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<ul class="toc">
<li class="level1"><div class="li"><span class="li"><a href="#drugs_database_schema_of_freediams" class="toc">Drugs database schema of FreeDiams</a></span></div>
<ul class="toc">
<li class="level2"><div class="li"><span class="li"><a href="#drugs_database" class="toc">Drugs database</a></span></div>
<ul class="toc">
<li class="level3"><div class="li"><span class="li"><a href="#name_of_the_drugs_database_file" class="toc">Name of the Drugs database file</a></span></div></li>
<li class="level3"><div class="li"><span class="li"><a href="#tables_of_the_database" class="toc">Tables of the database</a></span></div></li>
</ul>
</li>
<li class="level2"><div class="li"><span class="li"><a href="#interactions_database" class="toc">Interactions database</a></span></div>
<ul class="toc">
<li class="level3"><div class="li"><span class="li"><a href="#table_interactions" class="toc">Table INTERACTIONS</a></span></div></li>
<li class="level3"><div class="li"><span class="li"><a href="#table_interaction_knowledge" class="toc">Table INTERACTION_KNOWLEDGE</a></span></div></li>
</ul>
</li>
<li class="level2"><div class="li"><span class="li"><a href="#database_informations" class="toc">Database informations</a></span></div></li>
<li class="level2"><div class="li"><span class="li"><a href="#sql_schema_drugs_database" class="toc">SQL Schema : Drugs database</a></span></div></li>
<li class="level2"><div class="li"><span class="li"><a href="#sql_schema_interactions_database" class="toc">SQL Schema : Interactions database</a></span></div></li></ul>
</li></ul>
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<div class="plugin_include_content" id="plugin_include__en:manuals:drugswidget:drugsdatabaseschema">
<h1><a name="drugs_database_schema_of_freediams" id="drugs_database_schema_of_freediams">Drugs database schema of FreeDiams</a></h1>
<div class="level1">
<p>
<p><div class="notedoc">This page is up-to-date.
</div></p>
</p>
<p>
This section is written primarily for developers. FreeDiams is programmed to manage multiple
therapeutic databases. To add a data source, you just need to create a database
data meeting the criteria described below with SQLite.
</p>
</div>
<h2><a name="drugs_database" id="drugs_database">Drugs database</a></h2>
<div class="level2">
</div>
<h3><a name="name_of_the_drugs_database_file" id="name_of_the_drugs_database_file">Name of the Drugs database file</a></h3>
<div class="level3">
<p>
All drugs databases must use the above schema for their filename:
</p>
<ul>
<li class="level1"><div class="li"> No specific suffixe</div>
</li>
<li class="level1"><div class="li"> 'drugs' filename forbidden</div>
</li>
<li class="level1"><div class="li"> Mandatory extension : db</div>
</li>
<li class="level1"><div class="li"> Example : <em>drugs-usa.db</em></div>
</li>
</ul>
</div>
<h3><a name="tables_of_the_database" id="tables_of_the_database">Tables of the database</a></h3>
<div class="level3">
<p>
The database should contain several tables linked together through primary keys. <br/>
There is one for each drug <strong>unique identifier number (UID)</strong>. This unique identifier number
may have a special name (CIS for France, PZN Germany…). This designation
can be completed in the table INFORMATIONS.
</p>
<p>
The various tables are:
</p>
<ul>
<li class="level1"><div class="li"> DRUGS: contains the UID, the name of the drug and information on marketing;</div>
</li>
<li class="level1"><div class="li"> COMPOSITION: Contains a description of various molecules to the drug</div>
</li>
<li class="level1"><div class="li"> PACKAGING: contains the format of treatment (packaging)</div>
</li>
<li class="level1"><div class="li"> LK_MOL_ATC : contains links between code molecules and ATC codes (ids)</div>
</li>
</ul>
<p>
So far, FreeDiams does not take into account the table PACKAGING.
