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<?xml version='1.0' encoding='UTF-8'?>
<!-- XML Authors: Corinne Maufrais, Nicolas Joly and Bertrand Neron,             -->
<!-- 'Biological Software and Databases' Group, Institut Pasteur, Paris.         -->
<!-- Distributed under LGPLv2 License. Please refer to the COPYING.LIB document. -->
<program>
  <head>
    <name>lvb</name>
    <version>2.3</version>
    <doc>
      <title>LVB</title>
      <description>
        <text lang="en">Reconstructing Evolution With Parsimony And Simulated Annealing</text>
      </description>
      <authors>D. Barker</authors>
      <reference>Barker, D. 2004. LVB: Parsimony and simulated annealing in the search for phylogenetic trees. Bioinformatics, 20, 274-275.</reference>
      <doclink>http://biology.st-andrews.ac.uk/cegg/lvb.htm</doclink>
      <homepagelink>http://biology.st-andrews.ac.uk/cegg/lvb.htm</homepagelink>
      <sourcelink>http://biology.st-andrews.ac.uk/cegg/lvb.htm</sourcelink>
    </doc>
    <category>phylogeny:parsimony</category>
  </head>
  <parameters>
    <parameter iscommand="1" ishidden="1">
      <name>lvb</name>
      <type>
        <datatype>
          <class>String</class>
        </datatype>
      </type>
      <format>
        <code proglang="perl">"lvb &lt;lvb.params"</code>
        <code proglang="python">"lvb &lt;lvb.params"</code>
      </format>
      <argpos>0</argpos>
    </parameter>
    <parameter ismandatory="1">
      <name>infile</name>
      <prompt lang="en">Alignment File</prompt>
      <type>
        <datatype>
          <class>Alignment</class>
        </datatype>
        <dataFormat>PHYLIPI</dataFormat>
      </type>
      <precond>
        <code proglang="perl">$infile ne "infile"</code>
        <code proglang="python">infile != "infile"</code>
      </precond>
      <format>
        <code proglang="perl">"ln -s $value infile; "</code>
        <code proglang="python">"ln -s " + str(value) + " infile; "</code>
      </format>
      <argpos>-1</argpos>
    </parameter>
    <parameter ishidden="1">
      <name>format</name>
      <prompt lang="en">Format is INTERLEAVED or SEQUENTIAL</prompt>
      <type>
        <datatype>
          <class>Choice</class>
        </datatype>
      </type>
      <vdef>
        <value>I</value>
      </vdef>
      <vlist>
        <velem>
          <value>I</value>
          <label>INTERLEAVED (I)</label>
        </velem>
        <velem>
          <value>S</value>
          <label>SEQUENTIAL (S)</label>
        </velem>
      </vlist>
      <format>
        <code proglang="perl">"$value\\n"</code>
        <code proglang="python">str(value) + "\n"</code>
      </format>
      <argpos>1</argpos>
      <paramfile>lvb.params</paramfile>
    </parameter>
    <parameter>
      <name>gaps_treatment</name>
      <prompt lang="en">Treatment of gaps represented by '-' </prompt>
      <type>
        <datatype>
          <class>Choice</class>
        </datatype>
      </type>
      <vdef>
        <value>U</value>
      </vdef>
      <vlist>
        <velem>
          <value>U</value>
          <label>UNKNOWN (U)</label>
        </velem>
        <velem>
          <value>F</value>
          <label>FIFTH STATE (F)</label>
        </velem>
      </vlist>
      <format>
        <code proglang="perl">"$value\\n"</code>
        <code proglang="python">str(value) + "\n"</code>
      </format>
      <argpos>2</argpos>
      <comment>
        <text lang="en">A gap represented by the letter 'O' in the data matrix is always treated as a character state in its own right (fifth state). lvb can treat gaps represented by'-' in either of the following ways:</text>
        <text lang="en">Fifth state '-' is treated as equivalent to 'O'. </text>
        <text lang="en">Unknown '-' is treated as equivalent to '?', i.e., as an ambiguous site that may contain 'A' or 'C' or 'G' or 'T' or 'O'. </text>
        <text lang="en">'Fifth state' may give excessive weight to multi-site gaps, since each affected base will be counted as one event.</text>
      </comment>
      <paramfile>lvb.params</paramfile>
    </parameter>
    <parameter>
      <name>seed</name>
      <prompt lang="en">Seed for the random number generator</prompt>
      <type>
        <datatype>
          <class>Integer</class>
        </datatype>
      </type>
      <format>
        <code proglang="perl">(defined $value)? "$value\\n" : "\\n"</code>
        <code proglang="python">( "\n" , str(value) + "\n" )[ value is not None ]</code>
      </format>
      <argpos>3</argpos>
      <comment>
        <text lang="en">When prompted for the random number seed, enter an integer in the range 0 to 900000000 inclusive. The default value is taken from the system clock and hence will vary from one analysis to the next, changing every second. The default is usually appropriate.</text>
      </comment>
      <paramfile>lvb.params</paramfile>
    </parameter>
    <parameter ismandatory="1">
      <name>bootstrap</name>
      <prompt lang="en">How many bootstrap replicates required (bootstrap)</prompt>
      <type>
        <datatype>
          <class>Integer</class>
        </datatype>
      </type>
      <vdef>
        <value>0</value>
      </vdef>
      <format>
        <code proglang="perl">"$value\\n"</code>
        <code proglang="python">str(value) + "\n"</code>
      </format>
      <ctrl>
        <message>
          <text lang="en">This server allows no more than 1000 replicates</text>
        </message>
        <code proglang="perl">$bootstrap &lt; 1000</code>
        <code proglang="python">bootstrap &lt;= 1000</code>
      </ctrl>
      <argpos>5</argpos>
      <comment>
        <text lang="en">Number of bootstrap replicates required as an integer in the range 1 to 1000 inclusive, or 0 for no bootstrapping (this server allows no more than 1000 replicates)</text>
      </comment>
      <paramfile>lvb.params</paramfile>
    </parameter>
    <parameter isout="1">
      <name>res</name>
      <prompt>Tree file</prompt>
      <type>
        <datatype>
          <class>Tree</class>
        </datatype>
        <dataFormat>NEWICK</dataFormat>
      </type>
      <filenames>
        <code proglang="perl">"outtree"</code>
        <code proglang="python">"outtree"</code>
      </filenames>
    </parameter>
    <parameter isout="1">
      <name>other_results</name>
      <prompt>Results files</prompt>
      <type>
        <datatype>
          <class>Text</class>
        </datatype>
      </type>
      <filenames>
        <code proglang="perl">"stat*"</code>
        <code proglang="perl">"sum"</code>
        <code proglang="perl">"log"</code>
        <code proglang="perl">"data"</code>
        <code proglang="perl">"ini*"</code>
        <code proglang="python">"stat*"</code>
        <code proglang="python">"sum"</code>
        <code proglang="python">"log"</code>
        <code proglang="python">"data"</code>
        <code proglang="python">"ini*"</code>
      </filenames>
    </parameter>
  </parameters>
</program>