------------------------------------------- 138
RHOK            -------------------------------------------------- 140
GPRK7           -------------------------------------------------- 138
BARK1           -------------------------------------------------- 139
BARK2           -------------------------------------------------- 139
TTK             -------------------------------------------------- 134
RIPK1           -------------------------------------------------- 134
HASPIN          -------------------------------------------------- 198
GCN2            -------------------------------------------------- 271
HRI             -------------------------------------------------- 289
KIS             -------------------------------------------------- 149
PDK1            -------------------------------------------------- 136
PKR             -------------------------------------------------- 160
PEK             -------------------------------------------------- 357
PRPK            -------------------------------------------------- 145
DOMAIN2_OBSCN   -------------------------------------------------- 132
DOMAIN2_SPEG    -------------------------------------------------- 132
LMR1            -------------------------------------------------- 141
LMR2            -------------------------------------------------- 141
LMR3            -------------------------------------------------- 146
SGK307          -------------------------------------------------- 49
STLK5           -------------------------------------------------- 139
STLK6           -------------------------------------------------- 139
STLK6-RS        -------------------------------------------------- 139
OBSCN           -------------------------------------------------- 134
SPEG            -------------------------------------------------- 135
TRAD            -------------------------------------------------- 135
TRIO            -------------------------------------------------- 135
SGK223          -------------------------------------------------- 140
SGK269          -------------------------------------------------- 141
ALK1            -------------------------------------------------- 141
ALK2            -------------------------------------------------- 141
IRAK4           -------------------------------------------------- 138
BMPR2           -------------------------------------------------- 143
TGFBR2          -------------------------------------------------- 148
ACTR2           -------------------------------------------------- 143
ACTR2B          -------------------------------------------------- 144
1B6CB           -------------------------------------------------- 141
TGFBR1          -------------------------------------------------- 141
ALK4            -------------------------------------------------- 141
ALK7            -------------------------------------------------- 141
BMPR1A          -------------------------------------------------- 141
BMPR1B          -------------------------------------------------- 141
IRAK1           -------------------------------------------------- 141
IRAK2           -------------------------------------------------- 138
IRAK3           -------------------------------------------------- 141
MISR2           -------------------------------------------------- 143
MYT1            -------------------------------------------------- 136
SBK             -------------------------------------------------- 136
SGK110          -------------------------------------------------- 135
SGK069          -------------------------------------------------- 136
SGK496          -------------------------------------------------- 138
NIK             -------------------------------------------------- 129
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 150
IKKE            -------------------------------------------------- 143
TBK1            -------------------------------------------------- 143
MOS             -------------------------------------------------- 154
LKB1            -------------------------------------------------- 140
CAMKK1          -------------------------------------------------- 168
CAMKK2          -------------------------------------------------- 160
PASK            -------------------------------------------------- 142
PIM1            -------------------------------------------------- 143
PIM3            -------------------------------------------------- 144
PIM2            -------------------------------------------------- 145
COT             -------------------------------------------------- 130
SCYL2           -------------------------------------------------- 159
FUSED           -------------------------------------------------- 134
ULK1            -------------------------------------------------- 144
ULK2            -------------------------------------------------- 144
ULK3            -------------------------------------------------- 138
ULK4            -------------------------------------------------- 115
IRE1            -------------------------------------------------- 135
IRE2            -------------------------------------------------- 135
RNASEL          -------------------------------------------------- 129
MPSK1           -------------------------------------------------- 141
PINK1           -------------------------------------------------- 223
ALK             -------------------------------------------------- 149
LTK             -------------------------------------------------- 149
ROS             -------------------------------------------------- 152
IGF1R           -------------------------------------------------- 149
1IR3A           -------------------------------------------------- 149
INSR            -------------------------------------------------- 149
IRR             -------------------------------------------------- 149
1M14A           -------------------------------------------------- 138
EGFR            -------------------------------------------------- 138
HER2/ERBB2      -------------------------------------------------- 138
HER4/ERBB4      -------------------------------------------------- 138
HER3/ERBB3      -------------------------------------------------- 138
ITK             -------------------------------------------------- 132
TEC             -------------------------------------------------- 132
TXK             -------------------------------------------------- 132
BMX             -------------------------------------------------- 132
1K2PA           -------------------------------------------------- 132
BTK             -------------------------------------------------- 132
CCK4            -------------------------------------------------- 147
ROR1            -------------------------------------------------- 155
ROR2            -------------------------------------------------- 155
MUSK            -------------------------------------------------- 163
TRKA            -------------------------------------------------- 153
TRKB            -------------------------------------------------- 151
TRKC            -------------------------------------------------- 154
DDR1            -------------------------------------------------- 169
DDR2            -------------------------------------------------- 160
RYK             -------------------------------------------------- 148
JAK1            -------------------------------------------------- 140
JAK2            -------------------------------------------------- 140
JAK3            -------------------------------------------------- 140
ACK             -------------------------------------------------- 139
TYK2            -------------------------------------------------- 139
TNK1            -------------------------------------------------- 142
EPHA1           -------------------------------------------------- 138
EPHA10          -------------------------------------------------- 138
FAK             -------------------------------------------------- 137
EPHB6           -------------------------------------------------- 138
EPHA2           -------------------------------------------------- 139
EPHA8           -------------------------------------------------- 138
EPHA6           -------------------------------------------------- 180
EPHB1           -------------------------------------------------- 138
EPHB2           -------------------------------------------------- 138
EPHB3           -------------------------------------------------- 138
EPHB4           -------------------------------------------------- 138
EPHA7           -------------------------------------------------- 138
EPHA4           -------------------------------------------------- 138
EPHA3           -------------------------------------------------- 138
EPHA5           -------------------------------------------------- 138
PYK2            -------------------------------------------------- 137
CSK             -------------------------------------------------- 132
CTK             -------------------------------------------------- 130
1IEPA           -------------------------------------------------- 134
ABL             -------------------------------------------------- 134
ARG             -------------------------------------------------- 134
BRK             -------------------------------------------------- 134
SRM             -------------------------------------------------- 133
FRK             -------------------------------------------------- 133
FGR             -------------------------------------------------- 132
FYN             -------------------------------------------------- 132
SRC             -------------------------------------------------- 132
YES             -------------------------------------------------- 132
HCK             -------------------------------------------------- 132
LYN             -------------------------------------------------- 133
3LCK            -------------------------------------------------- 132
LCK             -------------------------------------------------- 132
BLK             -------------------------------------------------- 132
FER             -------------------------------------------------- 134
FES             -------------------------------------------------- 135
SYK             -------------------------------------------------- 136
ZAP70           -------------------------------------------------- 136
FGFR1           -------------------------------------------------- 158
FGFR2           -------------------------------------------------- 158
FGFR3           -------------------------------------------------- 158
FGFR4           -------------------------------------------------- 158
RET             -------------------------------------------------- 163
TIE1            -------------------------------------------------- 153
1FVRA           -------------------------------------------------- 153
TIE2            -------------------------------------------------- 153
FLT1            -------------------------------------------------- 208
KDR             -------------------------------------------------- 207
KDR_AVE         -------------------------------------------------- 150
FLT4            -------------------------------------------------- 205
FMS             -------------------------------------------------- 209
FLT3            -------------------------------------------------- 214
KIT             -------------------------------------------------- 216
PDGFRA          -------------------------------------------------- 238
PDGFRB          -------------------------------------------------- 239
MER             -------------------------------------------------- 149
AXL             -------------------------------------------------- 149
TYRO3           -------------------------------------------------- 150
MET             -------------------------------------------------- 139
RON             -------------------------------------------------- 139
HH498           -------------------------------------------------- 138
LZK             -------------------------------------------------- 124
DLK             -------------------------------------------------- 124
MLK1            -------------------------------------------------- 145
MLK3            -------------------------------------------------- 145
MLK2            -------------------------------------------------- 145
MLK4            -------------------------------------------------- 160
ZAK             -------------------------------------------------- 130
TAK1            -------------------------------------------------- 134
KSR1            -------------------------------------------------- 132
KSR2            -------------------------------------------------- 132
ARAF            -------------------------------------------------- 132
RAF1            -------------------------------------------------- 132
BRAF            -------------------------------------------------- 132
LRRK2           -------------------------------------------------- 133
ANKRD3          -------------------------------------------------- 134
SGK288          -------------------------------------------------- 133
RIPK2           -------------------------------------------------- 141
RIPK3           -------------------------------------------------- 134
MLKL            -------------------------------------------------- 136
ANPA            -------------------------------------------------- 138
ANPB            -------------------------------------------------- 138
CYGD            -------------------------------------------------- 146
CYGF            -------------------------------------------------- 151
TBCK            -------------------------------------------------- 111
ERK1            -------------------------------------------------- 137
3ERK            -------------------------------------------------- 137
ERK2            -------------------------------------------------- 137
ERK5            -------------------------------------------------- 140
1JNK            -------------------------------------------------- 138
1PMNA           -------------------------------------------------- 138
JNK3            -------------------------------------------------- 138
JNK1            -------------------------------------------------- 138
JNK2            -------------------------------------------------- 138
1P38            -------------------------------------------------- 139
P38A            -------------------------------------------------- 139
P38B            -------------------------------------------------- 147
P38D            -------------------------------------------------- 138
P38G            -------------------------------------------------- 139
NLK             -------------------------------------------------- 139
ERK7            -------------------------------------------------- 156
ERK3            -------------------------------------------------- 146
ERK4            -------------------------------------------------- 143
ICK             -------------------------------------------------- 134
MAK             -------------------------------------------------- 134
PCTAIRE1        -------------------------------------------------- 134
PCTAIRE2        -------------------------------------------------- 134
PCTAIRE3        -------------------------------------------------- 134
PFTAIRE1        -------------------------------------------------- 134
PFTAIRE2        -------------------------------------------------- 134
CDC2            -------------------------------------------------- 137
1HCL            -------------------------------------------------- 132
CDK2            -------------------------------------------------- 136
CDK3            -------------------------------------------------- 136
CDK5            -------------------------------------------------- 135
CDK7            -------------------------------------------------- 138
CDK4            -------------------------------------------------- 147
1BLXA           -------------------------------------------------- 145
CDK6            -------------------------------------------------- 145
PITSLRE         -------------------------------------------------- 137
CDK10           -------------------------------------------------- 137
CDK9            -------------------------------------------------- 143
CHED            -------------------------------------------------- 145
CRK7            -------------------------------------------------- 145
CCRK            -------------------------------------------------- 136
CDK11           -------------------------------------------------- 148
CDK8            -------------------------------------------------- 148
IKKA            -------------------------------------------------- 145
IKKB            -------------------------------------------------- 146
1PHK            -------------------------------------------------- 143
PHKG1           -------------------------------------------------- 143
PHKG2           -------------------------------------------------- 142
CAMK2A          -------------------------------------------------- 138
CAMK2B          -------------------------------------------------- 138
CAMK2G          -------------------------------------------------- 138
CAMK2D          -------------------------------------------------- 138
CASK            -------------------------------------------------- 145
1IA8A           -------------------------------------------------- 132
CHK1            -------------------------------------------------- 135
CLK1            -------------------------------------------------- 159
CLK4            -------------------------------------------------- 158
CLK2            -------------------------------------------------- 159
CLK3            -------------------------------------------------- 159
MAP2K5          -------------------------------------------------- 130
MAP2K3          -------------------------------------------------- 139
MAP2K6          -------------------------------------------------- 139
MAP2K4          -------------------------------------------------- 140
MAP2K7          -------------------------------------------------- 136
MAP2K1          -------------------------------------------------- 135
MAP2K2          -------------------------------------------------- 135
CDKL5           -------------------------------------------------- 135
CDKL1           -------------------------------------------------- 135
CDKL4           -------------------------------------------------- 135
CDKL2           -------------------------------------------------- 135
CDKL3           -------------------------------------------------- 134
1I09B           -------------------------------------------------- 139
GSK3B           -------------------------------------------------- 139
1J1BA           -------------------------------------------------- 139
GSK3A           -------------------------------------------------- 139
LATS1           -------------------------------------------------- 136
LATS2           -------------------------------------------------- 136
NDR1            -------------------------------------------------- 136
NDR2            -------------------------------------------------- 136
MAST1           -------------------------------------------------- 136
MAST4           -------------------------------------------------- 136
MAST2           -------------------------------------------------- 136
MAST3           -------------------------------------------------- 136
MRCKA           -------------------------------------------------- 137
MRCKB           -------------------------------------------------- 137
DMPK2           -------------------------------------------------- 137
DMPK1           -------------------------------------------------- 137
ROCK1           -------------------------------------------------- 135
ROCK2           -------------------------------------------------- 135
CRIK            -------------------------------------------------- 137
MASTL           -------------------------------------------------- 134
1O6LA           -------------------------------------------------- 136
AKT2            -------------------------------------------------- 136
AKT1            -------------------------------------------------- 137
AKT3            -------------------------------------------------- 136
MSK1            -------------------------------------------------- 141
MSK2            -------------------------------------------------- 141
P70S6K          -------------------------------------------------- 140
P70S6KB         -------------------------------------------------- 140
RSK1            -------------------------------------------------- 138
RSK3            -------------------------------------------------- 138
RSK2            -------------------------------------------------- 138
RSK4            -------------------------------------------------- 138
1FOTA           -------------------------------------------------- 136
1CDKA           -------------------------------------------------- 136
PKACA           -------------------------------------------------- 136
PKACB           -------------------------------------------------- 136
PKACG           -------------------------------------------------- 136
PRKX            -------------------------------------------------- 136
PRKY            -------------------------------------------------- 136
PKCA            -------------------------------------------------- 137
PKCB            -------------------------------------------------- 137
PKCG            -------------------------------------------------- 142
PKCE            -------------------------------------------------- 137
PKCH            -------------------------------------------------- 137
PKCD            -------------------------------------------------- 137
PKCT            -------------------------------------------------- 137
PKCI            -------------------------------------------------- 137
PKCZ            -------------------------------------------------- 137
PKN1            -------------------------------------------------- 138
PKN2            -------------------------------------------------- 138
PKN3            -------------------------------------------------- 138
SGK             -------------------------------------------------- 137
SGK2            -------------------------------------------------- 137
SGK3            -------------------------------------------------- 137
PKG1            -------------------------------------------------- 137
PKG2            -------------------------------------------------- 136
AURB            -------------------------------------------------- 136
AURC            -------------------------------------------------- 136
AURA            -------------------------------------------------- 136
AURORA2_AVE     -------------------------------------------------- 136
PLK1            -------------------------------------------------- 136
PLK2            -------------------------------------------------- 136
PLK3            -------------------------------------------------- 136
PLK4            -------------------------------------------------- 137
NEK11           -------------------------------------------------- 142
YANK1           -------------------------------------------------- 136
YANK2           -------------------------------------------------- 136
YANK3           -------------------------------------------------- 136
SGK494          -------------------------------------------------- 135
DOMAIN2_MSK1    -------------------------------------------------- 134
DOMAIN2_MSK2    -------------------------------------------------- 129
DOMAIN2_RSK1    -------------------------------------------------- 134
DOMAIN2_RSK2    -------------------------------------------------- 134
DOMAIN2_RSK3    -------------------------------------------------- 134
DOMAIN2_RSK4    -------------------------------------------------- 134
DRAK1           -------------------------------------------------- 141
DRAK2           -------------------------------------------------- 141
1JKSA           -------------------------------------------------- 143
DAPK1           -------------------------------------------------- 143
DAPK3           -------------------------------------------------- 143
DAPK2           -------------------------------------------------- 143
SGK085          -------------------------------------------------- 136
CAMLCK          -------------------------------------------------- 136
SKMLCK          -------------------------------------------------- 136
SMMLCK          -------------------------------------------------- 136
1KOBA           -------------------------------------------------- 136
1TKIA           -------------------------------------------------- 135
TTN             -------------------------------------------------- 135
PKD1            -------------------------------------------------- 139
PKD3            -------------------------------------------------- 139
PKD2            -------------------------------------------------- 139
PSKH1           -------------------------------------------------- 136
PSKH2           -------------------------------------------------- 136
CAMK1A          -------------------------------------------------- 137
CAMK1D          -------------------------------------------------- 137
CAMK1B          -------------------------------------------------- 137
CAMK1G          -------------------------------------------------- 136
CAMK4           -------------------------------------------------- 134
DCAMKL1         -------------------------------------------------- 138
DCAMKL2         -------------------------------------------------- 138
DCAMKL3         -------------------------------------------------- 138
CHK2            -------------------------------------------------- 143
MAPKAPK2        -------------------------------------------------- 138
MAPKAPK3        -------------------------------------------------- 138
MAPKAPK5        -------------------------------------------------- 142
MNK1            -------------------------------------------------- 138
MNK2            -------------------------------------------------- 137
VACAMKL         -------------------------------------------------- 137
GCK             -------------------------------------------------- 134
KHS1            -------------------------------------------------- 134
KHS2            -------------------------------------------------- 134
HPK1            -------------------------------------------------- 134
MST1            -------------------------------------------------- 133
MST2            -------------------------------------------------- 133
MST3            -------------------------------------------------- 134
YSK1            -------------------------------------------------- 134
MST4            -------------------------------------------------- 134
LOK             -------------------------------------------------- 135
SLK             -------------------------------------------------- 135
MAP3K4          -------------------------------------------------- 134
MAP3K2          -------------------------------------------------- 141
MAP3K3          -------------------------------------------------- 141
MAP3K8          -------------------------------------------------- 139
MAP3K5          -------------------------------------------------- 143
MAP3K7          -------------------------------------------------- 134
MAP3K6          -------------------------------------------------- 133
PAK1            -------------------------------------------------- 133
PAK3            -------------------------------------------------- 133
PAK2            -------------------------------------------------- 134
PAK4            -------------------------------------------------- 133
PAK5            -------------------------------------------------- 133
PAK6            -------------------------------------------------- 133
OSR1            -------------------------------------------------- 143
STLK3           -------------------------------------------------- 143
TAO1            -------------------------------------------------- 137
TAO3            -------------------------------------------------- 137
TAO2            -------------------------------------------------- 137
MYO3A           -------------------------------------------------- 143
MYO3B           -------------------------------------------------- 143
ZC1/HGK         -------------------------------------------------- 142
ZC3/MINK        -------------------------------------------------- 142
ZC2/TNIK        -------------------------------------------------- 142
ZC4/NRK         -------------------------------------------------- 166
MAP3K1          -------------------------------------------------- 140
GAK             -------------------------------------------------- 147
SGK495          -------------------------------------------------- 53
TRB1            -------------------------------------------------- 121
TRB2            -------------------------------------------------- 126
TRB3            -------------------------------------------------- 124
SSTK            -------------------------------------------------- 138
TSSK3           -------------------------------------------------- 137
TSSK1           -------------------------------------------------- 138
TSSK2           -------------------------------------------------- 138
TSSK4           -------------------------------------------------- 137
HUNK            -------------------------------------------------- 139
SNRK            -------------------------------------------------- 138
NIM1            -------------------------------------------------- 136
MELK            -------------------------------------------------- 135
BRSK1           -------------------------------------------------- 136
BRSK2           -------------------------------------------------- 136
MARK1           -------------------------------------------------- 136
MARK2           -------------------------------------------------- 136
MARK3           -------------------------------------------------- 136
MARK4           -------------------------------------------------- 136
QIK             -------------------------------------------------- 136
SIK             -------------------------------------------------- 136
QSK             -------------------------------------------------- 136
AMPKA1          -------------------------------------------------- 137
AMPKA2          -------------------------------------------------- 137
NUAK1           -------------------------------------------------- 137
NUAK2           -------------------------------------------------- 136
BIKE            -------------------------------------------------- 143
AAK1            -------------------------------------------------- 144
LIMK1           -------------------------------------------------- 135
LIMK2           -------------------------------------------------- 134
TESK1           -------------------------------------------------- 135
TESK2           -------------------------------------------------- 115
WNK1            -------------------------------------------------- 143
WNK3            -------------------------------------------------- 143
WNK2            -------------------------------------------------- 143
WNK4            -------------------------------------------------- 143
NEK10           -------------------------------------------------- 150
NEK6            -------------------------------------------------- 141
NEK7            -------------------------------------------------- 141
NEK2            -------------------------------------------------- 147
NEK1            -------------------------------------------------- 138
NEK5            -------------------------------------------------- 138
NEK3            -------------------------------------------------- 137
NEK4            -------------------------------------------------- 139
NEK8            -------------------------------------------------- 139
NEK9            -------------------------------------------------- 138
NRBP1           -------------------------------------------------- 151
NRBP2           -------------------------------------------------- 151
CLIK1           -------------------------------------------------- 174
CLIK1L          -------------------------------------------------- 177
STK33           -------------------------------------------------- 144
DOMAIN2_GCN2    -------------------------------------------------- 159
SCYL1           -------------------------------------------------- 126
SCYL3           -------------------------------------------------- 113
DOMAIN2_JAK1    -------------------------------------------------- 146
DOMAIN2_TYK2    -------------------------------------------------- 160
DOMAIN2_JAK2    -------------------------------------------------- 144
DOMAIN2_JAK3    -------------------------------------------------- 140
ILK             -------------------------------------------------- 140
LRRK1           -------------------------------------------------- 159
PBK             -------------------------------------------------- 148
WEE1            -------------------------------------------------- 142
WEE1B           -------------------------------------------------- 145
SGK071          -------------------------------------------------- 143
PIK3R4          -------------------------------------------------- 136
MSSK1           -------FSPASCSILSGSSNQRETGGLL--------------------- 267
SRPK1           SST--SQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIRAE 373
SRPK2           HKIPESQFPEFSTSLFSGSLEPVACGSVLSEGSPLTEQEESSPSHDRSRT 412
RSKL1           -------------------------------------------------- 121
RSKL2           -------------------------------------------------- 273
SGK396          -------------------------------------------------- 135
VRK1            -------------------------------------------------- 155
VRK2            -------------------------------------------------- 152
VRK3            -------------------------------------------------- 100
BUB1            -------------------------------------------------- 149
BUBR1           -------------------------------------------------- 148
SGK196          -------------------------------------------------- 135
SGK493          -------------------------------------------------- 150
                                                                  

DYRK1A          ----------------------------------------IKIVD-FGSS 153
DYRK1B          ----------------------------------------IKIVD-FGSS 153
DYRK2           ----------------------------------------IKVID-FGSS 151
DYRK3           ----------------------------------------TKVID-FGSS 151
DYRK4           ----------------------------------------VKVID-FGSS 151
HIPK1           ---------------------------------------RVKVID-FGSA 152
HIPK2           ---------------------------------------RVKVID-FGSA 152
HIPK3           ---------------------------------------RVKVID-FGSA 152
HIPK4           ---------------------------------------RVKVID-FGSA 152
PRP4            ---------------------------------------ILKLCD-FGSA 152
MOK             ---------------------------------------VLKLGD-FGSC 146
1A6O            ---------------------------------------KLRLID-WGLA 141
1LPUA           ---------------------------------------KLRLID-WGLA 141
CK2A1           ---------------------------------------KLRLID-WGLA 141
CK2A1-RS        ---------------------------------------KLRLID-WGLA 141
CK2A2           ---------------------------------------KLRLID-WGLA 141
HSER            ---------------------------------------VVKITD-FGCN 148
SLOB            ----------------------------------------LENSL-LGLP 166
CDC7            ---------------------------------------KYALVD-FGLA 143
1CSN            ---------------------------------------MIYVVD-FGMV 147
CK1G1           ---------------------------------------VIHIID-FGLA 148
CK1G3           ---------------------------------------VIHIID-FGLA 147
CK1G2           ---------------------------------------AIHIID-FGLA 147
CK1A            ---------------------------------------KLFLID-FGLA 145
CK1A2           ---------------------------------------KLFLID-FGLA 145
1CKJA           ---------------------------------------LVYIID-FGLA 145
CK1D            ---------------------------------------LVYIID-FGLA 145
CK1E            ---------------------------------------LVYIID-FGLA 145
TTBK1           ---------------------------------------KCYMLD-FGLA 147
TTBK2           ---------------------------------------KCYMLD-FGLA 147
TLK1            ---------------------------------------EIKITD-FGLS 156
TLK2            ---------------------------------------EIKITD-FGLS 156
GPRK4           ---------------------------------------HIRISD-LGLA 148
GPRK6           ---------------------------------------HIRISD-LGLA 148
GPRK5           ---------------------------------------HIRISD-LGLA 148
RHOK            ---------------------------------------NVRISD-LGLA 150
GPRK7           ---------------------------------------NCRLSD-LGLA 148
BARK1           ---------------------------------------HVRISD-LGLA 149
BARK2           ---------------------------------------HARISD-LGLA 149
TTK             ---------------------------------------MLKLID-FGIA 144
RIPK1           ---------------------------------------HIKIAD-LGLA 144
HASPIN          ---------------------------------------QVSIID-YTLS 208
GCN2            ---------------------------------------HVKIGD-FGLA 281
HRI             ---------------------------------------QVKIGD-FGLA 299
KIS             ---------------------------------------CFKLID-FGLS 159
PDK1            ---------------------------------------HIQITD-FGTA 146
PKR             ---------------------------------------QVKIGD-FGLV 170
PEK             ---------------------------------------VVKVGD-FGLV 367
PRPK            ---------------------------------------NIVLID-FGLS 155
DOMAIN2_OBSCN   ---------------------------------------LLKVVD-L--- 139
DOMAIN2_SPEG    ---------------------------------------ALKIVD-F--- 139
LMR1            ---------------------------------------TVKIGD-Y--- 148
LMR2            ---------------------------------------NVKVGD-Y--- 148
LMR3            ---------------------------------------TVRIGD-Y--- 153
SGK307          ---------------------------------------EARLTN-LEY- 58
STLK5           ---------------------------------------KVYLSG-L--- 146
STLK6           ---------------------------------------LVTLSG-L--- 146
STLK6-RS        ---------------------------------------LVTLSG-L--- 146
OBSCN           ---------------------------------------DIKICD-F--- 141
SPEG            ---------------------------------------QVRICD-F--- 142
TRAD            ---------------------------------------RVKLID-L--- 142
TRIO            ---------------------------------------TIKLAD-F--- 142
SGK223          ---------------------------------------LQAGPG-PAPA 150
SGK269          -------------------------------------------------- 141
ALK1            ---------------------------------------QCCIAD-LGLA 151
ALK2            ---------------------------------------QCCIAD-LGLA 151
IRAK4           ---------------------------------------TAKISD-FGLA 148
BMPR2           ---------------------------------------TCVISD-FGLS 153
TGFBR2          ---------------------------------------TCCLCD-FGLS 158
ACTR2           ---------------------------------------TACIAD-FGLA 153
ACTR2B          ---------------------------------------TAVLAD-FGLA 154
1B6CB           ---------------------------------------TCCIAD-LGLA 151
TGFBR1          ---------------------------------------TCCIAD-LGLA 151
ALK4            ---------------------------------------MCAIAD-LGLA 151
ALK7            ---------------------------------------TCAIAD-LGLA 151
BMPR1A          ---------------------------------------SCCIAD-LGLA 151
BMPR1B          ---------------------------------------TCCIAD-LGLA 151
IRAK1           ---------------------------------------TPKLGD-FGLA 151
IRAK2           ---------------------------------------TPKLAHPMAH- 148
IRAK3           ---------------------------------------QPKLTD-FAMA 151
MISR2           ---------------------------------------SCAIGD-LGLA 153
MYT1            ---------------------------------------RCKLGD-FGLL 146
SBK             ---------------------------------------RVKLAD-FGMT 146
SGK110          ---------------------------------------RVALGD-LGLT 145
SGK069          ---------------------------------------RFKLTD-FGHT 146
SGK496          ---------------------------------------RAKITD-LGFC 148
NIK             ---------------------------------------HAALCD-FGHA 139
SGK424          -------------------------------------------------- 0
SURTK106        ---------------------------------------TAKLCG-LGLA 160
IKKE            ---------------------------------------IYKLTD-FGAA 153
TBK1            ---------------------------------------VYKLTD-FGAA 153
MOS             ---------------------------------------VCKISD-FGCS 164
LKB1            ---------------------------------------TLKISD-LGVA 150
CAMKK1          ---------------------------------------HVKIAD-FGVS 178
CAMKK2          ---------------------------------------HIKIAD-FGVS 170
PASK            ---------------------------------------TIKLID-FGSA 152
PIM1            ---------------------------------------ELKLID-FGSG 153
PIM3            ---------------------------------------ELKLID-FGSG 154
PIM2            ---------------------------------------CAKLID-FGSG 155
COT             ---------------------------------------AV-LVD-FGLS 139
SCYL2           ---------------------------------------AWKIMG-FDFC 169
FUSED           ---------------------------------------GIKLCD-FGF- 143
ULK1            ---------------------------------------RVKIAD-FGF- 153
ULK2            ---------------------------------------RIKIAD-FGF- 153
ULK3            ---------------------------------------HLKLAD-FGF- 147
ULK4            ---------------------------------------TLKFSN-FCL- 124
IRE1            ---------------------------------------KAMISD-FGL- 144
IRE2            ---------------------------------------RVVLSD-FGL- 144
RNASEL          ---------------------------------------AAHLAD-FDKS 139
MPSK1           ---------------------------------------QPVLMD-LGSM 151
PINK1           ---------------------------------------WLVIAD-FG-- 231
ALK             ---------------------------------------VAKIGD-FGMA 159
LTK             ---------------------------------------VAKIGD-FGMA 159
ROS             ---------------------------------------IVKIGD-FGLA 162
IGF1R           ---------------------------------------TVKIGD-FGMT 159
1IR3A           ---------------------------------------TVKIGD-FGMT 159
INSR            ---------------------------------------TVKIGD-FGMT 159
IRR             ---------------------------------------TVKIGD-FGMT 159
1M14A           ---------------------------------------HVKITD-FGLA 148
EGFR            ---------------------------------------HVKITD-FGLA 148
HER2/ERBB2      ---------------------------------------HVKITD-FGLA 148
HER4/ERBB4      ---------------------------------------HVKITD-FGLA 148
HER3/ERBB3      ---------------------------------------QVQVAD-FGVA 148
ITK             ---------------------------------------VIKVSD-FGMT 142
TEC             ---------------------------------------VVKVSD-FGMA 142
TXK             ---------------------------------------IVKISD-FGMT 142
BMX             ---------------------------------------CVKVSD-FGMT 142
1K2PA           ---------------------------------------VVKVSD-FGLS 142
BTK             ---------------------------------------VVKVSD-FGLS 142
CCK4            ---------------------------------------QVKVSA-LGLS 157
ROR1            ---------------------------------------HVKISD-LGLS 165
ROR2            ---------------------------------------NVKISD-LGLF 165
MUSK            ---------------------------------------VVKIAD-FGLS 173
TRKA            ---------------------------------------VVKIGD-FGMS 163
TRKB            ---------------------------------------LVKIGD-FGMS 161
TRKC            ---------------------------------------LVKIGD-FGMS 164
DDR1            ---------------------------------------TIKIAD-FGMS 179
DDR2            ---------------------------------------TIKIAD-FGMS 170
RYK             ---------------------------------------QVKITD-NALS 158
JAK1            ---------------------------------------QVKIGD-FGLT 150
JAK2            ---------------------------------------RVKIGD-FGLT 150
JAK3            ---------------------------------------HVKIAD-FGLA 150
ACK             ---------------------------------------LVKIGD-FGLM 149
TYK2            ---------------------------------------LVKIGD-FGLA 149
TNK1            ---------------------------------------TIKVAD-FGLV 152
EPHA1           ---------------------------------------CCKVSD-FGLT 148
EPHA10          ---------------------------------------VCKISG-FG-- 146
FAK             ---------------------------------------CVKLGD-FGLS 147
EPHB6           ---------------------------------------VCKVAR-LG-- 146
EPHA2           ---------------------------------------VCKVSD-FGLS 149
EPHA8           ---------------------------------------VCKVSD-FGLS 148
EPHA6           ---------------------------------------VCKVSD-FGLS 190
EPHB1           ---------------------------------------VCKVSD-FGLS 148
EPHB2           ---------------------------------------VCKVSD-FGLS 148
EPHB3           ---------------------------------------VCKVSD-FGLS 148
EPHB4           ---------------------------------------VCKVSD-FGLS 148
EPHA7           ---------------------------------------VCKVSD-FGLS 148
EPHA4           ---------------------------------------VCKVSD-FGMS 148
EPHA3           ---------------------------------------VCKVSD-FGLS 148
EPHA5           ---------------------------------------VCKVSD-FGLS 148
PYK2            ---------------------------------------CVKLGD-FGLS 147
CSK             ---------------------------------------VAKVSD-FGLT 142
CTK             ---------------------------------------VAKVSD-FGLA 140
1IEPA           ---------------------------------------LVKVAD-FGLS 144
ABL             ---------------------------------------LVKVAD-FGLS 144
ARG             ---------------------------------------VVKVAD-FGLS 144
BRK             ---------------------------------------LCKVGD-FGLA 144
SRM             ---------------------------------------ACKVAD-FGLA 143
FRK             ---------------------------------------IYKVAD-FGLA 143
FGR             ---------------------------------------ACKIAD-FGLA 142
FYN             ---------------------------------------ICKIAD-FGLA 142
SRC             ---------------------------------------VCKVAD-FGLA 142
YES             ---------------------------------------VCKIAD-FGLA 142
HCK             ---------------------------------------VCKIAD-FGLA 142
LYN             ---------------------------------------MCKIAD-FGLA 143
3LCK            ---------------------------------------SCKIAD-FGLA 142
LCK             ---------------------------------------SCKIAD-FGLA 142
BLK             ---------------------------------------CCKIAD-FGLA 142
FER             ---------------------------------------VLKISD-FGMS 144
FES             ---------------------------------------VLKISD-FGMS 145
SYK             ---------------------------------------YAKISD-FGLS 146
ZAP70           ---------------------------------------YAKISD-FGLS 146
FGFR1           ---------------------------------------VMKIAD-FGLA 168
FGFR2           ---------------------------------------VMKIAD-FGLA 168
FGFR3           ---------------------------------------VMKIAD-FGLA 168
FGFR4           ---------------------------------------VMKIAD-FGLA 168
RET             ---------------------------------------KMKISD-FGLS 173
TIE1            ---------------------------------------ASKIAD-FGLS 163
1FVRA           ---------------------------------------VAKIAD-FGLS 163
TIE2            ---------------------------------------VAKIAD-FGLS 163
FLT1            ---------------------------------------VVKICD-FGLA 218
KDR             ---------------------------------------VVKICD-FGLA 217
KDR_AVE         ---------------------------------------VVKICD-FG-- 158
FLT4            ---------------------------------------VVKICD-FGLA 215
FMS             ---------------------------------------VAKIGD-FGLA 219
FLT3            ---------------------------------------VVKICD-FGLA 224
KIT             ---------------------------------------ITKICD-FGLA 226
PDGFRA          ---------------------------------------IVKICD-FGLA 248
PDGFRB          ---------------------------------------LVKICD-FGLA 249
MER             ---------------------------------------TVCVAD-FGLS 159
AXL             ---------------------------------------SVCVAD-FGLS 159
TYRO3           ---------------------------------------TVCVAD-FGLS 160
MET             ---------------------------------------TVKVAD-FGLA 149
RON             ---------------------------------------TVKVAD-FGLA 149
HH498           ---------------------------------------HAVVAD-FGES 148
LZK             ---------------------------------------AVKISD-FGTS 134
DLK             ---------------------------------------VVKISD-FGTS 134
MLK1            ---------------------------------------ILKITD-FGLA 155
MLK3            ---------------------------------------TLKITD-FGLA 155
MLK2            ---------------------------------------VLKITD-FGLA 155
MLK4            ---------------------------------------TLKITD-FGLA 170
ZAK             ---------------------------------------VLKICD-FGAS 140
TAK1            ---------------------------------------VLKICD-FGTA 144
KSR1            ---------------------------------------KVVITD-FGLF 142
KSR2            ---------------------------------------KVVITD-FGLF 142
ARAF            ---------------------------------------TVKIGD-FGLA 142
RAF1            ---------------------------------------TVKIGD-FGLA 142
BRAF            ---------------------------------------TVKIGD-FGLA 142
LRRK2           ---------------------------------------IAKIAD-YGIA 143
ANKRD3          ---------------------------------------HVKISD-FGLA 144
SGK288          ---------------------------------------HVKISD-FGLS 143
RIPK2           ---------------------------------------HVKIAD-FGLS 151
RIPK3           ---------------------------------------HVKLAD-FGLS 144
MLKL            ---------------------------------------QVKLAG-FELR 146
ANPA            ---------------------------------------VLKITD-YGLE 148
ANPB            ---------------------------------------VLKITD-YGLA 148
CYGD            ---------------------------------------VLKITD-HGHG 156
CYGF            ---------------------------------------VLKVTD-YGFN 161
TBCK            ---------------------------------------HIKLAK-FGLY 121
ERK1            ---------------------------------------DLKICD-FGLA 147
3ERK            ---------------------------------------DLKICD-FGLA 147
ERK2            ---------------------------------------DLKICD-FGLA 147
ERK5            ---------------------------------------ELKIGD-FGMA 150
1JNK            ---------------------------------------TLKILD-FGLA 148
1PMNA           ---------------------------------------TLKILD-FGLA 148
JNK3            ---------------------------------------TLKILD-FGLA 148
JNK1            ---------------------------------------TLKILD-FGLA 148
JNK2            ---------------------------------------TLKILD-FGLA 148
1P38            ---------------------------------------ELKILD-FGLA 149
P38A            ---------------------------------------ELKILD-FGLA 149
P38B            ---------------------------------------ELRILD-FGLA 157
P38D            ---------------------------------------ELKILD-FGLA 148
P38G            ---------------------------------------ELKILD-FGLA 149
NLK             ---------------------------------------VLKICD-FGLA 149
ERK7            ---------------------------------------TVKLCD-FGLA 166
ERK3            ---------------------------------------VLKIGD-FGLA 156
ERK4            ---------------------------------------VLKIGD-FGLA 153
ICK             ---------------------------------------LVKIAD-FGLA 144
MAK             ---------------------------------------LVKIAD-FGLA 144
PCTAIRE1        ---------------------------------------ELKLAD-FGLA 144
PCTAIRE2        ---------------------------------------ELKLAD-FGLA 144
PCTAIRE3        ---------------------------------------ELKLAD-FGLA 144
PFTAIRE1        ---------------------------------------ELKLAD-FGLA 144
PFTAIRE2        ---------------------------------------ELKLAD-FGLA 144
CDC2            ---------------------------------------TIKLAD-FGLA 147
1HCL            ---------------------------------------AIKLAD-FGLA 142
CDK2            ---------------------------------------AIKLAD-FGLA 146
CDK3            ---------------------------------------AIKLAD-FGLA 146
CDK5            ---------------------------------------ELKLAD-FGLA 145
CDK7            ---------------------------------------VLKLAD-FGLA 148
CDK4            ---------------------------------------TVKLAD-FGLA 157
1BLXA           ---------------------------------------QIKLAD-FGLA 155
CDK6            ---------------------------------------QIKLAD-FGLA 155
PITSLRE         ---------------------------------------ILKVGD-FGLA 147
CDK10           ---------------------------------------CVKTAD-FGLA 147
CDK9            ---------------------------------------VLKLAD-FGLA 153
CHED            ---------------------------------------QIKLAD-FGLA 155
CRK7            ---------------------------------------QIKLAD-FGLA 155
CCRK            ---------------------------------------QLKIAD-FGLA 146
CDK11           ---------------------------------------RVKIAD-MGFA 158
CDK8            ---------------------------------------RVKIAD-MGFA 158
IKKA            ---------------------------------------IHKIID-LGYA 155
IKKB            ---------------------------------------IHKIID-LGYA 156
1PHK            ---------------------------------------NIKLTD-FGFS 153
PHKG1           ---------------------------------------NIKLTD-FGFS 153
PHKG2           ---------------------------------------QIRLSD-FGFS 152