</p>
</div>
<h4><a name="the_drugs_table" id="the_drugs_table">The DRUGS table</a></h4>
<div class="level4">
<p>
Schema :
</p>
<ul>
<li class="level1"><div class="li"> UID : Unique Identifier for Drug, typically per-country</div>
</li>
<li class="level1"><div class="li"> NAME : Commercial, “brand” name of the drug</div>
</li>
<li class="level1"><div class="li"> FORM : Form of the drug (e.g. tablet, capsule, powder, solution, cream, soap bar)</div>
</li>
<li class="level1"><div class="li"> ROUTE : route of administration (e.g. oral, intravenous, ophthalmic, rectal, topical)</div>
</li>
<li class="level1"><div class="li"> ATC : drug's Anatomical Therapeutic Chemical classification system code</div>
</li>
<li class="level1"><div class="li"> GLOBAL_STRENGTH : contains the globale strenght of the drug. Only used for the drugs name construction. See also: </div>
</li>
</ul>
<p>
INFORMATIONS.DRUGS_NAME_CONSTRUCTOR.
</p>
<ul>
<li class="level1"><div class="li"> Ex : 2.5mg;6.5mg</div>
</li>
<li class="level3"><div class="li"> TYPE_MP (optional) : marketing permission (AMM in French, Schedule in CA)</div>
</li>
<li class="level3"><div class="li"> AUTHORIZATION (optional) : type of authorisation</div>
</li>
<li class="level3"><div class="li"> MARKETED : Boolean :: Yes = 1 ; No = 0</div>
</li>
<li class="level3"><div class="li"> LINK_SPC (optional) : internet link to a “summary of product characteristics”</div>
</li>
</ul>
</div>
<h4><a name="the_composition_table" id="the_composition_table">The COMPOSITION table</a></h4>
<div class="level4">
<p>
A drug can contain multiple molecules. One molecule can be present in a specific form and be
metabilized into another (see NATURE / LK_NATURE).
</p>
<p>
Schema:
</p>
<ul>
<li class="level1"><div class="li"> UID : UID of the drug</div>
</li>
<li class="level1"><div class="li"> MOLECULE_FORM : form of the drug (redundant with DRUGS.FORM)</div>
</li>
<li class="level1"><div class="li"> MOLECULE_CODE : unique identifier of the molecule</div>
</li>
<li class="level1"><div class="li"> MOLECULE_NAME : name of the molecule</div>
</li>
<li class="level1"><div class="li"> DOSAGE : molecule amount (per amount of form) e.g. “325 mg”</div>
</li>
<li class="level1"><div class="li"> DOSAGE_REF : reference amount of form e.g. “1 tablet”, “2 mL suspension”</div>
</li>
<li class="level1"><div class="li"> NATURE : must be one of two kinds :</div>
<ul>
<li class="level3"><div class="li"> SA (can be used as default value) : name of Active substance</div>
</li>
<li class="level3"><div class="li"> FT : name of Tranformed substance</div>
</li>
</ul>
</li>
<li class="level1"><div class="li"> LK_NATURE :</div>
<ul>
<li class="level3"><div class="li"> Link from SA to FT</div>
</li>
</ul>
</li>
</ul>
</div>
<h4><a name="the_lk_mol_atc_table" id="the_lk_mol_atc_table">The LK_MOL_ATC table</a></h4>
<div class="level4">
<p>
This table is essential for the calculation of drug interactions. <br/>
The interactions' search engine uses the molecular composition of drugs. Each molecule
must be linked to a code ATC (via its identifier from the database \e iam). Interactions are
calculated on the basis of ATC codes.
