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<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN">
<html>
<head>
	<meta name="KeyWords"
			 content="PAL, phylogenetic analysis library, molecular phylogenetics,
					molecular evolution, phylogeny,
								tree reconstruction, maximum likelihood">
	<meta name="Content-Type" content="text/html; charset=iso-8859-1">
	<meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1">
	<title>The PAL Project</title>
</head>
<body>

<table cellpadding="4" cellspacing="4" border="0" width="100%" height="100%">
		<tbody>
			<tr>
				<td valign="top">
					<table cellpadding="0" cellspacing="0" border="1" width="130" height = "500">
						<tbody>
							<tr>
								<td valign="top" bgcolor="#cccccc" align="center">
									<a href = "index.html">About</a>
									<br>
									<a href = "people.html"> People Involved </a>
									<br>
									<a href = "features.html">Features</a>
									<br>
									<a href = "user_interfaces.html">User Interfaces</a>
									<br>
									<a href = "related.html">Related Projects</a>
									<br>
									<br>
									<a href = "download.html">Downloads and Installation</a>
									<br>
									<b>History</b>
									<br>
									<br>
									<a href = "contributing.html">Contributing</a>
									<br>
									<a href = "acknowledgements.html">Acknowledgements</a>
									<br>
									<br>
									<a href = "online.html">Pal Online</a>
								</td>
							</tr>
						</tbody>
					</table>
				</td>
				<td valign="top">
	<!-- Start of normal block -->

<img src=pal.gif hspace=10 align=left ALT="PAL icon">
<strong><font size="+2">PAL: Phylogenetic Analysis Library</font></strong>
<br>

<strong><em>
<center>PAL Release History</center>
</em></strong>

PAL was first publicly distributed  in September 1999.
This and all subsequent releases can be downloaded by clicking
on the corresponding version number.

<table CELLPADDING=2 >
	<tr VALIGN=TOP>
		<td><a href="bin/pal-1.5-src.zip">1.5 (src)</a>, or <a href="bin/pal-1.5.jar">1.5 (precompiled jar)</a>
		<td>
			Substatial class rearrangement.
			New alignment reading code.
			Faster likelihood calculation.
			ML tree searching for unrooted trees.
			More comprehensive sUPGMA.
			New src managment files (newmake.bat, and build.xml for ant).
			New Codon Tables.
			New tree rooting classes (with mid-point rooting).
			Faster evolutionary distance calculation.
			More Clustering methods.
			Selection codon models (M2 and M3).
			Tree label colouring, and font changing.
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-1.4.tar.gz">1.4</a></td>

		<td>
			Two new packages, pal.popgen and pal.xml.  Estimation of linkage disequilibrium.
			Faster likelihood calculations.  Improvement of tree classes and associated
			functions. Many new helper functions. Classes dealing with XML.
			(January 2002).
		</td>
	</tr>


	<tr VALIGN=TOP>
		<td><a href="bin/pal-1.3.tar.gz">1.3</a></td>
		<td>
		Change of license from GPL to LGPL.  Otherwise minor changes, e.g., updated
		skyline plot class.
		 (July 2001).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-1.2.tar.gz">1.2</a></td>
		<td>
			Codon models implemented (rate matrix, alignment, codon translation methods).
			Utility functions for alignments (score function etc.). Splits, split systems
			and corresponding tree distances (Robinson-Foulds).  Extended utility
			functions for trees (incl. Node factory). Pareto distribution.  Classes for "measurably evolving
			populations" (mep package). (April 2001).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-1.1.tar.gz">1.1</a></td>
		<td>
			Improvement of coalescent package: generalized skyline plot, new const.-to-exp.
			growth demographic model, new features in IntervalsExtractor, new
			classes DemographicTree/ClockTree.  Reorganization of math and statistics
			packages: new binomial, error and gamma functions in math package, and
			bootstrap statistics (BIAS, VAR, CI etc), gamma, exponential, chi-square,
			and normal distributions with pdf, cdf, and quantiles in statistics
			package. New features in TreeUtils and NodeUtils, allowing for
			a smaller SimpleTree class. SUPGMA tree reconstruction and distances.
			Nucleotide-to-amino acid translation class. More GUI classes, e.g., for
			circular trees.  (December 2000).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-1.0.tar.gz">1.0</a></td>
		<td>
			Tree and Node classes turned into Interfaces implemented by SimpleNode and SimpleTree
			and controlled by TreeUtils and NodeUtils classes.
			New ParameterizedTree: Clock-trees with dated tips.
			Much better accuracy and vast speed-ups in algorithm for
			ML optimization of branch lengths for UnconstrainedTree, ClockTree, DatedTipsClockTree
			(optimization delivers now "real-world" performance).
			New tree comparison tests (e.g., Shimodaira-Hasegawa).
			New protein models (VT, WAG, CPREV).
			New classes for demographic models, coalescent simulation and coalescent priors.
			Package names changed (clearer longer names), some classes reorganized, and two new packages
			introduced (coalescent and util).
			Sorting class.
			Macintosh compatibility (some file names changed). (July 2000).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-0.9.zip">0.9</a></td>