CAMK2A          ---------------------------------------AVKLAD-FGLA 148
CAMK2B          ---------------------------------------AVKLAD-FGLA 148
CAMK2G          ---------------------------------------AVKLAD-FGLA 148
CAMK2D          ---------------------------------------AVKLAD-FGLA 148
CASK            ---------------------------------------PVKLGG-FGVA 155
1IA8A           ----------------------------------------LKISD-FGLA 141
CHK1            ----------------------------------------LKISD-FGLA 144
CLK1            ---------------------------------------DIKVVD-FGSA 169
CLK4            ---------------------------------------DIKVVD-FGSA 168
CLK2            ---------------------------------------AVRVVD-FGSA 169
CLK3            ---------------------------------------SIRVAD-FGSA 169
MAP2K5          ---------------------------------------QVKLCD-FGVS 140
MAP2K3          ---------------------------------------HVKMCD-FGIS 149
MAP2K6          ---------------------------------------QVKMCD-FGIS 149
MAP2K4          ---------------------------------------NIKLCD-FGIS 150
MAP2K7          ---------------------------------------QIKLCD-FGIS 146
MAP2K1          ---------------------------------------EIKLCD-FGVS 145
MAP2K2          ---------------------------------------EIKLCD-FGVS 145
CDKL5           ---------------------------------------VLKLCD-FGFA 145
CDKL1           ---------------------------------------VIKLCD-FGFA 145
CDKL4           ---------------------------------------IIKICD-FGFA 145
CDKL2           ---------------------------------------VVKLCD-FGFA 145
CDKL3           ---------------------------------------ITKLCD-FGFA 144
1I09B           ---------------------------------------VLKLCD-FGSA 149
GSK3B           ---------------------------------------VLKLCD-FGSA 149
1J1BA           ---------------------------------------VLKLCD-FGSA 149
GSK3A           ---------------------------------------VLKLCD-FGSA 149
LATS1           ---------------------------------------HIKLTD-FGLC 146
LATS2           ---------------------------------------HIKLTD-FGLC 146
NDR1            ---------------------------------------HVKLSD-FGLC 146
NDR2            ---------------------------------------HVKLSD-FGLC 146
MAST1           ---------------------------------------HIKLTD-FGLS 146
MAST4           ---------------------------------------HIKLTD-FGLS 146
MAST2           ---------------------------------------HIKLTD-FGLS 146
MAST3           ---------------------------------------HIKLTD-FGLS 146
MRCKA           ---------------------------------------HIRLAD-FGSC 147
MRCKB           ---------------------------------------HIRLAD-FGSC 147
DMPK2           ---------------------------------------HIRLAD-FGSC 147
DMPK1           ---------------------------------------HIRLAD-FGSC 147
ROCK1           ---------------------------------------HLKLAD-FGTC 145
ROCK2           ---------------------------------------HLKLAD-FGTC 145
CRIK            ---------------------------------------HIKLVD-FGSA 147
MASTL           ---------------------------------------HIKLTD-FGLS 144
1O6LA           ---------------------------------------HIKITD-FGLC 146
AKT2            ---------------------------------------HIKITD-FGLC 146
AKT1            ---------------------------------------HIKITD-FGLC 147
AKT3            ---------------------------------------HIKITD-FGLC 146
MSK1            ---------------------------------------HVVLTD-FGLS 151
MSK2            ---------------------------------------HIVLTD-FGLS 151
P70S6K          ---------------------------------------HVKLTD-FGLC 150
P70S6KB         ---------------------------------------HIKLTD-FGLC 150
RSK1            ---------------------------------------HIKITD-FGLS 148
RSK3            ---------------------------------------HIKLTD-FGLS 148
RSK2            ---------------------------------------HIKLTD-FGLS 148
RSK4            ---------------------------------------HIKLTD-FGLS 148
1FOTA           ---------------------------------------HIKITD-FGFA 146
1CDKA           ---------------------------------------YIQVTD-FGFA 146
PKACA           ---------------------------------------YIQVTD-FGFA 146
PKACB           ---------------------------------------YIQVTD-FGFA 146
PKACG           ---------------------------------------YLQVTD-FGFA 146
PRKX            ---------------------------------------HIKLTD-FGFA 146
PRKY            ---------------------------------------HIKLTD-FGFA 146
PKCA            ---------------------------------------HIKIAD-FGMC 147
PKCB            ---------------------------------------HIKIAD-FGMC 147
PKCG            ---------------------------------------HIKITD-FGMC 152
PKCE            ---------------------------------------HCKLAD-FGMC 147
PKCH            ---------------------------------------HCKLAD-FGMC 147
PKCD            ---------------------------------------HIKIAD-FGMC 147
PKCT            ---------------------------------------HIKIAD-FGMC 147
PKCI            ---------------------------------------HIKLTD-YGMC 147
PKCZ            ---------------------------------------HIKLTD-YGMC 147
PKN1            ---------------------------------------YVKIAD-FGLC 148
PKN2            ---------------------------------------FVKIAD-FGLC 148
PKN3            ---------------------------------------FLKIAD-FGLC 148
SGK             ---------------------------------------HIVLTD-FGLC 147
SGK2            ---------------------------------------HVVLTD-FGLC 147
SGK3            ---------------------------------------HVVLTD-FGLC 147
PKG1            ---------------------------------------YAKLVD-FGFA 147
PKG2            ---------------------------------------YLKLVD-FGFA 146
AURB            ---------------------------------------ELKIAD-FGWS 146
AURC            ---------------------------------------EVKIAD-FGWS 146
AURA            ---------------------------------------ELKIAD-FGWS 146
AURORA2_AVE     ---------------------------------------ELKIAD-FGWS 146
PLK1            ---------------------------------------EVKIGD-FGLA 146
PLK2            ---------------------------------------ELKVGD-FGLA 146
PLK3            ---------------------------------------ELKVGD-FGLA 146
PLK4            ---------------------------------------NIKIAD-FGLA 147
NEK11           ----------------------------------------LKIGD-FGVS 151
YANK1           ---------------------------------------HVHITD-FNIA 146
YANK2           ---------------------------------------HVHITD-FNIA 146
YANK3           ---------------------------------------HAHLTD-FNIA 146
SGK494          ---------------------------------------HLKLTD-FGLS 145
DOMAIN2_MSK1    ---------------------------------------EIKIID-FGFA 144
DOMAIN2_MSK2    ---------------------------------------PVKIID-FGFA 139
DOMAIN2_RSK1    ---------------------------------------SIRVCD-FGFA 144
DOMAIN2_RSK2    ---------------------------------------SIRICD-FGFA 144
DOMAIN2_RSK3    ---------------------------------------CLRICD-FGFA 144
DOMAIN2_RSK4    ---------------------------------------SIRICD-FGFA 144
DRAK1           ---------------------------------------DIKIVD-FGLS 151
DRAK2           ---------------------------------------DIKIVD-FGMS 151
1JKSA           ---------------------------------------RIKIID-FGLA 153
DAPK1           ---------------------------------------RIKIID-FGLA 153
DAPK3           ---------------------------------------RIKLID-FGIA 153
DAPK2           ---------------------------------------HIKLID-FGLA 153
SGK085          ---------------------------------------QIKIID-FGLA 146
CAMLCK          ---------------------------------------QIKIID-FGLA 146
SKMLCK          ---------------------------------------LVKIID-FGLA 146
SMMLCK          ---------------------------------------RIKLID-FGLA 146
1KOBA           ---------------------------------------SVKIID-FGLA 146
1TKIA           ---------------------------------------TIKIIE-FGQA 145
TTN             ---------------------------------------TIKIIE-FGQA 145
PKD1            ---------------------------------------QVKLCD-FGFA 149
PKD3            ---------------------------------------QVKLCD-FGFA 149
PKD2            ---------------------------------------QVKLCD-FGFA 149
PSKH1           ---------------------------------------KIIITD-FGLA 146
PSKH2           ---------------------------------------KILITD-FGLA 146
CAMK1A          ---------------------------------------KIMISD-FGLS 147
CAMK1D          ---------------------------------------KIMISD-FGLS 147
CAMK1B          ---------------------------------------KIMVSD-FGLS 147
CAMK1G          ---------------------------------------KIMITD-FGLS 146
CAMK4           ---------------------------------------PLKIAD-FGLS 144
DCAMKL1         ---------------------------------------SLKLGD-FGLA 148
DCAMKL2         ---------------------------------------SLKLGD-FGLA 148
DCAMKL3         ---------------------------------------TLKLAD-FGLA 148
CHK2            ---------------------------------------LIKITD-FGHS 153
MAPKAPK2        ---------------------------------------ILKLTD-FGFA 148
MAPKAPK3        ---------------------------------------VLKLTD-FGFA 148
MAPKAPK5        ---------------------------------------PVKLCD-FGFA 152
MNK1            ---------------------------------------PVKICD-FDLG 148
MNK2            ---------------------------------------PVKICD-FDLG 147
VACAMKL         ---------------------------------------KIVISD-FHLA 147
GCK             ----------------------------------------VKLAD-FGVS 143
KHS1            ----------------------------------------VKLAD-FGVA 143
KHS2            ----------------------------------------VKLAD-FGVS 143
HPK1            ----------------------------------------VRLAD-FGIS 143
MST1            ----------------------------------------AKLAD-FGVA 142
MST2            ----------------------------------------AKLAD-FGVA 142
MST3            ----------------------------------------VKLAD-FGVA 143
YSK1            ----------------------------------------VKLAD-FGVA 143
MST4            ----------------------------------------VKLAD-FGVA 143
LOK             ----------------------------------------IRLAD-FGVS 144
SLK             ----------------------------------------IKLAD-FGVS 144
MAP3K4          ----------------------------------------IKLGD-FGCS 143
MAP3K2          ----------------------------------------VKLGD-FGAS 150
MAP3K3          ----------------------------------------VKLGD-FGAS 150
MAP3K8          ----------------------------------------IKLID-FGCA 148
MAP3K5          ----------------------------------------LKISD-FGTS 152
MAP3K7          ----------------------------------------VKISD-FGTS 143
MAP3K6          ----------------------------------------LKISD-FGTS 142
PAK1            ----------------------------------------VKLTD-FGFC 142
PAK3            ----------------------------------------VKLTD-FGFC 142
PAK2            ----------------------------------------VKLTD-FGFC 143
PAK4            ----------------------------------------VKLSD-FGFC 142
PAK5            ----------------------------------------IKLSD-FGFC 142
PAK6            ----------------------------------------VKLSD-FGFC 142
OSR1            ----------------------------------------VQIAD-FGVS 152
STLK3           ----------------------------------------VQIAD-FGVS 152
TAO1            ----------------------------------------VKLAD-FGSA 146
TAO3            ----------------------------------------VKLAD-FGSA 146
TAO2            ----------------------------------------VKLGD-FGSA 146
MYO3A           ----------------------------------------VKLVD-FGVS 152
MYO3B           ----------------------------------------VKLVD-FGVS 152
ZC1/HGK         ----------------------------------------VKLVD-FGVS 151
ZC3/MINK        ----------------------------------------VKLVD-FGVS 151
ZC2/TNIK        ----------------------------------------VKLVD-FGVS 151
ZC4/NRK         ----------------------------------------VKLVD-FGVS 175
MAP3K1          ---------------------------------------RLRIAD-FGAA 150
GAK             ----------------------------------------IKLCD-FGSA 156
SGK495          ---------------------------------------RITITN-FCLG 63
TRB1            ---------------------------------------QLRLES-LEDT 131
TRB2            ---------------------------------------RVKLES-LEDA 136
TRB3            ---------------------------------------KLVLEN-LEDS 134
SSTK            ----------------------------------------VKLTD-FGFG 147
TSSK3           ----------------------------------------LKLTD-FGFA 146
TSSK1           ----------------------------------------IKLSD-FSFS 147
TSSK2           ----------------------------------------IKLSD-FGFS 147
TSSK4           ----------------------------------------VKISD-FGFA 146
HUNK            ----------------------------------------IKLID-FGLS 148
SNRK            ----------------------------------------VKLTD-FGFS 147
NIM1            ----------------------------------------VKVGD-FGFS 145
MELK            ----------------------------------------LKLID-FGLC 144
BRSK1           ----------------------------------------IRIAD-FGMA 145
BRSK2           ----------------------------------------IRIAD-FGMA 145
MARK1           ----------------------------------------IKIAD-FGFS 145
MARK2           ----------------------------------------IKIAD-FGFS 145
MARK3           ----------------------------------------IKIAD-FGFS 145
MARK4           ----------------------------------------IKIAD-FGFS 145
QIK             ----------------------------------------IKIAD-FGFG 145
SIK             ----------------------------------------IKLAD-FGFG 145
QSK             ----------------------------------------IKIAD-FGFS 145
AMPKA1          ----------------------------------------AKIAD-FGLS 146
AMPKA2          ----------------------------------------AKIAD-FGLS 146
NUAK1           ----------------------------------------IKIAD-FGLS 146
NUAK2           ----------------------------------------IKIAD-FGLS 145
BIKE            ----------------------------------------YVLCD-FGSA 152
AAK1            ----------------------------------------YVLCD-FGSA 153
LIMK1           ---------------------------------------V-VVAD-FGLA 144
LIMK2           ---------------------------------------V-VVAD-FGLS 143
TESK1           ---------------------------------------A-VVGD-FGLA 144
TESK2           ---------------------------------------A-VVAD-FGLA 124
WNK1            ---------------------------------------V-KIGD-LGLA 152
WNK3            ---------------------------------------V-KIGD-LGLA 152
WNK2            ---------------------------------------V-KIGD-LGLA 152
WNK4            ---------------------------------------V-KIGD-LGLA 152
NEK10           ---------------------------------------V-TVTD-FGLA 159
NEK6            ---------------------------------------V-KLGD-LGLG 150
NEK7            ---------------------------------------V-KLGD-LGLG 150
NEK2            ---------------------------------------V-KLGD-FGLA 156
NEK1            ---------------------------------------V-QLGD-FGIA 147
NEK5            ---------------------------------------VAKLGD-FGIA 148
NEK3            ---------------------------------------V-KLGD-FGSA 146
NEK4            ---------------------------------------I-KVGD-LGIA 148
NEK8            ---------------------------------------V-KIGD-FGIS 148
NEK9            ---------------------------------------I-KLGD-YGLA 147
NRBP1           ---------------------------------------I-KIGS-VAP- 159
NRBP2           ---------------------------------------I-KIGS-VW-H 159
CLIK1           ---------------------------------------ILKVAD-FGLS 184
CLIK1L          ---------------------------------------TLKVAD-FGLS 187
STK33           ---------------------------------------NIKVTD-FGLA 154
DOMAIN2_GCN2    ----------------------------------------VKITD-YSIS 168
SCYL1           ----------------------------------------WKLGG-LDYM 135
SCYL3           ----------------------------------------WKLGG-METV 122
DOMAIN2_JAK1    ---------------------SECGP-------------FIKLSD-PGIP 161
DOMAIN2_TYK2    ---------------------EGTSP-------------FIKLSD-PGVG 175
DOMAIN2_JAK2    ---------------------TGNPP-------------FIKLSD-PGIS 159
DOMAIN2_JAK3    ---------------------DGSPP-------------FIKLSD-PGVS 155
ILK             ----------------------------------------ARISM-ADV- 148
LRRK1           ------------------------------------EHINIKLSD-YGIS 172
PBK             --------------------------------------ETIKICD-VGVS 159
WEE1            ---------------------NAASEEGDEDDW-ASNKVMFKIGD-LGHV 169
WEE1B           ---------------------GVIEEVENEADWFLSANVMYKIGD-LGHA 173
SGK071          ----------------------------------------CKLQD-LSSN 152
PIK3R4          ----------------------------------------VLLTD-FASF 145
MSSK1           ---------------SPSTPFGASNLLVNPLEPQNADKIKIKIAD----- 297
SRPK1           IPCEDEQEQEHNGPLDNKGKSTAGNFLVNPLEPKNAEKLKVKIAD----- 418
SRPK2           VSASSTGDLP-------KAKTRAADLLVNPLDPRNADKIRVKIAD----- 450
RSKL1           ----------------------------------------IQLTY-FSRW 130
RSKL2           ----------------------------------------IRLTY-FGQW 282
SGK396          ----------------------------------------GIVGD-FDFT 144
VRK1            ---------------------------------------QVYLVD-YGLA 165
VRK2            ---------------------------------------QVYLAD-YGLS 162
VRK3            ---------------------------------------QVTLAG-YGFA 110
BUB1            ----------------------------------DDLSAGLALID-LGQS 164
BUBR1           ----------------------------------NKNNQALKIVD-FSYS 163
SGK196          ---------------------------------LLTSNFSILAND-LDAL 151
SGK493          ----------------------------------------LKVTD-LDDA 159
                                                                  

DYRK1A          CQLGQRI------------------------------------------- 160
DYRK1B          CQLGQRI------------------------------------------- 160
DYRK2           CYEHQRV------------------------------------------- 158
DYRK3           CFEYQKL------------------------------------------- 158
DYRK4           CYEHQKV------------------------------------------- 158
HIPK1           SHVSKAVC------------------------------------------ 160
HIPK2           SHVSKAVC------------------------------------------ 160
HIPK3           SHVSKTVC------------------------------------------ 160
HIPK4           SIFSEVRYVKE--------------------------------------- 163
PRP4            SHVADNDI------------------------------------------ 160
MOK             RSVYSKQPY----------------------------------------- 155
1A6O            EFYHPGKEY----------------------------------------- 150
1LPUA           EFYHPGKEY----------------------------------------- 150
CK2A1           EFYHPGQEY----------------------------------------- 150
CK2A1-RS        EFYHPGQEY----------------------------------------- 150
CK2A2           EFYHPAQEY----------------------------------------- 150
HSER            SILPPKKD------------------------------------------ 156
SLOB            SFYRS--------------------------------------------- 171
CDC7            QGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSGPVPKELDQQS 193
1CSN            KFYRDPVTKQ------------------HIPYRE---------------- 163
CK1G1           KEYIDPETKK------------------HIPYRE---------------- 164
CK1G3           KEYIDPETKK------------------HIPYRE---------------- 163
CK1G2           KEYIDPETKK------------------HIPYRE---------------- 163
CK1A            KKYRDNRTRQ------------------HIPYRE---------------- 161
CK1A2           KKYRDNRTRQ------------------HIPYRE---------------- 161
1CKJA           KKYRDARTHQ------------------HIPYRE---------------- 161
CK1D            KKYRDARTHQ------------------HIPYRE---------------- 161
CK1E            KKYRDARTHQ------------------HIPYRE---------------- 161
TTBK1           RQYTNTTGD-------------------VRPPRN---------------- 162
TTBK2           RQFTNSCGD-------------------VRPPRA---------------- 162
TLK1            KIMDDDSYG-VD------------------GMDL---------------- 171
TLK2            KIMDDDSYNSVD------------------GMEL---------------- 172
GPRK4           TEIPEGQRV----------------------------------------- 157
GPRK6           VHVPEGQTI----------------------------------------- 157
GPRK5           VKIPEGDLI----------------------------------------- 157
RHOK            VELLDGQSKT---------------------------------------- 160
GPRK7           VEMKGGKPI----------------------------------------- 157
BARK1           CDFSKKKP------------------------------------------ 157
BARK2           CDFSKKKP------------------------------------------ 157
TTK             NQMQPDTTSVVK-------------------------------------- 156
RIPK1           SFKMWSKLNNEE----------------HNELRE---------------- 162
HASPIN          RLERDGIVVF------------------CDVSMDEDLF------------ 228
GCN2            TDHLAFSADSKQDDQTGDLIKS---------------------------- 303
HRI             CTDIL----QKNTDWTNRNGKR---------------------------- 317
KIS             FKEGN-----QDVKYIQT-------------------------------- 172
PDK1            KVLS------PESKQ----------------------------------- 155
PKR             TS-----------------LKN---------------------------- 175
PEK             TA-----MDQDEEEQTV-LTPM---------------------------- 383
PRPK            FISAL-----PEDK------------------------------------ 164
DOMAIN2_OBSCN   -------------------------------------------------- 139
DOMAIN2_SPEG    -------------------------------------------------- 139
LMR1            -------------------------------------------------- 148
LMR2            -------------------------------------------------- 148
LMR3            -------------------------------------------------- 153
SGK307          -------------------------------------------------- 58
STLK5           -------------------------------------------------- 146
STLK6           -------------------------------------------------- 146
STLK6-RS        -------------------------------------------------- 146
OBSCN           -------------------------------------------------- 141
SPEG            -------------------------------------------------- 142
TRAD            -------------------------------------------------- 142
TRIO            -------------------------------------------------- 142
SGK223          PAPAPAAAAPPCSSAAPPAG------------------------------ 170
SGK269          --------YQP--------G------------------------------ 145
ALK1            VMHSQGS-------DYLDI------------------------------- 163
ALK2            VMHSQST-------NQLDV------------------------------- 163
IRAK4           RASEKFA---------QTV------------------------------- 158
BMPR2           MRLTGNRLVR---PGEEDN------------------------------- 169
TGFBR2          LRLDPTL-------SVDDL------------------------------- 170
ACTR2           LKFEAGK-------SAGD-------------------------------- 164
ACTR2B          VRFEPGK-------PPGD-------------------------------- 165
1B6CB           VRHDSAT-------DTIDI------------------------------- 163
TGFBR1          VRHDSAT-------DTIDI------------------------------- 163
ALK4            VRHDAVT-------DTIDI------------------------------- 163
ALK7            VKHDSIL-------NTIDI------------------------------- 163
BMPR1A          VKFNSDT-------NEVDV------------------------------- 163
BMPR1B          VKFISDT-------NEVDI------------------------------- 163
IRAK1           RFSR--FAGSSPSQSSMVA------------------------------- 168
IRAK2           L------------------------------------------------- 149
IRAK3           H------------------------------------------------- 152
MISR2           L------------------------------------------------- 154
MYT1            V------------------------------------------------- 147
SBK             R------------------------------------------------- 147
SGK110          R------------------------------------------------- 146
SGK069          R------------------------------------------------- 147
SGK496          K------------------------------------------------- 149
NIK             V------------------------------------------------- 140
SGK424          -------------------------------------------------- 0
SURTK106        Y------------------------------------------------- 161
IKKE            RELDD----------D---------------------------------- 159
TBK1            RELED----------D---------------------------------- 159
MOS             EKLED-------LLCFQ--------------------------------- 174
LKB1            EALHP-------FAAD---------------------------------- 159
CAMKK1          NQFEG---------ND---------------------------------- 185
CAMKK2          NEFKG---------SD---------------------------------- 177
PASK            AYLER----------G---------------------------------- 158
PIM1            ALLKD--------------------------------------------- 158
PIM3            ALLKD--------------------------------------------- 159
PIM2            ALLHD--------------------------------------------- 160
COT             VQMTE-------DVYFP--------------------------------- 149
SCYL2           VSSTNPSEQEPKFPCKEWD------------------------------- 188
FUSED           ---ARAMSTNTMVL------------------------------------ 154
ULK1            ---ARYLQSN---------------------------------------- 160
ULK2            ---ARYLHSN---------------------------------------- 160
ULK3            ---AQHMSPW---------------------------------------- 154
ULK4            ---AKVEGENL-EE------------------------------------ 134
IRE1            ---CKKLAVGRH-------------------------------------- 153
IRE2            ---CKKLPAGRC-------------------------------------- 153
RNASEL          IK------------------------------------------------ 141
MPSK1           NQACIHVEGSRQAL------------------------------------ 165
PINK1           --CCLADESIGLQL------------------------------------ 243
ALK             RDIYR-AS------------------------------------------ 166
LTK             RDIYR-AS------------------------------------------ 166
ROS             RDIYK-ND------------------------------------------ 169
IGF1R           RDIYE-TD------------------------------------------ 166
1IR3A           RDIYE-TD------------------------------------------ 166
INSR            RDIYE-TD------------------------------------------ 166
IRR             RDVYE-TD------------------------------------------ 166
1M14A           KLLGAEEK------------------------------------------ 156
EGFR            KLLGAEEK------------------------------------------ 156
HER2/ERBB2      RLLDIDET------------------------------------------ 156
HER4/ERBB4      RLLEGD-E------------------------------------------ 155
HER3/ERBB3      DLLPPD-D------------------------------------------ 155
ITK             RFVLD-DQ------------------------------------------ 149
TEC             R-YFLD-D------------------------------------------ 148
TXK             RYVLD-DE------------------------------------------ 149
BMX             RYVLD-DQ------------------------------------------ 149
1K2PA           RYVLD-DE------------------------------------------ 149
BTK             RYVLD-DE------------------------------------------ 149
CCK4            KDVYN-SE------------------------------------------ 164
ROR1            REIYS-AD------------------------------------------ 172
ROR2            REVYA-AD------------------------------------------ 172
MUSK            RNIYS-AD------------------------------------------ 180
TRKA            RDIYS-TD------------------------------------------ 170
TRKB            RDVYS-TD------------------------------------------ 168
TRKC            RDVYS-TD------------------------------------------ 171
DDR1            RNLYA-GD------------------------------------------ 186
DDR2            RNLYS-GD------------------------------------------ 177
RYK             RDLFP-MD------------------------------------------ 165
JAK1            KAIETDKE------------------------------------------ 158
JAK2            KVLPQDKE------------------------------------------ 158
JAK3            KLLPLDKD------------------------------------------ 158
ACK             RALPQNDD------------------------------------------ 157
TYK2            KAVPEGHE------------------------------------------ 157
TNK1            RPLGGARG------------------------------------------ 160
EPHA1           RLL-DDF-DGTYET------------------------------------ 160
EPHA10          RGPRDRS-EAVYTT------------------------------------ 159
FAK             RYMEDS---TYYKA------------------------------------ 158
EPHB6           -----------HSP------------------------------------ 149
EPHA2           RVLEDDP-EATYTT------------------------------------ 162
EPHA8           RVLEDDP-DAAYTT------------------------------------ 161
EPHA6           RVLEDDP-EAAYTT------------------------------------ 203
EPHB1           RYLQDDTSDPTYTS------------------------------------ 162
EPHB2           RFLEDDTSDPTYTS------------------------------------ 162
EPHB3           RFLEDDPSDPTYTS------------------------------------ 162
EPHB4           RFLEENSSDPTYTS------------------------------------ 162
EPHA7           RVIEDDP-EAVYTT------------------------------------ 161
EPHA4           RVLEDDP-EAAYTT------------------------------------ 161
EPHA3           RVLEDDP-EAAYTT------------------------------------ 161
EPHA5           RVLEDDP-EAAYTT------------------------------------ 161
PYK2            RYIED---EDYYKA------------------------------------ 158
CSK             KEAS-------STQ------------------------------------ 149
CTK             KA-------ERKGL------------------------------------ 147
1IEPA           RLMT-G--DTYTAH------------------------------------ 155
ABL             RLMT-G--DTYTAH------------------------------------ 155
ARG             RLMT-G--DTYTAH------------------------------------ 155
BRK             RLIK-E--DVYLSH------------------------------------ 155
SRM             RLLK-D--DIYSPS------------------------------------ 154
FRK             RVFKVDNEDIYESR------------------------------------ 157
FGR             RLIK-DDE--YNPC------------------------------------ 153
FYN             RLIE-DNE--YTAR------------------------------------ 153
SRC             RLIE-DNE--YTAR------------------------------------ 153
YES             RLIE-DNE--YTAR------------------------------------ 153
HCK             RVIE-DNE--YTAR------------------------------------ 153
LYN             RVIE-DNE--YTAR------------------------------------ 154
3LCK            RLIE-DNE--YTAR------------------------------------ 153
LCK             RLIE-DNE--YTAR------------------------------------ 153
BLK             RII--DSE--YTAQ------------------------------------ 152
FER             RQED-G--GVYSSS------------------------------------ 155
FES             REEA-D--GVYAAS------------------------------------ 156
SYK             KALRADENYYKAQ------------------------------------- 159
ZAP70           KALGADDSYYTAR------------------------------------- 159
FGFR1           RDIHHIDYYK--KT------------------------------------ 180
FGFR2           RDINNIDYYK--KT------------------------------------ 180
FGFR3           RDVHNLDYYK--KT------------------------------------ 180
FGFR4           RGVHHIDYYK--KT------------------------------------ 180
RET             RDVYEEDSYV--KR------------------------------------ 185
TIE1            RG---EEVYV--KK------------------------------------ 172
1FVRA           RG---QEVYV--KK------------------------------------ 172
TIE2            RG---QEVYV--KK------------------------------------ 172
FLT1            RDIYKNPDYV--RK------------------------------------ 230
KDR             RDIYKDPDYV--RK------------------------------------ 229
KDR_AVE         -DIYKDPDYV--RK------------------------------------ 169
FLT4            RDIYKDPDYV--RK------------------------------------ 227
FMS             RDIMNDSNYI--VK------------------------------------ 231
FLT3            RDIMSDSNYV--VR------------------------------------ 236
KIT             RDIKNDSNYV--VK------------------------------------ 238
PDGFRA          RDIMHDSNYV--SK------------------------------------ 260
PDGFRB          RDIMRDSNYI--SK------------------------------------ 261
MER             KKIYSGDYYR--QG------------------------------------ 171
AXL             KKIYNGDYYR--QG------------------------------------ 171
TYRO3           RKIYSGDYYR--QG------------------------------------ 172
MET             RDMYDKEYYSVHNK------------------------------------ 163
RON             RDILDREYYSVQQH------------------------------------ 163
HH498           RFLQSLDEDN---------------------------------------- 158
LZK             KELSD-----KST------------------------------------- 142
DLK             KELSD-----KST------------------------------------- 142
MLK1            REWH------RTT------------------------------------- 162
MLK3            REWH------KTT------------------------------------- 162
MLK2            REWH------KTT------------------------------------- 162
MLK4            REWH------RTT------------------------------------- 177
ZAK             RFHN------HTT------------------------------------- 147
TAK1            CDIQTHM------------------------------------------- 151
KSR1            GISGVVREGRREN------------------------------------- 155
KSR2            SISGVLQAGRRED------------------------------------- 155
ARAF            TVKTRWS---GAQ------------------------------------- 152
RAF1            TVKSRWS---GSQ------------------------------------- 152
BRAF            TVKSRWS---GSH------------------------------------- 152
LRRK2           QYCCRMGI------------------------------------------ 151
ANKRD3          KCNGLSHSHD--L------------------------------------- 155
SGK288          KWMEQSTRMQYIE------------------------------------- 156
RIPK2           KWRMMSLSQSRSS------------------------------------- 164
RIPK3           TFQGGSQSGT--G------------------------------------- 155
MLKL            KTQTSMSLGTTRE------------------------------------- 159
ANPA            SFRDLDPEQG---------------------------------------- 158
ANPB            SFRSTAEPDD---------------------------------------- 158
CYGD            RLLEAQKVLP---------------------------------------- 166
CYGF            DILEMLRLSE---------------------------------------- 171
TBCK            HMTAHGDDVDF--------------------------------------- 132
ERK1            RIADP--EHDH-TG------------------------------------ 158
3ERK            RVADP--DHDH-TG------------------------------------ 158
ERK2            RVADP--DHDH-TG------------------------------------ 158
ERK5            RGLCT-SPAEH-QY------------------------------------ 162
1JNK            -------SF----------------------------------------- 150
1PMNA           RTAGT--SF----------------------------------------- 155
JNK3            RTAGT--SF----------------------------------------- 155
JNK1            RTAGT--SF----------------------------------------- 155
JNK2            RTACT--NF----------------------------------------- 155
1P38            RHTDD--E------------------------------------------ 155
P38A            RHTDD--E------------------------------------------ 155
P38B            RQADE--E------------------------------------------ 163
P38D            RHADA--E------------------------------------------ 154
P38G            RQADS--E------------------------------------------ 155
NLK             RVEEL--DE---SR------------------------------------ 158
ERK7            RSLGDLPEGPE-DQ------------------------------------ 179
ERK3            RIMDP--HYSH-KG------------------------------------ 167
ERK4            RIVDQ--HYSH-KG------------------------------------ 164
ICK             REIRS-K-PP---------------------------------------- 152
MAK             RELRS-Q-PP---------------------------------------- 152
PCTAIRE1        RAKSI-PT--KT-------------------------------------- 153
PCTAIRE2        RAKSV-PT--KT-------------------------------------- 153
PCTAIRE3        RAKSV-PT--KT-------------------------------------- 153
PFTAIRE1        RAKSV-PS--HT-------------------------------------- 153
PFTAIRE2        RAKSI-PS--QT-------------------------------------- 153
CDC2            RAFGI-PI--RV-------------------------------------- 156
1HCL            RAFGV-PV--RT-------------------------------------- 151
CDK2            RAFGV-PV--RT-------------------------------------- 155
CDK3            RAFGV-PL--RT-------------------------------------- 155
CDK5            RAFGI-PV--RC-------------------------------------- 154
CDK7            KSFGS-PN--RA-------------------------------------- 157
CDK4            RIYSY-QM------------------------------------------ 164
1BLXA           RIYSF-QM------------------------------------------ 162
CDK6            RIYSF-QM------------------------------------------ 162
PITSLRE         REYGS-PL--KA-------------------------------------- 156
CDK10           RAYGV-PV--KP-------------------------------------- 156
CDK9            RAFSL-AKNSQ-PN------------------------------------ 165
CHED            RLYSS-E-ESRP-------------------------------------- 165
CRK7            RLYNS-E-ESRP-------------------------------------- 165
CCRK            RVFSP-D-GSRL-------------------------------------- 156
CDK11           RLFNS-PL--KPLA------------------------------------ 169
CDK8            RLFNS-PL--KPLA------------------------------------ 169
IKKA            KDV---DQG----------------------------------------- 161
IKKB            KEL---DQG----------------------------------------- 162
1PHK            CQL---DPG----------------------------------------- 159
PHKG1           CQL---EPG----------------------------------------- 159
PHKG2           CHL---EPG----------------------------------------- 158
CAMK2A          IEV--EGEQ----------------------------------------- 155
CAMK2B          IEV--QGDQ----------------------------------------- 155
CAMK2G          IEV--QGEQ----------------------------------------- 155
CAMK2D          IEV--QGDQ----------------------------------------- 155
CASK            IQL--GESG----------------------------------------- 162
1IA8A           TVFRYNNRE----------------------------------------- 150
CHK1            TVFRYNNRE----------------------------------------- 153
CLK1            TYD-----D----------------------------------------- 173
CLK4            TYD-----D----------------------------------------- 172
CLK2            TFD-----H----------------------------------------- 173
CLK3            TFD-----H----------------------------------------- 173
MAP2K5          TQLVNSIAKTY--------------------------------------- 151
MAP2K3          GYLVDSVAKTMD-------------------------------------- 161
MAP2K6          GYLVDSVAKTID-------------------------------------- 161
MAP2K4          GQLVDSIAKTRD-------------------------------------- 162
MAP2K7          GRLVDSKAKTRS-------------------------------------- 158
MAP2K1          GQLIDSMANSF--------------------------------------- 156
MAP2K2          GQLIDSMANSF--------------------------------------- 156
CDKL5           RNLSEGNNAN---------------------------------------- 155
CDKL1           RLLTGPSDY----------------------------------------- 154
CDKL4           QILI-PGDA----------------------------------------- 153
CDKL2           RTLAAPGEV----------------------------------------- 154
CDKL3           RTLAAPGDI----------------------------------------- 153
1I09B           KQLVR-GEP----------------------------------------- 157
GSK3B           KQLVR-GEP----------------------------------------- 157
1J1BA           KQLVR-GEP----------------------------------------- 157
GSK3A           KQLVR-GEP----------------------------------------- 157
LATS1           TGFRWTHDSKYYQSGDHPRQDSMDFSNEWGD------------------- 177
LATS2           TGFRWTHNSKYYQKGSHVRQDSMEPSDLWDD------------------- 177
NDR1            TGLKKAHRTEFYRNLNHSLP-----SDFTFQ------------------- 172
NDR2            TGLKKAHRTEFYRNLTHNPP-----SDFSFQ------------------- 172
MAST1           KMGLMSLTTNLYEG--HIEKDAREF------------------------- 169
MAST4           KVGLMSMTTNLYEG--HIEKDAREF------------------------- 169
MAST2           KIGLMSLTTNLYEG--HIEKDAREF------------------------- 169
MAST3           KIGLMSMATNLYEG--HIEKDAREF------------------------- 169
MRCKA           LKLME---------------------DGTVQ------------------- 157
MRCKB           LKMND---------------------DGTVQ------------------- 157
DMPK2           LRLNT---------------------NGMVD------------------- 157
DMPK1           LKLRA---------------------DGTVR------------------- 157
ROCK1           MKMNK---------------------EGMVR------------------- 155
ROCK2           MKMDE---------------------TGMVH------------------- 155
CRIK            AKMNS---------------------NKMVN------------------- 157
MASTL           -KVTL---------------------NRDIN------------------- 153
1O6LA           KEGISDG-A----------------------------------------- 154
AKT2            KEGISDG-A----------------------------------------- 154
AKT1            KEGIKDG-A----------------------------------------- 155
AKT3            KEGITDA-A----------------------------------------- 154
MSK1            KEFVADETE----------------------------------------- 160
MSK2            KEFLTEEKE----------------------------------------- 160
P70S6K          KESIHDG-T----------------------------------------- 158
P70S6KB         KESIHEG-A----------------------------------------- 158
RSK1            KEAIDHD-K----------------------------------------- 156
RSK3            KEAIDHE-K----------------------------------------- 156
RSK2            KESIDHE-K----------------------------------------- 156
RSK4            KESVDQE-K----------------------------------------- 156
1FOTA           KY---VP-D----------------------------------------- 151
1CDKA           KRV---K-G----------------------------------------- 151
PKACA           KRV---K-G----------------------------------------- 151
PKACB           KRV---K-G----------------------------------------- 151
PKACG           KRV---K-G----------------------------------------- 151
PRKX            KKLV----D----------------------------------------- 151
PRKY            KKLV----D----------------------------------------- 151
PKCA            KEHMMDG-V----------------------------------------- 155
PKCB            KENIWDG-V----------------------------------------- 155
PKCG            KENVFPG-T----------------------------------------- 160
PKCE            KEGILNG-V----------------------------------------- 155
PKCH            KEGICNG-V----------------------------------------- 155
PKCD            KENIFGE-S----------------------------------------- 155
PKCT            KENMLGD-A----------------------------------------- 155
PKCI            KEGLRPG-D----------------------------------------- 155
PKCZ            KEGLGPG-D----------------------------------------- 155
PKN1            KEGMGYG-D----------------------------------------- 156
PKN2            KEGMGYG-D----------------------------------------- 156
PKN3            KEGIGFG-D----------------------------------------- 156
SGK             KENIEHN-S----------------------------------------- 155
SGK2            KEGVEPE-D----------------------------------------- 155
SGK3            KEGIAIS-D----------------------------------------- 155
PKG1            KK-IGFG-K----------------------------------------- 154
PKG2            KK-IGSG-Q----------------------------------------- 153
AURB            VH--APSL------------------------------------------ 152
AURC            VHTPLP-------------------------------------------- 152
AURA            VH--APSS------------------------------------------ 152
AURORA2_AVE     VH------------------------------------------------ 148
PLK1            TKVEYDGE------------------------------------------ 154
PLK2            ARLEPLEH------------------------------------------ 154
PLK3            ARLEPPEQ------------------------------------------ 154
PLK4            TQLKMPHE------------------------------------------ 155
NEK11           RLLMGSCD------------------------------------------ 159
YANK1           AMLPRETQ------------------------------------------ 154
YANK2           TVVKGAER------------------------------------------ 154
YANK3           TIIKDGER------------------------------------------ 154
SGK494          RHVPQGAQ------------------------------------------ 153
DOMAIN2_MSK1    RLKPPD-------NQP---------------------------------- 153
DOMAIN2_MSK2    RLRPQSPG------VP---------------------------------- 149
DOMAIN2_RSK1    KQLRAG-------NGL---------------------------------- 153
DOMAIN2_RSK2    KQLRAE-------NGL---------------------------------- 153
DOMAIN2_RSK3    KQLRAE-------NGL---------------------------------- 153
DOMAIN2_RSK4    KQLRGE-------NGL---------------------------------- 153
DRAK1           RILKNS--------EE---------------------------------- 159
DRAK2           RKIGHA--------CE---------------------------------- 159
1JKSA           HKIDFG--------NE---------------------------------- 161
DAPK1           HKIDFG--------NE---------------------------------- 161
DAPK3           HKIEAG--------NE---------------------------------- 161
DAPK2           HEIEDG--------VE---------------------------------- 161
SGK085          RRYKPR--------EK---------------------------------- 154
CAMLCK          RRYKPR--------EK---------------------------------- 154
SKMLCK          RRYNPN--------EK---------------------------------- 154
SMMLCK          RRLENA--------GS---------------------------------- 154
1KOBA           TKLNPD--------EI---------------------------------- 154
1TKIA           RQLKPG--------DN---------------------------------- 153
TTN             RQLKPG--------DN---------------------------------- 153
PKD1            RIIGEK--------SF---------------------------------- 157
PKD3            RIIGEK--------SF---------------------------------- 157
PKD2            RIIGEK--------SF---------------------------------- 157
PSKH1           SARKKGD------DCL---------------------------------- 156
PSKH2           YSGKKSG------DWT---------------------------------- 156
CAMK1A          KMEDPG--------SV---------------------------------- 155
CAMK1D          KMEGKG--------DV---------------------------------- 155
CAMK1B          KI-QAG--------NM---------------------------------- 154
CAMK1G          KM-EQN--------GI---------------------------------- 153
CAMK4           KIVEHQ--------VL---------------------------------- 152
DCAMKL1         TIVD----------GP---------------------------------- 154
DCAMKL2         TVVE----------GP---------------------------------- 154
DCAMKL3         KHVV----------RP---------------------------------- 154
CHK2            KILGET--------SL---------------------------------- 161
MAPKAPK2        KETTSH--------NS---------------------------------- 156
MAPKAPK3        KETTQ---------NA---------------------------------- 155
MAPKAPK5        KI----------DQGD---------------------------------- 158
MNK1            SGMKLNNSCTPITTPE---------------------------------- 164
MNK2            SGIKLNGDCSPISTPE---------------------------------- 163
VACAMKL         KL----------ENGL---------------------------------- 153
GCK             GELTA------SVA------------------------------------ 151
KHS1            AKITA------TIA------------------------------------ 151
KHS2            AQITA------TIA------------------------------------ 151
HPK1            AQIGA------TLA------------------------------------ 151
MST1            GQLTD------TMA------------------------------------ 150
MST2            GQLTD------TMA------------------------------------ 150
MST3            GQLTD------TQI------------------------------------ 151
YSK1            GQLTD------TQI------------------------------------ 151
MST4            GQLTD------TQI------------------------------------ 151
LOK             AKNLK------TLQ------------------------------------ 152
SLK             AKNTR------TIQ------------------------------------ 152
MAP3K4          VKLKNNAQTM--PG------------------------------------ 155
MAP3K2          KRLQTICLS---GT------------------------------------ 161
MAP3K3          KRLQTICMS---GT------------------------------------ 161
MAP3K8          RRLAWAGLNGTHSD------------------------------------ 162
MAP3K5          KRLAG------INP------------------------------------ 160
MAP3K7          KRLAG------VNP------------------------------------ 151
MAP3K6          KRLAG------ITP------------------------------------ 150
PAK1            AQITP------EQS------------------------------------ 150
PAK3            AQITP------EQS------------------------------------ 150
PAK2            AQITP------EQS------------------------------------ 151
PAK4            AQVSK------EVP------------------------------------ 150
PAK5            AQVSK------EVP------------------------------------ 150
PAK6            AQISK------DVP------------------------------------ 150
OSR1            AFLATGG-DITRNK------------------------------------ 165
STLK3           AFLATGG-DVTRNK------------------------------------ 165
TAO1            SMASP------A-------------------------------------- 152
TAO3            SMASP------A-------------------------------------- 152
TAO2            SIMAP--------------------------------------------- 151
MYO3A           AQLTS------TRH------------------------------------ 160
MYO3B           AQLTS------TRL------------------------------------ 160
ZC1/HGK         AQLDR------TVG------------------------------------ 159
ZC3/MINK        AQLDR------TVG------------------------------------ 159
ZC2/TNIK        AQLDR------TVG------------------------------------ 159
ZC4/NRK         AQVSR------TNG------------------------------------ 183
MAP3K1          ARLASKGT--GAGE------------------------------------ 162
GAK             T---TISHY------PDYSWS----------------------------- 168
SGK495          K--HLVSEGD---------------------------------------- 71
TRB1            H--IMKGEDD---------------------------------------- 139
TRB2            Y--ILRGDDD---------------------------------------- 144
TRB3            C--VLTGPDD---------------------------------------- 142
SSTK            R---QAHGY----------------------------------------- 153
TSSK3           K---VLPKS----------------------------------------- 152
TSSK1           K---RCLRDD---------------------------------------- 154
TSSK2           K---RCLRDS---------------------------------------- 154
TSSK4           K---MVPSNQPVGCSPSYRQV----------------------------- 164
HUNK            NCAGILGYSD---------------------------------------- 158
SNRK            N---KFQPGK---------------------------------------- 154
NIM1            T---VSKKGE---------------------------------------- 152
MELK            A---KPKGNK---------------------------------------- 151
BRSK1           S---LQVGDS---------------------------------------- 152
BRSK2           S---LQVGDS---------------------------------------- 152
MARK1           N---EFTVGN---------------------------------------- 152
MARK2           N---EFTFGN---------------------------------------- 152
MARK3           N---EFTVGG---------------------------------------- 152
MARK4           N---EFTLGS---------------------------------------- 152
QIK             N---FFKSGE---------------------------------------- 152
SIK             N---FYKSGE---------------------------------------- 152
QSK             N---LFTPGQ---------------------------------------- 152
AMPKA1          N---MMSDGE---------------------------------------- 153
AMPKA2          N---MMSDGE---------------------------------------- 153
NUAK1           N---LYQKDK---------------------------------------- 153
NUAK2           N---LYHQGK---------------------------------------- 152
BIKE            TNKF---LN------PQKDGV----------------------------- 164
AAK1            TNK---FQN------PQTEGV----------------------------- 165
LIMK1           RLMVD--------------EK----------------------------- 151
LIMK2           RLIVE--------------ER----------------------------- 150
TESK1           EKIPV--------------YR----------------------------- 151
TESK2           EKIPD--------------VS----------------------------- 131
WNK1            TLKR----------------A----------------------------- 157
WNK3            TLMR----------------T----------------------------- 157
WNK2            TLKR----------------A----------------------------- 157
WNK4            TLKR----------------A----------------------------- 157
NEK10           KQKQE---------------N----------------------------- 165
NEK6            RFFSS--------------ET----------------------------- 157
NEK7            RFFSS--------------KT----------------------------- 157
NEK2            RILNH--------------DT----------------------------- 163
NEK1            RVLNS--------------TV----------------------------- 154
NEK5            RVLNN--------------SM----------------------------- 155
NEK3            RLLSN--------------PM----------------------------- 153
NEK4            RVLEN--------------HC----------------------------- 155
NEK8            KILSS--------------K------------------------------ 154
NEK9            KKLNS--------------EY----------------------------- 154
NRBP1           --------------DTINNHV----------------------------- 166
NRBP2           RIFSNALRPPTALPDDLRSPI----------------------------- 180
CLIK1           KVCAGLAPRGKEGNQDNKNVN----------------------------- 205
CLIK1L          KVCSA------SGQNPEEPVS----------------------------- 202
STK33           V----------------KKQS----------------------------- 159
DOMAIN2_GCN2    KRLADI----CKE--------DVF-------------------------- 180
SCYL1           YSAQGN----GGGPPR-KGIP----------------------------- 151
SCYL3           CKVSQA----TPEFLRSIQ--SIR-------------------------- 140
DOMAIN2_JAK1    ITVLSRQ-----------ECI----------------------------- 171
DOMAIN2_TYK2    LGALSRE-----------ERV----------------------------- 185
DOMAIN2_JAK2    ITVLPKD-----------ILQ----------------------------- 169
DOMAIN2_JAK3    PAVLSLE-----------MLT----------------------------- 165
ILK             -----------KFSFQCPG--RMY-------------------------- 159
LRRK1           RQSFHEG---------ALGVE----------------------------- 184
PBK             LPLDEN----MTVTDPEACYI----------------------------- 176
WEE1            TRISSPQ-----------VEE----------------------------- 179
WEE1B           TSINKPK-----------VEE----------------------------- 183
SGK071          VLMTDK----AKWNIRAEE--DPF-------------------------- 170
PIK3R4          KPTYLPEDNPADFNYFFDTSRRR--------------------------- 168
MSSK1           -------------------------------------------------- 297
SRPK1           -------------------------------------------------- 418
SRPK2           -------------------------------------------------- 450
RSKL1           SEVEDS----------CDS--DAI-------------------------- 142
RSKL2           SEVEPQ----------CCG--EAV-------------------------- 294
SGK396          KSVSQR----ASVNMMV--------------------------------- 157
VRK1            Y------------------------------------------------- 166
VRK2            Y------------------------------------------------- 163