</p>
<p>
Schema :
</p>
<ul>
<li class="level1"><div class="li"> MOLECULE_CODE = link to COMPOSITION.MOLECULE_CODE</div>
</li>
<li class="level1"><div class="li"> ATC_ID = link to INTERACTION_DATABASE.ATC.ID (not the CODE)</div>
</li>
</ul>
</div>
<h4><a name="the_packaging_table" id="the_packaging_table">The PACKAGING table</a></h4>
<div class="level4">
<p>
This table is <em>optional</em>. <br/>
</p>
<p>
Schema :
</p>
<ul>
<li class="level1"><div class="li"> UID : UID of the Drug</div>
</li>
<li class="level1"><div class="li"> PACKAGE_UID : UID of the packaging</div>
</li>
<li class="level1"><div class="li"> LABEL : label of the packaging</div>
</li>
<li class="level1"><div class="li"> STATUS :</div>
<ul>
<li class="level3"><div class="li"> Active packaging → A</div>
</li>
<li class="level3"><div class="li"> Inactive packaging → B</div>
</li>
</ul>
</li>
<li class="level1"><div class="li"> MARKETING :</div>
<ul>
<li class="level3"><div class="li"> Marketing cancelled → A</div>
</li>
<li class="level3"><div class="li"> Unknown Marketing date → N</div>
</li>
<li class="level3"><div class="li"> Commercialized → C</div>
</li>
<li class="level3"><div class="li"> Suspended Marketing → S</div>
</li>
</ul>
</li>
<li class="level1"><div class="li"> DATE : most recent commercial update</div>
</li>
<li class="level1"><div class="li"> OPTIONAL_CODE : can complete the MAIN_CODE</div>
</li>
</ul>
</div>
<h4><a name="the_informations_table" id="the_informations_table">The INFORMATIONS table</a></h4>
<div class="level4">
<p>
Schema :
</p>
<ul>
<li class="level1"><div class="li"> VERSION : Version of the db (please be read the page : \ref versionning). See this as a primary key. FreeDiams will read the first </div>
</li>
</ul>
<p>
selected row of the database as database informations.
</p>
<ul>
<li class="level1"><div class="li"> NAME : Name of the database to display to the user. Translations are supported using syntax 'two-character <acronym title="International Organization for Standardization">ISO</acronym> language code=name', </div>
</li>
</ul>
<p>
unquoted, without any egal sign in the name and with line breaks delimiting multiple languages (see below).
</p>
<ul>
<li class="level1"><div class="li"> <code></div>
</li>
</ul>
<p>
fr=French name
en=English name
sp=Spanish
de=Deutsch
xx=All other languages
</code
</p>
<ul>
<li class="level1"><div class="li"> IDENTIFIANT : unique identifiant for FreeDiams.</div>
<ul>
<li class="level3"><div class="li"> This identifiant must be unique for all drugs databases provided for FreeDiams</div>
</li>
<li class="level3"><div class="li"> French AFFSSAPS database = “FR_AFSSAPS”</div>
</li>
<li class="level3"><div class="li"> FDA database = “USA_FDA”;</div>
</li>
<li class="level3"><div class="li"> Canadian database = “CANADIAN”;</div>
</li>
</ul>
</li>
<li class="level1"><div class="li"> COMPAT_VERSION : FreeDiams application version dependency</div>
</li>
<li class="level1"><div class="li"> PROVIDER : Provider of the datas (eg FDA)</div>
</li>
<li class="level1"><div class="li"> WEBLINK : Web site of the provider</div>
</li>
<li class="level1"><div class="li"> COMPLEMENTARY_WEBSITE : Web site of additionnal informations on the database</div>
</li>
<li class="level1"><div class="li"> AUTHOR : Author of the database (eg Me)</div>
</li>
<li class="level1"><div class="li"> LICENSE :</div>
</li>
<li class="level1"><div class="li"> DATE : Date of release; format MUST BE formatted : yyyy-MM-dd</div>
</li>
<li class="level1"><div class="li"> DRUG_UID_NAME : Name to use for the drug UID</div>
</li>