		<td>
			Formation of PAL Development Core Team. PAL converted to pure library
			(command applications moved into the Vanilla package). More efficient multivariate
			minimization classes (non-linear conjugate gradient algorithms, line function
			with boundaries, conjugate direction method with boundaries etc.) and improved
			stop criteria. Automatic model selection among amino acids matrices. Inclusion
			of the VT rate matrix. Estimation of model parameters without a tree. Several
			smaller bug fixes and changes (alias mapping in Tree reversed plus subsequent
			changes in TreeDistance and LikelihoodValue). (April 2000).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-0.8.zip">0.8</a></td>
		<td>
			All classes are now fully documented using JavaDoc comments. Source
			code complies to Java 1.0 language standard to allow compilation into native
			code. Classes for evaluation of evolutionary hypotheses (chi-square and
			likelihood computation) and interfaces for functions and of Parameterized
			are reorganized. Detail improvements in a number of other classes. Introduction
			of clock-constraint on trees. Some minor bug fixes. New platforms: direct
			support for Windows and Unix-native (includes instructions for compilation
			into native code using the GNU Compiler for Java). New applications: UPGMA
			(constructs UPGMA tree), STRIPSITES (strips sites from an alignment according
			to a given order). LSTREE and MLTREE now enable the estimation of clock-like
			branch lengths. (February 2000).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-0.7.tar.gz">0.7</a></td>
		<td>
			Dog icon. Much improved classes for formatted input and output. PHYLIP
			sequential format added. Restructuring of alignment package (e.g., removal
			of TypedAlignment, changes in SitePattern, automatic data type detection).
			Introduction of getInstance() methods in DataType and RateMatrix. Objects
			for computing tree-induced distances and (weighted) squared distances between
			distance matrices. Class for computing least-square branch length estimates.
			CUI frontend now in a single common class for all CUI programs. New applications:
			EVOLVE (generation of artificial data sets), LSTREE (least-squares estimates
			of branch lengths), JUMBLE (randomizes sequence input order). (December
			1999).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-0.6.tar.gz">0.6</a></td>
		<td>
			Complete reorganization of package layout and all classes. Main new
			classes: ML evaluation of trees, estimation of model and branch parameters,
			global optimization (genetic algorithm), likelihood ratio and Kishino-Hasegawa-Templeton
			tests, random number generator, numerical derivatives of vectors. New application:
			MLTREE (computation of likelihoods given a tree and estimation of model
			parameters and branch lengths). Improvement of MLDIST program. (November1999).
		</td>
	</tr>

	<tr VALIGN=TOP>
		<td><a href="bin/pal-0.5.tar.gz">0.5</a></td>
		<td>First public release. (September 1999).</td>
	</tr>

	<tr VALIGN=TOP>
		<td>-</td>
		<td>Project start. (January 1999).</td>
	</tr>
</table>

	<!-- End of normal block -->


				</td>
			</tr>

	</tbody>
</table>
	<br>

</body>
</html>

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