VRK3            F------------------------------------------------- 111
BUB1            IDMKLF----PKGTIFTAKC------------------------------ 180
BUBR1           VDLRVQL--------------DVF-------------------------- 173
SGK196          PLVNHS----SGMLVKCGH--REL-------------------------- 169
SGK493          RVEETP----CAGSTDCIL------------------------------- 174
                                                                  

DYRK1A          -------------------------------------------------- 160
DYRK1B          -------------------------------------------------- 160
DYRK2           -------------------------------------------------- 158
DYRK3           -------------------------------------------------- 158
DYRK4           -------------------------------------------------- 158
HIPK1           -------------------------------------------------- 160
HIPK2           -------------------------------------------------- 160
HIPK3           -------------------------------------------------- 160
HIPK4           -------------------------------------------------- 163
PRP4            -------------------------------------------------- 160
MOK             -------------------------------------------------- 155
1A6O            -------------------------------------------------- 150
1LPUA           -------------------------------------------------- 150
CK2A1           -------------------------------------------------- 150
CK2A1-RS        -------------------------------------------------- 150
CK2A2           -------------------------------------------------- 150
HSER            -------------------------------------------------- 156
SLOB            -------------------------------------------------- 171
CDC7            TTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISH 243
1CSN            -------------------------------------------------- 163
CK1G1           -------------------------------------------------- 164
CK1G3           -------------------------------------------------- 163
CK1G2           -------------------------------------------------- 163
CK1A            -------------------------------------------------- 161
CK1A2           -------------------------------------------------- 161
1CKJA           -------------------------------------------------- 161
CK1D            -------------------------------------------------- 161
CK1E            -------------------------------------------------- 161
TTBK1           -------------------------------------------------- 162
TTBK2           -------------------------------------------------- 162
TLK1            -------------------------------------------------- 171
TLK2            -------------------------------------------------- 172
GPRK4           -------------------------------------------------- 157
GPRK6           -------------------------------------------------- 157
GPRK5           -------------------------------------------------- 157
RHOK            -------------------------------------------------- 160
GPRK7           -------------------------------------------------- 157
BARK1           -------------------------------------------------- 157
BARK2           -------------------------------------------------- 157
TTK             -------------------------------------------------- 156
RIPK1           -------------------------------------------------- 162
HASPIN          -------------------------------------------------- 228
GCN2            -------------------------------------------------- 303
HRI             -------------------------------------------------- 317
KIS             -------------------------------------------------- 172
PDK1            -------------------------------------------------- 155
PKR             -------------------------------------------------- 175
PEK             -------------------------------------------------- 383
PRPK            -------------------------------------------------- 164
DOMAIN2_OBSCN   -------------------------------------------------- 139
DOMAIN2_SPEG    -------------------------------------------------- 139
LMR1            -------------------------------------------------- 148
LMR2            -------------------------------------------------- 148
LMR3            -------------------------------------------------- 153
SGK307          -------------------------------------------------- 58
STLK5           -------------------------------------------------- 146
STLK6           -------------------------------------------------- 146
STLK6-RS        -------------------------------------------------- 146
OBSCN           -------------------------------------------------- 141
SPEG            -------------------------------------------------- 142
TRAD            -------------------------------------------------- 142
TRIO            -------------------------------------------------- 142
SGK223          -------------------------------------------------- 170
SGK269          -------------------------------------------------- 145
ALK1            -------------------------------------------------- 163
ALK2            -------------------------------------------------- 163
IRAK4           -------------------------------------------------- 158
BMPR2           -------------------------------------------------- 169
TGFBR2          -------------------------------------------------- 170
ACTR2           -------------------------------------------------- 164
ACTR2B          -------------------------------------------------- 165
1B6CB           -------------------------------------------------- 163
TGFBR1          -------------------------------------------------- 163
ALK4            -------------------------------------------------- 163
ALK7            -------------------------------------------------- 163
BMPR1A          -------------------------------------------------- 163
BMPR1B          -------------------------------------------------- 163
IRAK1           -------------------------------------------------- 168
IRAK2           -------------------------------------------------- 149
IRAK3           -------------------------------------------------- 152
MISR2           -------------------------------------------------- 154
MYT1            -------------------------------------------------- 147
SBK             -------------------------------------------------- 147
SGK110          -------------------------------------------------- 146
SGK069          -------------------------------------------------- 147
SGK496          -------------------------------------------------- 149
NIK             -------------------------------------------------- 140
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------- 161
IKKE            -------------------------------------------------- 159
TBK1            -------------------------------------------------- 159
MOS             -------------------------------------------------- 174
LKB1            -------------------------------------------------- 159
CAMKK1          -------------------------------------------------- 185
CAMKK2          -------------------------------------------------- 177
PASK            -------------------------------------------------- 158
PIM1            -------------------------------------------------- 158
PIM3            -------------------------------------------------- 159
PIM2            -------------------------------------------------- 160
COT             -------------------------------------------------- 149
SCYL2           -------------------------------------------------- 188
FUSED           -------------------------------------------------- 154
ULK1            -------------------------------------------------- 160
ULK2            -------------------------------------------------- 160
ULK3            -------------------------------------------------- 154
ULK4            -------------------------------------------------- 134
IRE1            -------------------------------------------------- 153
IRE2            -------------------------------------------------- 153
RNASEL          -------------------------------------------------- 141
MPSK1           -------------------------------------------------- 165
PINK1           -------------------------------------------------- 243
ALK             -------------------------------------------------- 166
LTK             -------------------------------------------------- 166
ROS             -------------------------------------------------- 169
IGF1R           -------------------------------------------------- 166
1IR3A           -------------------------------------------------- 166
INSR            -------------------------------------------------- 166
IRR             -------------------------------------------------- 166
1M14A           -------------------------------------------------- 156
EGFR            -------------------------------------------------- 156
HER2/ERBB2      -------------------------------------------------- 156
HER4/ERBB4      -------------------------------------------------- 155
HER3/ERBB3      -------------------------------------------------- 155
ITK             -------------------------------------------------- 149
TEC             -------------------------------------------------- 148
TXK             -------------------------------------------------- 149
BMX             -------------------------------------------------- 149
1K2PA           -------------------------------------------------- 149
BTK             -------------------------------------------------- 149
CCK4            -------------------------------------------------- 164
ROR1            -------------------------------------------------- 172
ROR2            -------------------------------------------------- 172
MUSK            -------------------------------------------------- 180
TRKA            -------------------------------------------------- 170
TRKB            -------------------------------------------------- 168
TRKC            -------------------------------------------------- 171
DDR1            -------------------------------------------------- 186
DDR2            -------------------------------------------------- 177
RYK             -------------------------------------------------- 165
JAK1            -------------------------------------------------- 158
JAK2            -------------------------------------------------- 158
JAK3            -------------------------------------------------- 158
ACK             -------------------------------------------------- 157
TYK2            -------------------------------------------------- 157
TNK1            -------------------------------------------------- 160
EPHA1           -------------------------------------------------- 160
EPHA10          -------------------------------------------------- 159
FAK             -------------------------------------------------- 158
EPHB6           -------------------------------------------------- 149
EPHA2           -------------------------------------------------- 162
EPHA8           -------------------------------------------------- 161
EPHA6           -------------------------------------------------- 203
EPHB1           -------------------------------------------------- 162
EPHB2           -------------------------------------------------- 162
EPHB3           -------------------------------------------------- 162
EPHB4           -------------------------------------------------- 162
EPHA7           -------------------------------------------------- 161
EPHA4           -------------------------------------------------- 161
EPHA3           -------------------------------------------------- 161
EPHA5           -------------------------------------------------- 161
PYK2            -------------------------------------------------- 158
CSK             -------------------------------------------------- 149
CTK             -------------------------------------------------- 147
1IEPA           -------------------------------------------------- 155
ABL             -------------------------------------------------- 155
ARG             -------------------------------------------------- 155
BRK             -------------------------------------------------- 155
SRM             -------------------------------------------------- 154
FRK             -------------------------------------------------- 157
FGR             -------------------------------------------------- 153
FYN             -------------------------------------------------- 153
SRC             -------------------------------------------------- 153
YES             -------------------------------------------------- 153
HCK             -------------------------------------------------- 153
LYN             -------------------------------------------------- 154
3LCK            -------------------------------------------------- 153
LCK             -------------------------------------------------- 153
BLK             -------------------------------------------------- 152
FER             -------------------------------------------------- 155
FES             -------------------------------------------------- 156
SYK             -------------------------------------------------- 159
ZAP70           -------------------------------------------------- 159
FGFR1           -------------------------------------------------- 180
FGFR2           -------------------------------------------------- 180
FGFR3           -------------------------------------------------- 180
FGFR4           -------------------------------------------------- 180
RET             -------------------------------------------------- 185
TIE1            -------------------------------------------------- 172
1FVRA           -------------------------------------------------- 172
TIE2            -------------------------------------------------- 172
FLT1            -------------------------------------------------- 230
KDR             -------------------------------------------------- 229
KDR_AVE         -------------------------------------------------- 169
FLT4            -------------------------------------------------- 227
FMS             -------------------------------------------------- 231
FLT3            -------------------------------------------------- 236
KIT             -------------------------------------------------- 238
PDGFRA          -------------------------------------------------- 260
PDGFRB          -------------------------------------------------- 261
MER             -------------------------------------------------- 171
AXL             -------------------------------------------------- 171
TYRO3           -------------------------------------------------- 172
MET             -------------------------------------------------- 163
RON             -------------------------------------------------- 163
HH498           -------------------------------------------------- 158
LZK             -------------------------------------------------- 142
DLK             -------------------------------------------------- 142
MLK1            -------------------------------------------------- 162
MLK3            -------------------------------------------------- 162
MLK2            -------------------------------------------------- 162
MLK4            -------------------------------------------------- 177
ZAK             -------------------------------------------------- 147
TAK1            -------------------------------------------------- 151
KSR1            -------------------------------------------------- 155
KSR2            -------------------------------------------------- 155
ARAF            -------------------------------------------------- 152
RAF1            -------------------------------------------------- 152
BRAF            -------------------------------------------------- 152
LRRK2           -------------------------------------------------- 151
ANKRD3          -------------------------------------------------- 155
SGK288          -------------------------------------------------- 156
RIPK2           -------------------------------------------------- 164
RIPK3           -------------------------------------------------- 155
MLKL            -------------------------------------------------- 159
ANPA            -------------------------------------------------- 158
ANPB            -------------------------------------------------- 158
CYGD            -------------------------------------------------- 166
CYGF            -------------------------------------------------- 171
TBCK            -------------------------------------------------- 132
ERK1            -------------------------------------------------- 158
3ERK            -------------------------------------------------- 158
ERK2            -------------------------------------------------- 158
ERK5            -------------------------------------------------- 162
1JNK            -------------------------------------------------- 150
1PMNA           -------------------------------------------------- 155
JNK3            -------------------------------------------------- 155
JNK1            -------------------------------------------------- 155
JNK2            -------------------------------------------------- 155
1P38            -------------------------------------------------- 155
P38A            -------------------------------------------------- 155
P38B            -------------------------------------------------- 163
P38D            -------------------------------------------------- 154
P38G            -------------------------------------------------- 155
NLK             -------------------------------------------------- 158
ERK7            -------------------------------------------------- 179
ERK3            -------------------------------------------------- 167
ERK4            -------------------------------------------------- 164
ICK             -------------------------------------------------- 152
MAK             -------------------------------------------------- 152
PCTAIRE1        -------------------------------------------------- 153
PCTAIRE2        -------------------------------------------------- 153
PCTAIRE3        -------------------------------------------------- 153
PFTAIRE1        -------------------------------------------------- 153
PFTAIRE2        -------------------------------------------------- 153
CDC2            -------------------------------------------------- 156
1HCL            -------------------------------------------------- 151
CDK2            -------------------------------------------------- 155
CDK3            -------------------------------------------------- 155
CDK5            -------------------------------------------------- 154
CDK7            -------------------------------------------------- 157
CDK4            -------------------------------------------------- 164
1BLXA           -------------------------------------------------- 162
CDK6            -------------------------------------------------- 162
PITSLRE         -------------------------------------------------- 156
CDK10           -------------------------------------------------- 156
CDK9            -------------------------------------------------- 165
CHED            -------------------------------------------------- 165
CRK7            -------------------------------------------------- 165
CCRK            -------------------------------------------------- 156
CDK11           -------------------------------------------------- 169
CDK8            -------------------------------------------------- 169
IKKA            -------------------------------------------------- 161
IKKB            -------------------------------------------------- 162
1PHK            -------------------------------------------------- 159
PHKG1           -------------------------------------------------- 159
PHKG2           -------------------------------------------------- 158
CAMK2A          -------------------------------------------------- 155
CAMK2B          -------------------------------------------------- 155
CAMK2G          -------------------------------------------------- 155
CAMK2D          -------------------------------------------------- 155
CASK            -------------------------------------------------- 162
1IA8A           -------------------------------------------------- 150
CHK1            -------------------------------------------------- 153
CLK1            -------------------------------------------------- 173
CLK4            -------------------------------------------------- 172
CLK2            -------------------------------------------------- 173
CLK3            -------------------------------------------------- 173
MAP2K5          -------------------------------------------------- 151
MAP2K3          -------------------------------------------------- 161
MAP2K6          -------------------------------------------------- 161
MAP2K4          -------------------------------------------------- 162
MAP2K7          -------------------------------------------------- 158
MAP2K1          -------------------------------------------------- 156
MAP2K2          -------------------------------------------------- 156
CDKL5           -------------------------------------------------- 155
CDKL1           -------------------------------------------------- 154
CDKL4           -------------------------------------------------- 153
CDKL2           -------------------------------------------------- 154
CDKL3           -------------------------------------------------- 153
1I09B           -------------------------------------------------- 157
GSK3B           -------------------------------------------------- 157
1J1BA           -------------------------------------------------- 157
GSK3A           -------------------------------------------------- 157
LATS1           -------------------------------------------------- 177
LATS2           -------------------------------------------------- 177
NDR1            -------------------------------------------------- 172
NDR2            -------------------------------------------------- 172
MAST1           -------------------------------------------------- 169
MAST4           -------------------------------------------------- 169
MAST2           -------------------------------------------------- 169
MAST3           -------------------------------------------------- 169
MRCKA           -------------------------------------------------- 157
MRCKB           -------------------------------------------------- 157
DMPK2           -------------------------------------------------- 157
DMPK1           -------------------------------------------------- 157
ROCK1           -------------------------------------------------- 155
ROCK2           -------------------------------------------------- 155
CRIK            -------------------------------------------------- 157
MASTL           -------------------------------------------------- 153
1O6LA           -------------------------------------------------- 154
AKT2            -------------------------------------------------- 154
AKT1            -------------------------------------------------- 155
AKT3            -------------------------------------------------- 154
MSK1            -------------------------------------------------- 160
MSK2            -------------------------------------------------- 160
P70S6K          -------------------------------------------------- 158
P70S6KB         -------------------------------------------------- 158
RSK1            -------------------------------------------------- 156
RSK3            -------------------------------------------------- 156
RSK2            -------------------------------------------------- 156
RSK4            -------------------------------------------------- 156
1FOTA           -------------------------------------------------- 151
1CDKA           -------------------------------------------------- 151
PKACA           -------------------------------------------------- 151
PKACB           -------------------------------------------------- 151
PKACG           -------------------------------------------------- 151
PRKX            -------------------------------------------------- 151
PRKY            -------------------------------------------------- 151
PKCA            -------------------------------------------------- 155
PKCB            -------------------------------------------------- 155
PKCG            -------------------------------------------------- 160
PKCE            -------------------------------------------------- 155
PKCH            -------------------------------------------------- 155
PKCD            -------------------------------------------------- 155
PKCT            -------------------------------------------------- 155
PKCI            -------------------------------------------------- 155
PKCZ            -------------------------------------------------- 155
PKN1            -------------------------------------------------- 156
PKN2            -------------------------------------------------- 156
PKN3            -------------------------------------------------- 156
SGK             -------------------------------------------------- 155
SGK2            -------------------------------------------------- 155
SGK3            -------------------------------------------------- 155
PKG1            -------------------------------------------------- 154
PKG2            -------------------------------------------------- 153
AURB            -------------------------------------------------- 152
AURC            -------------------------------------------------- 152
AURA            -------------------------------------------------- 152
AURORA2_AVE     -------------------------------------------------- 148
PLK1            -------------------------------------------------- 154
PLK2            -------------------------------------------------- 154
PLK3            -------------------------------------------------- 154
PLK4            -------------------------------------------------- 155
NEK11           -------------------------------------------------- 159
YANK1           -------------------------------------------------- 154
YANK2           -------------------------------------------------- 154
YANK3           -------------------------------------------------- 154
SGK494          -------------------------------------------------- 153
DOMAIN2_MSK1    -------------------------------------------------- 153
DOMAIN2_MSK2    -------------------------------------------------- 149
DOMAIN2_RSK1    -------------------------------------------------- 153
DOMAIN2_RSK2    -------------------------------------------------- 153
DOMAIN2_RSK3    -------------------------------------------------- 153
DOMAIN2_RSK4    -------------------------------------------------- 153
DRAK1           -------------------------------------------------- 159
DRAK2           -------------------------------------------------- 159
1JKSA           -------------------------------------------------- 161
DAPK1           -------------------------------------------------- 161
DAPK3           -------------------------------------------------- 161
DAPK2           -------------------------------------------------- 161
SGK085          -------------------------------------------------- 154
CAMLCK          -------------------------------------------------- 154
SKMLCK          -------------------------------------------------- 154
SMMLCK          -------------------------------------------------- 154
1KOBA           -------------------------------------------------- 154
1TKIA           -------------------------------------------------- 153
TTN             -------------------------------------------------- 153
PKD1            -------------------------------------------------- 157
PKD3            -------------------------------------------------- 157
PKD2            -------------------------------------------------- 157
PSKH1           -------------------------------------------------- 156
PSKH2           -------------------------------------------------- 156
CAMK1A          -------------------------------------------------- 155
CAMK1D          -------------------------------------------------- 155
CAMK1B          -------------------------------------------------- 154
CAMK1G          -------------------------------------------------- 153
CAMK4           -------------------------------------------------- 152
DCAMKL1         -------------------------------------------------- 154
DCAMKL2         -------------------------------------------------- 154
DCAMKL3         -------------------------------------------------- 154
CHK2            -------------------------------------------------- 161
MAPKAPK2        -------------------------------------------------- 156
MAPKAPK3        -------------------------------------------------- 155
MAPKAPK5        -------------------------------------------------- 158
MNK1            -------------------------------------------------- 164
MNK2            -------------------------------------------------- 163
VACAMKL         -------------------------------------------------- 153
GCK             -------------------------------------------------- 151
KHS1            -------------------------------------------------- 151
KHS2            -------------------------------------------------- 151
HPK1            -------------------------------------------------- 151
MST1            -------------------------------------------------- 150
MST2            -------------------------------------------------- 150
MST3            -------------------------------------------------- 151
YSK1            -------------------------------------------------- 151
MST4            -------------------------------------------------- 151
LOK             -------------------------------------------------- 152
SLK             -------------------------------------------------- 152
MAP3K4          -------------------------------------------------- 155
MAP3K2          -------------------------------------------------- 161
MAP3K3          -------------------------------------------------- 161
MAP3K8          -------------------------------------------------- 162
MAP3K5          -------------------------------------------------- 160
MAP3K7          -------------------------------------------------- 151
MAP3K6          -------------------------------------------------- 150
PAK1            -------------------------------------------------- 150
PAK3            -------------------------------------------------- 150
PAK2            -------------------------------------------------- 151
PAK4            -------------------------------------------------- 150
PAK5            -------------------------------------------------- 150
PAK6            -------------------------------------------------- 150
OSR1            -------------------------------------------------- 165
STLK3           -------------------------------------------------- 165
TAO1            -------------------------------------------------- 152
TAO3            -------------------------------------------------- 152
TAO2            -------------------------------------------------- 151
MYO3A           -------------------------------------------------- 160
MYO3B           -------------------------------------------------- 160
ZC1/HGK         -------------------------------------------------- 159
ZC3/MINK        -------------------------------------------------- 159
ZC2/TNIK        -------------------------------------------------- 159
ZC4/NRK         -------------------------------------------------- 183
MAP3K1          -------------------------------------------------- 162
GAK             -------------------------------------------------- 168
SGK495          -------------------------------------------------- 71
TRB1            -------------------------------------------------- 139
TRB2            -------------------------------------------------- 144
TRB3            -------------------------------------------------- 142
SSTK            -------------------------------------------------- 153
TSSK3           -------------------------------------------------- 152
TSSK1           -------------------------------------------------- 154
TSSK2           -------------------------------------------------- 154
TSSK4           -------------------------------------------------- 164
HUNK            -------------------------------------------------- 158
SNRK            -------------------------------------------------- 154
NIM1            -------------------------------------------------- 152
MELK            -------------------------------------------------- 151
BRSK1           -------------------------------------------------- 152
BRSK2           -------------------------------------------------- 152
MARK1           -------------------------------------------------- 152
MARK2           -------------------------------------------------- 152
MARK3           -------------------------------------------------- 152
MARK4           -------------------------------------------------- 152
QIK             -------------------------------------------------- 152
SIK             -------------------------------------------------- 152
QSK             -------------------------------------------------- 152
AMPKA1          -------------------------------------------------- 153
AMPKA2          -------------------------------------------------- 153
NUAK1           -------------------------------------------------- 153
NUAK2           -------------------------------------------------- 152
BIKE            -------------------------------------------------- 164
AAK1            -------------------------------------------------- 165
LIMK1           -------------------------------------------------- 151
LIMK2           -------------------------------------------------- 150
TESK1           -------------------------------------------------- 151
TESK2           -------------------------------------------------- 131
WNK1            -------------------------------------------------- 157
WNK3            -------------------------------------------------- 157
WNK2            -------------------------------------------------- 157
WNK4            -------------------------------------------------- 157
NEK10           -------------------------------------------------- 165
NEK6            -------------------------------------------------- 157
NEK7            -------------------------------------------------- 157
NEK2            -------------------------------------------------- 163
NEK1            -------------------------------------------------- 154
NEK5            -------------------------------------------------- 155
NEK3            -------------------------------------------------- 153
NEK4            -------------------------------------------------- 155
NEK8            -------------------------------------------------- 154
NEK9            -------------------------------------------------- 154
NRBP1           -------------------------------------------------- 166
NRBP2           -------------------------------------------------- 180
CLIK1           -------------------------------------------------- 205
CLIK1L          -------------------------------------------------- 202
STK33           -------------------------------------------------- 159
DOMAIN2_GCN2    -------------------------------------------------- 180
SCYL1           -------------------------------------------------- 151
SCYL3           -------------------------------------------------- 140
DOMAIN2_JAK1    -------------------------------------------------- 171
DOMAIN2_TYK2    -------------------------------------------------- 185
DOMAIN2_JAK2    -------------------------------------------------- 169
DOMAIN2_JAK3    -------------------------------------------------- 165
ILK             -------------------------------------------------- 159
LRRK1           -------------------------------------------------- 184
PBK             -------------------------------------------------- 176
WEE1            -------------------------------------------------- 179
WEE1B           -------------------------------------------------- 183
SGK071          -------------------------------------------------- 170
PIK3R4          -------------------------------------------------- 168
MSSK1           -------------------------------------------------- 297
SRPK1           -------------------------------------------------- 418
SRPK2           -------------------------------------------------- 450
RSKL1           -------------------------------------------------- 142
RSKL2           -------------------------------------------------- 294
SGK396          -------------------------------------------------- 157
VRK1            -------------------------------------------------- 166
VRK2            -------------------------------------------------- 163
VRK3            -------------------------------------------------- 111
BUB1            -------------------------------------------------- 180
BUBR1           -------------------------------------------------- 173
SGK196          -------------------------------------------------- 169
SGK493          -------------------------------------------------- 174
                                                                  

DYRK1A          -------------------------------------------------- 160
DYRK1B          -------------------------------------------------- 160
DYRK2           -------------------------------------------------- 158
DYRK3           -------------------------------------------------- 158
DYRK4           -------------------------------------------------- 158
HIPK1           -------------------------------------------------- 160
HIPK2           -------------------------------------------------- 160
HIPK3           -------------------------------------------------- 160
HIPK4           -------------------------------------------------- 163
PRP4            -------------------------------------------------- 160
MOK             -------------------------------------------------- 155
1A6O            -------------------------------------------------- 150
1LPUA           -------------------------------------------------- 150
CK2A1           -------------------------------------------------- 150
CK2A1-RS        -------------------------------------------------- 150
CK2A2           -------------------------------------------------- 150
HSER            -------------------------------------------------- 156
SLOB            -------------------------------------------------- 171
CDC7            ESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLT 293
1CSN            -------------------------------------------------- 163
CK1G1           -------------------------------------------------- 164
CK1G3           -------------------------------------------------- 163
CK1G2           -------------------------------------------------- 163
CK1A            -------------------------------------------------- 161
CK1A2           -------------------------------------------------- 161
1CKJA           -------------------------------------------------- 161
CK1D            -------------------------------------------------- 161
CK1E            -------------------------------------------------- 161
TTBK1           -------------------------------------------------- 162
TTBK2           -------------------------------------------------- 162
TLK1            -------------------------------------------------- 171
TLK2            -------------------------------------------------- 172
GPRK4           -------------------------------------------------- 157
GPRK6           -------------------------------------------------- 157
GPRK5           -------------------------------------------------- 157
RHOK            -------------------------------------------------- 160
GPRK7           -------------------------------------------------- 157
BARK1           -------------------------------------------------- 157
BARK2           -------------------------------------------------- 157
TTK             -------------------------------------------------- 156
RIPK1           -------------------------------------------------- 162
HASPIN          -------------------------------------------------- 228
GCN2            -------------------------------------------------- 303
HRI             -------------------------------------------------- 317
KIS             -------------------------------------------------- 172
PDK1            -------------------------------------------------- 155
PKR             -------------------------------------------------- 175
PEK             -------------------------------------------------- 383
PRPK            -------------------------------------------------- 164
DOMAIN2_OBSCN   ------------------------------GN-AQSLSQEKVL------- 151
DOMAIN2_SPEG    ------------------------------GS-AQPYNPQALR------- 151
LMR1            ------------------------------GL-AHCKYREDYFV------ 161
LMR2            ------------------------------GI-GFSRYKEDYIE------ 161
LMR3            ------------------------------GL-AHSNYKEDYYL------ 166
SGK307          ---------------------------------MLESEDRGV-------- 67
STLK5           ------------------------------RS-NLSMISHGQ-------- 157
STLK6           ------------------------------SH-LHSLVKHGQ-------- 157
STLK6-RS        ------------------------------SH-LHSLVKHGQ-------- 157
OBSCN           ------------------------------GF-AQNITPAE--------- 151
SPEG            ------------------------------GN-AQELTPGE--------- 152
TRAD            ------------------------------ED-AVQISGHF--------- 152
TRIO            ------------------------------GD-AVQLNTTY--------- 152
SGK223          ------------------------------GTLSPAAGPASPEGPREKQL 190
SGK269          ------------------------------GT-AQGFGPAEPS-PTSSYP 163
ALK1            -------------------------------------------------- 163
ALK2            -------------------------------------------------- 163
IRAK4           -------------------------------------------------- 158
BMPR2           -------------------------------------------------- 169
TGFBR2          -------------------------------------------------- 170
ACTR2           -------------------------------------------------- 164
ACTR2B          -------------------------------------------------- 165
1B6CB           -------------------------------------------------- 163
TGFBR1          -------------------------------------------------- 163
ALK4            -------------------------------------------------- 163
ALK7            -------------------------------------------------- 163
BMPR1A          -------------------------------------------------- 163
BMPR1B          -------------------------------------------------- 163
IRAK1           -------------------------------------------------- 168
IRAK2           -------------------------------------------------C 150
IRAK3           -------------------------------------------------F 153
MISR2           -------------------------------------------------V 155
MYT1            -------------------------------------------------E 148
SBK             -------------------------------------------------R 148
SGK110          -------------------------------------------------P 147
SGK069          -------------------------------------------------P 148
SGK496          -------------------------------------------------P 150
NIK             -------------------------------------------------C 141
SGK424          -------------------------------------------------- 0
SURTK106        -------------------------------------------------E 162
IKKE            -------------------------------------------------- 159
TBK1            -------------------------------------------------- 159
MOS             -------------------------------------------------- 174
LKB1            -------------------------------------------------- 159
CAMKK1          -------------------------------------------------- 185
CAMKK2          -------------------------------------------------- 177
PASK            -------------------------------------------------- 158
PIM1            -------------------------------------------------- 158
PIM3            -------------------------------------------------- 159
PIM2            -------------------------------------------------- 160
COT             -------------------------------------------------- 149
SCYL2           -------------------------------------------------- 188
FUSED           -------------------------------------------------- 154
ULK1            -------------------------------------------------- 160
ULK2            -------------------------------------------------- 160
ULK3            -------------------------------------------------- 154
ULK4            ---------------------------------------------FFALV 139
IRE1            -------------------------------------------------- 153
IRE2            -------------------------------------------------- 153
RNASEL          -------------------------------------------------W 142
MPSK1           ---------------------------------------------TLQDW 170
PINK1           ---------------------------------------------PFSSW 248
ALK             -------------------------------------------------- 166
LTK             -------------------------------------------------- 166
ROS             -------------------------------------------------- 169
IGF1R           -------------------------------------------------- 166
1IR3A           -------------------------------------------------- 166
INSR            -------------------------------------------------- 166
IRR             -------------------------------------------------- 166
1M14A           -------------------------------------------------- 156
EGFR            -------------------------------------------------- 156
HER2/ERBB2      -------------------------------------------------- 156
HER4/ERBB4      -------------------------------------------------- 155
HER3/ERBB3      -------------------------------------------------- 155
ITK             -------------------------------------------------- 149
TEC             -------------------------------------------------- 148
TXK             -------------------------------------------------- 149
BMX             -------------------------------------------------- 149
1K2PA           -------------------------------------------------- 149
BTK             -------------------------------------------------- 149
CCK4            -------------------------------------------------- 164
ROR1            -------------------------------------------------- 172
ROR2            -------------------------------------------------- 172
MUSK            -------------------------------------------------- 180
TRKA            -------------------------------------------------- 170
TRKB            -------------------------------------------------- 168
TRKC            -------------------------------------------------- 171
DDR1            -------------------------------------------------- 186
DDR2            -------------------------------------------------- 177
RYK             -------------------------------------------------- 165
JAK1            -------------------------------------------------- 158
JAK2            -------------------------------------------------- 158
JAK3            -------------------------------------------------- 158
ACK             -------------------------------------------------- 157
TYK2            -------------------------------------------------- 157
TNK1            -------------------------------------------------- 160
EPHA1           -------------------------------------------------- 160
EPHA10          -------------------------------------------------- 159
FAK             -------------------------------------------------- 158
EPHB6           -------------------------------------------------- 149
EPHA2           -------------------------------------------------- 162
EPHA8           -------------------------------------------------- 161
EPHA6           -------------------------------------------------- 203
EPHB1           -------------------------------------------------- 162
EPHB2           -------------------------------------------------- 162
EPHB3           -------------------------------------------------- 162
EPHB4           -------------------------------------------------- 162
EPHA7           -------------------------------------------------- 161
EPHA4           -------------------------------------------------- 161
EPHA3           -------------------------------------------------- 161
EPHA5           -------------------------------------------------- 161
PYK2            -------------------------------------------------- 158
CSK             -------------------------------------------------- 149
CTK             -------------------------------------------------- 147
1IEPA           -------------------------------------------------- 155
ABL             -------------------------------------------------- 155
ARG             -------------------------------------------------- 155
BRK             -------------------------------------------------- 155
SRM             -------------------------------------------------- 154
FRK             -------------------------------------------------- 157
FGR             -------------------------------------------------- 153
FYN             -------------------------------------------------- 153
SRC             -------------------------------------------------- 153
YES             -------------------------------------------------- 153
HCK             -------------------------------------------------- 153
LYN             -------------------------------------------------- 154
3LCK            -------------------------------------------------- 153
LCK             -------------------------------------------------- 153
BLK             -------------------------------------------------- 152
FER             -------------------------------------------------- 155
FES             -------------------------------------------------- 156
SYK             -------------------------------------------------- 159
ZAP70           -------------------------------------------------- 159
FGFR1           -------------------------------------------------- 180
FGFR2           -------------------------------------------------- 180
FGFR3           -------------------------------------------------- 180
FGFR4           -------------------------------------------------- 180
RET             -------------------------------------------------- 185
TIE1            -------------------------------------------------- 172
1FVRA           -------------------------------------------------- 172
TIE2            -------------------------------------------------- 172
FLT1            -------------------------------------------------- 230
KDR             -------------------------------------------------- 229
KDR_AVE         -------------------------------------------------- 169
FLT4            -------------------------------------------------- 227
FMS             -------------------------------------------------- 231
FLT3            -------------------------------------------------- 236
KIT             -------------------------------------------------- 238
PDGFRA          -------------------------------------------------- 260
PDGFRB          -------------------------------------------------- 261
MER             -------------------------------------------------- 171
AXL             -------------------------------------------------- 171
TYRO3           -------------------------------------------------- 172
MET             -------------------------------------------------- 163
RON             -------------------------------------------------- 163
HH498           -------------------------------------------------- 158
LZK             -------------------------------------------------- 142
DLK             -------------------------------------------------- 142
MLK1            -------------------------------------------------- 162
MLK3            -------------------------------------------------- 162
MLK2            -------------------------------------------------- 162
MLK4            -------------------------------------------------- 177
ZAK             -------------------------------------------------- 147
TAK1            -------------------------------------------------- 151
KSR1            -------------------------------------------------- 155
KSR2            -------------------------------------------------- 155
ARAF            -------------------------------------------------- 152
RAF1            -------------------------------------------------- 152
BRAF            -------------------------------------------------- 152
LRRK2           -------------------------------------------------- 151
ANKRD3          -------------------------------------------------- 155
SGK288          -------------------------------------------------- 156
RIPK2           -------------------------------------------------- 164
RIPK3           -------------------------------------------------- 155
MLKL            -------------------------------------------------- 159
ANPA            -------------------------------------------------- 158
ANPB            -------------------------------------------------- 158
CYGD            -------------------------------------------------- 166
CYGF            -------------------------------------------------- 171
TBCK            -------------------------------------------------- 132
ERK1            -------------------------------------------------- 158
3ERK            -------------------------------------------------- 158
ERK2            -------------------------------------------------- 158
ERK5            -------------------------------------------------- 162
1JNK            -------------------------------------------------- 150
1PMNA           -------------------------------------------------- 155