<li class="level1"><div class="li"> PACK_MAIN_CODE_NAME : Name to for the packaging main code</div>
</li>
<li class="level1"><div class="li"> ATC : boolean ; ATC is available for each drugs in the database</div>
</li>
<li class="level1"><div class="li"> INTERACTIONS : boolean : manages interactions</div>
</li>
<li class="level1"><div class="li"> AUTHOR_COMMENTS : place to hold your comment</div>
</li>
<li class="level1"><div class="li"> LANGUAGE_COUNTRY : language and country specificity. Format = language_country where :</div>
<ul>
<li class="level3"><div class="li"> language is a lowercase, two-letter, <acronym title="International Organization for Standardization">ISO</acronym> 639 language code,</div>
</li>
<li class="level3"><div class="li"> territory is an uppercase, two-letter, <acronym title="International Organization for Standardization">ISO</acronym> 3166 country code,</div>
</li>
<li class="level3"><div class="li"> and codeset and modifier are ignored.</div>
</li>
</ul>
</li>
<li class="level1"><div class="li"> DRUGS_NAME_CONSTRUCTOR : string to use for the drug name construction. Some tokens will be replaced by their values. You can use these </div>
</li>
</ul>
<p>
tokens :
</p>
<ul>
<li class="level1"><div class="li"> NULL value is replaced by “NAME” only</div>
</li>
<li class="level3"><div class="li"> “NAME” : for the name of the drug ( == DRUGS.NAME)</div>
</li>
<li class="level3"><div class="li"> “FORM” : for the name of the drug ( == DRUGS.FORM)</div>
</li>
<li class="level3"><div class="li"> “ROUTE” : for the name of the drug ( == DRUGS.ROUTE)</div>
</li>
<li class="level3"><div class="li"> “GLOBAL_STRENGTH” : for the name of the drug ( == DRUGS.GLOBAL_STRENGTH)</div>
</li>
<li class="level3"><div class="li"> Eg : NAME, FORM (GLOBAL_STRENGTH) == AMOXICILLINE, TABLETS (1g)</div>
</li>
<li class="level3"><div class="li"> Eg : NAME, FORM, ROUTE - * GLOBAL_STRENGTH == AMOXICILLINE, TABLETS, ORAL - * 1g</div>
</li>
</ul>
</div>
<h4><a name="the_search_engines_table" id="the_search_engines_table">The SEARCH_ENGINES table</a></h4>
<div class="level4">
<p>
This table allow developpers to add search engines to help users. These search engines will
be added to the Protocol Creator Dialog under the button <em>Help and Informations</em>.
</p>
<p>
Available tokens:
</p>
<ul>
<li class="level1"><div class="li"> <em>[[ONE_ATC_CODE]] </em>–> 1 ATC CODE == 1 more link</div>
</li>
<li class="level1"><div class="li"> <em>[[DRUG_ATC]]</em> –> if known the DRUGS.ATC value (ATC code)</div>
</li>
<li class="level1"><div class="li"> <em>[[ATC_CODES]]</em> –> all know ATC Codes of the drug (and its molecular components)</div>
</li>
<li class="level1"><div class="li"> <em>[[ATC_LABELS]]</em> –> all known ATC Label of the drug (and its molecular components)</div>
</li>
<li class="level1"><div class="li"> <em>[[DRUG_NAME]]</em> –> exact value of the DRUGS.NAME field</div>
</li>
<li class="level1"><div class="li"> <em>[[CONSTRUCTED_DRUG_NAME]] </em>–> the constructed drug name like inform in the INFORMATIONS.DRUGS_NAME_CONSTRUCTOR</div>
</li>
<li class="level1"><div class="li"> <em>[[DRUG_UID]]</em> –> the UID of the drug</div>
</li>
</ul>
</div>
<h2><a name="interactions_database" id="interactions_database">Interactions database</a></h2>
<div class="level2">
<p>
Interactions are calculated from ATC code of each components of drugs.<br/>
Some components are grouped into “interactions classes” which are shown in the ATC classification
under the codes <em>ZXX</em>.<br/>
Each drugs databases that provides links from their components to ATC codes, give the
possibilities to calculate the drugs interactions.