JNK3            -------------------------------------------------- 155
JNK1            -------------------------------------------------- 155
JNK2            -------------------------------------------------- 155
1P38            -------------------------------------------------- 155
P38A            -------------------------------------------------- 155
P38B            -------------------------------------------------- 163
P38D            -------------------------------------------------- 154
P38G            -------------------------------------------------- 155
NLK             -------------------------------------------------- 158
ERK7            -------------------------------------------------- 179
ERK3            -------------------------------------------------- 167
ERK4            -------------------------------------------------- 164
ICK             -------------------------------------------------- 152
MAK             -------------------------------------------------- 152
PCTAIRE1        -------------------------------------------------- 153
PCTAIRE2        -------------------------------------------------- 153
PCTAIRE3        -------------------------------------------------- 153
PFTAIRE1        -------------------------------------------------- 153
PFTAIRE2        -------------------------------------------------- 153
CDC2            -------------------------------------------------- 156
1HCL            -------------------------------------------------- 151
CDK2            -------------------------------------------------- 155
CDK3            -------------------------------------------------- 155
CDK5            -------------------------------------------------- 154
CDK7            -------------------------------------------------- 157
CDK4            -------------------------------------------------- 164
1BLXA           -------------------------------------------------- 162
CDK6            -------------------------------------------------- 162
PITSLRE         -------------------------------------------------- 156
CDK10           -------------------------------------------------- 156
CDK9            -------------------------------------------------- 165
CHED            -------------------------------------------------- 165
CRK7            -------------------------------------------------- 165
CCRK            -------------------------------------------------- 156
CDK11           -------------------------------------------------- 169
CDK8            -------------------------------------------------- 169
IKKA            -------------------------------------------------- 161
IKKB            -------------------------------------------------- 162
1PHK            -------------------------------------------------- 159
PHKG1           -------------------------------------------------- 159
PHKG2           -------------------------------------------------- 158
CAMK2A          -------------------------------------------------- 155
CAMK2B          -------------------------------------------------- 155
CAMK2G          -------------------------------------------------- 155
CAMK2D          -------------------------------------------------- 155
CASK            -------------------------------------------------- 162
1IA8A           -------------------------------------------------- 150
CHK1            -------------------------------------------------- 153
CLK1            -------------------------------------------------- 173
CLK4            -------------------------------------------------- 172
CLK2            -------------------------------------------------- 173
CLK3            -------------------------------------------------- 173
MAP2K5          -------------------------------------------------- 151
MAP2K3          -------------------------------------------------- 161
MAP2K6          -------------------------------------------------- 161
MAP2K4          -------------------------------------------------- 162
MAP2K7          -------------------------------------------------- 158
MAP2K1          -------------------------------------------------- 156
MAP2K2          -------------------------------------------------- 156
CDKL5           -------------------------------------------------- 155
CDKL1           -------------------------------------------------- 154
CDKL4           -------------------------------------------------- 153
CDKL2           -------------------------------------------------- 154
CDKL3           -------------------------------------------------- 153
1I09B           -------------------------------------------------- 157
GSK3B           -------------------------------------------------- 157
1J1BA           -------------------------------------------------- 157
GSK3A           -------------------------------------------------- 157
LATS1           --------------------------------------------PSSCRC 183
LATS2           --------------------------------------------VSNCRC 183
NDR1            --------------------------------------------NMNSK- 177
NDR2            --------------------------------------------NMNSK- 177
MAST1           -------------------------------------------------- 169
MAST4           -------------------------------------------------- 169
MAST2           -------------------------------------------------- 169
MAST3           -------------------------------------------------- 169
MRCKA           -------------------------------------------------- 157
MRCKB           -------------------------------------------------- 157
DMPK2           -------------------------------------------------- 157
DMPK1           -------------------------------------------------- 157
ROCK1           -------------------------------------------------- 155
ROCK2           -------------------------------------------------- 155
CRIK            -------------------------------------------------- 157
MASTL           -------------------------------------------------- 153
1O6LA           -------------------------------------------------- 154
AKT2            -------------------------------------------------- 154
AKT1            -------------------------------------------------- 155
AKT3            -------------------------------------------------- 154
MSK1            -------------------------------------------------- 160
MSK2            -------------------------------------------------- 160
P70S6K          -------------------------------------------------- 158
P70S6KB         -------------------------------------------------- 158
RSK1            -------------------------------------------------- 156
RSK3            -------------------------------------------------- 156
RSK2            -------------------------------------------------- 156
RSK4            -------------------------------------------------- 156
1FOTA           -------------------------------------------------- 151
1CDKA           -------------------------------------------------- 151
PKACA           -------------------------------------------------- 151
PKACB           -------------------------------------------------- 151
PKACG           -------------------------------------------------- 151
PRKX            -------------------------------------------------- 151
PRKY            -------------------------------------------------- 151
PKCA            -------------------------------------------------- 155
PKCB            -------------------------------------------------- 155
PKCG            -------------------------------------------------- 160
PKCE            -------------------------------------------------- 155
PKCH            -------------------------------------------------- 155
PKCD            -------------------------------------------------- 155
PKCT            -------------------------------------------------- 155
PKCI            -------------------------------------------------- 155
PKCZ            -------------------------------------------------- 155
PKN1            -------------------------------------------------- 156
PKN2            -------------------------------------------------- 156
PKN3            -------------------------------------------------- 156
SGK             -------------------------------------------------- 155
SGK2            -------------------------------------------------- 155
SGK3            -------------------------------------------------- 155
PKG1            -------------------------------------------------- 154
PKG2            -------------------------------------------------- 153
AURB            -------------------------------------------------- 152
AURC            -------------------------------------------------- 152
AURA            -------------------------------------------------- 152
AURORA2_AVE     -------------------------------------------------- 148
PLK1            -------------------------------------------------- 154
PLK2            -------------------------------------------------- 154
PLK3            -------------------------------------------------- 154
PLK4            -------------------------------------------------- 155
NEK11           -------------------------------------------------- 159
YANK1           -------------------------------------------------- 154
YANK2           -------------------------------------------------- 154
YANK3           -------------------------------------------------- 154
SGK494          -------------------------------------------------- 153
DOMAIN2_MSK1    -------------------------------------------------- 153
DOMAIN2_MSK2    -------------------------------------------------- 149
DOMAIN2_RSK1    -------------------------------------------------- 153
DOMAIN2_RSK2    -------------------------------------------------- 153
DOMAIN2_RSK3    -------------------------------------------------- 153
DOMAIN2_RSK4    -------------------------------------------------- 153
DRAK1           -------------------------------------------------- 159
DRAK2           -------------------------------------------------- 159
1JKSA           -------------------------------------------------- 161
DAPK1           -------------------------------------------------- 161
DAPK3           -------------------------------------------------- 161
DAPK2           -------------------------------------------------- 161
SGK085          -------------------------------------------------- 154
CAMLCK          -------------------------------------------------- 154
SKMLCK          -------------------------------------------------- 154
SMMLCK          -------------------------------------------------- 154
1KOBA           -------------------------------------------------- 154
1TKIA           -------------------------------------------------- 153
TTN             -------------------------------------------------- 153
PKD1            -------------------------------------------------- 157
PKD3            -------------------------------------------------- 157
PKD2            -------------------------------------------------- 157
PSKH1           -------------------------------------------------- 156
PSKH2           -------------------------------------------------- 156
CAMK1A          -------------------------------------------------- 155
CAMK1D          -------------------------------------------------- 155
CAMK1B          -------------------------------------------------- 154
CAMK1G          -------------------------------------------------- 153
CAMK4           -------------------------------------------------- 152
DCAMKL1         -------------------------------------------------- 154
DCAMKL2         -------------------------------------------------- 154
DCAMKL3         -------------------------------------------------- 154
CHK2            -------------------------------------------------- 161
MAPKAPK2        -------------------------------------------------- 156
MAPKAPK3        -------------------------------------------------- 155
MAPKAPK5        -------------------------------------------------- 158
MNK1            -------------------------------------------------- 164
MNK2            -------------------------------------------------- 163
VACAMKL         -------------------------------------------------- 153
GCK             -------------------------------------------------- 151
KHS1            -------------------------------------------------- 151
KHS2            -------------------------------------------------- 151
HPK1            -------------------------------------------------- 151
MST1            -------------------------------------------------- 150
MST2            -------------------------------------------------- 150
MST3            -------------------------------------------------- 151
YSK1            -------------------------------------------------- 151
MST4            -------------------------------------------------- 151
LOK             -------------------------------------------------- 152
SLK             -------------------------------------------------- 152
MAP3K4          -------------------------------------------------- 155
MAP3K2          -------------------------------------------------- 161
MAP3K3          -------------------------------------------------- 161
MAP3K8          -------------------------------------------------- 162
MAP3K5          -------------------------------------------------- 160
MAP3K7          -------------------------------------------------- 151
MAP3K6          -------------------------------------------------- 150
PAK1            -------------------------------------------------- 150
PAK3            -------------------------------------------------- 150
PAK2            -------------------------------------------------- 151
PAK4            -------------------------------------------------- 150
PAK5            -------------------------------------------------- 150
PAK6            -------------------------------------------------- 150
OSR1            -------------------------------------------------- 165
STLK3           -------------------------------------------------- 165
TAO1            -------------------------------------------------- 152
TAO3            -------------------------------------------------- 152
TAO2            -------------------------------------------------- 151
MYO3A           -------------------------------------------------- 160
MYO3B           -------------------------------------------------- 160
ZC1/HGK         -------------------------------------------------- 159
ZC3/MINK        -------------------------------------------------- 159
ZC2/TNIK        -------------------------------------------------- 159
ZC4/NRK         -------------------------------------------------- 183
MAP3K1          -------------------------------------------------- 162
GAK             -------------------------------------------------- 168
SGK495          -------------------------------------------------- 71
TRB1            -------------------------------------------------- 139
TRB2            -------------------------------------------------- 144
TRB3            -------------------------------------------------- 142
SSTK            -------------------------------------------------- 153
TSSK3           -------------------------------------------------- 152
TSSK1           -------------------------------------------------- 154
TSSK2           -------------------------------------------------- 154
TSSK4           -------------------------------------------------- 164
HUNK            -------------------------------------------------- 158
SNRK            -------------------------------------------------- 154
NIM1            -------------------------------------------------- 152
MELK            -------------------------------------------------- 151
BRSK1           -------------------------------------------------- 152
BRSK2           -------------------------------------------------- 152
MARK1           -------------------------------------------------- 152
MARK2           -------------------------------------------------- 152
MARK3           -------------------------------------------------- 152
MARK4           -------------------------------------------------- 152
QIK             -------------------------------------------------- 152
SIK             -------------------------------------------------- 152
QSK             -------------------------------------------------- 152
AMPKA1          -------------------------------------------------- 153
AMPKA2          -------------------------------------------------- 153
NUAK1           -------------------------------------------------- 153
NUAK2           -------------------------------------------------- 152
BIKE            -------------------------------------------------- 164
AAK1            -------------------------------------------------- 165
LIMK1           -----------------------------------------------TQP 154
LIMK2           -----------------------------------------------KRA 153
TESK1           -----------------------------------------------EGA 154
TESK2           -----------------------------------------------MGS 134
WNK1            -----------------------------------------------SFA 160
WNK3            -----------------------------------------------SFA 160
WNK2            -----------------------------------------------SFA 160
WNK4            -----------------------------------------------SFA 160
NEK10           -----------------------------------------------SKL 168
NEK6            -----------------------------------------------TAA 160
NEK7            -----------------------------------------------TAA 160
NEK2            -----------------------------------------------SFA 166
NEK1            -----------------------------------------------ELA 157
NEK5            -----------------------------------------------ELA 158
NEK3            -----------------------------------------------AFA 156
NEK4            -----------------------------------------------DMA 158
NEK8            -------------------------------------------------- 154
NEK9            -----------------------------------------------SMA 157
NRBP1           -----------------------------------------------KTC 169
NRBP2           -----------------------------------------------RAE 183
CLIK1           -------------------------------------------------- 205
CLIK1L          -------------------------------------------------- 202
STK33           -------------------------------------------------- 159
DOMAIN2_GCN2    -------------------------------------------------- 180
SCYL1           -------------------------------------------------- 151
SCYL3           -------------------------------------------------- 140
DOMAIN2_JAK1    -------------------------------------------------- 171
DOMAIN2_TYK2    -------------------------------------------------- 185
DOMAIN2_JAK2    -------------------------------------------------- 169
DOMAIN2_JAK3    -------------------------------------------------- 165
ILK             -------------------------------------------------- 159
LRRK1           -------------------------------------------------- 184
PBK             -------------------------------------------------- 176
WEE1            -------------------------------------------------- 179
WEE1B           -------------------------------------------------- 183
SGK071          -------------------------------------------------- 170
PIK3R4          -------------------------------------------------- 168
MSSK1           -------------------------------------------------- 297
SRPK1           -------------------------------------------------- 418
SRPK2           -------------------------------------------------- 450
RSKL1           -------------------------------------------------- 142
RSKL2           -------------------------------------------------- 294
SGK396          -------------------------------------------------- 157
VRK1            -------------------------------------------------- 166
VRK2            -------------------------------------------------- 163
VRK3            -------------------------------------------------- 111
BUB1            -------------------------------------------------- 180
BUBR1           -------------------------------------------------- 173
SGK196          -------------------------------------------------- 169
SGK493          -------------------------------------------------- 174
                                                                  

DYRK1A          --------------------YQYIQSRFYRSPEV---------------- 174
DYRK1B          --------------------YQYIQSRFYRSPEV---------------- 174
DYRK2           --------------------YTYIQSRFYRAPEV---------------- 172
DYRK3           --------------------YTYIQSRFYRAPEI---------------- 172
DYRK4           --------------------YTYIQSRFYRSPEV---------------- 172
HIPK1           --------------------STYLQSRYYRAPEI---------------- 174
HIPK2           --------------------STYLQSRYYRAPEI---------------- 174
HIPK3           --------------------STYLQSRYYRAPEI---------------- 174
HIPK4           ---------------------PYIQSRFYRAPEI---------------- 176
PRP4            --------------------TPYLVSRFYRAPEI---------------- 174
MOK             --------------------TEYISTRWYRAPEC---------------- 169
1A6O            --------------------NVRVASRYFKGPEL---------------- 164
1LPUA           --------------------NVRVASRYFKGPEL---------------- 164
CK2A1           --------------------NVRVASRYFKGPEL---------------- 164
CK2A1-RS        --------------------NVRVASRYFKGPEL---------------- 164
CK2A2           --------------------NVRVASRYFKGPEL---------------- 164
HSER            ---------------------------LWTAPEH---------------- 163
SLOB            -------------------------------------------------- 171
CDC7            CDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEV---------------- 327
1CSN            ------------------KK-NLSGTARYMSINT---------------- 178
CK1G1           ------------------HK-SLTGTARYMSINT---------------- 179
CK1G3           ------------------HK-SLTGTARYMSINT---------------- 178
CK1G2           ------------------HK-SLTGTARYMSINT---------------- 178
CK1A            ------------------DK-NLTGTARYASINA---------------- 176
CK1A2           ------------------DK-HLIGTVRYASINA---------------- 176
1CKJA           ------------------NK-NLTGTARYASINT---------------- 176
CK1D            ------------------NK-NLTGTARYASINT---------------- 176
CK1E            ------------------NK-NLTGTARYASINT---------------- 176
TTBK1           ------------------VA-GFRGTVRYASVNA---------------- 177
TTBK2           ------------------VA-GFRGTVRYASINA---------------- 177
TLK1            -------------------TSQGAGTYWYLPPEC---------------- 186
TLK2            -------------------TSQGAGTYWYLPPEC---------------- 187
GPRK4           --------------------RGRVGTVGYMAPEV---------------- 171
GPRK6           --------------------KGRVGTVGYMAPEV---------------- 171
GPRK5           --------------------RGRVGTVGYMAPEV---------------- 171
RHOK            --------------------KGYAGTPGFMAPEL---------------- 174
GPRK7           --------------------TQRAGTNGYMAPEI---------------- 171
BARK1           --------------------HASVGTHGYMAPEV---------------- 171
BARK2           --------------------HASVGTHGYMAPEV---------------- 171
TTK             --------------------DSQVGTVNYMPPEA---------------- 170
RIPK1           ---------------VDGTAKKNGGTLYYMAPEH---------------- 181
HASPIN          -----------------------TGDGDYQFDIY---------------- 239
GCN2            --------------DPSGHLTGMVGTALYVSPEV---------------- 323
HRI             --------------T--PTHTSRVGTCLYASPEQ---------------- 335
KIS             --------------DGYRAPEAELQNCLAQAGLQ---------------- 192
PDK1            -----------------ARANSFVGTAQYVSPEL---------------- 172
PKR             --------------D--GKRTRSKGTLRYMSPEQ---------------- 193
PEK             --------------PAYARHTGQVGTKLYMSPEQ---------------- 403
PRPK            -------------------------------------------------- 164
DOMAIN2_OBSCN   ------------------PSDKFKDYLETMAPEL---------------- 167
DOMAIN2_SPEG    ------------------PLGHRTGTLEFMAPEM---------------- 167
LMR1            ------------------TADQLWVPLRWIAPEL---------------- 177
LMR2            ------------------TDDKKVFPLRWTAPEL---------------- 177
LMR3            ------------------TPERLWIPLRWAAPEL---------------- 182
SGK307          ----------QRDLT-RVP-LPTQL-YNWAAPEV---------------- 88
STLK5           ----------RQRVVHDFPKYSVKV-LPWLSPEV---------------- 180
STLK6           ----------RHRAVYDFPQFSTSV-QPWLSPEL---------------- 180
STLK6-RS        ----------RHRAVYDFPQFSTSV-QPWLSPEL---------------- 180
OBSCN           ------------------LQFSQYGSPEFVSPEI---------------- 167
SPEG            ------------------PQYCQYGTPEFVAPEI---------------- 168
TRAD            ------------------HIHHLLGNPEFAAPEV---------------- 168
TRIO            ------------------YIHQLLGNPEFAAPEI---------------- 168
SGK223          PRLIISNFLKAKQKPGGTPNLQQKKSQARLAPEI---------------- 224
SGK269          TRLIVSNFSQAKQK-SHLVDPEILRDQSRLAPEI---------------- 196
ALK1            ------------------GNNPRVGTKRYMAPEV---------------- 179
ALK2            ------------------GNNPRVGTKRYMAPEV---------------- 179
IRAK4           ------------------MTSRIVGTTAYMAPEA---------------- 174
BMPR2           ------------------AAISEVGTIRYMAPEV---------------- 185
TGFBR2          ------------------ANSGQVGTARYMAPEV---------------- 186
ACTR2           -------------------THGQVGTRRYMAPEV---------------- 179
ACTR2B          -------------------THGQVGTRRYMAPEV---------------- 180
1B6CB           ------------------APNHRVGTKRYMAPEV---------------- 179
TGFBR1          ------------------APNHRVGTKRYMAPEV---------------- 179
ALK4            ------------------APNQRVGTKRYMAPEV---------------- 179
ALK7            ------------------PQNPKVGTKRYMAPEM---------------- 179
BMPR1A          ------------------PLNTRVGTKRYMAPEV---------------- 179
BMPR1B          ------------------PPNTRVGTKRYMPPEV---------------- 179
IRAK1           ------------------RTQTVRGTLAYLPEEY---------------- 184
IRAK2           PV----NKRSKYTMMKTHLL---RTSAAYLPEDF---------------- 177
IRAK3           RSHL------EHQSCTINMTSSSSKHLWYMPEEY---------------- 181
MISR2           LPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPEL---------------- 189
MYT1            LGT----AGAGE---------VQEGDPRYMAPEL---------------- 169
SBK             VGCRVK---------------RVSGTIPYTAPEV---------------- 167
SGK110          EGSPTP---------------APPVPLPTAPPEL---------------- 166
SGK069          RGTLLR---------------LAGPPIPYTAPEL---------------- 167
SGK496          EAMMSG---------------SIVGTPIHMAPEL---------------- 169
NIK             LQ----PDGLGKSLLTGDYI---PGTETHMAPEV---------------- 168
SGK424          -------------------------------------------------- 0
SURTK106        VY----TRGAISSTQTIPL--------KWLAPER---------------- 184
IKKE            -----------------EKFVSVYGTEEYLHPDM---------------- 176
TBK1            -----------------EQFVSLYGTEEYLHPDM---------------- 176
MOS             -----------------TPSYPLGGTYTHRAPEL---------------- 191
LKB1            -----------------DTCRTSQGSPAFQPPEI---------------- 176
CAMKK1          -----------------AQLSSTAGTPAFMAPEA---------------- 202
CAMKK2          -----------------ALLSNYVGTPAFMAPES---------------- 194
PASK            -----------------KLFYTFCGTIEYCAPEV---------------- 175
PIM1            -----------------TVYTDFDGTRVYSPPEW---------------- 175
PIM3            -----------------TVYTDFDGTRVYSPPEW---------------- 176
PIM2            -----------------EPYTDFDGTRVYSPPEW---------------- 177
COT             --------------------KDLRGTEIYMSPEV---------------- 163
SCYL2           ----------------PNLPSLCLPNPEYLAPEY---------------- 206
FUSED           --------------------TSIKGTPLYMSPEL---------------- 168
ULK1            ----------------MMAAT-LCGSPMYMAPEV---------------- 177
ULK2            ----------------MMAAT-LCGSPMYMAPEV---------------- 177
ULK3            ----------------DEKHV-LRGSPLYMAPEM---------------- 171
ULK4            AAEEGGGDNGENVLKKSMKS-RVKGSPVYTAPEV---------------- 172
IRE1            --------------SFSRRS-GVPGTEGWIAPEM---------------- 172
IRE2            --------------SFSLHS-GIPGTEGWMAPEL---------------- 172
RNASEL          AGD----------------------------------------------- 145
MPSK1           AAQ--------------------RCTISYRAPEL---------------- 184
PINK1           YVD-------------------RGGNGCLMAPEV---------------- 263
ALK             -----------YYRKG----GCAMLPVKWMPPEA---------------- 185
LTK             -----------YYRRG----DRALLPVKWMPPEA---------------- 185
ROS             -----------YYRKR----GEGLLPVRWMAPES---------------- 188
IGF1R           -----------YYRKG----GKGLLPVRWMSPES---------------- 185
1IR3A           -----------YYRKG----GKGLLPVRWMAPES---------------- 185
INSR            -----------YYRKG----GKGLLPVRWMAPES---------------- 185
IRR             -----------YYRKG----GKGLLPVRWMAPES---------------- 185
1M14A           -----------EYHAE-----GGKVPIKWMALES---------------- 174
EGFR            -----------EYHAE-----GGKVPIKWMALES---------------- 174
HER2/ERBB2      -----------EYHAD-----GGKVPIKWMALES---------------- 174
HER4/ERBB4      -----------KEYNA----DGGKMPIKWMALEC---------------- 174
HER3/ERBB3      -----------KQLLY----SEAKTPIKWMALES---------------- 174
ITK             -----------YTSST----G-TKFPVKWASPEV---------------- 167
TEC             -----------QYTSS----SGAKFPVKWCPPEV---------------- 167
TXK             -----------YVSSF----G-AKFPIKWSPPEV---------------- 167
BMX             -----------YVSSV----G-TKFPVKWSAPEV---------------- 167
1K2PA           -----------YTSSV----G-SKFPVRWSPPEV---------------- 167
BTK             -----------YTSSV----G-SKFPVRWSPPEV---------------- 167
CCK4            -----------YYHFR-----QAWVPLRWMSPEA---------------- 182
ROR1            -----------YYRVQ----SKSLLPIRWMPPEA---------------- 191
ROR2            -----------YYKLL----GNSLLPIRWMAPEA---------------- 191
MUSK            -----------YYKAN----ENDAIPIRWMPPES---------------- 199
TRKA            -----------YYRVG----GRTMLPIRWMPPES---------------- 189
TRKB            -----------YYRVG----GHTMLPIRWMPPES---------------- 187
TRKC            -----------YYRVG----GHTMLPIRWMPPES---------------- 190
DDR1            -----------YYRVQ----GRAVLPIRWMAWEC---------------- 205
DDR2            -----------YYRIQ----GRAVLPIRWMSWES---------------- 196
RYK             -----------YHCLG----DNENRPVRWMALES---------------- 184
JAK1            -----------YYTVK----DDRDSPVFWYAPEC---------------- 177
JAK2            -----------YYKVK----EPGESPIFWYAPES---------------- 177
JAK3            -----------YYVVR----EPGQSPIFWYAPES---------------- 177
ACK             -----------HYVMQ----EHRKVPFAWCAPES---------------- 176
TYK2            -----------YYRVR----EDGDSPVFWYAPEC---------------- 176
TNK1            -----------RYVMG----GPRPIPYTWCAPES---------------- 179
EPHA1           -------------------Q-GGKIPIRWTAPEA---------------- 174
EPHA10          -------------------M-SGRSPALWAAPET---------------- 173
FAK             -------------------S-KGKLPIKWMAPES---------------- 172
EPHB6           -------------------Q-GPSCLLRWAAPEV---------------- 163
EPHA2           -------------------S-GGKIPIRWTAPEA---------------- 176
EPHA8           -------------------T-GGKIPIRWTAPEA---------------- 175
EPHA6           -------------------T-GGKIPIRWTAPEA---------------- 217
EPHB1           -------------------SLGGKIPVRWTAPEA---------------- 177
EPHB2           -------------------ALGGKIPIRWTAPEA---------------- 177
EPHB3           -------------------SLGGKIPIRWTAPEA---------------- 177
EPHB4           -------------------SLGGKIPIRWTAPEA---------------- 177
EPHA7           -------------------T-GGKIPVRWTAPEA---------------- 175
EPHA4           -------------------R-GGKIPIRWTAPEA---------------- 175
EPHA3           -------------------R-GGKIPIRWTSPEA---------------- 175
EPHA5           -------------------R-GGKIPIRWTAPEA---------------- 175
PYK2            -------------------S-VTRLPIKWMSPES---------------- 172
CSK             -------------------D-TGKLPVKWTAPEA---------------- 163
CTK             -------------------DS-SRLPVKWTAPEA---------------- 161
1IEPA           -------------------AG-AKFPIKWTAPES---------------- 169
ABL             -------------------AG-AKFPIKWTAPES---------------- 169
ARG             -------------------AG-AKFPIKWTAPES---------------- 169
BRK             ---------------------DHNIPYKWTAPEA---------------- 168
SRM             -------------------SS-SKIPVKWTAPEA---------------- 168
FRK             -------------------HE-IKLPVKWTAPEA---------------- 171
FGR             -------------------QG-SKFPIKWTAPEA---------------- 167
FYN             -------------------QG-AKFPIKWTAPEA---------------- 167
SRC             -------------------QG-AKFPIKWTAPEA---------------- 167
YES             -------------------QG-AKFPIKWTAPEA---------------- 167
HCK             -------------------EG-AKFPIKWTAPEA---------------- 167
LYN             -------------------EG-AKFPIKWTAPEA---------------- 168
3LCK            -------------------EG-AKFPIKWTAPEA---------------- 167
LCK             -------------------EG-AKFPIKWTAPEA---------------- 167
BLK             -------------------EG-AKFPIKWTAPEA---------------- 166
FER             -------------------GL-KQIPIKWTAPEA---------------- 169
FES             -------------------GGSRQVPVKWTAPEA---------------- 171
SYK             --------------------THGKWPVKWYAPEC---------------- 173
ZAP70           --------------------SAGKWPLKWYAPEC---------------- 173
FGFR1           --------------------TNGRLPVKWMAPEA---------------- 194
FGFR2           --------------------TNGRLPVKWMAPEA---------------- 194
FGFR3           --------------------TNGRLPVKWMAPEA---------------- 194
FGFR4           --------------------SNGRLPVKWMAPEA---------------- 194
RET             --------------------SQGRIPVKWMAIES---------------- 199
TIE1            --------------------TMGRLPVRWMAIES---------------- 186
1FVRA           --------------------TMGRLPVRWMAIES---------------- 186
TIE2            --------------------TMGRLPVRWMAIES---------------- 186
FLT1            --------------------GDTRLPLKWMAPES---------------- 244
KDR             --------------------GDARLPLKWMAPET---------------- 243
KDR_AVE         --------------------GDARLPLKWMAPET---------------- 183
FLT4            --------------------GSARLPLKWMAPES---------------- 241
FMS             --------------------GNARLPVKWMAPES---------------- 245
FLT3            --------------------GNARLPVKWMAPES---------------- 250
KIT             --------------------GNARLPVKWMAPES---------------- 252
PDGFRA          --------------------GSTFLPVKWMAPES---------------- 274
PDGFRB          --------------------GSTFLPLKWMAPES---------------- 275
MER             --------------------RIAKMPVKWIAIES---------------- 185
AXL             --------------------RIAKMPVKWIAIES---------------- 185
TYRO3           --------------------CASKLPVKWLALES---------------- 186
MET             --------------------TGAKLPVKWMALES---------------- 177
RON             --------------------RHARLPVKWMALES---------------- 177
HH498           ------------------M-TKQPGNLRWMAPEV---------------- 173
LZK             ------------------KM-SFAGTVAWMAPEV---------------- 157
DLK             ------------------KM-SFAGTVAWMAPEV---------------- 157
MLK1            ------------------KM-SAAGTYAWMAPEV---------------- 177
MLK3            ------------------QM-SAAGTYAWMAPEV---------------- 177
MLK2            ------------------KM-SAAGTYAWMAPEV---------------- 177
MLK4            ------------------KM-STAGTYAWMAPEV---------------- 192
ZAK             ------------------HM-SLVGTFPWMAPEV---------------- 162
TAK1            --------------------TNNKGSAAWMAPEV---------------- 165
KSR1            ------------------QLKLSHDWLCYLAPEI---------------- 171
KSR2            ------------------KLRIQNGWLCHLAPEI---------------- 171
ARAF            ------------------PLEQPSGSVLWMAAEV---------------- 168
RAF1            ------------------QVEQPTGSVLWMAPEV---------------- 168
BRAF            ------------------QFEQLSGSILWMAPEV---------------- 168
LRRK2           --------------------KTSEGTPGFRAPEV---------------- 165
ANKRD3          ------------------SMDGLFGTIAYLPPER---------------- 171
SGK288          ------------------R-SALRGMLSYIPPEM---------------- 171
RIPK2           ------------------KSAPEGGTIIYMPPEN---------------- 180
RIPK3           ------------------SG-EPGGTLGYLAPEL---------------- 170
MLKL            ------------------K-TDRVKSTAYLSPQE---------------- 174
ANPA            --------------------HTVYAKKLWTAPEL---------------- 172
ANPB            -------------------SHALYAKKLWTAPEL---------------- 173
CYGD            -------------------EPPRAEDQLWTAPEL---------------- 181
CYGF            -------------------EESSMEELLWTAPEL---------------- 186
TBCK            ----------------------PIGYPSYLAPEV---------------- 144
ERK1            ------------------FLTEYVATRWYRAPEI---------------- 174
3ERK            ------------------FLTEYVATRWYRAPEI---------------- 174
ERK2            ------------------FLTEYVATRWYRAPEI---------------- 174
ERK5            ------------------FMTEYVATRWYRAPEL---------------- 178
1JNK            ------------------MMTPYVVTRYYRAPEV---------------- 166
1PMNA           ------------------MMTPYVVTRYYRAPEV---------------- 171
JNK3            ------------------MMTPYVVTRYYRAPEV---------------- 171
JNK1            ------------------MMTPYVVTRYYRAPEV---------------- 171
JNK2            ------------------MMTPYVVTRYYRAPEV---------------- 171
1P38            -------------------MTGYVATRWYRAPEI---------------- 170
P38A            -------------------MTGYVATRWYRAPEI---------------- 170
P38B            -------------------MTGYVATRWYRAPEI---------------- 178
P38D            -------------------MTGYVVTRWYRAPEV---------------- 169
P38G            -------------------MTGYVVTRWYRAPEV---------------- 170
NLK             ------------------HMTQEVVTQYYRAPEI---------------- 174
ERK7            ------------------AVTEYVATRWYRAPEV---------------- 195
ERK3            ------------------HLSEGLVTKWYRSPRL---------------- 183
ERK4            ------------------YLSEGLVTKWYRSPRL---------------- 180
ICK             -------------------YTDYVSTRWYRAPEV---------------- 167
MAK             -------------------YTDYVSTRWYRAPEV---------------- 167
PCTAIRE1        -------------------YSNEVVTLWYRPPDI---------------- 168
PCTAIRE2        -------------------YSNEVVTLWYRPPDV---------------- 168
PCTAIRE3        -------------------YSNEVVTLWYRPPDV---------------- 168
PFTAIRE1        -------------------YSNEVVTLWYRPPDV---------------- 168
PFTAIRE2        -------------------YSSEVVTLWYRPPDA---------------- 168
CDC2            -------------------YTHEVVTLWYRSPEV---------------- 171
1HCL            -------------------YTHEVVTLWYRAPEI---------------- 166
CDK2            -------------------YTHEVVTLWYRAPEI---------------- 170
CDK3            -------------------YTHEVVTLWYRAPEI---------------- 170
CDK5            -------------------YSAEVVTLWYRPPDV---------------- 169
CDK7            -------------------YTHQVVTRWYRAPEL---------------- 172
CDK4            ------------------ALTPVVVTLWYRAPEV---------------- 180
1BLXA           ------------------ALTSVVVTLWYRAPEV---------------- 178
CDK6            ------------------ALTSVVVTLWYRAPEV---------------- 178
PITSLRE         -------------------YTPVVVTLWYRAPEL---------------- 171
CDK10           -------------------MTPKVVTLWYRAPEL---------------- 171
CDK9            ------------------RYTNRVVTLWYRPPEL---------------- 181
CHED            -------------------YTNKVITLWYRPPEL---------------- 180
CRK7            -------------------YTNKVITLWYRPPEL---------------- 180
CCRK            -------------------YTHQVATRWYRAPEL---------------- 171
CDK11           ------------------DLDPVVVTFWYRAPEL---------------- 185
CDK8            ------------------DLDPVVVTFWYRAPEL---------------- 185
IKKA            -----------------SLCTSFVGTLQYLAPEL---------------- 178
IKKB            -----------------SLCTSFVGTLQYLAPEL---------------- 179
1PHK            -----------------EKLREVCGTPSYLAPEI---------------- 176
PHKG1           -----------------ERLREVCGTPSYLAPEI---------------- 176
PHKG2           -----------------EKLRELCGTPGYLAPEI---------------- 175
CAMK2A          -----------------QAWFGFAGTPGYLSPEV---------------- 172
CAMK2B          -----------------QAWFGFAGTPGYLSPEV---------------- 172
CAMK2G          -----------------QAWFGFAGTPGYLSPEV---------------- 172
CAMK2D          -----------------QAWFGFAGTPGYLSPEV---------------- 172
CASK            -----------------LVAGGRVGTPHFMAPEV---------------- 179
1IA8A           -----------------RLLNKMCGTLPYVAPEL---------------- 167
CHK1            -----------------RLLNKMCGTLPYVAPEL---------------- 170
CLK1            -----------------EHHSTLVSTRHYRAPEV---------------- 190
CLK4            -----------------EHHSTLVSTRHYRAPEV---------------- 189
CLK2            -----------------EHHSTIVSTRHYRAPEV---------------- 190
CLK3            -----------------EHHTTIVATRHYRPPEV---------------- 190
MAP2K5          -----------------------VGTNAYMAPER---------------- 162
MAP2K3          -----------------------AGCKPYMAPER---------------- 172
MAP2K6          -----------------------AGCKPYMAPER---------------- 172
MAP2K4          -----------------------AGCRPYMAPER---------------- 173
MAP2K7          -----------------------AGCAAYMAPER---------------- 169
MAP2K1          -----------------------VGTRSYMSPER---------------- 167
MAP2K2          -----------------------VGTRSYMAPER---------------- 167
CDKL5           -------------------YTEYVATRWYRSPEL---------------- 170
CDKL1           -------------------YTDYVATRWYRSPEL---------------- 169
CDKL4           -------------------YTDYVATRWYRAPEL---------------- 168
CDKL2           -------------------YTDYVATRWYRAPEL---------------- 169
CDKL3           -------------------YTDYVATRWYRAPEL---------------- 168
1I09B           -------------------NVSYICSRYYRAPEL---------------- 172
GSK3B           -------------------NVSYICSRYYRAPEL---------------- 172
1J1BA           -------------------NVSYICSRYYRAPEL---------------- 172
GSK3A           -------------------NVSYICSRYYRAPEL---------------- 172
LATS1           GDRLKPLERRAARQHQRCLAHSLVGTPNYIAP------------------ 215
LATS2           GDRLKTLEQRARKQHQRCLAHSLVGTPNYIAP------------------ 215
NDR1            ------RKAETWKRNRRQLAFSTVGTPDYIAP------------------ 203
NDR2            ------RKAETWKKNRRQLAYSTVGTPDYIAP------------------ 203
MAST1           ------------------LDKQVCGTPEYIAP------------------ 183
MAST4           ------------------LDKQVCGTPEYIAP------------------ 183
MAST2           ------------------LDKQVCGTPEYIAP------------------ 183
MAST3           ------------------IDKQVCGTPEYIAP------------------ 183
MRCKA           -------------------SSVAVGTPDYISP------------------ 170
MRCKB           -------------------SSVAVGTPDYISP------------------ 170
DMPK2           -------------------SSVAVGTPDYISP------------------ 170
DMPK1           -------------------SLVAVGTPDYLSP------------------ 170
ROCK1           -------------------CDTAVGTPDYISP------------------ 168
ROCK2           -------------------CDTAVGTPDYISP------------------ 168
CRIK            -------------------AKLPIGTPDYMAP------------------ 170
MASTL           -------------------MMDILTTPSMAKPRQ---------------- 168
1O6LA           ------------------TMKTFCGTPEYLAPEV---------------- 170
AKT2            ------------------TMKTFCGTPEYLAPEV---------------- 170
AKT1            ------------------TMKTFCGTPEYLAPEV---------------- 171
AKT3            ------------------TMKTFCGTPEYLAPEV---------------- 170
MSK1            ------------------RAYSFCGTIEYMAPDI---------------- 176
MSK2            ------------------RTFSFCGTIEYMAPEI---------------- 176
P70S6K          ------------------VTHTFCGTIEYMAPEI---------------- 174
P70S6KB         ------------------VTHTFCGTIEYMAPEI---------------- 174
RSK1            ------------------RAYSFCGTIEYMAPEV---------------- 172
RSK3            ------------------KAYSFCGTVEYMAPEV---------------- 172
RSK2            ------------------KAYSFCGTVEYMAPEV---------------- 172
RSK4            ------------------KAYSFCGTVEYMAPEV---------------- 172
1FOTA           ------------------VTYTLCGTPDYIAPEV---------------- 167
1CDKA           ------------------RTWTLCGTPEYLAPEI---------------- 167
PKACA           ------------------RTWTLCGTPEYLAPEI---------------- 167
PKACB           ------------------RTWTLCGTPEYLAPEI---------------- 167
PKACG           ------------------RTWTLCGTPEYLAPEI---------------- 167
PRKX            ------------------RTWTLCGTPEYLAPEV---------------- 167
PRKY            ------------------RTWTLCGTPEYLAPEV---------------- 167
PKCA            ------------------TTRTFCGTPDYIAPEI---------------- 171
PKCB            ------------------TTKTFCGTPDYIAPEI---------------- 171
PKCG            ------------------TTRTFCGTPDYIAPEI---------------- 176
PKCE            ------------------TTTTFCGTPDYIAPEI---------------- 171
PKCH            ------------------TTATFCGTPDYIAPEI---------------- 171
PKCD            ------------------RASTFCGTPDYIAPEI---------------- 171
PKCT            ------------------KTNTFCGTPDYIAPEI---------------- 171
PKCI            ------------------TTSTFCGTPNYIAPEI---------------- 171
PKCZ            ------------------TTSTFCGTPNYIAPEI---------------- 171
PKN1            ------------------RTSTFCGTPEFLAPEV---------------- 172
PKN2            ------------------RTSTFCGTPEFLAPEV---------------- 172
PKN3            ------------------RTSTFCGTPEFLAPEV---------------- 172
SGK             ------------------TTSTFCGTPEYLAPEV---------------- 171
SGK2            ------------------TTSTFCGTPEYLAPEV---------------- 171
SGK3            ------------------TTTTFCGTPEYLAPEV---------------- 171
PKG1            ------------------KTWTFCGTPEYVAPEI---------------- 170
PKG2            ------------------KTWTFCGTPEYVAPEV---------------- 169
AURB            ------------------RRKTMCGTLDYLPPEM---------------- 168
AURC            ------------------ERKTMCGTLDYLPPEM---------------- 168
AURA            ------------------RRTTLCGTLDYLPPEM---------------- 168
AURORA2_AVE     -------------------------TLDYLPPEM---------------- 157
PLK1            ------------------RKKTLCGTPNYIAPEV---------------- 170
PLK2            ------------------RRRTICGTPNYLSPEV---------------- 170
PLK3            ------------------RKKTICGTPNYVAPEV---------------- 170
PLK4            ------------------KHYTLCGTPNYISPEI---------------- 171
NEK11           ------------------LATTLTGTPHYMSPEA---------------- 175
YANK1           -------------------ITTMAGTKPYMAPEM---------------- 169
YANK2           -------------------ASSMAGTKPYMAPEV---------------- 169
YANK3           -------------------ATALAGTKPYMAPEI---------------- 169
SGK494          -------------------AYTICGTLQYMAPEV---------------- 168
DOMAIN2_MSK1    -------------------LKTPCFTLHYAAPEL---------------- 168
DOMAIN2_MSK2    -------------------MQTPCFTLQYAAPEL---------------- 164
DOMAIN2_RSK1    -------------------LMTPCYTANFVAPEV---------------- 168
DOMAIN2_RSK2    -------------------LMTPCYTANFVAPEV---------------- 168
DOMAIN2_RSK3    -------------------LMTPCYTANFVAPEV---------------- 168
DOMAIN2_RSK4    -------------------LLTPCYTANFVAPEV---------------- 168
DRAK1           -------------------LREIMGTPEYVAPEI---------------- 174
DRAK2           -------------------LREIMGTPEYLAPEI---------------- 174
1JKSA           -------------------FKNIFGTPEFVAPEI---------------- 176
DAPK1           -------------------FKNIFGTPEFVAPEI---------------- 176
DAPK3           -------------------FKNIFGTPEFVAPEI---------------- 176
DAPK2           -------------------FKNIFGTPEFVAPEI---------------- 176
SGK085          -------------------LKVNFGTPEFLAPEV---------------- 169
CAMLCK          -------------------LKVNFGTPEFLAPEV---------------- 169
SKMLCK          -------------------LKVNFGTPEFLSPEV---------------- 169
SMMLCK          -------------------LKVLFGTPEFVAPEV---------------- 169
1KOBA           -------------------VKVTTATAEFAAPEI---------------- 169
1TKIA           -------------------FRLLFTAPEYYAPEV---------------- 168
TTN             -------------------FRLLFTAPEYYAPEV---------------- 168
PKD1            -------------------RRSVVGTPAYLAPEV---------------- 172
PKD3            -------------------RRSVVGTPAYLAPEV---------------- 172
PKD2            -------------------RRSVVGTPAYLAPEV---------------- 172
PSKH1           -------------------MKTTCGTPEYIAPEV---------------- 171
PSKH2           -------------------MKTLCGTPEYIAPEV---------------- 171
CAMK1A          -------------------LSTACGTPGYVAPEV---------------- 170
CAMK1D          -------------------MSTACGTPGYVAPEV---------------- 170
CAMK1B          -------------------LGTACGTPGYVAPEL---------------- 169
CAMK1G          -------------------MSTACGTPGYVAPEV---------------- 168
CAMK4           -------------------MKTVCGTPGYCAPEI---------------- 167
DCAMKL1         -------------------LYTVCGTPTYVAPEI---------------- 169
DCAMKL2         -------------------LYTVCGTPTYVAPEI---------------- 169
DCAMKL3         -------------------IFTVCGTPTYVAPEI---------------- 169
CHK2            -------------------MRTLCGTPTYLAPEV---------------- 176
MAPKAPK2        -------------------LTTPCYTPYYVAPEV---------------- 171
MAPKAPK3        -------------------LQTPCYTPYYVAPEV---------------- 170
MAPKAPK5        -------------------LMTPQFTPYYVAPQV---------------- 173
MNK1            -------------------LTTPCGSAEYMAPEV---------------- 179
MNK2            -------------------LLTPCGSAEYMAPEL---------------- 178
VACAMKL         -------------------IKEPCGTPEYL-------------------- 164
GCK             ------------------KRRSFIGTPYWMAPEV---------------- 167
KHS1            ------------------KRKSFIGTPYWMAPEV---------------- 167
KHS2            ------------------KRKSFIGTPYWMAPEV---------------- 167
HPK1            ------------------RRLSFIGTPYWMAPEV---------------- 167
MST1            ------------------KRNTVIGTPFWMAPEV---------------- 166
MST2            ------------------KRNTVIGTPFWMAPEV---------------- 166
MST3            ------------------KRNTFVGTPFWMAPEV---------------- 167
YSK1            ------------------KRNTFVGTPFWMAPEV---------------- 167
MST4            ------------------KRNTFVGTPFWMAPEV---------------- 167
LOK             ------------------KRDSFIGTPYWMAPEV---------------- 168
SLK             ------------------RRDSFIGTPYWMAPEV---------------- 168
MAP3K4          ------------------EVNSTLGTAAYMAPEV---------------- 171
MAP3K2          ------------------GMKSVTGTPYWMSPEV---------------- 177
MAP3K3          ------------------GMRSVTGTPYWMSPEV---------------- 177
MAP3K8          ------------------MLKSMHGTPYWMAPEV---------------- 178
MAP3K5          ------------------CTETFTGTLQYMAPEI---------------- 176
MAP3K7          ------------------CTETFTGTLQYMAPEI---------------- 167
MAP3K6          ------------------CTETFTGTLQYMAPEI---------------- 166
PAK1            ------------------KRSTMVGTPYWMAPEV---------------- 166
PAK3            ------------------KRSTMVGTPYWMAPEV---------------- 166
PAK2            ------------------KRSTMVGTPYWMAPEV---------------- 167
PAK4            ------------------RRKSLVGTPYWMAPEL---------------- 166
PAK5            ------------------KRKSLVGTPYWMAPEV---------------- 166
PAK6            ------------------KRKSLVGTPYWMAPEV---------------- 166
OSR1            ------------------VRKTFVGTPCWMAPEV---------------- 181
STLK3           ------------------VRKTFVGTPCWMAPEV---------------- 181
TAO1            --------------------NSFVGTPYWMAPEV---------------- 166
TAO3            --------------------NSFVGTPYWMAPEV---------------- 166
TAO2            -------------------ANSFVGTPYWMAPEV---------------- 166
MYO3A           ------------------RRNTSVGTPFWMAPEV---------------- 176
MYO3B           ------------------RRNTSVGTPFWMAPEV---------------- 176
ZC1/HGK         ------------------RRNTFIGTPYWMAPEV---------------- 175
ZC3/MINK        ------------------RRNTFIGTPYWMAPEV---------------- 175
ZC2/TNIK        ------------------RRNTFIGTPYWMAPEV---------------- 175
ZC4/NRK         ------------------RRNSFIGTPYWMAPEV---------------- 199
MAP3K1          ------------------FQGQLLGTIAFMAPEV---------------- 178
GAK             ----------AQRRALVEEEITRNTTPMYRTPEI---------------- 192
SGK495          ---------------LLK---DQRGSPAYISPDV---------------- 87
TRB1            ---------------ALS---DKHGCPAYVSPEI---------------- 155
TRB2            ---------------SLS---DKHGCPAYVSPEI---------------- 160
TRB3            ---------------SLW---DKHACPAYVGPEI---------------- 158
SSTK            -------------PDLST---TYCGSAAYASPEV---------------- 171
TSSK3           ------------HRELSQ---TFCGSTAYAAPEV---------------- 171
TSSK1           ----------SGRMALSK---TFCGSPAYAAPEV---------------- 175
TSSK2           ----------NGRIILSK---TFCGSAAYAAPEV---------------- 175
TSSK4           ----------NCFSHLSQ---TYCGSFAYACPEI---------------- 185
HUNK            ---------------PFS---TQCGSPAYAAPEL---------------- 174
SNRK            ---------------KLT---TSCGSLAYSAPEI---------------- 170
NIM1            ---------------MLN---TFCGSPPYAAPEL---------------- 168
MELK            -------------DYHLQ---TCCGSLAYAAPEL---------------- 169
BRSK1           ---------------LLE---TSCGSPHYACPEV---------------- 168
BRSK2           ---------------LLE---TSCGSPHYACPEV---------------- 168
MARK1           ---------------KLD---TFCGSPPYAAPEL---------------- 168
MARK2           ---------------KLD---TFCGSPPYAAPEL---------------- 168
MARK3           ---------------KLD---TFCGSPPYAAPEL---------------- 168
MARK4           ---------------KLD---TFCGSPPYAAPEL---------------- 168
QIK             ---------------LLA---TWCGSPPYAAPEV---------------- 168
SIK             ---------------PLS---TWCGSPPYAAPEV---------------- 168
QSK             ---------------LLK---TWCGSPPYAAPEL---------------- 168
AMPKA1          ---------------FLR---TSCGSPNYAAPEV---------------- 169
AMPKA2          ---------------FLR---TSCGSPNYTAPEV---------------- 169
NUAK1           ---------------FLQ---TFCGSPLYASPEI---------------- 169
NUAK2           ---------------FLQ---TFCGSPLYASPEI---------------- 168
BIKE            ----------N----VVEEEIKKYTTLSYRAPEM---------------- 184
AAK1            ----------N----AVEDEIKKYTTLSYRAPEM---------------- 185
LIMK1           E------GLRSLKKPDRKKRYTVVGNPYWMAPEM---------------- 182
LIMK2           PMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEM---------------- 187
TESK1           R----------------KEPLAVVGSPYWMAPEV---------------- 172
TESK2           E------------------KLAVVGSPFWMAPEV---------------- 150
WNK1            K--------------------SVIGTPEFMAPEM---------------- 174
WNK3            K--------------------SVIGTPEFMAPEM---------------- 174
WNK2            K--------------------SVIGTPEFMAPEM---------------- 174
WNK4            K--------------------SVIGTPEFMAPEM---------------- 174
NEK10           T--------------------SVVGTILYSCPEV---------------- 182
NEK6            H--------------------SLVGTPYYMSPER---------------- 174
NEK7            H--------------------SLVGTPYYMSPER---------------- 174
NEK2            K--------------------TFVGTPYYMSPEQ---------------- 180
NEK1            R--------------------TCIGTPYYLSPEI---------------- 171
NEK5            R--------------------TCIGTPYYLSPEI---------------- 172
NEK3            C--------------------TYVGTPYYVPPEI---------------- 170
NEK4            S--------------------TLIGTPYYMSPEL---------------- 172
NEK8            ------------------------STPCYISPEL---------------- 164
NEK9            E--------------------TLVGTPYYMSPEL---------------- 171
NRBP1           R--------------------EEQKNLHFFAPEY---------------- 183
NRBP2           R--------------------EELRNLHFFPPEY---------------- 197
CLIK1           --------------VNKYWLSSACGSDFYMAPEV---------------- 225
CLIK1L          --------------VNKCFLSTACGTDFYMAPEV---------------- 222
STK33           --------------RSEAMLQATCGTPIYMAPEV---------------- 179
DOMAIN2_GCN2    -------------------------EQTRV-------------------- 185
SCYL1           ------------------------ELEQYDPPE----------------- 160
SCYL3           -------------------------DPASIPPE----------------- 148
DOMAIN2_JAK1    ------------------------ERIPWIAPE----------------- 180
DOMAIN2_TYK2    ------------------------ERIPWLAPE----------------- 194
DOMAIN2_JAK2    ------------------------ERIPWVPPE----------------- 178
DOMAIN2_JAK3    ------------------------DRIPWVAPE----------------- 174
ILK             -------------------------APAWVAPE----------------- 167
LRRK1           ------------------------GTPGYQAPE----------------- 193
PBK             ------------------------GTEPWKPKE----------------- 185
WEE1            ------------------------GDSRFLANE----------------- 188
WEE1B           ------------------------GDSRFLANE----------------- 192
SGK071          -------------------------RKSWMAPE----------------- 178
PIK3R4          --------------------------TCYIAPERFVDGGMFATELEYMRD 192
MSSK1           ---------------------------------LGNACWVHKHFTEDIQ- 313
SRPK1           ---------------------------------LGNACWVHKHFTEDIQ- 434
SRPK2           ---------------------------------LGNACWVHKHFTEDIQ- 466
RSKL1           -------------------------ERMYCAPE----------------- 150
RSKL2           -------------------------DNLYSAPE----------------- 302
SGK396          ------------------------GDLSLMSPE----------------- 166
VRK1            ---------------------------------RYCPEGVHKEYKEDPKR 183
VRK2            ---------------------------------RYCPNGNHKQYQENPRK 180
VRK3            ---------------------------------RYCPSGKHVAYVEGSRS 128
BUB1            ------------------------ETSGFQCVE----------------- 189
BUBR1           ------------------------TLSGFRTVQ----------------- 182
SGK196          -------------------------HGDFVAPE----------------- 177
SGK493          -------------------------------------------------- 174
                                                                  

DYRK1A          --------LLGM-----------------P-YDLAIDMWSL---GCILVE 195
DYRK1B          --------LLGT-----------------P-YDLAIDMWSL---GCILVE 195
DYRK2           --------ILGA-----------------R-YGMPIDMWSL---GCILAE 193
DYRK3           --------ILGS-----------------R-YSTPIDIWSF---RCILAE 193
DYRK4           --------ILGH-----------------P-YDVAIDMWSL---GCITAE 193
HIPK1           --------ILGL-----------------P-FCEAIDMWSL---GCVIAE 195
HIPK2           --------ILGL-----------------P-FCEAIDMWSL---GCVIAE 195
HIPK3           --------ILGL-----------------P-FCEAIDMWSL---GCVIAE 195
HIPK4           --------LLGL-----------------P-FCEKVDVWSL---GCVMAE 197
PRP4            --------IIGK------------------SYDYGIDMWSV---GCTLYE 195
MOK             --------LLTD-----------------GFYTYKMDLWSA---GCVFYE 191
1A6O            --------LVDL-----------------QDYDYSLDMWSL---GCMFAG 186
1LPUA           --------LVDL-----------------QDYDYSLDMWSL---GCMFAG 186
CK2A1           --------LVDY-----------------QMYDYSLDMWSL---GCMLAS 186
CK2A1-RS        --------LVDY-----------------QMYDYSLDMWSL---GCMLAS 186
CK2A2           --------LVDY-----------------QMYDYSLDMWSL---GCMLAS 186
HSER            --------LRQA------------------NISQKGDVYSY---GIIAQE 184
SLOB            ---------------YFSQ-------FRKINTLESVDVHCF---GHLLYE 196
CDC7            --------LTKC-----------------PNQTTAIDMWSA---GVIFLS 349
1CSN            --------HLG------------------REQSRRDDLEAL---GHVFMY 199
CK1G1           --------HLG------------------KEQSRRDDLEAL---GHMFMY 200
CK1G3           --------HLG------------------KEQSRRDDLEAL---GHMFMY 199
CK1G2           --------HLG------------------KEQSRRDDLEAL---GHMFMY 199
CK1A            --------HLG------------------IEQSRRDDMESL---GYVLMY 197
CK1A2           --------HLG------------------IEQSRRDDMESL---GYVFMY 197
1CKJA           --------HLG------------------IEQSRRDDLESL---GYVLMY 197
CK1D            --------HLG------------------IEQSRRDDLESL---GYVLMY 197
CK1E            --------HLG------------------IEQSRRDDLESL---GYVLMY 197
TTBK1           --------HKN------------------REMGRHDDLWSL---FYMLVE 198
TTBK2           --------HRN------------------REMGRHDDLWSL---FYMLVE 198
TLK1            --------FVVGK--------------EPPKISNKVDVWSV---GVIFFQ 211
TLK2            --------FVVGK--------------EPPKISNKVDVWSV---GVIFYQ 212
GPRK4           --------VNN------------------EKYTFSPDWWGL---GCLIYE 192
GPRK6           --------VKN------------------ERYTFSPDWWAL---GCLLYE 192
GPRK5           --------LNN------------------QRYGLSPDYWGL---GCLIYE 192
RHOK            --------LQG------------------EEYDFSVDYFAL---GVTLYE 195
GPRK7           --------LMEK-----------------VSYSYPVDWFAM---GCSIYE 193
BARK1           --------LQKG-----------------VAYDSSADWFSL---GCMLFK 193
BARK2           --------LQKG-----------------TAYDSSADWFSL---GCMLFK 193
TTK             --------IKDMSSSRENG-------KSKSKISPKSDVWSL---GCILYY 202
RIPK1           --------LNDVN----------------AKPTEKSDVYSF---AVVLWA 204
HASPIN          --------RLMK---KENN-------NRWGEYHPYSNVLWL---HY-LTD 267
GCN2            --------QGSTK----------------SAYNQKVDLFSL---GIIFFE 346
HRI             --------LEGSE------------------YDAKSDMYSL---GVVLLE 356
KIS             --------SD-TE------------------CTSAVDLWSL---GIILLE 212
PDK1            --------LTEKS------------------ACKSSDLWAL---GCIIYQ 193
PKR             --------ISSQD------------------YGKEVDLYAL---GLILAE 214
PEK             --------IHGNS------------------YSHKVDIFSL---GLILFE 424
PRPK            ----------------------------------GVDLYVL---EKAFLS 177
DOMAIN2_OBSCN   --------LEG------------------QGAVPQTDIWAI---GVTAFI 188
DOMAIN2_SPEG    --------VKG------------------EPIGSATDIWGA---GVLTYI 188
LMR1            --------VDEVHSNLLV-----------VDQTKSGNVWSL---GVTIWE 205
LMR2            --------VTSFQDRLLT-----------ADQTKYSNIWSL---GVTLWE 205
LMR3            --------LGELHGTFMV-----------MDQSRESNIWSL---GVTLWE 210
SGK307          --------ILQ------------------KAATVKSDIYSF---SMIMQE 109
STLK5           --------LQQNL----------------QGYDAKSDIYSV---GITACE 203
STLK6           --------LRQDL----------------HGYNVKSDIYSV---GITACE 203
STLK6-RS        --------LRQDL----------------HGYNVKSDIYSV---GITACE 203
OBSCN           --------IQQ------------------NPVSEASDIWAM---GVISYL 188
SPEG            --------VNQ------------------SPVSGVTDIWPV---GVVAFL 189
TRAD            --------IQG------------------IPVSLGTDIWSI---GVLTYV 189
TRIO            --------ILG------------------NPVSLTSDTWSV---GVLTYV 189
SGK223          --------VSA------------------SQYR-KFDEFQT---GILIYE 244
SGK269          --------ITA------------------TQYK-KCDEFQT---GILIYE 216
ALK1            --------LD-EQIRTDCF----------ES-YKWTDIWAF---GLVLWE 206
ALK2            --------LD-ETIQVDCF----------DS-YKRVDIWAF---GLVLWE 206
IRAK4           --------LR-GEITP------------------KSDIYSF---GVVLLE 194
BMPR2           --------LE-GAVNLRDC----------ESALKQVDMYAL---GLIYWE 213
TGFBR2          --------LE-SRMNLENA----------ES-FKQTDVYSM---ALVLWE 213
ACTR2           --------LE-GAINFQR-----------DA-FLRIDMYAM---GLVLWE 205
ACTR2B          --------LE-GAINFQR-----------DA-FLRIDMYAM---GLVLWE 206
1B6CB           --------LD-DSINMKHF----------ES-FKRADIYAM---GLVFWE 206
TGFBR1          --------LD-DSINMKHF----------ES-FKRADIYAM---GLVFWE 206
ALK4            --------LD-ETINMKHF----------DS-FKCADIYAL---GLVYWE 206
ALK7            --------LD-DTMNVNIF----------ES-FKRADIYSV---GLVYWE 206
BMPR1A          --------LD-ESLNKNHF----------QP-YIMADIYSF---GLIIWE 206
BMPR1B          --------LD-ESLNRNHF----------QS-YIMADMYSF---GLILWE 206
IRAK1           --------IKTGRLA------------------VDTDTFSF---GVVVLE 205
IRAK2           --------IRV------------------GQLTKRVDIFSC---GIVLAE 198
IRAK3           --------IRQ------------------GKLSIKTDVYSF---GIVIME 202
MISR2           --------LDKTLDLQDW-----------GMALRRADIYSL---ALLLWE 217
MYT1            --------LQ-------------------GSYGTAADVFSL---GLTILE 189
SBK             --------CQAG--RADG-----------LAVDTGVDVWAF---GVLIFC 193
SGK110          --------CLLL--PPDT-----------LPLRPAVDSWGL---GVLLFC 192
SGK069          --------CAPP-PLPEG-----------LPIQPALDAWAL---GVLLFC 194
SGK496          --------FT-------------------GKYDNSVDVYAF---GILFWY 189
NIK             --------VLG------------------RSCDAKVDVWSS---CCMMLH 189
SGK424          -------------------------------------------------- 0
SURTK106        --------LLL------------------RPASIRADVWSF---GILLYE 205
IKKE            --------YERAVLRKPQQ----------KAFGVTVDLWSI---GVTLYH 205
TBK1            --------YERAVLRKDHQ----------KKYGATVDLWSI---GVTFYH 205
MOS             --------LK-------GE----------GVT-PKADIYSF---AITLWQ 212
LKB1            --------AN------GLD----------TFSGFKVDIWSA---GVTLYN 199
CAMKK1          --------IS-----DSGQ----------SFSGKALDVWAT---GVTLYC 226
CAMKK2          --------LS-----ETRK----------IFSGKAKDVWAM---GVTLYC 218
PASK            --------LM-------GN----------PYRGPELEMWSL---GVTLYT 197
PIM1            --------IR-------YH----------RYHGRSAAVWSL---GILLYD 197
PIM3            --------IR-------YH----------RYHGRSATVWSL---GVLLYD 198
PIM2            --------IS-------RH----------QYHALPATVWSL---GILLYD 199
COT             --------IL--------C----------RGHSTKADIYSL---GATLIH 184
SCYL2           --------IL--------S----------VSCETASDMYSL---GTVMYA 227
FUSED           --------VEERPYD------------------HTADLWSV---GCILYE 189
ULK1            --------IMSQHYD------------------GKADLWSI---GTIVYQ 198
ULK2            --------IMSQHYD------------------AKADLWSI---GTVIYQ 198
ULK3            --------VCQRQYD------------------ARVDLWSM---GVILYE 192
ULK4            --------VRGADFS------------------ISSDLWSL---GCLLYE 193
IRE1            --------LSEDCKE--N------------PT-YTVDIFSA---GCVFYY 196
IRE2            --------LQLLPPD--S------------PT-SAVDIFSA---GCVFYY 196
RNASEL          ------------PQE------------------VKRDLEDL---GRLVLY 162
MPSK1           --------FSVQSH--CV------------ID-ERTDVWSF---GCVLYA 208
PINK1           --------STARPGPRAV------------IDYSKADAWAV---GAIAYE 290
ALK             --------FM------------------EGIFTSKTDTWSF---GVLLWE 206
LTK             --------FL------------------EGIFTSKTDSWSF---GVLLWE 206
ROS             --------LM------------------DGIFTTQSDVWSF---GILIWE 209
IGF1R           --------LK------------------DGVFTTYSDVWSF---GVVLWE 206
1IR3A           --------LK------------------DGVFTTSSDMWSF---GVVLWE 206
INSR            --------LK------------------DGVFTTSSDMWSF---GVVLWE 206
IRR             --------LK------------------DGIFTTHSDVWSF---GVVLWE 206
1M14A           --------IL------------------HRIYTHQSDVWSY---GVTVWE 195
EGFR            --------IL------------------HRIYTHQSDVWSY---GVTVWE 195
HER2/ERBB2      --------IL------------------RRRFTHQSDVWSY---GVTVWE 195
HER4/ERBB4      --------IH------------------YRKFTHQSDVWSY---GVTIWE 195
HER3/ERBB3      --------IH------------------FGKYTHQSDVWSY---GVTVWE 195
ITK             --------FS------------------FSRYSSKSDVWSF---GVLMWE 188
TEC             --------FN------------------YSRFSSKSDVWSF---GVLMWE 188
TXK             --------FL------------------FNKYSSKSDVWSF---GVLMWE 188
BMX             --------FH------------------YFKYSSKSDVWAF---GILMWE 188
1K2PA           --------LM------------------YSKFSSKSDIWAF---GVLMWE 188
BTK             --------LM------------------YSKFSSKSDIWAF---GVLMWE 188
CCK4            --------IL------------------EGDFSTKSDVWAF---GVLMWE 203
ROR1            --------IM------------------YGKFSSDSDIWSF---GVVLWE 212
ROR2            --------IM------------------YGKFSIDSDIWSY---GVVLWE 212
MUSK            --------IF------------------YNRYTTESDVWAY---GVVLWE 220
TRKA            --------IL------------------YRKFTTESDVWSF---GVVLWE 210
TRKB            --------IM------------------YRKFTTESDVWSL---GVVLWE 208
TRKC            --------IM------------------YRKFTTESDVWSF---GVILWE 211
DDR1            --------IL------------------MGKFTTASDVWAF---GVTLWE 226
DDR2            --------IL------------------LGKFTTASDVWAF---GVTLWE 217
RYK             --------LV------------------NNEFSSASDVWAF---GVTLWE 205
JAK1            --------LM------------------QSKFYIASDVWSF---GVTLHE 198
JAK2            --------LT------------------ESKFSVASDVWSF---GVVLYE 198
JAK3            --------LS------------------DNIFSRQSDVWSF---GVVLYE 198
ACK             --------LK------------------TRTFSHASDTWMF---GVTLWE 197
TYK2            --------LK------------------EYKFYYASDVWSF---GVTLYE 197
TNK1            --------LR------------------HGAFSSASDVWMF---GVTLWE 200
EPHA1           --------IA------------------HRIFTTASDVWSF---GIVMWE 195
EPHA10          --------LQ------------------FGHFSSASDVWSF---GIIMWE 194
FAK             --------IN------------------FRRFTSASDVWMF---GVCMWE 193
EPHB6           --------IA------------------HGKHTTSSDVWSF---GILMWE 184
EPHA2           --------IS------------------YRKFTSASDVWSF---GIVMWE 197
EPHA8           --------IA------------------FRTFSSASDVWSF---GVVMWE 196
EPHA6           --------IA------------------YRKFSSASDAWSY---GIVMWE 238
EPHB1           --------IA------------------YRKFTSASDVWSY---GIVMWE 198
EPHB2           --------IQ------------------YRKFTSASDVWSY---GIVMWE 198
EPHB3           --------IA------------------YRKFTSASDVWSY---GIVMWE 198
EPHB4           --------IA------------------FRKFTSASDAWSY---GIVMWE 198
EPHA7           --------IQ------------------YRKFTSASDVWSY---GIVMWE 196
EPHA4           --------IA------------------YRKFTSASDVWSY---GIVMWE 196
EPHA3           --------IA------------------YRKFTSASDVWSY---GIVLWE 196
EPHA5           --------IA------------------FRKFTSASDVWSY---GIVMWE 196
PYK2            --------IN------------------FRRFTTASDVWMF---AVCMWE 193
CSK             --------LR------------------EKKFSTKSDVWSF---GILLWE 184
CTK             --------LK------------------HGKFTSKSDVWSF---GVLLWE 182
1IEPA           --------LA------------------YNKFSIKSDVWAF---GVLLWE 190
ABL             --------LA------------------YNKFSIKSDVWAF---GVLLWE 190
ARG             --------LA------------------YNTFSIKSDVWAF---GVLLWE 190
BRK             --------LS------------------RGHYSTKSDVWSF---GILLHE 189
SRM             --------AN------------------YRVFSQKSDVWSF---GVLLHE 189
FRK             --------IR------------------SNKFSIKSDVWSF---GILLYE 192
FGR             --------AL------------------FGRFTIKSDVWSF---GILLTE 188
FYN             --------AL------------------YGRFTIKSDVWSF---GILLTE 188
SRC             --------AL------------------YGRFTIKSDVWSF---GILLTE 188
YES             --------AL------------------YGRFTIKSDVWSF---GILQTE 188
HCK             --------IN------------------FGSFTIKSDVWSF---GILLME 188
LYN             --------IN------------------FGCFTIKSDVWSF---GILLYE 189
3LCK            --------IN------------------YGTFTIKSDVWSF---GILLTE 188
LCK             --------IN------------------YGTFTIKSDVWSF---GILLTE 188
BLK             --------YH------------------FGVFTIKADVWSF---GVLLME 187
FER             --------LN------------------YGRYSSESDVWSF---GILLWE 190
FES             --------LN------------------YGRYSSESDVWSF---GILLWE 192
SYK             --------IN------------------YYKFSSKSDVWSF---GVLMWE 194
ZAP70           --------IN------------------FRKFSSRSDVWSY---GVTMWE 194
FGFR1           --------LF------------------DRIYTHQSDVWSF---GVLLWE 215
FGFR2           --------LF------------------DRVYTHQSDVWSF---GVLMWE 215
FGFR3           --------LF------------------DRVYTHQSDVWSF---GVLLWE 215
FGFR4           --------LF------------------DRVYTHQSDVWSF---GILLWE 215
RET             --------LF------------------DHIYTTQSDVWSF---GVLLWE 220
TIE1            --------LN------------------YSVYTTKSDVWSF---GVLLWE 207
1FVRA           --------LN------------------YSVYTTNSDVWSY---GVLLWE 207
TIE2            --------LN------------------YSVYTTNSDVWSY---GVLLWE 207
FLT1            --------IF------------------DKIYSTKSDVWSY---GVLLWE 265
KDR             --------IF------------------DRVYTIQSDVWSF---GVLLWE 264
KDR_AVE         --------IF------------------DRVYTIQSDVWSF---GVLLWE 204
FLT4            --------IF------------------DKVYTTQSDVWSF---GVLLWE 262
FMS             --------IF------------------DCVYTVQSDVWSY---GILLWE 266
FLT3            --------LF------------------EGIYTIKSDVWSY---GILLWE 271
KIT             --------IF------------------NCVYTFESDVWSY---GIFLWE 273
PDGFRA          --------IF------------------DNLYTTLSDVWSY---GILLWE 295
PDGFRB          --------IF------------------NSLYTTLSDVWSF---GILLWE 296
MER             --------LA------------------DRVYTSKSDVWAF---GVTMWE 206
AXL             --------LA------------------DRVYTSKSDVWSF---GVTMWE 206
TYRO3           --------LA------------------DNLYTVQSDVWAF---GVTMWE 207
MET             --------LQ------------------TQKFTTKSDVWSF---GVVLWE 198
RON             --------LQ------------------TYRFTTKSDVWSF---GVLLWE 198
HH498           --------FTQCT-----------------RYTIKADVFSY---ALCLWE 195
LZK             --------IRN------------------EPVSEKVDIWSF---GVVLWE 178
DLK             --------IRN------------------EPVSEKVDIWSF---GVVLWE 178
MLK1            --------IRA------------------SMFSKGSDVWSY---GVLLWE 198
MLK3            --------IKA------------------STFSKGSDVWSF---GVLLWE 198
MLK2            --------IRL------------------SLFSKSSDVWSF---GVLLWE 198
MLK4            --------IKS------------------SLFSKGSDIWSY---GVLLWE 213
ZAK             --------IQS------------------LPVSETCDTYSY---GVVLWE 183
TAK1            --------FEG------------------SNYSEKCDVFSW---GIILWE 186
KSR1            --------VREMTPGKDED---------QLPFSKAADVYAF---GTVWYE 201
KSR2            --------IRQLSPDTEED---------KLPFSKHSDVFAL---GTIWYE 201
ARAF            --------IRMQ------D---------PNPYSFQSDVYAY---GVVLYE 192
RAF1            --------IRMQ------D---------NNPFSFQSDVYSY---GIVLYE 192
BRAF            --------IRMQ------D---------KNPYSFQSDVYAF---GIVLYE 192
LRRK2           --------ARGN-----------------VIYNQQADVYSF---GLLLYD 187
ANKRD3          --------IREKS----------------RLFDTKHDVYSF---AIVIWG 194
SGK288          --------FLESN----------------KAPGPKYDVYSF---AIVIWE 194
RIPK2           --------YEPGQ---------------KSRASIKHDIYSY---AVITWE 204
RIPK3           --------FVNVN----------------RKASTASDVYSF---GILMWA 193
MLKL            --------LEDVF----------------YQYDVKSEIYSF---GIVLWE 197
ANPA            --------LRMASP--------------PVRGSQAGDVYSF---GIILQE 197
ANPB            --------LSGNPL--------------PTTGMQKADVYSF---GIILQE 198
CYGD            --------LRDPAL--------------ERRGTLAGDVFSL---AIIMQE 206
CYGF            --------LRAPRG--------------SRLGSFAGDVYSF---AIIMQE 211
TBCK            --------IAQGIFKTTDHMPSK----KPLPSGPKSDVWSL---GIILFE 179
ERK1            --------MLNS-----------------KGYTKSIDIWSV---GCILAE 196
3ERK            --------MLNS-----------------KGYTKSIDIWSV---GCILAE 196
ERK2            --------MLNS-----------------KGYTKSIDIWSV---GCILAE 196
ERK5            --------MLSL-----------------HEYTQAIDLWSV---GCIFGE 200
1JNK            --------ILGM------------------GYKENVDIWSV---GCIMGE 187
1PMNA           --------ILGM------------------GYKENVDIWSV---GCIMGE 192
JNK3            --------ILGM------------------GYKENVDIWSV---GCIMGE 192
JNK1            --------ILGM------------------GYKENVDLWSV---GCIMGE 192
JNK2            --------ILGM------------------GYKENVDIWSV---GCIMGE 192
1P38            --------MLNW-----------------MHYNQTVDIWSV---GCIMAE 192
P38A            --------MLNW-----------------MHYNQTVDIWSV---GCIMAE 192
P38B            --------MLNW-----------------MHYNQTVDIWSV---GCIMAE 200
P38D            --------ILSW-----------------MHYNQTVDIWSV---GCIMAE 191
P38G            --------ILNW-----------------MRYTQTVDIWSV---GCIMAE 192
NLK             --------LMGS-----------------RHYSNAIDIWSV---GCIFAE 196
ERK7            --------LLSS-----------------HRYTLGVDMWSL---GCILGE 217
ERK3            --------LLSP-----------------NNYTKAIDMWAA---GCIFAE 205
ERK4            --------LLSP-----------------NNYTKAIDMWAA---GCILAE 202
ICK             --------LLRS-----------------TNYSSPIDVWAV---GCIMAE 189
MAK             --------LLRS-----------------SVYSSPIDVWAV---GSIMAE 189
PCTAIRE1        --------LLGS-----------------TDYSTQIDMWGV---GCIFYE 190
PCTAIRE2        --------LLGS-----------------SEYLTQIDMWGV---GCIFFE 190
PCTAIRE3        --------LLGS-----------------TEYSTPIDMWGV---GCIHYE 190
PFTAIRE1        --------LLGS-----------------TEYSTCLDMWGV---GCIFVE 190
PFTAIRE2        --------LLGA-----------------TEYSSELDIWGA---GCIFIE 190
CDC2            --------LLGS-----------------ARYSTPVDIWSI---GTIFAE 193
1HCL            --------LLGC-----------------KYYSTAVDIWSL---GCIFAE 188
CDK2            --------LLGC-----------------KYYSTAVDIWSL---GCIFAE 192
CDK3            --------LLGS-----------------KFYTTAVDIWSI---GCIFAE 192
CDK5            --------LFGA-----------------KLYSTSIDMWSA---GCIFAE 191
CDK7            --------LFGA-----------------RMYGVGVDMWAV---GCILAE 194
CDK4            --------LLQS-----------------T-YATPVDMWSV---GCIFAE 201
1BLXA           --------LLQS-----------------S-YATPVDLWSV---GCIFAE 199
CDK6            --------LLQS-----------------S-YATPVDLWSV---GCIFAE 199
PITSLRE         --------LLGA-----------------KEYSTAVDMWSV---GCIFGE 193
CDK10           --------LLGT-----------------TTQTTSIDMWAV---GCILAE 193
CDK9            --------LLGE-----------------RDYGPPIDLWGA---GCIMAE 203
CHED            --------LLGE-----------------ERYTPAIDVWSC---GCILGE 202
CRK7            --------LLGE-----------------ERYTPAIDVWSC---GCILGE 202
CCRK            --------LYGA-----------------RQYDQGVDLWSV---GCIMGE 193
CDK11           --------LLGA-----------------RHYTKAIDIWAI---GCIFAE 207
CDK8            --------LLGA-----------------RHYTKAIDIWAI---GCIFAE 207
IKKA            --------FE------NK-----------PY-TATVDYWSF---GTMVFE 199
IKKB            --------LE------QQ-----------KY-TVTVDYWSF---GTLAFE 200
1PHK            --------IECSMNDNHP-----------GY-GKEVDMWST---GVIMYT 203
PHKG1           --------IECSMNEDHP-----------GY-GKEVDMWST---GVIMYT 203
PHKG2           --------LKCSMDETHP-----------GY-GKEVDLWAC---GVILFT 202
CAMK2A          --------LR------KD-----------PY-GKPVDLWAC---GVILYI 193
CAMK2B          --------LR------KE-----------AY-GKPVDIWAC---GVILYI 193
CAMK2G          --------LR------KD-----------PY-GKPVDIWAC---GVILYI 193
CAMK2D          --------LR------KD-----------PY-GKPVDMWAC---GVILYI 193
CASK            --------VK------RE-----------PY-GKPVDVWGC---GVILFI 200
1IA8A           --------LK------RR-----------EFHAEPVDVWSC---GIVLTA 189
CHK1            --------LK------RR-----------EFHAEPVDVWSC---GIVLTA 192
CLK1            --------IL------AL-----------GW-SQPCDVWSI---GCILIE 211
CLK4            --------IL------AL-----------GW-SQPCDVWSI---GCILIE 210
CLK2            --------IL------EL-----------GW-SQPCDVWSI---GCIIFE 211
CLK3            --------IL------EL-----------GW-AQPCDVWSI---GCILFE 211
MAP2K5          --------I-----SG-------------EQYGIHSDVWSL---GISFME 183
MAP2K3          --------INP-ELNQ-------------KGYNVKSDVWSL---GITMIE 197
MAP2K6          --------INP-ELNQ-------------KGYSVKSDIWSL---GITMIE 197
MAP2K4          --------IDP-SASR-------------QGYDVRSDVWSL---GITLYE 198
MAP2K7          --------IDPPDPTK-------------PDYDIRADVWSL---GISLVE 195
MAP2K1          --------LQG------------------THYSVQSDIWSM---GLSLVE 188
MAP2K2          --------LQG------------------THYSVQSDIWSM---GLSLVE 188
CDKL5           --------LLG------------------APYGKSVDMWSV---GCILGE 191
CDKL1           --------LVG-----------------DTQYGPPVDVWAI---GCVFAE 191
CDKL4           --------LVG-----------------DTQYGSSVDIWAI---GCVFAE 190
CDKL2           --------LVG-----------------DVKYGKAVDVWAI---GCLVTE 191
CDKL3           --------VLK-----------------DTSYGKPVDIWAL---GCMIIE 190
1I09B           --------IFG-----------------ATDYTSSIDVWSA---GCVLAE 194
GSK3B           --------IFG-----------------ATDYTSSIDVWSA---GCVLAE 194
1J1BA           --------IFG-----------------ATDYTSSIDVWSA---GCVLAE 194
GSK3A           --------IFG-----------------ATDYTSSIDVWSA---GCVLAE 194
LATS1           ---------------EVLLRT--G-------YTQLCDWWSV---GVILFE 238
LATS2           ---------------EVLLRK--G-------YTQLCDWWSV---GVILFE 238
NDR1            ---------------EVFMQT--G-------YNKLCDWWSL---GVIMYE 226
NDR2            ---------------EVFMQT--G-------YNKLCDWWSL---GVIMYE 226
MAST1           ---------------EVILRQ--G-------YGKPVDWWAM---GIILYE 206
MAST4           ---------------EVILRQ--G-------YGKPVDWWAM---GIILYE 206
MAST2           ---------------EVILRQ--G-------YGKPVDWWAM---GIILYE 206
MAST3           ---------------EVIFRQ--G-------YGKPVDWWAM---GVVLYE 206
MRCKA           ---------------EILQAM--ED--GKGRYGPECDWWSL---GVCMYE 198
MRCKB           ---------------EILQAM--ED--GMGKYGPECDWWSL---GVCMYE 198
DMPK2           ---------------EILQAM--EE--GKGHYGPQCDWWSL---GVCAYE 198
DMPK1           ---------------EILQAV--GGGPGTGSYGPECDWWAL---GVFAYE 200
ROCK1           ---------------EVLKSQ--G---GDGYYGRECDWWSV---GVFLYE 195
ROCK2           ---------------EVLKSQ--G---GDGFYGRECDWWSV---GVFLYE 195
CRIK            ---------------EVLTVM--N-GDGKGTYGLDCDWWSV---GVIAYE 199
MASTL           --------DYSRTPGQVLSLI--S---SLGFNTPIAEKNQD---PANILS 202
1O6LA           --------LE--D----------------NDYGRAVDWWGL---GVVMYE 191
AKT2            --------LE--D----------------NDYGRAVDWWGL---GVVMYE 191
AKT1            --------LE--D----------------NDYGRAVDWWGL---GVVMYE 192
AKT3            --------LE--D----------------NDYGRAVDWWGL---GVVMYE 191
MSK1            --------VRGGD----------------SGHDKAVDWWSL---GVLMYE 199
MSK2            --------IRS-K----------------TGHGKAVDWWSL---GILLFE 198
P70S6K          --------LM--R----------------SGHNRAVDWWSL---GALMYD 195
P70S6KB         --------LV--R----------------SGHNRAVDWWSL---GALMYD 195
RSK1            --------VN--R----------------RGHTQSADWWSF---GVLMFE 193
RSK3            --------VN--R----------------QGHSHSADWWSY---GVLMFE 193
RSK2            --------VN--R----------------RGHTQSADWWSF---GVLMFE 193
RSK4            --------VN--R----------------RGHSQSADWWSY---GVLMFE 193
1FOTA           --------VS--T----------------KPYNKSIDWWSF---GILIYE 188
1CDKA           --------IL--S----------------KGYNKAVDWWAL---GVLIYE 188
PKACA           --------IL--S----------------KGYNKAVDWWAL---GVLIYE 188
PKACB           --------IL--S----------------KGYNKAVDWWAL---GVLIYE 188
PKACG           --------IL--S----------------KGYNKAVDWWAL---GVLIYE 188
PRKX            --------IQ--S----------------KGHGRAVDWWAL---GILIFE 188
PRKY            --------IQ--S----------------KGHGRAVDWWAL---GILIFE 188
PKCA            --------IA--Y----------------QPYGKSVDWWAY---GVLLYE 192
PKCB            --------IA--Y----------------QPYGKSVDWWAF---GVLLYE 192
PKCG            --------IA--Y----------------QPYGKSVDWWSF---GVLLYE 197
PKCE            --------LQ--E----------------LEYGPSVDWWAL---GVLMYE 192
PKCH            --------LQ--E----------------MLYGPAVDWWAM---GVLLYE 192
PKCD            --------LQ--G----------------LKYTFSVDWWSF---GVLLYE 192
PKCT            --------LL--G----------------QKYNHSVDWWSF---GVLLYE 192
PKCI            --------LR--G----------------EDYGFSVDWWAL---GVLMFE 192
PKCZ            --------LR--G----------------EEYGFSVDWWAL---GVLMFE 192
PKN1            --------LT--D----------------TSYTRAVDWWGL---GVLLYE 193
PKN2            --------LT--E----------------TSYTRAVDWWGL---GVLIYE 193
PKN3            --------LT--Q----------------EAYTQAVDWWAL---GVLLYE 193
SGK             --------LH--K----------------QPYDRTVDWWCL---GAVLYE 192
SGK2            --------LR--K----------------EPYDRAVDWWCL---GAVLYE 192
SGK3            --------IR--K----------------QPYDNTVDWWCL---GAVLYE 192
PKG1            --------IL--N----------------KGHDISADYWSL---GILMYE 191
PKG2            --------IL--N----------------KGHDFSVDFWSL---GILVYE 190
AURB            --------IEGR------------------MHNEKVDLWCI---GVLCYE 189
AURC            --------IEGR------------------TYDEKVDLWCI---GVLCYE 189
AURA            --------IEGR------------------MHDEKVDLWSL---GVLCYE 189
AURORA2_AVE     --------IEGR------------------MHDEKVDLWSL---GVLCYE 178
PLK1            --------LSKK------------------GHSFEVDVWSI---GCIMYT 191
PLK2            --------LNKQ------------------GHGCESDIWAL---GCVMYT 191
PLK3            --------LLRQ------------------GHGPEADVWSL---GCVMYT 191
PLK4            --------ATRS------------------AHGLESDVWSL---GCMFYT 192
NEK11           --------LKHQ------------------GYDTKSDIWSL---ACILYE 196
YANK1           --------FSS--RKG-------------AGYSFAVDWWSL---GVTAYE 193
YANK2           --------FQVYMDRG-------------PGYSYPVDWWSL---GITAYE 195
YANK3           --------FHSFVNGG-------------TGYSFEVDWWSV---GVMAYE 195
SGK494          --------LS-----G-------------GPYNHAADWWSL---GVLLFS 189
DOMAIN2_MSK1    --------LNQ------------------NGYDESCDLWSL---GVILYT 189
DOMAIN2_MSK2    --------LAQ------------------QGYDESCDLWSL---GVILYM 185
DOMAIN2_RSK1    --------LKR------------------QGYDAACDIWSL---GILLYT 189
DOMAIN2_RSK2    --------LKR------------------QGYDAACDIWSL---GVLLYT 189
DOMAIN2_RSK3    --------LKR------------------QGYDEGCDIWSL---GILLYT 189
DOMAIN2_RSK4    --------LMQ------------------QGYDAACDIWSL---GVLFYT 189
DRAK1           --------LSY------------------DPISMATDMWSI---GVLTYV 195
DRAK2           --------LNY------------------DPITTATDMWNI---GIIAYM 195
1JKSA           --------VNY------------------EPLGLEADMWSI---GVITYI 197
DAPK1           --------VNY------------------EPLGLEADMWSI---GVITYI 197
DAPK3           --------VNY------------------EPLGLEADMWSI---GVITYI 197
DAPK2           --------VNY------------------EPLGLEADMWSI---GVITYI 197
SGK085          --------VNY------------------DFVSFPTDMWSV---GVIAYM 190
CAMLCK          --------VNY------------------EFVSFPTDMWSV---GVITYM 190
SKMLCK          --------VNY------------------DQISDKTDMWSM---GVITYM 190
SMMLCK          --------INY------------------EPIGYATDMWSI---GVICYI 190
1KOBA           --------VDR------------------EPVGFYTDMWAI---GVLGYV 190
1TKIA           --------HQH------------------DVVSTATDMWSL---GTLVYV 189
TTN             --------HQH------------------DVVSTATDMWSL---GTLVYV 189
PKD1            --------LRN------------------KGYNRSLDMWSV---GVIIYV 193
PKD3            --------LRS------------------KGYNRSLDMWSV---GVIIYV 193
PKD2            --------LLN------------------QGYNRSLDMWSV---GVIMYV 193
PSKH1           --------LVR------------------KPYTNSVDMWAL---GVIAYI 192
PSKH2           --------LLR------------------KPYTSAVDMWAL---GVITYA 192
CAMK1A          --------LAQ------------------KPYSKAVDCWSI---GVIAYI 191
CAMK1D          --------LAQ------------------KPYSKAVDCWSI---GVIAYI 191
CAMK1B          --------LEQ------------------KPYGKAVDVWAL---GVISYI 190
CAMK1G          --------LAQ------------------KPYSKAVDCWSI---GVITYI 189
CAMK4           --------LRG------------------CAYGPEVDMWSV---GIITYI 188
DCAMKL1         --------IAE------------------TGYGLKVDIWAA---GVITYI 190
DCAMKL2         --------IAE------------------TGYGLKVDIWAA---GVITYI 190
DCAMKL3         --------LSE------------------KGYGLEVDMWAA---GVILYI 190
CHK2            --------LVS---------------VGTAGYNRAVDCWSL---GVILFI 200
MAPKAPK2        --------LGP------------------EKYDKSCDMWSL---GVIMYI 192
MAPKAPK3        --------LGP------------------EKYDKSCDMWSL---GVIMYI 191
MAPKAPK5        --------LEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSL---GVIIYV 212
MNK1            --------VEVF-------------TDQATFYDKRCDLWSL---GVVLYI 205
MNK2            --------VEAFS-------------EEASIYDKRCDLWSL---GVILYI 204
VACAMKL         -------------------------------------------------- 164
GCK             --------AAVE--RK-------------GGYNELCDVWAL---GITAIE 191
KHS1            --------AAVE--KN-------------GGYNQLCDIWAV---GITAIE 191
KHS2            --------AAVE--RK-------------GGYNQLCDLWAV---GITAIE 191
HPK1            --------AAVAL--K-------------GGYNELCDIWSL---GITAIE 191
MST1            --------IQ-----E-------------IGYNCVADIWSL---GITAIE 187
MST2            --------IQ-----E-------------IGYNCVADIWSL---GITSIE 187
MST3            --------IK-----Q-------------SAYDSKADIWSL---GITAIE 188
YSK1            --------IK-----Q-------------SAYDFKADIWSL---GITAIE 188
MST4            --------IQ-----Q-------------SAYDSKADIWSL---GITAIE 188
LOK             --------VMCETMKD-------------TPYDYKADIWSL---GITLIE 194
SLK             --------VMCETSKD-------------RPYDYKADVWSL---GITLIE 194
MAP3K4          --------ITRA--KG-------------EGHGRAADIWSL---GCVVIE 195
MAP3K2          --------ISG------------------QGYGRKADIWSV---ACTVVE 198
MAP3K3          --------ISG------------------EGYGRKADVWSL---GCTVVE 198
MAP3K8          --------IN-----E-------------SGYGRKSDIWSI---GCTVFE 199
MAP3K5          --------IDKG---P-------------RGYGKAADIWSL---GCTIIE 199
MAP3K7          --------IDQG---P-------------RGYGAPADIWSL---GCTIIE 190
MAP3K6          --------IDQG---P-------------RGYGKAADIWSL---GCTVIE 189
PAK1            --------VT-----R-------------KAYGPKVDIWSL---GIMAIE 187
PAK3            --------VT-----R-------------KAYGPKVDIWSL---GIMAIE 187
PAK2            --------VT-----R-------------KAYGPKVDIWSL---GIMAIE 188
PAK4            --------IS-----R-------------LPYGPEVDIWSL---GIMVIE 187
PAK5            --------IS-----R-------------LPYGTEVDIWSL---GIMVIE 187
PAK6            --------IS-----R-------------SLYATEVDIWSL---GIMVIE 187
OSR1            --------MEQ----V-------------RGYDFKADIWSF---GITAIE 203
STLK3           --------MEQ----V-------------RGYDFKADMWSF---GITAIE 203
TAO1            --------ILAM--DE-------------GQYDGKVDVWSL---GITCIE 190
TAO3            --------ILAM--DE-------------GQYDGKVDIWSL---GITCIE 190
TAO2            --------ILAM--DE-------------GQYDGKVDVWSL---GITCIE 190
MYO3A           --------IACEQQLD-------------TTYDARCDTWSL---GITAIE 202
MYO3B           --------IACEQQYD-------------SSYDARCDVWSL---GITAIE 202
ZC1/HGK         --------IACDENPD-------------ATYDYRSDLWSC---GITAIE 201
ZC3/MINK        --------IACDENPD-------------ATYDYRSDIWSL---GITAIE 201
ZC2/TNIK        --------IACDENPD-------------ATYDFKSDLWSL---GITAIE 201
ZC4/NRK         --------IDCDEDPR-------------RSYDYRSDVWSV---GITAIE 225
MAP3K1          --------LRG------------------QQYGRSCDVWSV---GCAIIE 199
GAK             --------IDLYSNFP---------------IGEKQDIWAL---GCILYL 216
SGK495          --------LSGR--PY---------------RGKPSDMWAL---GVVLFT 109
TRB1            --------LNTTG-TY---------------SGKAADVWSL---GVMLYT 178
TRB2            --------LNTSG-SY---------------SGKAADVWSL---GVMLYT 183
TRB3            --------LSSRA-SY---------------SGKAADVWSL---GVALFT 181
SSTK            --------LLGI--PY---------------DPKKYDVWSM---GVVLYV 193
TSSK3           --------LQGI--PH---------------DSKKGDVWSM---GVVLYV 193
TSSK1           --------LQGI--PY---------------QPKVYDIWSL---GVILYI 197
TSSK2           --------LQSI--PY---------------QPKVYDIWSL---GVILYI 197
TSSK4           --------LRGL--PY---------------NPFLSDTWSM---GVILYT 207
HUNK            --------LARK--KY----------------GPKIDVWSI---GVNMYA 195
SNRK            --------LLGD--EY---------------DAPAVDIWSL---GVILFM 192
NIM1            --------FRDE--HY---------------IGIYVDIWAL---GVLLYF 190
MELK            --------IQGK--SY---------------LGSEADVWSM---GILLYV 191
BRSK1           --------IKGE--KY---------------DGRRADMWSC---GVILFA 190
BRSK2           --------IRGE--KY---------------DGRKADVWSC---GVILFA 190
MARK1           --------FQGK--KY---------------DGPEVDVWSL---GVILYT 190
MARK2           --------FQGK--KY---------------DGPEVDVWSL---GVILYT 190
MARK3           --------FQGK--KY---------------DGPEVDVWSL---GVILYT 190
MARK4           --------FQGK--KY---------------DGPEVDIWSL---GVILYT 190
QIK             --------FEGQ--QY---------------EGPQLDIWSM---GVVLYV 190
SIK             --------FEGK--EY---------------EGPQLDIWSL---GVVLYV 190
QSK             --------FEGK--EY---------------DGPKVDIWSL---GVVLYV 190
AMPKA1          --------ISGR--LY---------------AGPEVDIWSS---GVILYA 191
AMPKA2          --------ISGR--LY---------------AGPEVDIWSC---GVILYA 191
NUAK1           --------VNGR--PY---------------RGPEVDSWAL---GVLLYT 191
NUAK2           --------VNGK--PY---------------TGPEVDSWSL---GVLLYI 190
BIKE            --------INLYGGKP---------------ITTKADIWAL---GCLLYK 208
AAK1            --------VNLYSGKI---------------ITTKADIWAL---GCLLYK 209
LIMK1           --------ING------------------RSYDEKVDVFSF---GIVLCE 203
LIMK2           --------LNG------------------KSYDETVDIFSF---GIVLCE 208
TESK1           --------LRG------------------ELYDEKADVFAF---GIVLCE 193
TESK2           --------LRD------------------EPYNEKADVFSY---GIILCE 171
WNK1            --------YE-------------------EKYDESVDVYAF---GMCMLE 194
WNK3            --------YE-------------------EHYDESVDVYAF---GMCMLE 194
WNK2            --------YE-------------------EHYDESVDVYAF---GMCMLE 194
WNK4            --------YE-------------------EKYDEAVDVYAF---GMCMLE 194
NEK10           --------LKS------------------EPYGEKADVWAV---GCILYQ 203
NEK6            --------IHE------------------NGYNFKSDIWSL---GCLLYE 195
NEK7            --------IHE------------------NGYNFKSDIWSL---GCLLYE 195
NEK2            --------MNR------------------MSYNEKSDIWSL---GCLLYE 201
NEK1            --------CEN------------------KPYNNKSDIWAL---GCVLYE 192
NEK5            --------CQN------------------KPYNNKTDIWSL---GCVLYE 193
NEK3            --------WEN------------------LPYNNKSDIWSL---GCILYE 191
NEK4            --------FSN------------------KPYNYKSDVWAL---GCCVYE 193
NEK8            --------CEG------------------KPYNQKSDIWAL---GCVLYE 185
NEK9            --------CQG------------------VKYNFKSDIWAV---GCVIFE 192
NRBP1           --------GEV------------------TNVTTAVDIYSF---GMCALE 204
NRBP2           --------GE-------------------VADGTAVDIFSF---GMCALE 217
CLIK1           --------WEGH-------------------YTAKADIFAL---GIIIWA 245
CLIK1L          --------WEGH-------------------YTAKADIFAL---GIIIWA 242
STK33           --------ISAH------------------DYSQQCDIWSI---GVVMYM 200
DOMAIN2_GCN2    ---------------------RFSDNALPYKTGKKGDVWRL---GLLLLS 211
SCYL1           ------------LADSS--------GRV-VREKWSADMWRL---GCLIWE 186
SCYL3           ------------EMSPEFTT-------LPECHGHARDAFSF---GTLVES 176
DOMAIN2_JAK1    ------------CVEDS------------KNLSVAADKWSF---GTTLWE 203
DOMAIN2_TYK2    ------------CLPGGA-----------NSLSTAMDKWGF---GATLLE 218
DOMAIN2_JAK2    ------------CIENP------------KNLNLATDKWSF---GTTLWE 201
DOMAIN2_JAK3    ------------CLREA------------QTLSLEADKWGF---GATVWE 197
ILK             ------------ALQKKPEDT----------NRRSADMWSF---AVLLWE 192
LRRK1           -------------IRPR------------IVYDEKVDMFSY---GMVLYE 215
PBK             ------------AVEEN------------GVITDKADIFAF---GLTLWE 208
WEE1            ------------VLQEN------------YTHLPKADIFAL---ALTVVC 211
WEE1B           ------------ILQED------------YRHLPKADIFAL---GLTIAV 215
SGK071          ------------AL--------------NFSFSQKSDIWSL---GCIILD 199
PIK3R4          PSTPLVD------LNSNQRT--------RGELKRAMDIFSA---GCVIAE 225
MSSK1           ----TRQYRAVEVLI-------------GAEYGPPADIWST---ACMAFE 343
SRPK1           ----TRQYRSLEVLI-------------GSGYNTPADIWST---ACMAFE 464
SRPK2           ----TRQYRSIEVLI-------------GAGYSTPADIWST---ACMAFE 496
RSKL1           -------------VGAI------------TEETEACDWWSL---GAVLFE 172
RSKL2           -------------VGGI------------SELTEACDWWSF---GSLLYE 324
SGK396          -------------LKMG------------KPASPGSDLYAY---GCLLLW 188
VRK1            CHDGTIEFTSIDA-HNGV------------APSRRGDLEIL---GYCMIQ 217
VRK2            GHNGTIEFTSLDA-HKGV------------ALSRRSDVEIL---GYCMLR 214
VRK3            PHEGDLEFISMDL-HKG------------CGPSRRSDLQSL---GYCMLK 162
BUB1            -------------MLSN------------KPWNYQIDYFGV---AATVYC 211
BUBR1           -------------ILEGQKIL------ANCSSPYQVDLFGI---ADLAHL 210
SGK196          ------------QLWPYGEDVPFHDDLMP-SYDEKIDIWKIPDISSFLLG 214
SGK493          --------------------------------EFPARNFTL---PCSAQG 189
                                                                  

DYRK1A          MH--TGE-PLFSGANEVDQ--MNKIVEVLGIPP----------------- 223
DYRK1B          MH--TGE-PLFSGSNEVDQ--MNRIVEVLGIPP----------------- 223
DYRK2           LL--TGY-PLLPGEDEGDQ--LACMIELLGMPS----------------- 221
DYRK3           LL--TGQ-PLFPGEDEGDQ--LACMMELLGMPP----------------- 221
DYRK4           LY--TGY-PLFPGENEVEQ--LACIMEVLGLPP----------------- 221
HIPK1           LF--LGW-PLYPGASEYDQ--IRYISQTQGLPA----------------- 223
HIPK2           LF--LGW-PLYPGDSEYDQ--IRYISQTQGLPA----------------- 223
HIPK3           LF--LGW-PLYPGALEYDQ--IRYISQTQGLPG----------------- 223
HIPK4           LH--LGW-PLYPGNNEYDQ--VRYICETQGLPK----------------- 225
PRP4            LY--TGK-ILFPGKTNNHM--LKLAMDLKGKMP----------------- 223
MOK             IA--SLQ-PLFPGVNELDQ--ISKIHDVIGTPA----------------- 219
1A6O            MIF-RKE-PFFYGHDNHDQ--LVKIAKVLGTDG----------------- 215
1LPUA           MIF-RKE-PFFYGHDNHDQ--LVKIAKVLGTDG----------------- 215
CK2A1           MIF-RKE-PFFHGHDNYDQ--LVRIAKVLGTED----------------- 215
CK2A1-RS        MIF-RKE-PFFHGRDNYDQ--LVRIAKVLGTED----------------- 215
CK2A2           MIF-RRE-PFFHGQDNYDQ--LVRIAKVLGTEE----------------- 215
HSER            IIL-RKE-TFYTLS-CRDR--NEKIFRVENSN------------------ 211
SLOB            MTY-GRP-PDSVPVDSFP-------------------------------- 212
CDC7            LLS-GRY-PFYKASDDLTA--LAQIMTIRGSRETIQAAKTFGKSILCSKE 395
1CSN            FLR-GSL-PWQGLKAATNKQKYERIGEKKQSTP----------------- 230
CK1G1           FLR-GSL-PWQGLKADTLKERYQKIGDTKRNTP----------------- 231
CK1G3           FLR-GSL-PWQGLKADTLKERYQKIGDTKRATP----------------- 230
CK1G2           FLR-GSL-PWQGLKADTLKERYQKIGDTKRATP----------------- 230
CK1A            FNR-TSL-PWQGLKAATKKQKYEKISEKKMSTP----------------- 228
CK1A2           FNR-TSL-PWQGLRAMTKKQKYEKISEKKMSTP----------------- 228
1CKJA           FNL-GSL-PWQGLKAATKRQKYERISEKKMSTP----------------- 228
CK1D            FNL-GSL-PWQGLKAATKRQKYERISEKKMSTP----------------- 228
CK1E            FNL-GSL-PWQGLKAATKRQKYERISEKKMSTP----------------- 228
TTBK1           FAV-GQL-PWRKIKDK------EQVGMIKEKYE----------------- 223
TTBK2           FVV-GQL-PWRKIKDK------EQVGSIKERYD----------------- 223
TLK1            CLY-GRK-PFGHNQSQQDILQENTILKA---------------------- 237
TLK2            CLY-GRK-PFGHNQSQQDILQENTILKA---------------------- 238
GPRK4           MIQ-GHS-PFKKYKEKVKWEEVDQR---IKN------------------- 218
GPRK6           MIA-GQS-PFQQRKKKIKREEVERL---VKE------------------- 218
GPRK5           MIE-GQS-PFRGRKEKVKREEVDRR---VLE------------------- 218
RHOK            MIA-ARG-PFRARGEKVENKELKHR---IIS------------------- 221
GPRK7           MVA-GRT-PFKDYKEKVSKEDLKQR---TLQ------------------- 219
BARK1           LLR-GHS-PFRQHKTKDK-HEIDRM---TLT------------------- 218
BARK2           LLR-GHS-PFRQHKTKDK-HEIDRM---TLT------------------- 218
TTK             MTY-GKT-PFQQIINQISK--LHAIID----------------------P 226
RIPK1           IFA-NKE-PYENAICEQQL---IMCIKSGNRPDV---------------- 233
HASPIN          KML-KQM-TFKTKCNT----------------PAMKQIK----------- 288
GCN2            MSYHPM--VTASE-RIFVLNQLRDPTS-PK-------------------- 372
HRI             L-FQPF--GTEME-RAEVLTGLRTG----Q-------------------- 378
KIS             M-FSGM--KLKHTVRSQEWKANSSAI------------------------ 235
PDK1            L-VAGL--PPFRA-GNEYLIFQKIIKLEYD-------------------- 219
PKR             L-LHVC--DTAFE-TSKFFTDLRDG----I-------------------- 236
PEK             L-LYPF--STQME-RVRTLTDVRNL----K-------------------- 446
PRPK            T-HPNT--ETVFEAFLK----------SYS-------------------- 194
DOMAIN2_OBSCN   MLS-AEY-PVSSEGARDLQRGLRK-GLV---------------------- 213
DOMAIN2_SPEG    MLS-GRS-PFYEPDPQETEARIVG-GRF---------------------- 213
LMR1            LFELGTQ-PYPQHSDQQVLAYTVREQQL---------------------- 232
LMR2            LFDNAAQ-PYSNLSNLDVLNQVIRERDT---------------------- 232
LMR3            LFEFGAQ-PYRHLSDEEVLAFVVRQQHV---------------------- 237
SGK307          ILT-DDI-PWKGLDGSVVKKAVVS-GNY-------------------LEA 137
STLK5           LAN-GHV-PFKDMPATQMLLEKLN-GTVPCLLDTSTIPAEE-LTMSPSRS 249
STLK6           LAS-GQV-PFQDMHRTQMLLQKLK-GPPYSPLDISIFPQSE-SRMKNSQS 249
STLK6-RS        LAS-GQV-PFQDMHRTQMLLQKLK-GPPYSPLDISIFPQSE-SRMKNSRS 249
OBSCN           SLT-CSS-PFAGESDRATLLNVLE-GRV---------------------- 213
SPEG            CLT-GIS-PFVGENDRTTLMNIRN-YNV---------------------- 214
TRAD            MLS-GVS-PFLDESKEETCINVCR-VDF---------------------- 214
TRIO            LLS-GVS-PFLDDSVEETCLNICR-LDF---------------------- 214
SGK223          LLH-QPN-PFEVRA-QLRERDYRQ-------------------------- 265
SGK269          MLH-LPN-PFDENP-ELKEREYTR-------------------------- 237
ALK1            IARRTI--V---NGIVEDYRP--PFYDVVPNDP----------------- 232
ALK2            VARRMV--S---NGIVEDYKP--PFYDVVPNDP----------------- 232
IRAK4           IITGLP--AVD---EHREPQLLLDIKEEIEDE------------------ 221
BMPR2           IFMRCT--DLFPGESVPEYQM--AFQTEVGNHP----------------- 242
TGFBR2          MTSRCN--A---VGEVKDYEP--PFGSKVREHP----------------- 239
ACTR2           LASRCT--A--ADGPVDEYML--PFEEEIGQHP----------------- 232
ACTR2B          LVSRCK--A--ADGPVDEYML--PFEEEIGQHP----------------- 233
1B6CB           IARRCS--I---GGIHEDYQL--PYYDLVPSDP----------------- 232
TGFBR1          IARRCS--I---GGIHEDYQL--PYYDLVPSDP----------------- 232
ALK4            IARRCN--S---GGVHEEYQL--PYYDLVPSDP----------------- 232
ALK7            IARRCS--V---GGIVEEYQL--PYYDMVPSDP----------------- 232
BMPR1A          MARRCI--T---GGIVEEYQL--PYYNMVPSDP----------------- 232
BMPR1B          VARRCV--S---GGIVEEYQL--PYHDLVPSDP----------------- 232
IRAK1           TLAGQR--AVKTHGARTKY--LKDLVEEEAEEAGVALRSTQS-------- 243
IRAK2           VLT-GIP-AMDNNR-SPVYLKDLLLSEIPSSTASLCSRKTGVE------- 238
IRAK3           VLT-GCR-VVLDDP-KHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPR- 248
MISR2           ILS-RCP-D----------------------------------------L 225
MYT1            VAC-NME-LPHGGE-GWQQLRQGYLP------------------------ 212
SBK             VLT-GNF-PWEAASGA---------------------------------- 207
SGK110          AAT-ACF-PWDVALAP---------------------------------- 206
SGK069          LLT-GYF-PWDRPLAEA--------------------------------- 209
SGK496          ICS-GSV-KLPEAFER---------------------------------- 203
NIK             MLN-GCH-PWTQFFRGPLCLKIASEPPPVREIPPSCAPLTAQAIQ----- 232
SGK424          -------------------------------------------------- 0
SURTK106        MVT-LGA-PPYPEVP-PTSILEHLQRRKIMKRPSSCTHTMYSIMKSCWRW 252
IKKE            AAT-GSL-PFIPFGGPRRNKEIMYRITTEKPAGAIAGAQRRENGPLE--- 250
TBK1            AAT-GSL-PFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPID--- 250
MOS             MTT-KQA-PYSGERQHILYAVVAYDLR-----PSLSAAVFE--------- 246
LKB1            ITT-GLY-PFEGDNIYKLFENI-------------------GKGSY---- 224
CAMKK1          FVY-GKC-PFIDDFILALHRKI-------------------KNEPV---- 251
CAMKK2          FVF-GQC-PFMDERIMCLHSKI-------------------KSQAL---- 243
PASK            LVF-EEN-PFCEL------EET-------------------VEAAI---- 216
PIM1            MVC-GDI-PFEHD------EEI-------------------IRGQV---- 216
PIM3            MVC-GDI-PFEQD------EEI-------------------LRGRL---- 217
PIM2            MVC-GDI-PFERD------QEI-------------------LEAEL---- 218
COT             MQT-GTP-PWVKRYPRSAYPSYLYIIH-----KQAPPLEDI--------- 218
SCYL2           VFN-KGK-PIFEVNKQDIYKSFSRQLD-----QLSRLGSSS--------- 261
FUSED           LAV-GTP-PFYATSIFQLVSLIL--------------------------- 210
ULK1            CLT-GKA-PFQASSPQDLRLFYE--------------------------- 219
ULK2            CLV-GKP-PFQANSPQDLRMFYE--------------------------- 219
ULK3            ALF-GQP-PFASRSFSELEEKIR--------------------------- 213
ULK4            MFS-GKP-PFFSESVSELTEKIL--------------------------- 214
IRE1            VVSEGSH-PFGKSLQRQANILLG--------------------------- 218
IRE2            VLSGGSH-PFGDSLYRQANILTG--------------------------- 218
RNASEL          VVKKGSI-SFEDLKAQSNEEVVQ--------------------------- 184
MPSK1           MMF-GEG-PYDMVFQKGDSVALA--------------------------- 229
PINK1           IFG-LVN-PFYGQGKAHLESRSY--------------------------- 311
ALK             IFSLGY-MPYPSKSNQEVLEFV----TS---------------------- 229
LTK             IFSLGY-MPYPGRTNQEVLDFV----VG---------------------- 229
ROS             ILTLGH-QPYPAHSNLDVLNYV----QT---------------------- 232
IGF1R           IATLAE-QPYQGLSNEQVLRFV----ME---------------------- 229
1IR3A           ITSLAE-QPYQGLSNEQVLKFV----MD---------------------- 229
INSR            ITSLAE-QPYQGLSNEQVLKFV----MD---------------------- 229
IRR             IVTLAE-QPYQGLSNEQVLKFV----MD---------------------- 229
1M14A           LMTFGS-KPYDGIPASEISSIL----EK---------------------- 218
EGFR            LMTFGS-KPYDGIPASEISSIL----EK---------------------- 218
HER2/ERBB2      LMTFGA-KPYDGIPAREIPDLL----EK---------------------- 218
HER4/ERBB4      LMTFGG-KPYDGIPTREIPDLL----EK---------------------- 218
HER3/ERBB3      LMTFGA-EPYAGLRLAEVPDLL----EK---------------------- 218
ITK             VFSEGK-IPYENRSNSEVVEDI----ST---------------------- 211
TEC             VFTEGR-MPFEKYTNYEVVTMV----TR---------------------- 211
TXK             VFTEGK-MPFENKSNLQVVEAI----SE---------------------- 211
BMX             VFSLGK-QPYDLYDNSQVVLKV----SQ---------------------- 211
1K2PA           IYSLGK-MPYERFTNSETAEHI----AQ---------------------- 211
BTK             IYSLGK-MPYERFTNSETAEHI----AQ---------------------- 211
CCK4            VFTHGE-MPHGGQADDEVLADL----QA---------------------- 226
ROR1            IFSFGL-QPYYGFSNQEVIEMV----RK---------------------- 235
ROR2            VFSYGL-QPYCGYSNQDVVEMI----RN---------------------- 235
MUSK            IFSYGL-QPYYGMAHEEVIYYV----RD---------------------- 243
TRKA            IFTYGK-QPWYQLSNTEAIDCI----TQ---------------------- 233
TRKB            IFTYGK-QPWYQLSNNEVIECI----TQ---------------------- 231
TRKC            IFTYGK-QPWFQLSNTEVIECI----TQ---------------------- 234
DDR1            VLMLCRAQPFGQLTDEQVIENAGEFFRD---------------------- 254
DDR2            TFTFCQEQPYSQLSDEQVIENTGEFFRD---------------------- 245
RYK             LMTLGQ-TPYVDIDPFEMAAYL----KD---------------------- 228
JAK1            LLTYCD-SDSSPMALFLKMI-GP-THGQMTVTRL---------------- 229
JAK2            LFTYIE-KSKSPPAEFMRMI-GNDKQGQMIVFHL---------------- 230
JAK3            LFTYCD-KSCSPSAEFLRMM-GC-ERDVPALCRL---------------- 229
ACK             MFTYGQ-E---P------WI-GL-NGSQI----L---------------- 215
TYK2            LLTHCD-SSQSPPTKFLELI-GI-AQGQMTVLRL---------------- 228
TNK1            MFSGGE-EPWPGVPPYL----------------I---------------- 217
EPHA1           VLSFGDK-PYGEMSNQEVMKS----------------------------- 215
EPHA10          VMAFGER-PYWDMSGQDVIKA----------------------------- 214
FAK             ILMHGVK-PFQGVKNNDVIGR----------------------------- 213
EPHB6           VMSYGER-PYWDMSEQEVLNA----------------------------- 204
EPHA2           VMTYGER-PYWELSNHEVMKA----------------------------- 217
EPHA8           VLAYGER-PYWNMTNRDVISS----------------------------- 216
EPHA6           VMSYGER-PYWEMSNQDVILS----------------------------- 258
EPHB1           VMSFGER-PYWDMSNQDVINA----------------------------- 218
EPHB2           VMSYGER-PYWDMTNQDVINA----------------------------- 218
EPHB3           VMSYGER-PYWDMSNQDVINA----------------------------- 218
EPHB4           VMSFGER-PYWDMSNQDVINA----------------------------- 218
EPHA7           VMSYGER-PYWDMSNQDVIKA----------------------------- 216
EPHA4           VMSYGER-PYWDMSNQDVIKA----------------------------- 216
EPHA3           VMSYGER-PYWEMSNQDVIKA----------------------------- 216
EPHA5           VVSYGER-PYWEMTNQDVIKA----------------------------- 216
PYK2            ILSFGKQ-PFFWLENKDVIGV----------------------------- 213
CSK             IYSFGRV-PYPRIPLKDVVPR----------------------------- 204
CTK             VFSYGRA-PYPKMSLKEVSEA----------------------------- 202
1IEPA           IATYGMS-PYPGIDLSQVYEL----------------------------- 210
ABL             IATYGMS-PYPGIDLSQVYEL----------------------------- 210
ARG             IATYGMS-PYPGIDLSQVYDL----------------------------- 210
BRK             MFSRGQV-PYPGMSNHEAFLR----------------------------- 209
SRM             VFTYGQC-PYEGMTNHETLQQ----------------------------- 209
FRK             IITYGKM-PYSGMTGAQVIQM----------------------------- 212
FGR             LITKGRI-PYPGMNKREVLEQ----------------------------- 208
FYN             LVTKGRV-PYPGMNNREVLEQ----------------------------- 208
SRC             LTTKGRV-PYPGMVNREVLDQ----------------------------- 208
YES             LVTKGRV-PYPGMVNREVLEQ----------------------------- 208
HCK             IVTYGRI-PYPGMSNPEVIRA----------------------------- 208
LYN             IVTYGKI-PYPGRTNADVMTA----------------------------- 209
3LCK            IVTHGRI-PYPGMTNPEVIQN----------------------------- 208
LCK             IVTHGRI-PYPGMTNPEVIQN----------------------------- 208
BLK             VVTYGRV-PYPGMSNPEVIRN----------------------------- 207
FER             TFSLGVC-PYPGMTNQQAREQ----------------------------- 210
FES             TFSLGAS-PYPNLSNQQTREF----------------------------- 212
SYK             AFSYGQK-PYRGMKGSEVTAM----------------------------- 214
ZAP70           ALSYGQK-PYKKMKGPEVMAF----------------------------- 214
FGFR1           IFTLGGS-PYPGVPVEELF-KL---------------------------- 235
FGFR2           IFTLGGS-PYPGIPVEELF-KL---------------------------- 235
FGFR3           IFTLGGS-PYPGIPVEELF-KL---------------------------- 235
FGFR4           IFTLGGS-PYPGIPVEELF-SL---------------------------- 235
RET             IVTLGGN-PYPGIPPERL-FNL---------------------------- 240
TIE1            IVSLGGT-PYCGMTCAEL-YEK---------------------------- 227
1FVRA           IVSLGGT-PYCGMTCAEL-YEK---------------------------- 227
TIE2            IVSLGGT-PYCGMTCAEL-YEK---------------------------- 227
FLT1            IFSLGGS-PYPGVQMDEDFCSR---------------------------- 286
KDR             IFSLGAS-PYPGVKIDEEFCRR---------------------------- 285