</p>
</div>
<h3><a name="table_interactions" id="table_interactions">Table INTERACTIONS</a></h3>
<div class="level3">
<p>
Is mainly a link table.
</p>
<ul>
<li class="level1"><div class="li"> ID : unique identifier of the interaction</div>
</li>
<li class="level1"><div class="li"> ATC_ID1 : link to ATC.ID of the first interacting molecule or class</div>
</li>
<li class="level1"><div class="li"> ATC_ID2 : link to ATC.ID of the second interacting molecule or class</div>
</li>
<li class="level1"><div class="li"> INTERACTION_KNOWLEDGE_ID : link to the INTERACTION_KNOWLEDGE</div>
</li>
</ul>
</div>
<h3><a name="table_interaction_knowledge" id="table_interaction_knowledge">Table INTERACTION_KNOWLEDGE</a></h3>
<div class="level3">
<p>
This table contains the content of the interaction.
</p>
<ul>
<li class="level1"><div class="li"> ID : unique identifier</div>
</li>
<li class="level1"><div class="li"> TYPE : type of interaction (encoded string)</div>
<ul>
<li class="level3"><div class="li"> I : Information</div>
</li>
<li class="level3"><div class="li"> P = Precaution</div>
</li>
<li class="level3"><div class="li"> T = Take in account</div>
</li>
<li class="level3"><div class="li"> D = Inadvisable</div>
</li>
<li class="level3"><div class="li"> C = Contraindication</div>
</li>
</ul>
</li>
<li class="level1"><div class="li"> RISK_FR : risk content in french</div>
</li>
<li class="level1"><div class="li"> MANAGEMENT_FR : management of the interaction in french</div>
</li>
<li class="level1"><div class="li"> RISK_EN : risk content in english</div>
</li>
<li class="level1"><div class="li"> MANAGEMENT_EN : management of the interaction in english</div>
</li>
<li class="level1"><div class="li"> <acronym title="Extensible Markup Language">XML</acronym> : <acronym title="Extensible Markup Language">XML</acronym> encoded (future use)</div>
</li>
</ul>
</div>
<h2><a name="database_informations" id="database_informations">Database informations</a></h2>
<div class="level2">
<p>
Drugs databases are stored inside <em> /Resources/databases/drugs</em>.<br/>
You can use whatever file name you want. File name must end with <em>.db</em> file extension. The INFORMATIONS
table will be examinated. If it does not contains errors, the drugs database will be concidered as
usable by FreeDiams.
</p>
</div>
<h2><a name="sql_schema_drugs_database" id="sql_schema_drugs_database">SQL Schema : Drugs database</a></h2>
<div class="level2">
<p>
<a href="http://code.google.com/p/freemedforms/source/browse/trunk/global_resources/sql/drugs_schema.sql&DokuWiki=effe18656d1fd249939f3127a7b4aebc" class="media mediafile mf_sql" title="http://code.google.com/p/freemedforms/source/browse/trunk/global_resources/sql/drugs_schema.sql">External link</a>
</p>
</div>
<h2><a name="sql_schema_interactions_database" id="sql_schema_interactions_database">SQL Schema : Interactions database</a></h2>
<div class="level2">
<p>
<a href="http://code.google.com/p/freemedforms/source/browse/trunk/global_resources/sql/iam_schema.sql&DokuWiki=effe18656d1fd249939f3127a7b4aebc" class="media mediafile mf_sql" title="http://code.google.com/p/freemedforms/source/browse/trunk/global_resources/sql/iam_schema.sql">External link</a>
</p>
</div>
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<abbr class="published" title="2010-09-27T13:56:49Z">2010/09/27 13:56</abbr><div class="tags"><span>
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en/manuals/freediams/drugsdatabaseschema.txt · Dernière modification: 2010/10/09 23:09 par Eric Maeker, MD </div>
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