KDR_AVE         IFSLGAS-PYPGVKIDEEFCRR---------------------------- 225
FLT4            IFSLGAS-PYPGVQINEEFCQR---------------------------- 283
FMS             IFSLGLN-PYPGILVNSKFYKL---------------------------- 287
FLT3            IFSLGVN-PYPGIPVDANFYKL---------------------------- 292
KIT             LFSLGSS-PYPGMPVDSKFYKM---------------------------- 294
PDGFRA          IFSLGGT-PYPGMMVDSTFYNK---------------------------- 316
PDGFRB          IFTLGGT-PYPELPMNEQFYNA---------------------------- 317
MER             IRTRGMT-PYPGVQNHEM-YDY---------------------------- 226
AXL             IATRGQT-PYPGVENSEI-YDY---------------------------- 226
TYRO3           IMTRGQT-PYAGIENAEI-YNY---------------------------- 227
MET             LMTRGAP-PYPDVNTFDI-TVY---------------------------- 218
RON             LLTRGAP-PYRHIDPFDL-THF---------------------------- 218
HH498           ILTGE--IPFAH--LKPA--AAAA-------------------------- 213
LZK             LLTGE--IPYKD--VDSS--AIIW-------------------------- 196
DLK             LLTGE--IPYKD--VDSS--AIIW-------------------------- 196
MLK1            LLTGE--VPFRG--IDGL--AVAY-------------------------- 216
MLK3            LLTGE--VPYRG--IDCL--AVAY-------------------------- 216
MLK2            LLTGE--VPYRE--IDAL--AVAY-------------------------- 216
MLK4            LLTGE--VPYRG--IDGL--AVAY-------------------------- 231
ZAK             MLTRE--VPFKG--LEGL--QVAW-------------------------- 201
TAK1            VITRR--KPFDE--IGGPAFRIMW-------------------------- 206
KSR1            LQARD--WPLKN--QAAE--ASIW-------------------------- 219
KSR2            LHARE--WPFKT--QPA--EAIIW-------------------------- 219
ARAF            LMTGS--LPYSH--IGCR-DQIIF-------------------------- 211
RAF1            LMTGE--LPYSH--INNR-DQIIF-------------------------- 211
BRAF            LMTGQ--LPYSN--INNR-DQIIF-------------------------- 211
LRRK2           ILTTGG-RIV--EGLKF-PNEFDE-------------------------- 207
ANKRD3          VLTQK--KPFAD--EKNI-LHIMV-------------------------- 213
SGK288          LLTQK--KPYSG--FNM--MMIII-------------------------- 212
RIPK2           VLSRK--QPFED--VTN-PLQIMY-------------------------- 223
RIPK3           VLAGR--EVELP--TE--PSLVYE-------------------------- 211
MLKL            IATGD--IPFQG--CNSE--KIRK-------------------------- 215
ANPA            IALRS--GVFHVEGLDLSPKEIIE-------------------------- 219
ANPB            IALRS--GPFYLEGLDLSPKEIVQ-------------------------- 220
CYGD            VVCRS--APYAM--LELTPEEVVQ-------------------------- 226
CYGF            VMVRG--TPFCM--MDLPAQEIIN-------------------------- 231
TBCK            LCV-GRK-LFQSLDISERLKFLLTLDCVDDTLIVL--------------- 212
ERK1            MLS--NR-PIFPGKHY---------LDQLNHILGILGSPSQEDLNCIINM 234
3ERK            MLS--NR-PIFPGKHY---------LDQLNHILGILGSPSQEDLNCIINL 234
ERK2            MLS--NR-PIFPGKHY---------LDQLNHILGILGSPSQEDLNCIINL 234
ERK5            MLA--RR-QLFPGKNY---------VHQLQLIMMVLGTPSPAVIQAVGAE 238
1JNK            MVR--HK-ILFPGRDY---------IDQWNKVIEQLGTPCPEFMKKLQP- 224
1PMNA           MVR--HK-ILFPGRDY---------IDQWNKVIEQLGTPCPEFMKKLQP- 229
JNK3            MVR--HK-ILFPGRDY---------IDQWNKVIEQLGTPCPEFMKKLQP- 229
JNK1            MVC--HK-ILFPGRDY---------IDQWNKVIEQLGTPCPEFMKKLQP- 229
JNK2            LVK--GC-VIFQGTDH---------IDQWNKVIEQLGTPSAEFMKKLQP- 229
1P38            LLT--GR-TLFPGTDH---------IDQLKLILRLVGTPGAELLKKISSE 230
P38A            LLT--GR-TLFPGTDH---------INQLQQIMRLTGTPPAYLINRMPSH 230
P38B            LLQ--GK-ALFPGSDY---------IDQLKRIMEVVGTPSPEVLAKISSE 238
P38D            MLT--GK-TLFKGKDY---------LDQLTQILKVTGVPGTEFVQKLNDK 229
P38G            MIT--GK-TLFKGSDH---------LDQLKEIMKVTGTPPAEFVQRLQSD 230
NLK             LLG--RR-ILFQAQSP---------IQQLDLITDLLGTPSLEAMRTACEG 234
ERK7            MLR--GR-PLFPGTST---------LHQLELILETIPPPSEEDLLALGSG 255
ERK3            MLT--GK-TLFAGAHE---------LEQMQLILESIPVVHEEDRQELLSV 243
ERK4            MLT--GR-MLFAGAHE---------LEQMQLILETIPVIREEDKDELLRV 240
ICK             VYT--LR-PLFPGASE---------IDTIFKICQVLGTPKKTDWPEGYQL 227
MAK             LYM--LR-PLFPGTSE---------VDEIFKICQVLGTPKKSDWPEGYQL 227
PCTAIRE1        MAT--GR-PLFPGSTV---------EEQLHFIFRILGTPTEETWPGILSN 228
PCTAIRE2        MAS--GR-PLFPGSTV---------EDELHLIFRLLGTPSQETWPGISSN 228
PCTAIRE3        MAT--GR-PLFPGSTV---------KEELHLIFRLLGTPTEETWPGVTAF 228
PFTAIRE1        MIQ--GV-AAFPGMKDI--------QDQLERIFLVLGTPNEDTWPGVHSL 229
PFTAIRE2        MFQ--GQ-PLFPGVSNI--------LEQLEKIWEVLGVPTEDTWPGVSKL 229
CDC2            LAT--KK-PLFHGDSE---------IDQLFRIFRALGTPNNEVWPEVESL 231
1HCL            MVT--RR-ALFPGDSE---------IDQLFRIFRTLGTPDEVVWPGVTSM 226
CDK2            MVT--RR-ALFPGDSE---------IDQLFRIFRTLGTPDEVVWPGVTSM 230
CDK3            MVT--RK-ALFPGDSE---------IDQLFRIFRMLGTPSEDTWPGVTQL 230
CDK5            LAN-AGR-PLFPGNDV---------DDQLKRIFRLLGTPTEEQWPSMTKL 230
CDK7            LLL--RV-PFLPGDSD---------LDQLTRIFETLGTPTEEQWPDMCSL 232
CDK4            MFR--RK-PLFCGNSE---------ADQLGKIFDLIGLPPEDDWPRDVSL 239
1BLXA           MFR--RK-PLFRGSSD---------VDQLGKILDVIGLPGEEDWPRDVAL 237
CDK6            MFR--RK-PLFRGSSD---------VDQLGKILDVIGLPGEEDWPRDVAL 237
PITSLRE         LLT--QK-PLFPGKSE---------IDQINKVFKDLGTPSEKIWPGYSEL 231
CDK10           LLA--HR-PLLPGTSE---------IHQIDLIVQLLGTPSENIWPGFSKL 231
CDK9            MWT--RS-PIMQANTE---------QHQLALISQLCGSITPEVWPNVDNY 241
CHED            LFT--KK-PIFQANQE---------LAQLELISRICGSPCPAVWPDVIKL 240
CRK7            LFT--KK-PIFQANLE---------LAQLELISRLCGSPCPAVWPDVIKL 240
CCRK            LLN--GS-PLFPGKND---------IEQLCYVLRILGTPNPQVWPELTEL 231
CDK11           LLT--SE-PIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKM 254
CDK8            LLT--SE-PIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKM 254
IKKA            CIA-GYR-PFLHH---LQPFTW---------HEKIKKKDPKCIFACEEMS 235
IKKB            CIT-GFR-PFLPN---WQPVQW---------HSKVRQKSEVDIVVSEDLN 236
1PHK            LLA-GSP-PFWHR---KQMLMLRMI-----------------------MS 225
PHKG1           LLA-GSP-PFWHR---KQMLMLRMI-----------------------MS 225
PHKG2           LLA-GSP-PFWHR---RQILMLRMI-----------------------ME 224
CAMK2A          LLV-GYP-PFWDE---DQHRLYQQI-----------------------KA 215
CAMK2B          LLV-GYP-PFWDE---DQHKLYQQI-----------------------KA 215
CAMK2G          LLV-GYP-PFWDE---DQHKLYQQI-----------------------KA 215
CAMK2D          LLV-GYP-PFWDE---DQHRLYQQI-----------------------KA 215
CASK            LLS-GCL-PFYGT---KERL-FEGI-----------------------IK 221
1IA8A           MLA-GEL-PWDQP---SDSCQEYSD-----------------------WK 211
CHK1            MLA-GEL-PWDQP---SDSCQEYSD-----------------------WK 214
CLK1            YYL-GFT-VFPTHDSKEHLAMMERILGPLPKHMIQKTRK----------R 249
CLK4            YYL-GFT-VFQTHDSKEHLAMMERILGPIPQHMIQKTRK----------R 248
CLK2            YYV-GFT-LFQTHDNREHLAMMERILGPIPSRMIRKTRK----------Q 249
CLK3            YYR-GFT-LFQTHENREHLVMMEKILGPIPSHMIHRTRK----------Q 249
MAP2K5          IQK-NQG-SLM--------------------------------------- 192
MAP2K3          MAI-LRF-PYESWG------------------------------------ 209
MAP2K6          LAI-LRF-PYDSWG------------------------------------ 209
MAP2K4          LAT-GRF-PYPKWN------------------------------------ 210
MAP2K7          LAT-GQF-PYKNCK------------------------------------ 207
MAP2K1          MAV-GRY-PIPPPDAKELELMFGCQV----EGDAAETPPRPRTPGRPLSS 232
MAP2K2          LAV-GRY-PIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSG 236
CDKL5           LSD-GQP-LFPGESEIDQLFTIQKVLGPLPSEQMKLFYS----------- 228
CDKL1           LLS-GVP-LWPGKSDVDQLYLIRKTLGDLIPRHQQVFST----------- 228
CDKL4           LLT-GQP-LWPGKSDVDQLYLIIRTLGKLIPRHQSIFKS----------- 227
CDKL2           MFM-GEP-LFPGDSDIDQLYHIMMCLGNLIPRHQELFNK----------- 228
CDKL3           MAT-GNP-YLPSSSDLDLLHKIVLKVGNLSPHLQNIFSK----------- 227
1I09B           LLL-GQP-IFPGDSGVDQLVEIIKVLGT--PTREQIREM----------- 229
GSK3B           LLL-GQP-IFPGDSGVDQLVEIIKVLGT--PTREQIREM----------- 229
1J1BA           LLL-GQP-IFPGDSGVDQLVEIIKVLGT--PTREQIREM----------- 229
GSK3A           LLL-GQP-IFPGDSGVDQLVEIIKVLGT--PTREQIREM----------- 229
LATS1           MLV-GQP-PFLAQTPLETQMKVINWQTSLHI------------------- 267
LATS2           MLV-GQP-PFLAPTPTETQLKVINWENTLHI------------------- 267
NDR1            MLI-GYP-PFCSETPQETYKKVMNWKETLTF------------------- 255
NDR2            MLI-GYP-PFCSETPQETYRKVMNWKETLVF------------------- 255
MAST1           FLV-GCV-PFFGDTPEELFGQVIS--DDILW------------------- 233
MAST4           FLV-GCV-PFFGDTPEELFGQVIS--DEINW------------------- 233
MAST2           FLV-GCV-PFFGDTPEELFGQVIS--DEIVW------------------- 233
MAST3           FLV-GCV-PFFGDTPEELFGQVVS--DEIMW------------------- 233
MRCKA           MLY-GET-PFYAESLVETYGKIMNHKERFQF------------------- 227
MRCKB           MLY-GET-PFYAESLVETYGKIMNHEERFQF------------------- 227
DMPK2           LLF-GET-PFYAESLVETYGKIMNHEDHLQF------------------- 227
DMPK1           MFY-GQT-PFYADSTAETYGKIVHYKEHLSL------------------- 229
ROCK1           MLV-GDT-PFYADSLVGTYSKIMNHKNSLTF------------------- 224
ROCK2           MLV-GDT-PFYADSLVGTYSKIMDHKNSLCF------------------- 224
CRIK            MIY-GRS-PFAEGTSARTFNNIMNFQRFLKF------------------- 228
MASTL           ACL-SET-SQLSQGLVCPMS--VDQKDTT--------------------- 227
1O6LA           MMC-GRL-PFYN---------QDHE----RLFELI--------------- 211
AKT2            MMC-GRL-PFYN---------QDHE----RLFELI--------------- 211
AKT1            MMC-GRL-PFYN---------QDHE----KLFELI--------------- 212
AKT3            MMC-GRL-PFYN---------QDHE----KLFELI--------------- 211
MSK1            LLT-GAS-PFTV---------DGEKNSQAEISRRI--------------- 223
MSK2            LLT-GAS-PFTL---------EGERNTQAEVSRRI--------------- 222
P70S6K          MLT-GAP-PFTG---------ENRK----KTIDKI--------------- 215
P70S6KB         MLT-GSP-PFTA---------ENRK----KTMDKI--------------- 215
RSK1            MLT-GSL-PFQG---------KDRK----ETMALI--------------- 213
RSK3            MLT-GSL-PFQG---------KDRK----ETMTLI--------------- 213
RSK2            MLT-GTL-PFQG---------KDRK----ETMTMI--------------- 213
RSK4            MLT-GTL-PFQG---------KDRN----ETMNMI--------------- 213
1FOTA           MLA-GYT-PFYD---------SNTM----KTYEKI--------------- 208
1CDKA           MAA-GYP-PFFA---------DQPI----QIYEKI--------------- 208
PKACA           MAA-GYP-PFFA---------DQPI----QIYEKI--------------- 208
PKACB           MAA-GYP-PFFA---------DQPI----QIYEKI--------------- 208
PKACG           MAV-GFP-PFYA---------DQPI----QIYEKI--------------- 208
PRKX            MLS-GFP-PFFD---------DNPF----GIYQKI--------------- 208
PRKY            MLS-GFP-PFFD---------DNPF----GIYQKI--------------- 208
PKCA            MLA-GQP-PFDG---------EDED----ELFQSI--------------- 212
PKCB            MLA-GQA-PFEG---------EDED----ELFQSI--------------- 212
PKCG            MLA-GQP-PFDG---------EDEE----ELFQAI--------------- 217
PKCE            MMA-GQP-PFEA---------DNED----DLFESI--------------- 212
PKCH            MLC-GHA-PFEA---------ENED----DLFEAI--------------- 212
PKCD            MLI-GQS-PFHG---------DDED----ELFESI--------------- 212
PKCT            MLI-GQS-PFHG---------QDEE----ELFHSI--------------- 212
PKCI            MMA-GRS-PFDIVGSSDNPDQNTED----YLFQVI--------------- 221
PKCZ            MMA-GRS-PFDII--TDNPDMNTED----YLFQVI--------------- 219
PKN1            MLV-GES-PFPG---------DDEE----EVFDSI--------------- 213
PKN2            MLV-GES-PFPG---------DDEE----EVFDSI--------------- 213
PKN3            MLV-GEC-PFPG---------DTEE----EVFDCI--------------- 213
SGK             MLY-GLP-PFYS---------RNTA----EMYDNI--------------- 212
SGK2            MLH-GLP-PFYS---------QDVS----QMYENI--------------- 212
SGK3            MLY-GLP-PFYC---------RDVA----EMYDNI--------------- 212
PKG1            LLT-GSP-PFSG---------PDPM----KTYNII--------------- 211
PKG2            LLT-GNP-PFSG---------VDQM----MTYNLI--------------- 210
AURB            LLV-GNP-PFESASHNETYRRIVKV------------------------- 212
AURC            LLV-GYP-PFESASHSETYRRILKV------------------------- 212
AURA            FLV-GKP-PFEANTYQETYKRISRV------------------------- 212
AURORA2_AVE     FLV-GKP-PFEANTYQETYKRISRV------------------------- 201
PLK1            LLV-GKP-PFETSCLKETYLRIKKN------------------------- 214
PLK2            MLL-GRP-PFETTNLKETYRCIREA------------------------- 214
PLK3            LLC-GSP-PFETADLKETYRCIKQV------------------------- 214
PLK4            LLI-GRP-PFDTDTVKNTLNKVVLA------------------------- 215
NEK11           MCC-MNH-AFAGSNFLSIVLKIVEG------------------------- 219
YANK1           LLR-GRR-PYHIRSSTSSKEIVHTF------------------------- 216
YANK2           LLR-GWR-PYEIHSVTPIDEILNMF------------------------- 218
YANK3           LLR-GWR-PYDIHSSNAVESLVQLF------------------------- 218
SGK494          LAT-GKF-PVAAERDH--VAMLASV------------------------- 210
DOMAIN2_MSK1    MLS-GQV-PFQSHDRSLT--------CTSAVEIMKKIKKG---------- 219
DOMAIN2_MSK2    MLS-GQV-PFQGASGQGG--------QSQAAEIMCKIREG---------- 215
DOMAIN2_RSK1    MLA-GFT-PFANGP------------DDTPEEILARIGSG---------- 215
DOMAIN2_RSK2    MLT-GYT-PFANGP------------DDTPEEILARIGSG---------- 215
DOMAIN2_RSK3    MLA-GYT-PFANGP------------SDTPEEILTRIGSG---------- 215
DOMAIN2_RSK4    MLA-GYT-PFANGP------------NDTPEEILLRIGNG---------- 215
DRAK1           MLT-GIS-PFLGND---------------KQETFLNISQM---------- 218
DRAK2           LLT-HTS-PFVGED---------------NQETYLNISQV---------- 218
1JKSA           LLS-GAS-PFLGDT---------------KQETLANVSAV---------- 220
DAPK1           LLS-GAS-PFLGDT---------------KQETLANVSAV---------- 220
DAPK3           LLS-GAS-PFLGET---------------KQETLTNISAV---------- 220
DAPK2           LLS-GAS-PFLGDT---------------KQETLANITAV---------- 220
SGK085          LLS-GLS-PFLGDN---------------DAETLNNILAC---------- 213
CAMLCK          LLS-GLS-PFLGET---------------DAETMNFIVNC---------- 213
SKMLCK          LLS-GLS-PFLGDD---------------DTETLNNVLSG---------- 213
SMMLCK          LVS-GLS-PFMGDN---------------DNETLANVTSA---------- 213
1KOBA           LLS-GLS-PFAGED---------------DLETLQNVKRC---------- 213
1TKIA           LLS-GIN-PFLAET---------------NQQIIENIMNA---------- 212
TTN             LLS-GIN-PFLAET---------------NQQIIENIMNA---------- 212
PKD1            SLS-GTF-PFNED-----------------EDIHDQIQNA---------- 214
PKD3            SLS-GTF-PFNED-----------------EDINDQIQNA---------- 214
PKD2            SLS-GTF-PFNED-----------------EDINDQIQNA---------- 214
PSKH1           LLS-GTM-PFEDDN---------------RTRLYRQILRG---------- 215
PSKH2           LLS-GFL-PFDDES---------------QTRLYRKILKG---------- 215
CAMK1A          LLC-GYP-PFYDEN---------------DAKLFEQILKA---------- 214
CAMK1D          LLC-GYP-PFYDEN---------------DSKLFEQILKA---------- 214
CAMK1B          LLC-GYP-PFYDES---------------DPELFSQILRA---------- 213
CAMK1G          LLC-GYP-PFYEET---------------ESKLFEKIKEG---------- 212
CAMK4           LLC-GFE-PFYDERG--------------DQFMFRRILNC---------- 212
DCAMKL1         LLC-GFP-PFRGSGD-------------DQEVLFDQILMG---------- 215
DCAMKL2         LLC-GFP-PFRSENN-------------LQEDLFDQILAG---------- 215
DCAMKL3         LLC-GFP-PFRSPE-------------RDQDELFNIIQLG---------- 215
CHK2            CLS-GYP-PFSEHRT--------------QVSLKDQITSG---------- 224
MAPKAPK2        LLC-GYP-PFYSNHGLA-----------ISPGMKTRIRMG---------- 219
MAPKAPK3        LLC-GFP-PFYSNTGQA-----------ISPGMKRRIRLG---------- 218
MAPKAPK5        MLC-GYP-PFYSKHHSRT----------IPKDMRRKIMTG---------- 240
MNK1            MLS-GYP-PFVGHCGADCGWDRGEVCRVCQNKLFESIQEG---------- 243
MNK2            LLS-GYP-PFVGRCGSDCGWDRGEACPACQNMLFESIQEG---------- 242
VACAMKL         ----GNP-PFYEEVEEDDY-------ENHDKNLFRKILAG---------- 192
GCK             LGE-LQP-PLFHL-H--PMRALMLMSKSSFQPPKL--------------- 221
KHS1            LGE-LQP-PMFDL-H--PMRALFLMSKSNFQPPKL--------------- 221
KHS2            LAE-LQP-PMFDL-H--PMRALFLMTKSNFQPPKL--------------- 221
HPK1            LAE-LQP-PLFDV-H--PLRVLFLMTKSGYQPPRL--------------- 221
MST1            MAE-GKP-PYADI-H--PMRAIFMIPTNP--PPTF--------------- 215
MST2            MAE-GKP-PYADI-H--PMRAIFMIPTNP--PPTF--------------- 215
MST3            LAR-GEP-PHSEL-H--PMKVLFLIPKNN--PPTL--------------- 216
YSK1            LAK-GEP-PNSDL-H--PMRVLFLIPKNS--PPTL--------------- 216
MST4            LAK-GEP-PNSDM-H--PMRVLFLIPKNN--PPTL--------------- 216
LOK             MAQ-IEP-PHHEL-N--PMRVLLKIAKSD--PPTL--------------- 222
SLK             MAE-IEP-PHHEL-N--PMRVLLKIAKSE--PPTL--------------- 222
MAP3K4          MVT-GKR-PWHEYEH--NFQIMYKVGMGH--KPPI--------------- 224
MAP3K2          MLT-EKP-PWAEF-E--AMAAIFKIATQP-TNPKL--------------- 227
MAP3K3          MLT-EKP-PWAEY-E--AMAAIFKIATQP-TNPQL--------------- 227
MAP3K8          MAT-GKP-PLASM-D--RMAAMFYIGAHRGLMPPL--------------- 229
MAP3K5          MAT-GKP-PFYELGE--PQAAMFKVGMFK-VHPEI--------------- 229
MAP3K7          MAT-SKP-PFHELGE--PQAAMFKVGMFK-IHPEI--------------- 220
MAP3K6          MAT-GRP-PFHELGS--PQAAMFQVGMYK-VHPPM--------------- 219
PAK1            MIE-GEP-PYLNE-N--PLRALYLIATNG--TPEL--------------- 215
PAK3            MVE-GEP-PYLNE-N--PLRALYLIATNG--TPEL--------------- 215
PAK2            MVE-GEP-PYLNE-N--PLRALYLIATNG--TPEL--------------- 216
PAK4            MVD-GEP-PYFNE-P--PLKAMKMIRDNL--PPRL--------------- 215
PAK5            MID-GEP-PYFNE-P--PLQAMRRIRDSL--PPRV--------------- 215
PAK6            MVD-GEP-PYFSD-S--PVQAMKRLRDSP--PPKL--------------- 215
OSR1            LAT-GAA-PYHKY-P--PMKVLMLTLQND--PPSL--------------- 231
STLK3           LAT-GAA-PYHKY-P--PMKVLMLTLQND--PPTL--------------- 231
TAO1            LAE-RKP-PLFNM-N--AMSALYHIAQNE--SPTL--------------- 218
TAO3            LAE-RKP-PLFNM-N--AMSALYHIAQND--SPTL--------------- 218
TAO2            LAE-RKP-PLFNM-N--AMSALYHIAQNE--SPVL--------------- 218
MYO3A           LGD-GDP-PLADL-H--PMRALFKIPRNP--PPKL--------------- 230
MYO3B           LGD-GDP-PLFDM-H--PVKTLFKIPRNP--PPTL--------------- 230
ZC1/HGK         MAE-GAP-PLCDM-H--PMRALFLIPRNP--PPRL--------------- 229
ZC3/MINK        MAE-GAP-PLCDM-H--PMRALFLIPRNP--PPRL--------------- 229
ZC2/TNIK        MAE-GAP-PLCDM-H--PMRALFLIPRNP--APRL--------------- 229
ZC4/NRK         MAE-GAP-PLCNL-Q--PLEALFVILRES--APTV--------------- 253
MAP3K1          MAC-AKP-PWNAEKHSNHLALIFKIASAT-TAPSI--------------- 231
GAK             LCF-RQH-PFE--DGAKL----RIV------------------------- 233
SGK495          MLY-GQF-PFY--DSIPQELFRKIK------------------------- 130
TRB1            LLV-GRY-PFH--DSDPSALFSKIR------------------------- 199
TRB2            MLV-GRY-PFH--DIEPSSLFSKIR------------------------- 204
TRB3            MLA-GHY-PFQ--DSEPVLLFGKIR------------------------- 202
SSTK            MVT-GCM-PFD--DSDIAGLPRRQK------------------------- 214
TSSK3           MLC-ASL-PFD--DTDIPKMLWQQQ------------------------- 214
TSSK1           MVC-GSM-PYD--DSNIKKMLRIQK------------------------- 218
TSSK2           MVC-GSM-PYD--DSDIRKMLRIQK------------------------- 218
TSSK4           LVV-AHL-PFD--DTNLKKLLRETQ------------------------- 228
HUNK            MLT-GTL-PFTVEPFSLRALYQKMV------------------------- 218
SNRK            LVC-GQP-PFQ--EANDSETLTMIM------------------------- 213
NIM1            MVT-GTM-PFR--AETVAKLKKSIL------------------------- 211
MELK            LMC-GFL-PFD--DDNVMALYKKIM------------------------- 212
BRSK1           LLV-GAL-PFD--DDNLRQLLEKVK------------------------- 211
BRSK2           LLV-GAL-PFD--DDNLRQLLEKVK------------------------- 211
MARK1           LVS-GSL-PFD--GQNLKELRERVL------------------------- 211
MARK2           LVS-GSL-PFD--GQNLKELRERVL------------------------- 211
MARK3           LVS-GSL-PFD--GQNLKELRERVL------------------------- 211
MARK4           LVS-GSL-PFD--GHNLKELRERVL------------------------- 211
QIK             LVC-GAL-PFD--GPTLPILRQRVL------------------------- 211
SIK             LVC-GSL-PFD--GPNLPTLRQRVL------------------------- 211
QSK             LVC-GAL-PFD--GSTLQNLRARVL------------------------- 211
AMPKA1          LLC-GTL-PFD--DDHVPTLFKKIC------------------------- 212
AMPKA2          LLC-GTL-PFD--DEHVPTLFKKIR------------------------- 212
NUAK1           LVY-GTM-PFD--GFDHKNLIRQIS------------------------- 212
NUAK2           LVH-GTM-PFD--GHDHKILVKQIS------------------------- 211
BIKE            LCF-FTL-PFG--ESQVA-----IC------------------------- 224
AAK1            LCY-FTL-PFG--ESQVA-----IC------------------------- 225
LIMK1           IIG-RVN-ADPDY--LPRTMDFGLN------------------------- 224
LIMK2           IIG-QVY-ADPDC--LPRTLDFGLN------------------------- 229
TESK1           LIA-RVP-ADPDY--LPRTEDFGLD------------------------- 214
TESK2           IIA-RIQ-ADPDY--LPRTENFGLD------------------------- 192
WNK1            MAT-SEY-PYSEC-QNAAQIYRRVT------------------------- 216
WNK3            MAT-SEY-PYSEC-QNAAQIYRKVT------------------------- 216
WNK2            MAT-SEY-PYSEC-QNAAQIYRKVT------------------------- 216
WNK4            MAT-SEY-PYSEC-QNAAQIYRKVT------------------------- 216
NEK10           MAT-LSP-PFYST--NMLSLATKIV------------------------- 224
NEK6            MAA-LQS-PFYGDKMNLFSLCQKIE------------------------- 218
NEK7            MAA-LQS-PFYGDKMNLYSLCKKIE------------------------- 218
NEK2            LCA-LMP-PFTAF--SQKELAGKIR------------------------- 222
NEK1            LCT-LKH-AFEAG--SMKNLVLKII------------------------- 213
NEK5            LCT-LKH-PFEGN--NLQQLVLKIC------------------------- 214
NEK3            LCT-LKH-PFQAN--SWKNLILKVC------------------------- 212
NEK4            MAT-LKH-AFNAK--DMNSLVYRII------------------------- 214
NEK8            LAS-LKR-AFEAA--NLPALVLKIM------------------------- 206
NEK9            LLT-LKR-TFDAT--NPLNLCVKIV------------------------- 213
NRBP1           MAV-LEI-QGNGES--SY-----VP------------------------- 220
NRBP2           MAV-LEI-QTNGDT--------RVT------------------------- 232
CLIK1           MIE-RIT-FIDSETKKELLGTYIKQGTEIVPVGEAL-------------- 279
CLIK1L          MLE-RIT-FIDTETKKELLGSYVKQGTEIVPVGEAL-------------- 276
STK33           LL----------RGEPPFLASSEAKLFELIRKGELH-------------- 226
DOMAIN2_GCN2    LSQ-GQE-CGEY-------------------------------------- 221
SCYL1           VFN-GP-LPRAA-------------------------------------- 196
SCYL3           LLT-ILNEQV---------------------------------------- 185
DOMAIN2_JAK1    ICY-NGEIPLKDKTLIE--------------------------------- 219
DOMAIN2_TYK2    ICF-DGEAPLQSRSPSE--------------------------------- 234
DOMAIN2_JAK2    ICS-GGDKPLSALDSQR--------------------------------- 217
DOMAIN2_JAK3    VFS-GVTMPISALDPAK--------------------------------- 213
ILK             LVT-RE-VPFADLSNMEIG------------------------------- 209
LRRK1           LLS-GQ-RPALGHHQLQIA------------------------------- 232
PBK             MMT-LS-IPHINLSNDDDDEDKT--------------------------- 229
WEE1            AAG-AEPLPRNGD------------------------------------- 223
WEE1B           AAG-AESLPTNGA------------------------------------- 227
SGK071          MTS-CSFMDGTEAM------------------------------------ 212
PIK3R4          LFT-EG-VPLFDLSQLLAY------------------------------- 242
MSSK1           LAT-GDYL-FEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFF 391
SRPK1           LAT-GDYL-FEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFF 512
SRPK2           LAT-GDYL-FEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFF 544
RSKL1           LLT-GKTL-VECHPAGINTHT----------------------------- 191
RSKL2           LLT-GMAL-SQSHPSGIQAHT----------------------------- 343
SGK396          LSV-QN-QEFEINKX----------------------------------- 201
VRK1            WLT-GHL-PWEDNLKDPKYVRD---------------------------- 237
VRK2            WLC-GKL-PWEQNLKDPVAVQ----------------------------- 233
VRK3            WLY-GFL-PWTNCLPNTEDIM----------------------------- 181
BUB1            MLF-GTYMKVKNEGG----------------------------------- 225
BUBR1           LLF-KEHLQVFWD------------------------------------- 222
SGK196          HIE-GSDMV----------------------------------------- 222
SGK493          WCE-GMNEKRNLYN------------------------------------ 202
                                                                  

DYRK1A          --AH-ILDQAPKARKFFEKLPDGTWN----LKKTKDGKRE---YKPPGTR 263
DYRK1B          --AA-MLDQAPKARKYFERLPGGGWT----LRRTKELRKDYQGPGTRR-- 264
DYRK2           --QK-LLDASKRAKNFVSSKGYPR---YCTVTTLSDGSVVLNGGRSRRG- 264
DYRK3           --PK-LLEQSKRAKYFINSKGIPR---YCSVTTQADGRVVLVGGRSRRG- 264
DYRK4           --AG-FIQTASRRQTFFDSKGFPKNI------------------TNNRG- 249
HIPK1           --EY-LLSAGTKTTRFFNRDPNLGYPL-WRLKTPEEHEL-ETGIKSKEAR 268
HIPK2           --EY-LLSAGTKTTRFFNRDTDSPYPL-WRLKTPDDHEA-ETGIKSKEAR 268
HIPK3           --EQ-LLNVGTKSTRFFCKETDMSHSG-WRLKTLEEHEA-ETGMKSKEAR 268
HIPK4           --PH-LLHAACKAH------------------------------------ 236
PRP4            --NK-MIRKGVFKDQHFDQNLNFM---YIEVDKVTEREK-VTVMSTINPT 266
MOK             --QK-ILTKFKQSRAMNFDFP----------------------------- 237
1A6O            --LNVYLNKYRIELDPQLE--------------------ALVGRHSRKPW 243
1LPUA           --LNVYLNKYRIELDPQLE--------------------ALVGRHSRKPW 243
CK2A1           --LYDYIDKYNIELDPRFN--------------------DILGRHSRKRW 243
CK2A1-RS        --LYGYIDKYNIELDPRFN--------------------DILGRHSRKRW 243
CK2A2           --LYGYLKKYHIDLDPHFN--------------------DILGQHSRKRW 243
HSER            -GMKPFR------------------------------------------- 217
SLOB            -------------------------------------------------- 212
CDC7            VPAQDLRKLCERLRGMDSSTPK--------LTSDIQGHASHQPAISEKTD 437
1CSN            --LREL-------------------------------------------- 234
CK1G1           --IEAL-------------------------------------------- 235
CK1G3           --IEVL-------------------------------------------- 234
CK1G2           --IEVL-------------------------------------------- 234
CK1A            --VEVL-------------------------------------------- 232
CK1A2           --VEVL-------------------------------------------- 232
1CKJA           --IEVL-------------------------------------------- 232
CK1D            --IEVL-------------------------------------------- 232
CK1E            --IEVL-------------------------------------------- 232
TTBK1           --HRML-------------------------------------------- 227
TTBK2           --HRLM-------------------------------------------- 227
TLK1            -TEVQFP------------------------------------------- 243
TLK2            -TEVQFP------------------------------------------- 244
GPRK4           -DTEEYS------------------------------------------- 224
GPRK6           -VPEEYS------------------------------------------- 224
GPRK5           -TEEVYS------------------------------------------- 224
RHOK            -EPVKYP------------------------------------------- 227
GPRK7           -DEVKFQ------------------------------------------- 225
BARK1           -MAVELP------------------------------------------- 224
BARK2           -VNVELP------------------------------------------- 224
TTK             NHEIEFP------------------------------------------- 233
RIPK1           -------------------------------------------------- 233
HASPIN          -------------------------------------------------- 288
GCN2            -------------------------------------------------- 372
HRI             -------------------------------------------------- 378
KIS             -------------------------------------------------- 235
PDK1            -------------------------------------------------- 219
PKR             -------------------------------------------------- 236
PEK             -------------------------------------------------- 446
PRPK            -------------------------------------------------- 194
DOMAIN2_OBSCN   -------------------------------------------------- 213
DOMAIN2_SPEG    -------------------------------------------------- 213
LMR1            -------------------------------------------------- 232
LMR2            -------------------------------------------------- 232
LMR3            -------------------------------------------------- 237
SGK307          DV------------------------------------------------ 139
STLK5           VANSGLSDS----------------------------------------- 258
STLK6           GVDSGIGES----------------------------------------- 258
STLK6-RS        GVDSGIGES----------------------------------------- 258
OBSCN           -------------------------------------------------- 213
SPEG            -------------------------------------------------- 214
TRAD            -------------------------------------------------- 214
TRIO            -------------------------------------------------- 214
SGK223          -------------------------------------------------- 265
SGK269          -------------------------------------------------- 237
ALK1            -------------------------------------------------- 232
ALK2            -------------------------------------------------- 232
IRAK4           -------------------------------------------------- 221
BMPR2           -------------------------------------------------- 242
TGFBR2          -------------------------------------------------- 239
ACTR2           -------------------------------------------------- 232
ACTR2B          -------------------------------------------------- 233
1B6CB           -------------------------------------------------- 232
TGFBR1          -------------------------------------------------- 232
ALK4            -------------------------------------------------- 232
ALK7            -------------------------------------------------- 232
BMPR1A          -------------------------------------------------- 232
BMPR1B          -------------------------------------------------- 232
IRAK1           -------------------------------------------------- 243
IRAK2           -------------------------------------------------- 238
IRAK3           -------------------------------------------------- 248
MISR2           RPDSSPPPF----------------------------------------- 234
MYT1            -------------------------------------------------- 212
SBK             -------------------------------------------------- 207
SGK110          -------------------------------------------------- 206
SGK069          -------------------------------------------------- 209
SGK496          -------------------------------------------------- 203
NIK             -------------------------------------------------- 232
SGK424          -------------------------------------------------- 0
SURTK106        READRPSPR----------------------------------------- 261
IKKE            -------------------------------------------------- 250
TBK1            -------------------------------------------------- 250
MOS             -------------------------------------------------- 246
LKB1            -------------------------------------------------- 224
CAMKK1          -------------------------------------------------- 251
CAMKK2          -------------------------------------------------- 243
PASK            -------------------------------------------------- 216
PIM1            -------------------------------------------------- 216
PIM3            -------------------------------------------------- 217
PIM2            -------------------------------------------------- 218
COT             -------------------------------------------------- 218
SCYL2           -------------------------------------------------- 261
FUSED           -------------------------------------------------- 210
ULK1            -------------------------------------------------- 219
ULK2            -------------------------------------------------- 219
ULK3            -------------------------------------------------- 213
ULK4            -------------------------------------------------- 214
IRE1            -------------------------------------------------- 218
IRE2            -------------------------------------------------- 218
RNASEL          -------------------------------------------------- 184
MPSK1           -------------------------------------------------- 229
PINK1           -------------------------------------------------- 311
ALK             -------------------------------------------------- 229
LTK             -------------------------------------------------- 229
ROS             -------------------------------------------------- 232
IGF1R           -------------------------------------------------- 229
1IR3A           -------------------------------------------------- 229
INSR            -------------------------------------------------- 229
IRR             -------------------------------------------------- 229
1M14A           -------------------------------------------------- 218
EGFR            -------------------------------------------------- 218
HER2/ERBB2      -------------------------------------------------- 218
HER4/ERBB4      -------------------------------------------------- 218
HER3/ERBB3      -------------------------------------------------- 218
ITK             -------------------------------------------------- 211
TEC             -------------------------------------------------- 211
TXK             -------------------------------------------------- 211
BMX             -------------------------------------------------- 211
1K2PA           -------------------------------------------------- 211
BTK             -------------------------------------------------- 211
CCK4            -------------------------------------------------- 226
ROR1            -------------------------------------------------- 235
ROR2            -------------------------------------------------- 235
MUSK            -------------------------------------------------- 243
TRKA            -------------------------------------------------- 233
TRKB            -------------------------------------------------- 231
TRKC            -------------------------------------------------- 234
DDR1            -------------------------------------------------- 254
DDR2            -------------------------------------------------- 245
RYK             -------------------------------------------------- 228
JAK1            -------------------------------------------------- 229
JAK2            -------------------------------------------------- 230
JAK3            -------------------------------------------------- 229
ACK             -------------------------------------------------- 215
TYK2            -------------------------------------------------- 228
TNK1            -------------------------------------------------- 217
EPHA1           -------------------------------------------------- 215
EPHA10          -------------------------------------------------- 214
FAK             -------------------------------------------------- 213
EPHB6           -------------------------------------------------- 204
EPHA2           -------------------------------------------------- 217
EPHA8           -------------------------------------------------- 216
EPHA6           -------------------------------------------------- 258
EPHB1           -------------------------------------------------- 218
EPHB2           -------------------------------------------------- 218
EPHB3           -------------------------------------------------- 218
EPHB4           -------------------------------------------------- 218
EPHA7           -------------------------------------------------- 216
EPHA4           -------------------------------------------------- 216
EPHA3           -------------------------------------------------- 216
EPHA5           -------------------------------------------------- 216
PYK2            -------------------------------------------------- 213
CSK             -------------------------------------------------- 204
CTK             -------------------------------------------------- 202
1IEPA           -------------------------------------------------- 210
ABL             -------------------------------------------------- 210
ARG             -------------------------------------------------- 210
BRK             -------------------------------------------------- 209
SRM             -------------------------------------------------- 209
FRK             -------------------------------------------------- 212
FGR             -------------------------------------------------- 208
FYN             -------------------------------------------------- 208
SRC             -------------------------------------------------- 208
YES             -------------------------------------------------- 208
HCK             -------------------------------------------------- 208
LYN             -------------------------------------------------- 209
3LCK            -------------------------------------------------- 208
LCK             -------------------------------------------------- 208
BLK             -------------------------------------------------- 207
FER             -------------------------------------------------- 210
FES             -------------------------------------------------- 212
SYK             -------------------------------------------------- 214
ZAP70           -------------------------------------------------- 214
FGFR1           -------------------------------------------------- 235
FGFR2           -------------------------------------------------- 235
FGFR3           -------------------------------------------------- 235
FGFR4           -------------------------------------------------- 235
RET             -------------------------------------------------- 240
TIE1            -------------------------------------------------- 227
1FVRA           -------------------------------------------------- 227
TIE2            -------------------------------------------------- 227
FLT1            -------------------------------------------------- 286
KDR             -------------------------------------------------- 285
KDR_AVE         -------------------------------------------------- 225
FLT4            -------------------------------------------------- 283
FMS             -------------------------------------------------- 287
FLT3            -------------------------------------------------- 292
KIT             -------------------------------------------------- 294
PDGFRA          -------------------------------------------------- 316
PDGFRB          -------------------------------------------------- 317
MER             -------------------------------------------------- 226
AXL             -------------------------------------------------- 226
TYRO3           -------------------------------------------------- 227
MET             -------------------------------------------------- 218
RON             -------------------------------------------------- 218
HH498           -------------------------------------------------- 213
LZK             -------------------------------------------------- 196
DLK             -------------------------------------------------- 196
MLK1            -------------------------------------------------- 216
MLK3            -------------------------------------------------- 216
MLK2            -------------------------------------------------- 216
MLK4            -------------------------------------------------- 231
ZAK             -------------------------------------------------- 201
TAK1            -------------------------------------------------- 206
KSR1            -------------------------------------------------- 219
KSR2            -------------------------------------------------- 219
ARAF            -------------------------------------------------- 211
RAF1            -------------------------------------------------- 211
BRAF            -------------------------------------------------- 211
LRRK2           -------------------------------------------------- 207
ANKRD3          -------------------------------------------------- 213
SGK288          -------------------------------------------------- 212
RIPK2           -------------------------------------------------- 223
RIPK3           -------------------------------------------------- 211
MLKL            -------------------------------------------------- 215
ANPA            -------------------------------------------------- 219
ANPB            -------------------------------------------------- 220
CYGD            -------------------------------------------------- 226
CYGF            -------------------------------------------------- 231
TBCK            -------------------------------------------------- 212
ERK1            -------------------------------------------------- 234
3ERK            -------------------------------------------------- 234
ERK2            -------------------------------------------------- 234
ERK5            -------------------------------------------------- 238
1JNK            -------------------------------------------------- 224
1PMNA           -------------------------------------------------- 229
JNK3            -------------------------------------------------- 229
JNK1            -------------------------------------------------- 229
JNK2            -------------------------------------------------- 229
1P38            -------------------------------------------------- 230
P38A            -------------------------------------------------- 230
P38B            -------------------------------------------------- 238
P38D            -------------------------------------------------- 229
P38G            -------------------------------------------------- 230
NLK             -------------------------------------------------- 234
ERK7            -------------------------------------------------- 255
ERK3            -------------------------------------------------- 243
ERK4            -------------------------------------------------- 240
ICK             -------------------------------------------------- 227
MAK             -------------------------------------------------- 227
PCTAIRE1        -------------------------------------------------- 228
PCTAIRE2        -------------------------------------------------- 228
PCTAIRE3        -------------------------------------------------- 228
PFTAIRE1        -------------------------------------------------- 229
PFTAIRE2        -------------------------------------------------- 229
CDC2            -------------------------------------------------- 231
1HCL            -------------------------------------------------- 226
CDK2            -------------------------------------------------- 230
CDK3            -------------------------------------------------- 230
CDK5            -------------------------------------------------- 230
CDK7            -------------------------------------------------- 232
CDK4            -------------------------------------------------- 239
1BLXA           -------------------------------------------------- 237
CDK6            -------------------------------------------------- 237
PITSLRE         -------------------------------------------------- 231
CDK10           -------------------------------------------------- 231
CDK9            -------------------------------------------------- 241
CHED            -------------------------------------------------- 240
CRK7            -------------------------------------------------- 240
CCRK            -------------------------------------------------- 231
CDK11           -------------------------------------------------- 254
CDK8            -------------------------------------------------- 254
IKKA            GEVRFSSHL----------------------------------------- 244
IKKB            GTVKFSSSL----------------------------------------- 245
1PHK            GNYQFGS------------------------------------------- 232
PHKG1           GNYQFGS------------------------------------------- 232
PHKG2           GQYQFSS------------------------------------------- 231
CAMK2A          GAYDFPS------------------------------------------- 222
CAMK2B          GAYDFPS------------------------------------------- 222
CAMK2G          GAYDFPS------------------------------------------- 222
CAMK2D          GAYDFPS------------------------------------------- 222
CASK            GKYKMNP------------------------------------------- 228
1IA8A           EKKTYLN------------------------------------------- 218
CHK1            EKKTYLN------------------------------------------- 221
CLK1            KYFHHDR------------------------------------------- 256
CLK4            KYFHHNQ------------------------------------------- 255
CLK2            KYFYRGR------------------------------------------- 256
CLK3            KYFYKGG------------------------------------------- 256
MAP2K5          -------------------------------------------------- 192
MAP2K3          -------------------------------------------------- 209
MAP2K6          -------------------------------------------------- 209
MAP2K4          -------------------------------------------------- 210
MAP2K7          -------------------------------------------------- 207
MAP2K1          YGMDSRPPM----------------------------------------- 241
MAP2K2          HGMDSRPAM----------------------------------------- 245
CDKL5           -------------------------------------------------- 228
CDKL1           -------------------------------------------------- 228
CDKL4           -------------------------------------------------- 227
CDKL2           -------------------------------------------------- 228
CDKL3           -------------------------------------------------- 227
1I09B           -------------------------------------------------- 229
GSK3B           -------------------------------------------------- 229
1J1BA           -------------------------------------------------- 229
GSK3A           -------------------------------------------------- 229
LATS1           -------------------------------------------------- 267
LATS2           -------------------------------------------------- 267
NDR1            -------------------------------------------------- 255
NDR2            -------------------------------------------------- 255
MAST1           -------------------------------------------------- 233
MAST4           -------------------------------------------------- 233
MAST2           -------------------------------------------------- 233
MAST3           -------------------------------------------------- 233
MRCKA           -------------------------------------------------- 227
MRCKB           -------------------------------------------------- 227
DMPK2           -------------------------------------------------- 227
DMPK1           -------------------------------------------------- 229
ROCK1           -------------------------------------------------- 224
ROCK2           -------------------------------------------------- 224
CRIK            -------------------------------------------------- 228
MASTL           -------------------------------------------------- 227
1O6LA           -------------------------------------------------- 211
AKT2            -------------------------------------------------- 211
AKT1            -------------------------------------------------- 212
AKT3            -------------------------------------------------- 211
MSK1            -------------------------------------------------- 223
MSK2            -------------------------------------------------- 222
P70S6K          -------------------------------------------------- 215
P70S6KB         -------------------------------------------------- 215
RSK1            -------------------------------------------------- 213
RSK3            -------------------------------------------------- 213
RSK2            -------------------------------------------------- 213
RSK4            -------------------------------------------------- 213
1FOTA           -------------------------------------------------- 208
1CDKA           -------------------------------------------------- 208
PKACA           -------------------------------------------------- 208
PKACB           -------------------------------------------------- 208
PKACG           -------------------------------------------------- 208
PRKX            -------------------------------------------------- 208
PRKY            -------------------------------------------------- 208
PKCA            -------------------------------------------------- 212
PKCB            -------------------------------------------------- 212
PKCG            -------------------------------------------------- 217
PKCE            -------------------------------------------------- 212
PKCH            -------------------------------------------------- 212
PKCD            -------------------------------------------------- 212
PKCT            -------------------------------------------------- 212
PKCI            -------------------------------------------------- 221
PKCZ            -------------------------------------------------- 219
PKN1            -------------------------------------------------- 213
PKN2            -------------------------------------------------- 213
PKN3            -------------------------------------------------- 213
SGK             -------------------------------------------------- 212
SGK2            -------------------------------------------------- 212
SGK3            -------------------------------------------------- 212
PKG1            -------------------------------------------------- 211
PKG2            -------------------------------------------------- 210
AURB            -------------------------------------------------- 212
AURC            -------------------------------------------------- 212
AURA            -------------------------------------------------- 212
AURORA2_AVE     -------------------------------------------------- 201
PLK1            -------------------------------------------------- 214
PLK2            -------------------------------------------------- 214
PLK3            -------------------------------------------------- 214
PLK4            -------------------------------------------------- 215
NEK11           -------------------------------------------------- 219
YANK1           -------------------------------------------------- 216
YANK2           -------------------------------------------------- 218
YANK3           -------------------------------------------------- 218
SGK494          -------------------------------------------------- 210
DOMAIN2_MSK1    -------------------------------------------------- 219
DOMAIN2_MSK2    -------------------------------------------------- 215
DOMAIN2_RSK1    -------------------------------------------------- 215
DOMAIN2_RSK2    -------------------------------------------------- 215
DOMAIN2_RSK3    -------------------------------------------------- 215
DOMAIN2_RSK4    -------------------------------------------------- 215
DRAK1           -------------------------------------------------- 218
DRAK2           -------------------------------------------------- 218
1JKSA           -------------------------------------------------- 220
DAPK1           -------------------------------------------------- 220
DAPK3           -------------------------------------------------- 220
DAPK2           -------------------------------------------------- 220
SGK085          -------------------------------------------------- 213
CAMLCK          -------------------------------------------------- 213
SKMLCK          -------------------------------------------------- 213
SMMLCK          -------------------------------------------------- 213
1KOBA           -------------------------------------------------- 213
1TKIA           -------------------------------------------------- 212
TTN             -------------------------------------------------- 212
PKD1            -------------------------------------------------- 214
PKD3            -------------------------------------------------- 214
PKD2            -------------------------------------------------- 214
PSKH1           -------------------------------------------------- 215
PSKH2           -------------------------------------------------- 215
CAMK1A          -------------------------------------------------- 214
CAMK1D          -------------------------------------------------- 214
CAMK1B          -------------------------------------------------- 213
CAMK1G          -------------------------------------------------- 212
CAMK4           -------------------------------------------------- 212
DCAMKL1         -------------------------------------------------- 215
DCAMKL2         -------------------------------------------------- 215
DCAMKL3         -------------------------------------------------- 215
CHK2            -------------------------------------------------- 224
MAPKAPK2        -------------------------------------------------- 219
MAPKAPK3        -------------------------------------------------- 218
MAPKAPK5        -------------------------------------------------- 240
MNK1            -------------------------------------------------- 243
MNK2            -------------------------------------------------- 242
VACAMKL         -------------------------------------------------- 192
GCK             -------------------------------------------------- 221
KHS1            -------------------------------------------------- 221
KHS2            -------------------------------------------------- 221
HPK1            -------------------------------------------------- 221
MST1            -------------------------------------------------- 215
MST2            -------------------------------------------------- 215
MST3            -------------------------------------------------- 216
YSK1            -------------------------------------------------- 216
MST4            -------------------------------------------------- 216
LOK             -------------------------------------------------- 222
SLK             -------------------------------------------------- 222
MAP3K4          -------------------------------------------------- 224
MAP3K2          -------------------------------------------------- 227
MAP3K3          -------------------------------------------------- 227
MAP3K8          -------------------------------------------------- 229
MAP3K5          -------------------------------------------------- 229
MAP3K7          -------------------------------------------------- 220
MAP3K6          -------------------------------------------------- 219
PAK1            -------------------------------------------------- 215
PAK3            -------------------------------------------------- 215
PAK2            -------------------------------------------------- 216
PAK4            -------------------------------------------------- 215
PAK5            -------------------------------------------------- 215
PAK6            -------------------------------------------------- 215
OSR1            -------------------------------------------------- 231
STLK3           -------------------------------------------------- 231
TAO1            -------------------------------------------------- 218
TAO3            -------------------------------------------------- 218
TAO2            -------------------------------------------------- 218
MYO3A           -------------------------------------------------- 230
MYO3B           -------------------------------------------------- 230
ZC1/HGK         -------------------------------------------------- 229
ZC3/MINK        -------------------------------------------------- 229
ZC2/TNIK        -------------------------------------------------- 229
ZC4/NRK         -------------------------------------------------- 253
MAP3K1          -------------------------------------------------- 231
GAK             -------------------------------------------------- 233
SGK495          -------------------------------------------------- 130
TRB1            -------------------------------------------------- 199
TRB2            -------------------------------------------------- 204
TRB3            -------------------------------------------------- 202
SSTK            -------------------------------------------------- 214
TSSK3           -------------------------------------------------- 214
TSSK1           -------------------------------------------------- 218
TSSK2           -------------------------------------------------- 218
TSSK4           -------------------------------------------------- 228
HUNK            -------------------------------------------------- 218
SNRK            -------------------------------------------------- 213
NIM1            -------------------------------------------------- 211
MELK            -------------------------------------------------- 212
BRSK1           -------------------------------------------------- 211
BRSK2           -------------------------------------------------- 211
MARK1           -------------------------------------------------- 211
MARK2           -------------------------------------------------- 211
MARK3           -------------------------------------------------- 211
MARK4           -------------------------------------------------- 211
QIK             -------------------------------------------------- 211
SIK             -------------------------------------------------- 211
QSK             -------------------------------------------------- 211
AMPKA1          -------------------------------------------------- 212
AMPKA2          -------------------------------------------------- 212
NUAK1           -------------------------------------------------- 212
NUAK2           -------------------------------------------------- 211
BIKE            -------------------------------------------------- 224
AAK1            -------------------------------------------------- 225
LIMK1           -------------------------------------------------- 224
LIMK2           -------------------------------------------------- 229
TESK1           -------------------------------------------------- 214
TESK2           -------------------------------------------------- 192
WNK1            -------------------------------------------------- 216
WNK3            -------------------------------------------------- 216
WNK2            -------------------------------------------------- 216
WNK4            -------------------------------------------------- 216
NEK10           -------------------------------------------------- 224
NEK6            -------------------------------------------------- 218
NEK7            -------------------------------------------------- 218
NEK2            -------------------------------------------------- 222
NEK1            -------------------------------------------------- 213
NEK5            -------------------------------------------------- 214
NEK3            -------------------------------------------------- 212
NEK4            -------------------------------------------------- 214
NEK8            -------------------------------------------------- 206
NEK9            -------------------------------------------------- 213
NRBP1           -------------------------------------------------- 220
NRBP2           -------------------------------------------------- 232
CLIK1           -------------------------------------------------- 279
CLIK1L          -------------------------------------------------- 276
STK33           -------------------------------------------------- 226
DOMAIN2_GCN2    -------------------------------------------------- 221
SCYL1           -------------------------------------------------- 196
SCYL3           -------------------------------------------------- 185
DOMAIN2_JAK1    -------------------------------------------------- 219
DOMAIN2_TYK2    -------------------------------------------------- 234
DOMAIN2_JAK2    -------------------------------------------------- 217
DOMAIN2_JAK3    -------------------------------------------------- 213
ILK             -------------------------------------------------- 209
LRRK1           -------------------------------------------------- 232
PBK             -------------------------------------------------- 229
WEE1            -------------------------------------------------- 223
WEE1B           -------------------------------------------------- 227
SGK071          -------------------------------------------------- 212
PIK3R4          -------------------------------------------------- 242
MSSK1           NRRGEL-------------------------------------------- 397
SRPK1           TKKGDL-------------------------------------------- 518
SRPK2           NRRGEL-------------------------------------------- 550
RSKL1           -------------------------------------------------- 191
RSKL2           -------------------------------------------------- 343
SGK396          -------------------------------------------------- 201
VRK1            -------------------------------------------------- 237
VRK2            -------------------------------------------------- 233
VRK3            -------------------------------------------------- 181
BUB1            -------------------------------------------------- 225
BUBR1           -------------------------------------------------- 222
SGK196          -------------------------------------------------- 222
SGK493          -------------------------------------------------- 202
                                                                  

DYRK1A          K-LHNILG--VETGGPGGRRAGES---------------------GHTVA 289
DYRK1B          --LQEVLG--VQTGGPGGRRAGEP---------------------GHSPA 289
DYRK2           ----------KLRGPPESREWGNA---------------------LKGCD 283
DYRK3           ----------KKRGPPGSKDWGTA---------------------LKGCD 283
DYRK4           ----------KKRYP-DSKDLTMV-----------------------LKT 265
HIPK1           KYIFNCLDDMAQVNMSTDLEGTDM---------------------LAEKA 297
HIPK2           KYIFNCLDDMAQVNMTTDLEGSDM---------------------LVEKA 297
HIPK3           KYIFNSLDDVAHVNTVMDLEGSDL---------------------LAEKA 297
HIPK4           -------------------------------------------------- 236
PRP4            KDLLA------------------------DLIGCQRLPEDQRKK------ 286
MOK             -------------------------------------FKKGSGIPLLTTN 250
1A6O            LKFMNA---------------------------------------DNQHL 254
1LPUA           LKFMNA---------------------------------------DNQHL 254
CK2A1           ERFVHS---------------------------------------ENQHL 254
CK2A1-RS        ERFVHR---------------------------------------ENQHL 254
CK2A2           ENFIHS---------------------------------------ENRHL 254
HSER            ----------------------------------------PDLFLETAEE 227
SLOB            ------------------------------------------------PA 214
CDC7            HKAS------CLVQTPPGQYSGNS-FKKGDSNSCEHCFDEYNTNLEGWNE 480
1CSN            -----------------------------------------------CAG 237
CK1G1           -----------------------------------------------CEN 238
CK1G3           -----------------------------------------------CEN 237
CK1G2           -----------------------------------------------CEN 237
CK1A            -----------------------------------------------CKG 235
CK1A2           -----------------------------------------------CKG 235
1CKJA           -----------------------------------------------CKG 235
CK1D            -----------------------------------------------CKG 235
CK1E            -----------------------------------------------CKG 235
TTBK1           -----------------------------------------------LKH 230
TTBK2           -----------------------------------------------LKH 230
TLK1            ----------------------------------------------VKPV 247
TLK2            ----------------------------------------------PKPV 248
GPRK4           ------------------------------------------------EK 226
GPRK6           ------------------------------------------------ER 226
GPRK5           ------------------------------------------------HK 226
RHOK            ------------------------------------------------DK 229
GPRK7           -----------------------------------------------HDN 228
BARK1           ------------------------------------------------DS 226
BARK2           ------------------------------------------------DT 226
TTK             ------------------------------------------------DI 235
RIPK1           --------------------------------------------DDITEY 239
HASPIN          -------------------------------------------------- 288
GCN2            -----------------------------------FPEDFDDGEHAKQ-- 385
HRI             -----------------------------------LPESLRK-RCPVQ-- 390
KIS             -----------------------------------IDHIFASKAVVNAAI 250
PDK1            -----------------------------------FPEKFFP----KA-- 228
PKR             -----------------------------------ISDIFDK----KE-- 245
PEK             -----------------------------------FPPLFTQ-KYPCE-- 458
PRPK            -----------------------------------TSSK-------KA-- 200
DOMAIN2_OBSCN   ----------------------------------------RLSRC-YAG- 221
DOMAIN2_SPEG    ----------------------------------------D-AFQLYPN- 221
LMR1            ----------------------------------------KLPKPQLQLT 242
LMR2            ----------------------------------------KLPKPQLEQP 242
LMR3            ----------------------------------------KLARPKLKLP 247
SGK307          ----------------------------------------RLPKPYYDIV 149
STLK5           ----------------------------LTTSTPRPSNGDSPSHPYHR-T 279
STLK6           ---------------------------VLVSSGTHTVNSDRLHTPSSK-T 280
STLK6-RS        ---------------------------VLVSSGTHTVNSDRLHTPSSK-T 280
OBSCN           ----------------------------------------SWSSPMAAH- 222
SPEG            ----------------------------------------AFEETTFLS- 223
TRAD            ----------------------------------------SFPHEYFCG- 223
TRIO            ----------------------------------------SFPDDYFKG- 223
SGK223          --------------------------------------EDLPPLPALS-L 276
SGK269          --------------------------------------ADLPRIPFRS-P 248
ALK1            ----------------------SF-EDMKKVVCVDQQTPTIPNRLAADP- 258
ALK2            ----------------------SF-EDMRKVVCVDQQRPNIPNRWFSDP- 258
IRAK4           -------------------------EKTIEDYIDKKMNDADS-------T 239
BMPR2           ----------------------TF-EDMQVLVSREKQRPKFPEAWKENSL 269
TGFBR2          ----------------------CV-ESMKDNVLRDRGRPEIPSFWLNHQ- 265
ACTR2           ----------------------SL-EDMQEVVVHKKKRPVLRDYWQKHA- 258
ACTR2B          ----------------------SL-EELQEVVVHKKMRPTIKDHWLKHP- 259
1B6CB           ----------------------SV-EEMRKVVCEQKLRPNIPNRWQSCE- 258
TGFBR1          ----------------------SV-EEMRKVVCEQKLRPNIPNRWQSCE- 258
ALK4            ----------------------SI-EEMRKVVCDQKLRPNIPNWWQSYE- 258
ALK7            ----------------------SI-EEMRKVVCDQKFRPSIPNQWQSCE- 258
BMPR1A          ----------------------SY-EDMREVVCVKRLRPIVSNRWNSDE- 258
BMPR1B          ----------------------SY-EDMREIVCIKKLRPSFPNRWSSDE- 258
IRAK1           --------TLQAGLAADAWAAPIA-MQIYKKHLDPRPGPCPP-------E 277
IRAK2           -------NVMAKEIC--------------------------------QKY 249
IRAK3           -------NFSAKLFC----------------------------------- 256
MISR2           -------QL---AYEAELGNTPTS-DELWALAVQERRRPYIPSTWRCFAT 273
MYT1            ------------------------------------------PEFTA--G 218
SBK             --------------------DAFF-EEFVRW--QRGRLPGLPSQWRRF-- 232
SGK110          --------------------NPEF-EAFAGWVTTKPQPPQPPPPWDQF-- 233
SGK069          --------------------DPFY-EDFLIWQASG-QPRDRPQPWFGL-- 235
SGK496          --------------------CASK-DHLWN----NVRRGARPERLP---V 225
NIK             -------------------------------------------------- 232
SGK424          ------------LICGDMPTTT---SDLYSFCILIQEVFTGELPWAGRGG 35
SURTK106        -------ELRLRL------------------------------------- 267
IKKE            ------------------------------------WSYTLPITCQLSLG 264
TBK1            ------------------------------------WSGDMPVSCSLSRG 264
MOS             -------------------------------------------DSLPG-- 251
LKB1            ---------------------------------------AIPG--DCG-- 231
CAMKK1          ---------------------------------------VFPEEPEIS-- 260
CAMKK2          ---------------------------------------EFPDQPDIA-- 252
PASK            ---------------------------------------HPPY--LVS-- 223
PIM1            ---------------------------------------FFRQR--VS-- 223
PIM3            ---------------------------------------LFRRR--VS-- 224
PIM2            ---------------------------------------HFPAH--VS-- 225
COT             -------------------------------------------ADDCS-- 223
SCYL2           -------------------------------------------LTNIP-- 266
FUSED           ---------------------------------KDPVR---WPST----- 219
ULK1            ---------------------------------KNKTLVPTIPRE----- 231
ULK2            ---------------------------------KNRSLMPSIPRE----- 231
ULK3            ---------------------------------SNRVIELPLR-----PL 225
ULK4            ---------------------------------CEDPLP-PIPKDSSRPK 230
IRE1            ---------------------------------ACSLDCLHPE-----KH 230
IRE2            ---------------------------------APCLAHLEEE-----VH 230
RNASEL          ---------------------------------LSP-------------- 187
MPSK1           ---------------------------------VQNQLSIPQS-----PR 241
PINK1           ---------------------------------QEAQL-PALPES----- 322
ALK             --------------------------------------GG---RMDPPKN 238
LTK             --------------------------------------GG---RMDPPRG 238
ROS             --------------------------------------GG---RLEPPRN 241
IGF1R           --------------------------------------GG---LLDKPDN 238
1IR3A           --------------------------------------GG---YLDQPDN 238
INSR            --------------------------------------GG---YLDQPDN 238
IRR             --------------------------------------GG---VLEELEG 238
1M14A           --------------------------------------GE---RLPQPPI 227
EGFR            --------------------------------------GE---RLPQPPI 227
HER2/ERBB2      --------------------------------------GE---RLPQPPI 227
HER4/ERBB4      --------------------------------------GE---RLPQPPI 227
HER3/ERBB3      --------------------------------------GE---RLAQPQI 227
ITK             --------------------------------------GF---RLYKPRL 220
TEC             --------------------------------------GH---RLYQPKL 220
TXK             --------------------------------------GF---RLYRPHL 220
BMX             --------------------------------------GH---RLYRPHL 220
1K2PA           --------------------------------------GL---RLYRPHL 220
BTK             --------------------------------------GL---RLYRPHL 220
CCK4            --------------------------------------GK--ARLPQPEG 236
ROR1            --------------------------------------RQ---LLPCSED 244
ROR2            --------------------------------------RQ---VLPCPDD 244
MUSK            --------------------------------------GN---ILSCPEN 252
TRKA            --------------------------------------GR---ELERPRA 242
TRKB            --------------------------------------GR---VLQRPRT 240
TRKC            --------------------------------------GR---VLERPRV 243
DDR1            --------------------------------------QGRQVYLSRPPA 266
DDR2            --------------------------------------QGRQTYLPQPAI 257
RYK             --------------------------------------GY---RIAQPIN 237
JAK1            -----------------------------------VNTLKEGKRLPCPPN 244
JAK2            -----------------------------------IELLKNNGRLPRPDG 245
JAK3            -----------------------------------LELLEEGQRLPAPPA 244
ACK             -----------------------------------HKIDKEGERLPRPED 230
TYK2            -----------------------------------TELLERGERLPRPDK 243
TNK1            -----------------------------------LQRLEDRARLPRPPP 232
EPHA1           --------------------------------------IEDGYRLPPPVD 227
EPHA10          --------------------------------------VEDGFRLPPPRN 226
FAK             --------------------------------------IENGERLPMPPN 225
EPHB6           --------------------------------------IEQEFRLPPPPG 216
EPHA2           --------------------------------------INDGFRLPTPMD 229
EPHA8           --------------------------------------VEEGYRLPAPMG 228
EPHA6           --------------------------------------IEEGYRLPAPMG 270
EPHB1           --------------------------------------IEQDYRLPPPMD 230
EPHB2           --------------------------------------IEQDYRLPPPMD 230
EPHB3           --------------------------------------VEQDYRLPPPMD 230
EPHB4           --------------------------------------IEQDYRLPPPPD 230
EPHA7           --------------------------------------IEEGYRLPAPMD 228
EPHA4           --------------------------------------IEEGYRLPPPMD 228
EPHA3           --------------------------------------VDEGYRLPPPMD 228
EPHA5           --------------------------------------VEEGYRLPSPMD 228
PYK2            --------------------------------------LEKGDRLPKPDL 225
CSK             --------------------------------------VEKGYKMDAPDG 216
CTK             --------------------------------------VEKGYRMEPPEG 214
1IEPA           --------------------------------------LEKDYRMERPEG 222
ABL             --------------------------------------LEKDYRMERPEG 222
ARG             --------------------------------------LEKGYRMEQPEG 222
BRK             --------------------------------------VDAGYRMPCPLE 221
SRM             --------------------------------------IMRGYRLPRPAA 221
FRK             --------------------------------------LAQNYRLPQPSN 224
FGR             --------------------------------------VEQGYHMPCPPG 220
FYN             --------------------------------------VERGYRMPCPQD 220
SRC             --------------------------------------VERGYRMPCPPE 220
YES             --------------------------------------VERGYRMPCPQG 220
HCK             --------------------------------------LERGYRMPRPEN 220
LYN             --------------------------------------LSQGYRMPRVEN 221
3LCK            --------------------------------------LERGYRMVRPDN 220
LCK             --------------------------------------LERGYRMVRPDN 220
BLK             --------------------------------------LERGYRMPRPDT 219
FER             --------------------------------------VERGYRMSAPQH 222
FES             --------------------------------------VEKGGRLPCPEL 224
SYK             --------------------------------------LEKGERMGCPAG 226
ZAP70           --------------------------------------IEQGKRMECPPE 226
FGFR1           --------------------------------------LKEGHRMDKPSN 247
FGFR2           --------------------------------------LKEGHRMDKPAN 247
FGFR3           --------------------------------------LKEGHRMDKPAN 247
FGFR4           --------------------------------------LREGHRMDRPPH 247
RET             --------------------------------------LKTGHRMERPDN 252
TIE1            --------------------------------------LPQGYRMEQPRN 239
1FVRA           --------------------------------------LPQGYRLEKPLN 239
TIE2            --------------------------------------LPQGYRLEKPLN 239
FLT1            --------------------------------------LREGMRMRAPEY 298
KDR             --------------------------------------LKEGTRMRAPDY 297
KDR_AVE         --------------------------------------LKEGTRMRAPDY 237
FLT4            --------------------------------------LRDGTRMRAPEL 295
FMS             --------------------------------------VKDGYQMAQPAF 299
FLT3            --------------------------------------IQNGFKMDQPFY 304
KIT             --------------------------------------IKEGFRMLSPEH 306
PDGFRA          --------------------------------------IKSGYRMAKPDH 328
PDGFRB          --------------------------------------IKRGYRMAQPAH 329
MER             --------------------------------------LLHGHRLKQPED 238
AXL             --------------------------------------LRQGNRLKQPAD 238
TYRO3           --------------------------------------LIGGNRLKQPPE 239
MET             --------------------------------------LLQGRRLLQPEY 230
RON             --------------------------------------LAQGRRLPQPEY 230
HH498           -------------------------DMAY-HHI-RP---PIGYS------ 227
LZK             -------------------------GVGS-NSLH----LPVPST------ 210
DLK             -------------------------GVGS-NSLH----LPVPSS------ 210
MLK1            -------------------------GVAM-NKLA----LPIPST------ 230
MLK3            -------------------------GVAV-NKLT----LPIPST------ 230
MLK2            -------------------------GVAM-NKLT----LPIPST------ 230
MLK4            -------------------------GVAV-NKLT----LPIPST------ 245
ZAK             -------------------------LVVE-KNER----LTIPSS------ 215
TAK1            -------------------------AV--HNGT-RP---PLIKN------ 219
KSR1            -------------------------QIGS-GEGMKRVL------TSVS-- 235
KSR2            -------------------------QMGT-G--MKPNL------SQIG-- 233
ARAF            -------------------------MVGR-GYL-SPDLSKISSN------ 228
RAF1            -------------------------MVGR-GYA-SPDLSKLYKN------ 228
BRAF            -------------------------MVGR-GYL-SPDLSKVRSN------ 228
LRRK2           -------------------------LEIQ-GK--LPD--PVKEY---GCA 224
ANKRD3          -------------------------KV--VKGH-RPELPPVCRA-RPR-- 232
SGK288          -------------------------RV--AAGM-RPSLQPVSDQ-WPS-- 231
RIPK2           -------------------------SV--SQGH-RPVINE--ESLPYDIP 243
RIPK3           -------------------------AV--CNRQNRPSLAELPQAG-PETP 233
MLKL            -------------------------LVAV-KRQQ----EPLGED------ 229
ANPA            -------------------------RVTR-G--EQPPFRPSL--ALQS-- 237
ANPB            -------------------------KVRN-G--QRPYFRPSI--DRTQ-- 238
CYGD            -------------------------RVRS----PPPLCRPLV--SMDQ-- 243
CYGF            -------------------------RLKK----PPPVYRPVV--PPEH-- 248
TBCK            --------------------------------------AEEHGCLDIIKE 224
ERK1            --------KARNYLQ-SLPS-KTK-VA-WAKLFP-K------------SD 259
3ERK            --------KARNYLL-SLPH-KNK-VP-WNRLFP-N------------AD 259
ERK2            --------KARNYLL-SLPH-KNK-VP-WNRLFP-N------------AD 259
ERK5            --------RVRAYIQ-SLPP-RQP-VP-WETVYP-G------------AD 263
1JNK            --------TVRNYVE-NRPK-YAG-LT-FPKLFP-DSLFPADSEHNKLKA 261
1PMNA           --------TVRNYVE-NRPK-YAG-LT-FPKLFP-DSLFPADSEHNKLKA 266
JNK3            --------TVRNYVE-NRPK-YAG-LT-FPKLFP-DSLFPADSEHNKLKA 266
JNK1            --------TVRTYVE-NRPK-YAG-YS-FEKLFP-DVLFPADSEHNKLKA 266
JNK2            --------TVRNYVE-NRPK-YPG-IK-FEELFP-DWIFPSESERDKIKT 266
1P38            --------SARNYIQ-SLAQ-MPK-MN-FANVFI-G------------AN 255
P38A            --------EARNYIQ-SLTQ-MPK-MN-FANVFI-G------------AN 255
P38B            --------HARTYIQ-SLPP-MPQ-KD-LSSIFR-G------------AN 263
P38D            --------AAKSYIQ-SLPQ-TPR-KD-FTQLFP-R------------AS 254
P38G            --------EAKNYMK-GLPE-LEK-KD-FASILT-N------------AS 255
NLK             ---------AKAHI-LRGPHKQPS-LPVLYTLSS-Q------------AT 260
ERK7            --------CRASVLH-QLGS-RPR-QT-LDALLPPD------------TS 281
ERK3            ---------IPVYIR-NDMT-EPH-KP-LTQLLP-G------------IS 267
ERK4            ---------MPSFVS--STW-EVK-RP-LRKLLP-E------------VN 263
ICK             --------S--SAMNFRWPQC-VP-NN-LKTLIP-N------------AS 251
MAK             --------A--SSMNFRFPQC-VP-IN-LKTLIP-N------------AS 251
PCTAIRE1        --------E--EFKTYNYPKY-RA-EA-LLSHAP-R------------LD 252
PCTAIRE2        --------E--EFKNYNFPKY-KP-EP-LINHAP-R------------LD 252
PCTAIRE3        --------S--EFRTYSFPCY-LP-QP-LINHAP-R------------LD 252
PFTAIRE1        --------P--HFKPERFTLY-SS-KN-LRQAWN-K------------LS 253
PFTAIRE2        --------P--NYNPEWFPLP-TP-RS-LHVVWN-R------------LG 253
CDC2            --------Q--DYKN-TFPKW-KP-GS-LASHVK-N------------LD 254
1HCL            --------P--DYKP-SFPKW-AR-QD-FSKVVP-P------------LD 249
CDK2            --------P--DYKP-SFPKW-AR-QD-FSKVVP-P------------LD 253
CDK3            --------P--DYKG-SFPKW-TR-KG-LEEIVP-N------------LE 253
CDK5            --------P--DYKPY--PMYPAT-TS-LVNVVP-K------------LN 253
CDK7            --------P--DYVT--FKSF-PG-IP-LHHIFS-A------------AG 254
CDK4            --------P--RG---AFPPR-GP-RP-VQSVVP-E------------ME 260
1BLXA           --------P--RQ---AFHSK-SA-QP-IEKFVT-D------------ID 258
CDK6            --------P--RQ---AFHSK-SA-QP-IEKFVT-D------------ID 258
PITSLRE         --------P--AVKKMTFSEH-PY-NN-LRKRFGAL------------LS 256
CDK10           --------P--LVGQYSLRKQ-PY-NN-LKHKFP-W------------LS 255
CDK9            --------E--LYEKLELVKG-QK-RK-VKDRLKAY-----------VRD 267
CHED            --------P--YFNTMKPKKQ-YR-RK-LREEFV-F------------IP 264
CRK7            --------P--YFNTMKPKKQ-YR-RR-LREEFS-F------------IP 264
CCRK            --------P--DYNKISFKEQ-VP-MP-LEEVLP-D------------VS 255
CDK11           --------P--EYPTLQKDFRRTT-YA-NSSLIKY------MEKHKVKPD 286
CDK8            --------P--EHSTLMKDFRRNT-YT-NCSLIKY------MEKHKVKPD 286
IKKA            -----------------PQPNSLCSLIVEPME------------------ 259
IKKB            -----------------PYPNNLNSVLAERLE------------------ 260
1PHK            ---------------------PEWDDYSDTVK------------------ 243
PHKG1           ---------------------PEWDDYSDTVK------------------ 243
PHKG2           ---------------------PEWDDRSSTVK------------------ 242
CAMK2A          ---------------------PEWDTVTPEAK------------------ 233
CAMK2B          ---------------------PEWDTVTPEAK------------------ 233
CAMK2G          ---------------------PEWDTVTPEAK------------------ 233
CAMK2D          ---------------------PEWDTVTPEAK------------------ 233
CASK            ---------------------RQWSHISESAK------------------ 239
1IA8A           ----------------------PWKKIDSAPL------------------ 228
CHK1            ----------------------PWKKIDSAPL------------------ 231
CLK1            ---------------------LDWDEHSSAGRYVSRACKPLKEFMLSQDV 285
CLK4            ---------------------LDWDEHSSAGRYVRRRCKPLKEFMLCHDE 284
CLK2            ---------------------LDWDENTSAGRYVRENCKPLRRYLTSEAE 285
CLK3            ---------------------LVWDENSSDGRYVKENCKPLKSYMLQDSL 285
MAP2K5          ---------------------------PLQLLQCIVDEDSPVLPVGE--- 212
MAP2K3          --------------------------TPFQQLKQVVEEPSPQLPADR--- 230
MAP2K6          --------------------------TPFQQLKQVVEEPSPQLPADK--- 230
MAP2K4          --------------------------SVFDQLTQVVKGDPPQLSNSEERE 234
MAP2K7          --------------------------TDFEVLTKVLQEEPPLLPGHM--G 229
MAP2K1          --------------------------AIFELLDYIVNEPPPKLPSGV--- 262
MAP2K2          --------------------------AIFELLDYIVNEPPPKLPNGV--- 266
CDKL5           -------------------------NPRFHGLRFPAVNHPQSLERRYLGI 253
CDKL1           -------------------------NQYFSGVKIPDPEDMEPLELKFPN- 252
CDKL4           -------------------------NGFFHGISIPEPEDMETLEEKFSD- 251
CDKL2           -------------------------NPVFAGVRLPEIKEREPLERRYPK- 252
CDKL3           -------------------------SPIFAGVVLPQVQHPKNARKKYPK- 251
1I09B           -------------------------N-----FKFPQIKAHPWTKVFRPR- 248
GSK3B           -------------------------NPNYTEFKFPQIKAHPWTKVFRPR- 253
1J1BA           -------------------------NPNYTEFKFPQIKAHPWTKVFRPR- 253
GSK3A           -------------------------NPNYTEFKFPQIKAHPWTKVFKSR- 253
LATS1           ---------------------------------PPQA-KLSPEA------ 277
LATS2           ---------------------------------PAQV-KLSPEA------ 277
NDR1            ---------------------------------PPEV-PISEKA------ 265
NDR2            ---------------------------------PPEV-PISEKA------ 265
MAST1           ---------------------------------PEGDEALPTEA------ 244
MAST4           ---------------------------------PEKDE------------ 238
MAST2           ---------------------------------PEGDEALPPDA------ 244
MAST3           ---------------------------------PEGDEALPADA------ 244
MRCKA           ---------------------------------PAQVTDVSENA------ 238
MRCKB           ---------------------------------PSHVTDVSEEA------ 238
DMPK2           ---------------------------------PPDVPDVPASA------ 238
DMPK1           ---------------------------------PLVDEGVPEEA------ 240
ROCK1           ---------------------------------PDD-NDISKEA------ 234
ROCK2           ---------------------------------PED-AEISKHA------ 234
CRIK            ---------------------------------PDD-PKVSSDF------ 238
MASTL           ---------------------------------PYS-SKLLKSCLETVAS 243
1O6LA           --------------------------------------LM--EEIRFPRT 221
AKT2            --------------------------------------LM--EEIRFPRT 221
AKT1            --------------------------------------LM--EEIRFPRT 222
AKT3            --------------------------------------LM--EDIKFPRT 221
MSK1            --------------------------------------LK--SEPPYPQE 233
MSK2            --------------------------------------LK--CSPPFPPR 232
P70S6K          --------------------------------------LK--CKLNLPPY 225
P70S6KB         --------------------------------------IR--GKLALPPY 225
RSK1            --------------------------------------LK--AKLGMPQF 223
RSK3            --------------------------------------LK--AKLGMPQF 223
RSK2            --------------------------------------LK--AKLGMPQF 223
RSK4            --------------------------------------LK--AKLGMPQF 223
1FOTA           --------------------------------------LN--AELRFPPF 218
1CDKA           --------------------------------------VS--GKVRFPSH 218
PKACA           --------------------------------------VS--GKVRFPSH 218
PKACB           --------------------------------------VS--GKVRFPSH 218
PKACG           --------------------------------------VS--GRVRFPSK 218
PRKX            --------------------------------------LA--GKIDFPRH 218
PRKY            --------------------------------------LA--GKLYFPR- 217
PKCA            --------------------------------------ME--HNVSYPKS 222
PKCB            --------------------------------------ME--HNVAYPKS 222
PKCG            --------------------------------------ME--QTVTYPKS 227
PKCE            --------------------------------------LH--DDVLYPVW 222
PKCH            --------------------------------------LN--DEVVYPTW 222
PKCD            --------------------------------------RV--DTPHYPRW 222
PKCT            --------------------------------------RM--DNPFYPRW 222
PKCI            --------------------------------------LE--KQIRIPRS 231
PKCZ            --------------------------------------LE--KPIRIPRF 229
PKN1            --------------------------------------VN--DEVRYPRF 223
PKN2            --------------------------------------VN--DEVRYPRF 223
PKN3            --------------------------------------VN--MDAPYPGF 223
SGK             --------------------------------------LN--KPLQLKPN 222
SGK2            --------------------------------------LH--QPLQIPGG 222
SGK3            --------------------------------------LH--KPLSLRPG 222
PKG1            --------------------------------------LRGIDMIEFPKK 223
PKG2            --------------------------------------LKGIEKMDFPRK 222
AURB            ------------------------------------------DL-KFPAS 219
AURC            ------------------------------------------DV-RFPLS 219
AURA            ------------------------------------------EF-TFPDF 219
AURORA2_AVE     ------------------------------------------EF-TFPDF 208
PLK1            ------------------------------------------EY-SIPKH 221
PLK2            ------------------------------------------RY-TMPSS 221
PLK3            ------------------------------------------HY-TLPAS 221
PLK4            ------------------------------------------DY-EMPTF 222
NEK11           ------------------------------------------DTPSLPER 227
YANK1           ----------------------------------------ETTVVTYPSA 226
YANK2           ----------------------------------------KVERVHYSST 228
YANK3           ----------------------------------------STVSVQYVPT 228
SGK494          ----------------------------------------THSDSEIPAS 220
DOMAIN2_MSK1    ---------------------------------------DFSFEGEAWKN 230
DOMAIN2_MSK2    ---------------------------------------RFSLDGEAWQG 226
DOMAIN2_RSK1    ---------------------------------------KYALSGGNWDS 226
DOMAIN2_RSK2    ---------------------------------------KFSLSGGYWNS 226
DOMAIN2_RSK3    ---------------------------------------KFTLSGGNWNT 226
DOMAIN2_RSK4    ---------------------------------------KFSLSGGNWDN 226
DRAK1           ---------------------------------------NLSYSEEEFDV 229
DRAK2           ---------------------------------------NVDYSEETFSS 229
1JKSA           ---------------------------------------NYEFEDEYFSN 231
DAPK1           ---------------------------------------NYEFEDEYFSN 231
DAPK3           ---------------------------------------NYDFDEEYFSN 231
DAPK2           ---------------------------------------SYDFDEEFFSQ 231
SGK085          ---------------------------------------RWDLEDEEFQD 224
CAMLCK          ---------------------------------------SWDFDADTFEG 224
SKMLCK          ---------------------------------------NWYFDEETFEA 224
SMMLCK          ---------------------------------------TWDFDDEAFDE 224
1KOBA           ---------------------------------------DWEFDEDAFSS 224
1TKIA           ---------------------------------------EYTFDEEAFKE 223
TTN             ---------------------------------------EYTFDEEAFKE 223
PKD1            ---------------------------------------AFMYPPNPWKE 225
PKD3            ---------------------------------------AFMYPPNPWRE 225
PKD2            ---------------------------------------AFMYPASPWSH 225
PSKH1           ---------------------------------------KYSYSGEPWPS 226
PSKH2           ---------------------------------------KYNYTGEPWPS 226
CAMK1A          ---------------------------------------EYEFDSPYWDD 225
CAMK1D          ---------------------------------------EYEFDSPYWDD 225
CAMK1B          ---------------------------------------SYEFDSPFWGD 224
CAMK1G          ---------------------------------------YYEFESPFWDD 223
CAMK4           ---------------------------------------EYYFISPWWDE 223
DCAMKL1         ---------------------------------------QVDFPSPYWDN 226
DCAMKL2         ---------------------------------------KLEFPAPYWDN 226
DCAMKL3         ---------------------------------------HFEFLPPYWDN 226
CHK2            ---------------------------------------KYNFIPEVWAE 235
MAPKAPK2        ---------------------------------------QYEFPNPEWSE 230
MAPKAPK3        ---------------------------------------QYGFPNPEWSE 229
MAPKAPK5        ---------------------------------------SFEFPEEEWSQ 251
MNK1            ---------------------------------------KYEFPDKDWAH 254
MNK2            ---------------------------------------KYEFPDKDWAH 253
VACAMKL         ---------------------------------------DYEFDSPYWDD 203
GCK             --------------------------------------RDK-------TR 226
KHS1            --------------------------------------KDK-------TK 226
KHS2            --------------------------------------KDK-------MK 226
HPK1            --------------------------------------KEK-------GK 226
MST1            --------------------------------------RKP-------EL 220
MST2            --------------------------------------RKP-------EL 220
MST3            --------------------------------------EG---------N 219
YSK1            --------------------------------------EGQ--------- 219
MST4            --------------------------------------VG---------D 219
LOK             --------------------------------------LTP-------SK 227
SLK             --------------------------------------AQP-------SR 227
MAP3K4          ----------------------------------------P-------ER 227
MAP3K2          ----------------------------------------P-------PH 230
MAP3K3          ----------------------------------------P-------SH 230
MAP3K8          ----------------------------------------P-------DH 232
MAP3K5          ----------------------------------------P-------ES 232
MAP3K7          ----------------------------------------P-------EA 223
MAP3K6          ----------------------------------------P-------SS 222
PAK1            --------------------------------------QNP-------EK 220
PAK3            --------------------------------------QNP-------ER 220
PAK2            --------------------------------------QNP-------EK 221
PAK4            --------------------------------------KNL-------HK 220
PAK5            --------------------------------------KDL-------HK 220
PAK6            --------------------------------------KNS-------HK 220
OSR1            --------------------------------------ETGVQDKEMLKK 243
STLK3           --------------------------------------ETGVEDKEMMKK 243
TAO1            --------------------------------------QSN--------E 222
TAO3            --------------------------------------QSN--------E 222
TAO2            --------------------------------------QSG--------H 222
MYO3A           --------------------------------------RQP-------EL 235
MYO3B           --------------------------------------LHP-------EK 235
ZC1/HGK         --------------------------------------KS--------KK 233
ZC3/MINK        --------------------------------------KS--------KK 233
ZC2/TNIK        --------------------------------------KS--------KK 233
ZC4/NRK         --------------------------------------KS--------SG 257
MAP3K1          ----------------------------------------P-------SH 234
GAK             ---------------------------------------NGKYSIPPHDT 244
SGK495          ---------------------------------------AAEYTIPEDGR 141
TRB1            ---------------------------------------RGQFCIP--EH 208
TRB2            ---------------------------------------RGQFNIP--ET 213
TRB3            ---------------------------------------RGAYALP--AG 211
SSTK            ---------------------------------------RGV-LYPEGLE 224
TSSK3           ---------------------------------------KG-VSFPTHLS 224
TSSK1           ---------------------------------------EHRVNFPRSKH 229
TSSK2           ---------------------------------------EHRVDFPRSKN 229
TSSK4           ---------------------------------------KE-VTFPANHT 238
HUNK            ---------------------------------------DKEMN-PLPTQ 228
SNRK            ---------------------------------------DCKYT--VPSH 222
NIM1            ---------------------------------------EGTYS--VPPH 220
MELK            ---------------------------------------RGKYD--VPKW 221
BRSK1           ---------------------------------------RGVFH--MPHF 220
BRSK2           ---------------------------------------RGVFH--MPHF 220
MARK1           ---------------------------------------RGKYR--IPFY 220
MARK2           ---------------------------------------RGKYR--IPFY 220
MARK3           ---------------------------------------RGKYR--IPFY 220
MARK4           ---------------------------------------RGKYR--VPFY 220
QIK             ---------------------------------------EGRFR--IPYF 220
SIK             ---------------------------------------EGRFR--IPFF 220
QSK             ---------------------------------------SGKFR--IPFF 220
AMPKA1          ---------------------------------------DGIFY--TPQY 221
AMPKA2          ---------------------------------------GGVFY--IPEY 221
NUAK1           ---------------------------------------SGEYR--EPTQ 221
NUAK2           ---------------------------------------NGAYR--EPPK 220
BIKE            ---------------------------------------DGNFTIPDNSR 235
AAK1            ---------------------------------------DGNFTIPDNSR 236
LIMK1           ------------------------------------VRGFLDRYC-PPN- 236
LIMK2           ------------------------------------VKLFWEKFV-PTD- 241
TESK1           ------------------------------------VPAF--RTL-VGDD 225
TESK2           ------------------------------------YDAF--QHM-VGD- 202
WNK1            ------------------------------------SGVK--PASFDKV- 227
WNK3            ------------------------------------SGIK--PASFNKV- 227
WNK2            ------------------------------------CGIK--PASFEKV- 227
WNK4            ------------------------------------SGRK--PNSFHKV- 227
NEK10           ------------------------------------EAVY--EPV-PEGI 235
NEK6            ------------------------------------QCDY--PPLPGEH- 229
NEK7            ------------------------------------QCDY--PPLPSDH- 229
NEK2            ------------------------------------EGKF--RRI-PYR- 232
NEK1            ------------------------------------SGSF--PPV-SLH- 223
NEK5            ------------------------------------QAHF--API-SPG- 224
NEK3            ------------------------------------QGCI--SPL-PSH- 222
NEK4            ------------------------------------EGKL--PAM-PRD- 224
NEK8            ------------------------------------SGTF--API-SDR- 216
NEK9            ------------------------------------QGIRA-MEVDSSQ- 225
NRBP1           ------------------------------------QEAI--SSAIQLL- 231
NRBP2           ------------------------------------EEAI--ARARHSL- 243
CLIK1           ---------------------------------LENPKMELHIPQKRRTS 296
CLIK1L          ---------------------------------LENPKMELLIPVKKK-S 292
STK33           ---------------------------------FEN---------AVWNS 234
DOMAIN2_GCN2    --------------------------------------PVTIPSD----L 229
SCYL1           ----------------------------------ALRNPGKIPKT----- 207
SCYL3           ----------------------------------------------SADV 189
DOMAIN2_JAK1    -------------------------------KERFYESRCRPVTP----S 234
DOMAIN2_TYK2    -------------------------------KEHFYQRQHRLPEP----S 249
DOMAIN2_JAK2    -------------------------------KLQFYEDRHQLPAP----K 232
DOMAIN2_JAK3    -------------------------------KLQFYEDRQQLPAP----K 228
ILK             ------------------------------MKVALEGLRPTIPPG----I 225
LRRK1           -------------------------------KKLSKGIRPVLGQPE--EV 249
PBK             ---------------------FDESDFDDEAYYAALGTRPPINMEELDES 258
WEE1            -----------------------------QWHEIRQGRLPRIPQVL---- 240
WEE1B           -----------------------------AWHHIRKGNFPDVPQEL---- 244
SGK071          -------------------HLRKSLRQSPGSLKAVLKTMEEKQIPD---- 239
PIK3R4          -------------------------------RNGHFFPEQVLNKIE---- 257
MSSK1           -----------------RHIHNLKHWGLYEVL----MEKYEWPLEQ---- 422
SRPK1           -----------------KHITKLKPWGLFEVL----VEKYEWSQEE---- 543
SRPK2           -----------------RHITKLKPWSLFDVL----VEKYGWPHED---- 575
RSKL1           --------------------------------------TLNMPEC----V 199
RSKL2           --------------------------------------QLQLPEW----L 351
SGK396          ------------------------------------DGIPKVDQ--FHXL 213
VRK1            ----------------------------------------------SKIR 241
VRK2            -------------------------------------------------- 233
VRK3            -------------------KQKQKFV---------DKPGPFVGPCGHWIR 203
BUB1            -----------------------------ECKPEGLF---------RRLP 237
BUBR1           ------------------------------------GSFWKLSQNISELK 236
SGK196          -------------------------------------------------- 222
SGK493          -------------------------------------------------- 202
                                                                  

DYRK1A          DYLKF-KDLILRMLDYDPKTRIQ-------PYYALQHSFF---------- 321
DYRK1B          DYLRF-QDLVLRMLEYEPAARIS-------PLGALQHGFF---------- 321
DYRK2           D-PLF-LDFLKQCLEWDPAVRMT-------PGQALRHPWL---------- 314
DYRK3           DY-LF-IEFLKRCLHWDPSARLT-------PAQALRHPWI---------- 314
DYRK4           YDTSF-LDFLRRCLVWEPSLRMT-------PDQALKHAWI---------- 297
HIPK1           DRREY-IDLLKKMLTIDADKRIT-------PLKTLNHQFV---------- 329
HIPK2           DRREF-IDLLKKMLTIDADKRIT-------PIETLNHPFV---------- 329
HIPK3           DRREF-VSLLKKMLLIDADLRIT-------PAETLNHPFV---------- 329
HIPK4           -------HFFKRMLTWESHERIS-------PSAALRHPFV---------- 262
PRP4            -VHQL-KDLLDQILMLDPAKRIS-------INQALQ-------------- 313
MOK             LSPQC-LSLLHAMVAYDPDERIA-------AHQALQHPYF---------- 282
1A6O            VSPEA-IDFLDKLLRYDHQERLT-------ALEAMTHPYF---------- 286
1LPUA           VSPEA-IDFLDKLLRYDHQERLT-------ALEAMTHPYF-----QQ--- 288
CK2A1           VSPEA-LDFLDKLLRYDHQSRLT-------AREAMEHPYF---------- 286
CK2A1-RS        VSPEA-LDFLDKLLRYDHQSRLT-------AREAMEHPYF---------- 286
CK2A2           VSPEA-LDLLDKLLRYDHQQRLT-------AKEAMEHPYF---------- 286
HSER            KELEV-YLLVKNCWEEDPEKRPDFKKI--E----------------TTLA 258
SLOB            PSMAV-VAVLESTLSCEACKNGM---P--TISRLLQMPLF---------- 248
CDC7            VPDEA-YDLLDKLLDLNPASRIT-------AEEALLHPFF---------- 512
1CSN            FPEEF-YKYMHYARNLAFD-------------ATPDYDYL-----QGLFS 268
CK1G1           FPEEM-ATYLRYVRRLDFF-------------EKPDYEYL---------- 264
CK1G3           FP-EM-ATYLRYVRRLDFF-------------EKPDYEYL---------- 262
CK1G2           FPEEM-ATYLRYVRRLDFF-------------EKPDYDYL---------- 263
CK1A            FPAEF-AMYLNYCRGLRFE-------------EAPDYMYL---------- 261
CK1A2           FPAEF-AMYLNYCRGLRFE-------------EVPDYMYL---------- 261
1CKJA           YPSEF-ATYLNFCRSLRFD-------------DKPDYSYL-----RQLFR 266
CK1D            YPSEF-ATYLNFCRSLRFD-------------DKPDYSYL---------- 261
CK1E            YPSEF-STYLNFCRSLRFD-------------DKPDYSYL---------- 261
TTBK1           MPSEF-HLFLDHIASLDYF-------------TKPDYQLI---------- 256
TTBK2           LPPEF-SIFLDHISSLDYF-------------TKPDYQLL---------- 256
TLK1            VSSEA-KAFIRRCLAYRKEDRFD-------VHQLANDPYL---------- 279
TLK2            VTPEA-KAFIRRCLAYRKRDRID-------VQQLACDPYL---------- 280
GPRK4           FSEDA-KSICRMLLTKNPSKRLGCRGE--GAAGVKQHPVF---------- 263
GPRK6           FSPQA-RSLCSQLLCKDPAERLGCRGG--SAREVKEHPLF---------- 263
GPRK5           FSEEA-KSICKMLLTKDAKQRLGCQEE--GAAEVKRHPFF---------- 263
RHOK            FSQAS-KDFCEALLEKDPEKRLGFRDE--TCDKLRAHPLF---------- 266
GPRK7           FTEEA-KDICRLFLAKKPEQRLRSREK--S-DDPRKHHFF---------- 264
BARK1           FSPEL-RSLLEGLLQRDVNRRLGCLGR--GAQEVKESPFF---------- 263
BARK2           FSPEL-KSLLEGLLQRDVSKRLGCHGG--GSQEVKEHSFF---------- 263
TTK             PEKDL-QDVLKCCLKRDPKQRIS-------IPELLAHPYV---------- 267
RIPK1           CPREI-ISLMKLCWEANPEARPTF--------PGIEEKF----------- 269
HASPIN          --RKI-QEFHRTMLNFSSATDLL-----------CQHSLF---------- 314
GCN2            ------KSVISWLLNHDPAKRPTA-------TEL-----LKSELL----- 412
HRI             ------AKYIQHLTRRNSSQRPSA-------IQL-----LQSELF----- 417
KIS             PAYHL-RDLIKSMLHDDPSRRIPA-------EMA-----LCSPFF----- 282
PDK1            ------RDLVEKLLVLDATKRLGC-------EEMEGYGPLKAHPFF---- 261
PKR             ------KTLLQKLLSKKPEDRPNT-------SEI-----LRTL------- 270
PEK             ------YVMVQDMLSPSPMERPEA-------INI-----IENAVF----- 485
PRPK            ------RPVLKKL------------------DEVRLRGRKRSMV------ 220
DOMAIN2_OBSCN   LSGGA-VAFLRSTLCAQPWGRPCA-------SSC-LQCPWL--------- 253
DOMAIN2_SPEG    TSQSA-TLFLRKVLSVHPWSRPSL-------QDC-LAHPWL--------- 253
LMR1            LSDRW-YEVMQFC-WLQPEQRPTA-------EEVHLLLSYL--------- 274
LMR2            YSDRW-YEVLQFC-WLSPEKRPAA-------EDVH-RLLTYL-------- 274
LMR3            YADYW-YDILQSC-WRPPAQRPSA-------SDLQLQLTYLLSERPPRPP 288
SGK307          KSGIH-VKQKDRTMNLQDIRYIL-------------------KNDLKASP 179
STLK5           FSPHF-HHFVEQCLQRNPDARPSA-------STL-LNHSFF--------- 311
STLK6           FSPAF-FSLVQLCLQQDPEKRPSA-------SSL-LSHVFF--------- 312
STLK6-RS        FSPAF-FSLVQLCLQQDPEKRPSA-------SSL-LSHVFF--------- 312
OBSCN           LSEDA-KDFIKATLQRAPQARPSA-------AQC-LSHPWF--------- 254
SPEG            LSREA-RGFLIKVL-VQDRLRPTA-------EET-LEHPWF--------- 254
TRAD            VSNAA-RDFINVILQEDFRRRPTA-------ATC-LQHPWL--------- 255
TRIO            VSQKA-KEFVCFLLQEDPAKRPSA-------ALA-LQEQWL--------- 255
SGK223          YSPGL-QQLAHLLLEADPIKRIRI-------GEA-KRVL----------- 306
SGK269          YSRGL-QQLASCLLNPNPSERILI-------SDA-KGILQCL-------- 281
ALK1            VLSGL-AQMMRECWYPNPSARLTA-------LRIKKTL------------ 288
ALK2            TLTSL-AKLMKECWYQNPSARLTA-------LRIKKTL------------ 288
IRAK4           SVEAM-YSGASQCRHEKKNKSPDI-------KKVHQLL------------ 269
BMPR2           AVRSL-KETIEDCWDQDAEARLTA-------QCAEERMAELMMIWE---- 307
TGFBR2          GIQMV-CETLTECWDHDPEARLTA-------QCVAERFS----------- 296
ACTR2           GMAML-CETIEECWDHDAEARLSA-------------------------- 281
ACTR2B          GLAQL-CVTIEECWDHDAEARLSA-------GCVEERVSL---------- 291
1B6CB           ALRVM-AKIMRECWYANGAARLTA-------LRIKKTLSQ---------- 290
TGFBR1          ALRVM-AKIMRECWYANGAARLTA-------LRIKKTL------------ 288
ALK4            ALRVM-GKMMRECWYANGAARLTA-------LRIKKTL------------ 288
ALK7            ALRVM-GRIMRECWYANGAARLTA-------LRIKKTI------------ 288
BMPR1A          CLRAV-LKLMSECWAHNPASRLTA-------LRIKKTL------------ 288
BMPR1B          CLRQM-GKLMTECWAHNPASRLTA-------LRVKKTL------------ 288
IRAK1           LGLGL-GQLACCCLHRRAKRRPPM-------TQVYERLEKL--------- 310
IRAK2           LEKGA-GRLPEDCAEALATA------------------------------ 268
IRAK3           --------LAGRCAATRAKLRPSM-------DEVLNTL------------ 279
MISR2           DPDGL-RELLEDCWDADPEARLTA-------ECVQQRLAALAHPQE---- 311
MYT1            LSSEL-RSVLVMMLEPDPKLRATA-------EALLALPVL---------- 250
SBK             -TEPA-LRMFQRLLALEPERRGPA-------KEVFRFL------------ 261
SGK110          -APPA-LALLQGLLDLDPETRSPP-------LAVLDFL------------ 262
SGK069          -AAAA-DALLRGLLDPHPRRRSAV-------IAIREHL------------ 264
SGK496          FDEEC-WQLMEACWDGDPLKRPLL-------GIVQPMLQGIMNRLCK--- 264
NIK             -----------EGLRKEPIHRVSA-------AEL----GGKVNRALQQVG 260
SGK424          PEVKA-KLEAGESPALEPRVPAPY-------QALIRAGLGLAPADRWGSL 77
SURTK106        -------------------------------------------------- 267
IKKE            LQSQL-VPILANILEVEQAKCWGF-------DQFFAETSDILQRVVVHVF 306
TBK1            LQVLL-TPVLANILEADQEKCWGF-------DQFFAETSD---------- 296
MOS             --QRL-GDVIQRCWRPSAAQRPSA-------RL----------------- 274
LKB1            --PPL-SDLLKGMLEYEPAKRFSI-------RQ----------------- 254
CAMKK1          --EEL-KDLILKMLDKNPETRIGV-------PD----------------- 283
CAMKK2          --EDL-KDLITRMLDKNPESRIVV-------PE----------------- 275
PASK            --KEL-MSLVSGLLQPVPERRTTL-------EK----------------- 246
PIM1            --SEC-QHLIRWCLALRPSDRPTF-------EE----------------- 246
PIM3            --PEC-QQLIRWCLSLRPSERPSL-------DQ----------------- 247
PIM2            --PDC-CALIRRCLAPKPSSRPSL-------EE----------------- 248
COT             --PGM-RELIEASLERNPNHRPRA-------AD----------------- 246
SCYL2           --EEV-REHVKLLLNVTPTVRPDA-------DQ----------------- 289
FUSED           ISPCF-KNFLQGLLTKDPRQRLSW-------PDLLYHPFI---------- 251
ULK1            TSAPL-RQLLLALLQRNHKDRMDF-------DEFFHHPFL---------- 263
ULK2            TSPYL-ANLLLGLLQRNQKDRMDF-------EAFFSHPFL---------- 263
ULK3            LSRDC-RDLLQRLLERDPSRRISF-------QDFFAHPWV---------- 257
ULK4            ASSDF-INLLDGLLQRDPQKRLTW-------TRLLQHSFW---------- 262
IRE1            EDVIA-RELIEKMIAMDPQKRPSA-------NDVLKHPFF---------- 262
IRE2            DKVVA-RDLVGAMLSPLPQPRPSA-------PQVLAHPFF---------- 262
RNASEL          -DEET-KDLIHRLFHPGEHVRDCL-------SDLLGHPFF---------- 218
MPSK1           HSSAL-RQLLNSMMTVDPHQRPHI-------PLLLSQL------------ 271
PINK1           VPPDV-RQLVRALLQREASKRPSA-------RVAANVL------------ 352
ALK             CPGPV-YRIMTQCWQHQPEDRPNF-------AIILERIE----------- 269
LTK             CPGPV-YRIMTQCWQHEPELRPSF-------ASILERLQ----------- 269
ROS             CPDDL-WNLMTQCWAQEPDQRPTF-------HRIQNQL------------ 271
IGF1R           CPDML-FELMRMCWQYNPKMRPSF-------LEIISSIK----------- 269
1IR3A           CPERV-TDLMRMCWQFNPKMRPTF-------LEIVNLLK----------- 269
INSR            CPERV-TDLMRMCWQFNPNMRPTF-------LEIVNLL------------ 268
IRR             CPLQL-QELMSRCWQPNPRLRPSF-------THILDSIQ----------- 269
1M14A           CTIDV-YMIMVKCWMIDADSRPKF-------RELIIEFSKMA-------- 261
EGFR            CTIDV-YMIMVKCWMIDADSRPKF-------RELIIEFS----------- 258
HER2/ERBB2      CTIDV-YMIMVKCWMIDSECRPRF-------RELVSEFS----------- 258
HER4/ERBB4      CTIDV-YMVMVKCWMIDADSRPKF-------KELAAEFS----------- 258
HER3/ERBB3      CTIDV-YMVMVKCWMIDENIRPTF-------KELANEF------------ 257
ITK             ASTHV-YQIMNHCWKERPEDRPAF-------SRLLRQL------------ 250
TEC             ASNYV-YEVMLRCWQEKPEGRPSF-------EDLLRTI------------ 250
TXK             APMSI-YEVMYSCWHEKPEGRPTF-------AELLRAVTE---------- 252
BMX             ASDTI-YQIMYSCWHELPEKRPTF-------QQLLSSIE----------- 251
1K2PA           ASEKV-YTIMYSCWHEKADERPTF-------KILLSNILDVM-------- 254
BTK             ASEKV-YTIMYSCWHEKADERPTF-------KILLSNILD---------- 252
CCK4            CPSKL-YRLMQRCWALSPKDRPSF-------SEIASAL------------ 266
ROR1            CPPRM-YSLMTECWNEIPSRRPRF-------KDIHVRLRSWEGLSSHTSS 286
ROR2            CPAWV-YALMIECWNEFPSRRPRF-------KDIHSRLRAWGNLSNYNSS 286
MUSK            CPVEL-YNLMRLCWSKLPADRPSF-------TSIHRI------------- 281
TRKA            CPPEV-YAIMRGCWQREPQQRHSI-------KDVHARLQ----------- 273
TRKB            CPQEV-YELMLGCWQREPHMRKNI-------KGIHTLL------------ 270
TRKC            CPKEV-YDVMLGCWQREPQQRLNI-------KEIYKI------------- 272
DDR1            CPQGL-YELMLRCWSRESEQRPPF-------SQLHRFL------------ 296
DDR2            CPDSV-YKLMLSCWRRDTKNRPSF-------QEIHLLL------------ 287
RYK             CPDEL-FAVMACCWALDPEERPKF-------QQLVQCL------------ 267
JAK1            CPDEV-YQLMRKCWEFQPSNRTSF-------QNLIEGFEAL--------- 277
JAK2            CPDEI-YMIMTECWNNNVNQRPSF-------RDLALRVDQI--------- 278
JAK3            CPAEV-HELMKLCWAPSPQDRPSF-------SALGPQLDMLWSGSRGCET 286
ACK             CPQDI-YNVMVQCWAHKPEDRPTF-------VALRDFL------------ 260
TYK2            CPCEV-YHLMKNCWETEASFRPTF-------------------------- 266
TNK1            SSRAL-YSLALRCWAPHPADRPSF-------SHLEGLL------------ 262
EPHA1           CPAPL-YELMKNCWAYDRARRPHF-------QKLQAHLE----------- 258
EPHA10          CPNLL-HRLMLDCWQKDPGERPRF-------SQIHS-I------------ 255
FAK             CPPTL-YSLMTKCWAYDPSRRPRF-------TELKAQL------------ 255
EPHB6           CPPGL-HLLMLDTWQKDRARRPHF-------DQLVAAF------------ 246
EPHA2           CPSAI-YQLMMQCWQQERARRPKF-------ADIVS-I------------ 258
EPHA8           CPHAL-HQLMLDCWHKDRAQRPRF-------SQIVSVL------------ 258
EPHA6           CPASL-HQLMLHCWQKERNHRPKF-------TDIVSFL------------ 300
EPHB1           CPAAL-HQLMLDCWQKDRNSRPRF-------AEIVNTL------------ 260
EPHB2           CPSAL-HQLMLDCWQKDRNHRPKF-------GQIVNTL------------ 260
EPHB3           CPTAL-HQLMLDCWVRDRNLRPKF-------SQIVNTL------------ 260
EPHB4           CPTSL-HQLMLDCWQKDRNARPRF-------PQVVSALD----------- 261
EPHA7           CPAGL-HQLMLDCWQKERAERPKF-------EQIVG-I------------ 257
EPHA4           CPIAL-HQLMLDCWQKERSDRPKF-------GQIVN-M------------ 257
EPHA3           CPAAL-YQLMLDCWQKDRNNRPKF-------EQIVS-I------------ 257
EPHA5           CPAAL-YQLMLDCWQKERNSRPKF-------DEIVN-M------------ 257
PYK2            CPPVL-YTLMTRCWDYDPSDRPRF-------TELVCSLSD---------- 257
CSK             CPPAVYE-VMKNCWHLDAAMRPSF-------LQLREQL------------ 246
CTK             CPGPVHV-LMSSCWEAEPARRPPF-------RKLAEKL------------ 244
1IEPA           CPEKVYE-LMRACWQWNPSDRPSF-------AEIHQAFET---------- 254
ABL             CPEKVYE-LMRACWQWNPSDRPSF-------AEIHQAF------------ 252
ARG             CPPKVYE-LMRACWKWSPADRPSF-------AETHQAF------------ 252
BRK             CPPSVHK-LMLTCWCRDPEQRPCF-------KALRERLS----------- 252
SRM             CPAEVYV-LMLECWRSSPEERPSF-------ATLREKL------------ 251
FRK             CPQQFYN-IMLECWNAEPKERPTF-------ETLRWKLE----------- 255
FGR             CPASLYE-AMEQTWRLDPEERPTF-------EYLQSFL------------ 250
FYN             CPISLHE-LMIHCWKKDPEERPTF-------EYLQSFL------------ 250
SRC             CPESLHD-LMCQCWRKEPEERPTF-------EYLQAF------------- 249
YES             CPESLHE-LMNLCWKKDPDERPTF-------EYIQSFL------------ 250
HCK             CPEELYN-IMMRCWKNRPEERPTF-------EYIQSVLD----------- 251
LYN             CPDELYD-IMKMCWKEKAEERPTF-------DYLQSVLD----------- 252
3LCK            CPEELYQ-LMRLCWKERPEDRPTF-------DYLRSVLE----------- 251
LCK             CPEELYQ-LMRLCWKERPEDRPTF-------DYLRSVLE----------- 251
BLK             CPPELYRGVIAECWRSRPEERPTF-------EFLQSVLE----------- 251
FER             CPEDISK-IMMKCWDYKPENRPKF-------SELQKELTI---------- 254
FES             CPDAVFR-LMEQCWAYEPGQRPSF-------STIYQELQS---------- 256
SYK             CPREM-YDLMNLCWTYDVENRPGF-------------------------- 249
ZAP70           CPPEL-YALMSDCWIYKWEDRPDF-------L------------------ 250
FGFR1           CTNEL-YMMMRDCWHAVPSQRPTF-------KQLVEDL------------ 277
FGFR2           CTNEL-YMMMRDCWHAVPSQRPTF-------KQLVEDL------------ 277
FGFR3           CTHDL-YMIMRECWHAAPSQRPTF-------KQLVEDL------------ 277
FGFR4           CPPEL-YGLMRECWHAAPSQRPTF-------KQLVEAL------------ 277
RET             CSEEM-YRLMLQCWKQEPDKRPVF-------ADISKDLEK---------- 284
TIE1            CDDEV-YELMRQCWRDRPYERPPF-------AQIALQL------------ 269
1FVRA           CDDEV-YDLMRQCWREKPYERPSF-------AQILVSLNRML-------- 273
TIE2            CDDEV-YDLMRQCWREKPYERPSF-------AQILVSL------------ 269
FLT1            STPEI-YQIMLDCWHRDPKERPRF-------AELVEKL------------ 328
KDR             TTPEM-YQTMLDCWHGEPSQRPTF-------SELVEHL------------ 327
KDR_AVE         TTPEM-YQTMLDCWHGEPSQRPTF-------SELVEHLG----------- 268
FLT4            ATPAI-RRIMLNCWSGDPKARPAF-------SELVEIL------------ 325
FMS             APKNI-YSIMQACWALEPTHRPTF-------QQICSFL------------ 329
FLT3            ATEEI-YIIMQSCWAFDSRKRPSF-------PNLTSFL------------ 334
KIT             APAEM-YDIMKTCWDADPLKRPTF-------KQIVQLI------------ 336
PDGFRA          ATSEV-YEIMVKCWNSEPEKRPSF-------YHLSEIV------------ 358
PDGFRB          ASDEI-YEIMQKCWEEKFEIRPPF-------SQLVLLL------------ 359
MER             CLDEL-YEIMYSCWRTDPLDRPTF-------SVLRL-------------- 266
AXL             CLDGL-YALMSRCWELNPQDRPSF-------TELREDLE----------- 269
TYRO3           CMEDV-YDLMYQCWSADPKQRPSF-------------------------- 262
MET             CPDPL-YEVMLKCWHPKAEMRPSF-------SELVSRIS----------- 261
RON             CPDSL-YQVMQQCWEADPAVRPTF-------------------------- 253
HH498           IPKPI-SSLLIRGWNACPEGRPEF-------SEVVMKLEECL-------- 261
LZK             CPDGF-KILMKQTWQSKPRNRPSF-------RQTLMHL------------ 240
DLK             CPDGF-KILLRQCWNSKPRNRPSF-------RQILLHL------------ 240
MLK1            CPEPF-AKLMEDCWNPDPHSRPSF-------TNILDQL------------ 260
MLK3            CPEPF-AQLMADCWAQDPHRRPDF-------ASILQQL------------ 260
MLK2            CPEPF-ARLLEECWDPDPHGRPDF-------GSILKRLEVI--------- 263
MLK4            CPEPF-AKLMKECWQQDPHIRPSF-------ALILEQL------------ 275
ZAK             CPRSF-AELLHQCWEADAKKRPSF-------KQIISI------------- 244
TAK1            LPKPI-ESLMTRCWSKDPSQRPSM-------EEIVKI------------- 248
KSR1            LGKEV-SEILSACWAFDLQERPSF-------SLLMDM------------- 264
KSR2            MGKEI-SDILLFCWAFEQEERPTF-------TKLMDM------------- 262
ARAF            CPKAM-RRLLSDCLKFQREERPLF-------PQILATI------------ 258
RAF1            CPKAM-KRLVADCVKKVKEERPLF-------PQILSSIEL---------- 260
BRAF            CPKAM-KRLMAECLKKKRDERPLF-------PQILASIEL---------- 260
LRRK2           PWPMV-EKLIKQCLKENPQERPTS-------AQVFDI------------- 253
ANKRD3          ACSHL-IRLMQRCWQGDPRVRPTF-------QEITSETED---------- 264
SGK288          EAQQM-VDLMKRCWDQDPKKRPCF-------L------------------ 255
RIPK2           HRARM-ISLIESGWAQNPDERPSF-------L------------------ 267
RIPK3           GLEGL-KELMQLCWSSEPKDRPSF-------QECLPKTDEVF-------- 267
MLKL            CPSEL-REIIDECRAHDPSVRPSV-------DEILKKLSTF--------- 262
ANPA            HLEEL-GLLMQRCWAEDPQERPPF-------QQIRLTLRK---------- 269
ANPB            LNEEL-VLLMERCWAQDPAERPDF-------GQIKGFIRR---------- 270
CYGD            APVEC-ILLMKQCWAEQPELRPSM-------DHTFDLFK----------- 274
CYGF            APPEC-LQLMKQCWAEAAEQRPTF-------DEIFNQFKT---------- 280
TBCK            LPETV-IDLLNKCLTFHPSKRPTP-------DELMKDKVF---------- 256
ERK1            --SKA-LDLLDRMLTFNPNKRITV-------EEALAHPYL---------- 289
3ERK            --SKA-LDLLDKMLTFNPHKRIEV-------EQALAHPYL---------- 289
ERK2            --SKA-LDLLDKMLTFNPHKRIEV-------EQALAHPYL---------- 289
ERK5            --RQA-LSLLGRMLRFEPSARISA-------AAALRHPFL---------- 293
1JNK            --SQA-RDLLSKMLVIDPAKRISV-------DDALQHPYI---------- 291
1PMNA           --SQA-RDLLSKMLVIDPAKRISV-------DDALQHPYINV-------- 298
JNK3            --SQA-RDLLSKMLVIDPAKRISV-------DDALQHPYI---------- 296
JNK1            --SQA-RDLLSKMLVIDASKRISV-------DEALQHPYI---------- 296
JNK2            --SQA-RDLLSKMLVIDPDKRISV-------DEALRHPYI---------- 296
1P38            --PLA-VDLLEKMLVLDSDKRITA-------AQALAHAYF---------- 285
P38A            --PLA-VDLLEKMLVLDSDKRITA-------AQALAHAYF---------- 285
P38B            --PLA-IDLLGRMLVLDSDQRVSA-------AEALAHAYF---------- 293
P38D            --PQA-ADLLEKMLELDVDKRLTA-------AQALTHPFF---------- 284
P38G            --PLA-VNLLEKMLVLDAEQRVTA-------GEALAHPYF---------- 285
NLK             --HEA-VHLLCRMLVFDPSKRISA-------KDALAHPYL---------- 290
ERK7            --PEA-LDLLRRLLVFAPDKRLSA-------TQALQHPYV---------- 311
ERK3            --REA-LDFLEQILTFSPMDRLTA-------EEALSHPYM---------- 297
ERK4            --SEA-IDFLEKILTFNPMDRLTA-------EMGLQHPYM---------- 293
ICK             --SEA-VQLLRDMLQWDPKKRPTA-------SQALRYPYF---------- 281
MAK             --NEA-IQLMTEMLNWDPKKRPTA-------SQALKHPYF---------- 281
PCTAIRE1        --SDG-ADLLTKLLQFEGRNRISA-------EDAMKHPF----------- 281
PCTAIRE2        --SEG-IELIRKFLQYESKKRVSA-------EEAMKHVY----------- 281
PCTAIRE3        --TDG-IHLLSSLLLYESKSRMSA-------EAALSHSY----------- 281
PFTAIRE1        YVNHA-EDLASKLLQCSPKNRLSA-------QAALSHEY----------- 284
PFTAIRE2        RVPEA-EDLASQMLKGFPRDRVSA-------QEALVHDY----------- 284
CDC2            --ENG-LDLLSKMLIYDPAKRISG-------KMALNHPY----------- 283
1HCL            --EDG-RSLLSQMLHYDPNKRISA-------KAALAHPF----------- 278
CDK2            --EDG-RSLLSQMLHYDPNKRISA-------KAALAHPF----------- 282
CDK3            --PEG-RDLLMQLLQYDPSQRITA-------KTALAHPY----------- 282
CDK5            --ATG-RDLLQNLLKCNPVQRISA-------EEALQHPY----------- 282
CDK7            --DDL-LDLIQGLFLFNPCARITA-------TQALKMKY----------- 283
CDK4            --ESG-AQLLLEMLTFNPHKRISA-------FRALQHSY----------- 289
1BLXA           --ELG-KDLLLKCLTFNPAKRISA-------YSALSHPY----------- 287
CDK6            --ELG-KDLLLKCLTFNPAKRISA-------YSALSHPY----------- 287
PITSLRE         --DQG-FDLMNKFLTYFPGRRISA-------EDGLKHEY----------- 285
CDK10           --EAG-LRLLHFLFMYDPKKRATA-------GDCLESSY----------- 284
CDK9            --PYA-LDLIDKLLVLDPAQRIDS-------DDALNHDFF---------- 297
CHED            --AAA-LDLFDYMLALDPSKRCTA-------EQALQCEF----------- 293
CRK7            --SAA-LDLLDHMLTLDPSKRCTA-------EQTLQSDF----------- 293
CCRK            --PQA-LDLLGQFLLYPPHQRIAA-------SKALLHQY----------- 284
CDK11           --SKV-FLLLQKLLTMDPTKRITS-------EQALQDPYF---------- 316
CDK8            --SKA-FHLLQKLLTMDPIKRITS-------EQAMQDPYF---------- 316
IKKA            -------NWLQLMLNWDPQQR------------------G---------- 274
IKKB            -------KWLQLMLMWHPRQR------------------G---------- 275
1PHK            -------DLVSRFLVVQPQKRYTA-------EEALAHPFF---------- 269
PHKG1           -------DLVSRFLVVQPQNRYTA-------EEALAHPFF---------- 269
PHKG2           -------DLISRLLQVDPEARLTA-------EQALQHPFF---------- 268
CAMK2A          -------DLINKMLTINPSKRITA-------AEALKHPWI---------- 259
CAMK2B          -------NLINQMLTINPAKRITA-------HEALKHPWV---------- 259
CAMK2G          -------NLINQMLTINPAKRITA-------DQALKHPWV---------- 259
CAMK2D          -------DLINKMLTINPAKRITA-------SEALKHPWI---------- 259
CASK            -------DLVRRMLMLDPAERITV-------YEALNHPWL---------- 265
1IA8A           -------ALLHKILVENPSARITI-------PDIKKDRW----------- 253
CHK1            -------ALLHKILVENPSARITI-------PDIKKDRW----------- 256
CLK1            EHERL-FDLIQKMLEYDPAKRITL-------REALKHPFF---------- 317
CLK4            EHEKL-FDLVRRMLEYDPTQRITL-------DEALQHPFF---------- 316
CLK2            EHHQL-FDLIESMLEYEPAKRLTL-------GEALQHPFF---------- 317
CLK3            EHVQL-FDLMRRMLEFDPAQRITL-------AEALLHPFF---------- 317
MAP2K5          FSEPF-VHFITQCMRKQPKERPAP-------EELMGHPFI---------- 244
MAP2K3          FSPEF-VDFTAQCLRKNPAERMSY-------LELMEHPFF---------- 262
MAP2K6          FSAEF-VDFTSQCLKKNSKERPTY-------PELMQHPFF---------- 262
MAP2K4          FSPSF-INFVNLCLTKDESKRPKY-------KELLKHPFI---------- 266
MAP2K7          FSGDF-QSFVKDCLTKDHRKRPKY-------NKLLEHSFI---------- 261
MAP2K1          FSLEF-QDFVNKCLIKNPAERADL-------KQLMVHAFI---------- 294
MAP2K2          FTPDF-QEFVNKCLIKNPAERADL-------KMLTNHTFI---------- 298
CDKL5           LNSVL-LDLMKNLLKLDPADRYLT-------EQCLNHPTF---------- 285
CDKL1           ISYPA-LGLLKGCLHMDPTERLTC-------EQLLHHPY----------- 283
CDKL4           VHPVA-LNFMKGCLKMNPDDRLTC-------SQLLESSY----------- 282
CDKL2           LSEVV-IDLAKKCLHIDPDKRPFC-------AELLHHDF----------- 283
CDKL3           LNGLL-ADIVHACLQIDPADRISS-------SDLLHHEYF---------- 283
1I09B           TPPEA-IALCSRLLEYTPTARLTP-------LEACAHSFF---------- 280
GSK3B           TPPEA-IALCSRLLEYTPTARLTP-------LEACAHSFF---------- 285
1J1BA           TPPEA-IALCSRLLEYTPTARLTP-------LEACAHSFFDE-------- 287
GSK3A           TPPEA-IALCSSLLEYTPSSRLSP-------LEACAHSFF---------- 285
LATS1           ------SDLIIKLCRGPE-DRLG----KNGADEIKAHPFF---------- 306
LATS2           ------RDLITKLCCSAD-HRLG----RNGADDLKAHPFF---------- 306
NDR1            ------KDLILRFCCEWE-HRIG----APGVEEIKSNSFF---------- 294
NDR2            ------KDLILRFCIDSE-NRIG----NSGVEEIKGHPFF---------- 294
MAST1           ------QLLISSLLQTNPLVRLG----AGGAFEVKQHSFF---------- 274
MAST4           -------------------------------------------------- 238
MAST2           ------QDLTSKLLHQNPLERLG----TGSAYEVKQHPFF---------- 274
MAST3           ------QDLITRLLRQSPLDRLG----TGGTHEVKQHPFF---------- 274
MRCKA           ------KDLIRRLICSRE-HRLG----QNGIEDFKKHPFF---------- 267
MRCKB           ------KDLIQRLICSRE-RRLG----QNGIEDFKKHAFF---------- 267
DMPK2           ------QDLIRQLLCRQE-ERLG----RGGLDDFRNHPFF---------- 267
DMPK1           ------RDFIQRLLCPPE-TRLG----RGGAGDFRTHPFF---------- 269
ROCK1           ------KNLICAFLTDRE-VRLG----RNGVEEIKRHLFF---------- 263
ROCK2           ------KNLICAFLTDRE-VRLG----RNGVEEIRQHPFF---------- 263
CRIK            ------LDLIQSLLCGQK-ERLK----FEG---LCCHPFF---------- 264
MASTL           NPGMP-VKCLTSNLLQSR-KRLA----TSSASS-QSHTFI---------- 276
1O6LA           LSPEA-KSLLAGLLKKDPKQRLGGG--PSDAKEVMEHRFFLS-------- 260
AKT2            LSPEA-KSLLAGLLKKDPKQRLGGG--PSDAKEVMEHRFF---------- 258
AKT1            LGPEA-KSLLSGLLKKDPKQRLGGG--SEDAKEIMQHRFF---------- 259
AKT3            LSSDA-KSLLSGLLIKDPNKRLGGG--PDDAKEIMRHSFF---------- 258
MSK1            MSALA-KDLIQRLLMKDPKKRLGCG--PRDADEIKEHLFF---------- 270
MSK2            IGPVA-QDLLQRLLCKDPKKRLGAG--PQGAQEVRNHPFF---------- 269
P70S6K          LTQEA-RDLLKKLLKRNAASRLGAG--PGDAGEVQAHPFF---------- 262
P70S6KB         LTPDA-RDLVKKFLKRNPSQRIGGG--PGDAADVQRHPFF---------- 262
RSK1            LSGEA-QSLLRALFKRNPCNRLGAG--IDGVEEIKRHPFF---------- 260
RSK3            LSTEA-QSLLRALFKRNPANRLGSG--PDGAEEIKRHVFY---------- 260
RSK2            LSPEA-QSLLRMLFKRNPANRLGAG--PDGVEEIKRHSFF---------- 260
RSK4            LSAEA-QSLLRMLFKRNPANRLGS----EGVEEIKRHLFF---------- 258
1FOTA           FNEDV-KDLLSRLITRDLSQRLGNL--QNGTEDVKNHPWFKE-------- 257
1CDKA           FSSDL-KDLLRNLLQVDLTKRFGNL--KDGVNDIKNHKWF---------- 255
PKACA           FSSDL-KDLLRNLLQVDLTKRFGNL--KNGVNDIKNHKWF---------- 255
PKACB           FSSDL-KDLLRNLLQVDLTKRFGNL--KNGVSDIKTHKWF---------- 255
PKACG           LSSDL-KDLLRSLLQVDLTKRFGNL--RNGVGDIKNHKWF---------- 255
PRKX            LDFHV-KDLIKKLLVVDRTRRLGNM--KNGANDVKHHRWF---------- 255
PRKY            -------------------------------------------------- 217
PKCA            LSKEA-VSICKGLMTKHPAKRLGCG--PEGERDVREHAFF---------- 259
PKCB            MSKEA-VAICKGLMTKHPGKRLGCG--PEGERDIKEHAFF---------- 259
PKCG            LSREA-VAICKGFLTKHPGKRLGSG--PDGEPTIRAHGFF---------- 264
PKCE            LSKEA-VSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFF---------- 261
PKCH            LHEDA-TGILKSFMTKNPTMRLGSL-TQGGEHAILRHPFF---------- 260
PKCD            ITKES-KDILEKLFEREPTKRLGVT------GNIKIHPFF---------- 255
PKCT            LEKEA-KDLLVKLFVREPEKRLGVR------GDIRQHPLF---------- 255
PKCI            LSVKA-ASVLKSFLNKDPKERLGCH-PQTGFADIQGHPFF---------- 269
PKCZ            LSVKA-SHVLKGFLNKDPKERLGCR-PQTGFSDIKSHAFF---------- 267
PKN1            LSAEA-IGIMRRLLRRNPERRLGSS--ERDAEDVKKQPFF---------- 260
PKN2            LSTEA-ISIMRRLLRRNPERRLGAS--EKDAEDVKKHPFF---------- 260
PKN3            LSVQG-LEFIQKLLQKCPEKRLGAG--EQDAEEIKVQPFF---------- 260
SGK             ITNSA-RHLLEGLLQKDRTKRLGA---KDDFMEIKSHVFF---------- 258
SGK2            RTVAA-CDLLQSLLHKDQRQRLGS---KADFLEIKNHVFF---------- 258
SGK3            VSLTA-WSILEELLEKDRQNRLGA---KEDFLEIQNHPFF---------- 258
PKG1            IAKNA-ANLIKKLCRDNPSERLGNL--KNGVKDIQKHKWF---------- 260
PKG2            ITRRP-EDLIRRLCRQNPTERLGNL--KNGINDIKKHRWL---------- 259
AURB            VPTGA-QDLISKLLRHNPSERLPL-------AQVSAHPWV---------- 251
AURC            MPLGA-RDLISRLLRYQPLERLPL-------AQILKHPWV---------- 251
AURA            VTEGA-RDLISRLLKHNPSQRPML-------REVLEHPWI---------- 251
AURORA2_AVE     VTEGA-RDLISRLLKHNPSQRPML-------REVLEHPWI---------- 240
PLK1            INPVA-ASLIQKMLQTDPTARPTI-------NELLNDEFF---------- 253
PLK2            LLAPA-KHLIASMLSKNPEDRPSL-------DDIIRHDFF---------- 253
PLK3            LSLPA-RQLLAAILRASPRDRPSI-------DQILRHDFF---------- 253
PLK4            LSIEA-KDLIHQLLRRNPADRLSL-------SSVLDHPFM---------- 254
NEK11           YPKEL-NAIMESMLNKNPSLRPSA-------IEILKIPYL---------- 259
YANK1           WSQEM-VSLLKKLLEPNPDQRFSQ-------LSDVQNFPYM--------- 259
YANK2           WCKGM-VALLRKLLTKDPESRVSS-------LHDIQSVPYL--------- 261
YANK3           WSKEM-VALLRKLLTVNPEHRLSS-------LQDVQAAPAL--------- 261
SGK494          LNQGL-SLLLHELLCQNPLHRLRY-------LHHFQVHPFF--------- 253
DOMAIN2_MSK1    VSQEA-KDLIQGLLTVDPNKRLKM-------SGLRYNEWL---------- 262
DOMAIN2_MSK2    VSEEA-KELVRGLLTVDPAKRLKL-------EGLRGSSWL---------- 258
DOMAIN2_RSK1    ISDAA-KDVVSKMLHVDPHQRLTA-------MQVLKHPWV---------- 258
DOMAIN2_RSK2    VSDTA-KDLVSKMLHVDPHQRLTA-------ALVLRHPWI---------- 258
DOMAIN2_RSK3    VSETA-KDLVSKMLHVDPHQRLTA-------KQVLQHPWV---------- 258
DOMAIN2_RSK4    ISDGA-KDLLSHMLHMDPHQRYTA-------EQILKHSWI---------- 258
DRAK1           LSESA-VDFIRTLLVKKPEDRATA-------EECLKHPWL---------- 261
DRAK2           VSQLA-TDFIQSLLVKNPEKRPTA-------EICLSHSWL---------- 261
1JKSA           TSALA-KDFIRRLLVKDPKKRMTI-------QDSLQHPWIKP-------- 265
DAPK1           TSALA-KDFIRRLLVKDPKKRMTI-------QDSLQHPWI---------- 263
DAPK3           TSELA-KDFIRRLLVKDPKRRMTI-------AQSLEHSWI---------- 263
DAPK2           TSELA-KDFIRKLLVKETRKRLTI-------QEALRHPWI---------- 263
SGK085          ISEEA-KEFISKLLIKEKSWRISA-------SEALKHPWL---------- 256
CAMLCK          LSEEA-KDFVSRLLVKEKSCRMSA-------TQCLKHEWL---------- 256
SKMLCK          VSDEA-KDFVSNLIVKDQRARMNA-------AQCLAHPWL---------- 256
SMMLCK          ISDDA-KDFISNLLKKDMKNRLDC-------TQCLQHPWL---------- 256
1KOBA           VSPEA-KDFIKNLLQKEPRKRLTV-------HDALEHPWL---------- 256
1TKIA           ISIEA-MDFVDRLLVKERKSRMTA-------SEALQHPWL---------- 255
TTN             ISIEA-MDFVDRLLVKERKSRMTA-------SEALQHPWL---------- 255
PKD1            ISHEA-IDLINNLLQVKMRKRYSV-------DKTLSHPWL---------- 257
PKD3            ISGEA-IDLINNLLQVKMRKRYSV-------DKSLSHPWL---------- 257
PKD2            ISAGA-IDLINNLLQVKMRKRYSV-------DKSLSHPWL---------- 257
PSKH1           VSNLA-KDFIDRLLTVDPGARMTA-------LQALRHPWV---------- 258
PSKH2           ISHLA-KDFIDKLLILEAGHRMSA-------GQALDHPWV---------- 258
CAMK1A          ISDSA-KDFIRHLMEKDPEKRFTC-------EQALQHPWI---------- 257
CAMK1D          ISDSA-KDFIRNLMEKDPNKRYTC-------EQAARHPWI---------- 257
CAMK1B          ISESA-KDFIRHLLERDPQKRFTC-------QQALRHLWV---------- 256
CAMK1G          ISESA-KDFICHLLEKDPNERYTC-------EKALSHPWI---------- 255
CAMK4           VSLNA-KDLVRKLIVLDPKKRLTT-------FQALQHPWV---------- 255
DCAMKL1         VSDSA-KELITMMLLVDVDQRFSA-------VQVLEHPWV---------- 258
DCAMKL2         ITDSA-KELISQMLQVNVEARCTA-------GQILSHPWV---------- 258
DCAMKL3         ISDAA-KDLVSRLLVVDPKKRYTA-------HQVLQHPWI---------- 258
CHK2            VSEKA-LDLVKKLLVVDPKARFTT-------EEALRHPWL---------- 267
MAPKAPK2        VSEEV-KMLIRNLLKTEPTQRMTI-------TEFMNHPWI---------- 262
MAPKAPK3        VSEDA-KQLIRLLLKTDPTERLTI-------TQFMNHPWI---------- 261
MAPKAPK5        ISEMA-KDVVRKLLKVKPERRLTI-------EGVLDHPWL---------- 283
MNK1            ISSEA-KDLISKLLVRDAKQRLSA-------AQVLQHPWV---------- 286
MNK2            ISCAA-KDLISKLLVRDAKQRLSA-------AQVLQHPWV---------- 285
VACAMKL         ISQAA-KDLVTRLMEVEQDQRITA-------EEAISHEWI---------- 235
GCK             WTQNF-HHFLKLALTKNPKKRPTA-------EKLLQHPFT---------- 258
KHS1            WSSTF-HNFVKIALTKNPKKRPTA-------ERLLTHTFV---------- 258
KHS2            WSNSF-HHFVKMALTKNPKKRPTA-------EKLLQHPFV---------- 258
HPK1            WSAAF-HNFIKVTLTKSPKKRPSA-------TKMLSHQLV---------- 258
MST1            WSDNF-TDFVKQCLVKSPEQRATA-------TQLLQHPFV---------- 252
MST2            WSDDF-TDFVKKCLVKNPEQRATA-------TQLLQHPFI---------- 252
MST3            YSKPL-KEFVEACLNKEPSFRPTA-------KELLKHKFI---------- 251
YSK1            HSKPF-KEFVEACLNKDPRFRPTA-------KELLKHKFI---------- 251
MST4            FTKSF-KEFIDACLNKDPSFRPTA-------KELLKHKFI---------- 251
LOK             WSVEF-RDFLKIALDKNPETRPSA-------AQLLEHPFV---------- 259
SLK             WSSNF-KDFLKKCLEKNVDARWTT-------SQLLQHPFV---------- 259
MAP3K4          LSPEG-KDFLSHCLESDPKMRWTA-------SQLLDHSFV---------- 259
MAP3K2          VSDYT-RDFLKRIFV-EAKLRPSA-------DELLRHMFV---------- 261
MAP3K3          ISEHG-RDFLRRIFV-EARQRPSA-------EELLTHHFA---------- 261
MAP3K8          FSENA-ADFVRMCLTRDQHERPSA-------LQLLKHSFL---------- 264
MAP3K5          MSAEA-KAFILKCFEPDPDKRACA-------NDLLVDEFL---------- 264
MAP3K7          LSAEA-RAFILSCFEPDPHKRATT-------AELLREGFL---------- 255
MAP3K6          LSAEA-QAFLLRTFEPDPRLRASA-------QTLLGDPFL---------- 254
PAK1            LSAIF-RDFLNRCLDMDVEKRGSA-------KELLQHQFL---------- 252
PAK3            LSAVF-RDFLNRCLEMDVDRRGSA-------KELLQHPFL---------- 252
PAK2            LSPIF-RDFLNRCLEMDVEKRGSA-------KELLQHPFL---------- 253
PAK4            VSPSL-KGFLDRLLVRDPAQRATA-------AELLKHPFL---------- 252
PAK5            VSSVL-RGFLDLMLVREPSQRATA-------QELLGHPFL---------- 252
PAK6            VSPVL-RDFLERMLVRDPQERATA-------QELLDHPFL---------- 252
OSR1            YGKSF-RKMISLCLQKDPEKRPTA-------AELLRHKFF---------- 275
STLK3           YGKSF-RKLLSLCLQKDPSKRPTA-------AELLKCKFF---------- 275
TAO1            WSDYF-RNFVDSCLQKIPQDRPTS-------EELLKHIFV---------- 254
TAO3            WTDSF-RRFVDYCLQKIPQERPTS-------AELLRHDFV---------- 254
TAO2            WSEYF-RNFVDSCLQKIPQDRPTS-------EVLLKHRFV---------- 254
MYO3A           WSAEF-NDFISKCLTKDYEKRPTV-------SELLQHKFI---------- 267
MYO3B           WCEEF-NHFISQCLIKDFERRPSV-------THLLDHPFI---------- 267
ZC1/HGK         WSKKF-FSFIEGCLVKNYMQRPST-------EQLLKHPFI---------- 265
ZC3/MINK        WSKKF-IDFIDTCLIKTYLSRPPT-------EQLLKFPFI---------- 265
ZC2/TNIK        WSKKF-QSFIESCLVKNHSQRPAT-------EQLMKHPFI---------- 265
ZC4/NRK         WSRKF-HNFMEKCTIKNFLFRPTS-------ANMLQHPFV---------- 289
MAP3K1          LSPGL-RDVALRCLELQPQDRPPS-------RELLKHPVF---------- 266
GAK             QYTVF-HSLIRAMLQVNPEERLSI-------AEVVHQ--L---------- 274
SGK495          VSENT-VCLIRKLLVLDPQQRLAA-------ADVLEAL------------ 171
TRB1            ISPKA-RCLIRSLLRREPSERLTA-------PEILLHPWF---------- 240
TRB2            LSPKA-KCLIRSILRREPSERLTS-------QEILDHPWF---------- 245
TRB3            LSAPA-RCLVRCLLRREPAERLTA-------TGILLHPWL---------- 243
SSTK            LSERC-KALIAELLQFSPSARPSA-------GQVARNCWL---------- 256
TSSK3           ISADC-QDLLKRLLEPDMILRPSI-------EEVSWHPWL---------- 256
TSSK1           LTGEC-KDLIYHMLQPDVNRRLHI-------DEILSHCWM---------- 261
TSSK2           LTCEC-KDLIYRMLQPDVSQRLHI-------DEILSHSWL---------- 261
TSSK4           ISQEC-KNLILQMLR-QATKRATI-------LDIIKDSWV---------- 269
HUNK            LSTGA-ISFLRSLLEPDPVKRPNI-------QQALANRWL---------- 260
SNRK            VSKEC-KDLITRMLQRDPKRRASL-------EEIENHPWL---------- 254
NIM1            VSEPC-HRLIRGVLQQIPTERYGI-------DCIMNDEWM---------- 252
MELK            LSPSS-ILLLQQMLQVDPKKRISM-------KNLLNHPWI---------- 253
BRSK1           IPPDC-QSLLRGMIEVEPEKRLSL-------EQIQKHPWY---------- 252
BRSK2           IPPDC-QSLLRGMIEVDAARRLTL-------EHIQKHIWY---------- 252
MARK1           MSTDC-ENLLKKLLVLNPIKRGSL-------EQIMKDRWM---------- 252
MARK2           MSTDC-ENLLKKFLILNPSKRGTL-------EQIMKDRWM---------- 252
MARK3           MSTDC-ENLLKRFLVLNPIKRGTL-------EQIMKDRWI---------- 252
MARK4           MSTDC-ESILRRFLVLNPAKRCTL-------EQIMKDKWI---------- 252
QIK             MSEDC-EHLIRRMLVLDPSKRLTI-------AQIKEHKWM---------- 252
SIK             MSQDC-ESLIRRMLVVDPARRITI-------AQIRQHRWM---------- 252
QSK             MSTEC-EHLIRHMLVLDPNKRLSM-------EQICKHKWM---------- 252
AMPKA1          LNPSV-ISLLKHMLQVDPMKRASI-------KDIREHEWF---------- 253
AMPKA2          LNRSV-ATLLMHMLQVDPLKRATI-------KDIREHEWF---------- 253
NUAK1           PS-DA-RGLIRWMLMVNPDRRATI-------EDIANHWWV---------- 252
NUAK2           PSDCL-XGLIRWLLMVNPTRRATL-------EDVASHWWV---------- 252
BIKE            YSRNI-HCLIRFMLEPDPEHRPDI-------FQVSYFAFKFAKKDCPVSN 277
AAK1            YSQDM-HCLIRYMLEPDPDKRPDI-------YQVSYFSFKLLKKECP--- 275
LIMK1           CPPSF-FPITVRCCDLDPEKRPSF-------VKLEHWL------------ 266
LIMK2           CPPAF-FPLAAICCRLEPESRPAF-------SKLEDSF------------ 271
TESK1           CPLPF-LLLAIHCCNLEPSTRAPF-------TEITQHLEWI--------- 258
TESK2           CPPDF-LQLTFNCCNMDPKLRPSF-------VEIGKTL------------ 232
WNK1            AIPEV-KEIIEGCIRQNKDERYSI-------KDLLNHAFF---------- 259
WNK3            TDPEV-KEIIEGCIRQNKSERLSI-------RDLLNHAFF---------- 259
WNK2            HDPEI-KEIIGECICKNKEERYEI-------KDLLSHAFF---------- 259
WNK4            KIPEV-KEIIEGCIRTDKNERFTI-------QDLLAHAFF---------- 259
NEK10           YSEKV-TDTISRCLTPDAEARPDI-------VEVSSMISD---------- 267
NEK6            YSEKL-RELVSMCICPDPHQRPGS-------LEQLRPQGSAGSPKGCPAL 271
NEK7            YSEEL-RQLVNMCINPDPEKRPDV-------------------------- 252
NEK2            YSDEL-NEIITRMLNLKDYHRPSV-------EEILENPLI---------- 264
NEK1            YSYDL-RSLVSQLFKRNPRDRPSV-------NSILEKGFI---------- 255
NEK5            FSREL-HSLISQLFQVSPRDRPSI-------NSILKRPFL---------- 256
NEK3            YSYEL-QFLVKQMFKRNPSHRPSA-------TTLLSRGIV---------- 254
NEK4            YSPEL-AELIRTMLSKRPEERPSV-------RSILRQPYI---------- 256
NEK8            YSPEL-RQLVLSLLSLEPAQRPPL-------SHIMAQPLC---------- 248
NEK9            YSLEL-IQMVHSCLDQDPEQRPTA-------DELLDRPLL---------- 257
NRBP1           EDPLQ-REFIQKCLQSEPARRPTA-------RELLFHPALF--------- 264
NRBP2           SDPNM-REFILCCLARDPARRPSA-------HSLLFHRVLF--------- 276
CLIK1           MSEGI-KQLLKDMLAANPQDRPDA-------FELETRMDQV--------- 329
CLIK1L          MNGRM-KQLIKEMLAANPQDRPDA-------FELELRLVQIAFKDSSWE- 333
STK33           ISDCA-KSVLKQLMKVDPAHRITA-------KEL---------LDNQWL- 266
DOMAIN2_GCN2    P-ADF-QDFLKKCVCLDDKERWSP---------------QQLLKHSFI-- 260
SCYL1           ----L-VPHYCELVGANPKVRPNP---------------ARFLQ------ 231
SCYL3           LSSFQ-QTLHSTLLNPIPKCRPAL---------------CTLLSHDFF-- 221
DOMAIN2_JAK1    C-KEL-ADLMTRCMNYDPNQRPFF---------------RAIMRDINK-- 265
DOMAIN2_TYK2    C-PQL-ATLTSQCLTYEPTQRPSF---------------RTILRDL---- 278
DOMAIN2_JAK2    W-AEL-ANLINNCMDYEPDFRPSF---------------RAIIRDLNSLF 265
DOMAIN2_JAK3    W-TEL-ALLIQQCMAYEPVQRPSF---------------RAVIRDLNSLI 261
ILK             S-PHV-CKLMKICMNEDPAKRPKF---------------DMIVPILEKM- 257
LRRK1           QFRRL-QALMMECWDTKPEKRPLA---------------LSVVSQMKDPT 283
PBK             Y-QKV-IELFSVCTNEDPKDRPSA---------------AHIVEAL---- 287
WEE1            -SQEF-TELLKVMIHPDPERRPSA---------------MALVKHSVL-- 271
WEE1B           -SESF-SSLLKNMIQPDAEQRPSA---------------AALARNTVL-- 275
SGK071          -VETF-RNLLPLMLQIDPSDRITI---------------KDVVHITF--- 269
PIK3R4          -DHSI-RELVTQMIHREPDKRLEA---------------EDYLK------ 284
MSSK1           -ATQF-SAFLLPMMEYIPEKRASA---------------ADCLQHPWL-- 453
SRPK1           -AAGF-TDFLLPMLELIPEKRATA---------------AECLRHPWL-- 574
SRPK2           -AAQF-TDFLIPMLEMVPEKRASA---------------GECLRHPWL-- 606
RSKL1           S-EEA-RSLIQQLLQFNPLERLGA----------GVAGVEDIKSHPFF-- 235
RSKL2           S-RPA-ASLLTELLQFEPTRRLGM----------GEGGVSKLKSHPFF-- 387
SGK396          -DDKV-KSLLCSLICYRSSMTA-----------------EQVLNAECF-- 242
VRK1            YRENI-ASLMDKCFPEKNKPGEIA---------------KYM-------- 267
VRK2            --TAK-TNLLDELPQSVLKWAPSG---------------SSCCEIAQFL- 264
VRK3            PSETL-QKYLKVVMALTYEEKPP--------YAMLRNNLEALLQDL---- 240
BUB1            HLDMW-NEFFHVMLNIPDCHHLPS-------LDLLRQKL----------- 268
BUBR1           DGELW-NKFFVRILNANDEATVSV---------------LGELAA----- 265
SGK196          -RFHL-FDIHKACKSQTPSERPTA---------------QDVLETY---- 251
SGK493          -AYRF-FFTYLLPHSAPPSLRPLL---------------DSIV------- 228
                                                                  

DYRK1A          -------------------------------- 321
DYRK1B          -------------------------------- 321
DYRK2           -------------------------------- 314
DYRK3           -------------------------------- 314
DYRK4           -------------------------------- 297
HIPK1           -------------------------------- 329
HIPK2           -------------------------------- 329
HIPK3           -------------------------------- 329
HIPK4           -------------------------------- 262
PRP4            -------------------------------- 313
MOK             -------------------------------- 282
1A6O            -------------------------------- 286
1LPUA           -------------------------------- 288
CK2A1           -------------------------------- 286
CK2A1-RS        -------------------------------- 286
CK2A2           -------------------------------- 286
HSER            KIFGLFHDQKNESYM----------------- 273
SLOB            -------------------------------- 248
CDC7            -------------------------------- 512
1CSN            K------------------------------- 269
CK1G1           -------------------------------- 264
CK1G3           -------------------------------- 262
CK1G2           -------------------------------- 263
CK1A            -------------------------------- 261
CK1A2           -------------------------------- 261
1CKJA           NLFHRQGFSYDYVFDWNMLKFG---------- 288
CK1D            -------------------------------- 261
CK1E            -------------------------------- 261
TTBK1           -------------------------------- 256
TTBK2           -------------------------------- 256
TLK1            -------------------------------- 279
TLK2            -------------------------------- 280
GPRK4           -------------------------------- 263
GPRK6           -------------------------------- 263
GPRK5           -------------------------------- 263
RHOK            -------------------------------- 266
GPRK7           -------------------------------- 264
BARK1           -------------------------------- 263
BARK2           -------------------------------- 263
TTK             -------------------------------- 267
RIPK1           -------------------------------- 269
HASPIN          -------------------------------- 314
GCN2            -------------------------------- 412
HRI             -------------------------------- 417
KIS             -------------------------------- 282
PDK1            -------------------------------- 261
PKR             -------------------------------- 270
PEK             -------------------------------- 485
PRPK            -------------------------------- 220
DOMAIN2_OBSCN   -------------------------------- 253
DOMAIN2_SPEG    -------------------------------- 253
LMR1            -------------------------------- 274
LMR2            -------------------------------- 274
LMR3            PPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFP 320
SGK307          EVDFT--------------------------- 184
STLK5           -------------------------------- 311
STLK6           -------------------------------- 312
STLK6-RS        -------------------------------- 312
OBSCN           -------------------------------- 254
SPEG            -------------------------------- 254
TRAD            -------------------------------- 255
TRIO            -------------------------------- 255
SGK223          -------------------------------- 306
SGK269          -------------------------------- 281
ALK1            -------------------------------- 288
ALK2            -------------------------------- 288
IRAK4           -------------------------------- 269
BMPR2           -------------------------------- 307
TGFBR2          -------------------------------- 296
ACTR2           -------------------------------- 281
ACTR2B          -------------------------------- 291
1B6CB           -------------------------------- 290
TGFBR1          -------------------------------- 288
ALK4            -------------------------------- 288
ALK7            -------------------------------- 288
BMPR1A          -------------------------------- 288
BMPR1B          -------------------------------- 288
IRAK1           -------------------------------- 310
IRAK2           -------------------------------- 268
IRAK3           -------------------------------- 279
MISR2           -------------------------------- 311
MYT1            -------------------------------- 250
SBK             -------------------------------- 261
SGK110          -------------------------------- 262
SGK069          -------------------------------- 264
SGK496          -------------------------------- 264
NIK             GLKSPWR------------------------- 267
SGK424          -------------------------------- 77
SURTK106        -------------------------------- 267
IKKE            SLSQAVLHHIYI-------------------- 318
TBK1            -------------------------------- 296
MOS             ----LLVDLTS--------------------- 281
LKB1            ----IRQHSWF--------------------- 261
CAMKK1          ----IKLHPWV--------------------- 290
CAMKK2          ----IKLHPWV--------------------- 282
PASK            ----LVTDPWV--------------------- 253
PIM1            ----IQNHPWM--------------------- 253
PIM3            ----IAAHPWM--------------------- 254
PIM2            ----ILLDPWM--------------------- 255
COT             ----LLKHEAL--------------------- 253
SCYL2           ----MTKIPFF--------------------- 296
FUSED           -------------------------------- 251
ULK1            -------------------------------- 263
ULK2            -------------------------------- 263
ULK3            -------------------------------- 257
ULK4            -------------------------------- 262
IRE1            -------------------------------- 262
IRE2            -------------------------------- 262
RNASEL          -------------------------------- 218
MPSK1           -------------------------------- 271
PINK1           -------------------------------- 352
ALK             -------------------------------- 269
LTK             -------------------------------- 269
ROS             -------------------------------- 271
IGF1R           -------------------------------- 269
1IR3A           -------------------------------- 269
INSR            -------------------------------- 268
IRR             -------------------------------- 269
1M14A           -------------------------------- 261
EGFR            -------------------------------- 258
HER2/ERBB2      -------------------------------- 258
HER4/ERBB4      -------------------------------- 258
HER3/ERBB3      -------------------------------- 257
ITK             -------------------------------- 250
TEC             -------------------------------- 250
TXK             -------------------------------- 252
BMX             -------------------------------- 251
1K2PA           -------------------------------- 254
BTK             -------------------------------- 252
CCK4            -------------------------------- 266
ROR1            TTPSGGNATTQTTSLSASPVS----------- 307
ROR2            AQTSGASNTTQTSSLSTSPVS----------- 307
MUSK            -------------------------------- 281
TRKA            -------------------------------- 273
TRKB            -------------------------------- 270
TRKC            -------------------------------- 272
DDR1            -------------------------------- 296
DDR2            -------------------------------- 287
RYK             -------------------------------- 267
JAK1            -------------------------------- 277
JAK2            -------------------------------- 278
JAK3            HAFTAHPEGKHHSLS----------------- 301
ACK             -------------------------------- 260
TYK2            -------------------------------- 266
TNK1            -------------------------------- 262
EPHA1           -------------------------------- 258
EPHA10          -------------------------------- 255
FAK             -------------------------------- 255
EPHB6           -------------------------------- 246
EPHA2           -------------------------------- 258
EPHA8           -------------------------------- 258
EPHA6           -------------------------------- 300
EPHB1           -------------------------------- 260
EPHB2           -------------------------------- 260
EPHB3           -------------------------------- 260
EPHB4           -------------------------------- 261
EPHA7           -------------------------------- 257
EPHA4           -------------------------------- 257
EPHA3           -------------------------------- 257
EPHA5           -------------------------------- 257
PYK2            -------------------------------- 257
CSK             -------------------------------- 246
CTK             -------------------------------- 244
1IEPA           -------------------------------- 254
ABL             -------------------------------- 252
ARG             -------------------------------- 252
BRK             -------------------------------- 252
SRM             -------------------------------- 251
FRK             -------------------------------- 255
FGR             -------------------------------- 250
FYN             -------------------------------- 250
SRC             -------------------------------- 249
YES             -------------------------------- 250
HCK             -------------------------------- 251
LYN             -------------------------------- 252
3LCK            -------------------------------- 251
LCK             -------------------------------- 251
BLK             -------------------------------- 251
FER             -------------------------------- 254
FES             -------------------------------- 256
SYK             -------------------------------- 249
ZAP70           -------------------------------- 250
FGFR1           -------------------------------- 277
FGFR2           -------------------------------- 277
FGFR3           -------------------------------- 277
FGFR4           -------------------------------- 277
RET             -------------------------------- 284
TIE1            -------------------------------- 269
1FVRA           -------------------------------- 273
TIE2            -------------------------------- 269
FLT1            -------------------------------- 328
KDR             -------------------------------- 327
KDR_AVE         -------------------------------- 268
FLT4            -------------------------------- 325
FMS             -------------------------------- 329
FLT3            -------------------------------- 334
KIT             -------------------------------- 336
PDGFRA          -------------------------------- 358
PDGFRB          -------------------------------- 359
MER             -------------------------------- 266
AXL             -------------------------------- 269
TYRO3           -------------------------------- 262
MET             -------------------------------- 261
RON             -------------------------------- 253
HH498           -------------------------------- 261
LZK             -------------------------------- 240
DLK             -------------------------------- 240
MLK1            -------------------------------- 260
MLK3            -------------------------------- 260
MLK2            -------------------------------- 263
MLK4            -------------------------------- 275
ZAK             -------------------------------- 244
TAK1            -------------------------------- 248
KSR1            -------------------------------- 264
KSR2            -------------------------------- 262
ARAF            -------------------------------- 258
RAF1            -------------------------------- 260
BRAF            -------------------------------- 260
LRRK2           -------------------------------- 253
ANKRD3          -------------------------------- 264
SGK288          -------------------------------- 255
RIPK2           -------------------------------- 267
RIPK3           -------------------------------- 267
MLKL            -------------------------------- 262
ANPA            -------------------------------- 269
ANPB            -------------------------------- 270
CYGD            -------------------------------- 274
CYGF            -------------------------------- 280
TBCK            -------------------------------- 256
ERK1            -------------------------------- 289
3ERK            -------------------------------- 289
ERK2            -------------------------------- 289
ERK5            -------------------------------- 293
1JNK            -------------------------------- 291
1PMNA           -------------------------------- 298
JNK3            -------------------------------- 296
JNK1            -------------------------------- 296
JNK2            -------------------------------- 296
1P38            -------------------------------- 285
P38A            -------------------------------- 285
P38B            -------------------------------- 293
P38D            -------------------------------- 284
P38G            -------------------------------- 285
NLK             -------------------------------- 290
ERK7            -------------------------------- 311
ERK3            -------------------------------- 297
ERK4            -------------------------------- 293
ICK             -------------------------------- 281
MAK             -------------------------------- 281
PCTAIRE1        -------------------------------- 281
PCTAIRE2        -------------------------------- 281
PCTAIRE3        -------------------------------- 281
PFTAIRE1        -------------------------------- 284
PFTAIRE2        -------------------------------- 284
CDC2            -------------------------------- 283
1HCL            -------------------------------- 278
CDK2            -------------------------------- 282
CDK3            -------------------------------- 282
CDK5            -------------------------------- 282
CDK7            -------------------------------- 283
CDK4            -------------------------------- 289
1BLXA           -------------------------------- 287
CDK6            -------------------------------- 287
PITSLRE         -------------------------------- 285
CDK10           -------------------------------- 284
CDK9            -------------------------------- 297
CHED            -------------------------------- 293
CRK7            -------------------------------- 293
CCRK            -------------------------------- 284
CDK11           -------------------------------- 316
CDK8            -------------------------------- 316
IKKA            -------------------------------- 274
IKKB            -------------------------------- 275
1PHK            -------------------------------- 269
PHKG1           -------------------------------- 269
PHKG2           -------------------------------- 268
CAMK2A          -------------------------------- 259
CAMK2B          -------------------------------- 259
CAMK2G          -------------------------------- 259
CAMK2D          -------------------------------- 259
CASK            -------------------------------- 265
1IA8A           -------------------------------- 253
CHK1            -------------------------------- 256
CLK1            -------------------------------- 317
CLK4            -------------------------------- 316
CLK2            -------------------------------- 317
CLK3            -------------------------------- 317
MAP2K5          -------------------------------- 244
MAP2K3          -------------------------------- 262
MAP2K6          -------------------------------- 262
MAP2K4          -------------------------------- 266
MAP2K7          -------------------------------- 261
MAP2K1          -------------------------------- 294
MAP2K2          -------------------------------- 298
CDKL5           -------------------------------- 285
CDKL1           -------------------------------- 283
CDKL4           -------------------------------- 282
CDKL2           -------------------------------- 283
CDKL3           -------------------------------- 283
1I09B           -------------------------------- 280
GSK3B           -------------------------------- 285
1J1BA           -------------------------------- 287
GSK3A           -------------------------------- 285
LATS1           -------------------------------- 306
LATS2           -------------------------------- 306
NDR1            -------------------------------- 294
NDR2            -------------------------------- 294
MAST1           -------------------------------- 274
MAST4           -------------------------------- 238
MAST2           -------------------------------- 274
MAST3           -------------------------------- 274
MRCKA           -------------------------------- 267
MRCKB           -------------------------------- 267
DMPK2           -------------------------------- 267
DMPK1           -------------------------------- 269
ROCK1           -------------------------------- 263
ROCK2           -------------------------------- 263
CRIK            -------------------------------- 264
MASTL           -------------------------------- 276
1O6LA           -------------------------------- 260
AKT2            -------------------------------- 258
AKT1            -------------------------------- 259
AKT3            -------------------------------- 258
MSK1            -------------------------------- 270
MSK2            -------------------------------- 269
P70S6K          -------------------------------- 262
P70S6KB         -------------------------------- 262
RSK1            -------------------------------- 260
RSK3            -------------------------------- 260
RSK2            -------------------------------- 260
RSK4            -------------------------------- 258
1FOTA           -------------------------------- 257
1CDKA           -------------------------------- 255
PKACA           -------------------------------- 255
PKACB           -------------------------------- 255
PKACG           -------------------------------- 255
PRKX            -------------------------------- 255
PRKY            -------------------------------- 217
PKCA            -------------------------------- 259
PKCB            -------------------------------- 259
PKCG            -------------------------------- 264
PKCE            -------------------------------- 261
PKCH            -------------------------------- 260
PKCD            -------------------------------- 255
PKCT            -------------------------------- 255
PKCI            -------------------------------- 269
PKCZ            -------------------------------- 267
PKN1            -------------------------------- 260
PKN2            -------------------------------- 260
PKN3            -------------------------------- 260
SGK             -------------------------------- 258
SGK2            -------------------------------- 258
SGK3            -------------------------------- 258
PKG1            -------------------------------- 260
PKG2            -------------------------------- 259
AURB            -------------------------------- 251
AURC            -------------------------------- 251
AURA            -------------------------------- 251
AURORA2_AVE     -------------------------------- 240
PLK1            -------------------------------- 253
PLK2            -------------------------------- 253
PLK3            -------------------------------- 253
PLK4            -------------------------------- 254
NEK11           -------------------------------- 259
YANK1           -------------------------------- 259
YANK2           -------------------------------- 261
YANK3           -------------------------------- 261
SGK494          -------------------------------- 253
DOMAIN2_MSK1    -------------------------------- 262
DOMAIN2_MSK2    -------------------------------- 258
DOMAIN2_RSK1    -------------------------------- 258
DOMAIN2_RSK2    -------------------------------- 258
DOMAIN2_RSK3    -------------------------------- 258
DOMAIN2_RSK4    -------------------------------- 258
DRAK1           -------------------------------- 261
DRAK2           -------------------------------- 261
1JKSA           -------------------------------- 265
DAPK1           -------------------------------- 263
DAPK3           -------------------------------- 263
DAPK2           -------------------------------- 263
SGK085          -------------------------------- 256
CAMLCK          -------------------------------- 256
SKMLCK          -------------------------------- 256
SMMLCK          -------------------------------- 256
1KOBA           -------------------------------- 256
1TKIA           -------------------------------- 255
TTN             -------------------------------- 255
PKD1            -------------------------------- 257
PKD3            -------------------------------- 257
PKD2            -------------------------------- 257
PSKH1           -------------------------------- 258
PSKH2           -------------------------------- 258
CAMK1A          -------------------------------- 257
CAMK1D          -------------------------------- 257
CAMK1B          -------------------------------- 256
CAMK1G          -------------------------------- 255
CAMK4           -------------------------------- 255
DCAMKL1         -------------------------------- 258
DCAMKL2         -------------------------------- 258
DCAMKL3         -------------------------------- 258
CHK2            -------------------------------- 267
MAPKAPK2        -------------------------------- 262
MAPKAPK3        -------------------------------- 261
MAPKAPK5        -------------------------------- 283
MNK1            -------------------------------- 286
MNK2            -------------------------------- 285
VACAMKL         -------------------------------- 235
GCK             -------------------------------- 258
KHS1            -------------------------------- 258
KHS2            -------------------------------- 258
HPK1            -------------------------------- 258
MST1            -------------------------------- 252
MST2            -------------------------------- 252
MST3            -------------------------------- 251
YSK1            -------------------------------- 251
MST4            -------------------------------- 251
LOK             -------------------------------- 259
SLK             -------------------------------- 259
MAP3K4          -------------------------------- 259
MAP3K2          -------------------------------- 261
MAP3K3          -------------------------------- 261
MAP3K8          -------------------------------- 264
MAP3K5          -------------------------------- 264
MAP3K7          -------------------------------- 255
MAP3K6          -------------------------------- 254
PAK1            -------------------------------- 252
PAK3            -------------------------------- 252
PAK2            -------------------------------- 253
PAK4            -------------------------------- 252
PAK5            -------------------------------- 252
PAK6            -------------------------------- 252
OSR1            -------------------------------- 275
STLK3           -------------------------------- 275
TAO1            -------------------------------- 254
TAO3            -------------------------------- 254
TAO2            -------------------------------- 254
MYO3A           -------------------------------- 267
MYO3B           -------------------------------- 267
ZC1/HGK         -------------------------------- 265
ZC3/MINK        -------------------------------- 265
ZC2/TNIK        -------------------------------- 265
ZC4/NRK         -------------------------------- 289
MAP3K1          -------------------------------- 266
GAK             -------------------------------- 274
SGK495          -------------------------------- 171
TRB1            -------------------------------- 240
TRB2            -------------------------------- 245
TRB3            -------------------------------- 243
SSTK            -------------------------------- 256
TSSK3           -------------------------------- 256
TSSK1           -------------------------------- 261
TSSK2           -------------------------------- 261
TSSK4           -------------------------------- 269
HUNK            -------------------------------- 260
SNRK            -------------------------------- 254
NIM1            -------------------------------- 252
MELK            -------------------------------- 253
BRSK1           -------------------------------- 252
BRSK2           -------------------------------- 252
MARK1           -------------------------------- 252
MARK2           -------------------------------- 252
MARK3           -------------------------------- 252
MARK4           -------------------------------- 252
QIK             -------------------------------- 252
SIK             -------------------------------- 252
QSK             -------------------------------- 252
AMPKA1          -------------------------------- 253
AMPKA2          -------------------------------- 253
NUAK1           -------------------------------- 252
NUAK2           -------------------------------- 252
BIKE            INKCCKQLLRHGAL------------------ 291
AAK1            -------------------------------- 275
LIMK1           -------------------------------- 266
LIMK2           -------------------------------- 271
TESK1           -------------------------------- 258
TESK2           -------------------------------- 232
WNK1            -------------------------------- 259
WNK3            -------------------------------- 259
WNK2            -------------------------------- 259
WNK4            -------------------------------- 259
NEK10           -------------------------------- 267
NEK6            QQM----------------------------- 274
NEK7            -------------------------------- 252
NEK2            -------------------------------- 264
NEK1            -------------------------------- 255
NEK5            -------------------------------- 256
NEK3            -------------------------------- 254
NEK4            -------------------------------- 256
NEK8            -------------------------------- 248
NEK9            -------------------------------- 257
NRBP1           -------------------------------- 264
NRBP2           -------------------------------- 276
CLIK1           -------------------------------- 329
CLIK1L          -------------------------------- 333
STK33           -------------------------------- 266
DOMAIN2_GCN2    -------------------------------- 260
SCYL1           -------------------------------- 231
SCYL3           -------------------------------- 221
DOMAIN2_JAK1    -------------------------------- 265
DOMAIN2_TYK2    -------------------------------- 278
DOMAIN2_JAK2    -------------------------------- 265
DOMAIN2_JAK3    SSDYELLSDPTP-------------------- 273
ILK             -------------------------------- 257
LRRK1           F------------------------------- 284
PBK             -------------------------------- 287
WEE1            -------------------------------- 271
WEE1B           -------------------------------- 275
SGK071          -------------------------------- 269
PIK3R4          -------------------------------- 284
MSSK1           -------------------------------- 453
SRPK1           -------------------------------- 574
SRPK2           -------------------------------- 606
RSKL1           -------------------------------- 235
RSKL2           -------------------------------- 387
SGK396          -------------------------------- 242
VRK1            -------------------------------- 267
VRK2            -------------------------------- 264
VRK3            -------------------------------- 240
BUB1            -------------------------------- 268
BUBR1           -------------------------------- 265
SGK196          -------------------------------- 251
SGK493          -------------------------------- 228